D:Hyperglycemia

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Disease Term
Synonyms Hyperglycemias
Documents 1394
Hot Single Events 200
Hot Interactions 136

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hyperglycemia. They are ordered first by their relevance to Hyperglycemia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT99728 Binding of F13A1 and PLG 4 0.02 2.51 0.63 100.00
2 INT180958 Binding of F13A1 and PLAT 2 0.03 2.16 0.47 100.00
3 INT321408 INS Positive_regulation of EGR1 1 0.03 2.36 0.13 100.00
4 INT321414 INS Positive_regulation of Transcription of EGR1 1 0.03 2.36 0.13 100.00
5 INT240769 Positive_regulation of Binding of F13A1 and PLG 1 0.02 0.9 0.04 100.00
6 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 100.00
7 INT323502 Ghrl Positive_regulation of Localization of Ins1 1 0.15 1.58 0.33 100.00
8 INT339711 TRO Regulation of PPARA 1 0.09 0.97 0.06 100.00
9 INT141623 OLR1 Positive_regulation of Gene_expression of TF 1 0.01 1.39 0.21 99.92
10 INT230818 Ins1 Positive_regulation of Gene_expression of Agt 1 0.07 1.11 0.04 99.90
11 INT230820 Ins1 Positive_regulation of ras 1 0.12 1.1 0.04 99.90
12 INT230817 Ins1 Positive_regulation of Regulation of Agt 1 0.07 1.11 0.04 99.90
13 INT246684 exf Regulation of Gene_expression of Ros1 1 0.00 0.42 0.22 99.84
14 INT321401 Gene_expression of ROS1 Negative_regulation of Positive_regulation of AKR1B1 1 0.01 0.8 0.05 99.78
15 INT141625 Crp Positive_regulation of Gene_expression of TF 1 0.11 1.39 0.21 99.64
16 INT246688 exf Negative_regulation of Gene_expression of Ros1 1 0.01 0.43 0.25 99.54
17 INT189671 DAG1 Positive_regulation of PRKCA 3 0.12 0.71 0.82 99.50
18 INT258148 Gene_expression of IGFBP3 Negative_regulation of Hcrt 1 0.28 0.86 0.04 99.32
19 INT239236 Prkca Regulation of CYBB 1 0.00 0.98 0.2 99.20
20 INT239235 Prkca Positive_regulation of Prkca Regulation of Nos3 1 0.01 0.97 0.2 99.20
21 INT239227 Prkca Regulation of Nos3 1 0.02 0.97 0.2 99.20
22 INT321410 EGR1 Negative_regulation of Gene_expression of TNFSF10 1 0.10 2.07 0.12 98.76
23 INT253086 INS Negative_regulation of LPL 1 0.08 0.56 0 98.60
24 INT230760 VEGFA Positive_regulation of Flt1 1 0.03 0.96 0.12 98.52
25 INT230761 VEGFA Positive_regulation of Kdr 2 0.02 2.16 0.12 98.52
26 INT100783 Binding of CYP2B6 and CYP3A4 2 0.17 2 0.77 98.32
27 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 0.64 2.12 14.2 98.30
28 INT242960 Binding of Ins1 and Ffar1 1 0.19 1.33 0.04 97.40
29 INT172816 Crp Positive_regulation of Transcription of Nos3 1 0.06 0.91 0.1 97.06
30 INT172817 Crp Positive_regulation of Regulation of Nos3 1 0.09 0.84 0.1 97.06
31 INT172819 Crp Positive_regulation of Gene_expression of Nos3 1 0.06 0.91 0.1 97.06
32 INT172821 Crp Positive_regulation of Negative_regulation of Nos3 1 0.06 0.84 0.1 97.06
33 INT309003 Ins1 Positive_regulation of TNF 1 0.05 1.74 0.35 97.00
34 INT230854 INS Regulation of Positive_regulation of SNAP47 1 0.09 1.03 0.03 96.60
35 INT230851 INS Regulation of VCAM1 1 0.07 1.02 0.03 96.60
36 INT314624 Ex Regulation of GCG 1 0.01 0.67 0 96.40
37 INT314621 Ex Regulation of INS 1 0.06 0.67 0 96.04
38 INT246809 Negative_regulation of Tsc2 Positive_regulation of Positive_regulation of Ogg1 1 0.20 0.45 0 95.60
39 INT240942 Ins1 Regulation of Transcription of Pck1 1 0.08 0.73 0 95.60
40 INT321399 Positive_regulation of SETD7 Positive_regulation of SETDB1 1 0.00 1.25 0.06 95.16
41 INT179493 Adipoq Positive_regulation of Ins1 1 0.20 0.99 0.12 95.16
42 INT321402 Binding of NPHS1 and PIK3CD 1 0.02 0.73 0.03 95.08
43 INT276209 Negative_regulation of Binding of Nos2 and Nfkb1 1 0.14 0.31 0.34 94.98
44 INT332629 Binding of Glp1r and Positive_regulation of Localization of Gcg 1 0.03 0.47 0 94.92
45 INT332636 Binding of Glp1r and Positive_regulation of Localization of Ins1 1 0.03 0.47 0 94.92
46 INT246686 Ide Regulation of Ros1 1 0.03 0.41 0.22 94.88
47 INT276214 Binding of Nos2 and Nfkb1 1 0.12 0.31 0.34 94.80
48 INT321398 SETD7 Positive_regulation of SETDB1 1 0.00 0.62 0.03 94.76
49 INT323486 Ghrl Regulation of Localization of Ins1 1 0.21 2.07 0.07 94.64
50 INT337848 Ros1 Positive_regulation of Gene_expression of Mapk14 1 0.14 0.27 0 94.24
51 INT230857 Negative_regulation of Binding of HSP90AA1 and NOS1 1 0.05 1.18 0.09 94.16
52 INT96563 Binding of ADRA1D and UCN2 1 0.19 1.34 0.1 93.76
53 INT246784 Negative_regulation of Tsc2 Positive_regulation of Negative_regulation of Ogg1 1 0.20 0.43 0 93.60
54 INT340299 Ea1 Regulation of Ppargc1a 1 0.03 0.41 0.16 93.60
55 INT230856 Binding of HSP90AA1 and NOS1 1 0.04 1.17 0.09 93.52
56 INT246794 Ros1 Positive_regulation of Phosphorylation of Tsc2 1 0.03 0.66 0 93.52
57 INT246782 Ros1 Positive_regulation of Positive_regulation of Akt1 1 0.06 0.66 0 93.52
58 INT246692 Zglp1 Regulation of Gene_expression of Ros1 1 0.04 0.38 0.24 92.96
59 INT246797 Tgfb1i1 Positive_regulation of Phosphorylation of Tsc2 1 0.01 0.66 0 92.64
60 INT246785 Tgfb1i1 Positive_regulation of Positive_regulation of Akt1 1 0.01 0.66 0 92.64
61 INT89384 Negative_regulation of INS Positive_regulation of AKT1 2 0.36 1.37 0.04 92.36
62 INT257878 Ins1 Positive_regulation of Gene_expression of Ntrk2 1 0.00 0.65 0.04 91.76
63 INT257877 Ins1 Positive_regulation of Phosphorylation of Ntrk2 1 0.00 0.66 0.04 91.76
64 INT328373 Negative_regulation of Ghrl Positive_regulation of Localization of GH1 1 0.05 0.31 0.08 91.76
65 INT255741 Ptch1 Positive_regulation of Phosphorylation of Ins1 1 0.09 2.21 0 91.68
66 INT89381 INS Positive_regulation of AKT1 6 0.43 3.06 0.33 91.56
67 INT332627 Positive_regulation of Ins1 Positive_regulation of Phosphorylation of Hk2 1 0.01 0.83 0 91.20
68 INT242203 GLP1R Regulation of GCG 1 0.04 0.64 0.1 91.20
69 INT348222 Binding of Ins1 and Glp1r 1 0.05 0.82 0.03 91.12
70 INT274385 Binding of ABAT and CDIPT 1 0.00 1.21 0 90.92
71 INT228455 Ins1 Positive_regulation of Prkca 1 0.02 0.98 0.12 90.84
72 INT228458 Ins1 Positive_regulation of Trpv1 1 0.06 0.98 0.12 90.84
73 INT40728 SST Regulation of IRG1 1 0.11 0.36 0.38 90.48
74 INT290861 MNT Positive_regulation of INS 1 0.03 1.78 0 90.44
75 INT258492 Binding of Ins1 and Cdipt 1 0.00 0.92 0 90.40
76 INT228453 Igf1 Positive_regulation of Prkca 2 0.12 1.17 0.12 90.36
77 INT228456 Igf1 Positive_regulation of Trpv1 1 0.24 0.97 0.12 90.36
78 INT258141 Binding of Hcrt and Gopc 1 0.06 0.93 0.06 90.08
79 INT258140 Negative_regulation of Binding of Hcrt and Gopc 1 0.07 0.94 0.06 90.08
80 INT255735 Ptch1 Positive_regulation of Phosphorylation of Akt1 1 0.27 2.83 0 89.84
81 INT314773 Glp1r Positive_regulation of Gene_expression of Pdx1 1 0.01 0.57 0 89.48
82 INT166625 Acer3 Positive_regulation of Trpa1 1 0.01 1.91 1 88.96
83 INT240808 Arc Regulation of Ins1 1 0.09 1.41 0.54 88.88
84 INT240807 Arc Regulation of Gene_expression of Lepr 1 0.05 0.72 0.28 88.88
85 INT311223 GLP1R Regulation of Localization of GCG 1 0.16 0.74 0 88.64
86 INT1312 Pomc Positive_regulation of Gnrhr 2 0.11 0.22 0.7 88.16
87 INT332641 Binding of PPARG and Ins1 1 0.12 1.05 0.05 88.12
88 INT257869 Rps6kb1 Regulation of Eif4ebp1 1 0.02 0.64 0.04 88.00
89 INT257872 Eif4ebp1 Regulation of Rps6kb1 1 0.02 0.64 0.04 88.00
90 INT314771 Glp1r Positive_regulation of Gene_expression of Ins1 2 0.04 1.23 0.03 87.88
91 INT207251 TXNIP Positive_regulation of ZNF236 1 0.03 0.84 0 87.80
92 INT90045 Oprd1 Positive_regulation of P9Ehs1 1 0.19 0.92 0.64 87.60
93 INT350020 ARID1B Regulation of Positive_regulation of Tnf 1 0.04 1.78 0.16 87.48
94 INT350013 ARID1B Regulation of Positive_regulation of NFKB1 1 0.00 1.77 0.16 87.48
95 INT324927 Syt17 Positive_regulation of Bdkrb1 1 0.04 4.29 2.96 86.96
96 INT258147 IGFBP3 Negative_regulation of Hcrt 1 0.28 1.87 0.11 86.40
97 INT246693 Zglp1 Positive_regulation of Localization of Ide 1 0.08 0.34 0.27 86.40
98 INT250025 Map3k1 Positive_regulation of Regulation of Bcl2 1 0.01 1.1 0.04 86.40
99 INT351001 Binding of Adh7 and Ins1 1 0.00 1.62 0.05 86.16
100 INT205555 Sst Negative_regulation of Ins1 1 0.05 0.77 0.14 85.84
101 INT264864 Cd38 Positive_regulation of Localization of INS 1 0.06 0.51 0 85.64
102 INT184543 Agt Positive_regulation of Ccl2 1 0.16 3.18 0.43 85.52
103 INT90046 Oprm1 Positive_regulation of P9Ehs1 2 0.16 0.92 1.63 85.52
104 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31 85.28
105 INT253122 Ins1 Positive_regulation of Akt1 2 0.15 1.81 0.14 85.28
106 INT255754 Negative_regulation of Ins1 Positive_regulation of Akt1 1 0.14 1.73 0.1 85.28
107 INT18324 Sst Negative_regulation of Localization of Ins1 2 0.46 1.09 1.24 85.20
108 INT255732 Ptch1 Positive_regulation of hs 1 0.06 1.26 0 85.08
109 INT355432 Gene_expression of Pdia3 Negative_regulation of Ddit3 1 0.04 1.29 0.06 84.08
110 INT355447 Gene_expression of Pdia3 Negative_regulation of Transcription of TNF 1 0.00 1.8 0.06 84.08
111 INT355444 Gene_expression of Pdia3 Negative_regulation of TNF 1 0.00 1.29 0.06 84.08
112 INT355433 Gene_expression of Pdia3 Negative_regulation of Transcription of Ddit3 1 0.03 1.79 0.06 84.08
113 INT355438 Gene_expression of Pdia3 Negative_regulation of Gene_expression of Ddit3 1 0.05 4.79 0.06 84.08
114 INT266811 Binding of HRH1 and HTR2C 1 0.23 2.06 1.4 83.92
115 INT230762 Binding of DAG1 and Tbx15 1 0.00 0.21 0 83.68
116 INT49242 Binding of Mc1r and Pomc 10 0.38 3.79 2.15 83.64
117 INT246691 Ide Positive_regulation of Gene_expression of Nos3 1 0.03 0.26 0.05 83.36
118 INT29257 Pomc Positive_regulation of Gcg 1 0.17 0.23 0.21 83.12
119 INT301653 Mlxipl Positive_regulation of Gene_expression of Scd1 1 0.08 0.5 0.05 83.04
120 INT246689 Zglp1 Positive_regulation of Ide 1 0.06 0.28 0.27 82.96
121 INT324925 Ros1 Positive_regulation of Bdkrb1 1 0.08 0.67 0.6 82.88
122 INT211492 Positive_regulation of GRIN1 Positive_regulation of Prkca 1 0.01 0.87 0.36 82.84
123 INT256576 Lep Regulation of Localization of Ins1 1 0.57 2.08 0.2 82.84
124 INT229286 BAS Negative_regulation of FXR1 1 0.02 0.55 0.09 82.72
125 INT229274 BAS Positive_regulation of BAS Negative_regulation of FXR1 1 0.00 0.55 0.09 82.72
126 INT332635 Glp1r Regulation of Localization of Gcg 1 0.03 0.94 0.04 82.32
127 INT249850 Binding of Ptprc and Cd34 1 0.13 0.48 0 81.92
128 INT246683 exf Regulation of Gopc 1 0.01 0.2 0.14 81.52
129 INT207253 INS Negative_regulation of TXNIP 1 0.45 1.2 0.15 81.36
130 INT242204 DPP4 Positive_regulation of Gene_expression of GLP1R 1 0.03 0.66 0.1 81.36
131 INT337729 PDX1 Regulation of Gene_expression of INS 1 0.29 0.28 0 81.24
132 INT337738 PDX1 Regulation of Positive_regulation of INS 1 0.21 0.28 0 81.24
133 INT337730 PDX1 Regulation of INS 1 0.21 0.28 0 81.24
134 INT301665 CYP2C9 Regulation of Binding of Ppara 1 0.26 1.79 0.34 81.12
135 INT165724 Bdkrb1 Positive_regulation of Adora1 1 0.24 1.65 0.43 80.80
136 INT324926 Ptpro Positive_regulation of Bdkrb2 1 0.01 2.25 1.5 80.56
137 INT223582 Negative_regulation of MTOR Positive_regulation of Phosphorylation of ESR1 1 0.31 0.67 0 79.60
138 INT176131 Binding of AKT1 and PIK3CG 2 0.15 1.08 0 79.60
139 INT262753 Binding of MTOR and PIK3CG 1 0.20 0.82 0 79.60
140 INT221085 GHRH Positive_regulation of Gene_expression of IGF1 2 0.56 1.47 0.41 79.52
141 INT178269 Slc11a2 Regulation of a 1 0.06 0.97 0.16 79.36
142 INT178266 Raly Regulation of a 1 0.14 0.97 0.16 79.36
143 INT229290 BAS Negative_regulation of LDLR 1 0.03 0.83 0.13 78.80
144 INT18325 Grem2 Positive_regulation of Ins1 1 0.02 0.9 0.88 78.76
145 INT301496 PPA1 Negative_regulation of CYP4F3 1 0.01 0.69 0.05 78.48
146 INT301497 UBXN11 Negative_regulation of CYP4F3 1 0.37 0.69 0.05 78.48
147 INT321404 Positive_regulation of MAP3K5 Positive_regulation of Gene_expression of SERPINE1 1 0.02 2.2 0.12 78.40
148 INT321842 Binding of Ros1 and SCFV 1 0.01 1.34 0.54 77.84
149 INT253138 Il6 Regulation of Ins1 1 0.13 0.76 0.07 77.52
150 INT250023 Positive_regulation of Ros1 Positive_regulation of Nfkb1 1 0.04 1.26 0.08 77.36
151 INT262307 CAPNS1 Regulation of TAF9 1 0.04 1.23 0.33 77.28
152 INT342936 Renbp Positive_regulation of Ros1 1 0.02 1.56 0.03 76.96
153 INT294708 CRP Positive_regulation of Gene_expression of VCAM1 2 0.31 1.92 0.56 76.44
154 INT250024 Positive_regulation of Ros1 Positive_regulation of Gtf3a 1 0.00 1.26 0.08 76.16
155 INT337885 Ins1 Positive_regulation of Gene_expression of Nr2f2 1 0.18 0.27 0 75.84
156 INT337886 Per1 Positive_regulation of Gene_expression of Nr2f2 1 0.09 0.16 0 75.84
157 INT301633 Binding of Ros1 and Cyb5 1 0.00 0.41 0 75.76
158 INT301634 Positive_regulation of Binding of Ros1 and Cyb5 1 0.00 0.41 0 75.76
159 INT355431 Binding of Pdia3 and Positive_regulation of Gene_expression of Ddit3 1 0.04 1.14 0.06 75.72
160 INT355440 Binding of Pdia3 and Positive_regulation of Transcription of VEGFA 1 0.01 1.15 0.06 75.72
161 INT355449 Binding of Pdia3 and Positive_regulation of Transcription of TNF 1 0.00 1.15 0.06 75.72
162 INT355443 Binding of Pdia3 and Positive_regulation of Gene_expression of TNF 1 0.00 1.15 0.06 75.72
163 INT355434 Binding of Pdia3 and Positive_regulation of Transcription of Ddit3 1 0.04 1.14 0.06 75.72
164 INT355446 Binding of Pdia3 and Positive_regulation of Gene_expression of VEGFA 1 0.01 1.15 0.06 75.72
165 INT240768 Binding of F2 and F13A1 1 0.07 2.25 0.15 75.56
166 INT240770 Binding of CD40LG and F13A1 1 0.02 1.4 0.09 75.56
167 INT337891 Per1 Positive_regulation of Nr2f2 1 0.08 0.16 0 75.28
168 INT337893 Ins1 Positive_regulation of Nr2f2 1 0.12 0.16 0 75.28
169 INT129364 Ea1 Positive_regulation of Localization of Ins1 1 0.02 0.49 0.2 75.00
170 INT240805 Positive_regulation of Binding of Glp1r and Arc 1 0.24 0.53 0.11 74.56
171 INT173130 Binding of INS and PPARA 2 0.04 1.8 0.08 74.12
172 INT312708 DPP8 Positive_regulation of DPP4 1 0.24 0.54 0.19 74.04
173 INT312706 DPP9 Positive_regulation of DPP4 1 0.26 0.54 0.19 74.04
174 INT228457 Negative_regulation of Ins1 Positive_regulation of Gene_expression of Trpv1 1 0.05 1.01 0.21 74.00
175 INT160985 Urb1 Negative_regulation of Negative_regulation of Faah 1 0.41 1.36 0.74 73.92
176 INT179492 Binding of Ins1 and Adipoq 1 0.16 1.16 0.23 73.72
177 INT301620 Positive_regulation of Binding of Ros1 and Scd1 1 0.03 0.41 0 73.60
178 INT301652 Binding of Ros1 and Scd1 1 0.02 0.41 0 73.60
179 INT142437 Urb1 Negative_regulation of Faah 3 0.41 2.12 1.66 73.56
180 INT143747 Binding of IL6 and LEP 2 0.04 4.05 0.38 73.32
181 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42 73.32
182 INT328384 Ghrl Positive_regulation of ALPL 1 0.01 0.93 0.13 73.32
183 INT240806 Binding of Glp1r and Arc 1 0.19 0.53 0.11 72.96
184 INT56111 Ins1 Regulation of Localization of Gip 1 0.13 0.23 0.09 72.92
185 INT229333 Binding of Nr1h2 and Positive_regulation of Gene_expression of SLC2A4 1 0.02 0.62 0.07 72.80
186 INT351332 Positive_regulation of Il4 Positive_regulation of Gene_expression of Il10 1 0.09 1.78 0.53 72.68
187 INT319735 Positive_regulation of Binding of IL6 and IL8 1 0.01 1.35 0.11 72.36
188 INT253145 Il6 Positive_regulation of Prkag1 1 0.11 0.73 0.44 72.28
189 INT253131 Il6 Regulation of Phosphorylation of Akt1 1 0.14 0.25 0.09 72.28
190 INT258144 IGFBP3 Regulation of Gene_expression of Hcrt 1 0.30 2.23 0.03 72.24
191 INT301639 Positive_regulation of Mlxipl Positive_regulation of Gene_expression of Pklr 1 0.03 0.52 0 72.08
192 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11 71.96
193 INT229330 Binding of Nr1h2 and Positive_regulation of Gene_expression of GCK 1 0.01 0.62 0.07 71.92
194 INT253129 Ins1 Regulation of Phosphorylation of Akt1 3 0.11 1.66 0.17 71.16
195 INT128489 IGF1 Negative_regulation of Positive_regulation of INS 1 0.26 0.38 0 70.60
196 INT242961 Ffar1 Regulation of Localization of Ins1 1 0.23 2.08 0.08 70.56
197 INT181570 Binding of Edn1 and Mapk1 1 0.13 2.72 0.1 70.24
198 INT181571 Binding of Mapk8 and Mapk1 1 0.04 1.24 0.05 70.24
199 INT166624 Acer3 Positive_regulation of Acer3 Positive_regulation of Trpa1 1 0.00 0.78 0.37 69.92
200 INT181569 Binding of Edn1 and Mapk8 1 0.09 2.7 0.1 69.72

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hyperglycemia. They are ordered first by their pain relevance and then by number of times they were reported in Hyperglycemia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT812 Localization of INS 1026 0.81 515.6 145.31 100.00
2 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 100.00
3 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 100.00
4 INT14572 Binding of INS 205 0.48 175.43 13.38 100.00
5 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91 100.00
6 INT105571 Gene_expression of SRGN 33 0.58 14.68 1.19 100.00
7 INT3866 Positive_regulation of Positive_regulation of INS 30 0.59 21.58 1.86 100.00
8 INT4360 Gene_expression of Hypism 29 0.22 38.1 4.07 100.00
9 INT231494 Regulation of Phosphorylation of Mapk14 2 0.24 2.59 0.93 100.00
10 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12 100.00
11 INT312831 Negative_regulation of Lck 3 0.13 2.46 0.36 100.00
12 INT280055 Positive_regulation of Gene_expression of SRGN 5 0.42 2.49 0.08 100.00
13 INT8744 Regulation of Localization of Gcg 14 0.60 2.06 4.3 100.00
14 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 100.00
15 INT58470 Negative_regulation of Binding of INS 14 0.43 7.2 1.01 100.00
16 INT321417 Positive_regulation of Negative_regulation of IRS1 1 0.12 3.82 0.51 100.00
17 INT250 Regulation of GHRH 65 0.61 17.46 23.19 100.00
18 INT9660 Regulation of TNF 363 0.62 312.94 139.99 100.00
19 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 100.00
20 INT39712 Binding of pad 82 0.48 110.92 10.33 100.00
21 INT182787 Binding of ETV3 14 0.37 25.44 0.37 100.00
22 INT259032 Binding of PEX1 2 0.01 4.67 0.15 100.00
23 INT145097 Negative_regulation of Pain1 16 0.22 19.11 16.82 100.00
24 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 100.00
25 INT246741 Regulation of Gene_expression of Ogg1 1 0.55 1.92 0.09 100.00
26 INT40730 Regulation of IRG1 1 0.08 0.46 0.48 100.00
27 INT174753 Gene_expression of Apoa2 15 0.75 13.82 0.41 100.00
28 INT18322 Negative_regulation of Ins1 132 0.58 88.49 22.59 99.98
29 INT72060 Positive_regulation of Gene_expression of Ros1 127 0.41 76.76 20.91 99.98
30 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27 99.98
31 INT246759 Positive_regulation of Phosphorylation of Tsc2 1 0.29 9.31 0 99.98
32 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 99.98
33 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 99.98
34 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 99.98
35 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09 99.98
36 INT7944 Positive_regulation of Fos 193 0.70 60.69 98.31 99.98
37 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 99.98
38 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 99.98
39 INT246765 Positive_regulation of Phosphorylation of Ogg1 1 0.45 1.72 0 99.98
40 INT123466 Binding of T2dm2 21 0.37 34.87 2.91 99.98
41 INT246760 Positive_regulation of Negative_regulation of Ogg1 1 0.62 1.44 0 99.98
42 INT173328 Positive_regulation of DAG1 6 0.31 1.74 1.36 99.98
43 INT49103 Positive_regulation of Vcam1 71 0.69 59.52 19.85 99.98
44 INT15166 Positive_regulation of Mme 40 0.70 13.01 16.24 99.98
45 INT249049 Positive_regulation of ARID1B 14 0.56 24.77 0.71 99.98
46 INT120401 Positive_regulation of PIK3CD 33 0.45 14.89 7.37 99.98
47 INT243007 Positive_regulation of Transcription of Angpt2 1 0.65 0.55 0 99.98
48 INT69878 Positive_regulation of Gene_expression of Gtf3a 48 0.29 36.78 13.57 99.98
49 INT8388 Positive_regulation of Vip 142 0.70 39.72 67.61 99.98
50 INT172801 Positive_regulation of Tnfsf4 4 0.08 7.95 0.44 99.98
51 INT284325 Positive_regulation of Gene_expression of DAG1 3 0.13 1.08 0.36 99.98
52 INT72166 Positive_regulation of Gene_expression of RETNLB 14 0.24 10.23 7.27 99.98
53 INT16428 Positive_regulation of Gtf3a 135 0.20 106.44 26.67 99.98
54 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.96
55 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 99.96
56 INT117502 Positive_regulation of Adipoq 70 0.63 40.43 12.03 99.96
57 INT242910 Positive_regulation of Positive_regulation of Bcl2a1c 2 0.05 2.24 0.06 99.96
58 INT51072 Positive_regulation of Positive_regulation of Htr3a 10 0.49 1.84 4.53 99.96
59 INT660 Negative_regulation of REN 194 0.59 82.06 29.46 99.96
60 INT240041 Negative_regulation of Protein_catabolism of Apob 1 0.01 1.8 0.13 99.94
61 INT3214 Localization of Ins1 527 0.80 196.9 79.26 99.92
62 INT1200 Negative_regulation of Ins1 274 0.58 155.17 56.14 99.92
63 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 99.92
64 INT18323 Negative_regulation of Localization of Ins1 122 0.58 45.74 23.04 99.92
65 INT158863 Negative_regulation of Ros1 84 0.35 40.3 10.14 99.92
66 INT224366 Gene_expression of Ager 111 0.77 125.37 8.49 99.92
67 INT3216 Positive_regulation of Localization of Ins1 170 0.69 56.78 35.63 99.92
68 INT246750 Gene_expression of Ogg1 1 0.69 10.04 0.12 99.92
69 INT112645 Negative_regulation of OVGP1 7 0.33 3.17 1.34 99.92
70 INT155234 Gene_expression of TXNIP 48 0.77 24.4 2.05 99.92
71 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 99.92
72 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 99.92
73 INT312828 Negative_regulation of Gene_expression of Ins2 1 0.37 0.8 0.12 99.92
74 INT207291 Negative_regulation of Gene_expression of TXNIP 1 0.58 3.47 0.11 99.92
75 INT155235 Negative_regulation of TXNIP 2 0.58 2.44 0.13 99.92
76 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 99.92
77 INT49483 Regulation of Positive_regulation of Oprm1 8 0.61 2.34 9.4 99.92
78 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 99.92
79 INT2093 Gene_expression of GAST 50 0.78 32.32 7.98 99.92
80 INT28059 Positive_regulation of Apol7b 7 0.03 8.19 0.44 99.92
81 INT253941 Positive_regulation of Localization of Adipoq 5 0.24 2.59 0.21 99.92
82 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 99.90
83 INT2275 Negative_regulation of Localization of Ins1 183 0.59 51.02 44.94 99.90
84 INT208291 Negative_regulation of Pten 2 0.44 5.42 3.36 99.90
85 INT48129 Negative_regulation of Slc2a4 7 0.59 3.19 1.21 99.90
86 INT255569 Negative_regulation of Gk 7 0.14 4.56 0.07 99.90
87 INT251 Regulation of INS 398 0.62 232.47 55.04 99.88
88 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49 99.88
89 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53 99.88
90 INT28739 Binding of Ins1 35 0.37 22.43 2.14 99.88
91 INT321427 Negative_regulation of Phosphorylation of NPHS1 1 0.07 0.79 0.03 99.88
92 INT321418 Negative_regulation of NPHS1 1 0.07 0.79 0.03 99.88
93 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 99.88
94 INT181818 Gene_expression of Ppargc1a 50 0.78 24.33 2.71 99.88
95 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 99.86
96 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32 99.84
97 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36 99.84
98 INT1114 Localization of Ins1 748 0.80 192.95 165.48 99.84
99 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32 99.84
100 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 99.84
101 INT314194 Phosphorylation of DRGX 1 0.01 5.19 3.26 99.84
102 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 99.84
103 INT243003 Positive_regulation of Angpt2 7 0.65 6.31 0.26 99.84
104 INT184270 Negative_regulation of AGER 8 0.32 10.48 3.45 99.84
105 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 99.84
106 INT32795 Positive_regulation of Hypism 17 0.15 20.16 1.73 99.84
107 INT1352 Localization of Acot1 728 0.80 73.01 296.01 99.84
108 INT78284 Positive_regulation of PTPRC 40 0.49 27.17 3.45 99.84
109 INT230758 Positive_regulation of Gene_expression of PTPRC 11 0.49 6.04 2.45 99.84
110 INT312827 Gene_expression of Bcap31 1 0.25 0.27 0.08 99.84
111 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79 99.82
112 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 99.82
113 INT875 Regulation of Localization of Gh1 166 0.62 12.87 84.97 99.82
114 INT243004 Transcription of Angpt2 1 0.67 0.55 0 99.82
115 INT3656 Positive_regulation of Gene_expression of Ins1 74 0.54 44.94 17.36 99.80
116 INT8748 Positive_regulation of Localization of Gcg 24 0.67 9.74 3.46 99.80
117 INT8740 Localization of Gcg 65 0.78 19 9.81 99.80
118 INT25543 Regulation of Hypism 3 0.02 2.49 0.82 99.80
119 INT1782 Regulation of Gh1 125 0.62 22 55.74 99.80
120 INT69436 Negative_regulation of Gene_expression of ROS1 81 0.38 46.58 12.22 99.78
121 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 99.78
122 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34 99.76
123 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 99.76
124 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98 99.76
125 INT68373 Negative_regulation of FLNA 59 0.57 60.46 9.55 99.76
126 INT48726 Gene_expression of IGFBP1 27 0.67 9.45 3.36 99.76
127 INT29856 Negative_regulation of Positive_regulation of Ptpn6 3 0.38 1.24 1.47 99.76
128 INT240040 Protein_catabolism of Apob 1 0.01 1.79 0.13 99.76
129 INT210539 Binding of Ide 11 0.29 6.09 0.52 99.74
130 INT124297 Gene_expression of Sod2 112 0.77 65.65 7.64 99.72
131 INT141658 Positive_regulation of Gene_expression of Sod2 51 0.69 35.6 3.71 99.72
132 INT6110 Negative_regulation of Gene_expression of Ins1 83 0.56 60.59 16.07 99.72
133 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 99.72
134 INT56494 Localization of Ide 73 0.68 22.9 11.26 99.72
135 INT183461 Positive_regulation of Positive_regulation of Ros1 6 0.13 5 0.16 99.72
136 INT144097 Negative_regulation of Hypism 4 0.18 2.88 0.3 99.72
137 INT312826 Negative_regulation of Nppc 1 0.03 1.36 0.45 99.72
138 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 99.70
139 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 99.70
140 INT56292 Negative_regulation of Gene_expression of Ros1 70 0.38 36.14 9.17 99.70
141 INT91863 Negative_regulation of Gene_expression of NOS3 13 0.51 9.43 1.34 99.70
142 INT189771 Gene_expression of DAG1 5 0.27 4.14 1.12 99.70
143 INT65889 Gene_expression of RETNLB 73 0.34 60.98 38.3 99.70
144 INT299974 Negative_regulation of Gene_expression of FTSJ3 1 0.05 0.64 0.05 99.70
145 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.68
146 INT876 Localization of Gh1 843 0.80 67.75 340.82 99.68
147 INT880 Positive_regulation of Localization of Gh1 304 0.70 14.79 150.23 99.68
148 INT115249 Binding of Slc2a4 7 0.36 2.63 0.8 99.68
149 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4 99.68
150 INT314 Positive_regulation of Ren 212 0.70 66.68 55.56 99.68
151 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 99.68
152 INT21687 Positive_regulation of ras 143 0.58 97.34 27.31 99.68
153 INT325194 Binding of Ifi30 1 0.04 0.55 0 99.68
154 INT240787 Positive_regulation of Bcl2a1c 12 0.22 9.79 0.06 99.66
155 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84 99.66
156 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14 99.66
157 INT84495 Positive_regulation of Positive_regulation of Ephb1 85 0.70 46.12 54.11 99.66
158 INT246770 Positive_regulation of Negative_regulation of Tsc2 1 0.20 1.91 0.05 99.64
159 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05 99.62
160 INT227273 Localization of Adipoq 22 0.72 18.04 1.72 99.62
161 INT246762 Phosphorylation of Tsc2 60 0.67 15.71 0.25 99.60
162 INT246749 Negative_regulation of Phosphorylation of Tsc2 11 0.35 3.4 0.12 99.60
163 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93 99.60
164 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 99.60
165 INT34669 Localization of Hypism 8 0.25 10.79 1.2 99.60
166 INT48959 Positive_regulation of Positive_regulation of Prkcg 52 0.70 16.47 36.49 99.60
167 INT57360 Gene_expression of STAR 31 0.66 12.72 2.24 99.60
168 INT23191 Gene_expression of HDLCQ1 13 0.60 14.39 1.58 99.60
169 INT72703 Gene_expression of Ide 79 0.70 45.04 4.47 99.58
170 INT276874 Localization of Ppargc1a 3 0.73 2.28 0.49 99.58
171 INT3217 Regulation of Ins1 154 0.62 87.11 27.29 99.56
172 INT199330 Regulation of Pck1 3 0.57 3.12 0 99.56
173 INT240835 Regulation of Gene_expression of Pck1 1 0.47 0.59 0 99.56
174 INT240854 Positive_regulation of Regulation of Pck1 1 0.36 0.59 0 99.56
175 INT240843 Regulation of G6pc 3 0.50 1.01 0 99.56
176 INT5806 Regulation of Edn1 63 0.62 23.46 13.88 99.56
177 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 99.54
178 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48 99.54
179 INT297865 Positive_regulation of Gene_expression of Insig1 2 0.21 0.4 0.28 99.54
180 INT133876 Positive_regulation of Gene_expression of Ros1 141 0.32 75.55 27.45 99.52
181 INT5506 Positive_regulation of Gene_expression of Pomc 132 0.70 26.78 54.3 99.52
182 INT159425 Positive_regulation of Cd320 11 0.67 9.35 0.11 99.52
183 INT39415 Gene_expression of HBN1 33 0.43 19.31 0.93 99.52
184 INT339751 Gene_expression of TRO 1 0.21 4.57 0.45 99.52
185 INT293293 Regulation of Marcksl1 1 0.23 0.18 0 99.52
186 INT20286 Positive_regulation of Dob2 16 0.24 5.04 0.41 99.50
187 INT89401 Negative_regulation of Phosphorylation of AKT1 68 0.58 35.61 2.8 99.50
188 INT10872 Regulation of Dob2 5 0.20 2.06 0.25 99.50
189 INT99059 Positive_regulation of Cpb1 16 0.45 3.12 4.09 99.50
190 INT203007 Regulation of Cpb1 4 0.39 1.17 0.23 99.50
191 INT9491 Positive_regulation of Ptpn6 11 0.51 2.33 7.32 99.50
192 INT96911 Positive_regulation of Phosphorylation of Mapk14 46 0.70 43.03 15.15 99.48
193 INT110025 Positive_regulation of Positive_regulation of Mapk14 39 0.63 20.67 12.71 99.48
194 INT246767 Phosphorylation of Ogg1 1 0.73 3.57 0.04 99.48
195 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35 99.48
196 INT287529 Negative_regulation of Positive_regulation of AKR1B1 2 0.41 2.1 0.63 99.48
197 INT76855 Negative_regulation of Gene_expression of PRKCA 4 0.30 1.8 0.36 99.48
198 INT321426 Negative_regulation of Gene_expression of RENBP 1 0.03 0.81 0.05 99.48
199 INT28001 Gene_expression of Gpm6a 23 0.66 16.66 21.09 99.48
200 INT115528 Binding of Ros1 37 0.41 22.96 5.5 99.48
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