D:Idiopathic Hypersomnolence

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms CNS HYPERSOMNOLENCE IDIOPATHIC, Cns Hypersomnolences Idiopathic, Hypersomnia Idiopathic, Hypersomnias Idiopathic, Hypersomnolence Cns Idiopathic, Hypersomnolence Idiopathic Cns, Hypersomnolences Idiopathic, HYPERSOMNOLENCES IDIOPATHIC CNS, Idiopathic Central Nervous System Hypersomnolence, IDIOPATHIC CNS HYPERSOMNOLENCE, Idiopathic Cns Hypersomnolences
Documents 14
Hot Single Events 19
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Idiopathic Hypersomnolence. They are ordered first by their relevance to Idiopathic Hypersomnolence and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT213608 Binding of PER2 and CLOCK 1 0.22 0.65 0.04 86.96
2 INT213607 Binding of CSNK1D and CLOCK 1 0.27 0.65 0.04 85.44
3 INT336576 Binding of HCRTR1 and IGHG3 1 0.01 5.01 0 60.04
4 INT274353 DST Regulation of Gopc 1 0.00 0 0.17 5.00
5 INT213606 CLOCK Regulation of Gene_expression of PROK2 1 0.20 0.3 0 5.00
6 INT336480 Binding of Pln and RLS 1 0.02 0.34 0 5.00
7 INT336574 Binding of CD40LG and HCRTR1 1 0.05 0.1 0 5.00
8 INT213609 CLOCK Regulation of PROK2 1 0.20 0.3 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Idiopathic Hypersomnolence. They are ordered first by their pain relevance and then by number of times they were reported in Idiopathic Hypersomnolence. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT130105 Positive_regulation of HCRTR1 3 0.27 6.47 0.38 99.76
2 INT148884 Negative_regulation of HCRTR1 7 0.23 7.23 0.53 99.72
3 INT148886 Negative_regulation of Gene_expression of HCRTR1 2 0.23 3.42 0.05 99.72
4 INT106057 Negative_regulation of Hcrt 27 0.57 15.5 3.47 99.72
5 INT106055 Negative_regulation of Gene_expression of Hcrt 15 0.46 5.64 2.09 99.72
6 INT148883 Gene_expression of HCRTR1 8 0.36 24.82 1.35 99.48
7 INT106056 Gene_expression of Hcrt 77 0.76 35.35 8.16 99.16
8 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 97.60
9 INT336583 Positive_regulation of Gene_expression of HCRTR1 1 0.27 3.25 0.26 97.24
10 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 97.24
11 INT83451 Positive_regulation of Gene_expression of CD40LG 26 0.60 22.81 6.25 97.24
12 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 96.92
13 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 96.08
14 INT336580 Binding of HCRTR1 1 0.20 3.67 0.13 94.64
15 INT148885 Regulation of HCRTR1 2 0.29 3.41 0.14 91.44
16 INT336581 Regulation of Gene_expression of HCRTR1 1 0.24 0.71 0 91.44
17 INT336582 Positive_regulation of Binding of HCRTR1 1 0.27 0.84 0 87.32
18 INT296914 Regulation of Pln 2 0.19 3.08 1.23 84.32
19 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 83.44
20 INT54924 Gene_expression of RLS 67 0.62 83.2 14.25 79.52
21 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 76.80
22 INT19432 Positive_regulation of Gene_expression of CD79A 14 0.45 13.49 1.49 74.76
23 INT336579 Regulation of Regulation of HCRTR1 1 0.15 1.94 0.05 73.52
24 INT102658 Negative_regulation of Gene_expression of CSF2 42 0.50 38.63 8.32 71.92
25 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 71.92
26 INT71633 Negative_regulation of SLC6A3 25 0.59 10.5 10.69 61.76
27 INT267806 Negative_regulation of Pln 8 0.40 4.01 1.63 57.56
28 INT695 Binding of POMC 304 0.48 56.66 126.85 56.32
29 INT27536 Gene_expression of Caf 4 0.52 0.41 1.13 17.36
30 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 5.00
31 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28 5.00
32 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 5.00
33 INT7528 Regulation of OPRM1 100 0.62 20.63 80.57 5.00
34 INT2416 Negative_regulation of MAOA 92 0.59 42.24 36.5 5.00
35 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23 5.00
36 INT169180 Binding of SNRNP70 204 0.47 119.1 29.3 5.00
37 INT20003 Gene_expression of Scn2a1 125 0.71 8.78 23.94 5.00
38 INT682 Negative_regulation of AVP 97 0.59 50.67 23.91 5.00
39 INT44954 Gene_expression of APP 191 0.78 105.86 23.9 5.00
40 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 5.00
41 INT142735 Regulation of RLS 33 0.53 45.83 11.35 5.00
42 INT67101 Gene_expression of DST 47 0.54 25.92 9.59 5.00
43 INT147452 Gene_expression of ADCYAP1 14 0.77 12.54 9.28 5.00
44 INT54368 Positive_regulation of VTA1 13 0.59 3.81 8.13 5.00
45 INT7813 Regulation of SRI 25 0.61 6.18 8.13 5.00
46 INT121815 Regulation of Positive_regulation of OPRM1 7 0.62 0.75 7.36 5.00
47 INT18340 Gene_expression of CRX 16 0.22 13.85 7.13 5.00
48 INT122896 Negative_regulation of TH 23 0.57 9.27 6.88 5.00
49 INT17674 Localization of Scn2a1 32 0.61 1.73 6.79 5.00
50 INT84965 Gene_expression of MAOA 15 0.75 6.9 6.06 5.00
51 INT52512 Positive_regulation of SLC43A3 21 0.41 5.39 5.27 5.00
52 INT96504 Negative_regulation of SLC18A2 5 0.36 2.07 4.62 5.00
53 INT34624 Negative_regulation of REM1 22 0.38 9.25 4.22 5.00
54 INT3127 Gene_expression of SRI 38 0.68 26.29 3.82 5.00
55 INT183560 Binding of GABRB3 12 0.23 2.59 3.77 5.00
56 INT232667 Binding of Pd 17 0.16 20.76 3.58 5.00
57 INT117117 Positive_regulation of REM1 12 0.40 10.1 3.33 5.00
58 INT178457 Positive_regulation of LIFR 12 0.56 3.98 2.9 5.00
59 INT54370 Negative_regulation of VTA1 5 0.50 2.06 2.77 5.00
60 INT244283 Negative_regulation of Gene_expression of MAOA 2 0.27 1.7 2.5 5.00
61 INT229111 Localization of SLC6A3 5 0.68 1.12 2.48 5.00
62 INT122656 Gene_expression of MTNR1A 21 0.75 6.37 2.46 5.00
63 INT44880 Gene_expression of REM1 21 0.30 5.3 2.43 5.00
64 INT80733 Binding of Scn2a1 11 0.30 1.09 2.3 5.00
65 INT56084 Negative_regulation of SLC43A3 11 0.39 5.39 2.27 5.00
66 INT81154 Gene_expression of HCRT 10 0.75 5.32 2.22 5.00
67 INT53998 Positive_regulation of MAOB 8 0.61 1.22 2 5.00
68 INT258135 Gene_expression of CARTPT 3 0.40 5.25 1.88 5.00
69 INT80032 Gene_expression of NPSR1 3 0.75 5.06 1.75 5.00
70 INT62127 Localization of SRI 12 0.45 10.21 1.54 5.00
71 INT7812 Negative_regulation of SRI 10 0.59 4.28 1.46 5.00
72 INT244284 Binding of SLC18A2 1 0.23 1.87 1.34 5.00
73 INT47027 Positive_regulation of BCHE 6 0.50 2.32 1.09 5.00
74 INT271160 Negative_regulation of SYNE1 1 0.00 0.67 0.81 5.00
75 INT99281 Negative_regulation of HCRT 3 0.57 2.26 0.71 5.00
76 INT213617 Gene_expression of PDE4D 3 0.53 1.98 0.62 5.00
77 INT146563 Gene_expression of PROK2 15 0.75 4.12 0.61 5.00
78 INT310648 Negative_regulation of Negative_regulation of BCHE 2 0.27 1.79 0.59 5.00
79 INT213618 Binding of NPSR1 4 0.35 1.47 0.53 5.00
80 INT267804 Gene_expression of Pln 4 0.47 1.45 0.51 5.00
81 INT274343 Localization of Mt1 1 0.11 0.84 0.48 5.00
82 INT271161 Negative_regulation of Negative_regulation of SYNE1 1 0.00 0.24 0.47 5.00
83 INT274342 Gene_expression of Epha1 1 0.01 0 0.46 5.00
84 INT274341 Positive_regulation of Gene_expression of Epha1 1 0.01 0 0.46 5.00
85 INT267805 Binding of Pln 3 0.33 0.8 0.4 5.00
86 INT258092 Regulation of Gene_expression of Hcrt 2 0.44 2.6 0.29 5.00
87 INT295943 Negative_regulation of MTNR1A 4 0.21 2.66 0.24 5.00
88 INT213613 Localization of NPS 2 0.62 1.11 0.23 5.00
89 INT213615 Localization of NPSR1 2 0.73 0.61 0.17 5.00
90 INT175737 Gene_expression of PER2 4 0.68 0.3 0.16 5.00
91 INT331573 Regulation of Localization of SRI 1 0.23 0.46 0.11 5.00
92 INT296126 Negative_regulation of Gene_expression of MTNR1A 2 0.21 0.77 0.11 5.00
93 INT213614 Negative_regulation of LRP1B 1 0.32 0.4 0.08 5.00
94 INT213612 Negative_regulation of FHIT 1 0.24 0.4 0.08 5.00
95 INT177537 Negative_regulation of CSF3R 1 0.17 1.64 0.05 5.00
96 INT336478 Positive_regulation of Pln 1 0.35 0.13 0 5.00
97 INT157242 Localization of PER2 2 0.68 0.3 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox