D:Ileitis

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Disease Term
Synonyms None
Documents 130
Hot Single Events 47
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Ileitis. They are ordered first by their relevance to Ileitis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT342993 PHEX Regulation of Protein_catabolism of SFTPA1 1 0.00 2.84 1.58 91.44
2 INT238641 Binding of TNF and Ifx 1 0.07 0.86 0.84 74.04
3 INT238642 Binding of TNF and Ada 1 0.03 0.86 0.84 74.04
4 INT342982 HCL1 Positive_regulation of SFTPA1 1 0.00 0.71 0.84 70.84
5 INT348175 Binding of NIDDM1 and PTPN22 1 0.01 2.36 0.99 70.64
6 INT342991 HCL1 Positive_regulation of CALCA 1 0.03 0.71 0.84 70.56
7 INT187222 Binding of Vip and Vipr2 2 0.19 1.82 0.56 67.84
8 INT342990 TRPV1 Positive_regulation of Gene_expression of SFTPA1 1 0.06 1.44 1.26 60.84
9 INT126934 Ltb4r Positive_regulation of Positive_regulation of Trpv1 1 0.05 0 0 50.00
10 INT199031 Binding of ALB and F2 1 0.05 1.78 0.08 37.76
11 INT227418 Binding of DLAT and Pdc 1 0.05 1.01 0.07 28.32
12 INT342980 TRPV1 Negative_regulation of HCL1 Positive_regulation of PTAFR 1 0.03 0.07 0.48 14.68
13 INT342983 HCL1 Positive_regulation of PTAFR 1 0.03 0.07 0.47 14.68
14 INT348173 Binding of HLA-B and IL23R 1 0.15 0.92 0.49 13.76
15 INT348177 Binding of HLA-B and ERAP1 1 0.14 0.92 0.49 13.20
16 INT299113 Binding of INPP5K and GOPC 1 0.18 2.69 0.19 9.28
17 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27 5.00
18 INT342979 HCL1 Positive_regulation of TRPV1 Positive_regulation of Localization of SFTPA1 1 0.00 0.54 1.31 5.00
19 INT342988 HCL1 Positive_regulation of TRPV1 1 0.04 1.15 1.21 5.00
20 INT342986 PTAFR Positive_regulation of Gene_expression of IL6 1 0.14 0.39 0.84 5.00
21 INT342999 IL6 Positive_regulation of Gene_expression of HIST2H2AA3 1 0.00 0.4 0.83 5.00
22 INT342992 Negative_regulation of PTAFR Negative_regulation of Gene_expression of HIST2H2AA3 1 0.01 0.4 0.78 5.00
23 INT348174 Binding of STAT3 and IL23R 1 0.40 1.9 0.76 5.00
24 INT342989 IL8 Regulation of SFTPA1 1 0.02 0.38 0.6 5.00
25 INT342981 PTAFR Regulation of SFTPA1 1 0.03 0.38 0.6 5.00
26 INT252634 Binding of TNF and Tnfrsf1a 4 0.02 2.4 0.46 5.00
27 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46 5.00
28 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45 5.00
29 INT342987 TRPV1 Positive_regulation of Localization of PTAFR 1 0.33 0.84 0.43 5.00
30 INT342998 DUOX1 Positive_regulation of ROS1 1 0.23 0.25 0.43 5.00
31 INT342985 IL8 Positive_regulation of PPBP 1 0.02 0.66 0.3 5.00
32 INT342997 PTAFR Positive_regulation of Gene_expression of HIST2H2AA3 1 0.01 0.61 0.24 5.00
33 INT348364 PROC Negative_regulation of TNF 1 0.01 0.89 0.23 5.00
34 INT342994 IL1B Positive_regulation of Gene_expression of PTAFR 1 0.09 0.39 0.22 5.00
35 INT277995 TNF Positive_regulation of Gene_expression of Tnfrsf1a 1 0.03 1.48 0.22 5.00
36 INT283520 Binding of DLAT and Pain1 1 0.27 0.65 0.22 5.00
37 INT277996 TNF Positive_regulation of Tnfrsf1a 1 0.03 1.48 0.22 5.00
38 INT348363 PCTP Positive_regulation of PROC 1 0.01 0.41 0.2 5.00
39 INT348372 Binding of PROC and Stard10 1 0.01 0.41 0.2 5.00
40 INT288006 Binding of CD28 and LRRC23 1 0.02 0.54 0.19 5.00
41 INT227400 Binding of DLAT and HCC 1 0.01 2.82 0.11 5.00
42 INT283460 Binding of CTLA4 and DLAT 1 0.06 3.14 0.09 5.00
43 INT283521 PREB Regulation of Fam89b 1 0.00 1.08 0.07 5.00
44 INT348365 Binding of PROC and TNF 1 0.00 0.19 0.05 5.00
45 INT283464 Binding of CD4 and DLAT 1 0.07 0.69 0.04 5.00
46 INT288007 Binding of CD28 and CD40 1 0.05 0.51 0.03 5.00
47 INT283463 Binding of DLAT and GAGE4 1 0.00 1.1 0.03 5.00
48 INT348362 Binding of C2 and Positive_regulation of Localization of PLA2G4A 1 0.02 0.37 0.03 5.00
49 INT229098 Binding of TP53 and IER3 1 0.01 1.47 0.03 5.00
50 INT283462 Binding of DLAT and HLA-DRB1 1 0.07 1.06 0.03 5.00
51 INT288008 Binding of CD40 and LRRC23 1 0.02 0.45 0 5.00
52 INT283461 Binding of IL2 and SLC4A2 1 0.01 0.98 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Ileitis. They are ordered first by their pain relevance and then by number of times they were reported in Ileitis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT8707 Localization of LILRB1 2 0.60 1.5 1.5 100.00
2 INT222742 Regulation of S100A12 4 0.53 12.09 3.03 99.48
3 INT1761 Positive_regulation of PTGER2 135 0.49 90.17 26.26 99.32
4 INT250993 Gene_expression of FANCE 8 0.48 4.41 0.27 98.72
5 INT299114 Localization of FANCE 5 0.53 3.37 1.49 98.08
6 INT131421 Localization of INPP5K 9 0.74 4.3 0.59 97.92
7 INT15157 Gene_expression of INPP5K 30 0.67 15.49 2.85 97.84
8 INT4534 Regulation of PROC 38 0.33 19.81 8.99 97.08
9 INT224739 Negative_regulation of Positive_regulation of PTGER2 3 0.18 1.7 0.55 97.04
10 INT1762 Negative_regulation of PTGER2 64 0.43 28.21 11.27 97.04
11 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 96.92
12 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 96.72
13 INT148892 Binding of HPS1 13 0.37 19.21 3.35 95.16
14 INT154334 Localization of S100A12 9 0.80 9.32 2.89 92.52
15 INT343009 Negative_regulation of Protein_catabolism of SFTPA1 1 0.05 1.42 0.79 92.52
16 INT5609 Regulation of Ifx 6 0.60 5.73 3.5 92.36
17 INT263019 Gene_expression of DEFA6 4 0.25 4.14 1.17 91.72
18 INT70566 Protein_catabolism of SFTPA1 3 0.20 3.31 1.47 91.44
19 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 90.64
20 INT86071 Negative_regulation of Med15 3 0.43 1.19 3.38 90.60
21 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 90.44
22 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 89.44
23 INT20210 Localization of Ngf 69 0.79 46.22 38.57 89.40
24 INT81264 Positive_regulation of Localization of Ngf 13 0.58 9.82 9.53 89.40
25 INT222005 Regulation of HPS1 2 0.33 3.3 0.6 89.28
26 INT8835 Localization of SFTPA1 65 0.68 32.81 38.65 89.12
27 INT53240 Positive_regulation of Localization of SFTPA1 11 0.11 7.99 7.15 89.12
28 INT8836 Positive_regulation of SFTPA1 36 0.47 28.37 23.59 88.80
29 INT121818 Binding of STAT3 25 0.47 11.16 3.67 88.52
30 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 87.52
31 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18 85.68
32 INT299115 Regulation of INPP5K 6 0.39 4.11 0.59 85.44
33 INT50212 Gene_expression of Ifx 33 0.75 32.17 7.26 83.52
34 INT19392 Gene_expression of Ada 9 0.77 7.4 3.17 83.20
35 INT9220 Gene_expression of Ighg1 125 0.77 85.74 15.92 82.88
36 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 82.68
37 INT9650 Gene_expression of LPA 141 0.75 104.57 29 82.32
38 INT170606 Regulation of Gene_expression of GOPC 31 0.37 6.08 3.31 82.32
39 INT299116 Regulation of Gene_expression of INPP5K 1 0.39 1.13 0.06 82.32
40 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 81.88
41 INT204766 Gene_expression of Nod2 4 0.75 4.14 1.3 81.84
42 INT263025 Positive_regulation of Gene_expression of DEFA6 2 0.16 1 0.28 81.60
43 INT72179 Negative_regulation of Dll1 5 0.33 4.09 3.84 81.24
44 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 81.24
45 INT28894 Positive_regulation of PLK2 3 0.50 3.77 0.69 80.84
46 INT38558 Positive_regulation of DBT 9 0.31 1.59 0.86 80.44
47 INT213886 Binding of IL23R 7 0.46 16.79 6.94 80.24
48 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 79.84
49 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91 79.84
50 INT70801 Gene_expression of Hmgcr 12 0.42 3.08 4.1 79.24
51 INT15898 Positive_regulation of Prkaca 199 0.70 50.89 87.54 78.56
52 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 76.48
53 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 76.40
54 INT143846 Positive_regulation of INPP5K 5 0.40 6.4 1.17 76.24
55 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03 76.12
56 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 75.76
57 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 75.76
58 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 75.20
59 INT90909 Negative_regulation of Gene_expression of NOS1 44 0.55 23.83 12.47 75.20
60 INT2725 Positive_regulation of FCER2 23 0.69 23.08 4.7 75.00
61 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 75.00
62 INT4936 Localization of Tacr1 125 0.80 35.7 107.7 75.00
63 INT38731 Localization of Trpv1 138 0.81 52.73 90.49 75.00
64 INT74376 Gene_expression of Cnr1 173 0.78 73.43 89.7 75.00
65 INT76620 Gene_expression of Cnr2 93 0.78 34.7 50.14 75.00
66 INT96624 Positive_regulation of Positive_regulation of Trpv1 62 0.70 20.5 34.28 75.00
67 INT87976 Regulation of Gene_expression of Cnr1 9 0.58 6.87 7.51 75.00
68 INT108007 Regulation of Gene_expression of Cnr2 2 0.44 0.39 1.17 75.00
69 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 74.84
70 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72 74.84
71 INT6481 Binding of TNF 624 0.48 510.2 214.82 74.04
72 INT348186 Binding of KIF21B 1 0.31 1.35 0.64 73.72
73 INT227413 Gene_expression of DLAT 12 0.44 13.21 1.36 73.56
74 INT44015 Binding of Cd86 16 0.31 5.92 3.58 73.20
75 INT56160 Binding of Ifx 14 0.36 11.39 5.74 72.00
76 INT238637 Binding of Ada 2 0.26 1.01 0.94 71.68
77 INT28561 Regulation of Gene_expression of SOD1 9 0.61 2.83 0.71 69.40
78 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 69.12
79 INT93684 Gene_expression of STAT3 66 0.78 34.42 5.94 68.72
80 INT169015 Gene_expression of FOXP3 50 0.60 33.18 8.4 68.68
81 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 68.68
82 INT9660 Regulation of TNF 363 0.62 312.94 139.99 67.28
83 INT231573 Binding of PTPN22 5 0.44 7.94 2.33 66.80
84 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9 65.84
85 INT182667 Binding of DLAT 11 0.31 40.75 2.8 65.84
86 INT40486 Positive_regulation of Positive_regulation of ADCY1 20 0.48 4.29 11.33 65.84
87 INT346908 Negative_regulation of DEFA5 1 0.03 0.41 0.11 64.08
88 INT125006 Gene_expression of DEFA5 2 0.05 3.38 0.38 62.92
89 INT132881 Binding of INPP5K 7 0.48 4.35 0.33 62.88
90 INT238636 Regulation of Ada 2 0.15 1.12 1.06 62.44
91 INT9647 Gene_expression of PROC 163 0.65 89.76 26.75 61.72
92 INT27651 Gene_expression of S100A12 45 0.76 52.25 10.51 61.20
93 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 60.84
94 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76 60.60
95 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47 60.28
96 INT14884 Positive_regulation of Gene_expression of SFTPA1 32 0.25 20.37 26.09 60.28
97 INT9489 Gene_expression of SFTPA1 112 0.66 55.38 66.45 60.28
98 INT25989 Localization of Vip 31 0.68 10.53 10.35 58.52
99 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61 58.32
100 INT35802 Positive_regulation of Vip 16 0.40 21.5 7.95 58.32
101 INT179428 Binding of FANCE 5 0.34 3.65 2.74 57.92
102 INT92653 Gene_expression of IL12B 21 0.75 17.28 3.89 57.84
103 INT28336 Positive_regulation of Pax3 37 0.33 20.94 25.66 57.76
104 INT92447 Negative_regulation of Gene_expression of SFTPA1 6 0.35 2.81 5.43 55.56
105 INT37148 Negative_regulation of Gene_expression of CALCA 7 0.43 1.91 4.98 55.56
106 INT284669 Gene_expression of LRRK2 3 0.65 4.58 1.14 52.20
107 INT348185 Gene_expression of MUC19 1 0.62 2.71 1.14 52.00
108 INT340345 Positive_regulation of Gene_expression of S100A12 1 0.46 1.94 0.34 51.56
109 INT626 Localization of CALCA 289 0.81 125.39 221.15 51.36
110 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8 51.36
111 INT60672 Regulation of Gene_expression of CALCA 3 0.61 1.76 2.85 51.36
112 INT25356 Positive_regulation of S100A12 18 0.69 17.62 3.38 51.16
113 INT4985 Positive_regulation of Tac1 81 0.69 35.79 50.67 50.24
114 INT33474 Negative_regulation of Ltb4r 9 0.13 4.02 3.28 50.00
115 INT202035 Gene_expression of LILRB1 5 0.75 4.78 1.41 50.00
116 INT16636 Positive_regulation of Ltb4r 8 0.26 4.48 0.92 50.00
117 INT48970 Positive_regulation of LILRB1 7 0.67 11.38 0.67 50.00
118 INT346896 Binding of Nod2 1 0.21 0.72 0.26 49.92
119 INT34590 Gene_expression of ALPP 199 0.75 89.85 15.1 49.36
120 INT11823 Positive_regulation of GGT1 53 0.67 45.84 7.55 46.92
121 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 45.36
122 INT9377 Positive_regulation of Positive_regulation of TRPV1 43 0.70 15.81 24.47 43.28
123 INT94464 Negative_regulation of Hand1 44 0.41 31.5 12.39 43.16
124 INT300539 Gene_expression of Rorc 2 0.47 5.8 2 42.88
125 INT224648 Gene_expression of Il21 15 0.39 18.71 7.47 42.28
126 INT353932 Positive_regulation of Gene_expression of Il21 1 0.30 0.16 0.27 42.28
127 INT80036 Positive_regulation of FAS 42 0.67 42.22 9.4 38.04
128 INT163666 Localization of Cat 8 0.80 5.84 1.57 34.40
129 INT353935 Transcription of Rorc 1 0.48 3.54 0.93 34.40
130 INT206136 Positive_regulation of Gene_expression of STAT3 14 0.46 4.3 1.1 32.92
131 INT5160 Localization of PTAFR 61 0.80 42.6 19.16 32.00
132 INT13302 Binding of PTAFR 20 0.48 7.03 3.7 32.00
133 INT18007 Positive_regulation of C6orf25 23 0.66 14.98 1.95 30.12
134 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 29.40
135 INT227415 Regulation of DLAT 2 0.29 2.93 0.28 22.84
136 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 21.92
137 INT95481 Regulation of Gene_expression of TRPV1 48 0.62 29.3 26.28 21.92
138 INT181405 Gene_expression of Ccl20 26 0.65 23.02 9.46 21.52
139 INT13303 Positive_regulation of PTAFR 40 0.69 16.27 11.56 20.72
140 INT343012 Positive_regulation of HCL1 1 0.04 0.33 1.13 20.28
141 INT346897 Positive_regulation of Atg16l1 1 0.16 0.57 0.19 18.56
142 INT55469 Positive_regulation of Positive_regulation of PTAFR 9 0.47 3 2.17 14.52
143 INT91519 Negative_regulation of Positive_regulation of PTAFR 4 0.41 1.52 2.15 14.20
144 INT159709 Binding of ERAP1 12 0.47 3.42 2.91 13.20
145 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 12.88
146 INT25152 Gene_expression of SAA1 37 0.75 53.56 8.07 12.88
147 INT353936 Positive_regulation of Transcription of Ccr6 1 0.37 0.75 0.44 10.72
148 INT353933 Transcription of Ccr6 1 0.42 0.75 0.44 10.20
149 INT10506 Gene_expression of PTAFR 86 0.76 37.57 28.58 9.12
150 INT227401 Gene_expression of Nup210 2 0.51 1.26 0.12 7.32
151 INT300540 Positive_regulation of Gene_expression of Ccr6 2 0.55 3.75 1.53 6.92
152 INT322783 Positive_regulation of Regulation of Vip 1 0.11 3.4 0.74 6.60
153 INT181344 Gene_expression of Ccr6 28 0.61 24.34 9.78 6.52
154 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31 6.40
155 INT15147 Regulation of Vip 16 0.47 12.59 6.34 6.20
156 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
157 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
158 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
159 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
160 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
161 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
162 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 5.00
163 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61 5.00
164 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
165 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
166 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
167 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
168 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 5.00
169 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
170 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
171 INT12339 Localization of IL8 437 0.81 251.87 117.39 5.00
172 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 5.00
173 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 5.00
174 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
175 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
176 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
177 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
178 INT4742 Gene_expression of Tac1 177 0.78 69.99 102.66 5.00
179 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 5.00
180 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35 5.00
181 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46 5.00
182 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97 5.00
183 INT8534 Localization of Pax3 85 0.59 28.71 82.82 5.00
184 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59 5.00
185 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 5.00
186 INT123584 Gene_expression of Trpa1 176 0.78 83 78.65 5.00
187 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35 5.00
188 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 5.00
189 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
190 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 5.00
191 INT6849 Localization of IL1B 229 0.81 112.56 69.63 5.00
192 INT14624 Gene_expression of Pax3 100 0.38 33.22 69.47 5.00
193 INT11937 Localization of Il6 228 0.81 139.83 64.39 5.00
194 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
195 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 5.00
196 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84 5.00
197 INT3950 Gene_expression of Ptger2 293 0.77 122.28 62.42 5.00
198 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72 5.00
199 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 5.00
200 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
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