D:Hypertensive Encephalopathy

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms ENCEPHALOPATHY HYPERTENSIVE
Documents 138
Hot Single Events 11
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hypertensive Encephalopathy. They are ordered first by their relevance to Hypertensive Encephalopathy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT277835 EPO Positive_regulation of Localization of VEGFA 1 0.03 1.36 0.08 24.84
2 INT175401 Binding of EGFR and VEGFA 2 0.13 1.49 0.13 5.00
3 INT250661 Binding of EGF and ERBB2 2 0.11 0.82 0.08 5.00
4 INT185279 Binding of CCND1 and CDK4 4 0.13 2.05 0.08 5.00
5 INT185278 Binding of CCND1 and CDK6 3 0.13 1.62 0.08 5.00
6 INT250662 FNTA Positive_regulation of Positive_regulation of RASGRP1 1 0.00 0.79 0.07 5.00
7 INT351651 Enpep Positive_regulation of Agt 1 0.22 0.93 0.07 5.00
8 INT351655 Avp Positive_regulation of Agt 1 0.11 0.94 0.07 5.00
9 INT213903 Binding of EGFR and ERBB2 10 0.37 5.03 0.04 5.00
10 INT351652 Enpep Positive_regulation of Positive_regulation of Agt 1 0.19 0.05 0.04 5.00
11 INT327451 HTN1 Positive_regulation of Adra1a 1 0.00 1.36 0.03 5.00
12 INT351663 Binding of AGT and Agt 1 0.32 0.57 0.03 5.00
13 INT351653 Enpep Positive_regulation of Protein_catabolism of Agt 1 0.22 0.54 0.03 5.00
14 INT250665 EGFR Positive_regulation of PIK3CB 1 0.21 1.39 0 5.00
15 INT250656 ELK1 Positive_regulation of Gene_expression of VEGFA 1 0.07 0.74 0 5.00
16 INT250659 Negative_regulation of PTEN Positive_regulation of Positive_regulation of PIK3CB 1 0.02 1.18 0 5.00
17 INT250668 AKT1 Positive_regulation of MTOR 1 0.16 1.26 0 5.00
18 INT250658 FOS Positive_regulation of CCND1 1 0.03 0.6 0 5.00
19 INT250667 KLF1 Regulation of ERBB2 1 0.00 1.16 0 5.00
20 INT250663 Phosphorylation of AKT1 Positive_regulation of MTOR 1 0.16 1.26 0 5.00
21 INT250666 ERBB2 Positive_regulation of PIK3CB 1 0.15 0.69 0 5.00
22 INT351656 Enpep Regulation of Agt 1 0.20 1.2 0 5.00
23 INT250718 PIK3CB Regulation of Gene_expression of Birc5 1 0.23 0.91 0 5.00
24 INT250657 STAT3 Positive_regulation of Gene_expression of VEGFA 1 0.07 0.74 0 5.00
25 INT277836 EGFR Positive_regulation of VEGFA 1 0.24 0.47 0 5.00
26 INT187640 Binding of EGFR and KLF1 3 0.01 2.54 0 5.00
27 INT250664 PIK3CB Positive_regulation of AKT1 1 0.09 0.62 0 5.00
28 INT250660 PIK3CB Negative_regulation of AKT1 1 0.09 0.83 0 5.00
29 INT351650 Enpep Regulation of Protein_catabolism of Agt 1 0.20 0.35 0 5.00
30 INT250669 Binding of TP53 and ST8SIA4 1 0.02 0.51 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hypertensive Encephalopathy. They are ordered first by their pain relevance and then by number of times they were reported in Hypertensive Encephalopathy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT111032 Binding of ACOT8 1 0.36 1.51 0.18 99.82
2 INT239215 Binding of Agt 9 0.38 6.75 1.35 97.88
3 INT351642 Negative_regulation of Binding of Agt 1 0.34 0.88 0 97.88
4 INT164617 Protein_catabolism of Agt 2 0.79 5.3 0.25 94.68
5 INT248073 Gene_expression of HSD17B4 2 0.65 2.67 0.22 87.92
6 INT230806 Positive_regulation of Gene_expression of Agt 11 0.55 16.08 0.83 84.36
7 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 84.24
8 INT148071 Gene_expression of Agt 42 0.74 44.9 2.43 83.96
9 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 83.20
10 INT312273 Binding of HSD17B4 1 0.36 0.81 0.07 83.04
11 INT45503 Binding of EPO 42 0.48 24.85 2.88 82.80
12 INT13400 Negative_regulation of Enpep 30 0.50 4.23 15.86 74.40
13 INT27670 Negative_regulation of Ace 122 0.57 79.21 18.08 59.92
14 INT229279 Negative_regulation of Cby1 15 0.42 9.4 0.31 59.92
15 INT2824 Positive_regulation of HTN1 10 0.40 10.41 1.4 48.52
16 INT2630 Positive_regulation of Shbg 134 0.70 65.26 15.19 47.52
17 INT2629 Localization of Shbg 27 0.72 15.12 3.2 47.52
18 INT2628 Positive_regulation of Localization of Shbg 4 0.13 4.22 0.32 47.52
19 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 42.56
20 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 41.60
21 INT60040 Negative_regulation of Negative_regulation of Ace 6 0.43 3.64 0.38 38.48
22 INT327416 Localization of Apeh 1 0.07 2.19 0.14 37.96
23 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 34.40
24 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 34.40
25 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 34.28
26 INT44817 Negative_regulation of Gene_expression of Shbg 9 0.34 9.84 1.11 34.04
27 INT9832 Gene_expression of Shbg 96 0.75 56.71 12.19 32.92
28 INT654 Localization of REN 250 0.81 75.12 47.86 31.12
29 INT105210 Positive_regulation of Adrm1 7 0.06 4.09 0.5 27.20
30 INT2330 Regulation of CB 78 0.10 20.46 32.6 25.00
31 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 25.00
32 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 23.80
33 INT100222 Binding of Src 9 0.26 5.41 5.37 23.40
34 INT156351 Positive_regulation of Flt1 22 0.51 20.05 0.91 21.72
35 INT351647 Positive_regulation of Tie1 1 0.04 1.39 0.04 21.72
36 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79 17.48
37 INT351643 Negative_regulation of Positive_regulation of Pgf 1 0.17 2.66 0.08 17.48
38 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 16.96
39 INT260822 Positive_regulation of Pgf 7 0.36 3.36 0.72 16.96
40 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 15.28
41 INT6405 Gene_expression of Enpep 9 0.67 4.79 3.4 12.72
42 INT351637 Positive_regulation of Gene_expression of Enpep 1 0.24 0.91 0 12.72
43 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 6.12
44 INT21788 Positive_regulation of ERBB2 49 0.66 28.88 1.68 6.12
45 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 5.72
46 INT1177 Positive_regulation of Positive_regulation of Ren 16 0.70 6.11 3 5.60
47 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
48 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 5.00
49 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
50 INT7944 Positive_regulation of Fos 193 0.70 60.69 98.31 5.00
51 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 5.00
52 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42 5.00
53 INT11807 Gene_expression of Il2 266 0.78 112 64.97 5.00
54 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
55 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 5.00
56 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74 5.00
57 INT314 Positive_regulation of Ren 212 0.70 66.68 55.56 5.00
58 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 5.00
59 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
60 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 5.00
61 INT927 Gene_expression of Oxt 184 0.78 44.71 35.79 5.00
62 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
63 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 5.00
64 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 5.00
65 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 5.00
66 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 5.00
67 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47 5.00
68 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97 5.00
69 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85 5.00
70 INT21687 Positive_regulation of ras 143 0.58 97.34 27.31 5.00
71 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 5.00
72 INT11303 Gene_expression of Avp 116 0.78 39.23 23.88 5.00
73 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8 5.00
74 INT86534 Positive_regulation of MAPK14 81 0.62 57.81 23.62 5.00
75 INT50039 Positive_regulation of Il4 48 0.55 34.8 23.34 5.00
76 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 5.00
77 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52 5.00
78 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21 5.00
79 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22 5.00
80 INT116856 Gene_expression of TNFSF10 110 0.75 115.76 21.48 5.00
81 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
82 INT11157 Binding of EGF 88 0.48 53.73 21.25 5.00
83 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94 5.00
84 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 5.00
85 INT14701 Negative_regulation of IFNA1 118 0.54 84.19 20.08 5.00
86 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61 5.00
87 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 5.00
88 INT3060 Negative_regulation of Bche 94 0.59 46.75 18.51 5.00
89 INT1721 Negative_regulation of HP 148 0.42 86.82 16.89 5.00
90 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 5.00
91 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95 5.00
92 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59 5.00
93 INT75434 Gene_expression of Il13 27 0.52 26.19 15.4 5.00
94 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32 5.00
95 INT7776 Gene_expression of Abcb1b 63 0.75 21.35 14.92 5.00
96 INT153776 Positive_regulation of IL17A 42 0.64 34.58 14.82 5.00
97 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74 5.00
98 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 5.00
99 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 5.00
100 INT34904 Negative_regulation of Gtf3a 48 0.15 38.88 13.73 5.00
101 INT655 Positive_regulation of Localization of REN 86 0.70 32.41 13.56 5.00
102 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 5.00
103 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54 5.00
104 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18 5.00
105 INT8548 Gene_expression of HP 86 0.77 47.62 11.94 5.00
106 INT3602 Negative_regulation of Shbg 148 0.53 69.05 11.65 5.00
107 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55 5.00
108 INT661 Gene_expression of REN 100 0.78 48.21 11.36 5.00
109 INT8065 Binding of AGT 54 0.48 20.54 10.85 5.00
110 INT13499 Gene_expression of Agtr2 68 0.76 35.64 10.59 5.00
111 INT2378 Negative_regulation of SERPINE1 47 0.59 34.55 9.9 5.00
112 INT23676 Gene_expression of Chrna7 47 0.75 23.66 9.51 5.00
113 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01 5.00
114 INT13467 Positive_regulation of ABCB1 36 0.68 9.68 8.95 5.00
115 INT22798 Regulation of Shbg 64 0.60 26.71 8.76 5.00
116 INT10879 Positive_regulation of Avp 39 0.65 14.01 8.76 5.00
117 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68 5.00
118 INT8637 Negative_regulation of Dbp 112 0.50 33.28 8.4 5.00
119 INT156827 Localization of MRI1 25 0.65 16.06 8.33 5.00
120 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27 5.00
121 INT15687 Regulation of ESR1 91 0.60 40.42 7.95 5.00
122 INT25958 Regulation of Ace 26 0.59 11.88 7.87 5.00
123 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59 5.00
124 INT11441 Negative_regulation of Anpep 18 0.59 3.73 7.51 5.00
125 INT96994 Phosphorylation of EGFR 99 0.82 52.75 7.33 5.00
126 INT70814 Negative_regulation of Il2 40 0.56 13.36 7.22 5.00
127 INT168915 Gene_expression of Oxtr 49 0.75 20.53 7.22 5.00
128 INT30443 Positive_regulation of AIS 30 0.54 22.59 7.2 5.00
129 INT147583 Gene_expression of AIS 82 0.58 48.7 7.11 5.00
130 INT84685 Regulation of BCL2 67 0.60 72.96 6.65 5.00
131 INT11154 Binding of EGFR 149 0.48 96.23 6.29 5.00
132 INT15775 Positive_regulation of Ren1 50 0.69 22.38 6.19 5.00
133 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14 5.00
134 INT93684 Gene_expression of STAT3 66 0.78 34.42 5.94 5.00
135 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93 5.00
136 INT63177 Regulation of HP 71 0.44 39.48 5.86 5.00
137 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78 5.00
138 INT112124 Positive_regulation of Egfr 71 0.70 47.82 5.61 5.00
139 INT21103 Gene_expression of Dbp 48 0.61 22.6 5.59 5.00
140 INT21609 Positive_regulation of RASGRP1 58 0.50 40.78 5.47 5.00
141 INT125066 Negative_regulation of HDAC4 56 0.49 41.55 5.42 5.00
142 INT87420 Gene_expression of BCL2L1 56 0.75 48.84 5.32 5.00
143 INT75682 Regulation of Chrna7 14 0.45 10.24 5.25 5.00
144 INT60585 Regulation of TP53 59 0.59 54.55 5.21 5.00
145 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19 5.00
146 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07 5.00
147 INT19993 Negative_regulation of Ren1 43 0.58 20.89 5.04 5.00
148 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 5.00
149 INT105336 Regulation of AKT1 52 0.56 32.53 4.89 5.00
150 INT24889 Negative_regulation of CABIN1 36 0.48 16.76 4.73 5.00
151 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 5.00
152 INT51030 Negative_regulation of LMOD1 9 0.44 5.83 4.58 5.00
153 INT29231 Regulation of Dbp 44 0.53 10.08 4.47 5.00
154 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45 5.00
155 INT80983 Regulation of Abcb1b 16 0.60 1.95 4.32 5.00
156 INT84686 Regulation of BAX 26 0.49 28.54 4.13 5.00
157 INT182311 Positive_regulation of Birc5 26 0.67 25.32 4.08 5.00
158 INT81688 Binding of ras 32 0.41 30.13 4.02 5.00
159 INT156131 Binding of Hand2 14 0.25 10.35 3.99 5.00
160 INT88414 Negative_regulation of CDK2 30 0.57 18.4 3.96 5.00
161 INT101857 Negative_regulation of BCL2L1 22 0.57 23.56 3.95 5.00
162 INT80421 Positive_regulation of IFI27 26 0.65 15.32 3.93 5.00
163 INT163832 Negative_regulation of Gene_expression of EGFR 50 0.59 39.71 3.45 5.00
164 INT75500 Negative_regulation of Gene_expression of CCND1 21 0.57 11.59 3.24 5.00
165 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21 5.00
166 INT120562 Negative_regulation of Egfr 108 0.59 79.38 3.11 5.00
167 INT117348 Regulation of EGFR 75 0.61 47.73 3.09 5.00
168 INT8103 Binding of TP53 46 0.44 40.2 2.96 5.00
169 INT140547 Negative_regulation of PSMB10 3 0.02 2.33 2.92 5.00
170 INT41721 Negative_regulation of MTOR 40 0.58 32.49 2.83 5.00
171 INT8095 Gene_expression of ERBB3 47 0.77 24.85 2.82 5.00
172 INT89401 Negative_regulation of Phosphorylation of AKT1 68 0.58 35.61 2.8 5.00
173 INT116463 Negative_regulation of Gene_expression of Birc5 40 0.59 33.99 2.74 5.00
174 INT11300 Positive_regulation of Gene_expression of Avp 24 0.50 10.18 2.69 5.00
175 INT14447 Localization of F2 20 0.79 12.77 2.67 5.00
176 INT53780 Binding of Avp 19 0.48 6.16 2.55 5.00
177 INT55952 Transcription of TP53 16 0.61 12.14 2.36 5.00
178 INT74695 Gene_expression of Ace 41 0.73 53.33 2.33 5.00
179 INT182312 Positive_regulation of Gene_expression of Birc5 26 0.69 25.3 2.32 5.00
180 INT82798 Regulation of MYC 19 0.60 12.06 2.31 5.00
181 INT29402 Gene_expression of Src 16 0.74 4.57 2.29 5.00
182 INT182318 Regulation of Birc5 25 0.60 23.58 2.29 5.00
183 INT27988 Negative_regulation of Positive_regulation of AGT 11 0.42 5.71 2.27 5.00
184 INT60279 Gene_expression of VHL 70 0.78 75.21 2.21 5.00
185 INT120650 Negative_regulation of UPF1 14 0.02 6.86 2.14 5.00
186 INT12061 Negative_regulation of LNPEP 19 0.58 5.52 2.14 5.00
187 INT101866 Positive_regulation of Gene_expression of AKT1 49 0.52 17.47 2.14 5.00
188 INT9908 Negative_regulation of IAPP 29 0.57 19.37 2.12 5.00
189 INT27989 Positive_regulation of Gene_expression of REN 18 0.55 12.69 2.11 5.00
190 INT104402 Positive_regulation of CCND1 15 0.70 11.77 2.08 5.00
191 INT138490 Positive_regulation of Il13 9 0.36 5.42 2.06 5.00
192 INT79915 Positive_regulation of Agt 27 0.56 12.97 1.96 5.00
193 INT129239 Positive_regulation of Positive_regulation of Hand2 5 0.43 2.81 1.93 5.00
194 INT136503 Negative_regulation of KDR 46 0.48 43.1 1.86 5.00
195 INT48722 Negative_regulation of Gene_expression of SERPINE1 12 0.43 7.66 1.85 5.00
196 INT125865 Regulation of TNFSF10 12 0.44 15.75 1.81 5.00
197 INT300417 Localization of Tyr 5 0.11 0.26 1.65 5.00
198 INT94169 Negative_regulation of Phosphorylation of RB1 16 0.41 8.87 1.57 5.00
199 INT110201 Positive_regulation of Sbp 10 0.49 5.25 1.55 5.00
200 INT118292 Negative_regulation of Phosphorylation of EGFR 27 0.59 13.62 1.54 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox