D:Hypertensive Nephropathy

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pChart

Disease Term
Synonyms HYPERTENSIVE NEPHROSCLEROSIS, Hypertensive Renal Disease
Documents 19
Hot Single Events 4
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hypertensive Nephropathy. They are ordered first by their relevance to Hypertensive Nephropathy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT291625 Binding of CSTA and RAPGEF5 1 0.03 4.81 0.37 84.32
2 INT291623 Binding of CRP and CSTA 1 0.03 0.38 0 17.20
3 INT291622 HSD11B1 Regulation of CSTA 1 0.00 0.6 0.11 5.00
4 INT291624 SERPINH1 Regulation of CSTA 1 0.00 0.39 0.09 5.00
5 INT291621 RAPGEF5 Regulation of CSTA 1 0.04 0.43 0.03 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hypertensive Nephropathy. They are ordered first by their pain relevance and then by number of times they were reported in Hypertensive Nephropathy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT44972 Negative_regulation of Gfra1 16 0.58 10.17 0.93 93.76
2 INT243382 Positive_regulation of CSTA 4 0.05 14.65 0.12 92.64
3 INT4679 Negative_regulation of RAPGEF5 55 0.57 47.51 4.55 80.24
4 INT11118 Gene_expression of RAPGEF5 13 0.65 9.35 0.43 80.24
5 INT259952 Negative_regulation of Negative_regulation of ALB 1 0.42 1.24 0.04 64.80
6 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 64.52
7 INT346335 Positive_regulation of Negative_regulation of Gfra1 1 0.02 1.47 0.04 57.80
8 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 48.84
9 INT57643 Negative_regulation of Binding of Ins1 6 0.43 3.51 0.43 43.36
10 INT2578 Binding of Ins1 74 0.48 33.57 12.92 43.00
11 INT63035 Gene_expression of CSTA 10 0.56 11.56 0.57 33.96
12 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 23.84
13 INT18773 Localization of ALB 117 0.80 69.18 13.8 23.84
14 INT63036 Negative_regulation of CSTA 4 0.36 9.42 0.22 18.32
15 INT4681 Localization of RAPGEF5 12 0.68 8.69 0.93 13.04
16 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 5.00
17 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 5.00
18 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
19 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
20 INT654 Localization of REN 250 0.81 75.12 47.86 5.00
21 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 5.00
22 INT234 Binding of Alb 151 0.48 52.34 32.97 5.00
23 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
24 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54 5.00
25 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 5.00
26 INT20585 Gene_expression of Gfra1 39 0.77 26.94 26.69 5.00
27 INT3559 Negative_regulation of Localization of Gnrhr 73 0.58 18.89 26.41 5.00
28 INT23257 Regulation of CRP 127 0.62 100.05 21.87 5.00
29 INT653 Negative_regulation of Localization of REN 67 0.59 20.33 16.7 5.00
30 INT22083 Regulation of Pth 55 0.62 22.32 8.9 5.00
31 INT15687 Regulation of ESR1 91 0.60 40.42 7.95 5.00
32 INT17996 Binding of Crp 40 0.37 31.4 7.8 5.00
33 INT9321 Transcription of Igf1 25 0.69 10.2 6.08 5.00
34 INT30738 Negative_regulation of Gene_expression of ALB 32 0.59 19.01 5.04 5.00
35 INT4097 Localization of Pth 66 0.81 47.17 4.36 5.00
36 INT95512 Transcription of Ghr 24 0.69 3.1 4.12 5.00
37 INT91999 Transcription of Gfra1 10 0.67 4.67 2.45 5.00
38 INT35643 Positive_regulation of BPIFA4P 7 0.67 4.87 2.39 5.00
39 INT165841 Gene_expression of BPIFA4P 17 0.65 6.48 2.38 5.00
40 INT47734 Positive_regulation of RAPGEF5 19 0.56 13.16 1.41 5.00
41 INT39500 Positive_regulation of Positive_regulation of Pth 14 0.48 9.75 1.28 5.00
42 INT188774 Binding of RAPGEF5 12 0.29 13.55 1.04 5.00
43 INT63037 Regulation of CSTA 10 0.37 13.37 0.92 5.00
44 INT62067 Negative_regulation of Gene_expression of Pth 13 0.41 8.24 0.61 5.00
45 INT19395 Negative_regulation of Localization of Pth 11 0.58 10.16 0.55 5.00
46 INT127291 Transcription of ALB 7 0.67 4.26 0.55 5.00
47 INT36770 Positive_regulation of Localization of Pth 14 0.70 10.42 0.46 5.00
48 INT291629 Localization of CSTA 1 0.08 1.05 0.11 5.00
49 INT291628 Positive_regulation of Gene_expression of CSTA 1 0.05 0.52 0.09 5.00
50 INT291627 Binding of CSTA 2 0.04 1.58 0.08 5.00
51 INT291630 Regulation of Gene_expression of CSTA 2 0.06 1.01 0.08 5.00
52 INT214037 Positive_regulation of Positive_regulation of BPIFA4P 2 0.11 1.36 0.05 5.00
53 INT346340 Regulation of Gene_expression of BPIFA4P 1 0.06 0.68 0 5.00
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