D:Hyperlipoproteinemia Type Ii

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Disease Term
Synonyms Apolipoprotein B 100 Familial Ligand Defective, Autosomal Dominant Hypercholesterolemia, COMBINED HYPERLIPOPROTEINEMIA FAMILIAL, ESSENTIAL HYPERCHOLESTEROLEMIA, ESSENTIAL HYPERCHOLESTEROLEMIAS, Familial Combined Hyperlipoproteinemia, Familial Hypercholesterolemia, FAMILIAL HYPERCHOLESTEROLEMIAS, Hyper Low Density Lipoproteinemia, HYPER LOW DENSITY LIPOPROTEINEMIAS, Hyperbetalipoproteinemia
Documents 124
Hot Single Events 128
Hot Interactions 15

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hyperlipoproteinemia Type Ii. They are ordered first by their relevance to Hyperlipoproteinemia Type Ii and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT344644 CIMT Positive_regulation of Positive_regulation of Asap1 1 0.02 0.4 0 100.00
2 INT286444 PCSK9 Positive_regulation of Apob 1 0.02 0.49 0 99.52
3 INT344643 Egfl7 Regulation of CIMT 1 0.00 0.2 0 99.28
4 INT353802 Binding of APOE and Apob 1 0.05 0.83 0 99.10
5 INT353801 Binding of APOE and Cd320 1 0.22 0.83 0 99.10
6 INT353804 Binding of APOE and Ldlr 1 0.16 0.84 0 99.10
7 INT353803 Binding of APOE and Hdl1 1 0.01 0.83 0 99.10
8 INT353795 Binding of Cd320 and Apob 1 0.08 0.82 0 98.54
9 INT353799 Binding of Cd320 and Hdl1 1 0.03 0.83 0 98.54
10 INT353800 Binding of Ldlr and Cd320 1 0.29 0.83 0 98.54
11 INT353798 Binding of Hdl1 and Apob 1 0.01 0.82 0 98.44
12 INT353796 Binding of Ldlr and Apob 1 0.06 0.82 0 98.44
13 INT66590 Gnrhr Regulation of Ldlr 1 0.02 0.4 0.06 98.28
14 INT300199 PCSK9 Regulation of Gene_expression of LDLR 1 0.13 0.88 0 97.68
15 INT353797 Binding of Ldlr and Trf 1 0.04 0.19 0 95.00
16 INT206082 IL6 Positive_regulation of Gene_expression of CCL2 1 0.07 0.3 0 13.52
17 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00
18 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
19 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18 5.00
20 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 5.00
21 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63 5.00
22 INT115186 IL6 Positive_regulation of Phosphorylation of STAT3 2 0.19 0.35 0.48 5.00
23 INT344709 Niacr1 Positive_regulation of Hdl1 1 0.32 2.74 0.46 5.00
24 INT229292 FXR1 Regulation of Gene_expression of FGF19 1 0.08 1.14 0.37 5.00
25 INT229332 BAS Negative_regulation of Pck1 1 0.01 0.2 0.28 5.00
26 INT344704 Positive_regulation of Ppara Positive_regulation of Binding of Hdl1 1 0.13 0.83 0.28 5.00
27 INT344715 Positive_regulation of Ppara Positive_regulation of Gene_expression of Pltp 1 0.02 0.83 0.28 5.00
28 INT333549 Binding of CTLA4 and PDCD1 1 0.36 1.2 0.27 5.00
29 INT344714 Nr1h4 Negative_regulation of Gene_expression of Lipg 1 0.02 0.77 0.23 5.00
30 INT285979 Ros1 Positive_regulation of Trib3 2 0.02 2.18 0.2 5.00
31 INT206089 Negative_regulation of FOSB Negative_regulation of Gene_expression of PTGS2 1 0.00 0.97 0.19 5.00
32 INT300193 Binding of APOA1 and INSL4 1 0.01 2.17 0.18 5.00
33 INT206081 IL6ST Negative_regulation of IL6 1 0.11 0.81 0.17 5.00
34 INT206059 IL6 Positive_regulation of INS 1 0.02 1.16 0.16 5.00
35 INT229289 FGF19 Negative_regulation of CYP7A1 1 0.26 0.32 0.16 5.00
36 INT206070 ANG Positive_regulation of Transcription of IL6 1 0.05 1.5 0.15 5.00
37 INT344721 Binding of AHA and Hdl1 1 0.02 1.16 0.15 5.00
38 INT344707 Scarb1 Positive_regulation of Positive_regulation of Hdl1 1 0.14 0.88 0.14 5.00
39 INT344710 Lipc Positive_regulation of Positive_regulation of Hdl1 1 0.04 0.87 0.14 5.00
40 INT239317 Egfl7 Positive_regulation of Hdl1 2 0.01 2.3 0.14 5.00
41 INT332689 Binding of Edn1 and Ros1 1 0.08 0.71 0.14 5.00
42 INT229290 BAS Negative_regulation of LDLR 1 0.03 0.83 0.13 5.00
43 INT267973 Binding of CHKB and ESR1 1 0.02 1.67 0.13 5.00
44 INT206065 EDN1 Positive_regulation of IL6 1 0.03 0.47 0.12 5.00
45 INT344705 Nr1h2 Regulation of Scarb1 1 0.04 1.53 0.12 5.00
46 INT344706 Nr1h2 Regulation of Abca1 1 0.03 2.39 0.12 5.00
47 INT306921 Ang Positive_regulation of Gene_expression of Ephx2 1 0.15 0.79 0.12 5.00
48 INT332687 Ros1 Positive_regulation of Crk 1 0.17 0.77 0.12 5.00
49 INT344713 Nr1h2 Regulation of Abcg1 1 0.03 2.39 0.12 5.00
50 INT332685 Trib3 Positive_regulation of Binding of Ros1 1 0.01 0.74 0.12 5.00
51 INT229287 BAS Negative_regulation of CRP 1 0.04 0.36 0.11 5.00
52 INT206056 PTK2B Negative_regulation of Positive_regulation of IRF6 1 0.00 0.66 0.1 5.00
53 INT332688 Ros1 Positive_regulation of Binding of Edn1 1 0.10 0.57 0.09 5.00
54 INT206042 Negative_regulation of FDPS Negative_regulation of Binding of FDPS and GGPS1 1 0.00 0 0.09 5.00
55 INT229286 BAS Negative_regulation of FXR1 1 0.02 0.55 0.09 5.00
56 INT199667 Cep290 Regulation of Atf4 1 0.04 1.96 0.09 5.00
57 INT206054 RAC1 Positive_regulation of STAT3 1 0.07 0.11 0.09 5.00
58 INT206075 Negative_regulation of FDPS Negative_regulation of Binding of GGPS1 1 0.01 0 0.09 5.00
59 INT229274 BAS Positive_regulation of BAS Negative_regulation of FXR1 1 0.00 0.55 0.09 5.00
60 INT206078 Binding of FDPS and GGPS1 1 0.00 0 0.09 5.00
61 INT199666 Cntln Regulation of Atf4 1 0.00 1.95 0.09 5.00
62 INT300192 Gene_expression of APOA1 Positive_regulation of HSD11B1 1 0.16 1.08 0.08 5.00
63 INT206072 ANG Positive_regulation of IL6 1 0.05 0.5 0.08 5.00
64 INT229330 Binding of Nr1h2 and Positive_regulation of Gene_expression of GCK 1 0.01 0.62 0.07 5.00
65 INT229333 Binding of Nr1h2 and Positive_regulation of Gene_expression of SLC2A4 1 0.02 0.62 0.07 5.00
66 INT206080 ANG Regulation of Gene_expression of IL6 1 0.03 0.4 0.07 5.00
67 INT206063 ANG Positive_regulation of Gene_expression of KRT20 1 0.00 1.01 0.07 5.00
68 INT229291 BAS Positive_regulation of HSD11B1 1 0.09 0.22 0.06 5.00
69 INT344719 Hdl1 Positive_regulation of Plat 1 0.10 1.23 0.05 5.00
70 INT229288 Binding of FXR1 and BAS 1 0.01 0.59 0.05 5.00
71 INT206087 RAC1 Positive_regulation of Gene_expression of STAT3 1 0.08 0.05 0.05 5.00
72 INT344703 Hdl1 Negative_regulation of Gene_expression of Serpine1 1 0.07 1.26 0.05 5.00
73 INT229329 NR0B2 Negative_regulation of Nr1h2 1 0.03 0.58 0.05 5.00
74 INT229285 BAS Negative_regulation of FGF19 1 0.07 0.33 0.05 5.00
75 INT229275 Binding of FXR1 and BAS Negative_regulation of FXR1 1 0.00 0.59 0.05 5.00
76 INT229331 Binding of FXR1 and Nr1h2 1 0.02 0.61 0.05 5.00
77 INT206083 LDLR Positive_regulation of Binding of STAT3 1 0.02 0.53 0.04 5.00
78 INT332684 Binding of Edn1 and Lep 1 0.09 1.11 0.04 5.00
79 INT206073 Negative_regulation of RAC1 Positive_regulation of IL6 1 0.14 0.06 0.04 5.00
80 INT229293 Positive_regulation of FXR1 Positive_regulation of Gene_expression of NR0B2 1 0.02 0.59 0.04 5.00
81 INT206067 Gene_expression of RAC1 Positive_regulation of Positive_regulation of IL6 1 0.16 0.07 0.04 5.00
82 INT206068 RAC1 Positive_regulation of IL6 1 0.16 0.06 0.04 5.00
83 INT288908 Apoa1 Positive_regulation of Gene_expression of HSD11B1 1 0.03 0.53 0.04 5.00
84 INT206066 LDLR Positive_regulation of Phosphorylation of STAT3 1 0.02 0.52 0.04 5.00
85 INT206071 IRF6 Positive_regulation of Positive_regulation of IL1B 1 0.00 0.58 0.03 5.00
86 INT206076 IL6 Positive_regulation of Positive_regulation of STAT3 1 0.19 0.3 0.03 5.00
87 INT247439 Binding of APOA1 and HSD11B1 3 0.32 5.01 0.03 5.00
88 INT206061 RAC1 Positive_regulation of Positive_regulation of STAT3 1 0.07 0.43 0.03 5.00
89 INT199665 Binding of Fxn and Lamtor3 1 0.00 0.16 0.03 5.00
90 INT300191 Binding of C1S and HSD11B1 1 0.13 1.75 0 5.00
91 INT344708 Hdl1 Positive_regulation of Gene_expression of Plat 1 0.08 1.26 0 5.00
92 INT206085 FDPS Positive_regulation of AGFG1 1 0.00 0.4 0 5.00
93 INT206058 EGFR Negative_regulation of Gene_expression of IL6 1 0.07 0.62 0 5.00
94 INT206079 ANG Regulation of KRT20 1 0.00 0.54 0 5.00
95 INT300195 Binding of C1S and CHDH 1 0.23 2.51 0 5.00
96 INT344720 Niacr1 Negative_regulation of Binding of Hdl1 1 0.17 1.13 0 5.00
97 INT206069 ANG Positive_regulation of Gene_expression of IL6 1 0.05 0.51 0 5.00
98 INT206088 IL6 Positive_regulation of JAK1 1 0.18 0.05 0 5.00
99 INT344722 Binding of Lig3 and Chdh 1 0.00 1.48 0 5.00
100 INT206178 Foxm1 Positive_regulation of Protein_catabolism of Olr1 1 0.00 0.47 0 5.00
101 INT206086 LDLR Positive_regulation of Localization of IL6 1 0.03 0.42 0 5.00
102 INT206060 FDPS Positive_regulation of AKT1 1 0.00 0.4 0 5.00
103 INT206055 F2 Positive_regulation of Gene_expression of IL6 1 0.01 1.24 0 5.00
104 INT306922 Negative_regulation of Ephx2 Positive_regulation of Hdl1 1 0.05 1.06 0 5.00
105 INT206180 Foxm1 Positive_regulation of Transcription of Olr1 1 0.00 0.48 0 5.00
106 INT206077 RAC1 Positive_regulation of Phosphorylation of STAT3 1 0.07 0.35 0 5.00
107 INT344711 Nr1h3 Regulation of Abcg1 1 0.03 1.67 0 5.00
108 INT344717 Binding of Niacr1 and Hdl1 1 0.17 1.51 0 5.00
109 INT349105 Hyal1 Positive_regulation of Gene_expression of Il6 1 0.30 0.25 0 5.00
110 INT300194 HSD11B1 Negative_regulation of CHDH 1 0.08 2.19 0 5.00
111 INT343353 Binding of HSD11B1 and Egfl7 1 0.03 0.97 0 5.00
112 INT344723 Niacr1 Positive_regulation of Binding of APOB 1 0.31 1.05 0 5.00
113 INT267974 APOB Negative_regulation of HSD11B1 1 0.01 0.75 0 5.00
114 INT344712 Nr1h3 Regulation of Abca1 1 0.03 1.68 0 5.00
115 INT344716 Binding of Hdl1 and Chdh 1 0.03 3.24 0 5.00
116 INT206181 FDPS Positive_regulation of ras 1 0.00 0.4 0 5.00
117 INT300197 Binding of APOA1 and C1S 1 0.39 3.56 0 5.00
118 INT300196 Binding of HSD11B1 and CHDH 1 0.07 4.01 0 5.00
119 INT206084 EGF Negative_regulation of Gene_expression of IL6 1 0.05 0.61 0 5.00
120 INT300198 Positive_regulation of Binding of C1S and CHDH 1 0.31 1.63 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hyperlipoproteinemia Type Ii. They are ordered first by their pain relevance and then by number of times they were reported in Hyperlipoproteinemia Type Ii. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT20611 Gene_expression of Asap1 55 0.65 23.71 14.62 100.00
2 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05 99.96
3 INT49759 Negative_regulation of CETP 43 0.58 52 2.68 99.90
4 INT52113 Gene_expression of CETP 25 0.69 25.71 0.99 99.90
5 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21 99.88
6 INT194465 Gene_expression of Ldlr 27 0.76 31.36 2.73 99.80
7 INT252223 Positive_regulation of Gene_expression of Ldlr 3 0.55 10.28 0.37 99.80
8 INT129425 Negative_regulation of Ldlr 22 0.42 17.15 0.97 99.78
9 INT353775 Negative_regulation of Ldlrap1 1 0.02 1 0 99.78
10 INT156818 Gene_expression of Coq10a 8 0.33 3.93 0.76 99.64
11 INT156823 Negative_regulation of Gene_expression of Coq10a 3 0.17 0.49 0 99.64
12 INT28058 Regulation of Apol7b 3 0.02 3.36 0.31 99.42
13 INT224414 Regulation of CIMT 15 0.39 11.75 1.42 99.32
14 INT224415 Gene_expression of CIMT 28 0.57 12.35 1.15 99.28
15 INT127 Positive_regulation of ACOT1 16 0.32 5.12 6.57 99.28
16 INT5166 Binding of Ldlr 14 0.48 11.95 3.32 99.24
17 INT156820 Negative_regulation of Coq10a 2 0.15 1.49 0 99.24
18 INT322935 Positive_regulation of Negative_regulation of CIMT 1 0.18 0.7 0 99.14
19 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 99.12
20 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21 98.92
21 INT105670 Gene_expression of AAVS1 131 0.75 49.24 12.95 98.92
22 INT136831 Gene_expression of Nodal 6 0.22 5.68 0.97 98.92
23 INT105669 Positive_regulation of Gene_expression of AAVS1 20 0.49 9.02 2.06 98.92
24 INT26546 Positive_regulation of Gene_expression of Hras1 35 0.70 16.59 4.54 98.92
25 INT322934 Negative_regulation of Gene_expression of CIMT 1 0.15 0.7 0 98.90
26 INT70647 Regulation of CETP 7 0.61 4.53 0.21 98.80
27 INT61423 Gene_expression of Egfl7 23 0.14 24.96 0.66 98.72
28 INT61420 Positive_regulation of Gene_expression of Egfl7 20 0.12 18.96 0.13 98.72
29 INT22454 Regulation of Crp 213 0.62 160.67 49.24 98.68
30 INT241211 Negative_regulation of CIMT 8 0.37 2.67 0 98.66
31 INT267959 Negative_regulation of Positive_regulation of APOA1 2 0.41 1.4 0 98.32
32 INT21712 Positive_regulation of APOA1 32 0.67 21.64 2.64 98.32
33 INT51739 Negative_regulation of Apob 9 0.42 4.21 0.78 98.28
34 INT286443 Positive_regulation of PCSK9 1 0.16 0.48 0 98.26
35 INT9649 Positive_regulation of LPA 105 0.69 74.75 13.89 98.16
36 INT67101 Gene_expression of DST 47 0.54 25.92 9.59 98.12
37 INT168304 Positive_regulation of SNRPB 17 0.25 9.62 1.64 98.00
38 INT224413 Positive_regulation of CIMT 25 0.68 23.61 3.14 97.94
39 INT20612 Positive_regulation of Asap1 36 0.68 24.35 6.06 97.94
40 INT142800 Positive_regulation of Ldlr 21 0.68 14.75 0.6 97.88
41 INT63341 Negative_regulation of ICAM1 42 0.59 30.45 9.5 97.88
42 INT1626 Binding of Cog1 8 0.21 7.86 0.34 97.88
43 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32 97.68
44 INT306916 Binding of Ephx2 7 0.37 5.88 0.29 97.40
45 INT92455 Transcription of SNRPB 3 0.52 1.21 1.27 97.40
46 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 97.20
47 INT297928 Positive_regulation of Positive_regulation of CIMT 2 0.15 2.24 0 97.04
48 INT306909 Transcription of Ephx2 1 0.53 2.04 0 96.84
49 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 96.76
50 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 96.64
51 INT57728 Regulation of LDLR 25 0.41 13.18 3.46 96.60
52 INT252222 Regulation of Ldlr 5 0.34 4.3 0.19 96.46
53 INT10828 Regulation of Apob 7 0.39 7.55 0.83 96.46
54 INT293307 Regulation of Gene_expression of Ldlr 3 0.19 2.77 0.07 96.46
55 INT325018 Regulation of Gene_expression of Apob 2 0.16 1.59 0.03 96.46
56 INT353787 Regulation of Gene_expression of Pcsk9 1 0.24 0.36 0 96.46
57 INT10827 Gene_expression of Apob 16 0.78 13.08 0.9 96.28
58 INT353778 Gene_expression of Pcsk9 1 0.42 0.36 0 95.80
59 INT94438 Gene_expression of OLR1 86 0.78 80.38 11.03 95.64
60 INT41986 Positive_regulation of Gene_expression of HSD11B1 26 0.49 32.84 1.52 95.64
61 INT300233 Positive_regulation of Gene_expression of LCAT 1 0.29 0.98 0 95.64
62 INT39406 Positive_regulation of OLR1 45 0.70 37.8 7.72 95.36
63 INT164632 Positive_regulation of EGFL7 8 0.32 3.03 0.71 95.36
64 INT198900 Positive_regulation of Vldlr 3 0.26 1.44 0.12 95.12
65 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 94.84
66 INT94437 Positive_regulation of Gene_expression of OLR1 17 0.70 16.04 2.8 94.80
67 INT17813 Positive_regulation of Hdl2 11 0.36 12.23 1.04 94.68
68 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04 94.64
69 INT5164 Negative_regulation of Ldlr 83 0.58 55.01 7.87 94.48
70 INT187415 Gene_expression of LCAT 3 0.39 1.26 0 93.72
71 INT17913 Regulation of HSD11B1 87 0.60 93.23 6.04 93.68
72 INT205274 Gene_expression of Cs 2 0.75 2.08 0.36 93.28
73 INT344633 Negative_regulation of Cs 1 0.42 0.82 0 93.28
74 INT189970 Positive_regulation of Positive_regulation of SNRPB 1 0.22 1.69 0.08 92.64
75 INT115192 Phosphorylation of IL6 7 0.70 1.55 0.84 92.52
76 INT353784 Protein_catabolism of Ldlr 1 0.52 1.85 0 92.36
77 INT53261 Gene_expression of exf 5 0.07 4.93 1.24 91.56
78 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 91.52
79 INT17686 Negative_regulation of Hdl1 72 0.36 81.85 7.74 91.52
80 INT19177 Negative_regulation of GRHPR 19 0.53 12.65 2.71 91.04
81 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 90.96
82 INT197016 Positive_regulation of Gene_expression of LDLR 13 0.50 5.82 0.24 90.96
83 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 90.72
84 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 90.72
85 INT300232 Gene_expression of PCSK9 1 0.57 0.8 0 90.56
86 INT9466 Binding of APOB 27 0.41 19.36 1.56 90.52
87 INT142802 Binding of Ldlr 8 0.47 5.08 0.65 89.96
88 INT46843 Binding of Trf 10 0.47 3.45 0.35 89.96
89 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 89.44
90 INT17086 Binding of HSD11B1 84 0.47 122.28 6.16 89.32
91 INT9467 Negative_regulation of APOB 14 0.57 10.49 0.88 89.04
92 INT22836 Regulation of F2 9 0.59 2.3 1.49 89.04
93 INT27639 Negative_regulation of Gene_expression of C9orf3 4 0.57 3.97 0.48 88.92
94 INT9650 Gene_expression of LPA 141 0.75 104.57 29 88.52
95 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 88.46
96 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 88.46
97 INT176092 Negative_regulation of Gene_expression of Hras1 5 0.03 3.31 0 88.32
98 INT232235 Negative_regulation of Gene_expression of Ldlr 3 0.42 3.13 0.34 88.32
99 INT37799 Gene_expression of Apob 13 0.56 10.59 1.36 88.20
100 INT339386 Negative_regulation of Gene_expression of Apob 3 0.43 1.91 0.34 88.20
101 INT17685 Negative_regulation of Cog1 23 0.42 15.65 3.56 87.76
102 INT9054 Negative_regulation of Positive_regulation of Cog1 3 0.08 1.38 0.28 87.76
103 INT19967 Gene_expression of C9orf3 18 0.75 26.51 4.6 87.72
104 INT198884 Gene_expression of Vldlr 13 0.70 2.41 0.44 87.68
105 INT36453 Binding of ABCA1 48 0.45 19.9 10.84 87.68
106 INT27634 Gene_expression of Hrtrt1 2 0.00 0.93 0.59 87.28
107 INT227457 Positive_regulation of Gene_expression of CIMT 9 0.15 3.19 0.54 87.08
108 INT9055 Positive_regulation of Cog1 22 0.68 14.08 2.95 87.08
109 INT80550 Positive_regulation of Gene_expression of Asap1 8 0.42 5.8 3.09 85.92
110 INT27635 Regulation of Hrtrt1 4 0.03 4.02 0.38 85.80
111 INT353783 Positive_regulation of Gene_expression of Vldlr 1 0.28 0.51 0 85.72
112 INT102076 Regulation of DST 15 0.22 10 3.5 85.72
113 INT180033 Regulation of CFM1 2 0.21 1.09 0.1 85.72
114 INT11957 Negative_regulation of LPA 52 0.59 39.09 6.84 85.60
115 INT344640 Regulation of Gene_expression of CIMT 1 0.14 0.24 0 85.56
116 INT349103 Binding of Hyal1 1 0.29 1.07 0.09 85.44
117 INT89584 Regulation of Gene_expression of Asap1 2 0.18 0.31 0.33 85.36
118 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 84.72
119 INT349104 Positive_regulation of Hyal1 1 0.54 1.27 0.05 84.24
120 INT229279 Negative_regulation of Cby1 15 0.42 9.4 0.31 83.56
121 INT180032 Positive_regulation of CFM1 1 0.02 1.07 0.1 83.04
122 INT34829 Positive_regulation of Gnat3 27 0.46 5.24 4.14 82.92
123 INT238793 Gene_expression of Cbl 6 0.03 3.01 0.43 82.56
124 INT229278 Positive_regulation of Cby1 5 0.67 8.07 0.85 82.28
125 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31 82.00
126 INT5048 Binding of Edn1 55 0.47 18.86 19.16 81.76
127 INT31582 Gene_expression of Hdl1 103 0.66 118.95 6.42 81.72
128 INT212966 Negative_regulation of Gene_expression of Hdl1 8 0.27 10.98 0.49 81.72
129 INT17565 Regulation of Gpt 85 0.60 43.64 13.68 79.08
130 INT80656 Regulation of SLC17A5 15 0.26 6.89 3.19 79.08
131 INT15773 Negative_regulation of C9orf3 8 0.57 6.26 1.06 76.08
132 INT300226 Regulation of DGAT1 1 0.01 1.67 0.06 75.88
133 INT9548 Gene_expression of CHKB 99 0.65 50.86 9.03 75.72
134 INT15400 Positive_regulation of Hrtrt1 5 0.22 1.02 1.74 75.40
135 INT22723 Negative_regulation of Hrtrt1 6 0.21 1.52 3.73 75.20
136 INT65489 Regulation of Gene_expression of Crp 28 0.59 29.17 7.56 75.00
137 INT308409 Regulation of Gene_expression of OLR1 1 0.35 0.72 0 74.88
138 INT39458 Negative_regulation of SOAT1 8 0.57 10.56 1.83 73.44
139 INT64247 Regulation of Phdlc1 2 0.03 2.21 0.66 73.32
140 INT180031 Gene_expression of IBGC1 1 0.05 1.38 0.2 72.96
141 INT203827 Localization of Apob 3 0.32 1.81 0.13 72.20
142 INT187410 Localization of Cd320 14 0.78 9.03 0.31 71.44
143 INT34585 Negative_regulation of Positive_regulation of HSD11B1 31 0.57 43.54 2.47 71.04
144 INT187405 Gene_expression of Cand1 8 0.65 7.25 0.16 70.96
145 INT173656 Negative_regulation of Cebpg 4 0.57 1.23 0.24 70.32
146 INT38673 Negative_regulation of KRT20 38 0.42 22.49 2.77 69.64
147 INT189923 Binding of Pol 5 0.20 2.09 0.04 69.16
148 INT7475 Positive_regulation of Hdl1 138 0.67 175.81 15.05 69.00
149 INT192841 Binding of Mela 9 0.43 4.29 0.58 68.80
150 INT288898 Negative_regulation of Cand1 1 0.42 0.39 0 68.16
151 INT213081 Negative_regulation of Egfl7 7 0.04 5.14 0.15 67.56
152 INT48129 Negative_regulation of Slc2a4 7 0.59 3.19 1.21 66.88
153 INT179360 Positive_regulation of HDLBP 5 0.11 5.09 0.39 65.92
154 INT192541 Gene_expression of Tg(Foxn1)E1Hon 20 0.20 8.98 2.4 64.64
155 INT172177 Protein_catabolism of INCENP 18 0.37 6.34 2.91 63.28
156 INT43985 Regulation of LPA 29 0.62 20.79 3.29 62.88
157 INT353774 Protein_catabolism of Lvs 1 0.12 0.92 0.04 60.76
158 INT306911 Positive_regulation of Ephx2 4 0.69 5.39 0.63 59.20
159 INT22024 Negative_regulation of HBG1 45 0.58 26 6.8 57.48
160 INT10861 Negative_regulation of Vldlr 5 0.11 3.22 0.27 56.76
161 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 56.64
162 INT50080 Binding of APOE 38 0.45 29.61 2.67 55.72
163 INT240615 Binding of Apob 2 0.07 0.85 0.04 55.72
164 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 55.20
165 INT20462 Binding of ESR1 210 0.44 102.7 26.34 54.12
166 INT135306 Binding of CYP2C8 10 0.46 4.37 0.46 53.72
167 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 52.56
168 INT37390 Regulation of Crp 39 0.46 28.74 11.45 50.36
169 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 50.00
170 INT32203 Negative_regulation of Crp 48 0.58 32.77 11.89 50.00
171 INT17890 Negative_regulation of HMGCR 26 0.42 12.05 1.94 50.00
172 INT105021 Binding of GOPC 187 0.40 60.39 20.38 49.84
173 INT332683 Positive_regulation of Gene_expression of Ddah1 1 0.12 1.75 0.05 49.00
174 INT332682 Gene_expression of Ddah1 1 0.13 1.75 0.05 49.00
175 INT349101 Protein_catabolism of Hyal1 1 0.51 0.29 0 47.44
176 INT286085 Binding of Cand1 3 0.36 1.25 0 46.76
177 INT187994 Binding of CIMT 20 0.47 12.97 2.04 46.52
178 INT36142 Negative_regulation of Hmgcr 33 0.46 15.91 3.54 43.68
179 INT169697 Negative_regulation of Ephx2 35 0.59 38.21 5.92 43.28
180 INT199650 Negative_regulation of Phyh 1 0.42 2.2 0.04 40.60
181 INT11761 Negative_regulation of DST 13 0.42 7.66 3.65 38.52
182 INT28788 Regulation of LYZ 5 0.42 1.8 1.24 38.08
183 INT285743 Regulation of CD68 2 0.33 1.82 0.2 37.04
184 INT8667 Localization of HSD11B1 22 0.73 22.74 1.25 34.20
185 INT53184 Negative_regulation of CYP27A1 46 0.57 16.04 5.28 32.80
186 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 30.48
187 INT39407 Binding of OLR1 18 0.48 14.79 2.51 30.08
188 INT39404 Positive_regulation of Binding of OLR1 3 0.50 1.24 0.27 30.08
189 INT290205 Negative_regulation of Protein_catabolism of AAVS1 2 0.20 0.7 0 29.32
190 INT290207 Protein_catabolism of AAVS1 2 0.35 0.69 0 28.56
191 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 27.44
192 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 26.56
193 INT94454 Gene_expression of CD68 73 0.72 63.94 10.43 26.00
194 INT288901 Negative_regulation of PECR 1 0.01 0.42 0 26.00
195 INT149332 Gene_expression of CD163 19 0.75 13.63 3.65 25.76
196 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 24.96
197 INT55880 Negative_regulation of Gene_expression of CCL2 49 0.59 22.37 18.09 24.96
198 INT290336 Negative_regulation of Scarb1 4 0.31 1.77 0.17 24.76
199 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 24.64
200 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 24.64
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