D:Hypercalcemia

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Disease Term
Synonyms Bone Reabsorbtion, BONE REABSORPTION, Bone Readsorbtion, Bone Readsorption, BONE RESORBTION, Bone Resorption, Disorder Of Calcium Metabolism, Excessive Bone Resorbtion, EXCESSIVE BONE RESORPTION, Familial Hypocalciuric Hypercalcaemia, Familial Hypocalciuric Hypercalcemia
Documents 2579
Hot Single Events 200
Hot Interactions 127

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hypercalcemia. They are ordered first by their relevance to Hypercalcemia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11 100.00
2 INT187229 Binding of Tnfsf11 and Insrr 1 0.00 2.06 0.78 100.00
3 INT187231 Negative_regulation of Binding of Tnfrsf11a and Tnfsf11 1 0.18 1.8 0.71 100.00
4 INT89475 TGFB1 Positive_regulation of Gene_expression of PTHLH 3 0.61 3.64 0.21 100.00
5 INT289252 Il6 Negative_regulation of Tnfrsf11a 1 0.11 0.82 0.04 100.00
6 INT212013 RAD51D Negative_regulation of ALPP 1 0.00 0.7 0 100.00
7 INT196592 Binding of CFD and GHRH 1 0.02 1.88 0.07 100.00
8 INT340273 Fig4 Regulation of BGLAP 1 0.00 0.55 0.04 99.96
9 INT188801 Il6 Positive_regulation of Positive_regulation of Tnfsf11 1 0.06 0.46 0.21 99.92
10 INT199159 Binding of RET and Pheo 1 0.04 1.42 0.03 99.68
11 INT139782 PRSS53 Negative_regulation of Positive_regulation of ASNA1 1 0.01 0.91 0.11 99.64
12 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3 99.44
13 INT148531 Binding of TNFRSF11A and Tnfsf11 2 0.08 1.77 0.17 99.08
14 INT146806 Tnfrsf11b Positive_regulation of Pth 1 0.46 1.43 0 99.04
15 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27 99.04
16 INT269759 PTH Positive_regulation of DMD 2 0.06 0.37 0.03 98.96
17 INT301279 Tnfsf11 Regulation of Gene_expression of Mmp9 1 0.13 0.34 0.21 98.96
18 INT301281 Tnfsf11 Regulation of Gene_expression of Clec5a 1 0.22 0.34 0.21 98.96
19 INT254281 Il4 Negative_regulation of Gene_expression of Acp5 1 0.02 0.41 0.22 98.88
20 INT345190 Lpar1 Regulation of Localization of Il6 1 0.05 1.19 0.04 98.88
21 INT301292 Negative_regulation of Clec5a Negative_regulation of TNF 1 0.05 1.04 0.27 98.80
22 INT181998 TNFRSF11B Negative_regulation of Gene_expression of CTSK 1 0.07 1.98 0.27 98.80
23 INT311264 IL6 Positive_regulation of Gene_expression of PPIAP10 1 0.30 0.98 0.36 98.80
24 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91 98.80
25 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95 98.80
26 INT188803 Il1 Positive_regulation of Gene_expression of Crp 1 0.03 2.95 0.94 98.80
27 INT133307 Binding of CD44 and SPP1 5 0.26 2.6 0.35 98.70
28 INT186685 Edn1 Regulation of Gene_expression of Il6 1 0.11 1.1 0 98.64
29 INT210598 PTHLH Positive_regulation of Gene_expression of TNFSF11 1 0.23 0.98 0.04 98.48
30 INT196525 Binding of MMP2 and MMP9 2 0.32 2.49 0.78 98.28
31 INT266834 Pth Negative_regulation of Positive_regulation of Grxcr1 1 0.04 0.51 0 98.28
32 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41 98.16
33 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09 98.16
34 INT307225 CYLD Regulation of TNFRSF11A 1 0.14 0.81 0 98.04
35 INT264300 CTSK Positive_regulation of CYP27A1 1 0.03 0.69 0.07 97.92
36 INT352547 Binding of CFTR and DMD 1 0.01 1.42 0.35 97.60
37 INT329479 Binding of TNFRSF11B and TNF 1 0.04 0.71 0 97.32
38 INT329480 Binding of TNFRSF11B and TNFSF10 1 0.03 0.71 0 97.32
39 INT320810 Protein_catabolism of COL1A2 Positive_regulation of Localization of CYP27A1 1 0.04 1.05 0.4 97.24
40 INT301289 Positive_regulation of Clec5a Positive_regulation of Gene_expression of Atp6v0d2 1 0.02 1.01 0.28 97.20
41 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 97.04
42 INT178578 Binding of PTHLH and CALCRL 1 0.01 0.68 0.27 96.88
43 INT107910 Binding of Tnfrsf11b and Tnfsf11 6 0.30 5.88 0.7 96.80
44 INT172125 Binding of Tnfrsf11b and Tnfrsf11a 2 0.17 2.12 0.39 96.80
45 INT277832 Binding of TNFRSF1B and NPEPPS 1 0.01 1.1 0.88 96.12
46 INT277831 Binding of TNFRSF1A and NPEPPS 1 0.01 1.1 0.87 96.12
47 INT355364 Regulation of PTHLH Positive_regulation of Tnfsf11 1 0.04 1.51 0.19 95.80
48 INT355363 PTHLH Positive_regulation of Tnfsf11 1 0.04 1.47 0.19 95.80
49 INT314369 Tnfsf11 Negative_regulation of Gene_expression of Tnfrsf11b 1 0.08 2.2 0.05 95.76
50 INT289245 Binding of Il6ra and Positive_regulation of Gene_expression of Ptger2 1 0.00 0.82 0.15 95.72
51 INT355366 Regulation of CSF1 Positive_regulation of Tnfsf11 1 0.02 1.5 0.19 95.12
52 INT355365 CSF1 Positive_regulation of Tnfsf11 1 0.03 1.49 0.19 95.12
53 INT197649 NR1I2 Positive_regulation of VDR 1 0.15 0.54 0.07 94.88
54 INT197648 ESRRB Positive_regulation of VDR 1 0.03 0.54 0.07 94.88
55 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85 94.84
56 INT180570 Binding of HEYL and Positive_regulation of DMD 1 0.00 1.08 0.28 94.44
57 INT264327 IL-17 Positive_regulation of Gene_expression of Tnfsf11 1 0.07 3.19 1.33 94.24
58 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 94.20
59 INT156517 Binding of CNR1 and FAAH 3 0.38 1.53 0.53 94.20
60 INT156519 Binding of CNR1 and NAPEPLD 1 0.39 0.19 0.4 94.20
61 INT156521 Binding of CNR2 and FAAH 1 0.38 0.19 0.46 94.04
62 INT156520 Binding of CNR2 and NAPEPLD 1 0.39 0.19 0.4 94.04
63 INT139790 PRSS53 Negative_regulation of Phosphorylation of NFKBIA 1 0.01 0.9 0.11 93.96
64 INT139784 PRSS53 Negative_regulation of Positive_regulation of NFKB1 1 0.09 0.9 0.11 93.96
65 INT156518 Binding of FAAH and NAPEPLD 1 0.38 0.19 0.46 93.88
66 INT224423 Binding of TNFRSF11B and TNFRSF11A 3 0.19 2.36 0.37 93.84
67 INT182804 Binding of ETV3 and T2DM 1 0.10 2.62 0 93.44
68 INT139787 Negative_regulation of TNFAIP8 Positive_regulation of IKBKG 1 0.10 0.89 0.11 93.16
69 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 93.12
70 INT139783 TNFAIP8 Positive_regulation of IKBKG 1 0.12 0.88 0.11 92.72
71 INT139786 TNFAIP8 Positive_regulation of Phosphorylation of IKBKG 1 0.12 0.89 0.11 92.72
72 INT139789 TNFAIP8 Positive_regulation of Phosphorylation of NFKBIA 1 0.02 0.89 0.11 92.72
73 INT139788 TNFAIP8 Positive_regulation of NFKBIA 1 0.01 0.88 0.11 92.72
74 INT139792 TNFAIP8 Positive_regulation of Protein_catabolism of IKBKG 1 0.12 0.89 0.11 92.72
75 INT139785 TNFAIP8 Positive_regulation of Positive_regulation of NFKB1 1 0.19 0.89 0.11 92.72
76 INT289247 Ptger2 Positive_regulation of Gene_expression of Tnfrsf11a 1 0.00 0.76 0.14 92.60
77 INT186672 IL8 Positive_regulation of Transcription of PTH 1 0.01 1.83 0.85 91.36
78 INT186673 IL8 Positive_regulation of Positive_regulation of PTH 1 0.01 0.92 0.42 91.36
79 INT289249 Il6 Regulation of Gene_expression of Ptger2 1 0.01 0.77 0.1 91.28
80 INT165766 Tnfsf11 Negative_regulation of Tnfsf11 Positive_regulation of Nfkb1 1 0.00 1.08 0.33 91.28
81 INT299789 IL4 Negative_regulation of Gene_expression of RAE1 1 0.00 0.84 0.41 91.24
82 INT299786 IL4 Negative_regulation of Gene_expression of CD5 1 0.07 0.82 0.4 91.24
83 INT330976 Igh-Dex Positive_regulation of Gene_expression of VDR 1 0.01 1.11 0.23 91.08
84 INT165763 Tnfsf11 Positive_regulation of Phosphorylation of Mapk3 1 0.40 1.08 0.33 90.84
85 INT165764 Tnfsf11 Positive_regulation of Mapk3 1 0.17 1.08 0.33 90.84
86 INT165765 Tnfsf11 Positive_regulation of Nfkb1 1 0.01 1.07 0.33 90.84
87 INT352555 DKK1 Positive_regulation of Wnt2 1 0.01 0.25 0.1 89.88
88 INT314370 Adipoq Positive_regulation of Tnfrsf11a 1 0.04 1.26 0.03 89.84
89 INT166724 Binding of Vdr and Rxra 1 0.28 0.32 0.09 89.80
90 INT210597 Negative_regulation of Binding of TNFSF11 and TNFRSF11A 3 0.26 5.66 0.33 88.72
91 INT166723 Binding of Vdr and Rxrb 1 0.11 0.31 0.09 88.72
92 INT267627 Il1 Positive_regulation of Gene_expression of TNF 1 0.02 0.45 0.17 88.72
93 INT209444 Stam Positive_regulation of Syk 1 0.01 0.26 0 88.40
94 INT124412 Binding of PTH and Pth 1 0.02 0.65 0.14 88.08
95 INT295006 Binding of TNFRSF11A and Tnfrsf11b 2 0.10 1.6 0.04 88.00
96 INT295005 Binding of TNFRSF11A and Tnfsf11 3 0.20 2.02 0.09 88.00
97 INT270777 Binding of DMD and BPs 1 0.01 0.33 0.09 88.00
98 INT295003 Binding of Tnfrsf11b and Tnfsf11 3 0.22 1.85 0.08 87.80
99 INT201512 Binding of PRSS1 and hcp 1 0.09 1.9 0.57 87.48
100 INT264333 IL-17 Positive_regulation of Gene_expression of Mmp1a 1 0.05 2.88 1.18 87.04
101 INT254280 Il4 Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.79 0.54 86.40
102 INT254279 Il13 Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.79 0.54 86.04
103 INT56134 CALCA Positive_regulation of POMC 2 0.71 0.72 1.68 86.00
104 INT173558 CTSK Positive_regulation of Protein_catabolism of COL5A2 1 0.00 0.53 0.22 85.76
105 INT180564 HEYL Regulation of Regulation of DMD 1 0.00 0.88 0.28 85.68
106 INT210593 TNFRSF11B Negative_regulation of Binding of TNFSF11 and TNFRSF11A 2 0.10 1.62 0.04 84.96
107 INT210596 TNFRSF11B Negative_regulation of Binding of TNFSF11 2 0.11 1.62 0.04 84.96
108 INT181997 TNFRSF11B Negative_regulation of CTSK 1 0.05 0.58 0.14 84.92
109 INT135180 IL1B Positive_regulation of Gene_expression of TNFSF11 2 0.76 1.73 0.75 84.08
110 INT197644 NR1I2 Negative_regulation of Positive_regulation of CYP3A 1 0.02 0.47 0.08 83.32
111 INT197650 NR1I2 Negative_regulation of Positive_regulation of CYP2A 1 0.02 0.47 0.08 83.32
112 INT197652 NR1I2 Positive_regulation of Positive_regulation of CYP2A 1 0.02 0.47 0.08 83.32
113 INT197646 DPH1 Negative_regulation of Localization of BGLAP 1 0.01 0.26 0.04 83.12
114 INT257577 CALCA Positive_regulation of DMD 1 0.01 0.57 0.26 82.80
115 INT254278 Binding of Il13 and Il4 1 0.02 0.74 0.38 82.40
116 INT215035 Trh Positive_regulation of Gh 1 0.07 0.89 0 82.36
117 INT270121 Binding of Pth and Pthlh 1 0.08 0.56 0 82.32
118 INT301276 Il6 Positive_regulation of Gene_expression of Tnfrsf11a 1 0.06 0.37 0.26 82.00
119 INT301280 Il6 Positive_regulation of Gene_expression of Acp5 1 0.04 0.37 0.26 82.00
120 INT301291 Il6 Positive_regulation of Gene_expression of TNF 1 0.01 0.37 0.26 82.00
121 INT172144 IL4 Negative_regulation of Transcription of PLA2G4A 1 0.02 0.82 0.58 81.76
122 INT88937 Mmv7 Regulation of Gene_expression of SPP1 1 0.00 1.24 0.12 81.56
123 INT299790 IL4 Negative_regulation of Gene_expression of NPEPPS 1 0.00 0.86 0.37 81.28
124 INT299788 INCENP Negative_regulation of Gene_expression of NPEPPS 1 0.00 0.86 0.37 81.28
125 INT266833 Phex Regulation of Gene_expression of Fgf23 1 0.23 0.46 0 81.24
126 INT197651 TNF Regulation of PTH 1 0.05 1.67 0 80.28
127 INT197643 TNF Regulation of VDR 1 0.04 1.67 0 80.28
128 INT301277 Il6 Positive_regulation of Positive_regulation of Clec5a 1 0.16 0.37 0.29 79.84
129 INT205158 Gene_expression of SPP1 Positive_regulation of Gene_expression of TNFSF11 1 0.11 1.08 0.08 79.72
130 INT25354 Chi3l1 Negative_regulation of Ptgs1 1 0.00 0.39 0.34 79.44
131 INT172133 IL4 Negative_regulation of Gene_expression of HMOX2 1 0.00 0.81 0.58 79.28
132 INT264298 NOL3 Negative_regulation of CRP 1 0.39 0.49 0.2 79.20
133 INT301278 Nfatc1 Regulation of Acp5 1 0.05 0.19 0.15 78.52
134 INT56132 CALCA Positive_regulation of Localization of POMC 1 0.51 0.16 0.44 78.20
135 INT301283 Nfatc1 Regulation of Ctsk 1 0.06 0.19 0.13 78.16
136 INT181996 TNFRSF11B Positive_regulation of Gene_expression of TIMP1 1 0.00 0.67 0.18 78.08
137 INT213392 Binding of SELPLG and XPO1 1 0.02 0.31 0.04 77.20
138 INT334043 Cdt1 Positive_regulation of Gene_expression of ALPP 1 0.08 0.39 0.05 76.48
139 INT266837 Dmp1 Negative_regulation of Gene_expression of Fgf23 1 0.48 2.41 0 76.08
140 INT58630 Calca Negative_regulation of Positive_regulation of COL1A1 1 0.02 0.23 0.08 76.04
141 INT264338 Binding of IL-17 and Positive_regulation of Localization of TNF 1 0.04 1.71 0.67 76.00
142 INT215978 Binding of HPT and Pth 1 0.01 0.92 0 75.96
143 INT270134 BPs Negative_regulation of FDPS 1 0.01 0.36 0.05 75.68
144 INT174532 PTH Positive_regulation of Transcription of IGF1 1 0.06 0.51 0 75.64
145 INT223482 CRP Positive_regulation of GOPC 1 0.08 0.8 0.1 75.60
146 INT172141 IL10 Negative_regulation of Gene_expression of HLA-DRA 2 0.14 0.89 1.23 75.04
147 INT172145 IL10 Negative_regulation of Gene_expression of CSF2 1 0.04 0.69 0.59 75.04
148 INT16163 Pth Regulation of Gene_expression of Plast4 1 0.00 0.65 0.25 75.00
149 INT295007 Binding of DMD and Pth 1 0.00 0.07 0 74.92
150 INT209884 Binding of IL4 and TNF 1 0.04 0.73 0.26 74.68
151 INT224584 Binding of IL1RN and SIGMAR1 1 0.00 0.73 0.36 74.44
152 INT187225 Vip Negative_regulation of Gene_expression of Tnfrsf11a 1 0.27 1.92 0.87 74.36
153 INT264329 Binding of IL-17 and Positive_regulation of Localization of Ccl2 1 0.13 1.65 0.64 74.16
154 INT188802 Il1 Negative_regulation of Gene_expression of Col7a1 1 0.00 0.71 0.26 73.92
155 INT330955 HOMER1 Positive_regulation of Gene_expression of VDR 1 0.01 0.99 0.08 73.72
156 INT27759 Calca Regulation of Sct 1 0.00 0.9 0.08 73.52
157 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 73.48
158 INT264295 Binding of DMD and IGF1 1 0.07 1.38 0.44 73.44
159 INT209879 CSF2 Positive_regulation of Gene_expression of TNFRSF11B 1 0.10 0.76 0.26 73.40
160 INT217486 Binding of PDB1 and Sqstm1 1 0.03 1.19 0.08 73.24
161 INT314374 Binding of Ptprc and Thy1 1 0.04 0.85 0 72.68
162 INT314371 Binding of Cd34 and Thy1 1 0.08 0.9 0 72.68
163 INT314373 Binding of Cd34 and Eng 1 0.08 0.9 0 72.32
164 INT314372 Binding of Eng and Ptprc 1 0.04 0.84 0 72.32
165 INT301288 Clec5a Regulation of Nfatc1 1 0.21 0.25 0.1 72.04
166 INT339778 Binding of EDNRA and PTH 1 0.12 0.35 0.05 71.92
167 INT264334 Binding of IL-17 and Positive_regulation of Localization of Csf3 1 0.13 1.64 0.63 71.60
168 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36 70.92
169 INT175553 Binding of CASR and CP 1 0.11 1.65 1.03 70.72
170 INT269061 Binding of Il6 and Il6ra 3 0.04 2.59 0.45 70.48
171 INT175552 Binding of CASR and UPF1 1 0.01 0.89 0.33 70.16
172 INT280270 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.08 1.81 0.19 70.00
173 INT280268 Tgfb1 Positive_regulation of Gene_expression of Vegfa 1 0.06 1.81 0.19 70.00
174 INT280261 Tgfb1 Positive_regulation of Gene_expression of Cxcr1 1 0.05 1.81 0.19 70.00
175 INT280274 Tgfb1 Positive_regulation of Gene_expression of VEGFA 1 0.02 2.58 0.19 70.00
176 INT340277 Tnfsf11 Positive_regulation of TRAP 1 0.03 0.76 0 69.88
177 INT340238 Tnfsf11 Positive_regulation of Gene_expression of Fig4 1 0.02 0.4 0 69.88
178 INT257590 Pth Positive_regulation of DMD 2 0.02 0.44 0 69.84
179 INT280266 Tgfb1 Positive_regulation of Vegfa 1 0.09 1.8 0.19 69.80
180 INT280275 Tgfb1 Positive_regulation of VEGFA 1 0.02 2.46 0.19 68.36
181 INT293408 HRAS Regulation of VEGFA 1 0.00 1.18 0.1 68.32
182 INT293409 IL8 Regulation of VEGFA 1 0.04 1.18 0.1 68.32
183 INT293416 IL8 Regulation of PTHLH 1 0.04 1.18 0.1 68.08
184 INT293414 HRAS Regulation of PTHLH 1 0.00 1.18 0.1 68.08
185 INT264335 Binding of IL-17 and Positive_regulation of Localization of Il6 1 0.13 1.62 0.62 68.00
186 INT280260 Tgfb1 Positive_regulation of Cxcr1 1 0.07 1.78 0.19 67.80
187 INT293411 IL8 Regulation of IL11 1 0.03 1.17 0.1 67.64
188 INT293417 HRAS Regulation of IL11 1 0.00 1.17 0.1 67.64
189 INT321891 Dkk1 Negative_regulation of Wnt2 1 0.12 0.94 0.05 67.36
190 INT301284 Tnfsf11 Positive_regulation of Localization of Nfatc1 1 0.16 0.32 0.11 66.96
191 INT188804 S100a8 Positive_regulation of Gene_expression of Tnfsf11 1 0.00 0.7 0.31 66.84
192 INT280267 Tgfb1 Positive_regulation of Cxcr4 1 0.11 2.45 0.19 66.76
193 INT93535 PTH Negative_regulation of Gene_expression of Tnfsf11 1 0.19 0.22 0.11 66.72
194 INT209880 IL4 Regulation of Gene_expression of TNFRSF11B 1 0.09 0.74 0.23 66.52
195 INT180961 Binding of MOCS1 and PLAU 1 0.00 0.61 0.67 66.40
196 INT338999 Binding of BTF3P11 and Tnfsf11 1 0.01 0.35 0.08 66.20
197 INT341666 ALPI Positive_regulation of ENPEP 1 0.01 1.05 0 65.92
198 INT203166 Negative_regulation of CPOX Positive_regulation of Gene_expression of LTB4R 1 0.00 0.65 0.34 65.72
199 INT183750 Binding of EPO and TF 1 0.42 1.21 0 65.12
200 INT187230 Binding of Adcyap1 and Vipr1 1 0.11 0.92 0.38 64.88

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hypercalcemia. They are ordered first by their pain relevance and then by number of times they were reported in Hypercalcemia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT6512 Gene_expression of PTH 103 0.77 76.29 6.33 100.00
2 INT17701 Gene_expression of PTHLH 103 0.78 64.23 8.85 100.00
3 INT175555 Gene_expression of CASR 17 0.78 14.83 3.73 100.00
4 INT22715 Positive_regulation of Gene_expression of Pth 29 0.64 22.53 2.31 100.00
5 INT106127 Negative_regulation of CASR 7 0.43 7.12 0.67 100.00
6 INT6514 Positive_regulation of Gene_expression of PTH 28 0.67 30.28 1.37 100.00
7 INT172551 Negative_regulation of INCENP 38 0.07 20.83 3.14 100.00
8 INT119729 Binding of Tnfsf11 31 0.35 24.02 7.45 100.00
9 INT53184 Negative_regulation of CYP27A1 46 0.57 16.04 5.28 100.00
10 INT173808 Positive_regulation of CYP27A1 35 0.68 23.7 7.87 100.00
11 INT79299 Negative_regulation of NXT1 16 0.32 8.27 3.78 100.00
12 INT197842 Gene_expression of PHPT1 1 0.06 5.89 0.16 100.00
13 INT114824 Binding of PTHLH 12 0.42 9.5 0.9 100.00
14 INT61102 Gene_expression of MEN1 12 0.78 17.7 0.43 100.00
15 INT175558 Positive_regulation of CASR 5 0.47 3.55 0.6 100.00
16 INT39500 Positive_regulation of Positive_regulation of Pth 14 0.48 9.75 1.28 100.00
17 INT110599 Gene_expression of Bglap 49 0.74 41.23 6.97 100.00
18 INT90655 Negative_regulation of Hpt 3 0.37 3.24 1.72 100.00
19 INT19131 Localization of CYP27A1 14 0.80 8.19 2.15 100.00
20 INT61684 Localization of COL1A2 20 0.73 9.31 2.26 100.00
21 INT197828 Negative_regulation of MEN1 1 0.43 5.06 0.06 100.00
22 INT153794 Gene_expression of Ctsk 51 0.77 24.99 7.28 100.00
23 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 100.00
24 INT197835 Positive_regulation of Gene_expression of PHPT1 1 0.04 3.17 0.07 100.00
25 INT197836 Positive_regulation of Gene_expression of MEN1 1 0.50 3.16 0.07 100.00
26 INT197839 Negative_regulation of PHPT1 1 0.04 2.88 0.06 100.00
27 INT61465 Gene_expression of Acp5 22 0.75 7.06 2.55 100.00
28 INT197827 Regulation of PHPT1 1 0.03 2.54 0.08 100.00
29 INT124963 Positive_regulation of HRPT1 1 0.00 1 0.09 100.00
30 INT62669 Positive_regulation of COL1A2 13 0.49 6.89 1.4 100.00
31 INT36479 Binding of NR0B2 2 0.36 3.5 0.21 100.00
32 INT266786 Binding of ASAH1 2 0.11 3.87 0.44 100.00
33 INT87988 Gene_expression of ASAH1 9 0.77 9.75 1.18 100.00
34 INT229301 Gene_expression of NR0B2 3 0.18 3.49 0.16 100.00
35 INT64801 Negative_regulation of RUVBL1 2 0.37 1.3 0.43 100.00
36 INT9500 Negative_regulation of Ceacam1 26 0.58 6.89 3.91 100.00
37 INT90654 Binding of Hpt 2 0.40 2.37 0.38 100.00
38 INT266832 Positive_regulation of Grxcr1 9 0.12 7.91 0.19 100.00
39 INT269764 Positive_regulation of Localization of CYP27A1 4 0.38 2.45 0.8 100.00
40 INT129832 Positive_regulation of Positive_regulation of PTH 5 0.50 3.4 0.14 100.00
41 INT114081 Positive_regulation of Hpt 4 0.18 1.41 0.09 100.00
42 INT146804 Positive_regulation of Gene_expression of Acp5 3 0.12 3.21 0.28 100.00
43 INT219876 Positive_regulation of PHPT1 1 0.01 1.25 0 100.00
44 INT115423 Gene_expression of Men1 4 0.47 14.08 0.64 100.00
45 INT132717 Localization of PAX5 3 0.50 1.27 0.03 100.00
46 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6 100.00
47 INT257885 Negative_regulation of Positive_regulation of CYP27A1 2 0.37 1.62 0.57 100.00
48 INT2541 Binding of Calca 200 0.48 67.14 134.62 100.00
49 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23 100.00
50 INT18406 Regulation of Regulation of GHRH 2 0.45 0.93 0.76 100.00
51 INT92311 Regulation of SIL1 7 0.44 6.2 1.61 100.00
52 INT114842 Localization of RET 3 0.71 5.98 0.71 100.00
53 INT22081 Regulation of Ceacam1 8 0.23 4.11 0.95 100.00
54 INT19086 Negative_regulation of COL1A1 32 0.38 16.77 5.98 100.00
55 INT54895 Binding of Epo 24 0.48 11.38 4.48 100.00
56 INT9210 Regulation of IL6 166 0.62 125.61 49.95 100.00
57 INT212025 Localization of RAD51D 1 0.08 1.29 0 100.00
58 INT209428 Positive_regulation of Tyrobp 2 0.44 0.79 0.4 100.00
59 INT10706 Regulation of Il6 150 0.62 93.23 62.34 100.00
60 INT22454 Regulation of Crp 213 0.62 160.67 49.24 100.00
61 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 100.00
62 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 100.00
63 INT19492 Regulation of B2M 16 0.60 10.97 2.55 100.00
64 INT224620 Positive_regulation of Gene_expression of Ctsk 13 0.68 8.35 2.21 100.00
65 INT48903 Protein_catabolism of ACE2 1 0.08 1.13 0.66 100.00
66 INT97305 Positive_regulation of Binding of COL1A2 1 0.49 0.27 0.1 100.00
67 INT184302 Regulation of Llph 1 0.01 0.56 0.09 100.00
68 INT280235 Localization of Me2 1 0.01 1.67 0 100.00
69 INT12081 Localization of TGFB1 64 0.81 35.4 17.47 99.98
70 INT172559 Localization of Proc 16 0.02 21.49 2.08 99.98
71 INT126726 Binding of Pthlh 1 0.03 1.05 0.09 99.98
72 INT34777 Localization of IGF1 82 0.80 42.68 8.62 99.98
73 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 99.96
74 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66 99.96
75 INT17250 Negative_regulation of BGLAP 35 0.57 21 8.26 99.96
76 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 99.96
77 INT240280 Gene_expression of IGFALS 14 0.42 20.38 0.95 99.96
78 INT117172 Regulation of Hpt 7 0.41 3.39 0.52 99.96
79 INT133316 Localization of CTSK 5 0.52 2.43 0.43 99.96
80 INT4864 Regulation of BGLAP 22 0.34 10.8 5.07 99.96
81 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92 99.96
82 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 99.96
83 INT140257 Binding of Llph 2 0.01 3.54 0.96 99.96
84 INT48902 Gene_expression of ACE2 22 0.78 17.91 3.24 99.96
85 INT320985 Positive_regulation of Localization of Pth 1 0.37 1.26 0.08 99.96
86 INT59083 Positive_regulation of Gene_expression of IL1A 11 0.70 9.09 4.48 99.96
87 INT166881 Positive_regulation of Ccr1 31 0.69 18.14 7.9 99.96
88 INT153268 Positive_regulation of Ccr5 25 0.66 19 7.02 99.96
89 INT11551 Localization of VHL 12 0.65 22.76 0.68 99.94
90 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 99.92
91 INT173576 Negative_regulation of FDPS 25 0.57 8.42 1.91 99.92
92 INT123701 Negative_regulation of VDR 61 0.59 48.94 9.67 99.92
93 INT224429 Regulation of TNFSF11 8 0.61 4.35 1.13 99.92
94 INT173578 Negative_regulation of CTSK 8 0.44 6.29 1.15 99.92
95 INT224424 Regulation of TNFRSF11B 12 0.61 6.29 1.61 99.92
96 INT162057 Negative_regulation of TNFSF11 14 0.58 9.78 1.46 99.92
97 INT4342 Localization of ALPP 27 0.69 15.19 5.32 99.92
98 INT129960 Negative_regulation of Gene_expression of MMP13 19 0.53 7.17 3.55 99.92
99 INT194876 Negative_regulation of Gene_expression of CTSK 1 0.03 0.75 0.23 99.92
100 INT143923 Regulation of Positive_regulation of COL1A2 1 0.02 0.86 0.2 99.92
101 INT124355 Negative_regulation of BEST1 11 0.19 6.13 2.04 99.92
102 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 99.90
103 INT13416 Positive_regulation of Pthlh 19 0.60 14.78 3.74 99.90
104 INT62071 Positive_regulation of Gene_expression of PTHLH 13 0.70 19.32 1.73 99.90
105 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.90
106 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 99.90
107 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 99.90
108 INT2244 Positive_regulation of Localization of GAST 7 0.68 5.28 0.73 99.90
109 INT80452 Positive_regulation of Gene_expression of Pthlh 4 0.40 3.77 0.62 99.90
110 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 99.90
111 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34 99.90
112 INT293420 Positive_regulation of Localization of IL11 4 0.37 1.55 0.03 99.90
113 INT192686 Positive_regulation of Positive_regulation of DMD 8 0.41 4.66 0.93 99.88
114 INT110427 Gene_expression of Spp1 199 0.78 176.11 23.31 99.88
115 INT225251 Negative_regulation of S100a7a 1 0.12 8.91 0.43 99.88
116 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 99.88
117 INT62360 Positive_regulation of PTHLH 31 0.70 28.23 3.46 99.86
118 INT12243 Positive_regulation of PRSS1 91 0.70 52.87 19.48 99.86
119 INT22782 Localization of PRSS1 25 0.81 14.44 7.34 99.86
120 INT200218 Localization of SDHD 1 0.69 48.58 4.57 99.86
121 INT53927 Positive_regulation of Localization of PTH 8 0.69 5.33 0.09 99.86
122 INT19132 Gene_expression of CYP27A1 83 0.75 34.31 10.17 99.84
123 INT19395 Negative_regulation of Localization of Pth 11 0.58 10.16 0.55 99.84
124 INT93532 Regulation of Tnfsf11 14 0.42 10.75 2.39 99.84
125 INT55962 Positive_regulation of Localization of PROC 9 0.20 7.76 1.87 99.84
126 INT95669 Regulation of TNFRSF11A 7 0.56 10.01 0.94 99.84
127 INT320811 Negative_regulation of GLP2R 1 0.04 0.99 0.06 99.84
128 INT153773 Regulation of Gene_expression of CTSK 2 0.34 1.36 0.62 99.84
129 INT626 Localization of CALCA 289 0.81 125.39 221.15 99.84
130 INT3521 Regulation of Csf2 38 0.54 11.09 12.73 99.84
131 INT182004 Regulation of Localization of CTSK 1 0.20 0.58 0.18 99.84
132 INT250 Regulation of GHRH 65 0.61 17.46 23.19 99.84
133 INT6625 Negative_regulation of Pth 96 0.58 57.6 8.24 99.82
134 INT4535 Localization of PROC 106 0.73 76.24 21.1 99.82
135 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 99.80
136 INT285 Positive_regulation of Salpa1 73 0.68 61.47 9.19 99.80
137 INT125479 Positive_regulation of HHIP 38 0.44 12.39 3.75 99.80
138 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 99.80
139 INT102659 Gene_expression of CSF3 32 0.77 21.93 2.39 99.80
140 INT32515 Negative_regulation of B4GALNT1 82 0.43 28.1 17.46 99.80
141 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 99.80
142 INT25122 Binding of PTGER2 31 0.31 13.83 3.12 99.80
143 INT102658 Negative_regulation of Gene_expression of CSF2 42 0.50 38.63 8.32 99.80
144 INT181315 Regulation of DPYD 2 0.54 3.64 0 99.80
145 INT104908 Binding of B4GALNT1 7 0.05 4.62 0.82 99.80
146 INT287182 Negative_regulation of Binding of B4GALNT1 1 0.03 0.48 0.04 99.80
147 INT719 Negative_regulation of SGCG 96 0.57 47.91 30.22 99.80
148 INT13396 Gene_expression of DMD 125 0.75 57.81 5.45 99.78
149 INT142719 Binding of Col1a1 7 0.34 5.83 1.47 99.78
150 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54 99.76
151 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.76
152 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 99.74
153 INT266822 Negative_regulation of Grxcr1 10 0.10 8.12 0.17 99.74
154 INT984 Positive_regulation of Localization of GHRH 58 0.70 12.66 16.51 99.74
155 INT111081 Gene_expression of CA1 19 0.75 51.09 26.64 99.72
156 INT311552 Positive_regulation of Gene_expression of CA1 3 0.67 21.83 11.2 99.72
157 INT49238 Protein_catabolism of COL1A2 30 0.97 15.64 3.45 99.72
158 INT59137 Protein_catabolism of CTSB 5 0.96 3.92 0.62 99.72
159 INT156926 Protein_catabolism of Vsig2 5 0.57 2.01 0.64 99.72
160 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 99.70
161 INT12292 Negative_regulation of Positive_regulation of GH1 22 0.58 5.02 8.28 99.70
162 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 99.68
163 INT173809 Positive_regulation of TRMT2A 4 0.01 2.21 0.18 99.68
164 INT846 Positive_regulation of B2M 42 0.70 29.78 8.06 99.68
165 INT171017 Localization of IL11 9 0.64 4.83 0.76 99.68
166 INT2544 Localization of PTH 39 0.81 30.55 2.22 99.66
167 INT91527 Gene_expression of CTSK 38 0.78 22.21 7.42 99.66
168 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98 99.66
169 INT94690 Gene_expression of DPYD 12 0.75 4.6 1.07 99.66
170 INT2243 Localization of GAST 67 0.81 34.54 16.19 99.64
171 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 99.64
172 INT332592 Binding of MND1 1 0.08 9.21 0.16 99.64
173 INT106740 Regulation of Ugcg 14 0.22 11.5 1.88 99.64
174 INT167957 Gene_expression of Grxcr1 8 0.10 3.43 0.14 99.64
175 INT171962 Gene_expression of Tnfrsf11a 40 0.72 31.1 7.84 99.60
176 INT120650 Negative_regulation of UPF1 14 0.02 6.86 2.14 99.60
177 INT175557 Negative_regulation of Gene_expression of CASR 2 0.55 1.73 0.07 99.60
178 INT132718 Regulation of PAX5 3 0.16 1.36 0.09 99.60
179 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 99.60
180 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 99.58
181 INT46530 Gene_expression of Pthlh 15 0.78 11.23 1.7 99.58
182 INT249 Localization of GHRH 215 0.80 78.02 51.87 99.58
183 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.56
184 INT3824 Negative_regulation of PTH 40 0.59 28.58 3.39 99.56
185 INT23030 Positive_regulation of Pth 13 0.61 9.24 0.97 99.56
186 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47 99.56
187 INT125804 Localization of Pth 9 0.69 3.93 0.29 99.56
188 INT4241 Regulation of CALCA 87 0.62 28.19 55.29 99.56
189 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 99.56
190 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 99.54
191 INT64185 Gene_expression of TNFRSF11A 131 0.76 75.15 24.73 99.52
192 INT89484 Gene_expression of TNFRSF11B 119 0.76 53.57 19.67 99.52
193 INT6516 Positive_regulation of BGLAP 45 0.67 26.61 9.9 99.52
194 INT2649 Regulation of Calca 433 0.62 146.05 330.95 99.52
195 INT921 Regulation of GH1 172 0.60 52.88 51.04 99.52
196 INT184303 Positive_regulation of Bglap 16 0.66 8.66 1.25 99.52
197 INT186675 Negative_regulation of Protein_catabolism of PTH 1 0.15 1.03 0.05 99.52
198 INT340249 Positive_regulation of Positive_regulation of BGLAP 1 0.04 0.95 0.21 99.52
199 INT209893 Positive_regulation of Gene_expression of TNFRSF11B 31 0.68 11.77 4.8 99.50
200 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29 99.48
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