D:Hyperhomocysteinemia

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Disease Term
Synonyms Hyperhomocysteinemias
Documents 145
Hot Single Events 128
Hot Interactions 6

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hyperhomocysteinemia. They are ordered first by their relevance to Hyperhomocysteinemia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT127322 Gpx3 Regulation of Mapk1 1 0.00 0.27 0.21 92.88
2 INT127321 Gpx3 Regulation of Mapk3 1 0.00 0.27 0.2 92.52
3 INT127320 Gpx3 Regulation of Akt1 2 0.00 3.11 0.53 92.28
4 INT174266 TNF Regulation of Gene_expression of F3 1 0.00 3.2 0.33 91.56
5 INT174265 IL18 Regulation of Gene_expression of F3 1 0.00 3.21 0.33 91.56
6 INT188789 Binding of pad and Mthfr 1 0.06 4.6 0.31 81.44
7 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 71.92
8 INT326514 Sugt1 Negative_regulation of MTHFR 1 0.01 0.77 0.42 67.20
9 INT266103 Binding of COMT and SNRNP70 1 0.04 0.78 0.21 62.08
10 INT259716 Loxl1 Regulation of Loxl1 1 0.00 1.84 0.08 56.72
11 INT172816 Crp Positive_regulation of Transcription of Nos3 1 0.06 0.91 0.1 53.56
12 INT172817 Crp Positive_regulation of Regulation of Nos3 1 0.09 0.84 0.1 53.56
13 INT172819 Crp Positive_regulation of Gene_expression of Nos3 1 0.06 0.91 0.1 53.56
14 INT172821 Crp Positive_regulation of Negative_regulation of Nos3 1 0.06 0.84 0.1 53.56
15 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12 48.96
16 INT287494 CRP Positive_regulation of Gene_expression of CCL2 2 0.30 2.33 0.83 48.96
17 INT325028 TNF Negative_regulation of Ptgs1 1 0.00 1.79 0.23 22.88
18 INT325008 TNF Negative_regulation of Gene_expression of NOSTRIN 1 0.00 1.78 0.23 22.88
19 INT325007 TNF Negative_regulation of NOSTRIN 1 0.00 1.78 0.23 22.88
20 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
21 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 5.00
22 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59 5.00
23 INT326509 Binding of ACE and VWF 1 0.05 2.07 1.59 5.00
24 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4 5.00
25 INT254355 PF4 Positive_regulation of IFNA1 1 0.04 1.23 1.26 5.00
26 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98 5.00
27 INT187290 Binding of HEY1 and Gtf3a 1 0.00 6.18 0.83 5.00
28 INT266102 Binding of PITX2 and RS1 1 0.00 0.64 0.8 5.00
29 INT188531 Binding of TNF and PDXK 1 0.03 1.99 0.78 5.00
30 INT266100 Binding of COMT and SH2B2 1 0.25 1.22 0.74 5.00
31 INT266108 Binding of COMT and HPS1 1 0.23 1.21 0.74 5.00
32 INT209859 IL4 Positive_regulation of PPARA 1 0.22 1.66 0.69 5.00
33 INT254352 Binding of CXCR4 and Positive_regulation of Gene_expression of CXCL12 1 0.14 1.8 0.66 5.00
34 INT209854 IL4 Positive_regulation of Gene_expression of CD36 1 0.51 1.2 0.65 5.00
35 INT191494 IL6 Positive_regulation of Binding of CRP 1 0.02 1.65 0.65 5.00
36 INT172825 Binding of Crp and T2dm2 1 0.00 4.5 0.62 5.00
37 INT294708 CRP Positive_regulation of Gene_expression of VCAM1 2 0.31 1.92 0.56 5.00
38 INT351332 Positive_regulation of Il4 Positive_regulation of Gene_expression of Il10 1 0.09 1.78 0.53 5.00
39 INT254356 Binding of IFNG and IL1B 1 0.00 1.87 0.51 5.00
40 INT254357 Binding of IFNA1 and IL1B 1 0.00 1.88 0.51 5.00
41 INT209869 Binding of fc and TRMT2A 1 0.00 0 0.51 5.00
42 INT334901 LDLR Positive_regulation of Crp 1 0.00 1.48 0.51 5.00
43 INT176010 Binding of MTHFR and ZNF677 1 0.00 0.7 0.5 5.00
44 INT254348 Binding of ANGPT1 and TEK 1 0.04 1.72 0.48 5.00
45 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46 5.00
46 INT254347 FASLG Negative_regulation of Gene_expression of CHI3L1 1 0.13 0.92 0.42 5.00
47 INT254350 FASLG Negative_regulation of Gene_expression of VEGFA 1 0.06 0.92 0.42 5.00
48 INT209858 TNF Regulation of Transcription of CD36 1 0.27 0 0.4 5.00
49 INT191493 Binding of AGTR1 and NLRP3 2 0.03 2.35 0.39 5.00
50 INT188427 IL6 Positive_regulation of Pdxp 1 0.00 0.84 0.38 5.00
51 INT176009 Binding of GRHPR and ZNF677 1 0.00 0.57 0.36 5.00
52 INT209847 IL4 Positive_regulation of PPARA Positive_regulation of Gene_expression of CD36 1 0.22 0.83 0.34 5.00
53 INT209855 NFE2L2 Positive_regulation of Gene_expression of CD36 1 0.27 0.72 0.32 5.00
54 INT172822 Binding of Fga and T2dm2 1 0.01 2.24 0.31 5.00
55 INT191499 CMA1 Positive_regulation of NLRP3 1 0.02 0.42 0.3 5.00
56 INT191502 Binding of CMA1 and NLRP3 1 0.01 0.42 0.3 5.00
57 INT191501 NLRP3 Positive_regulation of ECE1 1 0.01 1.09 0.28 5.00
58 INT191505 NLRP3 Positive_regulation of Protein_catabolism of EDN1 1 0.00 1.1 0.28 5.00
59 INT182499 Binding of AGTR1 and AGTR2 3 0.20 2.79 0.28 5.00
60 INT294709 IRF6 Positive_regulation of Gene_expression of CCL2 1 0.08 0.14 0.28 5.00
61 INT254353 Binding of VEGFA and MMRN1 1 0.00 0.81 0.28 5.00
62 INT191495 NLRP3 Positive_regulation of Protein_catabolism of ECE1 1 0.01 1.09 0.28 5.00
63 INT191503 CD40LG Regulation of Gene_expression of F3 1 0.01 0.99 0.27 5.00
64 INT191497 Binding of REN and NLRP3 1 0.02 0.55 0.27 5.00
65 INT191504 CPN2 Positive_regulation of NLRP3 1 0.00 0.37 0.27 5.00
66 INT254359 IL1B Positive_regulation of Localization of VEGFA 1 0.01 0.87 0.26 5.00
67 INT191498 Binding of CTSG and NLRP3 1 0.07 0.37 0.25 5.00
68 INT209849 TNF Positive_regulation of Gene_expression of CD36 1 0.69 0.18 0.25 5.00
69 INT191496 CTSG Positive_regulation of NLRP3 1 0.09 0.37 0.25 5.00
70 INT191500 ACE Positive_regulation of Localization of KNG1 1 0.10 0.17 0.24 5.00
71 INT191536 Klk1c2 Positive_regulation of NLRP3 1 0.02 0.36 0.24 5.00
72 INT191537 Binding of Klk1c2 and NLRP3 1 0.02 0.36 0.24 5.00
73 INT191492 Binding of AGT and NLRP3 1 0.01 0.35 0.23 5.00
74 INT254349 Positive_regulation of Binding of EPAS1 and HIF1A 1 0.00 0.92 0.23 5.00
75 INT254351 Binding of ANGPT2 and TEK 1 0.04 0.87 0.22 5.00
76 INT209856 IL1A Negative_regulation of Transcription of CD36 1 0.26 0.1 0.22 5.00
77 INT209848 TNF Positive_regulation of CD36 1 0.46 0.24 0.22 5.00
78 INT172826 Binding of Tnfsf4 and T2dm2 1 0.00 5.97 0.22 5.00
79 INT209851 TGFB2 Negative_regulation of Gene_expression of CD36 1 0.16 0.16 0.21 5.00
80 INT209857 IL10 Negative_regulation of Gene_expression of CD36 1 0.31 0.16 0.2 5.00
81 INT285979 Ros1 Positive_regulation of Trib3 2 0.02 2.18 0.2 5.00
82 INT209850 IL4 Positive_regulation of Gene_expression of PPARA 1 0.18 0.23 0.19 5.00
83 INT228984 CRP Positive_regulation of IL6 2 0.63 0.99 0.17 5.00
84 INT172829 Binding of Nfkb1 and ISYNA1 1 0.00 2.06 0.17 5.00
85 INT172820 Binding of Nfkb1 and T2dm2 1 0.00 2.14 0.17 5.00
86 INT266101 Binding of HPS1 and SH2B2 1 0.17 0.67 0.16 5.00
87 INT172827 ROS1 Positive_regulation of Tnf 1 0.01 2.1 0.16 5.00
88 INT172837 ROS1 Positive_regulation of Nfkb1 1 0.00 2.11 0.16 5.00
89 INT266107 Binding of MET and SH2B2 1 0.02 0.67 0.15 5.00
90 INT332689 Binding of Edn1 and Ros1 1 0.08 0.71 0.14 5.00
91 INT332687 Ros1 Positive_regulation of Crk 1 0.17 0.77 0.12 5.00
92 INT332685 Trib3 Positive_regulation of Binding of Ros1 1 0.01 0.74 0.12 5.00
93 INT172824 Positive_regulation of Binding of Tnfsf4 and T2dm2 1 0.00 2.97 0.12 5.00
94 INT172818 Binding of T2dm2 and Hypism 1 0.00 3.62 0.1 5.00
95 INT332688 Ros1 Positive_regulation of Binding of Edn1 1 0.10 0.57 0.09 5.00
96 INT294711 CRP Regulation of CCL2 1 0.12 0 0.09 5.00
97 INT294712 CRP Regulation of IL6 1 0.41 0 0.09 5.00
98 INT172836 Binding of INS and T2dm2 1 0.00 1.65 0.08 5.00
99 INT245985 Binding of MTR and Mtrr 1 0.06 0.8 0.07 5.00
100 INT279652 PPARA Positive_regulation of Gene_expression of Apoa1 1 0.00 0.75 0.07 5.00
101 INT193954 Binding of App and Psen1 3 0.38 0.88 0.06 5.00
102 INT245986 MTR Regulation of Mthfr 1 0.07 0.18 0.05 5.00
103 INT245981 Negative_regulation of TCN1 Regulation of Mthfr 1 0.03 0.18 0.05 5.00
104 INT245984 TCN1 Regulation of Mtrr 1 0.02 0.18 0.05 5.00
105 INT245966 TCN1 Regulation of MTR 1 0.02 0.18 0.05 5.00
106 INT245982 TCN1 Regulation of Mthfr 1 0.04 0.18 0.05 5.00
107 INT245983 Negative_regulation of TCN1 Regulation of Mtrr 1 0.02 0.18 0.05 5.00
108 INT245967 Negative_regulation of TCN1 Regulation of MTR 1 0.02 0.18 0.05 5.00
109 INT245974 Mtrr Regulation of Mthfr 1 0.07 0.18 0.05 5.00
110 INT325027 Apoc3 Negative_regulation of Pnlip 1 0.01 1.02 0.04 5.00
111 INT332684 Binding of Edn1 and Lep 1 0.09 1.11 0.04 5.00
112 INT325026 Apoc3 Negative_regulation of Lpl 1 0.03 1.01 0.04 5.00
113 INT325025 Apoa2 Positive_regulation of Hdl1 1 0.05 1.03 0.04 5.00
114 INT245987 Binding of MTR and Mthfr 1 0.11 0.48 0.03 5.00
115 INT266105 SH2B2 Positive_regulation of Gene_expression of HPS1 1 0.24 0.62 0.03 5.00
116 INT172832 Binding of ROS1 and Renbp 1 0.00 0.83 0.03 5.00
117 INT352175 USE1 Regulation of NAGA 1 0.01 0.33 0 5.00
118 INT172759 INS Positive_regulation of Localization of REN 1 0.03 0.64 0 5.00
119 INT272300 Binding of LPA and PLG 1 0.09 0.66 0 5.00
120 INT272301 Negative_regulation of Binding of LPA and PLG 1 0.08 0.68 0 5.00
121 INT172838 Binding of ISL1 and T2dm2 1 0.00 2.41 0 5.00
122 INT172831 Binding of INS and Tnfsf4 1 0.02 1.07 0 5.00
123 INT172830 INS Positive_regulation of Agtrap 1 0.01 1.17 0 5.00
124 INT172839 Binding of ANGPT2 and T2dm2 1 0.00 1.72 0 5.00
125 INT175246 Binding of F13A1 and SH2B2 1 0.00 2.24 0 5.00
126 INT172828 Iapp Positive_regulation of Localization of REN 1 0.02 0.64 0 5.00
127 INT172835 Binding of AGT and T2dm2 1 0.00 1.73 0 5.00
128 INT172833 Binding of FFAR1 and T2dm2 1 0.00 1.55 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hyperhomocysteinemia. They are ordered first by their pain relevance and then by number of times they were reported in Hyperhomocysteinemia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT9650 Gene_expression of LPA 141 0.75 104.57 29 100.00
2 INT100861 Binding of CRP 179 0.48 175.2 26.45 100.00
3 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 100.00
4 INT84180 Binding of F5 22 0.48 18.6 0.49 100.00
5 INT147098 Gene_expression of ECA1 4 0.15 2.83 0.48 100.00
6 INT92248 Negative_regulation of F5 7 0.43 3.28 0.4 99.96
7 INT308238 Binding of Prm3 2 0.05 1.3 0.2 99.90
8 INT109881 Positive_regulation of Gene_expression of F8 11 0.47 12.97 1.54 99.88
9 INT2921 Positive_regulation of F8 53 0.59 41.56 8.56 99.88
10 INT68373 Negative_regulation of FLNA 59 0.57 60.46 9.55 99.82
11 INT9842 Binding of F2 36 0.47 22.79 4.42 99.76
12 INT10889 Gene_expression of F8 60 0.78 41.36 5.06 99.70
13 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 99.62
14 INT55878 Regulation of Gene_expression of CCL2 34 0.62 15.71 17.97 99.62
15 INT332683 Positive_regulation of Gene_expression of Ddah1 1 0.12 1.75 0.05 99.60
16 INT332682 Gene_expression of Ddah1 1 0.13 1.75 0.05 99.60
17 INT329023 Positive_regulation of Cbs 1 0.18 1.36 0.07 99.54
18 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.42
19 INT172795 Negative_regulation of Tbca 1 0.00 0.83 0.17 99.38
20 INT39712 Binding of pad 82 0.48 110.92 10.33 99.28
21 INT43985 Regulation of LPA 29 0.62 20.79 3.29 99.28
22 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 99.26
23 INT109448 Negative_regulation of MTHFR 8 0.58 7.62 3.11 99.24
24 INT3128 Negative_regulation of PON1 30 0.59 26.19 4.57 99.10
25 INT111009 Negative_regulation of Tcm 5 0.45 1.73 0.57 98.92
26 INT3723 Binding of PON1 9 0.46 5.83 2.13 98.90
27 INT135629 Binding of COMT 33 0.48 16.68 19.37 98.86
28 INT113606 Positive_regulation of Gene_expression of Mmp9 46 0.64 44 15.07 98.80
29 INT81444 Positive_regulation of Gene_expression of Vcam1 40 0.70 46.38 8.58 98.80
30 INT92129 Positive_regulation of Gene_expression of F3 13 0.08 12.13 2.02 98.80
31 INT174589 Negative_regulation of GLG1 37 0.58 32.41 5.44 98.68
32 INT59302 Positive_regulation of POR 19 0.49 15.18 1.95 98.64
33 INT191529 Negative_regulation of Positive_regulation of POR 1 0.02 1.5 0 98.64
34 INT73670 Gene_expression of Vcam1 128 0.78 123.79 24.96 98.62
35 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 98.62
36 INT18677 Gene_expression of F3 50 0.65 30.86 5.86 98.62
37 INT164010 Gene_expression of CNBP 7 0.53 9.13 1.71 97.94
38 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 97.88
39 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 97.84
40 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 97.48
41 INT1756 Negative_regulation of DNAH8 105 0.59 42.73 20.24 97.40
42 INT121954 Binding of Mthfr 17 0.44 13.47 4.66 97.04
43 INT123536 Positive_regulation of MTHFR 7 0.57 4.74 1 96.92
44 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94 96.88
45 INT591 Negative_regulation of Serpinc1 44 0.57 31.73 8.82 96.44
46 INT5180 Binding of Serpinc1 27 0.36 13.39 2.47 96.44
47 INT106745 Localization of CRP 65 0.81 66.44 15.21 96.34
48 INT176618 Gene_expression of HEY1 29 0.59 36 4.37 96.12
49 INT187288 Positive_regulation of Gene_expression of HEY1 5 0.17 8.42 0.89 96.12
50 INT11030 Binding of LPA 70 0.48 40.35 4.81 96.08
51 INT124996 Regulation of Gpx3 4 0.23 1.54 1.34 95.96
52 INT188418 Binding of Pdxk 3 0.21 2.23 0.59 95.84
53 INT60034 Positive_regulation of VWF 40 0.68 30.42 8.15 95.68
54 INT81965 Gene_expression of F5 16 0.65 13.29 0.48 95.64
55 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 95.04
56 INT92520 Regulation of Elk1 7 0.12 0.27 2.75 94.56
57 INT246551 Negative_regulation of Serpinb12 1 0.01 2.57 0.17 94.48
58 INT174588 Gene_expression of GLG1 16 0.67 11.45 2.03 94.44
59 INT170138 Positive_regulation of Regulation of IL8 2 0.22 0.89 0.04 94.32
60 INT138652 Negative_regulation of Mthfr 13 0.54 7.3 2.88 94.24
61 INT245978 Positive_regulation of Protein_catabolism of TPMT 1 0.03 1.79 0.15 94.00
62 INT245980 Protein_catabolism of TPMT 1 0.04 0.89 0.07 94.00
63 INT12250 Negative_regulation of Mtr 19 0.50 6.9 5.35 93.80
64 INT10835 Regulation of IL8 79 0.49 53.04 24.14 93.24
65 INT170737 Localization of Acsl1 5 0.20 3.51 0.38 92.72
66 INT170740 Localization of Scd1 1 0.17 0.99 0 92.72
67 INT15684 Positive_regulation of Serpine1 65 0.70 43.51 13.67 92.64
68 INT87451 Positive_regulation of Mapk3 34 0.67 12.82 10.38 92.52
69 INT78515 Negative_regulation of Mag 10 0.54 9.4 5.06 92.44
70 INT569 Negative_regulation of C4a 13 0.42 9.48 2.85 92.44
71 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 92.28
72 INT10162 Positive_regulation of Gpx3 10 0.40 3.37 3.68 92.04
73 INT59870 Gene_expression of F3 51 0.65 51.83 14.01 91.56
74 INT99550 Regulation of FLNA 51 0.54 27.88 2.58 91.32
75 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55 91.28
76 INT49103 Positive_regulation of Vcam1 71 0.69 59.52 19.85 91.28
77 INT308240 Gene_expression of Prm3 1 0.06 3.69 0.09 91.28
78 INT104756 Gene_expression of ACSM3 8 0.58 8.76 1.83 91.28
79 INT266129 Gene_expression of AHCYL1 1 0.28 0.85 0.28 91.28
80 INT121513 Positive_regulation of A4GALT 21 0.63 16.06 1.59 91.20
81 INT353029 Regulation of Negative_regulation of LPA 1 0.03 0.69 0 91.12
82 INT11957 Negative_regulation of LPA 52 0.59 39.09 6.84 90.92
83 INT46087 Regulation of F3 4 0.45 3.49 0.68 90.48
84 INT207852 Positive_regulation of Olr1 9 0.12 9.76 2.26 90.44
85 INT159946 Gene_expression of Mat1a 23 0.77 15.33 7.49 90.36
86 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 89.80
87 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37 89.68
88 INT170163 Negative_regulation of ACSM3 5 0.16 3.56 0.96 89.56
89 INT112837 Regulation of GPX1 3 0.17 1.81 0.25 89.28
90 INT95788 Positive_regulation of Positive_regulation of Mapk1 83 0.69 24.75 25.84 89.20
91 INT82660 Negative_regulation of OTOR 3 0.38 1.6 0.69 89.04
92 INT138833 Binding of MTHFR 12 0.46 16.08 6.4 88.28
93 INT110638 Negative_regulation of COMT 43 0.59 21.03 21.05 88.00
94 INT188541 Positive_regulation of Binding of PDXK 1 0.05 0.79 0.23 87.44
95 INT39059 Binding of PDXK 2 0.31 1.37 0.65 87.16
96 INT55880 Negative_regulation of Gene_expression of CCL2 49 0.59 22.37 18.09 86.80
97 INT96851 Negative_regulation of Localization of CCL2 14 0.53 5.98 4.57 86.80
98 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 85.76
99 INT65698 Localization of CCL2 118 0.81 77.54 32.69 85.64
100 INT112562 Binding of SELP 11 0.34 6.25 1.44 85.04
101 INT174271 Binding of F3 6 0.15 6.85 0.53 85.04
102 INT282435 Positive_regulation of Binding of Ahcy 1 0.09 1.09 0.11 85.00
103 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 84.96
104 INT45613 Positive_regulation of pad 23 0.50 24.18 4.8 84.96
105 INT14447 Localization of F2 20 0.79 12.77 2.67 84.56
106 INT22450 Gene_expression of GPI 31 0.58 18.77 6.71 84.52
107 INT253594 Binding of Ahcy 3 0.07 2.8 0.38 84.48
108 INT188422 Negative_regulation of Pdxk 1 0.01 8.91 3.73 84.32
109 INT58288 Positive_regulation of Gene_expression of Crp 83 0.61 82.23 23.7 84.28
110 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 84.24
111 INT124063 Gene_expression of MTHFR 9 0.65 6.22 2.67 84.16
112 INT55335 Binding of Cpox 49 0.34 15.48 18.46 83.92
113 INT124835 Positive_regulation of Nr1i3 7 0.28 2.87 1.23 83.88
114 INT15941 Negative_regulation of Serpine1 42 0.58 21.07 4.95 82.92
115 INT9146 Gene_expression of FOLH1 26 0.75 10.76 2.85 82.92
116 INT69439 Regulation of ROS1 46 0.45 31.22 6.94 82.68
117 INT17101 Positive_regulation of Gene_expression of Edn1 24 0.69 24.9 8.86 82.64
118 INT62546 Positive_regulation of Gene_expression of Icam1 60 0.70 59.52 16.9 82.64
119 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43 82.20
120 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 82.20
121 INT9649 Positive_regulation of LPA 105 0.69 74.75 13.89 82.12
122 INT62822 Positive_regulation of Gene_expression of SELE 22 0.66 28.04 4.97 81.88
123 INT112336 Binding of Serpine1 8 0.41 4.62 0.78 81.84
124 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 81.36
125 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4 81.36
126 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92 81.36
127 INT119396 Regulation of Positive_regulation of Mapk1 22 0.61 7.88 12.25 80.20
128 INT172796 Regulation of Negative_regulation of Nos3 1 0.16 1.4 0.23 80.20
129 INT39948 Binding of FLNA 45 0.42 58.05 4.27 80.00
130 INT53020 Positive_regulation of ACSM3 9 0.58 11.03 2.73 79.60
131 INT65246 Negative_regulation of Nos3 36 0.50 25.65 7.62 79.24
132 INT98992 Binding of Vcam1 13 0.34 12.97 1.04 78.64
133 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 78.56
134 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 78.40
135 INT76532 Binding of Nos3 13 0.37 9.32 1.87 78.24
136 INT170738 Binding of Icam1 23 0.37 25.49 4.09 78.20
137 INT71478 Positive_regulation of Positive_regulation of Prkaca 21 0.37 5.14 8.85 78.16
138 INT222005 Regulation of HPS1 2 0.33 3.3 0.6 78.04
139 INT266126 Regulation of SH2B2 1 0.30 0.84 0.27 78.04
140 INT4683 Negative_regulation of PDXK 17 0.55 12.81 4.39 77.52
141 INT127314 Positive_regulation of Camk2b 1 0.20 0.19 0.3 77.00
142 INT133846 Binding of NPPB 14 0.42 11.52 0.98 76.96
143 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 76.80
144 INT26462 Gene_expression of DNAH8 44 0.78 19.36 7.31 76.56
145 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 76.20
146 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 76.20
147 INT15898 Positive_regulation of Prkaca 199 0.70 50.89 87.54 76.04
148 INT142908 Localization of FGFR1 18 0.38 11.46 2.57 75.84
149 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 75.72
150 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 75.72
151 INT166274 Gene_expression of EPHB1 14 0.55 8.2 1.19 75.20
152 INT21545 Regulation of DNAH8 22 0.59 8.67 6.48 75.00
153 INT108433 Negative_regulation of Mat1a 16 0.57 14.15 2.82 74.20
154 INT11360 Localization of SERPINE1 41 0.80 33.98 5.61 74.16
155 INT48721 Negative_regulation of Localization of SERPINE1 3 0.43 2.4 0.38 74.16
156 INT95790 Regulation of Mapk1 55 0.61 21.17 16.31 73.88
157 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 72.72
158 INT16445 Gene_expression of IL1A 60 0.78 44.46 19.19 72.72
159 INT242910 Positive_regulation of Positive_regulation of Bcl2a1c 2 0.05 2.24 0.06 72.16
160 INT240787 Positive_regulation of Bcl2a1c 12 0.22 9.79 0.06 72.16
161 INT282437 Negative_regulation of Ahcy 1 0.09 3.42 0.08 71.60
162 INT519 Negative_regulation of Comt 52 0.59 17.65 20.39 70.88
163 INT205893 Gene_expression of Ahcy 8 0.63 7.01 1.95 70.44
164 INT2871 Positive_regulation of Comt 9 0.50 2.8 4.78 70.08
165 INT142049 Regulation of Mthfr 6 0.41 4.73 2 69.16
166 INT26194 Regulation of MTR 1 0.19 1.1 0.33 68.92
167 INT245972 Regulation of Mtrr 1 0.21 1.1 0.06 68.92
168 INT41313 Gene_expression of Gpx1 68 0.78 34.24 11.77 68.88
169 INT159947 Negative_regulation of Gene_expression of Mat1a 2 0.42 4.01 1.46 68.48
170 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68 68.28
171 INT37661 Negative_regulation of SERPINC1 48 0.59 38.6 4.77 68.28
172 INT29743 Negative_regulation of App 91 0.59 65.56 31.26 67.80
173 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35 67.64
174 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 67.28
175 INT135291 Positive_regulation of Positive_regulation of Mapk8 24 0.64 19.37 5.16 66.84
176 INT172815 Gene_expression of Cand1 4 0.65 1.86 0.12 66.64
177 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 66.44
178 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2 66.32
179 INT172814 Localization of Cand1 2 0.73 0.96 0.03 65.76
180 INT210391 Negative_regulation of FUT1 5 0.20 5.51 0.23 65.00
181 INT83198 Positive_regulation of Nos3 78 0.64 35.69 17.71 64.04
182 INT193491 Negative_regulation of Positive_regulation of Nos3 2 0.36 1.67 0.4 64.04
183 INT69436 Negative_regulation of Gene_expression of ROS1 81 0.38 46.58 12.22 63.20
184 INT173587 Protein_catabolism of COL5A2 59 0.32 32.73 8.96 62.64
185 INT170260 Regulation of Gene_expression of SELP 3 0.21 2.67 0.11 62.44
186 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48 62.40
187 INT122812 Gene_expression of SNRNP70 130 0.75 67 12.5 62.08
188 INT256622 Regulation of Positive_regulation of Ldha 1 0.08 0.9 0.06 61.28
189 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 61.16
190 INT277909 Negative_regulation of Gene_expression of PIGA 1 0.41 1.17 0 60.88
191 INT277911 Gene_expression of PIGA 1 0.65 1.16 0 60.88
192 INT277910 Positive_regulation of Gene_expression of PIGA 1 0.49 1.17 0 60.88
193 INT63425 Positive_regulation of Gene_expression of SELP 23 0.67 15.34 3.48 60.84
194 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 60.76
195 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43 60.56
196 INT49142 Gene_expression of SELP 94 0.75 54.61 11.64 60.44
197 INT35536 Negative_regulation of CAT 26 0.57 14.39 5.38 59.92
198 INT61513 Positive_regulation of Gpx1 71 0.64 37.91 17.07 59.24
199 INT158542 Gene_expression of HTN1 10 0.75 10.69 1.07 59.04
200 INT328535 Localization of Nacc1 1 0.15 0.68 0 58.72
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