D:Hyperlipidemia

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Disease Term
Synonyms Elevated Ldl, Elevated Vldl, EXOGENOUS HYPERTRIGLYCERIDAEMIA, Exogenous Hypertriglyceridemia, Hypercholesterolaemia, HYPERCHOLESTEROLEMIA, HYPERLIPEMIA, Hyperlipemias, Hyperlipidaemia, Hyperlipidemia Dyslipidemia, Hyperlipidemia Dyslipidemia Hypertension
Documents 2497
Hot Single Events 200
Hot Interactions 67

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hyperlipidemia. They are ordered first by their relevance to Hyperlipidemia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT308643 Binding of Proc and Renbp 1 0.00 1.61 0 100.00
2 INT182818 EEF1A2 Negative_regulation of STAR 1 0.01 1.48 0 100.00
3 INT213144 TIMP1 Negative_regulation of THBD 1 0.04 1.16 0.12 100.00
4 INT213147 DAK Negative_regulation of THBD 1 0.00 1.16 0.12 100.00
5 INT284519 NOVA2 Positive_regulation of Gene_expression of CX3CL1 1 0.07 1.49 0.2 99.82
6 INT127966 GPT Positive_regulation of SLC17A5 1 0.50 1.81 0.14 99.76
7 INT274385 Binding of ABAT and CDIPT 1 0.00 1.21 0 97.24
8 INT299954 Negative_regulation of LXN Negative_regulation of FTSJ3 1 0.00 0.75 0.05 96.40
9 INT350257 Slc12a6 Negative_regulation of Pnlip 1 0.03 1.53 0.03 96.20
10 INT342170 Insr Regulation of Localization of Cd320 1 0.08 0.92 0.04 95.88
11 INT348786 Tlr4 Positive_regulation of Mapk8 1 0.33 1.09 0.11 95.72
12 INT305270 Lep Negative_regulation of Localization of Car2 1 0.16 1.28 0 95.20
13 INT300199 PCSK9 Regulation of Gene_expression of LDLR 1 0.13 0.88 0 95.04
14 INT217396 Binding of Abca1 and App 1 0.26 0.83 0 94.88
15 INT353797 Binding of Ldlr and Trf 1 0.04 0.19 0 94.64
16 INT194482 Binding of Rare1 and Hdl1 1 0.00 1.73 0 94.48
17 INT329221 Prkag1 Negative_regulation of Hmgcr 1 0.06 0.48 0 94.44
18 INT297333 Apoe Negative_regulation of Positive_regulation of Tlr4 1 0.10 1.02 0.14 94.28
19 INT297343 Binding of Apoe and Tlr4 1 0.09 0.94 0.14 94.28
20 INT180470 Cdh23 Positive_regulation of Lpl 1 0.06 1.23 0 94.16
21 INT180469 Apo Positive_regulation of Lpl 1 0.04 1.23 0 94.16
22 INT303845 Binding of PON1 and Pon1 1 0.01 1.33 0 93.48
23 INT321981 Dpp4 Regulation of Glp1r 1 0.07 1.06 0 92.84
24 INT321982 Dpp4 Regulation of Gene_expression of Glp1r 1 0.07 1.06 0 92.84
25 INT321976 Dpp4 Regulation of Gcg 1 0.13 1.06 0 92.84
26 INT321977 Dpp4 Regulation of Negative_regulation of Gcg 1 0.13 1.06 0 92.84
27 INT171599 Binding of APOC3 and Sst1 1 0.01 0.68 0 92.56
28 INT239336 Nr1h2 Positive_regulation of Gene_expression of Fas 1 0.07 0.84 0.29 92.56
29 INT187423 MTTP Regulation of Localization of Cd320 1 0.10 0.81 0 92.48
30 INT239344 Nr1h2 Positive_regulation of Gene_expression of Srebf1 1 0.26 0.84 0.29 92.16
31 INT239329 Nr1h2 Positive_regulation of Gene_expression of Hltf 1 0.04 0.84 0.29 92.16
32 INT262619 Gopc Regulation of Gene_expression of ROS1 1 0.01 0.51 0 91.84
33 INT325027 Apoc3 Negative_regulation of Pnlip 1 0.01 1.02 0.04 90.84
34 INT325026 Apoc3 Negative_regulation of Lpl 1 0.03 1.01 0.04 90.84
35 INT211576 Vldlr Positive_regulation of Lpl 1 0.38 0.24 0 90.56
36 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78 90.48
37 INT302385 Il1b Positive_regulation of Nfib Positive_regulation of Gene_expression of Ccl2 1 0.00 1.48 0.09 90.40
38 INT302380 Tnf Positive_regulation of Nfib 1 0.00 1.41 0.09 90.40
39 INT302383 Il1b Positive_regulation of Nfib 1 0.00 1.42 0.09 90.40
40 INT239347 Nr1h2 Positive_regulation of Srebf1 1 0.26 0.78 0.29 90.00
41 INT165619 Binding of LPL and TGS1 1 0.04 0.61 0.09 89.80
42 INT286444 PCSK9 Positive_regulation of Apob 1 0.02 0.49 0 89.60
43 INT80659 Positive_regulation of INS Positive_regulation of APC 1 0.32 0.65 0 89.48
44 INT239324 Nr1h2 Positive_regulation of Hltf 1 0.04 0.78 0.29 89.20
45 INT80660 INS Positive_regulation of APC 1 0.32 0.65 0 89.12
46 INT351001 Binding of Adh7 and Ins1 1 0.00 1.62 0.05 87.68
47 INT154755 Tnf Positive_regulation of Gene_expression of Ccl2 2 0.23 1.7 0.27 86.88
48 INT288853 Binding of HSD11B1 and LDLR 1 0.26 1.52 0.04 86.20
49 INT302382 Il1b Positive_regulation of Gene_expression of Ccl2 1 0.00 1.39 0.09 85.76
50 INT194485 SNRNP70 Regulation of Ppara 1 0.00 0.53 0 85.28
51 INT173130 Binding of INS and PPARA 2 0.04 1.8 0.08 85.20
52 INT313846 Olr407 Negative_regulation of Lipg 1 0.00 0.55 0.09 84.36
53 INT214472 Binding of LPL and GPIHBP1 1 0.29 1.17 0 84.32
54 INT214473 GPIHBP1 Positive_regulation of Binding of LPL and GPIHBP1 1 0.44 0.58 0 84.32
55 INT235313 Cyp3a23/3a1 Positive_regulation of Ins1 1 0.14 0.82 0.05 84.32
56 INT201512 Binding of PRSS1 and hcp 1 0.09 1.9 0.57 84.04
57 INT301906 Binding of HMOX1 and HSD11B1 1 0.05 2.41 0 83.72
58 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3 82.32
59 INT142332 Binding of SERPINH1 and TNNI3 1 0.03 1.05 0.17 82.16
60 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 81.88
61 INT213034 Hdl1 Positive_regulation of Apc 1 0.08 1.21 0 81.52
62 INT213056 Hdl1 Positive_regulation of Vtn Positive_regulation of Apc 1 0.00 1.21 0 81.52
63 INT213025 Vtn Positive_regulation of Apc 1 0.01 1.19 0 81.52
64 INT213037 Hdl1 Positive_regulation of Gene_expression of Serpine1 1 0.19 1.19 0.04 81.48
65 INT274387 Binding of POLA1 and IGSF9 1 0.01 0.58 0 80.96
66 INT229290 BAS Negative_regulation of LDLR 1 0.03 0.83 0.13 80.80
67 INT171598 Binding of APOB and Lipg 1 0.01 0.63 0 80.76
68 INT182813 EEF1A2 Negative_regulation of ITGAL 1 0.10 1.53 0.51 79.76
69 INT221085 GHRH Positive_regulation of Gene_expression of IGF1 2 0.56 1.47 0.41 78.80
70 INT302384 IL6 Positive_regulation of Localization of Crp 1 0.10 1.39 0.15 78.76
71 INT353802 Binding of APOE and Apob 1 0.05 0.83 0 76.80
72 INT353801 Binding of APOE and Cd320 1 0.22 0.83 0 76.80
73 INT353804 Binding of APOE and Ldlr 1 0.16 0.84 0 76.80
74 INT353803 Binding of APOE and Hdl1 1 0.01 0.83 0 76.80
75 INT197726 Negative_regulation of CETP Positive_regulation of HSD11B1 1 0.11 0.76 0 76.40
76 INT184814 NOS3 Positive_regulation of Gene_expression of NOS1 1 0.09 0.54 0.1 76.36
77 INT353795 Binding of Cd320 and Apob 1 0.08 0.82 0 75.68
78 INT353799 Binding of Cd320 and Hdl1 1 0.03 0.83 0 75.68
79 INT353800 Binding of Ldlr and Cd320 1 0.29 0.83 0 75.68
80 INT227303 Zbp1 Regulation of Transcription of Baat 1 0.09 1.43 0.08 75.68
81 INT227301 Zbp1 Regulation of Transcription of Ucp1 1 0.19 1.42 0.08 75.68
82 INT227304 Zbp1 Regulation of Transcription of Ucp2 1 0.17 1.43 0.08 75.68
83 INT353798 Binding of Hdl1 and Apob 1 0.01 0.82 0 75.48
84 INT353796 Binding of Ldlr and Apob 1 0.06 0.82 0 75.48
85 INT171601 INCENP Negative_regulation of Lpl 1 0.01 0.38 0 75.28
86 INT171603 APOC3 Negative_regulation of Lpl 1 0.48 0.38 0 75.28
87 INT182804 Binding of ETV3 and T2DM 1 0.10 2.62 0 75.20
88 INT221402 Binding of INS and LPA 1 0.00 0.63 0 75.08
89 INT253945 Adrm1 Negative_regulation of Hdl1 1 0.00 1.18 0 75.00
90 INT129364 Ea1 Positive_regulation of Localization of Ins1 1 0.02 0.49 0.2 75.00
91 INT171600 INCENP Negative_regulation of Lipg 1 0.00 0.38 0 74.88
92 INT171602 APOC3 Negative_regulation of Lipg 1 0.04 0.38 0 74.88
93 INT279901 Binding of FADS3 and USF1 1 0.35 4.71 0 74.28
94 INT213009 Hdl1 Positive_regulation of Positive_regulation of Apc 1 0.09 1.14 0 73.04
95 INT194486 Binding of SNRNP70 and Apob 1 0.00 0.64 0.03 73.04
96 INT194484 Binding of SNRNP70 and Chol1 1 0.00 0.64 0.03 73.04
97 INT235546 Stat6 Positive_regulation of Positive_regulation of Hand2 1 0.02 0.9 0.14 72.80
98 INT256418 PPARA Positive_regulation of NR1H4 1 0.01 1.17 0.04 72.40
99 INT235544 Binding of Ighm and Olr1 1 0.00 0.68 0.03 72.32
100 INT239335 Eef1a2 Positive_regulation of Ppara 1 0.27 0.57 0.26 72.16
101 INT326997 HSD11B1 Negative_regulation of Hdl2 1 0.12 2.06 0 71.28
102 INT326980 HSD11B1 Negative_regulation of JPH3 1 0.03 2.05 0 71.28
103 INT265956 Clas4 Regulation of PPARA 1 0.01 0.7 0.14 71.00
104 INT326979 HLN2 Negative_regulation of JPH3 1 0.02 2.05 0 70.96
105 INT326996 HLN2 Negative_regulation of Hdl2 1 0.06 2.05 0 70.96
106 INT178334 Binding of Pon1 and Chdh 1 0.11 11.45 0.66 70.72
107 INT329215 Prkag1 Negative_regulation of Acaca 1 0.08 0.26 0 70.32
108 INT317842 Hdlcl1 Positive_regulation of Ldlr 1 0.00 1.11 0 68.68
109 INT329589 Serpina5 Positive_regulation of PTX3 1 0.03 1.52 0.66 67.56
110 INT308663 Apoe Regulation of Car2 1 0.02 0.44 0.07 66.96
111 INT213060 Hdl1 Negative_regulation of Gene_expression of PLEK 1 0.25 1.33 0.05 66.84
112 INT40208 Binding of Eef1a1 and Hils1 1 0.01 0.22 0.42 66.80
113 INT247439 Binding of APOA1 and HSD11B1 3 0.32 5.01 0.03 66.20
114 INT213072 Binding of IFNA1 and ACCS 1 0.06 3.85 0.17 65.96
115 INT199109 Binding of Akt1 and Arhgdia 1 0.02 2.73 0.87 65.12
116 INT258492 Binding of Ins1 and Cdipt 1 0.00 0.92 0 63.72
117 INT240617 Binding of APOB and ADIPOQ 1 0.04 3.62 0.38 63.52
118 INT323278 Dhfr Negative_regulation of Negative_regulation of Igkv1-131 1 0.02 0.93 1.02 63.28
119 INT323280 Dhfr Negative_regulation of Igkv1-131 1 0.02 0.47 0.51 63.28
120 INT194483 Binding of Apoe and Chol1 1 0.24 0.51 0.03 62.88
121 INT194481 Binding of Apoe and Apob 1 0.07 0.51 0.03 62.88
122 INT319735 Positive_regulation of Binding of IL6 and IL8 1 0.01 1.35 0.11 62.52
123 INT297339 Tlr4 Negative_regulation of Gene_expression of Apoe 1 0.10 0.73 0.13 62.32
124 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11 62.12
125 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13 62.08
126 INT187603 Binding of Ptgis and Ppara 1 0.00 0.26 0.31 61.52
127 INT321983 Glp1r Negative_regulation of Localization of Gcg 1 0.09 1.36 0.11 61.44
128 INT332688 Ros1 Positive_regulation of Binding of Edn1 1 0.10 0.57 0.09 61.28
129 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12 60.76
130 INT350256 Slc12a6 Negative_regulation of Positive_regulation of Fabp4 1 0.03 0.56 0 58.00
131 INT350255 Slc12a6 Negative_regulation of Transcription of Fabp4 1 0.03 0.56 0 58.00
132 INT254774 DNMT1 Positive_regulation of Localization of Apoe 1 0.01 0.31 0.23 57.60
133 INT182778 IGF1 Positive_regulation of Gene_expression of ETV3 1 0.03 1.89 0 57.20
134 INT182783 INS Positive_regulation of Gene_expression of ETV3 1 0.01 1.89 0 57.20
135 INT182777 IAPP Positive_regulation of Gene_expression of ETV3 1 0.06 1.88 0 57.20
136 INT213007 Hdl1 Regulation of Regulation of Apc 1 0.08 1.24 0 55.92
137 INT213054 Hdl1 Regulation of Apc 1 0.05 1.24 0 55.92
138 INT182784 IGF1 Positive_regulation of Gene_expression of INS 1 0.02 1.87 0 55.44
139 INT182776 IAPP Positive_regulation of Gene_expression of INS 1 0.03 1.87 0 55.44
140 INT230423 INS Negative_regulation of Lipg 1 0.03 0.74 0.03 54.64
141 INT197725 Negative_regulation of CETP Positive_regulation of Positive_regulation of HSD11B1 1 0.11 1.15 0 54.16
142 INT310275 Negative_regulation of Binding of Adipoq and Ins1 1 0.19 1.14 0.09 54.00
143 INT310274 Binding of Adipoq and Ins1 1 0.21 1.14 0.09 54.00
144 INT178336 Binding of SUGT1 and Chdh 1 0.00 0.98 0.17 53.80
145 INT312794 Hdl1 Regulation of Pon1 1 0.02 1.63 0.15 53.28
146 INT323279 Binding of Nos3 and Arg2 1 0.01 0.67 0 52.92
147 INT178351 Binding of Il6 and Hp 1 0.00 0.61 0.14 52.40
148 INT300194 HSD11B1 Negative_regulation of CHDH 1 0.08 2.19 0 52.12
149 INT325285 COMP Positive_regulation of UBR5 1 0.00 2.9 0 51.08
150 INT253944 Positive_regulation of Prkca Positive_regulation of Gene_expression of Ins1 1 0.01 1.53 0.35 50.00
151 INT330620 S100a8 Positive_regulation of Positive_regulation of TNF 1 0.03 1.92 0.32 50.00
152 INT268013 Binding of Nos3 and Acot1 1 0.02 1.48 0 49.04
153 INT305271 Binding of Lep and Obsty1 1 0.06 4.86 0 48.96
154 INT213052 Hdl1 Negative_regulation of Gene_expression of Vwf 1 0.19 1.23 0.04 47.88
155 INT300196 Binding of HSD11B1 and CHDH 1 0.07 4.01 0 47.60
156 INT221814 Mastl Positive_regulation of Ppara 1 0.04 0.68 0.37 47.00
157 INT310200 Binding of Serping1 and F12 1 0.21 0.05 0 46.16
158 INT312768 Pon1 Negative_regulation of Gene_expression of Ccl2 1 0.06 1.42 0.26 45.60
159 INT298082 Regulation of Binding of OVGP1 and Ggt5 1 0.01 0 0 45.32
160 INT274625 OPN1MW Positive_regulation of SOD1 1 0.19 0.29 0.5 45.00
161 INT341309 Binding of Npc1 and Sugt1 1 0.01 1.04 0 44.64
162 INT298081 Binding of OVGP1 and Ggt5 1 0.01 0 0 44.12
163 INT191505 NLRP3 Positive_regulation of Protein_catabolism of EDN1 1 0.00 1.1 0.28 42.48
164 INT325025 Apoa2 Positive_regulation of Hdl1 1 0.05 1.03 0.04 42.08
165 INT230855 KNG1 Regulation of NOS1 2 0.03 0.94 0.33 41.76
166 INT341310 Binding of Npc1 and Chdh 1 0.11 7.04 0 41.36
167 INT183302 Tchol1 Negative_regulation of Lipg 1 0.00 0.52 0.05 41.12
168 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36 40.00
169 INT191495 NLRP3 Positive_regulation of Protein_catabolism of ECE1 1 0.01 1.09 0.28 39.44
170 INT230745 Negative_regulation of Ace Negative_regulation of Icam1 1 0.05 1.22 0.29 39.28
171 INT143993 Prdx2 Positive_regulation of Atp13a4 1 0.00 0 0.05 39.24
172 INT302295 PPARA Regulation of OAS2 1 0.01 0.72 0.17 38.76
173 INT301632 Binding of Dbi and Fabp1 1 0.13 0.49 0.07 38.36
174 INT191501 NLRP3 Positive_regulation of ECE1 1 0.01 1.09 0.28 38.32
175 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 37.84
176 INT332684 Binding of Edn1 and Lep 1 0.09 1.11 0.04 37.44
177 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 37.12
178 INT279894 Binding of USF1 and TGS1 1 0.11 3.52 0 34.96
179 INT279909 Binding of FADS3 and TGS1 1 0.12 6 0 34.96
180 INT191497 Binding of REN and NLRP3 1 0.02 0.55 0.27 34.48
181 INT230852 ACE Regulation of KNG1 2 0.03 0.72 0.32 34.44
182 INT239239 Binding of PPARA and RXRB 1 0.12 0.63 0 32.92
183 INT265934 SREBF1 Positive_regulation of Transcription of SERPINE1 1 0.01 0.62 0 32.72
184 INT349077 Binding of HLA-E and KLRD1 1 0.00 0.16 0 32.48
185 INT201767 Igf1 Positive_regulation of PIK3CG 1 0.00 0.84 0 32.00
186 INT201759 Ngf Positive_regulation of PIK3CG 1 0.01 0.84 0 32.00
187 INT142348 Igf1 Positive_regulation of Akt1 2 0.50 1.16 0.06 31.80
188 INT201730 Ngf Positive_regulation of Akt1 1 0.01 0.84 0 31.80
189 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 31.04
190 INT325028 TNF Negative_regulation of Ptgs1 1 0.00 1.79 0.23 30.56
191 INT192309 Binding of GSTM1 and GSTT1 2 0.43 4.54 0.06 30.56
192 INT307207 Ppara Positive_regulation of Apoa2 1 0.10 0.94 0.25 30.44
193 INT250553 Binding of RS1 and SUGT1 3 0.00 3.36 0.22 29.64
194 INT177358 Ptger1 Positive_regulation of Localization of AMY2A 1 0.00 0.56 0.54 29.28
195 INT177357 Ptger1 Positive_regulation of Gene_expression of AMY2A 1 0.00 0.56 0.54 29.28
196 INT334390 ADIPOQ Positive_regulation of Localization of INS 1 0.09 1.3 0.23 29.08
197 INT325008 TNF Negative_regulation of Gene_expression of NOSTRIN 1 0.00 1.78 0.23 28.88
198 INT325007 TNF Negative_regulation of NOSTRIN 1 0.00 1.78 0.23 28.88
199 INT310276 Gcg Positive_regulation of Localization of Ins1 1 0.25 0 0 28.24
200 INT297330 Apoe Positive_regulation of Gene_expression of Nos2 1 0.26 0.34 0.07 27.36

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hyperlipidemia. They are ordered first by their pain relevance and then by number of times they were reported in Hyperlipidemia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT5164 Negative_regulation of Ldlr 83 0.58 55.01 7.87 100.00
2 INT3002 Binding of SUGT1 62 0.24 55.9 14.91 100.00
3 INT17913 Regulation of HSD11B1 87 0.60 93.23 6.04 100.00
4 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05 100.00
5 INT233765 Binding of HAP1 1 0.03 4.11 0.42 100.00
6 INT17086 Binding of HSD11B1 84 0.47 122.28 6.16 100.00
7 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36 100.00
8 INT24643 Gene_expression of Hdlcl1 30 0.73 26.83 1.9 100.00
9 INT63042 Binding of Apoe 59 0.48 31.23 5.88 100.00
10 INT142265 Regulation of Apoe 20 0.60 9.52 2.23 100.00
11 INT28015 Regulation of Cyp3a23/3a1 19 0.40 6.32 5.79 100.00
12 INT212382 Positive_regulation of USF1 2 0.50 3.14 0.27 100.00
13 INT174753 Gene_expression of Apoa2 15 0.75 13.82 0.41 100.00
14 INT4553 Binding of G6PD 7 0.37 3 0.44 100.00
15 INT39271 Positive_regulation of Gene_expression of Hdlcl1 4 0.48 3.97 0.55 100.00
16 INT124250 Binding of APOA4 3 0.18 4.83 0.53 100.00
17 INT57549 Gene_expression of GNPTAB 49 0.65 57.5 9.05 100.00
18 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72 100.00
19 INT32795 Positive_regulation of Hypism 17 0.15 20.16 1.73 100.00
20 INT183635 Negative_regulation of Positive_regulation of Ppara 11 0.42 10 1.2 100.00
21 INT164631 Regulation of Gene_expression of EGFL7 5 0.08 2 0.05 100.00
22 INT284521 Negative_regulation of CX3CL1 11 0.27 13.86 1.87 99.98
23 INT165492 Negative_regulation of Gene_expression of CX3CL1 1 0.20 6.76 0.68 99.98
24 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 99.96
25 INT9650 Gene_expression of LPA 141 0.75 104.57 29 99.96
26 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21 99.96
27 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32 99.96
28 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54 99.96
29 INT94437 Positive_regulation of Gene_expression of OLR1 17 0.70 16.04 2.8 99.96
30 INT39406 Positive_regulation of OLR1 45 0.70 37.8 7.72 99.96
31 INT3970 Positive_regulation of Sord 9 0.70 4.29 3.93 99.96
32 INT39667 Positive_regulation of Positive_regulation of Sord 2 0.18 1.99 0.27 99.96
33 INT134316 Positive_regulation of RT1-Hb-ps1 6 0.32 8.44 1.76 99.96
34 INT197016 Positive_regulation of Gene_expression of LDLR 13 0.50 5.82 0.24 99.96
35 INT254793 Negative_regulation of Gene_expression of Egfl7 3 0.03 3.75 0.07 99.96
36 INT17562 Negative_regulation of Lipg 32 0.51 16.91 3.17 99.92
37 INT151586 Positive_regulation of Prkag1 51 0.54 18.7 3.34 99.92
38 INT256243 Transcription of Egfl7 2 0.06 1.07 0 99.92
39 INT36449 Negative_regulation of G6PD 74 0.59 54.15 8.85 99.92
40 INT2243 Localization of GAST 67 0.81 34.54 16.19 99.92
41 INT2242 Negative_regulation of Localization of GAST 12 0.58 5.55 4.22 99.92
42 INT45176 Negative_regulation of LPL 34 0.59 22.22 2.01 99.90
43 INT142800 Positive_regulation of Ldlr 21 0.68 14.75 0.6 99.90
44 INT9467 Negative_regulation of APOB 14 0.57 10.49 0.88 99.90
45 INT10861 Negative_regulation of Vldlr 5 0.11 3.22 0.27 99.90
46 INT21805 Negative_regulation of Hdlbp 7 0.30 9.66 1.43 99.90
47 INT2432 Positive_regulation of Cp 41 0.67 31.1 16.68 99.90
48 INT58617 Negative_regulation of APOC2 1 0.41 0.83 0 99.90
49 INT40877 Positive_regulation of APOB 35 0.68 32.47 1.86 99.88
50 INT179360 Positive_regulation of HDLBP 5 0.11 5.09 0.39 99.88
51 INT147583 Gene_expression of AIS 82 0.58 48.7 7.11 99.88
52 INT323018 Regulation of PTX3 1 0.27 6.86 1.59 99.88
53 INT9548 Gene_expression of CHKB 99 0.65 50.86 9.03 99.88
54 INT162636 Localization of PTX3 8 0.78 9.73 1.77 99.88
55 INT329588 Positive_regulation of Regulation of PTX3 1 0.47 1.85 0.74 99.88
56 INT241549 Negative_regulation of Gene_expression of AIS 5 0.37 3.72 0.48 99.88
57 INT159425 Positive_regulation of Cd320 11 0.67 9.35 0.11 99.86
58 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 99.84
59 INT4012 Negative_regulation of Psd 23 0.52 14.12 3.81 99.84
60 INT288 Positive_regulation of Sct 88 0.70 32.83 24.5 99.84
61 INT89288 Positive_regulation of Negative_regulation of NOS1 5 0.40 4.84 0.96 99.84
62 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 99.84
63 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 99.84
64 INT27935 Binding of Vim 21 0.36 15.65 2.61 99.84
65 INT166557 Binding of Smc1b 1 0.15 0.27 0.22 99.84
66 INT141502 Positive_regulation of CX3CL1 21 0.55 25.8 8.88 99.82
67 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 99.82
68 INT120827 Regulation of CX3CL1 3 0.14 2.24 2.94 99.82
69 INT178675 Regulation of Gene_expression of CX3CL1 2 0.21 2.96 0.5 99.82
70 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 99.80
71 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.80
72 INT32203 Negative_regulation of Crp 48 0.58 32.77 11.89 99.80
73 INT57360 Gene_expression of STAR 31 0.66 12.72 2.24 99.80
74 INT81575 Gene_expression of SIL1 29 0.25 19.76 1.24 99.80
75 INT9055 Positive_regulation of Cog1 22 0.68 14.08 2.95 99.78
76 INT197737 Positive_regulation of Positive_regulation of HDLBP 1 0.03 1.61 0 99.78
77 INT2578 Binding of Ins1 74 0.48 33.57 12.92 99.76
78 INT299965 Regulation of EPC1 7 0.23 4.44 0.53 99.76
79 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 99.76
80 INT17262 Negative_regulation of Plat 17 0.59 15.14 6.36 99.76
81 INT83193 Binding of Olr1 6 0.42 10 2.43 99.76
82 INT157463 Gene_expression of CX3CL1 55 0.62 69.05 19.75 99.74
83 INT10829 Regulation of Ldlr 12 0.34 8.12 1.35 99.74
84 INT102251 Positive_regulation of Positive_regulation of Crp 24 0.58 29.62 7.5 99.74
85 INT139803 Gene_expression of PTX3 22 0.75 26.21 5.07 99.72
86 INT36142 Negative_regulation of Hmgcr 33 0.46 15.91 3.54 99.70
87 INT57556 Negative_regulation of tch 1 0.21 0.87 0.13 99.70
88 INT37131 Regulation of Localization of SERPINF1 1 0.21 0.24 0.14 99.68
89 INT61423 Gene_expression of Egfl7 23 0.14 24.96 0.66 99.68
90 INT17686 Negative_regulation of Hdl1 72 0.36 81.85 7.74 99.66
91 INT94438 Gene_expression of OLR1 86 0.78 80.38 11.03 99.66
92 INT51750 Positive_regulation of Localization of Cog1 1 0.02 1.39 0.09 99.66
93 INT5913 Binding of OPA1 12 0.41 9.33 2.92 99.64
94 INT243181 Positive_regulation of Gene_expression of EGFL7 3 0.07 1.21 0.77 99.64
95 INT15166 Positive_regulation of Mme 40 0.70 13.01 16.24 99.62
96 INT171597 Gene_expression of APOC3 9 0.77 3.18 0.2 99.60
97 INT171593 Positive_regulation of Gene_expression of APOC3 1 0.69 0.55 0 99.60
98 INT16024 Regulation of Cand1 5 0.60 2.74 1.04 99.58
99 INT212957 Positive_regulation of Localization of Serpine1 2 0.50 1.89 0.15 99.58
100 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04 99.56
101 INT84978 Positive_regulation of CHDH 21 0.50 21.97 0.48 99.56
102 INT207565 Negative_regulation of LIPG 8 0.10 7.83 0.76 99.54
103 INT27639 Negative_regulation of Gene_expression of C9orf3 4 0.57 3.97 0.48 99.52
104 INT17020 Localization of AHSP 11 0.80 3.82 4.34 99.52
105 INT164633 Gene_expression of EGFL7 23 0.53 10.46 3.1 99.50
106 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26 99.48
107 INT198892 Regulation of Binding of Apoe 6 0.45 2.94 0.21 99.48
108 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32 99.46
109 INT170554 Binding of Renbp 17 0.17 12.36 0.45 99.46
110 INT287508 Negative_regulation of COX2 1 0.01 2.17 0.15 99.44
111 INT38299 Negative_regulation of FCGR2C 6 0.21 3.92 0.52 99.42
112 INT47628 Regulation of CEL 9 0.60 4.5 1.85 99.42
113 INT75869 Gene_expression of Acsl1 24 0.45 27.76 3.66 99.40
114 INT23188 Localization of Serpine1 22 0.79 16.06 1.96 99.38
115 INT122561 Negative_regulation of Gene_expression of Adipoq 12 0.56 14.02 2.26 99.38
116 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77 99.38
117 INT146594 Negative_regulation of Gene_expression of LEP 25 0.42 18.88 5.71 99.38
118 INT117499 Negative_regulation of Adipoq 28 0.56 24.15 5.07 99.38
119 INT171594 Binding of APOC3 5 0.37 3.97 0 99.36
120 INT10057 Gene_expression of Ldlr 35 0.67 23.99 3.05 99.32
121 INT4360 Gene_expression of Hypism 29 0.22 38.1 4.07 99.32
122 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 99.32
123 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 99.28
124 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 99.28
125 INT1114 Localization of Ins1 748 0.80 192.95 165.48 99.28
126 INT92822 Negative_regulation of Gene_expression of Crp 36 0.49 29.5 8.83 99.28
127 INT76573 Negative_regulation of Vcam1 26 0.58 24.36 9.84 99.28
128 INT19967 Gene_expression of C9orf3 18 0.75 26.51 4.6 99.24
129 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94 99.24
130 INT208332 Positive_regulation of Apoc3 4 0.29 3.3 0.1 99.24
131 INT181880 Positive_regulation of Apoa1 19 0.66 21.19 2.43 99.24
132 INT168304 Positive_regulation of SNRPB 17 0.25 9.62 1.64 99.24
133 INT190878 Positive_regulation of Gene_expression of Apoc3 3 0.29 2.76 0.3 99.24
134 INT194469 Positive_regulation of Apob 3 0.15 2.29 0.12 99.24
135 INT93913 Positive_regulation of CD40 21 0.58 23.47 3.1 99.24
136 INT100593 Gene_expression of UBAP1 8 0.65 13.81 5.74 99.24
137 INT97830 Binding of Reg3a 2 0.00 1.57 0.8 99.24
138 INT72703 Gene_expression of Ide 79 0.70 45.04 4.47 99.22
139 INT4691 Regulation of Lipg 10 0.61 4.7 1.99 99.22
140 INT2579 Protein_catabolism of Ins1 43 0.99 9.91 5.14 99.22
141 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48 99.20
142 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 99.20
143 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 99.20
144 INT51751 Localization of Cog1 3 0.11 2.8 0.08 99.20
145 INT103094 Binding of PPARA 308 0.47 177.26 34.75 99.16
146 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 99.16
147 INT65245 Gene_expression of Nos3 121 0.78 98.14 41.56 99.16
148 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 99.14
149 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 99.14
150 INT19177 Negative_regulation of GRHPR 19 0.53 12.65 2.71 99.12
151 INT262114 Negative_regulation of Nr1i2 1 0.55 4.72 1.12 99.12
152 INT135407 Negative_regulation of Ccl2 33 0.57 32.74 9.45 99.12
153 INT19966 Positive_regulation of C9orf3 19 0.67 21.88 4.38 99.08
154 INT11062 Positive_regulation of MME 24 0.63 14.37 5.26 99.08
155 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 99.08
156 INT23191 Gene_expression of HDLCQ1 13 0.60 14.39 1.58 99.08
157 INT129425 Negative_regulation of Ldlr 22 0.42 17.15 0.97 99.06
158 INT10858 Negative_regulation of Apol7b 3 0.02 5.28 0.33 99.06
159 INT36263 Positive_regulation of CEL 53 0.69 34.88 12.87 99.04
160 INT66332 Gene_expression of Ucp1 40 0.75 40.09 2.48 99.04
161 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 99.02
162 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 99.02
163 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 99.02
164 INT24644 Regulation of Hdlcl1 18 0.42 15.44 0.91 99.02
165 INT116996 Regulation of Pgp 9 0.51 7.51 8.01 99.02
166 INT44816 Regulation of Serpina6 16 0.62 3.63 8.02 99.02
167 INT8765 Positive_regulation of Cyp3a23/3a1 63 0.67 22.28 20.39 99.00
168 INT17565 Regulation of Gpt 85 0.60 43.64 13.68 99.00
169 INT80656 Regulation of SLC17A5 15 0.26 6.89 3.19 99.00
170 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55 98.98
171 INT174591 Positive_regulation of GLG1 6 0.60 4.63 0.82 98.96
172 INT95271 Negative_regulation of Nos3 46 0.53 24.1 9.71 98.96
173 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58 98.94
174 INT10827 Gene_expression of Apob 16 0.78 13.08 0.9 98.88
175 INT190883 Gene_expression of Apoc3 16 0.38 14.18 1.93 98.88
176 INT181886 Gene_expression of Apoa1 40 0.64 40.53 4.56 98.88
177 INT15921 Positive_regulation of Serpine1 85 0.68 81.24 13.4 98.88
178 INT104624 Negative_regulation of Apoe 26 0.59 19.25 3.71 98.88
179 INT19545 Positive_regulation of IV 5 0.61 4.22 0.83 98.88
180 INT38543 Positive_regulation of Positive_regulation of IV 1 0.44 1.18 0.16 98.88
181 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 98.86
182 INT11030 Binding of LPA 70 0.48 40.35 4.81 98.84
183 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 98.84
184 INT4679 Negative_regulation of RAPGEF5 55 0.57 47.51 4.55 98.84
185 INT10923 Positive_regulation of Lipg 30 0.50 22.87 4.26 98.84
186 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 98.82
187 INT47994 Negative_regulation of Lipg 45 0.50 27.19 7.24 98.82
188 INT217636 Regulation of fa 3 0.05 1.2 0.08 98.82
189 INT6133 Negative_regulation of Serpinc1 56 0.58 42.8 8.35 98.80
190 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 98.80
191 INT167019 Negative_regulation of Gene_expression of Ldlr 3 0.42 0.76 0.08 98.80
192 INT19964 Negative_regulation of Positive_regulation of C9orf3 3 0.42 4.06 0.67 98.80
193 INT56310 Gene_expression of Baat 15 0.44 15.5 1.11 98.80
194 INT10862 Positive_regulation of Vldlr 4 0.15 2.96 0.49 98.76
195 INT200090 Positive_regulation of Gene_expression of Ldlr 5 0.37 3.67 0.59 98.76
196 INT297432 Positive_regulation of Localization of Ldlr 2 0.14 0.35 0.03 98.76
197 INT13608 Negative_regulation of Localization of Ggh 5 0.45 1.97 2.43 98.76
198 INT1000 Localization of Ggh 31 0.75 2.74 16.41 98.76
199 INT219648 Gene_expression of Hd 16 0.27 8.78 0.68 98.72
200 INT57728 Regulation of LDLR 25 0.41 13.18 3.46 98.72
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