D:Hypoventilation

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Disease Term
Synonyms Hypoventilations
Documents 416
Hot Single Events 40
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hypoventilation. They are ordered first by their relevance to Hypoventilation and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT84867 Ptger1 Negative_regulation of SETD2 1 0.00 1.09 0.11 80.12
2 INT317833 Nlrp3 Positive_regulation of Localization of Il1 1 0.06 1.38 0.26 55.92
3 INT345966 Binding of Arid1a and al44 1 0.00 1.56 0.05 52.52
4 INT345965 Binding of Lep and al44 1 0.01 1.43 0.05 52.52
5 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9 5.00
6 INT317836 Binding of Fibp and Pycard 1 0.00 2.68 0.98 5.00
7 INT317832 Binding of Mefv and Il1 1 0.03 3.89 0.7 5.00
8 INT340212 Csf2 Positive_regulation of Pttg1ip 1 0.02 0.46 0.49 5.00
9 INT317834 Binding of Pstpip1 and Il1 1 0.00 2.03 0.48 5.00
10 INT278379 Binding of Pstpip1 and Mefv 3 0.03 2.02 0.48 5.00
11 INT317835 Nlrp3 Positive_regulation of Il18 1 0.08 1.49 0.31 5.00
12 INT317831 Binding of Mefv and Nlrx1 1 0.00 1.77 0.2 5.00
13 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19 5.00
14 INT217665 ADIPOQ Positive_regulation of INS 2 0.06 1.8 0.19 5.00
15 INT217667 LEP Negative_regulation of Localization of INS 1 0.15 1.18 0.14 5.00
16 INT217664 LEP Negative_regulation of INS 1 0.15 1.18 0.14 5.00
17 INT217666 ADIPOQ Regulation of Gene_expression of INS 1 0.03 1.99 0.05 5.00
18 INT313273 Binding of GRIN1 and MAP2 1 0.16 0.79 0.04 5.00
19 INT313271 Binding of GRIN1 and GRIN2B 1 0.24 0.06 0 5.00
20 INT264683 Binding of VAPB and ALS2 1 0.29 1.1 0 5.00
21 INT256210 NPPB Regulation of PVR 1 0.24 1.14 0 5.00
22 INT221910 Binding of SRI and COPD 1 0.01 1.27 0 5.00
23 INT227399 Binding of D5Mit424 and Alms1 1 0.01 0.71 0 5.00
24 INT313272 Binding of DLG4 and GRIN1 1 0.09 0.06 0 5.00
25 INT264679 IGFALS Positive_regulation of CTSC 1 0.02 1.68 0 5.00
26 INT256209 AVP Regulation of PVR 1 0.06 0.99 0 5.00
27 INT264678 Binding of SETX and KRT20 1 0.00 2.17 0 5.00
28 INT256211 NPPB Regulation of PDAP1 1 0.28 1.14 0 5.00
29 INT227398 Binding of H2afy and Alms1 1 0.01 1.42 0 5.00
30 INT264682 Binding of VAPB and SETX 1 0.28 1.09 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hypoventilation. They are ordered first by their pain relevance and then by number of times they were reported in Hypoventilation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT340200 Negative_regulation of Smyd5 1 0.07 1.1 0.43 100.00
2 INT9199 Positive_regulation of CEBPZ 111 0.67 30.99 28.45 99.40
3 INT22117 Positive_regulation of Negative_regulation of Cms1 1 0.39 1.31 0.19 98.48
4 INT22118 Negative_regulation of Cms1 6 0.38 4.02 0.78 98.48
5 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 98.44
6 INT340209 Negative_regulation of Frg1 1 0.01 0.52 0.6 97.88
7 INT275594 Gene_expression of DYNC1I1 4 0.04 11.7 0.09 97.28
8 INT20612 Positive_regulation of Asap1 36 0.68 24.35 6.06 96.92
9 INT31989 Binding of SOD1 43 0.47 19.38 2.55 95.52
10 INT1893 Localization of Gh 1041 0.79 340.23 256.58 94.08
11 INT50311 Binding of Htas2 9 0.47 1.19 4.91 91.44
12 INT35349 Gene_expression of CENPJ 52 0.57 25.36 2.54 91.04
13 INT16395 Gene_expression of CEBPZ 30 0.57 11.02 6.66 90.84
14 INT37168 Positive_regulation of APCS 22 0.67 9.61 4.59 90.36
15 INT25607 Binding of Il1 82 0.47 64.4 23.9 88.16
16 INT70970 Binding of COPD 144 0.42 180.34 18.29 87.80
17 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41 87.76
18 INT17399 Positive_regulation of Positive_regulation of REN 13 0.69 7.05 1.9 87.76
19 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21 87.56
20 INT271631 Negative_regulation of Localization of Grin1 2 0.32 0.58 0.52 87.56
21 INT16624 Localization of Grin1 38 0.79 8.46 17.15 87.08
22 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 86.88
23 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 86.56
24 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 86.48
25 INT3127 Gene_expression of SRI 38 0.68 26.29 3.82 85.96
26 INT124438 Regulation of Gene_expression of Slc6a4 9 0.62 3.5 2.97 82.52
27 INT39212 Binding of Ttr 14 0.48 9.62 2.31 82.16
28 INT62127 Localization of SRI 12 0.45 10.21 1.54 82.12
29 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 81.88
30 INT47044 Positive_regulation of ORM1 5 0.68 0.58 4.46 81.88
31 INT340203 Regulation of Smyd5 1 0.07 1.5 1.34 81.80
32 INT125312 Positive_regulation of COPD 134 0.59 162.55 20.27 81.60
33 INT28326 Positive_regulation of Negative_regulation of Oprl1 6 0.44 2.01 3.78 81.56
34 INT4637 Binding of Adarb1 132 0.41 14.48 67.76 81.12
35 INT1335 Negative_regulation of Oprl1 123 0.59 18.02 77.13 81.04
36 INT20611 Gene_expression of Asap1 55 0.65 23.71 14.62 80.56
37 INT242321 Negative_regulation of Gene_expression of Asap1 1 0.20 1.96 0 80.56
38 INT2893 Localization of Oxt 219 0.80 28.96 79.43 80.32
39 INT10340 Regulation of Localization of Oxt 30 0.60 2.55 14.3 80.32
40 INT91775 Gene_expression of Slc6a4 102 0.78 26.45 28.23 80.28
41 INT24904 Negative_regulation of PAPPA 13 0.57 9.93 2.74 79.48
42 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 78.96
43 INT19775 Localization of Il1 183 0.78 145.5 50.91 78.32
44 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 77.00
45 INT144057 Transcription of SRI 5 0.67 7.94 2.6 75.60
46 INT211758 Binding of Mmd 1 0.13 3.09 0.1 75.44
47 INT27188 Negative_regulation of Tcn2 5 0.18 1.33 0.83 73.96
48 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 73.84
49 INT169251 Gene_expression of Phox2b 9 0.70 3.88 1.17 73.84
50 INT177683 Negative_regulation of Gene_expression of CENPJ 5 0.32 4.27 0.03 73.20
51 INT213535 Transcription of Phox2b 3 0.62 2.69 0.49 72.24
52 INT60436 Negative_regulation of COPD 76 0.37 84.22 9.08 71.92
53 INT125384 Positive_regulation of Pain1 23 0.49 17.1 14.83 71.76
54 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 71.44
55 INT16396 Negative_regulation of CEBPZ 76 0.48 30.03 21.6 70.96
56 INT275343 Positive_regulation of Binding of COPD 2 0.42 3.04 0.33 69.24
57 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 68.88
58 INT25796 Regulation of Gene_expression of Adarb1 6 0.26 2.77 4.3 68.60
59 INT150867 Regulation of COPD 54 0.48 71.38 8.8 67.68
60 INT6165 Gene_expression of Adarb1 85 0.58 18.39 51.03 67.56
61 INT1530 Regulation of Gh 382 0.61 115.96 112.47 66.24
62 INT62400 Positive_regulation of Localization of Il1 34 0.67 35.53 7.96 65.88
63 INT91338 Binding of Lep 31 0.48 26.86 5.39 65.68
64 INT345957 Positive_regulation of Binding of Lep 2 0.38 2.03 0.6 65.68
65 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 65.64
66 INT213471 Positive_regulation of Localization of Lep 4 0.48 2.65 0.74 60.68
67 INT163581 Localization of Lep 27 0.79 18.99 4.08 60.20
68 INT14572 Binding of INS 205 0.48 175.43 13.38 59.68
69 INT75907 Binding of LEP 53 0.46 46.65 8.44 59.68
70 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91 58.32
71 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95 57.16
72 INT10498 Positive_regulation of Tcn2 7 0.19 1.76 1.87 56.84
73 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12 53.84
74 INT36221 Positive_regulation of Nlrp3 25 0.68 19.7 4.5 53.76
75 INT219136 Positive_regulation of Positive_regulation of Nlrp3 3 0.49 2.61 0.58 53.76
76 INT203637 Binding of CD2AP 1 0.04 0.57 0.03 45.96
77 INT340202 Gene_expression of Frg1 1 0.01 0.13 0.29 45.92
78 INT189927 Gene_expression of Arid1a 8 0.59 9.03 0.43 45.68
79 INT345950 Positive_regulation of Gene_expression of Arid1a 1 0.12 3.63 0.37 45.68
80 INT174054 Positive_regulation of Gene_expression of Lep 25 0.69 21.3 3.72 44.32
81 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77 43.68
82 INT146594 Negative_regulation of Gene_expression of LEP 25 0.42 18.88 5.71 43.68
83 INT117855 Negative_regulation of Ghrl 29 0.57 17.52 5 43.68
84 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 43.28
85 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22 43.28
86 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17 43.28
87 INT107291 Positive_regulation of Ghrl 58 0.67 44.6 9.68 42.56
88 INT132317 Positive_regulation of Gene_expression of Ghrl 20 0.49 21 3.57 42.56
89 INT61893 Gene_expression of Ghrl 125 0.75 71.49 15.14 42.16
90 INT35132 Gene_expression of PDAP1 18 0.52 9.05 1.5 41.44
91 INT101482 Negative_regulation of Lep 53 0.54 33.59 5.65 41.04
92 INT167270 Negative_regulation of Gene_expression of Lep 13 0.55 5.48 1.19 41.04
93 INT74726 Negative_regulation of Slc6a4 61 0.59 21.01 27.84 39.80
94 INT22429 Positive_regulation of PDAP1 34 0.61 22.58 2.91 38.72
95 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 36.16
96 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42 36.16
97 INT321985 Gene_expression of Etan1 1 0.01 1.5 0.28 35.20
98 INT333278 Negative_regulation of Transcription of Slc6a4 2 0.37 0.56 0.36 33.52
99 INT103021 Transcription of Slc6a4 16 0.70 3.93 3.77 33.24
100 INT94827 Gene_expression of HBS1L 24 0.67 26.11 1.61 32.92
101 INT41893 Negative_regulation of HBS1L 16 0.23 8.98 1.19 32.92
102 INT203636 Positive_regulation of CD2AP 4 0.13 1.27 0.28 32.36
103 INT7362 Gene_expression of Sst 185 0.78 41.73 111.37 31.04
104 INT49110 Regulation of Grip2 46 0.61 13.57 30.87 30.64
105 INT797 Regulation of Penk 812 0.62 111.13 542.24 30.40
106 INT340195 Regulation of Pttg1ip 1 0.47 4.53 1.4 30.32
107 INT202176 Gene_expression of MIXL1 4 0.65 1.5 0.29 28.08
108 INT10847 Gene_expression of LAMC2 39 0.75 27 12.09 26.56
109 INT119346 Positive_regulation of PTGIR 9 0.58 6.2 1.61 26.24
110 INT6042 Binding of Oprm1 248 0.48 31.77 154.34 25.00
111 INT95342 Gene_expression of GRIN2B 21 0.75 4.99 9.32 25.00
112 INT20470 Positive_regulation of Acsl1 5 0.40 3.76 1.03 25.00
113 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93 24.36
114 INT211756 Phosphorylation of Mmd 1 0.17 1.44 0.03 23.68
115 INT264580 Binding of Grhl2 1 0.05 0.35 0.08 23.32
116 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 22.16
117 INT6214 Negative_regulation of Adarb1 123 0.50 26.39 89.57 18.56
118 INT11246 Binding of Grin1 65 0.48 14.53 36.93 16.92
119 INT1705 Gene_expression of pCA 126 0.65 88.65 34.81 14.96
120 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69 11.52
121 INT42425 Gene_expression of Mmd 2 0.75 1.68 0.91 10.32
122 INT179214 Binding of AMIGO2 4 0.32 3.9 0.35 7.72
123 INT61784 Positive_regulation of CENPJ 27 0.51 11.46 2.28 6.64
124 INT340186 Negative_regulation of Pttg1ip 1 0.33 1.78 2.65 5.44
125 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
126 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
127 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
128 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
129 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
130 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
131 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 5.00
132 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
133 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 5.00
134 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 5.00
135 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 5.00
136 INT768 Positive_regulation of Oprl1 179 0.70 40.05 156.93 5.00
137 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
138 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61 5.00
139 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
140 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
141 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
142 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
143 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
144 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
145 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
146 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
147 INT114 Binding of Oprl1 139 0.48 23 103.35 5.00
148 INT214 Localization of AVP 370 0.81 208.51 91.09 5.00
149 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 5.00
150 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 5.00
151 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
152 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05 5.00
153 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 5.00
154 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 5.00
155 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
156 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 5.00
157 INT251 Regulation of INS 398 0.62 232.47 55.04 5.00
158 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32 5.00
159 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 5.00
160 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
161 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 5.00
162 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24 5.00
163 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
164 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
165 INT173693 Localization of Gopc 249 0.65 70.49 38.81 5.00
166 INT11439 Positive_regulation of Csf2 105 0.69 62.63 37.77 5.00
167 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 5.00
168 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 5.00
169 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23 5.00
170 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23 5.00
171 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38 5.00
172 INT47710 Negative_regulation of GRIN1 71 0.57 25.57 34.24 5.00
173 INT84825 Gene_expression of CD36 121 0.78 43.73 33.23 5.00
174 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 5.00
175 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
176 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 5.00
177 INT17886 Negative_regulation of Il1 95 0.57 70.91 31.25 5.00
178 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 5.00
179 INT12502 Regulation of Adarb1 50 0.53 7.58 30.01 5.00
180 INT67912 Gene_expression of GRIN1 75 0.77 28.99 29.28 5.00
181 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18 5.00
182 INT6855 Binding of NCOR2 71 0.41 15.64 28.96 5.00
183 INT1616 Regulation of Gad1 46 0.61 10.2 28.64 5.00
184 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 5.00
185 INT56524 Gene_expression of Grip2 67 0.74 14.77 26.23 5.00
186 INT48832 Positive_regulation of Grip2 48 0.69 12.13 25.99 5.00
187 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 5.00
188 INT27933 Gene_expression of NCOR2 65 0.72 31.35 24.23 5.00
189 INT35716 Positive_regulation of NCOR2 45 0.60 18 23.54 5.00
190 INT1704 Positive_regulation of PCa 68 0.59 34.92 23.36 5.00
191 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03 5.00
192 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42 5.00
193 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
194 INT24569 Negative_regulation of Pain1 26 0.41 21.82 21.08 5.00
195 INT1703 Regulation of PCa 52 0.52 23.65 20.6 5.00
196 INT31874 Negative_regulation of Gene_expression of Abat 31 0.42 12.22 20.31 5.00
197 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 5.00
198 INT20129 Regulation of Il1 53 0.53 44.14 19.89 5.00
199 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 5.00
200 INT75742 Binding of RLS 86 0.42 95.27 19.04 5.00
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