D:Hypergammaglobulinemia

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Disease Term
Synonyms HYPERGAMMAGLOBULINEMIAS, HYPERIMMUNOGLOBULINEMIA, Hyperimmunoglobulinemias
Documents 136
Hot Single Events 106
Hot Interactions 5

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hypergammaglobulinemia. They are ordered first by their relevance to Hypergammaglobulinemia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT180345 Binding of HLA-DMA and HLA-DRB4 1 0.00 1.51 0.12 98.68
2 INT215461 Binding of MLL and TNFSF13B 1 0.01 1.62 0.1 92.72
3 INT184379 Positive_regulation of Binding of Fcgrt and IgG 1 0.13 0.93 0.15 91.84
4 INT184380 Binding of Fcgrt and IgG 3 0.27 1.85 0.38 90.64
5 INT49283 Binding of IGLL1 and IFNK 1 0.02 0.9 0.1 87.76
6 INT329839 Negative_regulation of Tnfsf13b Negative_regulation of Gene_expression of Ighm 1 0.05 2.28 0.06 73.36
7 INT220115 Mefv Regulation of Gene_expression of Il1 1 0.01 1.85 0.13 71.36
8 INT111080 Binding of CA1 and CA2 2 0.02 1.62 0.73 71.04
9 INT254286 Binding of TNFSF13B and TNFRSF13C 1 0.07 1.26 0.08 70.24
10 INT180346 Binding of PRTN3 and SMN1 1 0.00 3.22 0 64.92
11 INT180347 Binding of PRTN3 and BTG3 1 0.00 1.9 0 64.92
12 INT354889 Binding of TNF and Gtf3a 1 0.00 2.05 0 56.36
13 INT354890 Binding of TNF and Tnfsf13b 1 0.01 2.05 0 56.04
14 INT354887 Binding of Tnfsf13b and Gtf3a 1 0.01 2.05 0 56.04
15 INT228111 Il10 Negative_regulation of Gene_expression of Ik 1 0.01 0.44 0.13 50.04
16 INT228119 Il10 Negative_regulation of H2 1 0.07 0.38 0.13 50.04
17 INT228113 H2 Negative_regulation of Gene_expression of Ik 1 0.00 0.33 0.13 46.28
18 INT185997 Binding of FANCB and fc 2 0.01 2.51 0.63 44.88
19 INT225083 Binding of ETF1 and fc 1 0.00 2.13 0.57 44.88
20 INT225082 Binding of IGHG3 and fc 6 0.01 3.6 0.55 44.88
21 INT83422 Binding of FANCB and IGHG3 3 0.12 5.09 1.22 44.64
22 INT225067 Binding of ETF1 and IGHG3 1 0.03 4.52 1.17 44.64
23 INT225065 Binding of ETF1 and FANCB 1 0.01 2.07 0.59 44.32
24 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 39.00
25 INT258399 Binding of IL6R and IL6ST 1 0.06 0.61 0.18 38.80
26 INT258398 Binding of IL6R and JAK1 1 0.01 0.75 0.23 35.12
27 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 34.68
28 INT186860 MIR181A2HG Regulation of Cd86 1 0.02 1.05 0.07 28.52
29 INT186814 MIR181A2HG Regulation of ICAM1 1 0.01 1.05 0.07 28.52
30 INT150393 Binding of CASP1 and MEFV 2 0.16 2.48 0.45 24.40
31 INT334879 CASP1 Regulation of IL1B 1 0.03 1.63 0.31 23.20
32 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
33 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29 5.00
34 INT220117 Il6 Positive_regulation of TNF 1 0.01 2.45 0.63 5.00
35 INT333476 IL12B Positive_regulation of Localization of AFP 1 0.03 0.26 0.57 5.00
36 INT333477 CXCL10 Positive_regulation of TH1L 1 0.14 0.32 0.56 5.00
37 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46 5.00
38 INT296945 ADIPOQ Negative_regulation of TNF 1 0.03 1.13 0.4 5.00
39 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34 5.00
40 INT236955 Binding of Cxcr5 and Cxcl13 1 0.28 2.26 0.34 5.00
41 INT254287 Binding of TNFSF13B and TNFRSF13B 1 0.01 1.33 0.3 5.00
42 INT254288 Binding of ZNF623 and TNFSF13B 1 0.00 1.33 0.3 5.00
43 INT287794 Binding of IGHG3 and AIP 1 0.05 2.8 0.24 5.00
44 INT184381 Binding of fc and Fcgrt 1 0.07 0.81 0.23 5.00
45 INT329841 Il4 Regulation of Hand1 1 0.04 0.87 0.18 5.00
46 INT276301 Binding of CCL21 and CXCL13 1 0.04 1.85 0.18 5.00
47 INT329843 Il4 Regulation of Hand2 1 0.04 0.87 0.18 5.00
48 INT184388 Binding of fc and DNAI1 1 0.01 1.06 0.15 5.00
49 INT198307 IL10 Positive_regulation of Gene_expression of IGHG3 2 0.01 1.21 0.15 5.00
50 INT331628 Binding of HLA-DQA2 and Pain1 1 0.01 2.13 0.14 5.00
51 INT331627 Binding of HLA-DRB3 and Pain1 1 0.00 2.15 0.14 5.00
52 INT272776 CD40 Positive_regulation of Gene_expression of IGHG3 1 0.01 0.18 0.14 5.00
53 INT354888 Amy1 Regulation of Il10 1 0.02 1.41 0.13 5.00
54 INT354885 Amy1 Regulation of Gene_expression of Il10 1 0.03 1.41 0.13 5.00
55 INT228110 Chrm2 Positive_regulation of Localization of Il10 1 0.33 0.66 0.13 5.00
56 INT331612 ETV4 Positive_regulation of Gene_expression of TGFB1 1 0.00 1.32 0.12 5.00
57 INT220114 Tnfrsf1a Positive_regulation of Esr1 1 0.14 1.14 0.1 5.00
58 INT221068 Cd79a Regulation of Gene_expression of IgG 1 0.01 0.93 0.1 5.00
59 INT221067 Cd79a Regulation of IgG 1 0.01 0.93 0.1 5.00
60 INT221066 Cd79a Regulation of Gene_expression of Ighm 1 0.01 0.93 0.1 5.00
61 INT220116 Tnfrsf1a Negative_regulation of TNF 1 0.06 0.56 0.09 5.00
62 INT276304 PRDM1 Regulation of TSC1 1 0.01 1.29 0.09 5.00
63 INT276391 Prdm1 Regulation of TSC1 1 0.00 1.29 0.09 5.00
64 INT228116 Tlr4 Positive_regulation of Localization of Il10 1 0.09 0.06 0.08 5.00
65 INT276375 Binding of Prdm1 and MIR9-1 1 0.12 1.12 0.08 5.00
66 INT276383 Binding of PRDM1 and Mirlet7a-1 1 0.39 1.12 0.08 5.00
67 INT276334 Binding of Prdm1 and Mirlet7a-1 1 0.12 1.13 0.08 5.00
68 INT276384 Binding of Mirlet7a-1 and MIR9-1 1 0.39 1.12 0.08 5.00
69 INT331626 Edn1 Positive_regulation of Itk 1 0.00 0.57 0.07 5.00
70 INT225068 Binding of FCAR and IGHG3 1 0.02 0.27 0.07 5.00
71 INT331629 Binding of TGFB1 and Positive_regulation of Gene_expression of Itk 1 0.00 0.84 0.07 5.00
72 INT225081 Binding of FCAR and fc 1 0.00 0.27 0.07 5.00
73 INT225064 Binding of IGHA1 and IGHG3 1 0.01 1.54 0.07 5.00
74 INT180344 CYP2A6 Regulation of AMELX 1 0.01 2.01 0.05 5.00
75 INT276337 Timp1 Positive_regulation of Il10 1 0.01 0.76 0.05 5.00
76 INT180373 CYP2A6 Regulation of Cyp2d4 1 0.05 2.01 0.05 5.00
77 INT180372 CYP2A6 Regulation of Cyp1a2 1 0.03 2.02 0.05 5.00
78 INT180348 CYP2A6 Regulation of AIRE 1 0.01 2.01 0.05 5.00
79 INT276386 Gtf3a Regulation of PTPN6 1 0.00 0.86 0.04 5.00
80 INT276381 Timp1 Positive_regulation of CD44 1 0.07 0.72 0.04 5.00
81 INT276392 Timp1 Regulation of PTPN6 1 0.02 0.87 0.04 5.00
82 INT276376 Gtf3a Regulation of CD44 1 0.00 0.86 0.04 5.00
83 INT276385 Timp1 Regulation of CD44 1 0.04 0.87 0.04 5.00
84 INT276377 Binding of Lgals1 and KRT20 1 0.00 1.11 0.03 5.00
85 INT276388 Il22 Positive_regulation of STAT3 1 0.03 1.3 0.03 5.00
86 INT276305 Binding of LGALS1 and KRT20 1 0.01 1.11 0.03 5.00
87 INT276389 Binding of Trp53 and KRT20 1 0.01 0.97 0.03 5.00
88 INT186502 Binding of AMELX and HLA-A 1 0.00 0.71 0 5.00
89 INT334471 Arhgdia Negative_regulation of Cdc42ep3 1 0.00 0 0 5.00
90 INT228120 PDLIM7 Positive_regulation of Localization of Il10 1 0.51 1.37 0 5.00
91 INT228117 Chrm2 Positive_regulation of Positive_regulation of Il10 1 0.22 0.61 0 5.00
92 INT276382 Binding of CIB1 and Skp2 1 0.01 0.57 0 5.00
93 INT334472 Gopc Regulation of Positive_regulation of Rhoa 1 0.02 0.3 0 5.00
94 INT225084 IGHG3 Negative_regulation of fc 1 0.01 0.24 0 5.00
95 INT180351 Binding of TNFRSF25 and ENAM 1 0.01 1.85 0 5.00
96 INT276300 TAT Regulation of Gene_expression of VEGFA 1 0.14 1.58 0 5.00
97 INT228108 Il10 Negative_regulation of H2-Eb1 1 0.04 1.38 0 5.00
98 INT288829 Binding of Rhoa and Rac1 2 0.21 1.88 0 5.00
99 INT276390 Positive_regulation of CD40 Positive_regulation of Gene_expression of Pdcd1 1 0.01 1.06 0 5.00
100 INT276378 CD40 Positive_regulation of Gene_expression of Pdcd1 1 0.01 1.06 0 5.00
101 INT331611 NKX2-1 Regulation of Transcription of SFTPB 1 0.01 0.49 0 5.00
102 INT276387 ALK Positive_regulation of Gene_expression of Il22ra1 1 0.00 1.55 0 5.00
103 INT334469 Gopc Regulation of Localization of Rhoa 1 0.02 0.3 0 5.00
104 INT228118 Binding of Fyn and Vav1 1 0.11 0.21 0 5.00
105 INT334473 PGGT1B Regulation of Localization of Rhoa 1 0.04 0.47 0 5.00
106 INT228112 Gene_expression of Chrm2 Positive_regulation of Positive_regulation of Rac1 1 0.14 0.26 0 5.00
107 INT276380 Binding of PIM1 and Trp53 1 0.01 0.66 0 5.00
108 INT180349 Binding of AMELX and BTG3 1 0.00 0.56 0 5.00
109 INT276379 Binding of SKP2 and Cdkn1b 1 0.02 0.57 0 5.00
110 INT334474 PGGT1B Regulation of Localization of Rac1 1 0.03 0.47 0 5.00
111 INT276303 Negative_regulation of AKT1 Negative_regulation of CCND1 1 0.01 0.58 0 5.00
112 INT272775 IL2 Positive_regulation of Gene_expression of IGHG3 1 0.01 0.16 0 5.00
113 INT228109 Binding of Atm and Chrm2 1 0.09 0.21 0 5.00
114 INT228115 Gene_expression of Chrm2 Positive_regulation of Phosphorylation of Vav1 1 0.16 0.26 0 5.00
115 INT326383 Binding of Rhoa and Gopc 2 0.04 0.89 0 5.00
116 INT276336 Skp2 Regulation of Cdkn1b 1 0.00 0.57 0 5.00
117 INT228114 Chrm2 Positive_regulation of Gene_expression of Il10 1 0.22 0.61 0 5.00
118 INT276374 Skp2 Regulation of Protein_catabolism of CIB1 1 0.00 0.58 0 5.00
119 INT334468 Rhoa Regulation of Localization of Rac1 1 0.25 0.18 0 5.00
120 INT276335 Binding of Cdkn1b and Skp2 1 0.00 0.57 0 5.00
121 INT276333 Binding of Il10rb and Il22ra1 1 0.00 1.25 0 5.00
122 INT276302 Binding of SKP2 and CIB1 1 0.03 0.57 0 5.00
123 INT225080 Positive_regulation of IGHG3 Negative_regulation of fc 1 0.01 0.24 0 5.00
124 INT214886 Binding of Atcay and FIP1L1 1 0.08 4.06 0 5.00
125 INT214885 Binding of PDGFRA and Atcay 1 0.08 4.05 0 5.00
126 INT276393 Skp2 Regulation of CIB1 1 0.00 0.57 0 5.00
127 INT180350 Binding of HLA-DMA and ENAM 1 0.00 1.85 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hypergammaglobulinemia. They are ordered first by their pain relevance and then by number of times they were reported in Hypergammaglobulinemia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 100.00
2 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 100.00
3 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44 100.00
4 INT49266 Positive_regulation of Arigg4 37 0.47 53.79 11.2 99.96
5 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 99.96
6 INT2725 Positive_regulation of FCER2 23 0.69 23.08 4.7 99.96
7 INT317746 Positive_regulation of Gene_expression of FCER2 2 0.01 4.09 0.3 99.96
8 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 99.90
9 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 99.88
10 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 99.82
11 INT46169 Transcription of IgG 14 0.67 7.71 1.01 99.78
12 INT254253 Transcription of Ighm 5 0.45 3.6 0.81 99.78
13 INT241132 Transcription of Cd79a 2 0.27 1.96 0 99.78
14 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 99.76
15 INT32421 Gene_expression of FCER2 19 0.73 17.23 2.53 99.76
16 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 99.70
17 INT13139 Negative_regulation of Cd4 27 0.47 17.49 6.61 99.70
18 INT27551 Gene_expression of SERPINH1 45 0.62 42.87 9.04 99.68
19 INT215469 Positive_regulation of TNFSF13B 9 0.43 7.14 0.7 99.64
20 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 99.62
21 INT19399 Gene_expression of Rf 43 0.36 33.39 13.53 99.58
22 INT13520 Binding of HLA-DRB4 30 0.42 32.65 6.74 99.34
23 INT79477 Binding of HLA-DMA 19 0.26 13.78 3.47 99.34
24 INT113219 Binding of TNFRSF25 12 0.35 9.77 0.46 99.34
25 INT8798 Positive_regulation of Csrp1 61 0.69 63.86 14.14 99.04
26 INT17417 Positive_regulation of Ighd 16 0.69 24.29 2.8 98.68
27 INT725 Negative_regulation of IgG 62 0.41 37.21 8.16 98.52
28 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 98.44
29 INT192791 Negative_regulation of MVK 3 0.16 5.64 0.25 98.28
30 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 98.00
31 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97 97.60
32 INT96164 Positive_regulation of CA1 8 0.67 10.99 6.23 97.60
33 INT250281 Positive_regulation of Positive_regulation of CD40LG 3 0.23 3.19 0.73 97.52
34 INT237075 Gene_expression of Spn 5 0.42 5.18 0.56 97.28
35 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 97.22
36 INT111081 Gene_expression of CA1 19 0.75 51.09 26.64 97.00
37 INT23533 Gene_expression of CA2 110 0.75 30.81 19.4 97.00
38 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 96.88
39 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 96.84
40 INT228088 Localization of Ceacam1 6 0.54 4.64 0.85 96.80
41 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 96.76
42 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 96.76
43 INT62031 Gene_expression of Cd19 27 0.65 10.39 0.93 96.56
44 INT201346 Negative_regulation of Gene_expression of Cd19 3 0.32 2.1 0.05 96.56
45 INT151689 Positive_regulation of Gene_expression of CADM1 6 0.08 4.31 1.02 96.20
46 INT44602 Gene_expression of TNFSF13B 37 0.75 30.98 9.96 95.92
47 INT182231 Negative_regulation of Gene_expression of CXCR5 6 0.47 6.35 2.65 95.88
48 INT17886 Negative_regulation of Il1 95 0.57 70.91 31.25 95.84
49 INT22481 Gene_expression of CADM1 28 0.65 30.26 8.5 95.84
50 INT182223 Gene_expression of CXCR5 57 0.76 51.49 28.4 95.48
51 INT3699 Gene_expression of H2-Ab1 24 0.74 12.06 11.82 95.32
52 INT137615 Regulation of Gene_expression of H2-Ab1 2 0.59 1.32 0.28 95.32
53 INT68244 Positive_regulation of Ighg1 60 0.61 48.86 5.01 94.40
54 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31 94.32
55 INT107641 Negative_regulation of Ighg1 19 0.39 11.44 1.54 94.28
56 INT28815 Gene_expression of Ighd 18 0.65 11.02 2.48 93.84
57 INT846 Positive_regulation of B2M 42 0.70 29.78 8.06 93.68
58 INT180332 Gene_expression of Sla 6 0.17 9.77 0.16 93.60
59 INT224248 Positive_regulation of Gene_expression of Sla 1 0.03 0.86 0.1 93.60
60 INT25433 Positive_regulation of Gene_expression of Rf 3 0.03 2.07 1.45 93.48
61 INT2241 Negative_regulation of CEL 56 0.58 29.32 8.83 93.12
62 INT167038 Binding of Aip 2 0.21 2.13 0.19 92.84
63 INT615 Regulation of Alb 66 0.62 33.43 15.33 92.72
64 INT76313 Gene_expression of CD38 30 0.64 20.74 5.27 92.68
65 INT354859 Localization of Cacna1s 1 0.05 3.15 0.15 92.32
66 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 91.96
67 INT68243 Regulation of Gene_expression of IgG 10 0.44 4.93 2.04 91.96
68 INT46221 Positive_regulation of Gene_expression of IgG 46 0.53 33.66 7.7 91.84
69 INT19330 Binding of HLA-A 99 0.48 76.26 22.85 91.48
70 INT21406 Negative_regulation of Gene_expression of IgG 20 0.41 9.36 3.58 91.00
71 INT9220 Gene_expression of Ighg1 125 0.77 85.74 15.92 90.92
72 INT87199 Negative_regulation of PSS 9 0.50 5.66 0.68 90.64
73 INT250545 Regulation of Hmgcr 5 0.11 4.94 0.23 88.56
74 INT23620 Negative_regulation of C4A 24 0.57 15.1 2.23 88.40
75 INT49286 Binding of IFNK 2 0.25 2.48 0.34 87.76
76 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 87.48
77 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 87.08
78 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89 87.08
79 INT254301 Regulation of TNFSF13B 1 0.28 1.09 0.07 87.00
80 INT168081 Binding of Ftcd 1 0.09 1.07 0.17 86.24
81 INT150223 Regulation of Gene_expression of TNFSF13B 2 0.21 3.44 1.8 86.04
82 INT9210 Regulation of IL6 166 0.62 125.61 49.95 86.00
83 INT1920 Positive_regulation of Positive_regulation of PLAT 3 0.40 2.29 0.22 85.44
84 INT186856 Positive_regulation of Binding of PLAT 1 0.13 0.69 0.15 85.44
85 INT9837 Negative_regulation of Rf 12 0.11 8.41 4.55 85.04
86 INT1926 Positive_regulation of PLAT 54 0.66 31.42 6.49 84.80
87 INT10101 Binding of PLAT 24 0.36 12.62 2.78 84.80
88 INT49284 Regulation of MYOM2 2 0.08 3.27 0.13 84.76
89 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 84.20
90 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6 84.08
91 INT24741 Positive_regulation of Rf 16 0.17 18.23 4.75 83.48
92 INT46142 Gene_expression of Chka 18 0.19 16.4 1.84 83.44
93 INT4137 Positive_regulation of C3 73 0.69 48.57 12.63 83.36
94 INT116362 Positive_regulation of C4A 17 0.69 11.53 1.03 83.36
95 INT236841 Negative_regulation of Gene_expression of CXCL13 3 0.27 2.17 0.83 83.36
96 INT96840 Negative_regulation of H2-K1 7 0.33 1.35 0.67 83.36
97 INT182240 Gene_expression of CXCL13 25 0.59 22.77 11.96 83.00
98 INT154613 Regulation of Aip 5 0.21 3.86 0.55 83.00
99 INT65889 Gene_expression of RETNLB 73 0.34 60.98 38.3 82.60
100 INT284359 Negative_regulation of Mvk 4 0.37 6.62 0.99 82.56
101 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 82.48
102 INT168082 Gene_expression of Ftcd 1 0.15 1.03 0.17 82.48
103 INT168083 Gene_expression of SEPSECS 1 0.11 1.03 0.17 82.48
104 INT72747 Localization of IgG 55 0.53 30.88 4.19 82.16
105 INT184370 Localization of Fcgrt 3 0.66 2.76 0.63 81.28
106 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 80.16
107 INT334449 Transcription of Mvk 1 0.44 2.18 0.33 79.92
108 INT334440 Negative_regulation of Transcription of Mvk 1 0.27 2.18 0.33 79.92
109 INT317823 Positive_regulation of Negative_regulation of Mvk 2 0.30 3.33 0.62 79.60
110 INT276329 Binding of Chka 1 0.05 5.74 0 79.12
111 INT3535 Regulation of CA2 61 0.32 16.48 10.8 78.32
112 INT2073 Regulation of CA1 5 0.26 4.9 3.86 78.32
113 INT9223 Localization of Ighg1 22 0.78 11.03 3.67 78.00
114 INT27268 Localization of Gtf3a 71 0.21 56.93 12.51 76.72
115 INT150219 Localization of TNFSF13B 2 0.47 5.91 1.15 76.72
116 INT254306 Localization of TNFRSF13B 1 0.03 1.26 0.08 76.72
117 INT254307 Localization of TNFRSF13C 1 0.14 1.05 0.07 76.72
118 INT112989 Gene_expression of AIP 3 0.56 25.4 4.23 76.56
119 INT129231 Gene_expression of Ddx41 29 0.63 9.73 1.52 75.20
120 INT36221 Positive_regulation of Nlrp3 25 0.68 19.7 4.5 75.12
121 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 75.00
122 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 75.00
123 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 75.00
124 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38 75.00
125 INT16445 Gene_expression of IL1A 60 0.78 44.46 19.19 75.00
126 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 75.00
127 INT192786 Positive_regulation of Gene_expression of Ighd 2 0.11 2.26 0.05 75.00
128 INT19475 Positive_regulation of IL1A 20 0.67 17.99 7.57 75.00
129 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 75.00
130 INT22454 Regulation of Crp 213 0.62 160.67 49.24 75.00
131 INT52625 Regulation of IL1RN 30 0.61 19.12 11.31 75.00
132 INT186629 Gene_expression of HLA-F 2 0.22 0.9 0.24 74.48
133 INT186848 Negative_regulation of Gene_expression of HLA-F 1 0.07 0.59 0.11 74.48
134 INT120062 Binding of AIP 4 0.42 28.86 3.91 73.96
135 INT329838 Negative_regulation of Tnfsf13b 4 0.19 3.81 0.2 73.36
136 INT15982 Positive_regulation of NLRP3 25 0.65 23.19 3.57 73.12
137 INT149669 Positive_regulation of MEFV 12 0.46 14.17 2.07 73.12
138 INT52899 Positive_regulation of TNFRSF1A 16 0.46 19.04 3.34 73.12
139 INT222205 Positive_regulation of PSTPIP1 8 0.69 4.69 0.62 73.12
140 INT10870 Regulation of IgG 67 0.59 43.27 12.74 72.36
141 INT150217 Binding of TNFSF13B 2 0.30 4.41 0.84 72.28
142 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 72.24
143 INT2006 Gene_expression of fc 104 0.34 64.91 19.08 72.24
144 INT184339 Gene_expression of Fcgrt 7 0.68 5.86 0.28 72.24
145 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 71.36
146 INT184354 Negative_regulation of Fcgrt 1 0.26 1.44 0.34 71.24
147 INT109910 Gene_expression of CCL16 104 0.74 76.1 43.97 71.24
148 INT92260 Binding of Nlrp3 14 0.46 8.94 2.13 71.24
149 INT203688 Positive_regulation of Hmgcr 10 0.17 6.08 0.52 71.12
150 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 70.64
151 INT85417 Positive_regulation of Gene_expression of IK 17 0.09 9.38 5.73 70.64
152 INT5864 Localization of IL36RN 19 0.44 14.5 6.87 70.00
153 INT254304 Negative_regulation of Binding of TNFSF13B 1 0.37 0.85 0.04 68.80
154 INT6852 Localization of TNF 883 0.81 705.95 270.84 68.56
155 INT274601 Regulation of PSTPIP1 3 0.45 3.76 0.28 67.96
156 INT334446 Regulation of Mvk 1 0.29 1.37 0.18 67.92
157 INT56610 Positive_regulation of Gene_expression of Chka 3 0.10 5.4 0.3 67.40
158 INT96524 Positive_regulation of Positive_regulation of Chka 2 0.41 2.36 0.12 67.40
159 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 67.24
160 INT4003 Positive_regulation of Gene_expression of IGHG3 31 0.46 20.38 3.16 67.24
161 INT226028 Gene_expression of Trove2 4 0.65 9.97 0.54 67.04
162 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 66.24
163 INT96523 Positive_regulation of Chka 5 0.69 3.78 0.19 66.04
164 INT181971 Transcription of Gpi1 3 0.37 1.29 0.67 64.76
165 INT184344 Transcription of Phgdh 1 0.67 0.75 0.17 64.76
166 INT52021 Regulation of IGHG3 34 0.39 22.43 3.3 64.40
167 INT21999 Regulation of Gene_expression of IGHG3 8 0.30 3.26 1.84 64.40
168 INT287796 Regulation of Positive_regulation of IGHG3 1 0.02 1.19 0.03 64.40
169 INT655 Positive_regulation of Localization of REN 86 0.70 32.41 13.56 64.36
170 INT49285 Regulation of IFNK 1 0.18 0.81 0.06 63.92
171 INT108273 Gene_expression of Phgdh 7 0.65 2.29 1.48 63.84
172 INT654 Localization of REN 250 0.81 75.12 47.86 63.48
173 INT1126 Negative_regulation of CD79A 46 0.59 31.07 6 63.48
174 INT38672 Binding of KRT20 69 0.39 48.01 6.31 62.64
175 INT90792 Localization of Il10 144 0.80 87.88 30.03 62.16
176 INT129164 Binding of Cd22 6 0.19 4.46 0.57 61.80
177 INT101105 Positive_regulation of FUT1 62 0.30 55.96 9.28 61.48
178 INT66923 Localization of Ik 54 0.07 19.78 20.84 60.40
179 INT8548 Gene_expression of HP 86 0.77 47.62 11.94 60.32
180 INT254303 Binding of TNFRSF13B 1 0.02 1.07 0.04 59.36
181 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 59.32
182 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 59.12
183 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 58.28
184 INT28680 Positive_regulation of Tnfsf13b 5 0.39 6.46 1.1 58.16
185 INT16449 Binding of IGHG3 67 0.48 39.55 10.59 57.60
186 INT296947 Binding of ISM1 1 0.15 4.54 0.46 57.20
187 INT130392 Positive_regulation of Gene_expression of HP 7 0.69 7.34 1.9 55.44
188 INT184360 Negative_regulation of Negative_regulation of Fcgrt 1 0.26 0.72 0.18 55.12
189 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 54.80
190 INT77523 Positive_regulation of ADC 14 0.63 13.81 1.81 53.92
191 INT254299 Protein_catabolism of TNFSF13B 1 0.41 1.02 0.05 53.92
192 INT181806 Positive_regulation of Gene_expression of Atxn1 6 0.41 2.85 0.21 53.68
193 INT229573 Positive_regulation of Positive_regulation of Kit 3 0.39 1.46 0.09 53.68
194 INT181809 Gene_expression of Atxn1 81 0.77 28.66 1.42 53.20
195 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 53.12
196 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 53.12
197 INT210218 Localization of Tnfsf13b 2 0.40 4.76 0.22 52.48
198 INT354864 Positive_regulation of Localization of Tnfsf13b 1 0.16 4.03 0 52.48
199 INT167056 Gene_expression of CALR 29 0.75 20.05 1.25 51.84
200 INT124185 Negative_regulation of Kit 57 0.59 35.43 3.61 51.68
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