D:Hypersensitivity Pneumonitis

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Disease Term
Synonyms Allergic Alveolitides Extrinsic, Allergic Alveolitis, Allergic Alveolitis Extrinsic, Allergic Extrinsic Alveolitis Disorder, Allergic Interstitial Pneumonitis, ALLERGIC PNEUMONITIS, ALVEOLITIDES EXTRINSIC ALLERGIC, ALVEOLITIS EXTRINSIC ALLERGIC, Bagassosis, Baggasosis, Eaa Extrinsic Allergic Alveolitis
Documents 81
Hot Single Events 78
Hot Interactions 8

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hypersensitivity Pneumonitis. They are ordered first by their relevance to Hypersensitivity Pneumonitis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT300655 Il4 Positive_regulation of Gene_expression of IFN1@ 1 0.22 0.82 0.08 100.00
2 INT194806 MAPK1 Positive_regulation of CD28 Positive_regulation of Il4 1 0.08 0.42 0.13 95.08
3 INT194817 CD28 Positive_regulation of Il4 1 0.15 0.41 0.13 95.08
4 INT194717 CD28 Positive_regulation of IL13 1 0.03 0.41 0.13 95.08
5 INT230438 Binding of PDX1 and HAUS7 1 0.02 2.29 0.35 94.56
6 INT179186 Fcer2a Regulation of Positive_regulation of Ahr 1 0.05 1.23 0.23 88.64
7 INT194818 Positive_regulation of IL9 Positive_regulation of Positive_regulation of Trav6-3 1 0.00 0.23 0.14 84.24
8 INT270995 Binding of CYSLTR2 and OR6B1 1 0.01 2.14 0.15 83.92
9 INT300652 Ephb6 Regulation of Gene_expression of Cxcl10 1 0.01 0.59 0.41 76.96
10 INT230437 Binding of PDX1 and HRCT1 1 0.04 2.45 0.43 76.60
11 INT194666 Binding of CXCL2 and HNRNPA0 1 0.04 0.44 0.32 74.96
12 INT194733 Binding of CPOX and HNRNPA0 1 0.01 0.44 0.32 73.52
13 INT194706 Binding of TNF and HNRNPA0 1 0.06 0.43 0.32 73.12
14 INT88698 Binding of Max and Cpm 1 0.00 0.27 0.18 61.04
15 INT88702 Binding of CPM and Max 1 0.01 0.27 0.18 61.04
16 INT194696 TTPA Positive_regulation of Phosphorylation of MAPKAPK2 1 0.01 0.08 0.17 39.92
17 INT194737 Binding of TTPA and MAPKAPK2 1 0.01 0.08 0.17 39.92
18 INT194722 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of CRP 1 0.09 1.49 0.41 26.52
19 INT194705 Negative_regulation of MAPK1 Negative_regulation of Positive_regulation of IK 1 0.00 1.46 0.41 26.52
20 INT271000 Binding of HLA-DPB1 and Aia1 1 0.01 1.7 0.18 20.24
21 INT185379 Binding of IRF6 and TLR2 4 0.08 2.88 0.35 15.32
22 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00
23 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85 5.00
24 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83 5.00
25 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07 5.00
26 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 5.00
27 INT194685 MAPK1 Regulation of Gene_expression of IL10 1 0.06 1.18 0.7 5.00
28 INT194676 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of IL10 1 0.05 0.34 0.5 5.00
29 INT193219 Binding of LTC4S and CYSLTR2 2 0.28 2.2 0.44 5.00
30 INT194713 MAPK1 Regulation of Gene_expression of TNF 1 0.10 1.66 0.38 5.00
31 INT353454 Binding of BRCA1 and IL17A 1 0.00 2.55 0.36 5.00
32 INT353452 Binding of AGRP and BRCA1 1 0.00 3.89 0.34 5.00
33 INT194710 MAPK1 Regulation of Gene_expression of IK 1 0.00 0.24 0.31 5.00
34 INT333398 CFD Negative_regulation of Gene_expression of Pdgfa 1 0.02 0.64 0.3 5.00
35 INT194821 MAPK1 Regulation of Hand2 1 0.03 1.27 0.28 5.00
36 INT171050 Negative_regulation of F13A1 Regulation of PLG 1 0.02 0.55 0.28 5.00
37 INT171048 F13A1 Regulation of PLG 1 0.02 0.55 0.27 5.00
38 INT194682 Negative_regulation of MAPK1 Positive_regulation of Gene_expression of IL10 1 0.05 0.17 0.27 5.00
39 INT353448 BRCA1 Positive_regulation of CCL2 1 0.01 1.37 0.26 5.00
40 INT353449 BRCA1 Positive_regulation of IL4 1 0.00 1.37 0.26 5.00
41 INT353455 BRCA1 Positive_regulation of IL13 1 0.00 1.37 0.26 5.00
42 INT194810 Il4 Regulation of Positive_regulation of Nfatc1 1 0.02 0.15 0.25 5.00
43 INT194670 CREB1 Regulation of Gene_expression of CD4 1 0.05 0.07 0.25 5.00
44 INT194714 CREB1 Regulation of Gene_expression of IK 1 0.00 0.07 0.25 5.00
45 INT194693 FOSL2 Positive_regulation of Gene_expression of IK 1 0.00 0.08 0.24 5.00
46 INT194669 FOSB Positive_regulation of Gene_expression of IK 1 0.00 0.08 0.24 5.00
47 INT194820 Junb Positive_regulation of Gene_expression of IK 1 0.00 0.08 0.24 5.00
48 INT194832 Junb Positive_regulation of Gene_expression of FOSB 1 0.18 0.09 0.24 5.00
49 INT171049 Binding of FAS and Positive_regulation of Gene_expression of CASP3 1 0.04 1.41 0.24 5.00
50 INT194686 FOSL2 Positive_regulation of Gene_expression of FOSB 1 0.11 0.09 0.24 5.00
51 INT194662 MAPK1 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of IL10 1 0.02 0.17 0.23 5.00
52 INT271001 Binding of PTGER2 and Aia1 1 0.00 1.28 0.23 5.00
53 INT194702 MAPK1 Negative_regulation of Gene_expression of IL10 1 0.05 0.16 0.23 5.00
54 INT333394 CFD Negative_regulation of Gene_expression of Cat 1 0.03 0.79 0.22 5.00
55 INT115143 MAPK1 Positive_regulation of TFAM 2 0.02 0.49 0.22 5.00
56 INT194725 MAPK1 Regulation of Transcription of IK 1 0.00 0.06 0.22 5.00
57 INT333397 CFD Negative_regulation of Gene_expression of Nos2 1 0.04 0.8 0.22 5.00
58 INT194809 MAPK1 Positive_regulation of Binding of Crebbp and Nfatc1 1 0.00 0.08 0.19 5.00
59 INT194807 MAPK1 Positive_regulation of Binding of CREB1 and Nfatc1 1 0.01 0.08 0.19 5.00
60 INT194805 MAPK1 Positive_regulation of Binding of CREB1 and Crebbp 1 0.02 0.08 0.19 5.00
61 INT194830 MAPK1 Positive_regulation of Gene_expression of Nfatc1 1 0.02 0.08 0.19 5.00
62 INT333393 CFD Positive_regulation of Gene_expression of Timp1 1 0.07 0.82 0.16 5.00
63 INT194700 CD28 Positive_regulation of MAPK1 1 0.10 0.55 0.16 5.00
64 INT194708 TNFRSF8 Positive_regulation of MAPK1 1 0.06 0.55 0.16 5.00
65 INT194667 EPHB6 Positive_regulation of MAPK1 1 0.12 0.54 0.16 5.00
66 INT194811 Binding of Crebbp and Nfatc1 1 0.00 0.07 0.16 5.00
67 INT194838 Binding of CREB1 and Nfatc1 1 0.01 0.07 0.16 5.00
68 INT267138 Binding of CDH5 and PECAM1 2 0.16 2.69 0.16 5.00
69 INT194826 Binding of CREB1 and Crebbp 1 0.02 0.07 0.16 5.00
70 INT194829 Gata3 Positive_regulation of IL13 1 0.01 0.12 0.15 5.00
71 INT194816 MAPK1 Negative_regulation of Phosphorylation of Nfatc1 1 0.01 0.07 0.15 5.00
72 INT194835 Gata3 Positive_regulation of IL5 1 0.01 0.12 0.15 5.00
73 INT194836 MAPK1 Negative_regulation of Nfatc1 1 0.01 0.07 0.15 5.00
74 INT194833 Binding of IL5 and Gata3 1 0.01 0.12 0.15 5.00
75 INT194827 Binding of IL13 and Gata3 1 0.01 0.12 0.15 5.00
76 INT331628 Binding of HLA-DQA2 and Pain1 1 0.01 2.13 0.14 5.00
77 INT194697 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of IL5 1 0.03 0.1 0.14 5.00
78 INT353451 Binding of BRCA1 and CRP 1 0.01 1.18 0.14 5.00
79 INT331627 Binding of HLA-DRB3 and Pain1 1 0.00 2.15 0.14 5.00
80 INT271003 Binding of TBXA2R and Aia1 1 0.01 1.81 0.14 5.00
81 INT353453 Binding of BRCA1 and IL4 1 0.00 1.18 0.14 5.00
82 INT333396 CFD Positive_regulation of Bcl2l1 1 0.05 0.98 0.13 5.00
83 INT270996 TBXA2R Regulation of LTC4S 1 0.24 0.83 0.13 5.00
84 INT271002 Binding of LTC4S and Aia1 1 0.00 0.98 0.12 5.00
85 INT331612 ETV4 Positive_regulation of Gene_expression of TGFB1 1 0.00 1.32 0.12 5.00
86 INT194814 Cd3e Positive_regulation of Gene_expression of Il4 1 0.05 0 0.12 5.00
87 INT194671 MAPKAPK2 Positive_regulation of CREB1 1 0.06 0.05 0.1 5.00
88 INT194689 MAPKAPK2 Positive_regulation of TFAM 1 0.00 0.05 0.1 5.00
89 INT194822 Negative_regulation of MAPK1 Negative_regulation of Binding of Sp1 1 0.04 0.05 0.1 5.00
90 INT194825 Camk4 Positive_regulation of CREB1 1 0.01 0 0.1 5.00
91 INT194721 MAPK1 Positive_regulation of CREB1 1 0.08 0.05 0.1 5.00
92 INT194837 Camk4 Positive_regulation of TFAM 1 0.00 0 0.1 5.00
93 INT194819 Positive_regulation of Trav6-3 Positive_regulation of MAPK1 1 0.02 0.39 0.1 5.00
94 INT194730 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of IL2 1 0.06 0 0.09 5.00
95 INT194742 SOAT1 Positive_regulation of Positive_regulation of IK 1 0.00 0.1 0.09 5.00
96 INT194718 DPP4 Positive_regulation of MAPK1 1 0.02 0.29 0.09 5.00
97 INT194828 IL12A Positive_regulation of Phosphorylation of Stat4 1 0.03 0.08 0.09 5.00
98 INT194674 CD28 Negative_regulation of Gene_expression of IL13 1 0.02 0.06 0.08 5.00
99 INT194728 Binding of EPHB6 and Positive_regulation of MAPK1 1 0.12 0.26 0.08 5.00
100 INT194739 MAPK1 Negative_regulation of Gene_expression of IL13 1 0.03 0.05 0.08 5.00
101 INT194663 MAPK1 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of IL13 1 0.02 0.05 0.08 5.00
102 INT194668 CREB1 Negative_regulation of Transcription of IK 1 0.00 0.07 0.08 5.00
103 INT194740 EPHA1 Positive_regulation of MAPK1 1 0.01 0.28 0.08 5.00
104 INT331626 Edn1 Positive_regulation of Itk 1 0.00 0.57 0.07 5.00
105 INT194723 GADD45A Regulation of Regulation of MAPK1 1 0.06 0 0.07 5.00
106 INT331629 Binding of TGFB1 and Positive_regulation of Gene_expression of Itk 1 0.00 0.84 0.07 5.00
107 INT194824 Il4 Positive_regulation of MAPK1 1 0.26 0 0.07 5.00
108 INT267137 ICAM1 Regulation of ITGAL 2 0.12 0.57 0.07 5.00
109 INT194683 Negative_regulation of MAPK1 Negative_regulation of IFNA1 1 0.02 0.07 0.07 5.00
110 INT194834 Il4 Positive_regulation of Positive_regulation of MAPK1 1 0.18 0 0.06 5.00
111 INT194678 IL2 Positive_regulation of Positive_regulation of MAPK1 1 0.05 0 0.06 5.00
112 INT194724 TNFRSF8 Positive_regulation of Gene_expression of IL13 1 0.02 0 0.06 5.00
113 INT194831 CD28 Positive_regulation of Gene_expression of Il4 1 0.15 0 0.06 5.00
114 INT194664 Negative_regulation of MAPK1 Negative_regulation of IL2 1 0.06 0 0.05 5.00
115 INT353450 Binding of BRCA1 and VEGFA 1 0.01 0.82 0.05 5.00
116 INT194665 IL12A Positive_regulation of MAPK1 1 0.06 0 0.05 5.00
117 INT194672 GADD45A Positive_regulation of Positive_regulation of MAPK1 1 0.14 0.06 0.05 5.00
118 INT194688 PAK1 Positive_regulation of GADD45A 1 0.11 0 0.05 5.00
119 INT310727 Binding of DKC1 and TERT 1 0.23 0.91 0.05 5.00
120 INT194727 MAP3K4 Positive_regulation of MAP2K6 1 0.06 0 0.04 5.00
121 INT194699 MAP2K1 Positive_regulation of MAPK8 1 0.05 0 0.04 5.00
122 INT194703 MAP2K1 Positive_regulation of MAP2K6 1 0.21 0 0.04 5.00
123 INT194735 IL18 Positive_regulation of Positive_regulation of MAPK1 1 0.05 0 0.04 5.00
124 INT194694 MAPK1 Negative_regulation of Gene_expression of IL2 1 0.04 0 0.04 5.00
125 INT194677 Binding of GADD45A and MAP2K1 1 0.27 0 0.04 5.00
126 INT194719 MAP2K1 Positive_regulation of MAPK1 1 0.27 0 0.04 5.00
127 INT194673 MAP3K4 Positive_regulation of MAP2K4 1 0.06 0 0.04 5.00
128 INT194731 MAP3K4 Positive_regulation of MAPK8 1 0.02 0 0.04 5.00
129 INT194726 Binding of GADD45A and MAP3K4 1 0.06 0 0.04 5.00
130 INT213207 Negative_regulation of ASAP2 Negative_regulation of PVR 1 0.01 0.45 0.04 5.00
131 INT194681 MAP3K4 Positive_regulation of MAP2K3 1 0.07 0 0.04 5.00
132 INT194701 MAP2K1 Positive_regulation of MAP2K4 1 0.21 0 0.04 5.00
133 INT194732 MAP2K1 Positive_regulation of Gene_expression of MAPK1 1 0.27 0 0.04 5.00
134 INT194680 MAP3K4 Positive_regulation of MAPK1 1 0.08 0 0.04 5.00
135 INT194741 IL18 Positive_regulation of Gene_expression of GADD45A 1 0.05 0 0.04 5.00
136 INT194729 MAP3K4 Positive_regulation of Gene_expression of MAPK1 1 0.08 0 0.04 5.00
137 INT194679 IL12A Positive_regulation of GADD45A 1 0.04 0 0.04 5.00
138 INT194704 IL18 Positive_regulation of GADD45A 1 0.08 0 0.04 5.00
139 INT194736 Positive_regulation of MAPK1 Positive_regulation of Gene_expression of GADD45A 1 0.13 0 0.04 5.00
140 INT194691 MAP2K1 Positive_regulation of MAP2K3 1 0.23 0 0.04 5.00
141 INT213206 ASAP2 Negative_regulation of PVR 1 0.01 0.44 0.04 5.00
142 INT194823 Binding of Trav6-3 and Positive_regulation of Phosphorylation of MAPK1 1 0.02 0.1 0.03 5.00
143 INT194707 RAC1 Positive_regulation of PAK1 1 0.01 0 0.03 5.00
144 INT194738 Binding of PAK1 and RAC1 1 0.01 0 0.03 5.00
145 INT194690 MAPK1 Regulation of IFNA1 1 0.02 0 0 5.00
146 INT194716 Positive_regulation of Binding of VAV1 and ZAP70 1 0.04 0 0 5.00
147 INT194743 GADD45A Positive_regulation of Negative_regulation of MAPK1 1 0.13 0.06 0 5.00
148 INT194698 Binding of ZAP70 and LAT 1 0.04 0 0 5.00
149 INT331611 NKX2-1 Regulation of Transcription of SFTPB 1 0.01 0.49 0 5.00
150 INT333395 Binding of CFD and Aes 1 0.03 0.24 0 5.00
151 INT194711 LAT Positive_regulation of Binding of VAV1 1 0.03 0 0 5.00
152 INT267136 Binding of CD44 and FN1 2 0.04 0.56 0 5.00
153 INT194692 Binding of VAV1 and LAT 1 0.02 0 0 5.00
154 INT194687 Binding of VAV1 and ZAP70 1 0.03 0 0 5.00
155 INT194695 RAC1 Positive_regulation of PAK4 1 0.00 0 0 5.00
156 INT194675 MAPK14 Positive_regulation of CREB1 1 0.07 0.33 0 5.00
157 INT194684 MAPK14 Positive_regulation of Transcription of CREB1 1 0.07 0.33 0 5.00
158 INT194734 ZAP70 Positive_regulation of Binding of VAV1 1 0.05 0 0 5.00
159 INT274437 Binding of IRF6 and LIPA 1 0.00 0.09 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hypersensitivity Pneumonitis. They are ordered first by their pain relevance and then by number of times they were reported in Hypersensitivity Pneumonitis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT192409 Positive_regulation of Gene_expression of IFN1@ 102 0.67 64.66 18.8 100.00
2 INT197373 Positive_regulation of Tmie 7 0.33 2.89 0.47 99.96
3 INT300647 Positive_regulation of Positive_regulation of Tmie 1 0.25 0.65 0.09 99.96
4 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 99.92
5 INT197372 Gene_expression of Tmie 16 0.51 9.08 1.9 99.84
6 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 99.76
7 INT131359 Positive_regulation of Gene_expression of Cd4 40 0.58 22.43 7.53 99.76
8 INT5788 Gene_expression of IL2RA 60 0.75 40.67 9.98 99.74
9 INT327486 Binding of Dpa 1 0.02 1.74 0 99.72
10 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 99.58
11 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 99.48
12 INT11807 Gene_expression of Il2 266 0.78 112 64.97 99.34
13 INT20371 Gene_expression of Cd8a 125 0.60 67.59 8.97 99.12
14 INT302520 Negative_regulation of Gene_expression of Slc28a1 2 0.12 1.85 0.19 99.08
15 INT212624 Gene_expression of Slc28a1 9 0.53 3.47 0.44 98.72
16 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 98.56
17 INT213215 Gene_expression of SS18L1 2 0.58 3.71 0.29 98.52
18 INT94465 Positive_regulation of Gene_expression of Hand1 43 0.38 29.76 10.88 98.36
19 INT230442 Binding of HAUS7 1 0.02 2.2 0.3 98.20
20 INT171060 Gene_expression of PDX1 72 0.75 72.57 17.97 97.84
21 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 97.72
22 INT170333 Binding of IFN1@ 68 0.47 49.01 9.72 97.56
23 INT88700 Gene_expression of CPM 8 0.76 2.55 0.56 96.44
24 INT170754 Localization of IFN1@ 121 0.78 66.78 15.6 96.40
25 INT209033 Positive_regulation of Localization of IFN1@ 27 0.67 12.55 2.84 96.40
26 INT230086 Negative_regulation of Localization of IFN1@ 9 0.57 6.06 1.25 96.40
27 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 96.24
28 INT19215 Gene_expression of Cpm 13 0.65 1.63 1.45 96.20
29 INT187819 Regulation of IFN1@ 25 0.60 12.89 3.55 96.16
30 INT181133 Negative_regulation of Gene_expression of Cd8a 7 0.37 2.65 0.25 96.00
31 INT135527 Negative_regulation of Gene_expression of Cd4 17 0.43 6.72 1.09 95.84
32 INT296902 Regulation of Gene_expression of Tmie 2 0.23 1.23 0.12 95.84
33 INT300646 Negative_regulation of Gene_expression of Tmie 2 0.24 0.64 0.17 95.44
34 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 95.08
35 INT73499 Positive_regulation of IL13 23 0.39 20.03 6.53 95.08
36 INT97434 Positive_regulation of Positive_regulation of Il4 8 0.40 3.51 1.66 95.08
37 INT194784 Positive_regulation of Positive_regulation of IL13 1 0.06 0.41 0.13 95.08
38 INT177759 Negative_regulation of IFN1@ 51 0.57 31.81 7.76 94.08
39 INT178183 Binding of Cd8a 16 0.32 7.8 0.85 93.68
40 INT53196 Binding of Cd4 44 0.47 27.28 5.85 93.68
41 INT300649 Regulation of Gene_expression of Ephb6 1 0.04 0.56 0.12 93.40
42 INT157430 Gene_expression of Ephb6 18 0.70 8.13 7.14 93.20
43 INT149138 Binding of PDX1 27 0.37 32.62 9.33 93.20
44 INT88699 Regulation of Gene_expression of CPM 1 0.27 0.34 0.15 92.64
45 INT147572 Gene_expression of Ahr 73 0.75 38.99 3.15 91.96
46 INT221269 Binding of BRCA1 14 0.40 31.77 2.7 91.60
47 INT133214 Regulation of PDX1 9 0.34 10.26 3.36 91.60
48 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 91.24
49 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28 91.12
50 INT74703 Positive_regulation of Gene_expression of Cpm 1 0.42 0.34 0.15 90.96
51 INT74702 Regulation of Gene_expression of Cpm 1 0.23 0.34 0.15 90.96
52 INT213221 Negative_regulation of ASAP2 1 0.01 5.83 0.46 90.88
53 INT119063 Gene_expression of BRCA1 24 0.67 30.04 4.17 90.44
54 INT94082 Regulation of Gene_expression of IK 19 0.23 10.03 7.93 90.40
55 INT56448 Regulation of ICAM1 52 0.60 55.1 10.96 89.88
56 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 89.68
57 INT72060 Positive_regulation of Gene_expression of Ros1 127 0.41 76.76 20.91 89.36
58 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 88.96
59 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73 87.88
60 INT60442 Negative_regulation of Fev 2 0.37 3.82 0.82 84.96
61 INT116902 Positive_regulation of CD28 17 0.47 13.56 4.27 84.96
62 INT147607 Binding of TERT 16 0.48 12.36 1.31 84.60
63 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44 84.32
64 INT36892 Positive_regulation of Trav6-3 57 0.68 12.15 3.8 84.24
65 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85 84.04
66 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 83.28
67 INT10016 Negative_regulation of CD8A 81 0.42 56.68 13.15 82.64
68 INT19185 Negative_regulation of Cd4 80 0.51 61.32 8.51 82.32
69 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 82.12
70 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 82.12
71 INT230440 Gene_expression of HAUS7 1 0.04 4.13 1.02 81.64
72 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 81.52
73 INT6852 Localization of TNF 883 0.81 705.95 270.84 81.24
74 INT85415 Positive_regulation of IL9 10 0.28 6.93 4.71 81.04
75 INT18524 Regulation of Gene_expression of IFNA1 37 0.44 18.79 7.62 81.00
76 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 80.52
77 INT300648 Positive_regulation of Phosphorylation of Tmie 1 0.25 0.57 0.4 80.24
78 INT300650 Phosphorylation of Tmie 1 0.41 0.57 0.4 80.24
79 INT104392 Gene_expression of Cxcl10 113 0.75 106.86 34.12 79.48
80 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 79.24
81 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 78.68
82 INT273283 Negative_regulation of Tmie 4 0.25 1.69 0.84 78.64
83 INT181402 Negative_regulation of Ccr1 8 0.42 7 2.2 78.36
84 INT112969 Negative_regulation of Mcpt1 30 0.45 20.17 10.11 77.88
85 INT104394 Positive_regulation of Gene_expression of Cxcl10 28 0.65 25.64 8.79 76.72
86 INT194770 Positive_regulation of Phosphorylation of HNRNPA0 1 0.25 0.45 0.33 76.16
87 INT50380 Gene_expression of Cpm 7 0.73 4.43 3.38 76.00
88 INT194772 Binding of CXCL2 1 0.07 0.22 0.13 74.96
89 INT81194 Binding of CPOX 40 0.29 23.7 18.95 73.52
90 INT6481 Binding of TNF 624 0.48 510.2 214.82 73.12
91 INT194781 Phosphorylation of HNRNPA0 1 0.41 0.42 0.27 70.08
92 INT9660 Regulation of TNF 363 0.62 312.94 139.99 69.04
93 INT14700 Regulation of IFNA1 111 0.45 66.16 21.52 69.04
94 INT2152 Transcription of Cpm 2 0.66 1.3 0.5 66.64
95 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 63.80
96 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29 63.48
97 INT80549 Binding of ICAM1 53 0.47 42.76 9.72 60.48
98 INT88701 Gene_expression of MMD 15 0.44 6.04 1.94 60.16
99 INT183065 Positive_regulation of Gene_expression of PDX1 7 0.54 6.58 1.29 59.32
100 INT170854 Gene_expression of CFD 26 0.68 39.77 4.74 58.04
101 INT9110 Binding of PAH 32 0.41 42.1 3.1 54.24
102 INT65713 Localization of ICAM1 42 0.81 39.55 11.49 53.60
103 INT10834 Binding of IL8 65 0.48 41.66 16.53 52.32
104 INT115622 Positive_regulation of Binding of IL8 7 0.44 5.79 2.69 52.32
105 INT86437 Binding of IL6 154 0.48 121.22 29.3 51.76
106 INT87062 Positive_regulation of Binding of IL6 10 0.49 11.8 1.42 51.76
107 INT194794 Binding of TTPA 7 0.08 2.56 0.57 51.68
108 INT303885 Negative_regulation of Serpinh1 5 0.05 1.68 0.7 50.08
109 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 44.32
110 INT63338 Regulation of Gene_expression of ICAM1 42 0.62 28.26 9.06 44.32
111 INT125312 Positive_regulation of COPD 134 0.59 162.55 20.27 43.68
112 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 39.16
113 INT131433 Phosphorylation of MAPKAPK2 3 0.30 0.99 0.73 34.88
114 INT194774 Phosphorylation of TTPA 1 0.06 0.62 0.4 34.32
115 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 34.04
116 INT213217 Negative_regulation of Binding of PAH 2 0.32 2.03 0.19 32.64
117 INT171059 Localization of PDX1 8 0.56 6.7 1.9 31.92
118 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 24.56
119 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 24.56
120 INT69952 Positive_regulation of IK 45 0.32 16.08 14.59 24.56
121 INT194777 Positive_regulation of Phosphorylation of TTPA 1 0.03 0.09 0.16 24.40
122 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 23.72
123 INT194790 Positive_regulation of Phosphorylation of MAPKAPK2 1 0.19 0.09 0.16 21.92
124 INT70970 Binding of COPD 144 0.42 180.34 18.29 21.80
125 INT23401 Gene_expression of HLA-DOA 91 0.30 38.21 5.52 20.84
126 INT63341 Negative_regulation of ICAM1 42 0.59 30.45 9.5 19.84
127 INT22045 Gene_expression of IRF6 158 0.75 58.07 27.81 17.68
128 INT57274 Positive_regulation of Gene_expression of COL7A1 50 0.69 24.19 4.72 17.44
129 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 16.96
130 INT134651 Binding of TLR4 89 0.48 66.96 23.19 16.24
131 INT99586 Binding of IRF6 60 0.36 27.87 13.2 15.32
132 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 15.08
133 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 12.96
134 INT150540 Binding of TLR2 50 0.45 35.86 10.43 12.16
135 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23 10.32
136 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31 10.32
137 INT197156 Binding of CAPN7 2 0.27 1.89 0 10.00
138 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 8.08
139 INT151468 Regulation of MAP2K6 2 0.11 0.68 0.74 6.72
140 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
141 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
142 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
143 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
144 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
145 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
146 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 5.00
147 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
148 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 5.00
149 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 5.00
150 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
151 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 5.00
152 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 5.00
153 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
154 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
155 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
156 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 5.00
157 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
158 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
159 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 5.00
160 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
161 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 5.00
162 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
163 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 5.00
164 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 5.00
165 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 5.00
166 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 5.00
167 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
168 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 5.00
169 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 5.00
170 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72 5.00
171 INT72182 Gene_expression of Mcpt1 167 0.75 123.7 52.15 5.00
172 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 5.00
173 INT9210 Regulation of IL6 166 0.62 125.61 49.95 5.00
174 INT35975 Regulation of Cpox 109 0.39 57.88 49.69 5.00
175 INT7093 Negative_regulation of CYP2B6 146 0.58 37.3 48.39 5.00
176 INT117598 Regulation of ACR 118 0.26 41.25 48.01 5.00
177 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17 5.00
178 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 5.00
179 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22 5.00
180 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 5.00
181 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
182 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 5.00
183 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 5.00
184 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 5.00
185 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
186 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
187 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 5.00
188 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
189 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 5.00
190 INT80690 Positive_regulation of MAPK8 223 0.68 125.63 36.75 5.00
191 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54 5.00
192 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
193 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 5.00
194 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 5.00
195 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 5.00
196 INT666 Gene_expression of Jun 124 0.78 54.61 33.67 5.00
197 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 5.00
198 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4 5.00
199 INT132161 Gene_expression of MTX1 48 0.58 26.55 32.32 5.00
200 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 5.00
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