D:Hyponatremia

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pChart

Disease Term
Synonyms Evolemic Hyponatraemia, Evolemic Hyponatremia, Hypervolaemic Hyponatraemia, Hypervolaemic Hyponatremia, Hypervolemic Hyponatraemia, HYPERVOLEMIC HYPONATREMIA, Hyponatraemia, Hyponatraemia With Euvolaemia, Hyponatraemia With Euvolemia, Hyponatraemia With Hypervolaemia, Hyponatraemia With Hypervolemia
Documents 586
Hot Single Events 200
Hot Interactions 22

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hyponatremia. They are ordered first by their relevance to Hyponatremia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT52629 Binding of AVP and NMS 1 0.04 1.04 0.21 100.00
2 INT262367 Tcas1 Positive_regulation of Localization of Adh4 1 0.01 1.91 1.01 99.92
3 INT234802 Binding of AQP2 and AVPR2 2 0.15 0.84 0.07 97.12
4 INT284570 Binding of Avp and Il6 1 0.04 2.17 0.13 96.00
5 INT177714 Binding of GALNT3 and REN 1 0.01 2.36 0.12 95.84
6 INT280835 Usf1 Positive_regulation of Gene_expression of Avp 1 0.03 1.06 0 95.12
7 INT280830 Binding of Avp and Usf2 1 0.02 0.53 0 93.48
8 INT280812 Usf2 Positive_regulation of Gene_expression of Avp 1 0.03 0.52 0 93.48
9 INT280829 Binding of Tcf12 and Usf2 1 0.00 0.53 0 93.48
10 INT280851 Binding of Avp and Usf2 Positive_regulation of Gene_expression of Avp 1 0.00 0.53 0 93.48
11 INT241771 Binding of AVP and AVPR1B 1 0.04 0.49 0 93.16
12 INT241773 AVP Regulation of Binding of AVPR1B 1 0.05 0.49 0 93.16
13 INT241780 Binding of AVP and TRGV9 1 0.12 2.41 0.35 93.16
14 INT241770 AVP Regulation of Binding of TRGV9 1 0.11 0.49 0 93.16
15 INT241769 AVP Regulation of Binding of AVPR1A 1 0.11 0.49 0 93.16
16 INT241768 Binding of AVP and AVPR1A 1 0.08 0.49 0 93.16
17 INT87060 IL6 Positive_regulation of Localization of AVP 1 0.59 1.01 0.18 91.96
18 INT241778 AVP Positive_regulation of AVPR1A 1 0.10 1.32 0 91.76
19 INT280844 Binding of Avp and Tcf12 1 0.00 0.52 0 90.08
20 INT158391 Oxt Positive_regulation of Localization of Nppa 2 0.27 0.64 0.03 89.96
21 INT241779 AVP Positive_regulation of TRGV9 1 0.17 0.48 0 89.04
22 INT106630 Binding of GRK5 and PRKCA 1 0.16 0.82 0.19 89.04
23 INT334893 ACE Negative_regulation of Gene_expression of AGT 1 0.03 1.41 0.1 77.28
24 INT241774 Binding of AVPR1A and TRGV9 1 0.02 0.48 0.09 77.24
25 INT280826 Il6 Positive_regulation of Localization of Avp 1 0.01 0.64 0.47 73.76
26 INT280820 S100a8 Positive_regulation of Gene_expression of Crh 1 0.01 0.65 0.19 71.44
27 INT87061 Binding of AVP and IL6 1 0.26 1.04 0.22 70.24
28 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3 69.84
29 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 69.40
30 INT241775 AVP Positive_regulation of Gene_expression of AQP2 1 0.08 0.17 0 63.76
31 INT196627 IL1B Regulation of DNAH8 1 0.00 0.63 0.09 61.44
32 INT196643 IL1B Regulation of NA 1 0.00 0.63 0.09 61.44
33 INT196619 KNG1 Regulation of DNAH8 1 0.00 0.62 0.09 61.08
34 INT196645 KNG1 Regulation of NA 1 0.00 0.62 0.09 61.08
35 INT196606 IFNG Positive_regulation of CFTR 1 0.16 0.45 0.16 58.80
36 INT280816 Crh Positive_regulation of Gene_expression of Pomc 1 0.15 0.28 0.06 51.88
37 INT196640 PTGER2 Negative_regulation of DNAH8 1 0.00 0.46 0.08 50.92
38 INT196611 PTGER2 Negative_regulation of NA 1 0.00 0.46 0.08 50.92
39 INT196628 IFNG Negative_regulation of Gene_expression of DNAH8 1 0.02 0.31 0.05 50.16
40 INT241776 Binding of AVP and Positive_regulation of ADCY1 1 0.06 0.54 0.32 50.00
41 INT241772 AVP Positive_regulation of ADCY1 1 0.09 1.08 0.15 50.00
42 INT241777 Negative_regulation of Binding of AVP and TRGV9 1 0.10 0.75 0.13 50.00
43 INT280810 Avp Negative_regulation of Gene_expression of Pomc 1 0.02 0.22 0.06 48.72
44 INT196634 IFNG Negative_regulation of DNAH8 1 0.03 1.49 0.47 46.16
45 INT196647 IFNG Negative_regulation of NA 1 0.04 0.79 0.24 45.44
46 INT196614 TNF Positive_regulation of Positive_regulation of NA 1 0.03 0.88 0.24 40.40
47 INT196615 TNF Positive_regulation of Negative_regulation of DNAH8 1 0.02 0.88 0.24 40.40
48 INT196620 TNF Positive_regulation of Positive_regulation of DNAH8 1 0.03 0.88 0.24 40.40
49 INT196609 IFNG Positive_regulation of Positive_regulation of NA 1 0.03 0.87 0.24 39.92
50 INT196622 IFNG Positive_regulation of Positive_regulation of DNAH8 1 0.03 0.87 0.24 39.92
51 INT196646 IFNG Positive_regulation of Negative_regulation of DNAH8 1 0.03 0.87 0.24 39.92
52 INT280833 Il1 Positive_regulation of Gene_expression of Crh 1 0.05 0.09 0.17 36.88
53 INT280839 Il6 Positive_regulation of Gene_expression of Crh 1 0.09 0.1 0.19 29.84
54 INT196648 PTGER2 Regulation of DNAH8 1 0.00 0.14 0.12 28.00
55 INT196636 PTGER2 Regulation of NA 1 0.00 0.14 0.12 28.00
56 INT196607 IFNG Regulation of Gene_expression of SCNN1G 1 0.03 0.08 0.03 27.92
57 INT196617 TNF Negative_regulation of Gene_expression of SCNN1G 1 0.02 0.08 0.03 21.68
58 INT297613 Negative_regulation of ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.66 0 21.12
59 INT300957 Binding of IL13 and Il4 1 0.01 0.58 0.48 20.00
60 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99 18.84
61 INT191241 SST Regulation of SAE1 1 0.05 0.89 0.18 17.92
62 INT297614 ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.56 0 17.52
63 INT280815 Vmn1r66 Negative_regulation of Gene_expression of Avp 1 0.00 0.09 0 17.52
64 INT280849 REST Negative_regulation of Gene_expression of Avp 1 0.09 0.09 0 14.40
65 INT280848 Binding of REST and Rest 1 0.02 0.09 0 14.40
66 INT280837 Binding of Rest and Negative_regulation of Gene_expression of Avp 1 0.00 0.09 0 14.16
67 INT280821 Son Regulation of Gene_expression of gr 1 0.01 0.18 0.08 12.96
68 INT196625 TNF Negative_regulation of Positive_regulation of SCNN1G 1 0.02 0.14 0.03 12.48
69 INT280831 Prkaca Positive_regulation of Gene_expression of Crh 1 0.08 0 0 11.76
70 INT345289 CRS Regulation of REN 1 0.03 1.02 0.12 7.52
71 INT280823 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Crh 1 0.08 0.11 0 6.48
72 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2 5.00
73 INT166983 Binding of HLA-B and HSPG2 4 0.08 4.66 0.88 5.00
74 INT196638 TNF Positive_regulation of F2RL1 2 0.09 1.52 0.84 5.00
75 INT196632 IL1B Positive_regulation of F2RL1 2 0.05 1.52 0.84 5.00
76 INT122191 Binding of Crh and Ucn 4 0.36 0.79 0.82 5.00
77 INT329120 Binding of KCNA1 and CNTNAP2 1 0.09 1.23 0.75 5.00
78 INT329119 Binding of CNTN2 and CNTNAP2 1 0.08 2.41 0.73 5.00
79 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72 5.00
80 INT122190 Binding of Crhr1 and Ucn 4 0.49 0.65 0.67 5.00
81 INT352496 AVP Regulation of Gene_expression of CRS 1 0.27 2.47 0.59 5.00
82 INT93063 Binding of gr and Jun 3 0.14 0.79 0.57 5.00
83 INT149473 Avp Positive_regulation of Localization of Pomc 4 0.48 2.64 0.56 5.00
84 INT300956 Il4 Negative_regulation of IL8 1 0.02 0.37 0.48 5.00
85 INT300960 Il4 Negative_regulation of IL1B 1 0.03 0.37 0.48 5.00
86 INT300959 Il4 Negative_regulation of TNF 1 0.03 0.37 0.48 5.00
87 INT300955 Il4 Negative_regulation of Il6 1 0.03 0.37 0.48 5.00
88 INT329116 Binding of LGI1 and CNTNAP2 1 0.38 1.3 0.44 5.00
89 INT329122 Binding of KCNA1 and LGI1 1 0.08 0.29 0.43 5.00
90 INT345288 AGT Positive_regulation of Localization of CCL2 1 0.01 1.5 0.43 5.00
91 INT345291 AGT Positive_regulation of CCL2 1 0.01 1.39 0.43 5.00
92 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39 5.00
93 INT122188 Binding of Crh and Ucn2 2 0.22 0.29 0.38 5.00
94 INT262760 Binding of TEP1 and CD163L1 1 0.00 1.65 0.37 5.00
95 INT122189 Binding of Crhr1 and Ucn2 2 0.08 0.27 0.36 5.00
96 INT196644 PTGER2 Positive_regulation of Gene_expression of NA 1 0.00 0.93 0.35 5.00
97 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34 5.00
98 INT280808 Prkcg Positive_regulation of Transcription of Fos 1 0.02 0.06 0.33 5.00
99 INT280838 Binding of Crh and gr 1 0.06 0 0.33 5.00
100 INT280814 Positive_regulation of Mapk1 Positive_regulation of Transcription of Fos 1 0.02 0.06 0.33 5.00
101 INT196618 Binding of KNG1 and Positive_regulation of NA 1 0.01 0.19 0.32 5.00
102 INT196623 Binding of KNG1 and Positive_regulation of DNAH8 1 0.01 0.19 0.32 5.00
103 INT196605 Binding of DNAH8 and SPANXB1 Positive_regulation of DNAH8 1 0.00 0.08 0.3 5.00
104 INT196604 Binding of DNAH8 and SPANXB1 Positive_regulation of NA 1 0.00 0.08 0.3 5.00
105 INT191240 SAE1 Regulation of Localization of INS 1 0.08 1.15 0.3 5.00
106 INT196641 Binding of KNG1 and Negative_regulation of DNAH8 1 0.01 0.19 0.29 5.00
107 INT196612 Binding of KNG1 and Negative_regulation of NA 1 0.01 0.19 0.29 5.00
108 INT196621 PTGER2 Negative_regulation of Gene_expression of DNAH8 1 0.00 0.33 0.28 5.00
109 INT280827 Positive_regulation of Fos Positive_regulation of Avp 1 0.02 0.08 0.28 5.00
110 INT196631 PTGER2 Negative_regulation of NFKB1 1 0.00 0.32 0.28 5.00
111 INT280825 Mapk1 Positive_regulation of Avp 1 0.01 0.08 0.28 5.00
112 INT280807 Mapk1 Positive_regulation of Positive_regulation of Prkcg 1 0.01 0.08 0.28 5.00
113 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28 5.00
114 INT196626 Binding of DNAH8 and KNG1 1 0.00 0.08 0.27 5.00
115 INT196695 Prkaca Positive_regulation of CFTR 1 0.46 0.13 0.27 5.00
116 INT196637 Binding of DNAH8 and SPANXB1 1 0.00 0.08 0.27 5.00
117 INT280832 Binding of Crh and Ucn3 1 0.16 0.07 0.27 5.00
118 INT196613 Binding of KNG1 and NA 1 0.01 0.08 0.27 5.00
119 INT280850 Binding of Crh and Ucn Positive_regulation of Negative_regulation of Crh 1 0.26 0.06 0.27 5.00
120 INT280822 Jun Regulation of Regulation of Crh 1 0.20 0.08 0.27 5.00
121 INT196616 Binding of NA and SPANXB1 1 0.00 0.08 0.27 5.00
122 INT280805 Positive_regulation of Prkcg Positive_regulation of Avp 1 0.01 0.16 0.26 5.00
123 INT280811 Binding of Crhr1 and Ucn3 1 0.08 0.05 0.25 5.00
124 INT300958 IL1B Positive_regulation of Il6 1 0.04 0.25 0.25 5.00
125 INT121050 Crh Regulation of Localization of Pomc 4 0.43 0.6 0.22 5.00
126 INT196629 PTGER2 Negative_regulation of Gene_expression of NA 1 0.00 0.24 0.22 5.00
127 INT196635 CFTR Positive_regulation of Gene_expression of CCL5 1 0.07 0.44 0.21 5.00
128 INT196610 IFNG Negative_regulation of CFTR 1 0.17 0.21 0.19 5.00
129 INT198382 Binding of AR and SRD5A1 2 0.06 0.84 0.17 5.00
130 INT280846 Crh Positive_regulation of Localization of POMC 1 0.03 0.37 0.16 5.00
131 INT280813 Binding of Avp and S100a8 1 0.00 0.28 0.15 5.00
132 INT196608 TNF Negative_regulation of CFTR 1 0.16 0.11 0.14 5.00
133 INT329118 Binding of KCNA1 and CNTN2 1 0.02 0 0.14 5.00
134 INT319963 Binding of IGFALS and Vcan 1 0.03 2.99 0.13 5.00
135 INT280819 Binding of Creb1 and gr 1 0.01 0 0.13 5.00
136 INT280809 Binding of gr and Rela 1 0.00 0 0.13 5.00
137 INT307627 Binding of BMP1 and CSF2 1 0.01 0.33 0.12 5.00
138 INT345290 AGT Positive_regulation of NOX1 1 0.00 1.11 0.12 5.00
139 INT352497 AGT Positive_regulation of Binding of CRS 1 0.14 0.87 0.11 5.00
140 INT292087 SRC Regulation of IL8 1 0.02 1.43 0.11 5.00
141 INT280836 Gene_expression of Fos Positive_regulation of Crh 1 0.09 0.17 0.1 5.00
142 INT280841 Jun Positive_regulation of Gene_expression of Crh 1 0.35 0.16 0.1 5.00
143 INT262751 Binding of PTCH1 and SMO 1 0.25 1.29 0.1 5.00
144 INT270731 Binding of AGTR1 and ACE 1 0.02 0.67 0.09 5.00
145 INT262758 MRGPRF Positive_regulation of Transcription of NFE2L3 1 0.01 1.25 0.09 5.00
146 INT262754 MRGPRF Positive_regulation of NFE2L3 1 0.01 1.24 0.09 5.00
147 INT308225 Alb Positive_regulation of Binding of EIF4G2 1 0.02 0.33 0.09 5.00
148 INT262755 MRGPRF Positive_regulation of NFE2L2 1 0.18 1.24 0.09 5.00
149 INT196642 IL1B Positive_regulation of Gene_expression of DNAH8 1 0.00 0 0.08 5.00
150 INT196630 TNF Regulation of Gene_expression of NA 1 0.04 0.16 0.08 5.00
151 INT355542 Binding of XRCC3 and BCC1 1 0.00 1.19 0.07 5.00
152 INT345292 Binding of Lcn2 and Havcr1 1 0.00 1.17 0.07 5.00
153 INT196624 TNF Negative_regulation of Transcription of SCNN1G 1 0.02 0.07 0.07 5.00
154 INT345297 Binding of NAGLU and Lcn2 1 0.01 1.24 0.07 5.00
155 INT329121 Binding of LGI1 and ADAM22 1 0.14 0.5 0.06 5.00
156 INT280818 Jun Positive_regulation of Avp 1 0.06 0.23 0.06 5.00
157 INT280834 Negative_regulation of Jun Positive_regulation of Avp 1 0.05 0.23 0.06 5.00
158 INT262781 Birc5 Regulation of TEP1 1 0.00 0.49 0.05 5.00
159 INT262780 Birc5 Regulation of CD163L1 1 0.00 0.49 0.05 5.00
160 INT292089 Binding of KIT and TXK 1 0.02 1.54 0.04 5.00
161 INT292084 Binding of FLT3 and TXK 1 0.02 1.53 0.04 5.00
162 INT262757 SMO Positive_regulation of Regulation of GLI1 1 0.34 0.6 0.04 5.00
163 INT292090 Negative_regulation of Binding of KIT and TXK 1 0.02 1.54 0.04 5.00
164 INT200428 Sdcbp Positive_regulation of Gene_expression of Gfap 1 0.04 0.15 0.04 5.00
165 INT292083 Binding of KDR and TXK 1 0.04 1.52 0.04 5.00
166 INT280843 Binding of Crem and Crh 1 0.03 0.22 0.04 5.00
167 INT292092 Binding of PDGFRB and TXK 1 0.05 1.53 0.04 5.00
168 INT306513 EDN3 Positive_regulation of EDNRB 1 0.14 0.98 0.04 5.00
169 INT280817 Binding of Cdx1 and Crh 1 0.02 0.21 0.04 5.00
170 INT292085 Negative_regulation of Binding of FLT3 and TXK 1 0.02 1.54 0.04 5.00
171 INT306514 EDN1 Positive_regulation of EDNRB 1 0.11 0.98 0.04 5.00
172 INT292094 Binding of FLT4 and TXK 1 0.02 1.53 0.04 5.00
173 INT292095 Negative_regulation of Binding of KDR and TXK 1 0.04 1.53 0.04 5.00
174 INT292080 Binding of FLT1 and TXK 1 0.04 1.47 0.04 5.00
175 INT292079 Negative_regulation of Binding of PDGFRB and TXK 1 0.06 1.54 0.04 5.00
176 INT292086 Negative_regulation of Binding of FLT1 and TXK 1 0.04 1.48 0.04 5.00
177 INT292093 Negative_regulation of Binding of FLT4 and TXK 1 0.03 1.53 0.04 5.00
178 INT345298 NLRP3 Positive_regulation of Localization of Edn1 1 0.01 0.94 0.03 5.00
179 INT196639 Negative_regulation of NA Negative_regulation of Transcription of CFTR 1 0.02 0.63 0.03 5.00
180 INT292081 Binding of EDN1 and NCOR2 1 0.00 0.98 0.03 5.00
181 INT292137 Regulation of Mtor Regulation of Gene_expression of VEGFA 1 0.01 0.75 0 5.00
182 INT292082 MIR1200 Negative_regulation of KDR 1 0.00 1.24 0 5.00
183 INT292088 Binding of AMELX and ANGPT1 1 0.00 0.9 0 5.00
184 INT345287 Binding of SCN10A and RAPGEF5 1 0.01 0.67 0 5.00
185 INT327101 Binding of AREG and EGF 1 0.05 0.35 0 5.00
186 INT270732 DBP Negative_regulation of SHBG 1 0.00 1.08 0 5.00
187 INT292136 Mtor Regulation of Gene_expression of VEGFA 1 0.01 0.75 0 5.00
188 INT280840 Avp Regulation of Localization of Pomc 1 0.02 0.16 0 5.00
189 INT280845 Binding of ELANE and Avp 1 0.06 0 0 5.00
190 INT262750 GLYR1 Positive_regulation of THBS1 1 0.01 0.99 0 5.00
191 INT262759 PIK3CG Positive_regulation of MTOR 1 0.38 0.54 0 5.00
192 INT176131 Binding of AKT1 and PIK3CG 2 0.15 1.08 0 5.00
193 INT292135 Binding of Anpep and Rtn4r 1 0.01 0.91 0 5.00
194 INT280806 Avpr1b Positive_regulation of Localization of Pomc 1 0.19 0.17 0 5.00
195 INT292091 MIR1200 Negative_regulation of PDGFRB 1 0.01 1.24 0 5.00
196 INT334894 Binding of CALCR and ARMC9 1 0.01 0.41 0 5.00
197 INT205121 Binding of CD4 and CD7 1 0.05 0.51 0 5.00
198 INT297615 Binding of TSC1 and HDAC9 1 0.01 0.4 0 5.00
199 INT262752 IGHA1 Positive_regulation of IGKV2D-19 1 0.00 1.39 0 5.00
200 INT354789 Tnc Regulation of HSPG2 1 0.02 1.38 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hyponatremia. They are ordered first by their pain relevance and then by number of times they were reported in Hyponatremia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT214 Localization of AVP 370 0.81 208.51 91.09 100.00
2 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23 100.00
3 INT6129 Positive_regulation of Localization of AVP 63 0.70 30.44 16.64 100.00
4 INT682 Negative_regulation of AVP 97 0.59 50.67 23.91 100.00
5 INT684 Binding of AVP 38 0.48 13.9 8.85 100.00
6 INT106639 Negative_regulation of Negative_regulation of AVPR2 1 0.29 1.58 0.25 100.00
7 INT72746 Localization of Avpr1a 4 0.73 2.54 0.73 100.00
8 INT11300 Positive_regulation of Gene_expression of Avp 24 0.50 10.18 2.69 99.96
9 INT4207 Regulation of Avp 267 0.62 63.72 115.33 99.96
10 INT16870 Negative_regulation of Gsr 27 0.59 10.28 11.81 99.96
11 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41 99.92
12 INT477 Localization of Avp 813 0.81 131.58 300.4 99.92
13 INT21032 Gene_expression of Adh1 23 0.78 22.1 6.14 99.92
14 INT213 Negative_regulation of Localization of AVP 46 0.59 19.78 16.79 99.92
15 INT21631 Positive_regulation of Gene_expression of Adh1 4 0.70 12.56 0.39 99.92
16 INT47514 Localization of Avpr2 7 0.61 4.43 1.24 99.92
17 INT155822 Localization of ADH1A 3 0.78 3.74 0.32 99.92
18 INT28872 Positive_regulation of CSRP1 49 0.70 47.23 11.7 99.92
19 INT179373 Localization of XDH 3 0.20 1.97 0.54 99.92
20 INT262366 Localization of Adh4 1 0.78 1.88 1 99.92
21 INT16432 Positive_regulation of Localization of Lnpep 12 0.32 1.15 5.05 99.90
22 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 99.88
23 INT105569 Binding of IGFALS 13 0.25 17.31 1.36 99.82
24 INT661 Gene_expression of REN 100 0.78 48.21 11.36 99.80
25 INT25539 Regulation of Gene_expression of AVP 9 0.45 2.74 0.89 99.80
26 INT284568 Negative_regulation of Ods 1 0.05 2.51 0.11 99.76
27 INT895 Negative_regulation of Binding of Avp 7 0.55 2.45 1.9 99.74
28 INT16431 Localization of Lnpep 62 0.70 6.28 23.94 99.72
29 INT44550 Positive_regulation of Gene_expression of AVP 38 0.70 22.27 8.62 99.70
30 INT6127 Regulation of Localization of AVP 60 0.62 15.12 20.84 99.68
31 INT685 Regulation of AVP 124 0.62 34.9 39.91 99.66
32 INT10923 Positive_regulation of Lipg 30 0.50 22.87 4.26 99.60
33 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 99.56
34 INT894 Binding of Avp 84 0.48 29.16 29.63 99.48
35 INT5941 Gene_expression of Oxt 164 0.76 22.63 65.47 99.48
36 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43 99.48
37 INT320068 Gene_expression of AVPR2 1 0.65 0.91 0.19 99.46
38 INT21632 Positive_regulation of Adh1 32 0.70 15.67 11.65 99.42
39 INT1261 Localization of Adh1 63 0.81 19.36 16.09 99.36
40 INT73117 Positive_regulation of DNMT3B 20 0.47 10.31 5.31 99.36
41 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 99.34
42 INT2893 Localization of Oxt 219 0.80 28.96 79.43 99.28
43 INT53780 Binding of Avp 19 0.48 6.16 2.55 99.28
44 INT11303 Gene_expression of Avp 116 0.78 39.23 23.88 99.24
45 INT1934 Positive_regulation of Cys1 68 0.68 60.56 10.47 99.12
46 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 99.08
47 INT3579 Localization of Oxt 555 0.81 43.35 292.44 99.00
48 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 98.96
49 INT7470 Positive_regulation of Gene_expression of Avp 37 0.70 19.55 19.96 98.96
50 INT47948 Localization of Alad 1 0.14 1.47 0.07 98.96
51 INT921 Regulation of GH1 172 0.60 52.88 51.04 98.96
52 INT13735 Negative_regulation of Regulation of GH1 14 0.42 4.35 5.39 98.96
53 INT7885 Positive_regulation of Localization of Oxt 160 0.70 14.36 87.7 98.92
54 INT112424 Gene_expression of AVPR1B 6 0.65 1.35 0.16 98.74
55 INT148671 Gene_expression of Aip 26 0.63 24.32 3.91 98.72
56 INT654 Localization of REN 250 0.81 75.12 47.86 98.68
57 INT50490 Regulation of PTGS2 80 0.48 39.51 25.85 98.68
58 INT28055 Positive_regulation of Ces2a 2 0.03 1.3 0.66 98.48
59 INT13743 Regulation of Gene_expression of Avp 30 0.62 6.9 11.66 98.36
60 INT14902 Negative_regulation of XDH 38 0.55 24.19 2.86 98.28
61 INT7886 Regulation of Localization of Avp 146 0.62 14.53 72.99 98.26
62 INT5743 Localization of NA 104 0.59 14.35 35.29 98.20
63 INT4358 Positive_regulation of Localization of Avp 195 0.70 30.79 77.58 98.16
64 INT241787 Negative_regulation of AQP2 1 0.57 1.38 0.03 97.96
65 INT10848 Negative_regulation of Gene_expression of AVP 13 0.59 6.76 2.71 97.88
66 INT5426 Negative_regulation of RTCA 58 0.51 12.34 25.74 97.80
67 INT5939 Regulation of Gene_expression of Oxt 27 0.51 2.84 9.1 97.72
68 INT4336 Negative_regulation of Gene_expression of REN 13 0.58 7.22 1.43 97.66
69 INT241788 Positive_regulation of Gene_expression of AQP2 3 0.67 1.26 0.7 97.60
70 INT5622 Gene_expression of Nppa 101 0.78 49.46 25.31 97.48
71 INT1536 Negative_regulation of NA 244 0.55 52.67 59.79 97.32
72 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 97.16
73 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84 97.04
74 INT31738 Negative_regulation of Regulation of AVP 3 0.37 1.36 0.4 97.00
75 INT100328 Gene_expression of AQP2 6 0.75 2.41 1.21 96.96
76 INT655 Positive_regulation of Localization of REN 86 0.70 32.41 13.56 96.88
77 INT122709 Localization of CYP3A4 16 0.75 5.41 2.38 96.72
78 INT27989 Positive_regulation of Gene_expression of REN 18 0.55 12.69 2.11 96.70
79 INT19511 Localization of Il6 212 0.81 118.17 67.67 96.64
80 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 96.60
81 INT2148 Negative_regulation of Oxt 105 0.59 11.42 57 96.56
82 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 96.52
83 INT252756 Positive_regulation of ABCD1 2 0.05 1.78 0.24 96.52
84 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 96.48
85 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 96.48
86 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43 96.48
87 INT11121 Positive_regulation of NPPA 64 0.70 34.09 11.96 96.44
88 INT11064 Positive_regulation of NPR1 24 0.49 14.63 4.78 96.44
89 INT14442 Localization of GBE1 19 0.31 9.09 5.03 96.40
90 INT4261 Positive_regulation of Localization of Adh1 11 0.61 2.04 3.49 96.40
91 INT38330 Binding of Adh1 4 0.41 3.98 0.3 96.24
92 INT2393 Positive_regulation of Mb 174 0.69 93.59 26.79 96.24
93 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 95.80
94 INT320070 Localization of AVPR2 1 0.72 1.07 0.15 95.64
95 INT177716 Gene_expression of GALNT3 7 0.53 6.91 0.75 95.60
96 INT15156 Positive_regulation of Localization of NPPA 21 0.70 8.61 6.97 95.60
97 INT51474 Binding of Il6 55 0.48 44.99 20.52 95.48
98 INT7132 Localization of NPPA 53 0.81 19.79 10.86 95.40
99 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 95.36
100 INT214706 Gene_expression of Bok 3 0.09 7.22 0.11 95.36
101 INT15509 Negative_regulation of HMBS 14 0.58 13.13 2.78 95.24
102 INT119880 Binding of Usf1 5 0.20 2.55 1.28 95.12
103 INT10536 Gene_expression of Trib3 67 0.66 27.08 21.58 95.08
104 INT10535 Positive_regulation of Gene_expression of Trib3 13 0.59 4.93 3.74 95.08
105 INT131977 Positive_regulation of Localization of Avp 6 0.55 4.9 1.31 94.92
106 INT106638 Negative_regulation of AVPR2 2 0.39 2.05 0.2 94.88
107 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48 94.82
108 INT443 Localization of POMC 1020 0.81 284.52 443.17 94.80
109 INT1756 Negative_regulation of DNAH8 105 0.59 42.73 20.24 94.76
110 INT12564 Localization of Pthlh 23 0.81 4.37 5.82 94.60
111 INT12565 Regulation of Localization of Pthlh 10 0.62 0.71 2.14 94.60
112 INT40962 Localization of Avp 40 0.80 20.5 6.38 94.48
113 INT23174 Gene_expression of NLRP3 51 0.72 35.49 6.47 94.16
114 INT15982 Positive_regulation of NLRP3 25 0.65 23.19 3.57 94.16
115 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 93.76
116 INT660 Negative_regulation of REN 194 0.59 82.06 29.46 93.52
117 INT280772 Binding of Usf2 1 0.13 0.52 0 93.48
118 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 93.40
119 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 93.28
120 INT14764 Negative_regulation of Localization of Nppa 28 0.59 11.29 12.82 93.00
121 INT1721 Negative_regulation of HP 148 0.42 86.82 16.89 92.92
122 INT6637 Positive_regulation of Avpr2 2 0.10 1.02 0.34 92.84
123 INT5617 Localization of Nppa 266 0.81 83.51 83.89 92.68
124 INT10353 Positive_regulation of PGR 34 0.70 21.84 3.28 92.68
125 INT344059 Positive_regulation of Esl1 1 0.04 1.54 0.48 92.68
126 INT344066 Positive_regulation of Binding of PGR 1 0.03 0.63 0.12 92.68
127 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2 92.64
128 INT425 Localization of PRL 455 0.81 189.64 144.8 92.60
129 INT18007 Positive_regulation of C6orf25 23 0.66 14.98 1.95 92.56
130 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 92.52
131 INT64538 Binding of TNNI3 17 0.48 11.65 1.83 92.48
132 INT68496 Binding of PGR 26 0.48 16.36 2.09 92.20
133 INT19805 Negative_regulation of Avp 18 0.59 4.57 5.87 91.96
134 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 91.92
135 INT9552 Positive_regulation of TNNI3 209 0.70 128.67 19.15 91.84
136 INT9660 Regulation of TNF 363 0.62 312.94 139.99 91.80
137 INT177717 Positive_regulation of Gene_expression of GALNT3 2 0.03 2.84 0.18 91.56
138 INT177594 Binding of TRGV9 7 0.14 3.28 0.33 91.52
139 INT209189 Binding of AVPR1A 5 0.29 1.94 0.43 91.52
140 INT177599 Binding of AVPR1B 2 0.04 0.49 0.04 91.52
141 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 91.32
142 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 91.08
143 INT99966 Negative_regulation of Positive_regulation of NARFL 13 0.37 13.32 0.98 91.00
144 INT41314 Gene_expression of GGTLC1 9 0.59 5.61 1.79 90.88
145 INT3911 Gene_expression of TNFAIP1 29 0.65 21.68 1.85 90.28
146 INT8336 Transcription of Gnrh1 22 0.71 4.37 4.69 90.04
147 INT241790 Negative_regulation of AVPR1A 6 0.57 4.62 0.35 89.76
148 INT91045 Negative_regulation of ESRRB 2 0.35 0.45 0.18 89.36
149 INT106636 Binding of PRKCA 7 0.28 3.06 1.93 89.04
150 INT106632 Binding of GRK5 1 0.31 0.82 0.19 89.04
151 INT5620 Positive_regulation of Localization of Nppa 105 0.70 30.23 36.45 88.56
152 INT1438 Localization of Pomc 360 0.81 101.26 116.47 88.44
153 INT34590 Gene_expression of ALPP 199 0.75 89.85 15.1 88.40
154 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 88.32
155 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 88.16
156 INT200585 Negative_regulation of Binding of AVP 3 0.39 0.61 0.14 88.04
157 INT119606 Regulation of Gene_expression of LEP 17 0.45 17.96 3.75 87.56
158 INT10879 Positive_regulation of Avp 39 0.65 14.01 8.76 87.44
159 INT344063 Binding of Esl1 1 0.04 3.16 0.8 87.28
160 INT8205 Negative_regulation of Nppa 77 0.59 26.43 25.72 86.96
161 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 86.80
162 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 86.76
163 INT170156 Phosphorylation of MMP12 3 0.68 0.83 0.75 86.64
164 INT504 Gene_expression of GPT 42 0.75 27.54 3.99 86.64
165 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 86.60
166 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22 86.60
167 INT16357 Negative_regulation of NPPA 23 0.58 12.37 2.98 86.56
168 INT26972 Negative_regulation of Tenc1 57 0.57 56.71 16.87 86.40
169 INT812 Localization of INS 1026 0.81 515.6 145.31 86.36
170 INT184694 Gene_expression of Usf1 10 0.55 4.27 0.72 86.36
171 INT4679 Negative_regulation of RAPGEF5 55 0.57 47.51 4.55 86.28
172 INT280793 Gene_expression of Usf2 1 0.23 1.4 0 86.16
173 INT262770 Binding of SLC25A16 1 0.05 1.04 0 85.80
174 INT146594 Negative_regulation of Gene_expression of LEP 25 0.42 18.88 5.71 85.40
175 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 85.32
176 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 85.16
177 INT5361 Positive_regulation of CPM 4 0.60 1.61 0.09 85.04
178 INT196690 Regulation of SEC23B 1 0.01 2.88 0.43 84.92
179 INT111869 Protein_catabolism of AVP 3 0.64 0.63 0.42 84.52
180 INT280802 Gene_expression of Bhlha15 1 0.06 0.5 0 84.52
181 INT138802 Gene_expression of CFTR 36 0.70 18.8 7.02 84.48
182 INT196673 Regulation of Gene_expression of CFTR 1 0.36 0.62 0.08 84.48
183 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 84.40
184 INT58161 Positive_regulation of Transcription of Avp 2 0.37 0.58 0.31 84.08
185 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 84.04
186 INT37652 Positive_regulation of Pgr 29 0.59 9.09 4.67 83.84
187 INT344060 Gene_expression of Esl1 1 0.06 3.65 1.09 83.84
188 INT140949 Positive_regulation of Positive_regulation of Pgr 4 0.59 1.23 0.42 83.84
189 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64 83.76
190 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 83.68
191 INT619 Positive_regulation of Positive_regulation of Prl 116 0.70 22.69 45.06 83.68
192 INT35209 Positive_regulation of Negative_regulation of Gnrhr 5 0.48 1.38 1.53 83.68
193 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 83.52
194 INT58165 Transcription of Avp 12 0.69 0.83 0.66 83.48
195 INT320067 Localization of AVPR1A 1 0.73 1.78 0.27 83.44
196 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 82.28
197 INT19 Regulation of Gnrhr 131 0.62 36.4 55.66 81.92
198 INT75908 Regulation of LEP 77 0.60 60.16 15.19 81.64
199 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 81.40
200 INT1361 Negative_regulation of Gnrhr 118 0.58 57.77 35.54 81.36
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