D:Hypolipidemia

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Disease Term
Synonyms Abetalipoproteinaemia, Abetalipoproteinemia, Acanthocytosis, BASSEN KORNZWEIG SYNDROME, Familial A Lipoprotein Deficiency, Familial Alpha Lipoprotein Deficiency, HEREDITARY A LIPOPROTEIN DEFICIENCY, HEREDITARY ALPHA LIPOPROTEIN DEFICIENCY, Hypoalphalipoproteinaemia, Hypoalphalipoproteinemia, Hypobetalipoproteinaemia
Documents 163
Hot Single Events 85
Hot Interactions 4

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hypolipidemia. They are ordered first by their relevance to Hypolipidemia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT95125 Binding of KCNA6 and SGCG 1 0.40 2.73 0.18 100.00
2 INT230423 INS Negative_regulation of Lipg 1 0.03 0.74 0.03 98.28
3 INT239341 Binding of Abca1 and Hdl1 1 0.04 4.78 0 92.64
4 INT300199 PCSK9 Regulation of Gene_expression of LDLR 1 0.13 0.88 0 83.44
5 INT190885 Binding of Apoa2 and Hdl1 1 0.02 0.73 0.07 70.56
6 INT239321 Binding of Abca1 and Apoa1 1 0.11 1.61 0 68.68
7 INT290194 Binding of PLTP and Hdl1 1 0.07 7.3 0.13 63.60
8 INT239406 Binding of MTTP and TAOK1 1 0.02 0.51 0 55.48
9 INT239408 Binding of PADI1 and TAOK1 1 0.01 0.51 0 55.48
10 INT239407 Binding of MTTP and PADI1 1 0.23 0.5 0 54.28
11 INT239348 Binding of Apoa1 and Hdl1 1 0.03 3.34 0.05 53.12
12 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11 50.00
13 INT307215 Negative_regulation of Prkca Negative_regulation of Ppara 1 0.09 0.21 0.3 50.00
14 INT307207 Ppara Positive_regulation of Apoa2 1 0.10 0.94 0.25 50.00
15 INT307217 Fas Positive_regulation of Agpat2 1 0.06 0.27 0.07 50.00
16 INT307218 Binding of Rxra and D0Nrs1 1 0.00 0.1 0.05 50.00
17 INT307209 Fas Positive_regulation of Fasn 1 0.05 0.13 0.03 50.00
18 INT307214 Hnf4a Regulation of Ppara 1 0.18 0.35 0 50.00
19 INT307213 Srebf1 Regulation of Gene_expression of Fasn 1 0.05 0.06 0 50.00
20 INT307219 Mlxipl Regulation of Srebf1 1 0.07 0.12 0 50.00
21 INT307210 Ide Positive_regulation of Ppara 1 0.02 0.18 0 50.00
22 INT307216 Ppara Regulation of Srebf1 1 0.22 0.12 0 50.00
23 INT307208 Binding of Ppara and Nrip1 1 0.34 0.31 0 50.00
24 INT307212 Ide Regulation of Lep 1 0.00 0.51 0 50.00
25 INT239337 Abca1 Positive_regulation of RCT 1 0.07 3.11 0.24 40.12
26 INT239333 Abcg1 Positive_regulation of RCT 1 0.06 1.29 0.03 39.72
27 INT239322 Hdl1 Positive_regulation of RCT 1 0.02 2.16 0.03 37.76
28 INT239340 Cand1 Positive_regulation of RCT 1 0.11 1.26 0.03 37.60
29 INT100783 Binding of CYP2B6 and CYP3A4 2 0.17 2 0.77 5.00
30 INT213026 Hdl1 Positive_regulation of Nos3 5 0.16 7.92 0.73 5.00
31 INT344709 Niacr1 Positive_regulation of Hdl1 1 0.32 2.74 0.46 5.00
32 INT213027 Binding of Apoa1 and Scarb1 6 0.09 7.52 0.43 5.00
33 INT301665 CYP2C9 Regulation of Binding of Ppara 1 0.26 1.79 0.34 5.00
34 INT239344 Nr1h2 Positive_regulation of Gene_expression of Srebf1 1 0.26 0.84 0.29 5.00
35 INT239324 Nr1h2 Positive_regulation of Hltf 1 0.04 0.78 0.29 5.00
36 INT239347 Nr1h2 Positive_regulation of Srebf1 1 0.26 0.78 0.29 5.00
37 INT239329 Nr1h2 Positive_regulation of Gene_expression of Hltf 1 0.04 0.84 0.29 5.00
38 INT239336 Nr1h2 Positive_regulation of Gene_expression of Fas 1 0.07 0.84 0.29 5.00
39 INT344704 Positive_regulation of Ppara Positive_regulation of Binding of Hdl1 1 0.13 0.83 0.28 5.00
40 INT301666 Binding of CYP4F2 and Ltb4r1 1 0.02 0.57 0.28 5.00
41 INT344715 Positive_regulation of Ppara Positive_regulation of Gene_expression of Pltp 1 0.02 0.83 0.28 5.00
42 INT301668 Ltb4r1 Positive_regulation of Gene_expression of IL8 1 0.00 0.9 0.27 5.00
43 INT301671 Ltc4s Positive_regulation of Gene_expression of IL8 1 0.00 0.9 0.27 5.00
44 INT301670 Binding of CYP4F2 and Cyp4f18 1 0.02 1.04 0.27 5.00
45 INT239335 Eef1a2 Positive_regulation of Ppara 1 0.27 0.57 0.26 5.00
46 INT344714 Nr1h4 Negative_regulation of Gene_expression of Lipg 1 0.02 0.77 0.23 5.00
47 INT173120 Binding of PPARA and NR1H4 8 0.09 2.79 0.23 5.00
48 INT189321 Binding of Apoa1 and Hdlcl1 1 0.00 0.68 0.2 5.00
49 INT239328 Hdl1 Regulation of Gene_expression of Kitl 1 0.08 1.86 0.2 5.00
50 INT301615 Binding of Cyp2e1 and Samsn1 1 0.02 2.42 0.18 5.00
51 INT300193 Binding of APOA1 and INSL4 1 0.01 2.17 0.18 5.00
52 INT239316 Nr1h2 Positive_regulation of Transcription of Abca1 1 0.15 0.67 0.18 5.00
53 INT198700 Binding of DSG3 and Pv 1 0.15 1.45 0.18 5.00
54 INT344721 Binding of AHA and Hdl1 1 0.02 1.16 0.15 5.00
55 INT213005 Hdl1 Positive_regulation of Akt1 3 0.19 3.81 0.14 5.00
56 INT344707 Scarb1 Positive_regulation of Positive_regulation of Hdl1 1 0.14 0.88 0.14 5.00
57 INT239323 Binding of Nr1h2 and Positive_regulation of Positive_regulation of Tgfb1 1 0.00 3.71 0.14 5.00
58 INT344710 Lipc Positive_regulation of Positive_regulation of Hdl1 1 0.04 0.87 0.14 5.00
59 INT239317 Egfl7 Positive_regulation of Hdl1 2 0.01 2.3 0.14 5.00
60 INT239355 Binding of Nr1h2 and Positive_regulation of Gene_expression of CETP 1 0.17 3.75 0.14 5.00
61 INT301638 Ppara Regulation of Slc27a2 1 0.30 0.29 0.14 5.00
62 INT239339 Hdl1 Negative_regulation of Gene_expression of Paf 1 0.02 1.43 0.13 5.00
63 INT173200 PPA1 Positive_regulation of Myc 1 0.08 0.5 0.12 5.00
64 INT344705 Nr1h2 Regulation of Scarb1 1 0.04 1.53 0.12 5.00
65 INT344706 Nr1h2 Regulation of Abca1 1 0.03 2.39 0.12 5.00
66 INT173121 PPARA Negative_regulation of Gene_expression of CYP7A1 1 0.18 0.48 0.12 5.00
67 INT173129 PTGS2 Regulation of IER3 1 0.01 0.36 0.12 5.00
68 INT344713 Nr1h2 Regulation of Abcg1 1 0.03 2.39 0.12 5.00
69 INT173122 PPA1 Positive_regulation of HRAS 1 0.08 0.5 0.12 5.00
70 INT182886 Ros1 Positive_regulation of Mapk8 3 0.09 2.3 0.12 5.00
71 INT173125 PPA1 Positive_regulation of JUN 1 0.06 0.5 0.12 5.00
72 INT173119 PPA1 Regulation of IER3 1 0.00 0.36 0.12 5.00
73 INT301637 Positive_regulation of Ros1 Positive_regulation of Phosphorylation of Ins1 1 0.00 0.91 0.1 5.00
74 INT173126 CYP8B1 Positive_regulation of PPARA 1 0.25 0.39 0.1 5.00
75 INT240903 Mapk8 Positive_regulation of Ros1 2 0.09 1.01 0.1 5.00
76 INT173124 PPA1 Regulation of ZFP37 1 0.00 0.44 0.1 5.00
77 INT301660 Ppara Regulation of Gene_expression of CYP4A11 1 0.24 0.65 0.09 5.00
78 INT199667 Cep290 Regulation of Atf4 1 0.04 1.96 0.09 5.00
79 INT301663 Ppara Regulation of CYP4A11 1 0.14 0.65 0.09 5.00
80 INT199666 Cntln Regulation of Atf4 1 0.00 1.95 0.09 5.00
81 INT301655 Irs1 Negative_regulation of Transcription of Pck1 1 0.03 0.65 0.08 5.00
82 INT301641 Irs2 Negative_regulation of Transcription of Pck1 1 0.03 0.65 0.08 5.00
83 INT300192 Gene_expression of APOA1 Positive_regulation of HSD11B1 1 0.16 1.08 0.08 5.00
84 INT301619 Positive_regulation of Irs1 Positive_regulation of Gene_expression of Srebf1 1 0.10 0.67 0.08 5.00
85 INT301628 Irs2 Negative_regulation of Transcription of G6pc 1 0.04 0.65 0.08 5.00
86 INT301646 Srebf1 Negative_regulation of Gene_expression of Irs2 1 0.08 0.62 0.08 5.00
87 INT301613 Binding of Fabp4 and Cd36 1 0.05 0.38 0.08 5.00
88 INT301645 Binding of Alb and Slc27a1 1 0.02 0.38 0.08 5.00
89 INT301631 Gene_expression of Mapk8 Positive_regulation of Phosphorylation of Irs1 1 0.09 0.72 0.08 5.00
90 INT301651 Binding of Alb and Fabp4 1 0.01 0.38 0.08 5.00
91 INT301649 Irs1 Negative_regulation of Transcription of G6pc 1 0.05 0.65 0.08 5.00
92 INT173130 Binding of INS and PPARA 2 0.04 1.8 0.08 5.00
93 INT301614 Binding of Slc27a1 and Cd36 1 0.09 0.38 0.08 5.00
94 INT301659 Gene_expression of Mapk8 Positive_regulation of Positive_regulation of Srebf1 1 0.33 0.8 0.08 5.00
95 INT301656 Ins1 Positive_regulation of Srebf1 1 0.02 0.73 0.07 5.00
96 INT239346 Olfr642 Positive_regulation of Lcat 1 0.00 1.06 0.07 5.00
97 INT301623 Ins1 Positive_regulation of Slc27a2 1 0.01 0.37 0.07 5.00
98 INT301632 Binding of Dbi and Fabp1 1 0.13 0.49 0.07 5.00
99 INT301658 Ins1 Positive_regulation of Slc27a4 1 0.01 0.37 0.07 5.00
100 INT174901 Binding of GSPT2 and GTSE1 1 0.01 1.28 0.07 5.00
101 INT239327 Positive_regulation of Binding of Lcat and Hdl1 1 0.06 1.52 0.06 5.00
102 INT239331 RCT Positive_regulation of Lcat 1 0.08 1.08 0.06 5.00
103 INT239354 CETP Positive_regulation of Lcat 1 0.28 1.09 0.06 5.00
104 INT239326 Binding of Lcat and Hdl1 1 0.05 1.52 0.06 5.00
105 INT301496 PPA1 Negative_regulation of CYP4F3 1 0.01 0.69 0.05 5.00
106 INT344719 Hdl1 Positive_regulation of Plat 1 0.10 1.23 0.05 5.00
107 INT239318 Binding of Cor and Hdl1 1 0.07 1.69 0.05 5.00
108 INT301497 UBXN11 Negative_regulation of CYP4F3 1 0.37 0.69 0.05 5.00
109 INT344703 Hdl1 Negative_regulation of Gene_expression of Serpine1 1 0.07 1.26 0.05 5.00
110 INT301653 Mlxipl Positive_regulation of Gene_expression of Scd1 1 0.08 0.5 0.05 5.00
111 INT239334 Ppara Negative_regulation of Gene_expression of Apo 1 0.06 1.18 0.05 5.00
112 INT290182 Binding of CETP and PLTP 1 0.26 3.31 0.05 5.00
113 INT239320 Eef1a2 Negative_regulation of Hmgcr 1 0.06 0.89 0.04 5.00
114 INT301627 Binding of Fabp1 and Ppara 1 0.21 0.49 0.04 5.00
115 INT301661 Binding of CYP2B6 and Ros1 1 0.02 0.64 0.04 5.00
116 INT290180 Binding of APOB and PLTP 1 0.19 0.6 0.04 5.00
117 INT188903 MUC5AC Positive_regulation of LDHA 1 0.00 1.2 0.04 5.00
118 INT301647 Negative_regulation of Mapk8 Positive_regulation of Irs1 1 0.08 0.83 0.04 5.00
119 INT301626 Mapk8 Positive_regulation of Irs1 1 0.09 0.83 0.04 5.00
120 INT290181 Binding of APOE and PLTP 1 0.17 1.61 0.04 5.00
121 INT301643 Binding of Dbi and fa 1 0.05 0.45 0.03 5.00
122 INT239338 Arg2 Positive_regulation of RCT 1 0.01 1.15 0.03 5.00
123 INT247439 Binding of APOA1 and HSD11B1 3 0.32 5.01 0.03 5.00
124 INT301667 Tlr4 Positive_regulation of Gene_expression of CYBB 1 0.01 0.84 0.03 5.00
125 INT301662 Binding of Tlr4 and Positive_regulation of Gene_expression of CYBB 1 0.01 0.84 0.03 5.00
126 INT173199 CNOT4 Regulation of Regulation of Myc 1 0.01 0.66 0.03 5.00
127 INT239330 Positive_regulation of Ppara Positive_regulation of Hdl1 1 0.05 1.17 0.03 5.00
128 INT199665 Binding of Fxn and Lamtor3 1 0.00 0.16 0.03 5.00
129 INT239345 Apoa1 Positive_regulation of RCT 1 0.02 1.15 0.03 5.00
130 INT301622 Binding of Fabp4 and fa 1 0.01 0.45 0.03 5.00
131 INT239351 Binding of CETP and Ldlr 1 0.15 1.01 0.03 5.00
132 INT300191 Binding of C1S and HSD11B1 1 0.13 1.75 0 5.00
133 INT344708 Hdl1 Positive_regulation of Gene_expression of Plat 1 0.08 1.26 0 5.00
134 INT239332 Hdl1 Positive_regulation of Gene_expression of Apoa1 1 0.04 0.84 0 5.00
135 INT301633 Binding of Ros1 and Cyb5 1 0.00 0.41 0 5.00
136 INT239325 Eef1a2 Negative_regulation of Lipc 1 0.11 0.84 0 5.00
137 INT300195 Binding of C1S and CHDH 1 0.23 2.51 0 5.00
138 INT344720 Niacr1 Negative_regulation of Binding of Hdl1 1 0.17 1.13 0 5.00
139 INT187423 MTTP Regulation of Localization of Cd320 1 0.10 0.81 0 5.00
140 INT301640 Positive_regulation of Cyp2e1 Positive_regulation of Gene_expression of Ros1 1 0.03 0.25 0 5.00
141 INT190890 Binding of RORA and Grip1 1 0.00 0.09 0 5.00
142 INT344722 Binding of Lig3 and Chdh 1 0.00 1.48 0 5.00
143 INT239343 Hdl1 Positive_regulation of Gene_expression of Cor 1 0.09 0.84 0 5.00
144 INT239349 Hdl1 Negative_regulation of Tbxa2r 1 0.03 3.37 0 5.00
145 INT290193 Binding of APOA1 and Hdl1 1 0.01 1 0 5.00
146 INT301635 Ppara Positive_regulation of Gene_expression of Fabp1 1 0.26 0.29 0 5.00
147 INT301657 Binding of Dbi and Ppara 1 0.26 0.23 0 5.00
148 INT301644 Fabp4 Positive_regulation of fa 1 0.01 0 0 5.00
149 INT301629 Ins1 Positive_regulation of Mlxipl 1 0.00 0.36 0 5.00
150 INT301636 Slc27a1 Positive_regulation of Fabp4 1 0.01 0 0 5.00
151 INT301621 Ppara Positive_regulation of Gene_expression of Mttp 1 0.22 0.59 0 5.00
152 INT301669 PPA1 Positive_regulation of Ppara 1 0.02 0.14 0 5.00
153 INT173127 Binding of INS and SORBS1 1 0.02 0.22 0 5.00
154 INT239353 CETP Regulation of Apoa1 1 0.16 0.65 0 5.00
155 INT227399 Binding of D5Mit424 and Alms1 1 0.01 0.71 0 5.00
156 INT173123 Binding of HNF4A and PPARA 1 0.10 0.19 0 5.00
157 INT239342 Lcat Regulation of Apoa1 1 0.16 0.65 0 5.00
158 INT301650 Ins1 Positive_regulation of Dbi 1 0.02 0.23 0 5.00
159 INT344711 Nr1h3 Regulation of Abcg1 1 0.03 1.67 0 5.00
160 INT344717 Binding of Niacr1 and Hdl1 1 0.17 1.51 0 5.00
161 INT300194 HSD11B1 Negative_regulation of CHDH 1 0.08 2.19 0 5.00
162 INT344723 Niacr1 Positive_regulation of Binding of APOB 1 0.31 1.05 0 5.00
163 INT301620 Positive_regulation of Binding of Ros1 and Scd1 1 0.03 0.41 0 5.00
164 INT344712 Nr1h3 Regulation of Abca1 1 0.03 1.68 0 5.00
165 INT344716 Binding of Hdl1 and Chdh 1 0.03 3.24 0 5.00
166 INT239319 Pltp Regulation of Apoa1 1 0.22 0.65 0 5.00
167 INT301652 Binding of Ros1 and Scd1 1 0.02 0.41 0 5.00
168 INT300197 Binding of APOA1 and C1S 1 0.39 3.56 0 5.00
169 INT239350 Eef1a2 Positive_regulation of Apoa1 1 0.22 0.86 0 5.00
170 INT301624 Slc27a1 Positive_regulation of fa 1 0.03 0 0 5.00
171 INT301664 UBXN11 Positive_regulation of Negative_regulation of Cpt1a 1 0.27 0.37 0 5.00
172 INT300196 Binding of HSD11B1 and CHDH 1 0.07 4.01 0 5.00
173 INT239352 Binding of C1S and Hdl1 1 0.06 1.73 0 5.00
174 INT227398 Binding of H2afy and Alms1 1 0.01 1.42 0 5.00
175 INT301634 Positive_regulation of Binding of Ros1 and Cyb5 1 0.00 0.41 0 5.00
176 INT300198 Positive_regulation of Binding of C1S and CHDH 1 0.31 1.63 0 5.00
177 INT301639 Positive_regulation of Mlxipl Positive_regulation of Gene_expression of Pklr 1 0.03 0.52 0 5.00
178 INT301654 Binding of Slc27a2 and Slc27a5 1 0.15 0.18 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hypolipidemia. They are ordered first by their pain relevance and then by number of times they were reported in Hypolipidemia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT300233 Positive_regulation of Gene_expression of LCAT 1 0.29 0.98 0 100.00
2 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 100.00
3 INT41986 Positive_regulation of Gene_expression of HSD11B1 26 0.49 32.84 1.52 100.00
4 INT546 Binding of ALB 311 0.48 85.98 60.14 100.00
5 INT187415 Gene_expression of LCAT 3 0.39 1.26 0 99.96
6 INT94563 Gene_expression of H2-Q10 7 0.42 7 0.88 99.80
7 INT82177 Negative_regulation of H2-Q10 5 0.58 5.83 0.45 99.80
8 INT154986 Binding of CRX 3 0.24 3.87 0.53 99.78
9 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 99.78
10 INT70615 Binding of TXNRD1 25 0.36 12.15 1.27 99.76
11 INT17686 Negative_regulation of Hdl1 72 0.36 81.85 7.74 99.72
12 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 99.68
13 INT95130 Positive_regulation of KCNA6 1 0.21 2.35 0.16 99.36
14 INT10671 Regulation of CRX 4 0.53 6.29 1.78 99.32
15 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04 99.28
16 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 99.26
17 INT160579 Negative_regulation of Tmprss15 1 0.18 0.4 0.09 99.26
18 INT48541 Positive_regulation of Kcna5 12 0.69 5.51 6.35 98.96
19 INT1873 Gene_expression of MRAP 51 0.76 31.75 13.92 98.24
20 INT190874 Negative_regulation of Gene_expression of Apoa1 1 0.15 0.9 0.2 98.08
21 INT187422 Negative_regulation of MTTP 23 0.57 11.75 0.24 97.96
22 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 97.92
23 INT181886 Gene_expression of Apoa1 40 0.64 40.53 4.56 97.76
24 INT239412 Binding of ABL1 8 0.28 5.39 0.18 97.62
25 INT194794 Binding of TTPA 7 0.08 2.56 0.57 97.40
26 INT95128 Positive_regulation of KCNA1 8 0.41 4.28 2.19 96.88
27 INT36453 Binding of ABCA1 48 0.45 19.9 10.84 96.84
28 INT205596 Negative_regulation of COQ10A 22 0.51 15.61 2.77 96.72
29 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32 96.04
30 INT117662 Gene_expression of ABL1 21 0.69 18.76 0.39 96.04
31 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95 96.04
32 INT199661 Negative_regulation of TTPA 2 0.04 1.84 0 95.98
33 INT190081 Gene_expression of Abca1 21 0.65 18.18 2.45 95.92
34 INT114313 Binding of RHO 7 0.36 1.45 0.36 94.80
35 INT198662 Positive_regulation of CD36 14 0.68 7.73 2.36 94.24
36 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 94.00
37 INT314 Positive_regulation of Ren 212 0.70 66.68 55.56 93.56
38 INT115300 Negative_regulation of Napa 7 0.23 1 2.68 92.72
39 INT19414 Positive_regulation of Localization of ADRA1D 2 0.49 0.89 0.35 92.64
40 INT256 Localization of ADRA1D 11 0.78 2.91 6.85 92.04
41 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 91.88
42 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 91.76
43 INT19413 Localization of Serpina3a 1 0.23 0.89 0.14 91.72
44 INT94341 Gene_expression of D9Mit53 1 0.00 1.11 0.12 91.60
45 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 91.28
46 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 91.08
47 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 90.84
48 INT239296 Negative_regulation of Abca1 3 0.26 3.83 0.04 90.48
49 INT24332 Regulation of Hdl1 28 0.45 45.45 4.26 90.48
50 INT1631 Binding of Hdl1 42 0.36 49.22 2.92 90.16
51 INT84541 Binding of Tapbp 3 0.31 2.21 0.29 89.80
52 INT186622 Negative_regulation of Chol1 9 0.42 3.86 0.32 89.68
53 INT186638 Negative_regulation of DHCR7 1 0.19 0.78 0 89.68
54 INT122584 Negative_regulation of Gene_expression of PPARA 56 0.58 37.61 9.76 89.20
55 INT150165 Gene_expression of MTTP 21 0.75 10.1 0.73 89.12
56 INT53184 Negative_regulation of CYP27A1 46 0.57 16.04 5.28 89.08
57 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 89.08
58 INT30738 Negative_regulation of Gene_expression of ALB 32 0.59 19.01 5.04 88.52
59 INT309255 Gene_expression of NDUFV1 1 0.01 2.33 0 88.00
60 INT162141 Localization of CRX 3 0.11 4.24 1.16 87.96
61 INT338075 Regulation of Localization of CRX 1 0.06 1 0 87.96
62 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 87.40
63 INT108917 Positive_regulation of CRX 23 0.50 21.32 10.5 87.28
64 INT173181 Regulation of Gene_expression of PPA1 1 0.04 0.83 0.17 86.72
65 INT173170 Gene_expression of PPA1 5 0.06 3.11 0.47 86.32
66 INT226768 Positive_regulation of Negative_regulation of Hdl1 3 0.29 6.34 0.2 85.84
67 INT1123 Positive_regulation of CD79A 74 0.70 51.96 7.14 85.80
68 INT214574 Positive_regulation of SDC1 4 0.32 3.24 1.28 85.80
69 INT15772 Negative_regulation of Hdlcl1 17 0.41 15.77 1.45 85.12
70 INT300226 Regulation of DGAT1 1 0.01 1.67 0.06 85.04
71 INT16608 Positive_regulation of FFAR1 40 0.37 18.48 3.59 84.80
72 INT109594 Positive_regulation of ABL1 10 0.49 7.19 0.05 84.60
73 INT205594 Gene_expression of COQ10A 19 0.67 12.53 2.56 84.56
74 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 84.16
75 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 84.00
76 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 83.68
77 INT41985 Regulation of Regulation of HSD11B1 2 0.44 1.6 0.17 82.88
78 INT11957 Negative_regulation of LPA 52 0.59 39.09 6.84 82.80
79 INT57557 Negative_regulation of VLDLR 2 0.19 1.23 0.08 82.80
80 INT17913 Regulation of HSD11B1 87 0.60 93.23 6.04 81.52
81 INT190881 Positive_regulation of Rora 2 0.43 1.76 2.71 81.32
82 INT181879 Negative_regulation of Apoa1 8 0.55 8.18 1.11 80.80
83 INT42077 Negative_regulation of Slc37a2 2 0.42 1.87 0.08 80.80
84 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 80.36
85 INT309245 Binding of SETX 1 0.08 1.98 0.06 80.04
86 INT239305 Negative_regulation of Cand1 1 0.57 4.98 0.04 78.84
87 INT65245 Gene_expression of Nos3 121 0.78 98.14 41.56 78.68
88 INT121242 Positive_regulation of Gene_expression of Nos3 37 0.69 31.96 12.71 78.68
89 INT14442 Localization of GBE1 19 0.31 9.09 5.03 77.92
90 INT5114 Gene_expression of Ptgis 41 0.50 21.43 8.1 77.40
91 INT15917 Positive_regulation of Gene_expression of Ptgis 5 0.35 3.69 0.95 77.40
92 INT73431 Positive_regulation of Nos3 82 0.65 53.22 11.61 77.12
93 INT300232 Gene_expression of PCSK9 1 0.57 0.8 0 76.32
94 INT239409 Transcription of APOB 3 0.65 1.86 0.06 75.96
95 INT40877 Positive_regulation of APOB 35 0.68 32.47 1.86 75.96
96 INT290184 Binding of PLTP 1 0.48 4.53 0.03 75.96
97 INT9254 Negative_regulation of LDHA 23 0.43 13.3 2.2 75.76
98 INT1168 Binding of PROC 62 0.38 44.15 9.04 75.00
99 INT102034 Positive_regulation of Ppard 10 0.69 3.97 3.17 75.00
100 INT215378 Protein_catabolism of Ppara 12 0.86 5.12 2.14 75.00
101 INT34585 Negative_regulation of Positive_regulation of HSD11B1 31 0.57 43.54 2.47 74.96
102 INT131674 Negative_regulation of HEXB 3 0.10 3.78 0.32 74.68
103 INT114330 Binding of MPZ 21 0.32 25.58 2.14 74.56
104 INT41314 Gene_expression of GGTLC1 9 0.59 5.61 1.79 72.40
105 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 72.16
106 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 71.96
107 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 71.56
108 INT163872 Negative_regulation of TSHR 4 0.42 3.52 0.49 70.56
109 INT47994 Negative_regulation of Lipg 45 0.50 27.19 7.24 70.24
110 INT34590 Gene_expression of ALPP 199 0.75 89.85 15.1 69.92
111 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 69.84
112 INT133876 Positive_regulation of Gene_expression of Ros1 141 0.32 75.55 27.45 69.84
113 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53 69.60
114 INT239411 Localization of APOB 10 0.76 5.71 0.04 69.48
115 INT239302 Positive_regulation of Gene_expression of Abca1 9 0.32 9.1 1.06 69.40
116 INT6133 Negative_regulation of Serpinc1 56 0.58 42.8 8.35 69.08
117 INT180454 Negative_regulation of Apoa2 6 0.42 7.42 0.2 69.00
118 INT187410 Localization of Cd320 14 0.78 9.03 0.31 68.68
119 INT504 Gene_expression of GPT 42 0.75 27.54 3.99 68.16
120 INT573 Negative_regulation of C3 60 0.59 41.37 7.78 67.84
121 INT31582 Gene_expression of Hdl1 103 0.66 118.95 6.42 66.56
122 INT9384 Positive_regulation of Positive_regulation of LDHA 3 0.50 5.5 0.52 66.56
123 INT66646 Regulation of Chdh 13 0.44 16.24 8.84 66.20
124 INT84891 Gene_expression of PPARD 10 0.78 6.8 3.64 64.04
125 INT101516 Positive_regulation of PPARD 8 0.49 4.75 2.19 64.04
126 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 62.72
127 INT251 Regulation of INS 398 0.62 232.47 55.04 61.76
128 INT128609 Gene_expression of C1S 18 0.75 17.36 0.98 60.80
129 INT190882 Regulation of Gene_expression of Apoa1 4 0.23 3.67 0.43 60.24
130 INT15531 Regulation of FFAR1 9 0.48 4.25 0.89 59.64
131 INT56374 Gene_expression of AMBP 34 0.54 35.85 6.25 58.24
132 INT3286 Positive_regulation of Gpt 90 0.69 45.08 28.34 57.92
133 INT49862 Negative_regulation of Positive_regulation of Gpt 8 0.41 3.49 2.6 57.92
134 INT116848 Negative_regulation of Chdh 10 0.42 19.68 1.95 56.04
135 INT9466 Binding of APOB 27 0.41 19.36 1.56 56.00
136 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 55.20
137 INT239413 Binding of PADI1 6 0.24 0.97 0 55.20
138 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 54.56
139 INT197173 Positive_regulation of Cyp4a10 29 0.62 15.68 1.61 54.52
140 INT197174 Positive_regulation of Gene_expression of Cyp4a10 17 0.67 8.65 1.4 54.52
141 INT187413 Positive_regulation of Localization of Cd320 3 0.49 1.98 0.03 54.12
142 INT197166 Gene_expression of Cyp4a10 27 0.75 15.63 1.81 54.00
143 INT24042 Gene_expression of MUC5AC 98 0.77 74.99 6.18 53.84
144 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41 53.52
145 INT142800 Positive_regulation of Ldlr 21 0.68 14.75 0.6 52.72
146 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 50.00
147 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66 50.00
148 INT122041 Binding of Ppara 308 0.48 189.17 51.48 50.00
149 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04 50.00
150 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55 50.00
151 INT115385 Negative_regulation of Ppara 154 0.58 129.05 27.58 50.00
152 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 50.00
153 INT7475 Positive_regulation of Hdl1 138 0.67 175.81 15.05 50.00
154 INT93482 Localization of Rela 56 0.78 24.52 14.82 50.00
155 INT122037 Regulation of Ppara 93 0.62 56.28 12.89 50.00
156 INT194462 Localization of Ppara 94 0.78 68.33 12.09 50.00
157 INT79720 Positive_regulation of Cat 57 0.70 31.81 10.11 50.00
158 INT120509 Gene_expression of Cat 65 0.77 50.9 9.75 50.00
159 INT123701 Negative_regulation of VDR 61 0.59 48.94 9.67 50.00
160 INT138799 Regulation of Gene_expression of Ppara 40 0.60 29.42 6.89 50.00
161 INT194479 Phosphorylation of Ppara 47 0.81 30.36 6.6 50.00
162 INT91147 Positive_regulation of Positive_regulation of Ppara 30 0.69 19.31 5.56 50.00
163 INT120511 Positive_regulation of Gene_expression of Cat 26 0.69 19.82 5.2 50.00
164 INT122038 Transcription of Ppara 35 0.71 20.5 5.12 50.00
165 INT181186 Binding of Rxra 78 0.35 14.93 4.87 50.00
166 INT106524 Phosphorylation of Jun 23 0.80 15.35 4.78 50.00
167 INT169492 Gene_expression of Mirlet7a-1 27 0.67 14.85 4.73 50.00
168 INT93483 Negative_regulation of Localization of Rela 11 0.57 5.1 4.19 50.00
169 INT169495 Negative_regulation of Mirlet7a-1 10 0.58 4 3.53 50.00
170 INT89966 Negative_regulation of Fas 26 0.58 24.83 3.5 50.00
171 INT50080 Binding of APOE 38 0.45 29.61 2.67 50.00
172 INT211984 Regulation of Binding of Ppara 11 0.45 9.55 1.87 50.00
173 INT169491 Negative_regulation of Gene_expression of Mirlet7a-1 11 0.37 6.22 1.54 50.00
174 INT187411 Gene_expression of Cd320 23 0.75 12.1 1.39 50.00
175 INT190880 Binding of Ncor2 11 0.27 2.24 1.34 50.00
176 INT122040 Positive_regulation of Transcription of Ppara 9 0.50 3.97 1.33 50.00
177 INT197167 Positive_regulation of Localization of Ppara 18 0.67 9.51 1.21 50.00
178 INT123877 Negative_regulation of ABL1 40 0.57 27.94 1.17 50.00
179 INT227548 Negative_regulation of Localization of Ppara 7 0.38 4.1 1.17 50.00
180 INT169496 Localization of Mirlet7a-1 3 0.65 0.42 1.15 50.00
181 INT129425 Negative_regulation of Ldlr 22 0.42 17.15 0.97 50.00
182 INT211557 Gene_expression of Scarb1 30 0.75 5.03 0.94 50.00
183 INT236104 Positive_regulation of Negative_regulation of Ppara 6 0.59 6.91 0.91 50.00
184 INT175945 Gene_expression of Acox1 7 0.65 2.77 0.68 50.00
185 INT187407 Negative_regulation of Gene_expression of Cd320 7 0.57 5.05 0.67 50.00
186 INT307186 Negative_regulation of Phosphorylation of Jun 4 0.10 2.91 0.61 50.00
187 INT111198 Gene_expression of Fasn 8 0.55 2.54 0.52 50.00
188 INT235512 Transcription of Lpl 10 0.42 2.76 0.49 50.00
189 INT203949 Regulation of Srebf1 8 0.38 3.19 0.48 50.00
190 INT100822 Localization of Fas 8 0.74 6.13 0.48 50.00
191 INT26073 Gene_expression of Scd1 17 0.70 9.17 0.47 50.00
192 INT170208 Negative_regulation of Lpl 15 0.49 6.07 0.45 50.00
193 INT28059 Positive_regulation of Apol7b 7 0.03 8.19 0.44 50.00
194 INT145045 Gene_expression of Med1 29 0.65 5.37 0.39 50.00
195 INT194468 Positive_regulation of Phosphorylation of Ppara 4 0.46 2.11 0.38 50.00
196 INT200249 Binding of Ahrr 4 0.01 0.2 0.38 50.00
197 INT253540 Positive_regulation of Transcription of Lpl 3 0.29 1.43 0.3 50.00
198 INT307183 Positive_regulation of Gene_expression of Scarb1 1 0.07 0.93 0.22 50.00
199 INT105327 Positive_regulation of Ncoa2 3 0.06 1.85 0.21 50.00
200 INT118482 Negative_regulation of Fasn 3 0.31 0.83 0.21 50.00
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