D:Hypertrophy

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Disease Term
Synonyms HYPERTROPHIES
Documents 2129
Hot Single Events 200
Hot Interactions 127

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hypertrophy. They are ordered first by their relevance to Hypertrophy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT259703 Binding of MYBPC3 and HELT 1 0.04 1.64 0 100.00
2 INT247851 Negative_regulation of Aqp4 Negative_regulation of Positive_regulation of Narfl 1 0.09 1.78 0.15 100.00
3 INT201147 Binding of Slc5a7 and Ryr2 1 0.07 0.23 0 100.00
4 INT195121 Gene_expression of Il1r1 Positive_regulation of Positive_regulation of Gopc 1 0.17 0.26 0.11 100.00
5 INT195119 Gene_expression of Il1r1 Positive_regulation of Positive_regulation of Gfap 1 0.38 0.26 0.11 100.00
6 INT241778 AVP Positive_regulation of AVPR1A 1 0.10 1.32 0 100.00
7 INT312223 INPP5K Negative_regulation of Gene_expression of COL10A1 1 0.04 0.1 0 100.00
8 INT312216 INPP5K Negative_regulation of Gene_expression of RUNX2 1 0.15 0.1 0 100.00
9 INT312215 INPP5K Negative_regulation of COL10A1 1 0.03 0.1 0 99.96
10 INT286113 Binding of Fap and Rpe65 1 0.04 1.97 0 99.84
11 INT286110 Binding of Rpe65 and Gopc 1 0.01 1.97 0 99.84
12 INT317566 Car2 Positive_regulation of Camk2a 2 0.19 0.58 0.32 99.82
13 INT295577 Gene_expression of Mstn Positive_regulation of Phosphorylation of Akt1 1 0.21 0.1 0 99.34
14 INT179094 Gene_expression of Myc Positive_regulation of Vps54 1 0.02 0.54 0 99.04
15 INT230752 Gene_expression of Agtr2 Positive_regulation of Gene_expression of Mcpt1 1 0.01 1.34 0.3 98.92
16 INT181814 Gsk3b Regulation of Gata4 1 0.06 0.37 0.05 98.88
17 INT170841 Binding of CFD and IFI27 1 0.07 0.37 0 98.72
18 INT220192 PTGER2 Negative_regulation of Positive_regulation of TIMP1 1 0.04 0.99 0.22 98.48
19 INT201173 Sox2 Positive_regulation of Localization of Ryr2 1 0.40 0.9 0.07 98.44
20 INT201172 Sox2 Positive_regulation of Localization of Ca2 1 0.47 0.9 0.07 98.44
21 INT337692 Cyp2b2 Positive_regulation of Nr1i3 1 0.00 0.31 0.05 98.36
22 INT277610 Binding of Runx2 and Hdac4 1 0.32 0.78 0 98.20
23 INT337693 Cyp3a62 Positive_regulation of Nr1i3 1 0.01 0.31 0.05 98.16
24 INT257344 Gene_expression of Cyba Positive_regulation of Nox1 1 0.23 1.15 0 98.04
25 INT257346 Gene_expression of Lox Positive_regulation of Nox1 1 0.02 0.57 0 98.04
26 INT277611 Binding of Mef2c and Hdac4 1 0.34 1.12 0 97.80
27 INT311904 Smad2 Positive_regulation of Gene_expression of Smad1 1 0.13 0.44 0.03 97.32
28 INT295576 Binding of Dmd and Mstn 1 0.23 1.1 0 97.12
29 INT88773 Positive_regulation of Binding of AGT and Agtrap 1 0.01 0.88 0.05 97.00
30 INT303004 Adm Positive_regulation of Gsk3b 1 0.04 0.97 0 96.90
31 INT311909 Gene_expression of Smad6 Negative_regulation of Gene_expression of Col10a1 1 0.02 0.54 0.04 96.84
32 INT321723 Ins1 Positive_regulation of Gtf3a 1 0.00 0.34 0 96.72
33 INT321717 Positive_regulation of Ins1 Positive_regulation of Gtf3a 1 0.00 0.17 0 96.72
34 INT247855 Positive_regulation of Narfl Regulation of Aqp4 1 0.04 2.93 0.04 96.52
35 INT247850 Positive_regulation of Narfl Regulation of Ube4a 1 0.00 1.86 0 96.52
36 INT220190 PTGER2 Regulation of COL2A1 1 0.32 0.92 0.18 96.42
37 INT213264 INS Positive_regulation of Localization of IGF1 1 0.16 1.77 0 96.40
38 INT230748 Agtr2 Positive_regulation of Gene_expression of Ros1 2 0.05 1.04 0.23 96.24
39 INT184083 Positive_regulation of Gh Positive_regulation of Igf1 1 0.09 0.7 0.04 95.76
40 INT352496 AVP Regulation of Gene_expression of CRS 1 0.27 2.47 0.59 95.64
41 INT266417 Binding of TGM2 and S100a11 1 0.01 0.86 0.16 95.40
42 INT88774 Binding of AGT and Agtrap 2 0.01 2.13 0.03 95.24
43 INT88772 Negative_regulation of Binding of AGT and Agtrap 1 0.02 0.89 0.03 95.24
44 INT156668 Gh Positive_regulation of Igf1 5 0.22 2.07 0.57 95.08
45 INT257345 Ncf1 Positive_regulation of Gene_expression of Ros1 1 0.08 0.58 0 94.72
46 INT328381 Ghrl Positive_regulation of NPY 1 0.06 0.15 0.03 94.68
47 INT328369 Ghrl Negative_regulation of CRH 1 0.16 0.15 0 94.68
48 INT328375 Ghrl Negative_regulation of LEP 1 0.07 0.15 0 94.68
49 INT220195 PTGER2 Negative_regulation of Localization of COL2A1 1 0.26 0.51 0.09 94.56
50 INT300313 TGFB1 Positive_regulation of Mapk14 1 0.01 1.5 0.11 94.56
51 INT300306 Agt Positive_regulation of Mapk14 1 0.14 1.51 0.11 94.56
52 INT304776 Binding of KMS and KTWS 1 0.01 2.24 0 93.88
53 INT322237 Binding of Agtrap and Hcm 1 0.14 2.3 0.19 93.04
54 INT220196 Binding of PTGER2 and Negative_regulation of Gene_expression of COL2A1 1 0.26 0.77 0.04 93.00
55 INT299232 Onc1 Regulation of Gene_expression of Aqp4 1 0.01 0.43 0 92.44
56 INT303028 Binding of Pah and MCPH1 1 0.02 1.13 0.16 91.68
57 INT303399 Binding of Jag1 and Myh3 1 0.50 0.85 0 91.64
58 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11 91.60
59 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66 91.48
60 INT303394 Binding of Myh3 and Mul1 1 0.04 0.38 0 91.48
61 INT93614 Ngf Positive_regulation of Ntrk1 2 0.52 0.85 1.05 91.40
62 INT166247 Ngf Regulation of Ntrk1 1 0.05 0.09 0.38 91.40
63 INT166250 Ngf Regulation of Ngf Positive_regulation of Ntrk1 1 0.06 0.09 0.38 91.40
64 INT166251 Ngf Positive_regulation of Ngf Regulation of Ntrk1 1 0.10 0.09 0.38 91.40
65 INT164249 Binding of MPZ and Mpz 1 0.06 2.13 0.24 91.20
66 INT303003 Gene_expression of Ptgis Positive_regulation of Pah 1 0.36 1.67 0.13 91.16
67 INT303027 Gene_expression of MCPH1 Positive_regulation of Pah 1 0.02 0.83 0.07 91.16
68 INT303026 Gene_expression of MCPH1 Positive_regulation of Gene_expression of Ptgis 1 0.02 0.78 0.04 91.16
69 INT303008 Gene_expression of Pah Positive_regulation of Gene_expression of Ptgis 1 0.31 0.78 0.04 91.16
70 INT8928 Negative_regulation of Trpc4 Negative_regulation of Positive_regulation of Acta1 1 0.02 0.18 0.05 91.00
71 INT226209 Pik3cb Positive_regulation of Phosphorylation of Akt1 1 0.10 1.16 0.17 90.96
72 INT351982 Smarca4 Positive_regulation of Stk11 1 0.05 0.58 0 90.94
73 INT199977 ESR1 Positive_regulation of JUN 1 0.03 0.18 0 90.32
74 INT185654 DBT Negative_regulation of AR 1 0.02 0.09 0 90.00
75 INT184126 Gh Positive_regulation of Gene_expression of Socs2 1 0.14 1.25 0.08 89.92
76 INT184115 Igf1 Positive_regulation of Gene_expression of Socs2 1 0.16 0.62 0.04 89.92
77 INT188318 MCPH1 Positive_regulation of Pah 3 0.02 3 0.85 89.60
78 INT199988 ESR1 Positive_regulation of Fos 1 0.40 0.18 0 89.52
79 INT193033 Binding of CHRM1 and EGF 1 0.01 1.96 0.22 89.28
80 INT276887 MTOR Regulation of Ppargc1a 1 0.23 0.33 0 89.16
81 INT276868 MTOR Regulation of Gene_expression of MTUS1 1 0.01 0.33 0 89.16
82 INT184139 Gh Positive_regulation of Gh Positive_regulation of Stat5b 1 0.06 1.31 0.1 88.96
83 INT184089 Gh Positive_regulation of Stat5b 1 0.13 1.3 0.1 88.96
84 INT184140 Socs2 Negative_regulation of Gh Positive_regulation of Stat5b 1 0.10 1.33 0.1 88.96
85 INT328368 Ghrl Positive_regulation of INS 1 0.04 0.22 0 88.72
86 INT325606 Negative_regulation of Nppa Negative_regulation of Ang 1 0.25 0.46 0 88.48
87 INT325595 Nppa Negative_regulation of Ang 1 0.25 0.46 0 88.48
88 INT310275 Negative_regulation of Binding of Adipoq and Ins1 1 0.19 1.14 0.09 88.32
89 INT310274 Binding of Adipoq and Ins1 1 0.21 1.14 0.09 88.32
90 INT300307 Binding of Tp53 and Sirt1 1 0.24 0.98 0 88.08
91 INT220194 PTGER2 Negative_regulation of COL2A1 1 0.26 0.55 0.29 87.60
92 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28 86.60
93 INT224921 Binding of TTR and TARM1 1 0.06 1.06 0 86.48
94 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15 85.68
95 INT255761 hs Regulation of TNF 1 0.07 1.33 0 85.56
96 INT354619 AR Positive_regulation of Gene_expression of Nppa 1 0.00 0.38 0 85.44
97 INT255760 Ptch1 Regulation of TNF 1 0.13 1.33 0 85.44
98 INT305270 Lep Negative_regulation of Localization of Car2 1 0.16 1.28 0 85.32
99 INT298998 Il18 Positive_regulation of Cdk5 1 0.11 0.36 0.17 84.68
100 INT299001 Il18 Positive_regulation of Cdk5r1 1 0.03 0.36 0.17 84.68
101 INT177762 GOPC Negative_regulation of Gene_expression of CHKB 1 0.11 0.08 0 84.52
102 INT220193 PTGER2 Regulation of PTGES 1 0.06 0.66 0.41 84.32
103 INT309779 PTH Negative_regulation of Gene_expression of COL5A2 1 0.00 0.52 0.14 83.92
104 INT247848 Narfl Negative_regulation of Uchl1 1 0.03 0.74 0 83.92
105 INT184133 Binding of Gh and Socs2 1 0.10 0.66 0.05 83.84
106 INT178269 Slc11a2 Regulation of a 1 0.06 0.97 0.16 83.44
107 INT178266 Raly Regulation of a 1 0.14 0.97 0.16 83.44
108 INT303007 Binding of Pah and Ptgis 1 0.26 0.99 0.12 83.40
109 INT248244 Binding of IL8 and SDC2 1 0.02 1.57 0.72 83.36
110 INT178433 Fgf1 Positive_regulation of Mapk14 1 0.02 0.65 0 83.16
111 INT325598 Ang Positive_regulation of Camk2a 1 0.21 0.29 0 83.04
112 INT325601 Ang Positive_regulation of Phosphorylation of Camk2a 1 0.21 0.29 0 83.04
113 INT219596 Binding of Pde4a and Pde4d 1 0.28 0.31 0 82.96
114 INT295574 Binding of Igf1 and Mstn 1 0.16 0.08 0 82.36
115 INT276211 Pdpk1 Regulation of Akt1 1 0.07 0.72 0.04 82.12
116 INT150446 Binding of Clcn1 and Scn4a 1 0.26 0.65 0.08 82.04
117 INT193218 Binding of PTGER1 and PTGER2 3 0.12 2.31 0.66 81.80
118 INT246217 Cdkn1b Positive_regulation of VEGFA 1 0.03 1.13 0 81.64
119 INT246218 Fn1 Positive_regulation of VEGFA 1 0.03 1.13 0 81.64
120 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6 81.12
121 INT257870 Agt Positive_regulation of Akt1 2 0.18 1.5 0.09 81.12
122 INT325283 Negative_regulation of MCL1 Positive_regulation of Gene_expression of ADIPOQ 1 0.14 1.53 0 81.04
123 INT340568 Fgf1 Positive_regulation of Mapk1 1 0.06 1.02 0.04 80.56
124 INT303030 Binding of Ednra and MCPH1 1 0.00 1.02 0.32 80.48
125 INT303005 Binding of Ednra and Pah 1 0.06 1.02 0.32 80.48
126 INT282421 Mapk8 Negative_regulation of Ins1 1 0.06 2.48 0.31 80.48
127 INT172835 Binding of AGT and T2dm2 1 0.00 1.73 0 80.16
128 INT255747 hs Positive_regulation of Phosphorylation of Gopc 1 0.07 1.33 0 79.76
129 INT255752 hs Positive_regulation of Phosphorylation of Slc2a4 1 0.08 1.32 0 79.76
130 INT255753 Ptch1 Positive_regulation of Phosphorylation of Gopc 1 0.13 1.33 0 79.64
131 INT255749 Ptch1 Positive_regulation of Phosphorylation of Slc2a4 1 0.15 1.32 0 79.64
132 INT172839 Binding of ANGPT2 and T2dm2 1 0.00 1.72 0 79.52
133 INT157459 Binding of CX3CR1 and CX3CL1 1 0.32 2.12 1.7 79.28
134 INT246841 Binding of Irs1 and Ppp1r13b 5 0.16 0.94 0.28 79.08
135 INT321720 Binding of Ppp1r13b and Irs2 1 0.11 0.13 0 78.72
136 INT303866 Positive_regulation of NAA50 Negative_regulation of Gene_expression of CACNA1C 1 0.13 0.08 0.16 78.40
137 INT197072 Binding of Slc3a1 and Atr 1 0.07 0.32 0.13 77.96
138 INT249995 Positive_regulation of Binding of ICAM1 and GPHA2 1 0.02 2.43 0 77.76
139 INT299004 Binding of Il18 and Il1 1 0.04 1.16 0.58 77.72
140 INT281479 Drd2 Positive_regulation of Penk 1 0.23 0.4 1.3 77.68
141 INT281482 Drd2 Positive_regulation of Drd2 Positive_regulation of Penk 1 0.21 0.27 0.87 77.68
142 INT290435 Positive_regulation of Binding of Mtor and Utp3 1 0.01 0.26 0 77.12
143 INT290436 Binding of Mtor and Utp3 1 0.00 0.26 0 77.12
144 INT171164 Agt Regulation of Positive_regulation of Rorb 1 0.02 0.64 0.1 77.04
145 INT325591 Olfml3 Positive_regulation of Camk2a 1 0.01 0.26 0 76.24
146 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03 76.16
147 INT249996 Binding of ICAM1 and GPHA2 1 0.02 2.25 0 76.08
148 INT293114 Fig4 Regulation of Gene_expression of Aqp2 1 0.08 1.53 0 75.48
149 INT293124 Agtr1a Regulation of Gene_expression of Aqp2 1 0.17 0.36 0.14 75.48
150 INT293125 Agt Regulation of Avp Regulation of Aqp2 1 0.04 0.36 0.14 75.48
151 INT293119 Agtr1a Regulation of Positive_regulation of Crh 1 0.12 0.37 0.14 75.48
152 INT293115 Agt Regulation of Positive_regulation of Crh 1 0.16 0.37 0.14 75.48
153 INT293117 Agt Regulation of Gene_expression of Aqp2 1 0.23 0.36 0.14 75.48
154 INT293126 Agtr1a Regulation of Avp Regulation of Aqp2 1 0.03 0.36 0.14 75.48
155 INT293123 Agtr1a Regulation of Negative_regulation of Agt 1 0.14 0.25 0.14 75.48
156 INT189550 Binding of BMPR2 and PAH 1 0.06 2.68 0.08 75.44
157 INT303029 Binding of TEK and Angpt1 1 0.26 1.82 0.22 75.08
158 INT325607 Positive_regulation of Gopc Regulation of Ang 1 0.15 0.26 0 75.04
159 INT310280 Gpt Positive_regulation of SLPI 1 0.30 0.43 0 73.80
160 INT226205 Negative_regulation of Akt1 Positive_regulation of Casp3 1 0.04 0.71 0.14 73.60
161 INT321714 Slc10a3 Positive_regulation of Binding of Akt1 1 0.08 0.22 0 73.48
162 INT310279 Tmprss11d Positive_regulation of SLPI 1 0.18 0.43 0 73.16
163 INT296893 Nps Negative_regulation of Gene_expression of REN 1 0.00 1.05 0.04 72.92
164 INT325590 Gopc Regulation of Ang 1 0.13 0.25 0 72.52
165 INT230019 Binding of HLA-B and ERAL1 1 0.00 2.23 1.1 72.24
166 INT276216 Binding of Akt1 and Ins1 2 0.03 2.61 0.4 72.08
167 INT304813 Binding of MNX1 and RT1-CE1 1 0.00 0.34 0.1 71.76
168 INT328373 Negative_regulation of Ghrl Positive_regulation of Localization of GH1 1 0.05 0.31 0.08 71.44
169 INT182804 Binding of ETV3 and T2DM 1 0.10 2.62 0 71.16
170 INT257341 Binding of Neu2 and Cyba 1 0.00 0.29 0 71.12
171 INT257347 Binding of Cyba and Ncf1 1 0.17 0.29 0 71.12
172 INT257340 Binding of Cyba and Rac1 1 0.09 0.29 0 71.12
173 INT293118 Avp Regulation of Aqp2 1 0.04 0.7 0.27 70.72
174 INT224922 Binding of FAP and TARM1 1 0.06 1.4 0.06 70.72
175 INT247843 Narfl Regulation of Aqp4 1 0.04 1.07 0.04 70.08
176 INT303857 DDR1 Positive_regulation of IL8 1 0.05 1.5 0.42 69.76
177 INT303858 DDR1 Positive_regulation of CXCR2 1 0.11 1.5 0.42 69.56
178 INT11124 Nppa Negative_regulation of Thop1 Positive_regulation of Nppa 1 0.23 0.4 0 69.52
179 INT11122 Nppa Negative_regulation of Thop1 1 0.20 0.4 0 69.52
180 INT247847 Narfl Positive_regulation of Positive_regulation of Casp3 1 0.02 0.79 0 68.68
181 INT255751 hs Regulation of Ins1 1 0.05 1.24 0 68.36
182 INT255734 Ptch1 Regulation of Ins1 1 0.09 1.46 0 68.24
183 INT271452 Binding of TGFB1 and Eln 1 0.00 0.38 0.04 67.68
184 INT271449 Binding of TGFB1 and Lox 1 0.01 0.38 0.04 67.68
185 INT351974 Agt Positive_regulation of Gene_expression of Stk11 1 0.51 11.1 0.12 67.52
186 INT321722 Negative_regulation of Binding of Irs1 and Ppp1r13b 1 0.20 0.07 0 66.52
187 INT350257 Slc12a6 Negative_regulation of Pnlip 1 0.03 1.53 0.03 66.48
188 INT301471 Binding of Smyd1 and Smyd2 1 0.40 0.2 0 66.24
189 INT247846 Positive_regulation of Narfl Positive_regulation of Positive_regulation of Ube4a 1 0.00 0.82 0 66.16
190 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8 65.52
191 INT336129 Binding of ANG and EXTL3 1 0.01 0.38 0 64.76
192 INT336131 Binding of ANG and ATP6AP2 1 0.00 0.38 0 64.76
193 INT336130 Binding of ANG and REN 1 0.06 0.38 0 64.76
194 INT182778 IGF1 Positive_regulation of Gene_expression of ETV3 1 0.03 1.89 0 64.56
195 INT182783 INS Positive_regulation of Gene_expression of ETV3 1 0.01 1.89 0 64.56
196 INT182777 IAPP Positive_regulation of Gene_expression of ETV3 1 0.06 1.88 0 64.56
197 INT230751 Agtr2 Positive_regulation of Gene_expression of Serpine1 1 0.03 1.3 0.23 64.24
198 INT281477 Binding of Pten and Th 1 0.28 0.4 0.19 64.24
199 INT300304 Positive_regulation of Mapk14 Positive_regulation of Agt 1 0.14 1.5 0.08 64.24
200 INT300305 Mapk14 Positive_regulation of Gene_expression of Ctgf 1 0.19 1.25 0.17 63.80

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hypertrophy. They are ordered first by their pain relevance and then by number of times they were reported in Hypertrophy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 100.00
2 INT14546 Positive_regulation of Localization of Ca2 93 0.67 31.09 18.72 100.00
3 INT49468 Negative_regulation of Pah 28 0.55 24.95 6.29 100.00
4 INT201157 Positive_regulation of Slc5a7 1 0.19 2.94 0.24 100.00
5 INT207426 Gene_expression of COL10A1 27 0.65 12.02 3.85 100.00
6 INT46028 Negative_regulation of Slc5a7 5 0.38 2.37 1.41 100.00
7 INT91370 Phosphorylation of STAT3 123 0.82 49.25 8.42 100.00
8 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 100.00
9 INT217742 Positive_regulation of Gene_expression of COL2A1 20 0.67 9.76 4.23 100.00
10 INT220211 Gene_expression of RUNX2 7 0.71 7.31 2 100.00
11 INT20415 Binding of LIPH 1 0.34 1.25 0.1 100.00
12 INT25479 Regulation of Slc5a7 2 0.17 0.85 0.13 100.00
13 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98 100.00
14 INT220203 Positive_regulation of Gene_expression of RUNX2 3 0.63 3.4 0.97 100.00
15 INT207429 Positive_regulation of Gene_expression of COL10A1 8 0.42 4.16 1.34 100.00
16 INT157691 Regulation of Gene_expression of Fbxo32 1 0.31 0.73 0.22 100.00
17 INT10923 Positive_regulation of Lipg 30 0.50 22.87 4.26 100.00
18 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 100.00
19 INT153077 Positive_regulation of Gene_expression of Nppa 9 0.40 5.07 0.13 100.00
20 INT19849 Positive_regulation of Smc1b 8 0.50 4.09 1.01 100.00
21 INT5536 Regulation of NA 74 0.59 16.61 15.36 100.00
22 INT1898 Regulation of Crh 220 0.62 61.33 102.64 100.00
23 INT6765 Localization of Oprl1 49 0.81 5.11 28.87 100.00
24 INT283374 Positive_regulation of Mstn 1 0.30 0.32 0 100.00
25 INT166432 Positive_regulation of Atp2a2 5 0.44 0.45 0.24 100.00
26 INT238158 Phosphorylation of Sik1 1 0.06 0.69 0.03 100.00
27 INT50558 Negative_regulation of PCNA 31 0.57 13.97 2.3 100.00
28 INT122037 Regulation of Ppara 93 0.62 56.28 12.89 100.00
29 INT174277 Positive_regulation of Positive_regulation of Gopc 23 0.33 8.08 3.73 100.00
30 INT129960 Negative_regulation of Gene_expression of MMP13 19 0.53 7.17 3.55 100.00
31 INT166708 Negative_regulation of Protein_catabolism of Col7a1 2 0.32 2.62 0.92 100.00
32 INT176445 Protein_catabolism of Gopc 23 0.76 7.57 0.75 100.00
33 INT187287 Negative_regulation of Gene_expression of HEY1 2 0.16 2.96 0.45 100.00
34 INT220210 Negative_regulation of Gene_expression of COL10A1 1 0.31 0.51 0.41 100.00
35 INT102890 Localization of ANG 9 0.72 0.41 0.26 100.00
36 INT260174 Gene_expression of Rpe65 29 0.78 4.2 0.19 100.00
37 INT218297 Positive_regulation of Mstn 44 0.68 21.87 0.17 99.96
38 INT207427 Negative_regulation of COL10A1 4 0.36 2.12 0.22 99.96
39 INT295558 Negative_regulation of Positive_regulation of Mstn 2 0.42 1.87 0 99.96
40 INT260779 Negative_regulation of Bmp4 4 0.23 0.94 0 99.96
41 INT953 Positive_regulation of Positive_regulation of GHRH 17 0.67 2.38 8.18 99.96
42 INT4822 Localization of Ca2 417 0.80 99.57 96.45 99.92
43 INT129105 Gene_expression of Mstn 95 0.76 29.96 0.32 99.92
44 INT268496 Regulation of Gene_expression of Mstn 2 0.59 4.41 0 99.92
45 INT85462 Binding of KTWS 3 0.31 2.91 0.54 99.92
46 INT12681 Regulation of Trib3 76 0.53 23.92 26.58 99.92
47 INT295567 Regulation of Negative_regulation of Mstn 5 0.59 1.64 0 99.92
48 INT292414 Regulation of Negative_regulation of Lipg 2 0.09 0.7 0.04 99.92
49 INT90242 Positive_regulation of MYOG 4 0.34 1.46 0.22 99.92
50 INT246755 Regulation of Tsc2 4 0.50 1.01 0 99.92
51 INT351971 Regulation of Stk11 1 0.26 0.43 0 99.92
52 INT123779 Positive_regulation of MMP13 42 0.65 24.3 12.45 99.90
53 INT386 Positive_regulation of Gene_expression of Agt 37 0.70 15.92 8.73 99.90
54 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 99.90
55 INT21686 Positive_regulation of Gene_expression of ras 19 0.42 13.79 4.28 99.90
56 INT61292 Positive_regulation of Gene_expression of Fn1 16 0.35 10.25 0.76 99.90
57 INT90784 Positive_regulation of Gene_expression of Ace2 3 0.40 1.34 0.27 99.90
58 INT247868 Positive_regulation of Narfl 1 0.11 37.11 0.68 99.88
59 INT28671 Positive_regulation of Gene_expression of HLA-E 43 0.67 22.85 8.39 99.88
60 INT309847 Binding of Frl 1 0.02 0.83 0 99.88
61 INT6864 Positive_regulation of Gene_expression of Gfap 110 0.70 59.01 47.07 99.86
62 INT201167 Negative_regulation of Gene_expression of Jph2 1 0.35 2.37 0 99.84
63 INT60165 Positive_regulation of Gene_expression of Ie 7 0.10 3.5 0.37 99.84
64 INT60162 Gene_expression of Ie 41 0.58 23.77 1.52 99.84
65 INT60164 Regulation of Gene_expression of Ie 4 0.08 2.04 0.67 99.84
66 INT322882 Negative_regulation of Mef2c 1 0.28 0.46 0 99.84
67 INT201149 Positive_regulation of Ryr2 7 0.42 5.31 0.29 99.82
68 INT1179 Negative_regulation of Ace 157 0.59 67.03 30.46 99.82
69 INT20552 Negative_regulation of Gene_expression of COL2A1 29 0.56 11.92 4.81 99.80
70 INT32783 Gene_expression of Pah 33 0.60 30.55 6.86 99.80
71 INT1793 Localization of CGA 379 0.81 67.38 114.69 99.80
72 INT201162 Gene_expression of Jph2 1 0.46 4.09 0 99.78
73 INT172370 Binding of MCPH1 6 0.34 4.75 0.13 99.76
74 INT49129 Positive_regulation of GFAP 35 0.69 28.78 10.38 99.76
75 INT81624 Positive_regulation of Gene_expression of Nefm 2 0.40 1.3 0.37 99.76
76 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49 99.74
77 INT15723 Gene_expression of Fn1 47 0.78 37.59 8.51 99.74
78 INT5303 Gene_expression of TAC3 19 0.75 5.25 5.2 99.74
79 INT101474 Positive_regulation of Gene_expression of Gfap 61 0.70 38.3 10.35 99.74
80 INT68394 Gene_expression of KISS1 15 0.73 5.33 2.03 99.74
81 INT101475 Regulation of Gene_expression of Gfap 8 0.62 4.77 1.96 99.74
82 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.72
83 INT166707 Protein_catabolism of Col7a1 24 0.74 20.47 6.39 99.72
84 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99 99.72
85 INT317357 Binding of Prkag1 2 0.25 3.23 0.3 99.72
86 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39 99.72
87 INT25607 Binding of Il1 82 0.47 64.4 23.9 99.72
88 INT43045 Negative_regulation of Regulation of Npr1 3 0.12 0.17 1.65 99.72
89 INT151033 Positive_regulation of Gene_expression of Col10a1 2 0.26 1.06 0.86 99.72
90 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 99.70
91 INT134627 Positive_regulation of Gene_expression of Flt1 9 0.49 7.16 1.12 99.70
92 INT184914 Negative_regulation of Gene_expression of Th 15 0.43 9.17 2.46 99.70
93 INT39758 Gene_expression of Fn1 57 0.65 34.38 6.02 99.70
94 INT60711 Negative_regulation of Binding of Col7a1 4 0.36 2.91 1.04 99.70
95 INT129106 Negative_regulation of Mstn 102 0.57 30.57 0.49 99.68
96 INT134624 Gene_expression of Flt1 77 0.66 48.86 7.27 99.68
97 INT17701 Gene_expression of PTHLH 103 0.78 64.23 8.85 99.68
98 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 99.68
99 INT157690 Negative_regulation of Gene_expression of Fbxo32 4 0.41 1.36 0.4 99.68
100 INT303017 Regulation of Localization of Pah 1 0.29 0.85 0 99.68
101 INT36978 Localization of Pah 9 0.73 7.43 0.82 99.68
102 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2 99.68
103 INT178116 Phosphorylation of GJA1 7 0.80 4.09 0.74 99.68
104 INT255665 Localization of Flt1 5 0.63 7.65 0.51 99.68
105 INT130731 Protein_catabolism of COL2A1 47 0.96 21.86 9.28 99.66
106 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71 99.66
107 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04 99.66
108 INT114499 Gene_expression of MCPH1 38 0.67 26.68 4.55 99.64
109 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86 99.64
110 INT187058 Gene_expression of Ddt 1 0.59 2.34 0 99.64
111 INT117630 Binding of NKG7 1 0.32 1.01 0.07 99.62
112 INT49437 Gene_expression of OAP 25 0.54 20.12 7.34 99.62
113 INT69203 Positive_regulation of Ntf3 43 0.66 19.16 16.49 99.62
114 INT195111 Negative_regulation of Positive_regulation of S100b 1 0.06 1.06 0.18 99.62
115 INT195101 Negative_regulation of Positive_regulation of Gfap 1 0.31 1.02 0.18 99.62
116 INT195077 Negative_regulation of Positive_regulation of Glul 1 0.19 1.06 0.18 99.62
117 INT136304 Negative_regulation of Aqp4 54 0.59 48.42 7.4 99.60
118 INT16089 Gene_expression of Ltc4s 11 0.77 3.37 2.29 99.60
119 INT255107 Negative_regulation of Six5 1 0.37 2.47 0.03 99.60
120 INT226196 Positive_regulation of Gene_expression of Mstn 3 0.54 2.68 0.46 99.60
121 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 99.60
122 INT26678 Negative_regulation of Dmpk 11 0.47 3.45 0.26 99.60
123 INT211585 Negative_regulation of Gene_expression of Dmpk 5 0.47 1.63 0.03 99.60
124 INT255095 Negative_regulation of Gene_expression of Six5 1 0.37 0.85 0 99.60
125 INT80420 Gene_expression of IFI27 145 0.78 63.61 8.83 99.58
126 INT385 Gene_expression of Agt 182 0.78 63.62 37.91 99.58
127 INT5617 Localization of Nppa 266 0.81 83.51 83.89 99.56
128 INT5620 Positive_regulation of Localization of Nppa 105 0.70 30.23 36.45 99.56
129 INT46605 Positive_regulation of NAA50 17 0.49 6.33 1.76 99.56
130 INT149145 Positive_regulation of Gene_expression of Ang2 4 0.34 27.89 0.78 99.56
131 INT162 Regulation of Prl 794 0.62 165.01 322.24 99.56
132 INT113734 Gene_expression of Agrp 31 0.77 11.04 9.02 99.56
133 INT56029 Gene_expression of Nefm 8 0.52 2.83 2.23 99.56
134 INT44147 Positive_regulation of Gene_expression of Agtr2 11 0.50 9.02 1.28 99.56
135 INT293085 Regulation of Rapgef5 1 0.26 0.31 0.09 99.56
136 INT185047 Gene_expression of Pln 8 0.52 1.65 0.29 99.54
137 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 99.54
138 INT43482 Regulation of Binding of ADRB3 4 0.60 1.06 1.54 99.54
139 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12 99.54
140 INT60713 Binding of Col7a1 47 0.43 22.52 6.29 99.54
141 INT151037 Gene_expression of Col10a1 13 0.68 4.47 2.64 99.52
142 INT57187 Positive_regulation of Gfap 49 0.69 27.59 11.46 99.52
143 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05 99.52
144 INT86437 Binding of IL6 154 0.48 121.22 29.3 99.52
145 INT170852 Negative_regulation of Gene_expression of IFI27 16 0.55 8.62 0.05 99.50
146 INT66023 Positive_regulation of Gene_expression of Itgam 25 0.64 12.65 16.56 99.50
147 INT30817 Gene_expression of Th 142 0.76 33.56 38.12 99.50
148 INT1303 Negative_regulation of Npr1 278 0.55 35.1 156.78 99.50
149 INT7017 Regulation of Npr1 45 0.52 3.38 20.05 99.50
150 INT163809 Positive_regulation of Gene_expression of Cd6 2 0.01 0.7 0.92 99.50
151 INT47243 Gene_expression of Prkcg 195 0.78 58.05 108.44 99.48
152 INT151169 Positive_regulation of Gene_expression of Pten 15 0.45 12.88 1.53 99.48
153 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 99.48
154 INT130332 Gene_expression of Adam17 14 0.50 4.84 1.56 99.48
155 INT239215 Binding of Agt 9 0.38 6.75 1.35 99.48
156 INT47994 Negative_regulation of Lipg 45 0.50 27.19 7.24 99.48
157 INT17965 Negative_regulation of Iyd 2 0.07 0.27 0.16 99.48
158 INT65260 Positive_regulation of Col7a1 95 0.69 61.73 18.42 99.48
159 INT27670 Negative_regulation of Ace 122 0.57 79.21 18.08 99.48
160 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 99.46
161 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 99.46
162 INT53393 Positive_regulation of Cyp3a62 25 0.70 7.56 17.69 99.46
163 INT61245 Positive_regulation of Cyp2b2 9 0.64 0.41 4.7 99.46
164 INT289553 Positive_regulation of Gene_expression of Sirt1 21 0.69 20.43 1.03 99.44
165 INT84595 Negative_regulation of Aqp2 11 0.58 4.88 1.78 99.42
166 INT72182 Gene_expression of Mcpt1 167 0.75 123.7 52.15 99.40
167 INT218293 Gene_expression of Acvr2b 14 0.76 4.22 0.44 99.40
168 INT21685 Gene_expression of ras 115 0.66 85.6 7.76 99.40
169 INT81688 Binding of ras 32 0.41 30.13 4.02 99.40
170 INT322888 Negative_regulation of Ihh 1 0.26 0.45 0 99.38
171 INT170601 Positive_regulation of Gene_expression of GOPC 122 0.43 42.79 11.68 99.36
172 INT98310 Regulation of gr 21 0.39 15.04 6.68 99.36
173 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 99.34
174 INT94408 Positive_regulation of Gene_expression of IFI27 28 0.65 12.89 3.53 99.34
175 INT170853 Positive_regulation of Gene_expression of CFD 7 0.23 9.89 1.41 99.34
176 INT128030 Gene_expression of GJA1 23 0.75 7.81 1.88 99.34
177 INT76467 Regulation of Gene_expression of Car2 41 0.37 12.88 4.21 99.34
178 INT21957 Negative_regulation of Negative_regulation of Edn1 5 0.43 1.34 0.69 99.34
179 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 99.32
180 INT105247 Positive_regulation of Gene_expression of Vegfa 12 0.67 12.07 2.05 99.32
181 INT119528 Positive_regulation of Camk2a 135 0.70 26.13 54.7 99.32
182 INT128920 Gene_expression of Runx2 4 0.74 2.6 0.92 99.32
183 INT66025 Gene_expression of Itgam 61 0.78 31.26 26.08 99.30
184 INT80041 Gene_expression of Cd6 8 0.65 3 3.52 99.30
185 INT73945 Gene_expression of Gstp1 8 0.76 2.7 1.66 99.30
186 INT12536 Localization of Prkcg 101 0.80 36.37 73.81 99.28
187 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 99.26
188 INT151168 Gene_expression of Pten 60 0.78 35.63 10.54 99.24
189 INT166021 Positive_regulation of MCL1 36 0.67 62.97 1.44 99.24
190 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19 99.24
191 INT156351 Positive_regulation of Flt1 22 0.51 20.05 0.91 99.24
192 INT6868 Gene_expression of GFAP 136 0.78 84.65 22.7 99.22
193 INT9548 Gene_expression of CHKB 99 0.65 50.86 9.03 99.22
194 INT130729 Negative_regulation of Protein_catabolism of COL2A1 15 0.42 7.59 3.35 99.20
195 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94 99.20
196 INT289575 Gene_expression of Sirt1 47 0.77 29.29 1.47 99.20
197 INT157686 Gene_expression of Fbxo32 14 0.75 8.68 0.9 99.20
198 INT151586 Positive_regulation of Prkag1 51 0.54 18.7 3.34 99.20
199 INT165821 Positive_regulation of Aqp4 27 0.70 24.37 3.22 99.20
200 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 99.20
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