D:Hypohidrosis

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Anhidrosis
Documents 179
Hot Single Events 37
Hot Interactions 4

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hypohidrosis. They are ordered first by their relevance to Hypohidrosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT122927 Ntrk1 Positive_regulation of SPTLC1 1 0.00 0.65 0.09 92.76
2 INT98908 Binding of NTRK1 and PKLR 1 0.41 1.95 1.18 92.04
3 INT98906 Positive_regulation of Binding of NTRK1 and PKLR 1 0.56 1.95 1.18 92.04
4 INT118980 NTRK1 Positive_regulation of NGF 1 0.56 1.45 1.39 86.08
5 INT118979 NGF Positive_regulation of Phosphorylation of NTRK1 1 0.56 0.67 0.67 75.92
6 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92 75.00
7 INT279242 Negative_regulation of Binding of GLA and SH3GL3 1 0.08 1.22 0 72.24
8 INT279240 Binding of GLA and SH3GL3 1 0.07 1.21 0 72.24
9 INT244328 ELF3 Negative_regulation of Positive_regulation of SH3GL3 3 0.20 1.26 0.04 35.36
10 INT244329 ELF3 Positive_regulation of Gene_expression of SH3GL3 1 0.27 0.66 0 30.16
11 INT110835 Binding of SPTLC2 and SPTLC1 2 0.42 1.36 0.68 5.00
12 INT110834 Binding of AGXT and SPTLC2 2 0.27 0.71 0.36 5.00
13 INT229785 Binding of RAB7A and SPTLC1 1 0.40 1.5 0.27 5.00
14 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19 5.00
15 INT153620 Binding of Ntrk1 and WNK1 1 0.02 0.85 0.12 5.00
16 INT352175 USE1 Regulation of NAGA 1 0.01 0.33 0 5.00
17 INT279241 Binding of ELF3 and GLA 1 0.20 0.53 0 5.00
18 INT256632 Binding of PTCH1 and Jkamp 1 0.00 2.32 0 5.00
19 INT279239 ELF3 Regulation of SH3GL3 1 0.11 0.44 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hypohidrosis. They are ordered first by their pain relevance and then by number of times they were reported in Hypohidrosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT229788 Negative_regulation of SPTLC1 1 0.38 4.82 3.53 100.00
2 INT71151 Regulation of NTRK1 10 0.62 6.65 6.21 99.36
3 INT3550 Negative_regulation of GLA 52 0.59 33.93 5.26 99.24
4 INT158326 Phosphorylation of Tie1 1 0.16 0.8 0.45 96.76
5 INT63769 Regulation of Ngf 44 0.62 21.82 25.84 96.44
6 INT78981 Regulation of Ntrk1 6 0.44 3.89 4.52 96.44
7 INT81750 Regulation of Ntrk1 13 0.52 6.03 4.37 96.44
8 INT23435 Positive_regulation of NGF 54 0.70 32.41 30.11 96.32
9 INT62610 Phosphorylation of Ntrk1 5 0.56 1.64 2.68 95.44
10 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33 95.04
11 INT129020 Phosphorylation of Ntrk1 17 0.80 5.97 6.37 94.48
12 INT93110 Regulation of CDCP1 16 0.03 7.98 3.83 94.40
13 INT210060 Localization of SH3GL3 4 0.59 6.61 1.37 94.00
14 INT48313 Binding of NTRK1 19 0.47 14.44 6.12 93.20
15 INT93111 Phosphorylation of NGF 1 0.49 0.61 0.73 92.92
16 INT28325 Negative_regulation of Tst 13 0.51 12.41 3.16 92.88
17 INT85048 Regulation of NGF 19 0.62 11.61 10.5 92.80
18 INT126675 Negative_regulation of NAT8 2 0.42 1.95 0.33 91.56
19 INT62373 Negative_regulation of NGF 34 0.59 25.87 22.38 91.32
20 INT20216 Localization of NGF 40 0.80 18.16 16.61 91.32
21 INT93109 Phosphorylation of NTRK1 5 0.80 3.22 2.99 90.56
22 INT66041 Positive_regulation of NTRK1 24 0.70 16.12 8.42 89.92
23 INT210058 Regulation of ELF3 11 0.29 7.93 2.51 89.24
24 INT71152 Negative_regulation of NTRK1 15 0.59 10.28 5.5 87.20
25 INT85047 Positive_regulation of Negative_regulation of NTRK1 3 0.47 2.13 1.3 87.20
26 INT223091 Gene_expression of ELF3 45 0.62 17.9 1.56 87.04
27 INT16385 Regulation of C3 20 0.41 9.98 1.92 85.12
28 INT352186 Negative_regulation of Gene_expression of A4GALT 1 0.20 2.56 1.06 85.04
29 INT142724 Negative_regulation of A4GALT 11 0.53 8.23 2.61 85.04
30 INT167153 Gene_expression of A4GALT 10 0.49 10.45 1.71 84.00
31 INT81955 Positive_regulation of SPTLC1 12 0.70 10.25 3.12 83.72
32 INT103767 Phosphorylation of DDR1 6 0.20 4.67 1.56 83.48
33 INT103766 Positive_regulation of Phosphorylation of DDR1 2 0.13 1.94 1.19 83.48
34 INT85049 Negative_regulation of Positive_regulation of NTRK1 1 0.59 0.56 0.64 82.76
35 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83 82.16
36 INT210064 Negative_regulation of Localization of SH3GL3 3 0.31 1.44 0.54 80.64
37 INT48312 Gene_expression of NTRK1 72 0.78 38.21 22.24 80.48
38 INT57562 Gene_expression of GLA 52 0.77 24.62 6.14 79.56
39 INT23638 Negative_regulation of GAL 17 0.42 5.68 5.04 78.24
40 INT91100 Binding of SPTLC1 10 0.47 12.85 5.71 77.84
41 INT164683 Negative_regulation of Gene_expression of PKP1 1 0.59 1.5 0.17 77.52
42 INT164682 Gene_expression of PKP1 3 0.78 3.04 0.17 77.52
43 INT118981 Positive_regulation of Phosphorylation of NTRK1 1 0.49 0.66 0.66 75.08
44 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 75.00
45 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 75.00
46 INT46221 Positive_regulation of Gene_expression of IgG 46 0.53 33.66 7.7 75.00
47 INT44717 Gene_expression of TNFSF14 12 0.75 13.44 3.72 75.00
48 INT129848 Negative_regulation of CD5 3 0.42 3.01 0.67 75.00
49 INT85046 Positive_regulation of Positive_regulation of NTRK1 2 0.50 0.63 1.51 72.92
50 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45 71.32
51 INT21952 Gene_expression of GDNF 42 0.78 20.32 9.62 71.00
52 INT88006 Positive_regulation of GDNF 5 0.45 2.55 2.14 71.00
53 INT210057 Gene_expression of SH3GL3 24 0.50 8.69 0.94 70.88
54 INT145884 Negative_regulation of SH3GL3 19 0.43 12.67 1.72 70.76
55 INT99970 Regulation of Binding of NGF 2 0.27 2.35 1.93 70.72
56 INT71150 Binding of NGF 22 0.46 13.67 14.81 70.24
57 INT16131 Negative_regulation of GBE1 37 0.30 10.32 8.15 70.24
58 INT131835 Positive_regulation of Wnk1 1 0.07 1.28 0.07 69.72
59 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12 68.60
60 INT101239 Gene_expression of NTF3 9 0.76 5.91 2.97 68.60
61 INT68829 Binding of ELF3 14 0.47 7.96 2 66.72
62 INT210065 Positive_regulation of SH3GL3 8 0.45 6.45 0.96 58.36
63 INT164680 Negative_regulation of PKP1 1 0.43 0.38 0.07 56.16
64 INT164685 Negative_regulation of PKP2 1 0.35 0.38 0.07 56.16
65 INT164681 Transcription of PKP2 1 0.57 0.38 0.07 55.04
66 INT164684 Transcription of PKP1 1 0.69 0.75 0.13 54.00
67 INT60286 Gene_expression of PKLR 5 0.65 2.14 1.04 50.84
68 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 50.00
69 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 50.00
70 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 50.00
71 INT107294 Positive_regulation of Cdt1 3 0.24 1.52 0.43 48.68
72 INT63373 Negative_regulation of Gene_expression of NGF 14 0.57 8.9 7.1 46.16
73 INT121513 Positive_regulation of A4GALT 21 0.63 16.06 1.59 45.04
74 INT244330 Localization of ELF3 8 0.56 2.71 0.18 42.92
75 INT127459 Negative_regulation of PAH 18 0.56 15.15 1.05 40.88
76 INT22834 Negative_regulation of CYP21A2 28 0.58 23.07 7.13 40.48
77 INT210063 Negative_regulation of Positive_regulation of SH3GL3 4 0.28 1.84 0.31 35.36
78 INT210072 Negative_regulation of Gene_expression of SH3GL3 13 0.31 2.94 0.47 30.16
79 INT183207 Negative_regulation of USE1 14 0.18 10.97 4 23.84
80 INT36179 Regulation of GLA 11 0.44 6.56 1.12 23.60
81 INT80338 Gene_expression of SPTLC1 10 0.78 4.06 1.09 23.00
82 INT229792 Negative_regulation of Positive_regulation of RAB7A 1 0.40 1.49 1.17 20.56
83 INT229793 Negative_regulation of Positive_regulation of SPTLC1 1 0.43 1.49 1.17 20.56
84 INT210073 Regulation of Negative_regulation of SH3GL3 2 0.20 1.24 0.35 20.04
85 INT229794 Positive_regulation of RAB7A 2 0.65 11.68 1.31 19.52
86 INT210061 Regulation of SH3GL3 6 0.20 1.81 0.5 19.20
87 INT352180 Negative_regulation of Gene_expression of GLA 1 0.42 1.06 0.13 14.64
88 INT65545 Localization of EGFR 35 0.79 20.8 1.88 13.04
89 INT57560 Positive_regulation of GLA 14 0.54 5.01 0.83 7.84
90 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 5.00
91 INT738 Regulation of POMC 459 0.62 111.19 243.74 5.00
92 INT6354 Localization of Gabrg1 321 0.74 41.41 186.74 5.00
93 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 5.00
94 INT695 Binding of POMC 304 0.48 56.66 126.85 5.00
95 INT6323 Positive_regulation of Gabrg1 213 0.70 45.08 124.34 5.00
96 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
97 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32 5.00
98 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 5.00
99 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
100 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28 5.00
101 INT51163 Gene_expression of Gal 119 0.78 67.48 49.23 5.00
102 INT654 Localization of REN 250 0.81 75.12 47.86 5.00
103 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49 5.00
104 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 5.00
105 INT6357 Positive_regulation of Localization of Gabrg1 53 0.41 7.03 39.21 5.00
106 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 5.00
107 INT80690 Positive_regulation of MAPK8 223 0.68 125.63 36.75 5.00
108 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 5.00
109 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99 5.00
110 INT33327 Positive_regulation of Gene_expression of Gabrg1 39 0.69 9.68 18.82 5.00
111 INT14306 Positive_regulation of Gal 36 0.70 21.66 18.51 5.00
112 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 5.00
113 INT6947 Negative_regulation of Gene_expression of POMC 37 0.59 10.32 14.14 5.00
114 INT18773 Localization of ALB 117 0.80 69.18 13.8 5.00
115 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 5.00
116 INT11288 Negative_regulation of CRH 44 0.00 16.69 12.37 5.00
117 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55 5.00
118 INT10009 Positive_regulation of TRH 31 0.67 8.94 11.03 5.00
119 INT48978 Negative_regulation of FOS 41 0.57 11.94 9.14 5.00
120 INT27551 Gene_expression of SERPINH1 45 0.62 42.87 9.04 5.00
121 INT51165 Binding of Gal 10 0.48 2.56 8.41 5.00
122 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29 5.00
123 INT56223 Positive_regulation of MPO 35 0.70 43 8.2 5.00
124 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9 5.00
125 INT107386 Negative_regulation of AGTR1 37 0.55 35.94 5.15 5.00
126 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 5.00
127 INT57274 Positive_regulation of Gene_expression of COL7A1 50 0.69 24.19 4.72 5.00
128 INT4679 Negative_regulation of RAPGEF5 55 0.57 47.51 4.55 5.00
129 INT26477 Regulation of ACE 26 0.45 16.31 4.33 5.00
130 INT5219 Negative_regulation of DBP 43 0.57 23.35 4.26 5.00
131 INT57273 Positive_regulation of Gene_expression of FN1 26 0.47 17.83 4.2 5.00
132 INT83411 Binding of Ntrk1 6 0.19 3.7 3.74 5.00
133 INT16723 Regulation of GBE1 16 0.11 4.3 3.7 5.00
134 INT163832 Negative_regulation of Gene_expression of EGFR 50 0.59 39.71 3.45 5.00
135 INT117348 Regulation of EGFR 75 0.61 47.73 3.09 5.00
136 INT133144 Localization of Mtpn 18 0.24 7.88 2.77 5.00
137 INT143841 Positive_regulation of Mtpn 17 0.17 5.46 2.68 5.00
138 INT96693 Binding of COL2A1 45 0.46 37.11 2.61 5.00
139 INT150476 Positive_regulation of ELF3 32 0.56 13.61 2.39 5.00
140 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77 5.00
141 INT72870 Negative_regulation of SPTLC2 7 0.57 1.82 1.73 5.00
142 INT139077 Negative_regulation of Ptch1 5 0.56 5.22 1.29 5.00
143 INT110838 Regulation of AGXT 5 0.46 2.21 1.28 5.00
144 INT229791 Gene_expression of RAB7A 2 0.73 6.48 1.21 5.00
145 INT86670 Negative_regulation of AGXT 6 0.57 2.24 1.18 5.00
146 INT77246 Positive_regulation of WNK1 5 0.10 4.24 1.13 5.00
147 INT210392 Regulation of PDGFA 10 0.36 11.41 1.12 5.00
148 INT66043 Regulation of SPTLC2 3 0.44 1.62 1.09 5.00
149 INT229787 Gene_expression of AGXT 4 0.16 0.94 1.08 5.00
150 INT188774 Binding of RAPGEF5 12 0.29 13.55 1.04 5.00
151 INT4681 Localization of RAPGEF5 12 0.68 8.69 0.93 5.00
152 INT188317 Positive_regulation of Gene_expression of PDGFA 15 0.46 12.7 0.91 5.00
153 INT135299 Binding of PTCH1 10 0.48 12.16 0.84 5.00
154 INT116763 Gene_expression of IKBKAP 63 0.78 54.53 0.79 5.00
155 INT142416 Binding of Ptch1 6 0.34 4.92 0.74 5.00
156 INT229789 Regulation of RAB7A 4 0.42 7.09 0.72 5.00
157 INT229786 Transcription of SPTLC1 1 0.60 0.78 0.71 5.00
158 INT259902 Regulation of Gene_expression of ACE 3 0.45 1.87 0.7 5.00
159 INT153257 Regulation of Ptch1 6 0.36 5.92 0.67 5.00
160 INT66042 Positive_regulation of SPTLC2 2 0.68 0.97 0.66 5.00
161 INT164258 Positive_regulation of Gene_expression of GLA 6 0.47 0.55 0.65 5.00
162 INT208522 Gene_expression of SCGB1A1 7 0.65 3.2 0.58 5.00
163 INT121514 Localization of A4GALT 7 0.25 4.77 0.58 5.00
164 INT65919 Gene_expression of Ptch1 11 0.75 6.47 0.56 5.00
165 INT37351 Negative_regulation of IKBKAP 16 0.58 9.6 0.56 5.00
166 INT16671 Gene_expression of MBTPS1 7 0.30 4.8 0.52 5.00
167 INT155290 Negative_regulation of Negative_regulation of GBE1 2 0.03 1 0.48 5.00
168 INT11118 Gene_expression of RAPGEF5 13 0.65 9.35 0.43 5.00
169 INT217067 Regulation of Positive_regulation of MAPK8 7 0.45 3.09 0.43 5.00
170 INT256628 Regulation of Nsdhl 2 0.11 4.12 0.43 5.00
171 INT94146 Regulation of SPTLC1 2 0.51 2.39 0.36 5.00
172 INT110837 Binding of SPTLC2 1 0.36 0.7 0.35 5.00
173 INT66193 Negative_regulation of Btd 3 0.59 3.39 0.32 5.00
174 INT183055 Gene_expression of PTCH1 10 0.77 15.54 0.26 5.00
175 INT263255 Negative_regulation of Negative_regulation of AGTR1 2 0.30 2.88 0.25 5.00
176 INT229790 Regulation of Gene_expression of AGXT 1 0.11 0.47 0.24 5.00
177 INT117050 Binding of GLA 8 0.47 2.41 0.22 5.00
178 INT251821 Negative_regulation of COL11A1 3 0.42 3.45 0.16 5.00
179 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16 5.00
180 INT245116 Regulation of Gene_expression of ELF3 3 0.41 1.36 0.14 5.00
181 INT279245 Regulation of Regulation of SH3GL3 1 0.11 0.59 0.11 5.00
182 INT279248 Binding of SH3GL3 1 0.09 0.19 0.08 5.00
183 INT213515 Binding of Shh 8 0.37 1.92 0.08 5.00
184 INT279250 Regulation of Localization of SH3GL3 1 0.12 0.42 0.07 5.00
185 INT205973 Binding of SHH 3 0.35 1.03 0.07 5.00
186 INT245115 Positive_regulation of Gene_expression of ELF3 8 0.40 2.23 0.06 5.00
187 INT352176 Localization of Cst3 1 0.78 1.71 0.04 5.00
188 INT234263 Negative_regulation of ELF3 6 0.39 3.9 0.04 5.00
189 INT352188 Negative_regulation of Localization of A4GALT 1 0.17 0 0 5.00
190 INT352187 Phosphorylation of A4GALT 1 0.27 0.13 0 5.00
191 INT279247 Positive_regulation of Localization of SH3GL3 1 0.14 0 0 5.00
192 INT352181 Regulation of NAGA 1 0.11 0.34 0 5.00
193 INT256625 Negative_regulation of Ptch2 1 0.42 1.27 0 5.00
194 INT256627 Regulation of Negative_regulation of Ptch2 1 0.32 1.33 0 5.00
195 INT279251 Localization of SCGB1A1 1 0.73 1.07 0 5.00
196 INT256626 Regulation of Ptch2 1 0.28 1.11 0 5.00
197 INT352185 Negative_regulation of PCDH11X 1 0.01 0.83 0 5.00
198 INT352182 Regulation of A4GALT 1 0.15 0.18 0 5.00
199 INT279246 Positive_regulation of Gene_expression of SH3GL3 1 0.12 0.59 0 5.00
200 INT256631 Positive_regulation of PTCH1 2 0.13 1.97 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox