D:Hypomagnesemia

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Disease Term
Synonyms Hypomagnesaemia, Hypomagnesaemia Disorder, Hypomagnesaemia Syndrome, Hypomagnesemia Disorder, Hypomagnesemia Syndrome, LOW BLOOD MAGNESIUM LEVEL, LOW BLOOD MAGNESIUM LEVELS, Magnesium Deficiency Syndrome
Documents 160
Hot Single Events 48
Hot Interactions 3

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hypomagnesemia. They are ordered first by their relevance to Hypomagnesemia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT146937 Egf Regulation of Trpm6 1 0.03 0.27 0.11 97.16
2 INT352995 IPMK Regulation of PDGFA 1 0.00 0.66 0 87.88
3 INT352994 IPMK Regulation of VEGFA 1 0.00 0.66 0 87.88
4 INT170832 Cftr Regulation of Scnn1a 2 0.16 1.2 0.67 49.16
5 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 5.00
6 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 5.00
7 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34 5.00
8 INT291967 INA Positive_regulation of NA 1 0.00 0.98 0.14 5.00
9 INT315829 Binding of EGFR and TKT 1 0.03 1.14 0.12 5.00
10 INT270731 Binding of AGTR1 and ACE 1 0.02 0.67 0.09 5.00
11 INT327451 HTN1 Positive_regulation of Adra1a 1 0.00 1.36 0.03 5.00
12 INT327101 Binding of AREG and EGF 1 0.05 0.35 0 5.00
13 INT270732 DBP Negative_regulation of SHBG 1 0.00 1.08 0 5.00
14 INT289836 BEST1 Positive_regulation of Gene_expression of Car2 1 0.03 0.08 0 5.00
15 INT345506 Binding of EGFR and FNDC3A 1 0.00 0.08 0 5.00
16 INT327100 Binding of BTC and EGF 1 0.04 0.35 0 5.00
17 INT277897 EGF Positive_regulation of CALCRL 1 0.00 0.77 0 5.00
18 INT327099 Binding of EGF and EREG 1 0.05 0.35 0 5.00
19 INT277896 EGF Positive_regulation of TKT 1 0.02 0.76 0 5.00
20 INT277766 EGFR Regulation of Gene_expression of VEGFA 1 0.54 0.14 0 5.00
21 INT277772 Binding of EGFR and fc 1 0.01 0.57 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hypomagnesemia. They are ordered first by their pain relevance and then by number of times they were reported in Hypomagnesemia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7 100.00
2 INT175416 Regulation of Negative_regulation of EGFR 4 0.60 3.94 0.14 99.76
3 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54 99.76
4 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 99.62
5 INT21901 Negative_regulation of Egf 25 0.58 10.46 4.99 99.50
6 INT11154 Binding of EGFR 149 0.48 96.23 6.29 99.50
7 INT4679 Negative_regulation of RAPGEF5 55 0.57 47.51 4.55 99.26
8 INT119506 Negative_regulation of Egfr 32 0.55 23.75 3.67 99.06
9 INT129933 Negative_regulation of SLC12A3 2 0.38 3.67 0.08 98.72
10 INT1536 Negative_regulation of NA 244 0.55 52.67 59.79 98.38
11 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 98.14
12 INT3823 Positive_regulation of ALPI 27 0.69 19.49 2.15 98.14
13 INT22812 Positive_regulation of PTRH1 4 0.49 3.06 0.43 98.14
14 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 97.88
15 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 97.88
16 INT205021 Positive_regulation of Gene_expression of Egfr 3 0.64 4.15 0.05 97.40
17 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 97.20
18 INT146936 Gene_expression of Trpm6 2 0.28 0.22 0.25 97.20
19 INT124954 Gene_expression of Egfr 26 0.75 15.08 3.12 97.00
20 INT289828 Negative_regulation of Bsnd 1 0.07 0.7 0 96.52
21 INT289817 Negative_regulation of Clcnkb 1 0.09 0.7 0 96.08
22 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 95.76
23 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 95.76
24 INT123078 Negative_regulation of Kcnj1 2 0.10 0.87 1.09 95.68
25 INT91360 Negative_regulation of Slc12a2 16 0.54 10.46 12.89 95.44
26 INT192806 Binding of SSRP1 11 0.27 9.12 0.37 94.84
27 INT289815 Gene_expression of Clcnkb 1 0.10 0.97 0.1 92.36
28 INT289820 Regulation of Gene_expression of Clcnkb 1 0.07 0.97 0.1 92.36
29 INT134512 Negative_regulation of Dct 4 0.22 2.31 0.22 91.52
30 INT50948 Gene_expression of SLC12A2 6 0.59 4.55 0.22 90.80
31 INT96994 Phosphorylation of EGFR 99 0.82 52.75 7.33 90.48
32 INT118292 Negative_regulation of Phosphorylation of EGFR 27 0.59 13.62 1.54 90.48
33 INT2780 Regulation of Gene_expression of Penk 265 0.62 32.45 143.88 90.24
34 INT91703 Negative_regulation of Myoz1 78 0.58 53.78 13.5 89.96
35 INT53927 Positive_regulation of Localization of PTH 8 0.69 5.33 0.09 89.80
36 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 89.52
37 INT2544 Localization of PTH 39 0.81 30.55 2.22 89.44
38 INT129932 Binding of SLC12A3 1 0.33 1.92 0.08 88.88
39 INT223597 Negative_regulation of Binding of EGFR 12 0.43 7.97 0.23 88.08
40 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 85.16
41 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5 85.16
42 INT49128 Gene_expression of IGF1R 35 0.63 23.48 1.39 82.16
43 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 81.00
44 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 80.96
45 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 80.96
46 INT12057 Regulation of Negative_regulation of INS 7 0.40 3.92 0.76 80.96
47 INT812 Localization of INS 1026 0.81 515.6 145.31 80.44
48 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 80.24
49 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59 79.12
50 INT41719 Gene_expression of MTOR 27 0.77 19.43 1.44 78.96
51 INT289813 Gene_expression of Bsnd 1 0.07 0.49 0 77.12
52 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 76.96
53 INT11225 Positive_regulation of SLC12A2 3 0.45 1.1 0.6 76.60
54 INT129736 Negative_regulation of Casr 1 0.14 1.28 0.08 76.56
55 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 76.48
56 INT129737 Positive_regulation of Casr 2 0.52 2.39 1.33 72.96
57 INT6761 Binding of CALCA 100 0.48 26.71 62.05 71.20
58 INT72030 Regulation of Binding of CALCA 2 0.54 0.65 0.07 71.20
59 INT192958 Negative_regulation of IGF1R 8 0.30 6.35 0.21 71.08
60 INT28094 Binding of PTH 29 0.37 13.57 3.09 70.16
61 INT192804 Regulation of Binding of PTH 2 0.45 0.43 0 70.16
62 INT266934 Regulation of Binding of EGFR 3 0.45 1.16 0.07 69.60
63 INT192805 Binding of PTMS 2 0.36 0.65 0 69.12
64 INT192810 Regulation of Binding of PTMS 1 0.44 0.43 0 69.12
65 INT43900 Gene_expression of RASA1 13 0.58 12 2.03 68.92
66 INT217070 Gene_expression of Acsm3 8 0.25 6.27 1.75 68.76
67 INT11160 Regulation of Gene_expression of EGFR 27 0.62 22.05 0.96 68.12
68 INT24863 Negative_regulation of SLC12A2 12 0.44 1.85 1.61 66.68
69 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 64.64
70 INT481 Regulation of Localization of Ren 37 0.62 5.95 11.61 64.20
71 INT46 Localization of Ren 233 0.81 46.15 62.44 63.80
72 INT14916 Binding of RASA1 15 0.37 13.64 1.44 63.52
73 INT34057 Negative_regulation of Gene_expression of IFNA1 65 0.58 43.46 17.25 63.44
74 INT192803 Negative_regulation of Gene_expression of SSRP1 1 0.05 2.36 0 63.44
75 INT289827 Binding of Clcnkb 1 0.06 0.39 0 60.56
76 INT289831 Binding of Bsnd 1 0.06 0.38 0 58.80
77 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 57.68
78 INT171361 Regulation of Egfr 16 0.62 8.36 0.81 57.60
79 INT192807 Gene_expression of SSRP1 14 0.49 19.28 1.15 56.48
80 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59 55.52
81 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 54.88
82 INT118791 Binding of AKT1 32 0.48 15.51 2.25 54.48
83 INT142682 Binding of EMR1 2 0.26 2.4 0.06 54.48
84 INT132864 Binding of Htt 15 0.46 2.34 0.38 50.00
85 INT123130 Positive_regulation of Positive_regulation of AKT1 22 0.49 11.77 1.83 49.60
86 INT120562 Negative_regulation of Egfr 108 0.59 79.38 3.11 48.84
87 INT28145 Binding of PAPPA 26 0.48 7.4 4.96 46.92
88 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 45.16
89 INT760 Negative_regulation of Scn8a 11 0.42 1.65 5.6 44.08
90 INT192809 Negative_regulation of SSRP1 2 0.04 4.06 0.33 39.88
91 INT213923 Positive_regulation of MTOR 16 0.65 9.28 0.7 39.12
92 INT185350 Negative_regulation of Gene_expression of Egfr 24 0.59 13.21 0.35 37.16
93 INT66193 Negative_regulation of Btd 3 0.59 3.39 0.32 37.04
94 INT120563 Positive_regulation of Gene_expression of Egfr 56 0.70 46.19 1.82 36.64
95 INT8101 Binding of INCENP 42 0.31 16.2 6.68 36.32
96 INT173090 Regulation of INCENP 24 0.09 9.45 2.16 34.68
97 INT264641 Binding of AES 25 0.42 18.56 6.98 34.48
98 INT114246 Positive_regulation of Negative_regulation of EGFR 13 0.49 8.67 0.7 30.32
99 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 28.64
100 INT82611 Negative_regulation of SRC 30 0.57 20.16 5.47 27.92
101 INT19993 Negative_regulation of Ren1 43 0.58 20.89 5.04 25.00
102 INT98975 Positive_regulation of Hmgcr 7 0.16 3.4 1.06 25.00
103 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 21.36
104 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 13.92
105 INT11650 Negative_regulation of Gpt 122 0.59 69.15 30.36 12.16
106 INT16165 Regulation of DMD 114 0.60 35.13 3.64 10.44
107 INT199004 Gene_expression of ARMC9 43 0.58 17.72 1.32 9.24
108 INT477 Localization of Avp 813 0.81 131.58 300.4 5.00
109 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
110 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
111 INT738 Regulation of POMC 459 0.62 111.19 243.74 5.00
112 INT6354 Localization of Gabrg1 321 0.74 41.41 186.74 5.00
113 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
114 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 5.00
115 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 5.00
116 INT695 Binding of POMC 304 0.48 56.66 126.85 5.00
117 INT6323 Positive_regulation of Gabrg1 213 0.70 45.08 124.34 5.00
118 INT4259 Positive_regulation of Npr1 262 0.70 49.37 123.11 5.00
119 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 5.00
120 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 5.00
121 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 5.00
122 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 5.00
123 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 5.00
124 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28 5.00
125 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74 5.00
126 INT251 Regulation of INS 398 0.62 232.47 55.04 5.00
127 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 5.00
128 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
129 INT9210 Regulation of IL6 166 0.62 125.61 49.95 5.00
130 INT654 Localization of REN 250 0.81 75.12 47.86 5.00
131 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76 5.00
132 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32 5.00
133 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 5.00
134 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
135 INT17561 Localization of Car2 303 0.79 60.95 44.52 5.00
136 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 5.00
137 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 5.00
138 INT6357 Positive_regulation of Localization of Gabrg1 53 0.41 7.03 39.21 5.00
139 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
140 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
141 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23 5.00
142 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 5.00
143 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 5.00
144 INT660 Negative_regulation of REN 194 0.59 82.06 29.46 5.00
145 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47 5.00
146 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6 5.00
147 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
148 INT16428 Positive_regulation of Gtf3a 135 0.20 106.44 26.67 5.00
149 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 5.00
150 INT11157 Binding of EGF 88 0.48 53.73 21.25 5.00
151 INT33327 Positive_regulation of Gene_expression of Gabrg1 39 0.69 9.68 18.82 5.00
152 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 5.00
153 INT50579 Binding of CYP3A4 84 0.48 17.52 17.45 5.00
154 INT22068 Binding of CALCRL 53 0.41 6.14 17.32 5.00
155 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03 5.00
156 INT3206 Positive_regulation of Got1 39 0.69 19.36 17.02 5.00
157 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92 5.00
158 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 5.00
159 INT3400 Positive_regulation of pr 57 0.68 36.9 16.24 5.00
160 INT52107 Transcription of IL8 63 0.72 41.66 16.06 5.00
161 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 5.00
162 INT6163 Negative_regulation of INA 39 0.43 2.9 14.8 5.00
163 INT9191 Localization of EDN1 94 0.81 57.01 14.78 5.00
164 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 5.00
165 INT6947 Negative_regulation of Gene_expression of POMC 37 0.59 10.32 14.14 5.00
166 INT18773 Localization of ALB 117 0.80 69.18 13.8 5.00
167 INT655 Positive_regulation of Localization of REN 86 0.70 32.41 13.56 5.00
168 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 5.00
169 INT63104 Negative_regulation of CALCRL 29 0.37 13.62 12.42 5.00
170 INT11288 Negative_regulation of CRH 44 0.00 16.69 12.37 5.00
171 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55 5.00
172 INT25170 Positive_regulation of Localization of Car2 78 0.67 15.25 11.24 5.00
173 INT10009 Positive_regulation of TRH 31 0.67 8.94 11.03 5.00
174 INT8065 Binding of AGT 54 0.48 20.54 10.85 5.00
175 INT701 Localization of IGHE 87 0.80 40.5 10.62 5.00
176 INT130867 Gene_expression of TNFSF11 106 0.77 45.15 10.34 5.00
177 INT94784 Binding of ROS1 113 0.40 71.57 10.26 5.00
178 INT2378 Negative_regulation of SERPINE1 47 0.59 34.55 9.9 5.00
179 INT1372 Regulation of Localization of REN 50 0.62 5.76 9.81 5.00
180 INT5465 Positive_regulation of CALCRL 25 0.49 7.24 9.8 5.00
181 INT2036 Localization of EGF 42 0.77 21.5 9.74 5.00
182 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 5.00
183 INT62166 Positive_regulation of Gene_expression of Gpt 64 0.50 39.13 9.69 5.00
184 INT20664 Binding of ACE 60 0.48 35.27 9.16 5.00
185 INT860 Regulation of ALB 48 0.60 25.11 8.95 5.00
186 INT59165 Binding of fc 67 0.36 37.51 8.68 5.00
187 INT8903 Gene_expression of IFNA2 58 0.71 38.23 8.68 5.00
188 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68 5.00
189 INT8637 Negative_regulation of Dbp 112 0.50 33.28 8.4 5.00
190 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31 5.00
191 INT173808 Positive_regulation of CYP27A1 35 0.68 23.7 7.87 5.00
192 INT32709 Negative_regulation of Hbb 30 0.54 18.27 6.97 5.00
193 INT69289 Negative_regulation of Cftr 44 0.57 13.28 6.97 5.00
194 INT59079 Transcription of PTGS2 30 0.72 14.21 6.52 5.00
195 INT48239 Binding of Gtf3a 52 0.33 23.14 6.45 5.00
196 INT5847 Transcription of FOS 31 0.69 11.11 6.41 5.00
197 INT4144 Gene_expression of SHBG 64 0.68 39.94 6.08 5.00
198 INT93684 Gene_expression of STAT3 66 0.78 34.42 5.94 5.00
199 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93 5.00
200 INT21103 Gene_expression of Dbp 48 0.61 22.6 5.59 5.00
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