D:Hyperalgesia

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Disease Term
Synonyms Hyperalgesia Primary, HYPERALGESIA SECONDARY, Hyperalgesia Tactile, HYPERALGESIA THERMAL, Hyperalgesias, Hyperalgesias Primary, HYPERALGESIAS SECONDARY, HYPERALGESIAS TACTILE, Hyperalgesias Thermal, Hyperalgesic, HYPERALGESIC SENSATION
Documents 6953
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hyperalgesia. They are ordered first by their relevance to Hyperalgesia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52 100.00
2 INT96652 F2rl1 Positive_regulation of Tac1 1 0.47 2.62 2.25 100.00
3 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78 100.00
4 INT103332 Ngf Regulation of Gene_expression of TRPV1 3 0.09 2.6 2.4 100.00
5 INT140532 Gtf3a Positive_regulation of DYT10 1 0.12 1.83 1.34 100.00
6 INT140531 Ngf Positive_regulation of DYT10 1 0.72 1.83 1.34 100.00
7 INT128604 Casp1 Positive_regulation of Gene_expression of Fos 1 0.10 0.55 0.59 100.00
8 INT128606 Pomc Positive_regulation of Gene_expression of Fos 1 0.02 0.55 0.59 100.00
9 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95 100.00
10 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93 100.00
11 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93 100.00
12 INT147660 Positive_regulation of Prkce Positive_regulation of TRPV1 1 0.04 0.69 1.12 100.00
13 INT121730 Pik3cb Regulation of Trpv1 1 0.58 0.54 1.09 100.00
14 INT156545 Il13 Positive_regulation of Gene_expression of Il12a 1 0.27 1.56 1.13 100.00
15 INT120313 Gnrhr Negative_regulation of Mmp2 1 0.03 0.85 1.07 100.00
16 INT96241 Il13 Negative_regulation of Tnf 1 0.08 0.6 0.59 100.00
17 INT96240 Il13 Negative_regulation of Il1b 1 0.17 0.6 0.59 100.00
18 INT120315 Gnrhr Negative_regulation of Positive_regulation of Ngf 1 0.11 0.85 1.07 100.00
19 INT120318 Gnrhr Negative_regulation of Ngf 1 0.11 0.85 1.07 100.00
20 INT128811 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Casp1 1 0.06 0.35 0.61 100.00
21 INT283932 Positive_regulation of Mapk14 Regulation of Gene_expression of Trpv1 1 0.14 1.28 0.99 100.00
22 INT51224 Gal Negative_regulation of Localization of Oxt 1 0.27 0.39 0.51 100.00
23 INT89514 Pnoc Regulation of Gene_expression of Fos 1 0.47 0.98 0.93 100.00
24 INT89515 Pnoc Regulation of Gene_expression of Fosl1 1 0.09 0.98 0.93 100.00
25 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47 100.00
26 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47 100.00
27 INT276865 Regulation of Trpv1 Regulation of Gene_expression of Gpr65 1 0.25 0.62 0.76 100.00
28 INT356284 Ptger2 Positive_regulation of Prkaca 1 0.00 0.39 0.37 100.00
29 INT121725 Binding of Trpv1 and Pik3cb 1 0.35 0.62 1.15 100.00
30 INT190775 Gene_expression of Il4 Negative_regulation of Positive_regulation of FOSL1 1 0.39 2.42 1.4 100.00
31 INT76508 Pnoc Regulation of Oprl1 1 0.47 0.25 1.32 100.00
32 INT109016 Negative_regulation of Prkg1 Negative_regulation of Positive_regulation of PRKG1 1 0.06 0.28 0.26 100.00
33 INT128700 BBS9 Negative_regulation of Il12a 1 0.47 0.76 1.03 99.96
34 INT160985 Urb1 Negative_regulation of Negative_regulation of Faah 1 0.41 1.36 0.74 99.96
35 INT147659 Prkce Positive_regulation of TRPV1 1 0.04 1.42 2.43 99.90
36 INT131819 Binding of Cpox and Nfkb1 1 0.15 0.44 0.46 99.90
37 INT249485 Trib3 Negative_regulation of Phosphorylation of Grin2b 1 0.02 0.64 0.68 99.82
38 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66 99.82
39 INT143941 Il1f5 Negative_regulation of Gene_expression of Fos 1 0.00 1.03 1.11 99.80
40 INT106558 Binding of Ntrk2 and Ntrk3 3 0.52 2.51 2.28 99.78
41 INT141911 Arih2 Regulation of Positive_regulation of Cpox 1 0.01 1.19 0.76 99.72
42 INT141910 Arih2 Regulation of Cpox 1 0.01 1.19 0.76 99.72
43 INT182558 Binding of Ptgir and Trpv1 1 0.16 1.12 1.37 99.68
44 INT169603 Nppb Regulation of Npr1 1 0.26 0.95 0.69 99.68
45 INT112514 Binding of Prkaca and Trib3 1 0.03 1.18 1.9 99.66
46 INT112515 Binding of Ephb1 and Trib3 1 0.06 0.41 0.65 99.66
47 INT112516 Binding of Prkce and Trib3 1 0.01 0.4 0.64 99.66
48 INT90121 Nos1 Regulation of Fos 1 0.27 0.25 0.49 99.64
49 INT149628 Il1b Regulation of Gene_expression of Ptgs2 1 0.30 0.84 0.84 99.64
50 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36 99.62
51 INT142437 Urb1 Negative_regulation of Faah 3 0.41 2.12 1.66 99.60
52 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61 99.56
53 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84 99.52
54 INT116777 Psma5 Positive_regulation of Binding of Fn1 1 0.01 1.24 1.06 99.48
55 INT262578 Prkaca Positive_regulation of Localization of Calca 1 0.03 0.71 0.75 99.48
56 INT112517 Binding of Ephb1 and Prkaca 3 0.18 0.58 1.85 99.46
57 INT112513 Binding of Prkaca and Prkce 1 0.04 0.4 0.64 99.46
58 INT228457 Negative_regulation of Ins1 Positive_regulation of Gene_expression of Trpv1 1 0.05 1.01 0.21 99.44
59 INT153685 Binding of Bcl2l11 and Gtpbp4 1 0.08 0.76 0.93 99.40
60 INT90131 NOS1 Regulation of Fos 1 0.00 0.25 0.49 99.40
61 INT139987 Oprm1 Positive_regulation of Localization of Oprl1 1 0.16 0.17 1.35 99.40
62 INT77791 fut10 Regulation of Regulation of Tnfrsf1a 1 0.02 0.85 0.36 99.34
63 INT86413 Pomc Regulation of Cor 1 0.01 0.17 0.3 99.32
64 INT81657 Binding of CPOX and PTGS1 5 0.15 1.9 2.37 99.28
65 INT68160 Alox5 Positive_regulation of Positive_regulation of Pla2g1b 1 0.03 0.64 1.13 99.26
66 INT68164 Mthfs Positive_regulation of Positive_regulation of Alox5 1 0.00 0.64 1.13 99.26
67 INT68167 Alox5 Positive_regulation of Positive_regulation of Mthfs 1 0.00 0.64 1.13 99.26
68 INT68157 Alox5 Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.13 99.26
69 INT68156 Pla2g1b Positive_regulation of Positive_regulation of Alox5 1 0.03 0.64 1.13 99.26
70 INT68159 Pla2g1b Positive_regulation of Positive_regulation of Pdpk1 1 0.05 0.64 1.12 99.26
71 INT68161 Mthfs Positive_regulation of Positive_regulation of Pla2g1b 1 0.03 0.64 1.12 99.26
72 INT68155 Pla2g1b Positive_regulation of Positive_regulation of Mthfs 1 0.03 0.64 1.12 99.26
73 INT68163 Mthfs Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.12 99.26
74 INT124088 Rab38 Negative_regulation of Mapk14 1 0.00 0.89 0.42 99.24
75 INT90120 Jun Positive_regulation of Gene_expression of Nos1 1 0.38 0.39 0.76 99.20
76 INT90117 Jun Regulation of Gene_expression of Nos1 1 0.21 0.39 0.76 99.20
77 INT90125 Nfkb1 Regulation of Gene_expression of Nos1 1 0.17 0.39 0.76 99.20
78 INT90116 Nfkb1 Positive_regulation of Gene_expression of Nos1 1 0.32 0.39 0.76 99.20
79 INT65724 Binding of Pnoc and Oprl1 8 0.33 2.94 8.82 99.20
80 INT140966 NFKB1 Positive_regulation of Positive_regulation of CPOX 1 0.08 0.66 0.8 99.20
81 INT128817 Ephb1 Negative_regulation of Gene_expression of Nos2 1 0.16 0.37 0.61 99.20
82 INT128814 Ephb1 Negative_regulation of Gene_expression of Il1b 1 0.02 0.37 0.61 99.20
83 INT125950 Syt17 Regulation of Trpv1 1 0.11 0.43 1.28 99.18
84 INT256296 Efnb1 Positive_regulation of Ephb1 1 0.03 0.66 0.54 99.16
85 INT145853 Casp1 Positive_regulation of Mapk14 1 0.02 0.68 0.93 99.14
86 INT90385 EXTL3 Regulation of Ctsl 1 0.00 1.1 0.98 99.12
87 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79 99.04
88 INT308172 Rvm Positive_regulation of Phosphorylation of GRIN1 1 0.50 0.68 1.14 99.04
89 INT68154 Mthfs Positive_regulation of Pdpk1 1 0.01 0.63 1.12 99.02
90 INT68158 Pla2g1b Positive_regulation of Pdpk1 1 0.05 0.63 1.12 99.02
91 INT68165 Alox5 Positive_regulation of Pdpk1 1 0.01 0.63 1.12 99.02
92 INT112961 NGF Positive_regulation of ICAM1 1 0.40 0.96 1.28 99.00
93 INT118812 Cck Positive_regulation of Rvm 1 0.21 0.65 1.46 98.96
94 INT262571 Phosphorylation of Trpv1 Positive_regulation of Localization of Calca 1 0.17 0.71 0.7 98.96
95 INT296484 Binding of Gria2 and GRIP1 1 0.04 4.52 4.59 98.92
96 INT182564 Binding of Ptger2 and Trpv1 1 0.18 1.77 2.67 98.88
97 INT335435 Ngf Positive_regulation of Ltb4r 1 0.52 1.06 1.16 98.88
98 INT128812 Mapk8 Negative_regulation of Gene_expression of Nos2 1 0.19 0.37 0.61 98.88
99 INT274948 Binding of Dh and Ltp 1 0.11 0.55 1.23 98.88
100 INT348380 Binding of Fdps and Lpar5 1 0.07 1.45 1.25 98.84
101 INT348396 Binding of LPAR5 and Fdps 1 0.07 0.81 0.69 98.84
102 INT139636 Jun Negative_regulation of Phosphorylation of Npy 1 0.33 1.07 1.01 98.84
103 INT139639 Jun Negative_regulation of Positive_regulation of Vip 1 0.53 1.07 1 98.84
104 INT139643 Jun Negative_regulation of Positive_regulation of Npy 1 0.33 1.07 1 98.84
105 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83 98.84
106 INT187805 Ms18 Regulation of Positive_regulation of Slc1a3 1 0.26 0.87 1.12 98.80
107 INT126019 Binding of Ltbr and Tnf 1 0.18 1.61 0.43 98.66
108 INT126020 Binding of fc and Tnf 1 0.22 1.61 0.43 98.66
109 INT126018 Binding of Lifr and Tnf 1 0.06 1.61 0.43 98.66
110 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51 98.64
111 INT78714 Ntrk1 Positive_regulation of Ngf 2 0.50 0.63 0.78 98.64
112 INT314213 Mapk14 Positive_regulation of Agtrap 1 0.04 1.15 1.34 98.64
113 INT148448 Inhbe Positive_regulation of Trpv1 1 0.08 0.7 0.67 98.60
114 INT338058 Par2 Positive_regulation of Positive_regulation of Trpv1 1 0.17 0.37 0.2 98.60
115 INT45306 Pomc Positive_regulation of ENG 2 0.07 1.11 1.68 98.52
116 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42 98.52
117 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1 98.48
118 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06 98.48
119 INT296950 Tacr1 Negative_regulation of Gene_expression of Cck 1 0.30 0.94 1.11 98.48
120 INT276863 Gpr65 Regulation of Trpv1 1 0.25 1.78 1.75 98.48
121 INT152113 Binding of NTSR1 and Ngf 3 0.33 2.09 2.62 98.44
122 INT119100 Positive_regulation of F2rl1 Positive_regulation of Positive_regulation of Ptgs1 1 0.03 0.56 0.9 98.44
123 INT143939 Il1b Regulation of Gene_expression of Fos 1 0.10 0.44 0.49 98.44
124 INT24967 Olr567 Regulation of Localization of Syt17 1 0.11 0.62 0.71 98.44
125 INT222243 Negative_regulation of Binding of Trpv1 and Ccr5 1 0.21 0.57 0.86 98.40
126 INT222244 Binding of Trpv1 and Ccr5 1 0.19 0.57 0.86 98.40
127 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97 98.38
128 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97 98.38
129 INT150632 Ea1 Negative_regulation of Mpo 1 0.17 1.55 2.9 98.32
130 INT165724 Bdkrb1 Positive_regulation of Adora1 1 0.24 1.65 0.43 98.28
131 INT256299 Binding of Efnb1 and Ephb1 1 0.02 1.22 1.42 98.24
132 INT249497 Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.02 0.51 0.54 98.24
133 INT339293 Casp1 Regulation of Localization of Il1 1 0.07 1.87 0.83 98.08
134 INT339290 Casp1 Regulation of Gene_expression of Il1 1 0.11 1.38 0.55 98.08
135 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11 98.04
136 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42 98.04
137 INT281085 Binding of Gria2 and Nsf 2 0.26 0.4 0.94 98.04
138 INT51225 Gal Regulation of Localization of Oxt 1 0.32 0.35 0.29 98.02
139 INT123387 Binding of Camk2a and Gria2 1 0.13 0.32 1.14 98.00
140 INT140890 Il10 Regulation of Il6 1 0.35 0.73 0.58 97.96
141 INT115272 Neu1 Positive_regulation of Coq10a 1 0.43 0.41 1.35 97.96
142 INT153534 Binding of Ephb1 and NMS 1 0.29 1.13 0.5 97.96
143 INT314214 Mapk14 Positive_regulation of Ngf 1 0.43 1.97 1.56 97.64
144 INT121727 Pik3cb Positive_regulation of Ephb1 1 0.49 0.6 1.06 97.64
145 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2 97.60
146 INT349658 Nos2 Regulation of Gene_expression of Nos1 1 0.63 2.86 1.84 97.60
147 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25 97.52
148 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79 97.52
149 INT261845 NGF Positive_regulation of Trpa1 1 0.04 0.73 0.71 97.52
150 INT96242 Il13 Negative_regulation of Gene_expression of Il1b 1 0.15 0.67 0.59 97.40
151 INT115271 Neu1 Positive_regulation of Coq10a 1 0.01 0.41 1.35 97.36
152 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22 97.32
153 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09 97.32
154 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.42 1.86 1.34 97.20
155 INT127876 ACE Positive_regulation of Protein_catabolism of CALCA 1 0.28 0.63 0.75 97.12
156 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2 97.12
157 INT128515 Binding of PNOC and Pnoc 1 0.12 0.38 1.14 97.08
158 INT109842 Prkce Positive_regulation of Localization of Trpv1 1 0.13 1.31 0.91 97.08
159 INT190130 Binding of CPOX and MRXS5 1 0.00 1.4 1.23 97.04
160 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22 96.96
161 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08 96.96
162 INT93690 Bdnf Regulation of Localization of Tacr1 1 0.10 0.28 0.61 96.96
163 INT90119 Ntrk2 Regulation of Gene_expression of Nfkb1 1 0.01 0.27 0.6 96.92
164 INT143938 Il1rn Negative_regulation of Il1b 1 0.04 0.52 0.57 96.88
165 INT143940 Il1rn Negative_regulation of Il1f5 1 0.00 0.51 0.57 96.88
166 INT352196 Igkv12-66 Negative_regulation of Gm10404 1 0.00 1.62 1.34 96.88
167 INT147653 TACR1 Positive_regulation of TRPV1 1 0.02 0.72 1.29 96.88
168 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92 96.88
169 INT308167 Binding of Eln and Tnfrsf1b 1 0.01 0.94 0.71 96.88
170 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 96.76
171 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91 96.76
172 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15 96.76
173 INT120319 Ghrh Regulation of Ngf 1 0.25 1.89 2.11 96.72
174 INT120317 Ghrh Regulation of Positive_regulation of Ngf 1 0.25 0.95 1.06 96.72
175 INT120311 Ghrh Regulation of Gene_expression of Ngf 1 0.25 0.95 1.06 96.72
176 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05 96.72
177 INT120316 Ghrh Regulation of Il6 1 0.11 0.95 1.05 96.72
178 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05 96.72
179 INT120310 Ghrh Regulation of Positive_regulation of Il6 1 0.18 0.95 1.05 96.72
180 INT256297 Binding of Creb1 and Insrr 1 0.00 1.22 1.19 96.72
181 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05 96.72
182 INT210696 Trpv1 Regulation of Slc12a2 1 0.25 1.97 2.58 96.64
183 INT90123 Jun Positive_regulation of Gene_expression of Fos 1 0.47 0.39 0.76 96.52
184 INT90122 Nfkb1 Positive_regulation of Gene_expression of Fos 1 0.39 0.39 0.75 96.52
185 INT121843 HLA-DRB5 Negative_regulation of Accn4 1 0.00 0.54 0.73 96.52
186 INT155406 Binding of Adrb2 and Ngf 1 0.05 0.39 0.53 96.48
187 INT335433 Cysltr2 Regulation of Trpv1 1 0.28 0.45 0.55 96.44
188 INT284785 Gch1 Regulation of Bh4p 1 0.00 1.48 1.54 96.40
189 INT148541 ST3GAL4 Positive_regulation of Positive_regulation of Trpv1 1 0.08 0.96 0.56 96.40
190 INT113743 Mc3r Regulation of Gene_expression of Agrp 1 0.05 0.9 0.98 96.36
191 INT86263 Binding of Tacr3 and Tac2 1 0.16 0.52 1.13 96.28
192 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57 96.20
193 INT314211 Ngf Positive_regulation of Gene_expression of Agtrap 1 0.04 1.15 1.3 96.20
194 INT314212 Mapk14 Positive_regulation of Gene_expression of Agtrap 1 0.06 1.09 1.24 96.20
195 INT169802 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Rapgef3 1 0.44 0.75 1.19 96.16
196 INT90118 Jun Regulation of Gene_expression of Nfkb1 1 0.18 0.39 0.76 96.16
197 INT212658 KCNA1 Positive_regulation of Cort 1 0.00 2.58 3.36 96.08
198 INT301138 Nsa2 Positive_regulation of Il10 1 0.03 1.22 0.39 96.08
199 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91 96.00
200 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19 95.92

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hyperalgesia. They are ordered first by their pain relevance and then by number of times they were reported in Hyperalgesia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 100.00
2 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 100.00
3 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 100.00
4 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 100.00
5 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 100.00
6 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03 100.00
7 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 100.00
8 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 100.00
9 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 100.00
10 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 100.00
11 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 100.00
12 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 100.00
13 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03 100.00
14 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 100.00
15 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
16 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 100.00
17 INT18992 Negative_regulation of Pdpk1 53 0.42 19.02 40.95 100.00
18 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19 100.00
19 INT47243 Gene_expression of Prkcg 195 0.78 58.05 108.44 100.00
20 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21 100.00
21 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66 100.00
22 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 100.00
23 INT2649 Regulation of Calca 433 0.62 146.05 330.95 100.00
24 INT90937 Negative_regulation of Gene_expression of Trpv1 34 0.59 22.74 18.12 100.00
25 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 100.00
26 INT12001 Regulation of Ngf 97 0.62 54.64 76.25 100.00
27 INT64261 Negative_regulation of Positive_regulation of Ngf 21 0.59 16.28 19.78 100.00
28 INT83602 Positive_regulation of Gene_expression of TRPV1 114 0.70 51.19 56.35 100.00
29 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01 100.00
30 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 100.00
31 INT19078 Binding of Ngf 78 0.48 31.03 44.33 100.00
32 INT5307 Regulation of Tnf 87 0.62 78.71 43.4 100.00
33 INT10706 Regulation of Il6 150 0.62 93.23 62.34 100.00
34 INT49922 Positive_regulation of Positive_regulation of Ngf 21 0.67 14.46 17.68 100.00
35 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45 100.00
36 INT12501 Positive_regulation of Adarb1 166 0.58 36.94 118.92 100.00
37 INT7134 Localization of KNG1 127 0.79 65.73 67.97 100.00
38 INT6864 Positive_regulation of Gene_expression of Gfap 110 0.70 59.01 47.07 100.00
39 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 100.00
40 INT27954 Positive_regulation of Gene_expression of Ngf 87 0.70 57.91 51.96 100.00
41 INT9347 Localization of Il1b 58 0.81 26.13 31.53 100.00
42 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 100.00
43 INT124881 Binding of Trpv4 35 0.47 7.71 6.24 100.00
44 INT1160 Positive_regulation of Rbm39 122 0.57 28.19 90.28 100.00
45 INT99069 Positive_regulation of Gene_expression of Mapk14 42 0.53 29.84 23.16 100.00
46 INT9299 Positive_regulation of Positive_regulation of Npr1 32 0.53 6.65 16.72 100.00
47 INT19527 Negative_regulation of Gene_expression of Il1a 26 0.51 15.4 11.58 100.00
48 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98 100.00
49 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66 100.00
50 INT11855 Positive_regulation of Gene_expression of Il1rl1 19 0.69 12.22 14.57 100.00
51 INT3076 Regulation of KNG1 52 0.60 20.39 27.89 100.00
52 INT118906 Regulation of Mapk14 21 0.44 17.95 11.63 100.00
53 INT5378 Regulation of Gene_expression of Fos 47 0.60 14.47 26.41 100.00
54 INT244386 Positive_regulation of Gene_expression of Slc12a2 10 0.58 18.39 4.5 100.00
55 INT96624 Positive_regulation of Positive_regulation of Trpv1 62 0.70 20.5 34.28 100.00
56 INT5948 Regulation of Il1b 44 0.60 22.8 25.4 100.00
57 INT53948 Regulation of Gene_expression of Cpox 40 0.51 20.97 13.87 100.00
58 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96 100.00
59 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43 100.00
60 INT103828 Negative_regulation of Gene_expression of TRPV1 23 0.59 13.63 13.81 100.00
61 INT3950 Gene_expression of Ptger2 293 0.77 122.28 62.42 100.00
62 INT177581 Regulation of Fig4 113 0.41 39.26 27.75 100.00
63 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 100.00
64 INT65772 Positive_regulation of Positive_regulation of Bdkrb1 6 0.49 8.34 6.54 100.00
65 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59 100.00
66 INT6867 Positive_regulation of Gene_expression of GFAP 22 0.67 13.46 9.75 100.00
67 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 100.00
68 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82 100.00
69 INT65907 Negative_regulation of Gene_expression of Ngf 36 0.59 19.5 20.03 100.00
70 INT68686 Gene_expression of Olr1869 5 0.39 2.3 3.21 100.00
71 INT9133 Negative_regulation of Positive_regulation of Prkcg 37 0.59 10.95 30.06 100.00
72 INT68744 Localization of Cxcl1 18 0.80 8.65 8.6 100.00
73 INT87432 Regulation of Gene_expression of Il1rl1 6 0.58 4.5 6.62 100.00
74 INT125411 Negative_regulation of Phosphorylation of Mapk14 31 0.57 18.55 19.98 100.00
75 INT60758 Gene_expression of Prkce 8 0.20 4.12 4.59 100.00
76 INT112174 Gene_expression of Trpv4 47 0.78 26.26 20.09 100.00
77 INT74545 Negative_regulation of Gene_expression of Prkcg 22 0.42 7.77 16.26 100.00
78 INT2828 Positive_regulation of Ptger3 26 0.68 8.01 9.63 100.00
79 INT39565 Gene_expression of Ptger2 424 0.75 229.28 72.68 100.00
80 INT22066 Gene_expression of Phax 40 0.78 22.51 25.91 100.00
81 INT48954 Positive_regulation of Localization of Il1b 13 0.53 8.16 6.44 100.00
82 INT48907 Positive_regulation of Gene_expression of Oprm1 53 0.69 8.55 33.52 100.00
83 INT55578 Regulation of Gene_expression of Il1b 7 0.62 4.74 5.55 100.00
84 INT38971 Positive_regulation of Gene_expression of Gtf3a 27 0.60 18.25 7.77 100.00
85 INT73155 Positive_regulation of Positive_regulation of Ngf 11 0.70 5.11 6.7 100.00
86 INT11894 Negative_regulation of Gene_expression of Ptger2 47 0.55 16.95 11.59 100.00
87 INT55035 Negative_regulation of Negative_regulation of Il1b 4 0.43 1.46 2.02 100.00
88 INT89805 Gene_expression of Prkaca 45 0.77 11.03 20.77 100.00
89 INT3030 Gene_expression of Adra2a 37 0.68 5.58 19.76 100.00
90 INT70848 Gene_expression of Casp1 24 0.77 10.97 8.52 100.00
91 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07 100.00
92 INT1414 Regulation of Oprl1 169 0.62 32.05 139.99 100.00
93 INT139130 Positive_regulation of Gene_expression of Slc12a5 8 0.51 4.43 4.33 100.00
94 INT62254 Negative_regulation of FLII 20 0.48 4.11 9.44 100.00
95 INT35029 Positive_regulation of Gene_expression of Ptger2 66 0.43 26.37 13.99 100.00
96 INT13823 Gene_expression of Egf 97 0.78 39.99 12.99 100.00
97 INT49553 Regulation of Gene_expression of Gfap 42 0.62 17.04 23.65 100.00
98 INT1682 Negative_regulation of Rem1 28 0.37 7.38 8.4 100.00
99 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49 100.00
100 INT48979 Regulation of Gene_expression of FOS 52 0.61 14.4 25.95 100.00
101 INT7506 Negative_regulation of Ltp 267 0.46 91.01 176.8 100.00
102 INT7553 Negative_regulation of Pih1d2 1 0.15 1.67 2.68 100.00
103 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6 100.00
104 INT65926 Positive_regulation of Gene_expression of Egf 26 0.70 12.91 4.18 100.00
105 INT73721 Negative_regulation of Gene_expression of Egf 5 0.43 2.28 1.8 100.00
106 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99 100.00
107 INT102865 Positive_regulation of Positive_regulation of Prkca 25 0.69 8.34 9.9 100.00
108 INT174844 Binding of Fig4 81 0.41 18.03 12.87 100.00
109 INT134379 Binding of Trpa1 13 0.48 7.16 7.27 100.00
110 INT15339 Regulation of Phax 8 0.45 4.34 6.49 100.00
111 INT63769 Regulation of Ngf 44 0.62 21.82 25.84 100.00
112 INT82284 Negative_regulation of Gene_expression of Arc 10 0.41 4.26 2.58 100.00
113 INT10536 Gene_expression of Trib3 67 0.66 27.08 21.58 100.00
114 INT60815 Binding of Bcl2l11 2 0.27 0.95 1.67 100.00
115 INT91013 Binding of IFNAR1 9 0.46 8.7 2.74 100.00
116 INT6913 Negative_regulation of Amelx 6 0.32 2.32 5.95 100.00
117 INT72612 Negative_regulation of Regulation of Pdyn 2 0.38 0.77 2.3 100.00
118 INT74557 Negative_regulation of Binding of Cnrip1 1 0.34 0.89 1.35 100.00
119 INT8532 Regulation of Transcription of PDYN 10 0.44 4.97 6.95 100.00
120 INT13276 Regulation of Ltp 107 0.53 30.78 69.13 100.00
121 INT76426 Positive_regulation of Negative_regulation of Cpox 18 0.35 6.84 9.95 100.00
122 INT4940 Negative_regulation of Localization of Tacr1 8 0.37 4.29 8.25 100.00
123 INT135332 Positive_regulation of Negative_regulation of Prkcc 1 0.46 0.74 1.75 100.00
124 INT135330 Positive_regulation of Negative_regulation of Plcb3 1 0.11 0.74 1.75 100.00
125 INT128185 Gene_expression of Prkce 4 0.69 1.39 2.23 100.00
126 INT133441 Negative_regulation of Positive_regulation of Rvm 2 0.28 3.01 3.51 100.00
127 INT62253 Regulation of Gene_expression of FLII 3 0.60 0.98 1.73 100.00
128 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76 100.00
129 INT134378 Binding of Trpm8 8 0.48 1.74 2.95 100.00
130 INT46833 Positive_regulation of SGSM3 56 0.67 24.49 30.31 100.00
131 INT241566 Negative_regulation of Negative_regulation of Calca 1 0.03 0.72 1.63 100.00
132 INT108780 Positive_regulation of Gene_expression of Ptger2 94 0.49 59.71 16.22 100.00
133 INT238709 Binding of PCBD1 1 0.34 2.37 1.41 100.00
134 INT115238 Positive_regulation of Gene_expression of Casp1 5 0.68 1.78 0.88 100.00
135 INT281645 Regulation of Gene_expression of Phax 3 0.08 2.51 2.44 100.00
136 INT35712 Regulation of Sdcbp 19 0.23 5.3 6.58 100.00
137 INT113736 Negative_regulation of Positive_regulation of Mc4r 1 0.08 1.11 0.93 100.00
138 INT59245 Localization of Pla2g1b 10 0.75 4.72 2.76 100.00
139 INT335363 Negative_regulation of Negative_regulation of Nmur2 1 0.18 2.31 1.44 100.00
140 INT75521 Positive_regulation of Positive_regulation of SGSM3 13 0.67 7.99 13.54 100.00
141 INT129496 Negative_regulation of Gene_expression of P2rx6 3 0.56 0.63 0.39 100.00
142 INT36726 Regulation of Gene_expression of Ltp 14 0.46 4.81 7.05 100.00
143 INT326657 Regulation of Binding of Ltp 1 0.09 2.26 1.36 100.00
144 INT10514 Negative_regulation of Gene_expression of Plat 8 0.47 6.22 2.24 100.00
145 INT47848 Negative_regulation of Positive_regulation of FOS 14 0.57 3.78 7.63 100.00
146 INT17333 Positive_regulation of Positive_regulation of FOS 17 0.67 6.06 8.4 100.00
147 INT71374 Positive_regulation of Gene_expression of Il12a 5 0.22 7.49 3.8 100.00
148 INT5854 Regulation of Gene_expression of Penk 22 0.61 6.91 10.03 100.00
149 INT8529 Regulation of Transcription of Penk 8 0.39 1.26 5.89 100.00
150 INT31874 Negative_regulation of Gene_expression of Abat 31 0.42 12.22 20.31 100.00
151 INT65226 Regulation of NARG2 3 0.36 1.6 1.99 100.00
152 INT76860 Gene_expression of HSPG2 32 0.65 37.14 9.06 100.00
153 INT75250 Negative_regulation of Positive_regulation of SGSM3 5 0.57 2.47 5.24 100.00
154 INT77429 Negative_regulation of Negative_regulation of CPOX 9 0.34 5.09 4.64 100.00
155 INT24671 Binding of FGF2 14 0.35 8.73 1.43 100.00
156 INT287730 Positive_regulation of Gene_expression of Tpnr1 1 0.01 1.43 1.08 100.00
157 INT50409 Regulation of Localization of Fos 3 0.44 0.2 1.07 100.00
158 INT95879 Regulation of Gene_expression of St13 2 0.33 1.02 0.57 100.00
159 INT128187 Gene_expression of RAPGEF3 1 0.65 0.53 0.38 100.00
160 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 99.98
161 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56 99.98
162 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24 99.98
163 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 99.98
164 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 99.98
165 INT118336 Positive_regulation of LOC682801 5 0.32 3.17 3.08 99.98
166 INT86751 Negative_regulation of Il10 62 0.59 40.1 20.51 99.98
167 INT68970 Positive_regulation of Pnoc 33 0.67 9.29 19.08 99.98
168 INT70539 Negative_regulation of Cxcl1 13 0.57 7.15 4.58 99.98
169 INT47876 Binding of Pnoc 20 0.47 4.99 20.01 99.98
170 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33 99.98
171 INT25503 Gene_expression of C5AR1 22 0.75 21.88 4.16 99.98
172 INT33218 Gene_expression of Csrp3 1 0.24 0.84 0.94 99.98
173 INT128745 Positive_regulation of Positive_regulation of Pik3cb 4 0.56 0.95 2.24 99.98
174 INT161080 Negative_regulation of asp3 1 0.23 1.28 1.03 99.98
175 INT79821 Negative_regulation of Binding of Pnoc 2 0.29 0.44 1.93 99.98
176 INT95785 Positive_regulation of Positive_regulation of Grm1 6 0.49 3.59 3.3 99.98
177 INT29055 Regulation of Positive_regulation of Ns5atp9 2 0.43 0.54 0.6 99.98
178 INT10174 Negative_regulation of Positive_regulation of Ns5atp9 4 0.40 1.41 0.66 99.98
179 INT10175 Positive_regulation of Ns5atp9 16 0.69 6.13 4.2 99.98
180 INT6067 Positive_regulation of Positive_regulation of Oprd1 37 0.69 6.56 36.58 99.98
181 INT148237 Positive_regulation of Tbpl1 4 0.49 2.05 1.59 99.98
182 INT10513 Gene_expression of Plat 44 0.76 19.49 7.17 99.98
183 INT105864 Binding of PRKG1 2 0.36 0.42 0.83 99.98
184 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 99.96
185 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51 99.96
186 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08 99.96
187 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 99.96
188 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 99.96
189 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 99.96
190 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75 99.96
191 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 99.96
192 INT10166 Localization of Tnf 237 0.81 153.95 88.64 99.96
193 INT121961 Positive_regulation of Gene_expression of Phospho1 2 0.15 2.8 3.57 99.96
194 INT112711 Gene_expression of Phospho1 11 0.21 5.65 8.34 99.96
195 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92 99.96
196 INT64440 Gene_expression of Pnoc 66 0.78 13.61 41.76 99.96
197 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57 99.96
198 INT23344 Gene_expression of Alox5 60 0.75 28.2 13.82 99.96
199 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68 99.96
200 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 99.96
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