D:Hypochromic Anemia

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Disease Term
Synonyms ANEMIAS HYPOCHROMIC, Chloroses, Chlorosis, Hypochromic Anemias
Documents 37
Hot Single Events 11
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hypochromic Anemia. They are ordered first by their relevance to Hypochromic Anemia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT279265 Binding of MEFV and NLRP3 1 0.07 2.79 0.28 5.00
2 INT279266 CADPS Positive_regulation of Regulation of IL1B 1 0.22 1.43 0.28 5.00
3 INT296372 Binding of IDUA and ACD 1 0.03 2.72 0.23 5.00
4 INT198700 Binding of DSG3 and Pv 1 0.15 1.45 0.18 5.00
5 INT279267 Binding of RIPK2 and Positive_regulation of Gene_expression of CASP1 1 0.26 1.12 0.14 5.00
6 INT315543 NARFL Regulation of Gene_expression of HIF1A 1 0.01 0.63 0 5.00
7 INT315541 ACO1 Negative_regulation of Gene_expression of ALAS2 1 0.17 0.18 0 5.00
8 INT279268 CARD8 Positive_regulation of CASP1 1 0.32 0.3 0 5.00
9 INT315534 Binding of ACO1 and ERN1 1 0.01 0.18 0 5.00
10 INT315535 Binding of ABCB7 and FECH 1 0.28 0.7 0 5.00
11 INT315533 Negative_regulation of GLRX5 Negative_regulation of Gene_expression of ALAS2 1 0.38 1.06 0 5.00
12 INT315532 Binding of NFS1 and ISCU 1 0.19 0.37 0 5.00
13 INT315538 Negative_regulation of GLRX5 Negative_regulation of Gene_expression of SLC40A1 1 0.25 1.14 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hypochromic Anemia. They are ordered first by their pain relevance and then by number of times they were reported in Hypochromic Anemia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43 99.76
2 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 99.40
3 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 99.22
4 INT40215 Negative_regulation of Fech 9 0.57 8.39 1.85 99.20
5 INT1721 Negative_regulation of HP 148 0.42 86.82 16.89 98.40
6 INT17033 Positive_regulation of Trf 21 0.62 11.76 2.68 98.04
7 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54 95.28
8 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 88.08
9 INT45236 Positive_regulation of Gene_expression of Trf 3 0.62 1.67 0.28 86.32
10 INT12194 Gene_expression of Trf 38 0.69 18.1 4.56 85.84
11 INT3323 Gene_expression of ALAS2 10 0.58 7.51 0.21 84.56
12 INT113364 Regulation of NAA50 2 0.44 1.9 0.41 75.00
13 INT20394 Binding of Tbce 12 0.06 5.47 1.78 72.16
14 INT315550 Transcription of GLRX5 1 0.53 0.66 0 69.52
15 INT125586 Gene_expression of Stmn1 13 0.75 8.28 0.42 66.36
16 INT235362 Gene_expression of SNORA73A 8 0.75 4.09 0 66.36
17 INT315562 Gene_expression of GLRX5 1 0.69 4.92 0 61.40
18 INT209501 Gene_expression of CADPS 15 0.65 20.7 2.22 58.04
19 INT220783 Gene_expression of Tert 39 0.77 12.55 1.49 54.20
20 INT315607 Positive_regulation of Gene_expression of GLRX5 1 0.61 2.28 0 48.52
21 INT279349 Localization of IDUA 7 0.76 4.97 0.07 44.08
22 INT315613 Positive_regulation of WNT2 1 0.09 0.41 0 42.72
23 INT315604 Negative_regulation of Positive_regulation of WNT2 1 0.08 0.41 0 42.72
24 INT315553 Positive_regulation of GLRX5 1 0.44 0.68 0 42.48
25 INT162471 Positive_regulation of ERN1 7 0.34 3.02 1.08 40.32
26 INT243267 Positive_regulation of SLC40A1 4 0.41 2.72 0.22 16.56
27 INT243268 Gene_expression of SLC40A1 6 0.60 4.18 0.13 16.04
28 INT315591 Negative_regulation of Positive_regulation of SLC40A1 1 0.25 0.46 0 16.04
29 INT84250 Positive_regulation of IDUA 8 0.56 15.89 0.62 14.00
30 INT315559 Negative_regulation of CIAO1 1 0.19 2.53 0 13.44
31 INT315621 Gene_expression of CIAO1 1 0.34 4.11 0 13.44
32 INT315620 Regulation of Gene_expression of GLRX5 1 0.40 0.5 0 12.00
33 INT296385 Binding of IDUA 12 0.39 20.73 0.93 5.28
34 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
35 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
36 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
37 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
38 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
39 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 5.00
40 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 5.00
41 INT6849 Localization of IL1B 229 0.81 112.56 69.63 5.00
42 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
43 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 5.00
44 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 5.00
45 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 5.00
46 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82 5.00
47 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 5.00
48 INT6484 Binding of IL1B 122 0.47 75.84 35.07 5.00
49 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95 5.00
50 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52 5.00
51 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34 5.00
52 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 5.00
53 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74 5.00
54 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66 5.00
55 INT36262 Positive_regulation of Tbce 35 0.49 28.79 14.33 5.00
56 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 5.00
57 INT8548 Gene_expression of HP 86 0.77 47.62 11.94 5.00
58 INT60500 Negative_regulation of Tbce 21 0.41 13.3 11.1 5.00
59 INT13240 Gene_expression of TF 94 0.76 57.81 10.99 5.00
60 INT71174 Gene_expression of CASP1 44 0.75 30.3 9.37 5.00
61 INT15805 Gene_expression of TFRC 35 0.75 17.44 8.52 5.00
62 INT113987 Localization of IK 29 0.23 16.73 8.25 5.00
63 INT42707 Gene_expression of Tbce 24 0.65 12.92 7.93 5.00
64 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 5.00
65 INT23174 Gene_expression of NLRP3 51 0.72 35.49 6.47 5.00
66 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 5.00
67 INT50050 Gene_expression of CSRP1 23 0.76 16.84 5.86 5.00
68 INT81049 Positive_regulation of CASP1 44 0.67 19.97 5.69 5.00
69 INT41892 Gene_expression of HBM 48 0.64 28.32 5.64 5.00
70 INT12104 Positive_regulation of PLG 45 0.68 28.94 4.81 5.00
71 INT80486 Gene_expression of FECH 13 0.54 10.42 4.8 5.00
72 INT18011 Positive_regulation of HP 60 0.50 31.88 4.75 5.00
73 INT8773 Gene_expression of HBG1 58 0.76 37.6 4.59 5.00
74 INT133630 Negative_regulation of Gene_expression of ESR1 42 0.52 23.89 4.57 5.00
75 INT272273 Gene_expression of NARFL 89 0.54 121.19 4.47 5.00
76 INT46121 Negative_regulation of SERPINH1 14 0.38 10.84 4.41 5.00
77 INT7083 Positive_regulation of HBM 35 0.66 20.96 4.3 5.00
78 INT19190 Regulation of Localization of IL1B 14 0.50 8.71 4.12 5.00
79 INT138872 Gene_expression of SPINK5 21 0.58 30.11 4.12 5.00
80 INT15982 Positive_regulation of NLRP3 25 0.65 23.19 3.57 5.00
81 INT15801 Positive_regulation of TFRC 11 0.33 6.35 3.3 5.00
82 INT32852 Negative_regulation of FECH 18 0.57 10.59 3.08 5.00
83 INT112365 Regulation of HIF1A 27 0.60 21.24 3.05 5.00
84 INT45503 Binding of EPO 42 0.48 24.85 2.88 5.00
85 INT81578 Gene_expression of TRAP 25 0.72 9.75 2.82 5.00
86 INT110210 Negative_regulation of CSRP1 12 0.59 8.96 2.81 5.00
87 INT243496 Positive_regulation of Gene_expression of FECH 4 0.40 4.02 2.34 5.00
88 INT73266 Gene_expression of RB1 50 0.70 29.09 2.31 5.00
89 INT9188 Localization of HBG1 12 0.75 8.14 2.24 5.00
90 INT95592 Positive_regulation of Gene_expression of CASP1 15 0.48 13.06 2.1 5.00
91 INT24453 Binding of NLRP3 18 0.48 13.7 1.93 5.00
92 INT53567 Positive_regulation of FECH 14 0.45 11.03 1.82 5.00
93 INT27762 Positive_regulation of Gene_expression of EPO 18 0.70 17.67 1.45 5.00
94 INT15798 Positive_regulation of Gene_expression of TFRC 9 0.46 4.99 1.42 5.00
95 INT101653 Negative_regulation of SAA1 7 0.39 7 1.33 5.00
96 INT38990 Negative_regulation of IDUA 12 0.59 5.04 1.33 5.00
97 INT162467 Gene_expression of ERN1 10 0.56 5.11 1.26 5.00
98 INT302084 Negative_regulation of WNT2 2 0.09 0.83 1.26 5.00
99 INT38989 Gene_expression of IDUA 22 0.78 16.99 1.26 5.00
100 INT132453 Binding of TF 31 0.36 12.98 1.22 5.00
101 INT34734 Binding of DSG3 4 0.48 2.91 1.17 5.00
102 INT191527 Positive_regulation of Gene_expression of NLRP3 6 0.50 8.65 1.15 5.00
103 INT7207 Regulation of HBG1 27 0.60 22.1 1.12 5.00
104 INT115264 Binding of FECH 9 0.41 7.93 1.1 5.00
105 INT76890 Gene_expression of FGFR2 42 0.65 13.91 1.08 5.00
106 INT15310 Gene_expression of DLEU1 8 0.67 20.57 0.96 5.00
107 INT4436 Gene_expression of ABCB7 7 0.65 9.26 0.93 5.00
108 INT19950 Gene_expression of Abo 13 0.16 4.72 0.84 5.00
109 INT158136 Binding of FGFR2 9 0.26 4.5 0.63 5.00
110 INT94423 Binding of ALAS2 4 0.32 2.1 0.61 5.00
111 INT84826 Negative_regulation of ACD 6 0.50 4.02 0.55 5.00
112 INT140645 Gene_expression of DSG3 6 0.78 4.48 0.52 5.00
113 INT58591 Negative_regulation of Positive_regulation of PLG 4 0.42 2.46 0.51 5.00
114 INT220787 Localization of Tert 5 0.69 0.87 0.49 5.00
115 INT302086 Gene_expression of WNT2 3 0.14 0.97 0.38 5.00
116 INT158764 Binding of SPINK5 7 0.35 8.84 0.37 5.00
117 INT247999 Negative_regulation of FXYD1 2 0.06 1.75 0.35 5.00
118 INT3321 Positive_regulation of ALAS2 10 0.51 3.08 0.32 5.00
119 INT220770 Binding of Tert 7 0.37 1.09 0.27 5.00
120 INT166958 Gene_expression of LYRM4 4 0.18 2.9 0.27 5.00
121 INT220785 Positive_regulation of Tert 15 0.68 6.9 0.25 5.00
122 INT221496 Localization of ISCA1 4 0.73 2.12 0.23 5.00
123 INT236278 Negative_regulation of CADPS 4 0.36 2.16 0.22 5.00
124 INT241863 Binding of SLC40A1 4 0.28 3.86 0.22 5.00
125 INT84244 Positive_regulation of Gene_expression of IDUA 5 0.70 3.75 0.19 5.00
126 INT236980 Gene_expression of ISCA1 9 0.53 2.43 0.19 5.00
127 INT201691 Binding of RIPK2 2 0.18 1.51 0.17 5.00
128 INT170629 Negative_regulation of Gene_expression of ABCB7 2 0.37 1.32 0.17 5.00
129 INT134952 Localization of DSG3 3 0.81 3.23 0.16 5.00
130 INT198697 Negative_regulation of Pv 1 0.12 0.87 0.13 5.00
131 INT247998 Negative_regulation of SNORA73A 2 0.41 0.85 0.12 5.00
132 INT315643 Negative_regulation of Gene_expression of FECH 1 0.29 0.71 0.1 5.00
133 INT131139 Binding of ACO1 3 0.27 1.81 0.1 5.00
134 INT95756 Gene_expression of ACO1 3 0.27 2.49 0.1 5.00
135 INT125587 Positive_regulation of Gene_expression of Stmn1 9 0.67 4.2 0.08 5.00
136 INT296382 Positive_regulation of SLC11A2 3 0.31 1.49 0.08 5.00
137 INT174848 Gene_expression of ISCU 2 0.59 2.79 0.08 5.00
138 INT315554 Localization of NFS1 1 0.43 0.28 0.07 5.00
139 INT315622 Protein_catabolism of FECH 1 0.77 0.49 0.07 5.00
140 INT315598 Localization of FXN 1 0.43 1.04 0.07 5.00
141 INT315626 Localization of DLEU1 2 0.35 4.17 0.07 5.00
142 INT187992 Binding of CADPS 2 0.31 2.05 0.06 5.00
143 INT162956 Binding of ACD 3 0.32 3.04 0.05 5.00
144 INT315630 Gene_expression of FXN 8 0.64 20.05 0.05 5.00
145 INT315624 Positive_regulation of Gene_expression of ISCU 1 0.38 0.23 0.03 5.00
146 INT296384 Regulation of SLC40A1 2 0.01 0.83 0.03 5.00
147 INT315583 Positive_regulation of Binding of NFS1 1 0.25 0 0 5.00
148 INT315551 Negative_regulation of Gene_expression of ALAS2 1 0.37 1.11 0 5.00
149 INT296386 Localization of DEFA6 3 0.05 0.88 0 5.00
150 INT315585 Localization of SLC25A37 1 0.13 0.47 0 5.00
151 INT315581 Positive_regulation of Phosphorylation of ISCU 1 0.44 0.33 0 5.00
152 INT315617 Positive_regulation of Gene_expression of SLC25A37 1 0.10 0.39 0 5.00
153 INT315565 Negative_regulation of Gene_expression of SLC40A1 1 0.25 1.73 0 5.00
154 INT186639 Gene_expression of SLC11A2 4 0.65 1.91 0 5.00
155 INT315631 Protein_catabolism of IREB2 1 0.44 0.4 0 5.00
156 INT315614 Negative_regulation of Transcription of FXN 1 0.25 0.82 0 5.00
157 INT247997 Regulation of FXYD1 1 0.00 0.51 0 5.00
158 INT315602 Binding of ISCA1 1 0.30 0 0 5.00
159 INT198699 Gene_expression of TCF15 2 0.75 0.43 0 5.00
160 INT315587 Positive_regulation of Gene_expression of CIAO1 1 0.22 1.6 0 5.00
161 INT248001 Positive_regulation of Gene_expression of SNORA73A 1 0.49 2.51 0 5.00
162 INT315575 Transcription of SLC40A1 1 0.40 0.85 0 5.00
163 INT315637 Transcription of FXN 1 0.40 1.44 0 5.00
164 INT315563 Positive_regulation of Gene_expression of FXN 4 0.41 5.05 0 5.00
165 INT315634 Negative_regulation of Binding of ISCU 1 0.33 0.28 0 5.00
166 INT315597 Negative_regulation of ISCU 1 0.51 0.22 0 5.00
167 INT315600 Regulation of CIAO1 1 0.20 0.39 0 5.00
168 INT247976 Negative_regulation of Alm 2 0.04 0.66 0 5.00
169 INT315571 Binding of NFS1 1 0.19 0 0 5.00
170 INT315627 Binding of GLRX5 1 0.33 0 0 5.00
171 INT315606 Regulation of Gene_expression of WNT2 1 0.08 0.84 0 5.00
172 INT315644 Negative_regulation of Transcription of DLEU1 1 0.21 0.64 0 5.00
173 INT315555 Binding of FXN 1 0.28 1.29 0 5.00
174 INT315605 Binding of ABCB7 1 0.33 1.84 0 5.00
175 INT315592 Positive_regulation of Gene_expression of SLC40A1 1 0.41 3.52 0 5.00
176 INT315640 Gene_expression of NUBP1 1 0.41 0.32 0 5.00
177 INT315567 Positive_regulation of Negative_regulation of CIAO1 1 0.22 1.29 0 5.00
178 INT315556 Positive_regulation of Binding of ALAS2 1 0.43 1.05 0 5.00
179 INT315623 Positive_regulation of Localization of ACO1 1 0.20 0.79 0 5.00
180 INT315635 Positive_regulation of FXN 2 0.41 5.76 0 5.00
181 INT315608 Localization of NFU1 1 0.14 0 0 5.00
182 INT252722 Binding of IREB2 2 0.16 1.31 0 5.00
183 INT315596 Localization of ISCA2 1 0.11 0 0 5.00
184 INT279271 Positive_regulation of CARD8 1 0.33 0.3 0 5.00
185 INT315601 Positive_regulation of NFU1 1 0.22 0.13 0 5.00
186 INT315642 Negative_regulation of Gene_expression of NFU1 1 0.16 0.37 0 5.00
187 INT315636 Negative_regulation of ABCB7 1 0.38 0.17 0 5.00
188 INT315588 Regulation of ACO1 1 0.18 0.57 0 5.00
189 INT315570 Negative_regulation of Positive_regulation of TFRC 1 0.19 0.08 0 5.00
190 INT315573 Negative_regulation of Gene_expression of NFS1 1 0.24 0.74 0 5.00
191 INT315568 Regulation of Gene_expression of CIAO1 1 0.20 0.15 0 5.00
192 INT355896 Regulation of NCBP2 1 0.01 1.76 0 5.00
193 INT174850 Binding of ISCU 2 0.33 0.51 0 5.00
194 INT248000 Positive_regulation of Gene_expression of TRAP 1 0.05 0 0 5.00
195 INT315638 Gene_expression of GLRX3 1 0.25 0 0 5.00
196 INT296383 Regulation of SLC11A2 1 0.07 0.33 0 5.00
197 INT315564 Binding of NFU1 1 0.16 0 0 5.00
198 INT247975 Gene_expression of Alm 2 0.07 1.31 0 5.00
199 INT315619 Regulation of Gene_expression of NFS1 1 0.26 0.74 0 5.00
200 INT315593 Regulation of Transcription of SLC40A1 1 0.26 1.7 0 5.00
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