D:Immune System Diseases

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Disease Term
Synonyms Disease Immune, Disease Immune System, Disease Immunologic, Disease Immunological, Diseases Immune, Diseases Immune System, Diseases Immunologic, DISEASES IMMUNOLOGICAL, Diseases Of Immune System, Disorder Immune, Disorders Immune
Documents 311
Hot Single Events 177
Hot Interactions 17

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Immune System Diseases. They are ordered first by their relevance to Immune System Diseases and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT168416 MIR146A Regulation of Irak1 1 0.24 0.99 0.59 96.20
2 INT331627 Binding of HLA-DRB3 and Pain1 1 0.00 2.15 0.14 92.40
3 INT331628 Binding of HLA-DQA2 and Pain1 1 0.01 2.13 0.14 91.12
4 INT217023 Lpar4 Regulation of Gene_expression of Ik 1 0.00 0.27 0.33 90.40
5 INT275557 Negative_regulation of Binding of CXCL10 and Cxcr3 1 0.04 1.09 0.35 86.32
6 INT275554 Binding of CXCL10 and Cxcr3 1 0.03 2.18 0.71 85.76
7 INT81546 TNF Positive_regulation of Gene_expression of Nos2 1 0.04 0.54 0.56 84.00
8 INT273723 Binding of Icam1 and Trav6-3 1 0.05 1.97 0.19 83.96
9 INT273715 Positive_regulation of Binding of Icam1 and Trav6-3 1 0.07 1.51 0.16 83.96
10 INT317895 Fos Regulation of Transcription of Egr1 1 0.41 1.03 0.17 82.96
11 INT317897 Egr1 Regulation of Transcription of Fosb 1 0.34 1.08 0.17 82.96
12 INT317889 Fos Regulation of Transcription of Fosb 1 0.30 1.08 0.17 82.96
13 INT317892 Egr1 Regulation of Transcription of Fos 1 0.41 1.03 0.17 82.96
14 INT217025 P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33 81.48
15 INT217024 Regulation of P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33 81.48
16 INT150393 Binding of CASP1 and MEFV 2 0.16 2.48 0.45 81.24
17 INT334879 CASP1 Regulation of IL1B 1 0.03 1.63 0.31 80.04
18 INT253070 Prok2 Regulation of Gene_expression of Ik 1 0.01 0.6 0.56 79.96
19 INT196644 PTGER2 Positive_regulation of Gene_expression of NA 1 0.00 0.93 0.35 79.84
20 INT273714 Positive_regulation of Binding of Icam1 and Itgb2 1 0.17 1.46 0.15 79.56
21 INT273717 Binding of Icam1 and Itgb2 1 0.17 1.45 0.15 79.56
22 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29 78.72
23 INT186385 Binding of TNF and Tnfrsf1b 4 0.30 3.24 0.42 78.72
24 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02 75.76
25 INT253072 Pbrgcsf1 Positive_regulation of Gene_expression of Prok2 1 0.15 0.44 0.33 74.00
26 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78 68.56
27 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 68.00
28 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5 68.00
29 INT299791 Negative_regulation of Binding of CD28 and CTLA4 1 0.18 0.77 0.32 68.00
30 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 65.44
31 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 65.44
32 INT299793 Positive_regulation of Binding of CD86 and CTLA4 1 0.17 1.64 0.63 65.44
33 INT299792 Positive_regulation of Binding of CD80 and CTLA4 1 0.17 1.63 0.63 65.44
34 INT315384 Adcyap1 Negative_regulation of Positive_regulation of Casp3 1 0.02 0.53 0.2 65.28
35 INT158400 Binding of CD80 and CD86 3 0.36 0.76 0.48 63.52
36 INT315386 Adcyap1 Positive_regulation of Bad 1 0.03 0.52 0.2 62.64
37 INT204790 Binding of Lat2 and Mthfd1 1 0.05 0.85 0.16 61.28
38 INT162396 Binding of LCE3B and LCE3C 1 0.32 1.08 0.45 60.88
39 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 59.28
40 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21 59.28
41 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22 57.92
42 INT273719 Binding of Itgb2 and Trav6-3 1 0.07 0.47 0.03 52.96
43 INT327334 Il10 Negative_regulation of TNF 1 0.02 1.46 0.6 48.24
44 INT209884 Binding of IL4 and TNF 1 0.04 0.73 0.26 47.52
45 INT209879 CSF2 Positive_regulation of Gene_expression of TNFRSF11B 1 0.10 0.76 0.26 46.24
46 INT327323 Il10 Positive_regulation of Gene_expression of Ttpa 1 0.02 1.43 0.58 43.36
47 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 39.36
48 INT209880 IL4 Regulation of Gene_expression of TNFRSF11B 1 0.09 0.74 0.23 39.36
49 INT188569 Binding of CD4 and TLR4 1 0.16 0.34 0.16 39.36
50 INT275549 Il10 Positive_regulation of Localization of Hand2 1 0.01 1.3 0.46 34.16
51 INT275550 Hand1 Positive_regulation of Localization of Hand2 1 0.00 1.29 0.46 33.60
52 INT204552 Sult2a2 Regulation of Cia1 1 0.01 2.75 1.75 27.92
53 INT219152 NLRP3 Positive_regulation of Positive_regulation of CASP1 1 0.02 0.83 0.1 23.44
54 INT197051 Binding of HLA-E and ATP8A1 1 0.00 6.52 1.14 22.20
55 INT205708 Binding of Icam1 and P2rx7 1 0.08 1.03 0.09 20.32
56 INT226901 Slc11a1 Regulation of Hist1h3f 1 0.02 0.41 0.15 18.24
57 INT205713 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of IL8 1 0.03 0.77 0.33 14.96
58 INT327337 MIR29A Negative_regulation of Ttpa 1 0.04 1.14 0.28 10.56
59 INT197050 Binding of HLA-DOA and HLA-E 2 0.08 1.73 0.58 9.16
60 INT188544 ETV5 Negative_regulation of Binding of IRF6 and TLR4 1 0.00 0.59 0.38 8.32
61 INT211308 Binding of Cd4 and Cd8a 3 0.19 0.3 0.31 6.16
62 INT188560 Negative_regulation of Binding of IRF6 and TLR4 1 0.04 0.58 0.38 5.60
63 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 5.00
64 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 5.00
65 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23 5.00
66 INT182194 Binding of IL8 and CXCR2 10 0.56 7.14 4.16 5.00
67 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
68 INT208572 Binding of IL8 and CXCR1 6 0.33 5.2 3.08 5.00
69 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76 5.00
70 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08 5.00
71 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95 5.00
72 INT95405 Trib3 Positive_regulation of Phosphorylation of Ephb1 3 0.08 1.33 1.89 5.00
73 INT238005 Binding of Cxcr3 and Cxcl10 2 0.38 3.73 1.42 5.00
74 INT238009 Binding of Cxcr3 and Cxcl9 3 0.40 4.01 1.37 5.00
75 INT237999 Binding of Cxcr3 and Cxcl11 2 0.45 3.49 1.11 5.00
76 INT186125 Negative_regulation of Binding of CD2 and CD58 3 0.12 3.04 1.06 5.00
77 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03 5.00
78 INT204551 Binding of Col2a1 and Positive_regulation of Cia1 1 0.03 1.74 1.03 5.00
79 INT252602 Binding of Cxcl10 and Ppig 1 0.08 1.55 0.96 5.00
80 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93 5.00
81 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89 5.00
82 INT237083 Binding of Cxcl10 and Cxcl9 2 0.39 3.19 0.87 5.00
83 INT237084 Binding of Cxcl9 and Cxcl11 2 0.34 3.19 0.87 5.00
84 INT44442 GNRH1 Positive_regulation of Localization of PLOD1 3 0.50 0.78 0.86 5.00
85 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 5.00
86 INT97795 IRF6 Positive_regulation of Localization of TNF 3 0.09 1.57 0.86 5.00
87 INT196578 Ephb1 Positive_regulation of Phosphorylation of Mapk9 1 0.13 0.5 0.85 5.00
88 INT196576 Trib3 Positive_regulation of Phosphorylation of Mapk9 1 0.02 0.5 0.85 5.00
89 INT196638 TNF Positive_regulation of F2RL1 2 0.09 1.52 0.84 5.00
90 INT196632 IL1B Positive_regulation of F2RL1 2 0.05 1.52 0.84 5.00
91 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83 5.00
92 INT188567 IRF6 Positive_regulation of Gene_expression of CD28 1 0.05 1.28 0.82 5.00
93 INT306271 IL1A Positive_regulation of Gene_expression of IL6 1 0.30 0.85 0.8 5.00
94 INT209043 Binding of Fn1 and Slc11a1 3 0.03 1.91 0.78 5.00
95 INT306259 HDAC9 Negative_regulation of Gene_expression of TNF 1 0.21 0.89 0.78 5.00
96 INT196577 Negative_regulation of Mapk14 Negative_regulation of Il6 1 0.13 0.45 0.78 5.00
97 INT306258 HDAC4 Negative_regulation of Gene_expression of TNF 1 0.09 0.89 0.78 5.00
98 INT196574 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il6 1 0.13 0.45 0.78 5.00
99 INT184116 Il10 Positive_regulation of Stat3 2 0.18 1.15 0.77 5.00
100 INT196575 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1a 1 0.04 0.44 0.77 5.00
101 INT209883 TNF Positive_regulation of Gene_expression of TNFRSF11A 1 0.20 1.83 0.77 5.00
102 INT355704 Binding of Cia1 and Aia1 1 0.00 1.85 0.77 5.00
103 INT209882 IL4 Positive_regulation of Gene_expression of TNFRSF11A 1 0.11 1.82 0.76 5.00
104 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72 5.00
105 INT172097 Binding of HLA-E and Trav6-3 10 0.02 3.71 0.71 5.00
106 INT184125 Il12a Positive_regulation of Stat4 2 0.11 1.04 0.7 5.00
107 INT306263 Binding of NFIB and TFAM 1 0.00 1.74 0.7 5.00
108 INT314596 Isg15 Negative_regulation of Gene_expression of Samhd1 1 0.05 0.17 0.7 5.00
109 INT314593 Zbp1 Negative_regulation of Gene_expression of Isg15 1 0.28 0.17 0.7 5.00
110 INT314591 Oasl1 Negative_regulation of Gene_expression of Isg15 1 0.31 0.17 0.7 5.00
111 INT314598 Isg15 Negative_regulation of Gene_expression of Oasl1 1 0.31 0.17 0.7 5.00
112 INT205706 P2rx7 Regulation of Gene_expression of Il18 1 0.21 1.35 0.7 5.00
113 INT314597 Oasl1 Negative_regulation of Gene_expression of Samhd1 1 0.06 0.17 0.7 5.00
114 INT314589 Zbp1 Negative_regulation of Gene_expression of Oasl1 1 0.31 0.17 0.7 5.00
115 INT314595 Zbp1 Negative_regulation of Gene_expression of Samhd1 1 0.05 0.17 0.7 5.00
116 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69 5.00
117 INT252603 Ppig Positive_regulation of Gene_expression of Cx3cl1 1 0.10 1.8 0.69 5.00
118 INT165583 Binding of Bdnf and Ngf 3 0.33 0.81 0.69 5.00
119 INT252605 Ppig Positive_regulation of Gene_expression of Cx3cr1 1 0.09 1.81 0.69 5.00
120 INT205702 P2rx7 Regulation of Gene_expression of Il1 1 0.04 1.38 0.67 5.00
121 INT184120 Il4 Positive_regulation of Stat6 3 0.09 2.39 0.67 5.00
122 INT314560 RYBP Positive_regulation of Gene_expression of MYC 1 0.02 0.06 0.67 5.00
123 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65 5.00
124 INT306264 Binding of IL1A and MTX1 1 0.09 0.74 0.61 5.00
125 INT252601 Binding of Cxcl10 and Cxcl11 1 0.34 1.68 0.6 5.00
126 INT275552 Tlr4 Positive_regulation of Gene_expression of Il1 1 0.00 1.28 0.59 5.00
127 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 0.07 1.42 0.58 5.00
128 INT184100 Il6 Positive_regulation of Stat1 1 0.16 0.68 0.58 5.00
129 INT350699 Binding of Casp8 and Stat3 1 0.04 1.81 0.58 5.00
130 INT350716 Binding of CD58 and Casp8 1 0.03 1.81 0.58 5.00
131 INT327339 Gtf3a Positive_regulation of VEGFA 1 0.00 2.34 0.58 5.00
132 INT299004 Binding of Il18 and Il1 1 0.04 1.16 0.58 5.00
133 INT156668 Gh Positive_regulation of Igf1 5 0.22 2.07 0.57 5.00
134 INT196585 Mapk14 Regulation of TNF 1 0.02 0.36 0.55 5.00
135 INT209885 TNFSF11 Positive_regulation of TNFRSF11A 3 0.56 3.41 0.55 5.00
136 INT244232 Binding of Ccr5 and Ccl4 3 0.17 1.48 0.55 5.00
137 INT187101 Selp Regulation of Sele 1 0.20 1.23 0.53 5.00
138 INT184111 Epo Positive_regulation of Il7 1 0.06 0.26 0.52 5.00
139 INT184130 Epo Positive_regulation of Stat5a 1 0.31 0.26 0.52 5.00
140 INT184088 Epo Positive_regulation of Il2 1 0.07 0.26 0.52 5.00
141 INT184096 Il7 Positive_regulation of Stat5a 1 0.07 0.26 0.51 5.00
142 INT184132 Il2 Positive_regulation of Stat5a 1 0.09 0.26 0.51 5.00
143 INT308656 Pik3r1 Positive_regulation of Nos3 1 0.02 1.8 0.5 5.00
144 INT206010 Foxm1 Positive_regulation of Gene_expression of Il18 1 0.03 0.72 0.5 5.00
145 INT217037 Binding of IRF6 and Il12a 1 0.01 0.08 0.5 5.00
146 INT327332 VEGFA Positive_regulation of Gene_expression of Hgfac 1 0.00 2.02 0.49 5.00
147 INT184099 Il4 Positive_regulation of Stat4 1 0.13 0.28 0.49 5.00
148 INT184105 Il6 Positive_regulation of Socs3 2 0.42 1.34 0.48 5.00
149 INT293202 IK Regulation of Gene_expression of IL17A 1 0.00 0 0.48 5.00
150 INT184094 Gene_expression of Socs3 Negative_regulation of Positive_regulation of Il6 1 0.12 1.49 0.48 5.00
151 INT184117 Il12a Positive_regulation of Stat6 1 0.07 0.28 0.48 5.00
152 INT327333 Binding of TNF and Fxr1 1 0.06 3.74 0.48 5.00
153 INT187100 Binding of Cd4 and Cd44 1 0.02 1.09 0.47 5.00
154 INT196634 IFNG Negative_regulation of DNAH8 1 0.03 1.49 0.47 5.00
155 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46 5.00
156 INT187099 Binding of Cd4 and Itga1 1 0.00 1.09 0.46 5.00
157 INT298999 Binding of Il18bp and Il18 1 0.02 0 0.45 5.00
158 INT253075 Prok2 Negative_regulation of Gene_expression of Il10 1 0.24 0.24 0.45 5.00
159 INT188564 IRF6 Positive_regulation of Gene_expression of PRF1 1 0.01 0.44 0.44 5.00
160 INT188565 IRF6 Regulation of Gene_expression of CD28 1 0.03 0.7 0.43 5.00
161 INT184124 Socs3 Regulation of Il6 1 0.13 1.4 0.43 5.00
162 INT188562 IRF6 Regulation of Gene_expression of PRF1 1 0.01 0.7 0.43 5.00
163 INT184138 Ik Positive_regulation of Stat3 1 0.01 0.29 0.43 5.00
164 INT217034 P2RX1 Regulation of Gene_expression of Ik 1 0.00 0.34 0.42 5.00
165 INT299789 IL4 Negative_regulation of Gene_expression of RAE1 1 0.00 0.84 0.41 5.00
166 INT350693 Mir326 Positive_regulation of Regulation of thd 1 0.00 1.32 0.41 5.00
167 INT208461 Binding of CD4 and IL16 1 0.05 3.04 0.41 5.00
168 INT185381 TNF Regulation of TLR2 2 0.31 1.9 0.41 5.00
169 INT253076 Prok2 Positive_regulation of Ik 1 0.02 0.49 0.41 5.00
170 INT350698 Mir326 Regulation of Ets1 1 0.01 1.27 0.4 5.00
171 INT188572 CD14 Regulation of Gene_expression of CD28 1 0.11 0.6 0.4 5.00
172 INT184135 Il11ra1 Positive_regulation of Stat3 1 0.20 0.3 0.4 5.00
173 INT299786 IL4 Negative_regulation of Gene_expression of CD5 1 0.07 0.82 0.4 5.00
174 INT184092 Il11ra1 Positive_regulation of Jak1 1 0.17 0.3 0.39 5.00
175 INT204793 T Positive_regulation of Mthfd1 1 0.00 1.32 0.39 5.00
176 INT208571 CCL21 Positive_regulation of Gene_expression of CCL16 1 0.51 0.63 0.38 5.00
177 INT184380 Binding of Fcgrt and IgG 3 0.27 1.85 0.38 5.00
178 INT217028 Adp Negative_regulation of Il12b 1 0.00 0 0.37 5.00
179 INT299790 IL4 Negative_regulation of Gene_expression of NPEPPS 1 0.00 0.86 0.37 5.00
180 INT299788 INCENP Negative_regulation of Gene_expression of NPEPPS 1 0.00 0.86 0.37 5.00
181 INT293204 Binding of CNR2 and SLC25A37 1 0.01 0 0.36 5.00
182 INT293201 GOPC Positive_regulation of Gene_expression of IFN1@ 1 0.14 0.18 0.36 5.00
183 INT306254 Binding of TLR2 and LY96 1 0.25 1.29 0.36 5.00
184 INT188563 TLR4 Positive_regulation of Gene_expression of PRF1 1 0.03 0.78 0.36 5.00
185 INT308653 Proc Regulation of Gene_expression of Mapk8 1 0.00 1.48 0.36 5.00
186 INT184128 Socs3 Negative_regulation of Il6 1 0.12 1.14 0.36 5.00
187 INT184142 Il6 Negative_regulation of Positive_regulation of TNF 1 0.02 0.48 0.35 5.00
188 INT205704 P2rx7 Regulation of Localization of Il18 1 0.09 0.67 0.35 5.00
189 INT327308 Binding of Elavl1 and Ttpa 1 0.02 1.73 0.34 5.00
190 INT184095 Il10 Positive_regulation of Socs3 1 0.21 0.49 0.34 5.00
191 INT315400 IFNA1 Positive_regulation of Phosphorylation of Stat1 1 0.02 0.4 0.33 5.00
192 INT184082 Binding of Socs3 and Il6 1 0.11 0.49 0.33 5.00
193 INT205703 P2rx7 Regulation of Positive_regulation of Casp1 1 0.11 0.66 0.33 5.00
194 INT184084 Jak2 Positive_regulation of Stat1 1 0.33 0.3 0.33 5.00
195 INT184110 Jak1 Positive_regulation of Stat1 1 0.32 0.3 0.33 5.00
196 INT205711 P2rx7 Regulation of Localization of IL8 1 0.02 0.92 0.33 5.00
197 INT350701 Mthfd1 Regulation of Gene_expression of Cd4 1 0.03 1.46 0.33 5.00
198 INT184107 Cish Negative_regulation of Ik 1 0.01 0.1 0.32 5.00
199 INT308667 Binding of Chrm1 and Positive_regulation of Binding of App 1 0.04 1.14 0.32 5.00
200 INT315385 Adcyap1 Positive_regulation of Phosphorylation of Bad 1 0.05 0.44 0.32 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Immune System Diseases. They are ordered first by their pain relevance and then by number of times they were reported in Immune System Diseases. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT273704 Binding of Itgb2 3 0.20 2.59 0.1 100.00
2 INT158672 Positive_regulation of Calm1 10 0.44 4.79 5.86 99.90
3 INT58484 Regulation of Il4 12 0.45 8.67 6.09 99.56
4 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 99.44
5 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 99.40
6 INT19330 Binding of HLA-A 99 0.48 76.26 22.85 99.12
7 INT16976 Negative_regulation of IL36RN 6 0.49 5.08 3.31 99.08
8 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 99.04
9 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 99.04
10 INT169952 Gene_expression of E2f1 12 0.64 4.35 0.43 99.04
11 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17 98.98
12 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 98.98
13 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 98.80
14 INT168414 Binding of MIR146A 2 0.35 1.39 0.48 98.68
15 INT2065 Binding of BTG3 15 0.36 10.9 4.65 98.20
16 INT58897 Regulation of Localization of Adcyap1 4 0.45 1.82 3.48 98.20
17 INT208467 Positive_regulation of IL16 31 0.67 40.09 2.56 98.12
18 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 98.08
19 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 98.04
20 INT196920 Transcription of E2f1 4 0.68 2.65 0.21 97.92
21 INT10000 Regulation of Gene_expression of IL2 56 0.45 15.33 16.2 97.64
22 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 97.56
23 INT162397 Gene_expression of HLA-DRB6 1 0.06 2.26 0.7 97.56
24 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 97.52
25 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 97.32
26 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 97.22
27 INT160865 Negative_regulation of SLCO1A2 1 0.02 0.93 0.53 97.16
28 INT63169 Positive_regulation of Gene_expression of Selp 35 0.69 21.95 7.16 97.12
29 INT81880 Positive_regulation of Gene_expression of Sele 30 0.48 27.54 7.05 97.12
30 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 97.08
31 INT12339 Localization of IL8 437 0.81 251.87 117.39 96.92
32 INT205683 Localization of Ptafr 4 0.12 4.63 2.31 96.92
33 INT80822 Positive_regulation of MRGPRX1 30 0.67 3.66 7.73 96.88
34 INT43907 Binding of CD79A 28 0.48 28.11 3.04 96.88
35 INT98409 Binding of Rf 4 0.08 3.97 0.94 96.86
36 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42 96.84
37 INT49141 Gene_expression of Selp 157 0.78 85.22 24.78 96.72
38 INT61257 Gene_expression of Sele 79 0.77 70.97 17.78 96.72
39 INT83601 Binding of CNR2 30 0.47 7.79 12.37 96.56
40 INT81495 Positive_regulation of CNR2 28 0.67 14.62 14.27 96.56
41 INT312831 Negative_regulation of Lck 3 0.13 2.46 0.36 96.52
42 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59 96.40
43 INT168415 Regulation of MIR146A 2 0.26 2.94 1 96.20
44 INT58896 Localization of Adcyap1 35 0.81 4.57 14.77 96.04
45 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 95.76
46 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 95.60
47 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 95.60
48 INT187095 Negative_regulation of Positive_regulation of Il1 8 0.14 6.17 1.82 95.60
49 INT75137 Regulation of Akt1 74 0.48 37.89 9.7 95.52
50 INT55671 Gene_expression of Ik 151 0.27 80.1 48.49 95.40
51 INT2064 Positive_regulation of BTG3 29 0.49 25.58 15.37 95.16
52 INT10019 Binding of CD8A 57 0.36 31.49 10.08 94.72
53 INT265419 Negative_regulation of Binding of CD8A 2 0.08 0.9 0.14 94.72
54 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 94.08
55 INT94827 Gene_expression of HBS1L 24 0.67 26.11 1.61 94.08
56 INT21726 Gene_expression of Tfrc 10 0.74 7.38 2.36 94.00
57 INT21727 Positive_regulation of Gene_expression of Tfrc 3 0.19 1.68 0.82 94.00
58 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 93.72
59 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96 93.72
60 INT5057 Negative_regulation of Gene_expression of IFNG 23 0.58 8.33 12.3 93.72
61 INT10187 Gene_expression of Il2ra 91 0.78 52.67 16.66 93.68
62 INT61087 Positive_regulation of Gene_expression of Il2ra 12 0.35 9.1 3.25 93.68
63 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 93.12
64 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 93.12
65 INT276358 Gene_expression of MIR150 42 0.74 38.44 7.82 93.00
66 INT168410 Gene_expression of Cxcr3 81 0.75 84.03 37.01 92.76
67 INT92941 Binding of ASAP1 24 0.39 12.38 1.25 92.68
68 INT83119 Negative_regulation of Gene_expression of IL12A 24 0.42 17.52 5.69 92.60
69 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 92.24
70 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 92.20
71 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 92.12
72 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 92.12
73 INT64815 Binding of Jun 49 0.48 21.47 8.59 92.12
74 INT176524 Binding of Mapk14 19 0.43 12.54 5.21 92.12
75 INT36923 Binding of Mdk 7 0.35 3.81 2.58 92.12
76 INT64185 Gene_expression of TNFRSF11A 131 0.76 75.15 24.73 92.04
77 INT98996 Regulation of Itgb2 2 0.25 2.09 0.27 92.00
78 INT20371 Gene_expression of Cd8a 125 0.60 67.59 8.97 91.68
79 INT178175 Positive_regulation of Gene_expression of Cd8a 17 0.43 13.05 0.78 91.68
80 INT38674 Regulation of KRT20 32 0.44 19 2.15 91.28
81 INT161382 Localization of KRT20 25 0.61 12.97 2.13 91.28
82 INT277711 Regulation of Localization of KRT20 1 0.37 0.87 0.28 91.28
83 INT155156 Gene_expression of TCN1 13 0.58 3.25 0.99 91.16
84 INT169180 Binding of SNRNP70 204 0.47 119.1 29.3 91.00
85 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01 90.64
86 INT232308 Regulation of Calm1 2 0.39 2.49 1.54 90.56
87 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 90.36
88 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 90.36
89 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 90.36
90 INT277710 Regulation of Localization of ABCA1 1 0.04 1.73 0.56 89.84
91 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 89.44
92 INT10721 Gene_expression of BDNF-AS 119 0.76 72.8 16.29 89.40
93 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 89.36
94 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 89.04
95 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 89.04
96 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62 89.04
97 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 89.04
98 INT45275 Gene_expression of CSH1 39 0.62 9.39 5.85 88.88
99 INT182230 Binding of CCR9 3 0.36 4.32 2.19 88.72
100 INT219187 Negative_regulation of Binding of CCR9 1 0.16 1.37 0.38 88.72
101 INT87823 Positive_regulation of Cxcl2 51 0.66 35.47 14.79 88.48
102 INT305242 Binding of Obsty1 1 0.07 9.33 0.17 88.36
103 INT49985 Transcription of Il6 62 0.72 40.13 20.29 88.28
104 INT317880 Regulation of Gene_expression of Dusp1 2 0.42 2.98 1.94 88.08
105 INT56601 Positive_regulation of Ccl4 9 0.47 6.27 3.28 87.68
106 INT2848 Localization of ABCA1 23 0.70 10.64 4.73 87.56
107 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27 87.56
108 INT178400 Negative_regulation of Gene_expression of Dusp1 4 0.40 3.61 0.31 87.16
109 INT138696 Positive_regulation of Ccl2 57 0.67 59.57 19.58 86.96
110 INT50454 Regulation of Gene_expression of DNAH8 6 0.44 2.56 0.97 86.88
111 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 86.80
112 INT111100 Gene_expression of Dusp1 18 0.76 14.81 5.21 86.56
113 INT75841 Binding of Trav6-3 66 0.47 29.14 7.63 86.36
114 INT38276 Negative_regulation of CXCL10 10 0.42 9.26 3.19 86.32
115 INT226405 Negative_regulation of Cxcr3 3 0.23 2.79 0.77 86.32
116 INT275537 Negative_regulation of Binding of CXCL10 1 0.11 1.09 0.35 86.32
117 INT275519 Negative_regulation of Binding of Cxcr3 1 0.12 1.09 0.35 86.32
118 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 86.28
119 INT72677 Regulation of Gene_expression of Oprm1 45 0.62 13.95 26.75 86.28
120 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 86.24
121 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 86.24
122 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 86.24
123 INT93144 Gene_expression of CCR1 18 0.75 14.69 6.84 86.24
124 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 86.12
125 INT75540 Positive_regulation of TH1L 62 0.67 43.45 15.02 85.88
126 INT176386 Positive_regulation of Gene_expression of TH1L 14 0.32 9.17 3.4 85.88
127 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 85.84
128 INT213788 Gene_expression of Tfeb 18 0.66 7.9 2.07 85.84
129 INT148085 Binding of CXCL10 14 0.32 10.22 3.81 85.76
130 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 85.72
131 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 85.72
132 INT174422 Binding of Cxcr3 24 0.47 26.09 8.34 85.48
133 INT10918 Gene_expression of ITGB2 93 0.76 71.8 16.34 85.44
134 INT35460 Gene_expression of IL16 45 0.75 48.71 10.5 85.32
135 INT130557 Negative_regulation of Gene_expression of Selp 17 0.54 6.56 3.45 85.32
136 INT61263 Negative_regulation of Gene_expression of Sele 6 0.43 5.65 1.31 85.32
137 INT54834 Gene_expression of Col2a1 48 0.72 13.5 9.41 85.20
138 INT6623 Gene_expression of NA 231 0.78 45.78 59.36 84.96
139 INT26462 Gene_expression of DNAH8 44 0.78 19.36 7.31 84.96
140 INT120696 Gene_expression of SCNN1G 9 0.43 5.46 1.03 84.96
141 INT146829 Negative_regulation of Mefv 2 0.39 5.73 0.95 84.96
142 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41 84.88
143 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 84.84
144 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 84.72
145 INT97439 Positive_regulation of Il5 46 0.60 25.6 9.47 84.72
146 INT126984 Positive_regulation of Gene_expression of Il5 29 0.69 20.61 6.72 84.72
147 INT103782 Binding of Ppig 5 0.12 2.57 0.58 84.40
148 INT225312 Gene_expression of Alcam 11 0.50 7.91 0.15 84.40
149 INT70816 Negative_regulation of Fos 32 0.58 13 11.18 84.28
150 INT143684 Negative_regulation of Fosb 4 0.43 2.37 2.72 84.28
151 INT74262 Negative_regulation of Egr1 15 0.57 7.51 2.41 84.28
152 INT121970 Negative_regulation of Transcription of Fos 4 0.42 2.52 1.48 84.28
153 INT141342 Negative_regulation of Transcription of Egr1 4 0.43 2.39 0.45 84.28
154 INT317877 Negative_regulation of Transcription of Fosb 1 0.30 1.1 0.17 84.28
155 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 84.24
156 INT125312 Positive_regulation of COPD 134 0.59 162.55 20.27 84.00
157 INT20380 Gene_expression of Il5 172 0.78 104.75 34.78 83.52
158 INT90938 Gene_expression of Eng 48 0.72 15.76 1.24 83.52
159 INT129856 Positive_regulation of TNFRSF11A 26 0.68 16.21 4.75 83.24
160 INT193156 Gene_expression of CRAMP1L 17 0.42 10.96 0.18 83.00
161 INT19391 Gene_expression of Nt5e 44 0.72 13.99 5.14 82.96
162 INT47766 Transcription of Fos 25 0.69 8.78 4.42 82.96
163 INT141344 Transcription of Egr1 11 0.70 5.59 1.34 82.96
164 INT154398 Transcription of Fosb 4 0.58 1.16 0.21 82.96
165 INT89590 Negative_regulation of Gene_expression of Ccl5 8 0.36 3.97 4.67 82.40
166 INT89589 Negative_regulation of Ccl5 9 0.40 4.62 7.39 82.00
167 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21 81.92
168 INT215897 Gene_expression of Mcam 10 0.75 4.68 0.81 81.92
169 INT72782 Positive_regulation of HCC 41 0.40 63.74 2.46 81.76
170 INT145680 Regulation of P2rx7 22 0.61 11.92 5.42 81.48
171 INT213758 Regulation of Tfeb 3 0.23 0.97 0.28 81.28
172 INT37430 Gene_expression of Gpi1 61 0.63 54.63 13.87 81.04
173 INT14149 Binding of C6orf25 11 0.48 9.04 1.71 80.92
174 INT132161 Gene_expression of MTX1 48 0.58 26.55 32.32 80.64
175 INT725 Negative_regulation of IgG 62 0.41 37.21 8.16 80.64
176 INT3513 Negative_regulation of Igha 9 0.38 7.43 0.56 80.24
177 INT168411 Binding of Irak1 1 0.18 1.08 0.68 80.20
178 INT19492 Regulation of B2M 16 0.60 10.97 2.55 79.56
179 INT4643 Negative_regulation of GHR 10 0.45 3.01 2 79.52
180 INT174437 Localization of Cxcr3 3 0.71 2.36 0.79 79.36
181 INT120697 Negative_regulation of SCNN1G 6 0.32 3.53 0.92 79.12
182 INT223513 Positive_regulation of Imp3 1 0.03 3.52 0.21 78.88
183 INT56447 Positive_regulation of Icam1 64 0.64 64.14 16.16 78.68
184 INT19491 Gene_expression of CD19 44 0.75 28.8 3.47 78.60
185 INT45818 Gene_expression of C4A 35 0.75 26.4 3.52 78.32
186 INT151823 Binding of Tnfrsf1b 19 0.42 17.92 7.31 78.08
187 INT187836 Binding of Tnfrsf1a 19 0.46 18.08 4.33 78.08
188 INT35461 Positive_regulation of Gene_expression of IL16 22 0.67 25.57 4.24 78.08
189 INT278154 Regulation of Syk 1 0.05 0.98 0.22 78.08
190 INT278147 Localization of Syk 1 0.30 0.98 0.22 78.08
191 INT149816 Gene_expression of Prok2 21 0.78 18.99 15.68 78.00
192 INT70145 Gene_expression of Trav6-3 136 0.76 69.6 18.05 77.84
193 INT328756 Localization of TMX1 1 0.32 0.98 0.32 77.84
194 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 77.48
195 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 77.44
196 INT278159 Regulation of LCK 1 0.04 0.98 0.22 77.36
197 INT278161 Localization of LCK 1 0.27 0.98 0.22 77.36
198 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61 77.16
199 INT100384 Regulation of SNRNP70 24 0.60 11 3.56 76.96
200 INT278139 Regulation of Jak3 1 0.06 0.97 0.22 76.96
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