D:Impaired Glucose Tolerance

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Disease Term
Synonyms Glucose Intolerance, GLUCOSE INTOLERANCES, Glucose Tolerance, Intolerance Glucose, Intolerances Glucose
Documents 1103
Hot Single Events 200
Hot Interactions 104

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Impaired Glucose Tolerance. They are ordered first by their relevance to Impaired Glucose Tolerance and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT152361 Binding of Ifng and T2dm2 1 0.00 0.86 0.37 100.00
2 INT267684 Binding of INS and ARID1B 3 0.10 6.08 0.09 100.00
3 INT323484 Ghsr Positive_regulation of Localization of Ins1 1 0.27 0.87 0.43 100.00
4 INT323491 Olfr781 Positive_regulation of Localization of Ins1 1 0.01 0.87 0.4 100.00
5 INT317259 Pyy Positive_regulation of Ins1 1 0.02 0.33 0.12 100.00
6 INT94241 Binding of Cp and Slc2a2 1 0.13 0.81 0.67 100.00
7 INT94240 Binding of Cp and Ins1 1 0.02 0.7 0.58 100.00
8 INT278015 Gh Regulation of Ins1 1 0.10 1.47 0.27 100.00
9 INT178969 Slc7a2 Regulation of Ins1 1 0.01 0.56 0.05 99.44
10 INT242960 Binding of Ins1 and Ffar1 1 0.19 1.33 0.04 99.36
11 INT40728 SST Regulation of IRG1 1 0.11 0.36 0.38 99.36
12 INT278018 Gh Negative_regulation of Phosphorylation of Ins1 1 0.13 1.5 0.29 98.96
13 INT323485 Ghrl Negative_regulation of Localization of Ins1 1 0.15 1.99 0.05 98.76
14 INT354327 Gsk3b Positive_regulation of Gene_expression of Ide 1 0.17 0.33 0.13 98.72
15 INT304346 MIR133B Regulation of Gene_expression of MIR206 1 0.05 0.78 0.07 98.72
16 INT323503 STARD7 Positive_regulation of Ghrl 1 0.24 1.92 0.05 98.64
17 INT253148 Ins1 Regulation of Phosphorylation of Tbc1d4 1 0.09 0.42 0.09 98.48
18 INT355103 Binding of Ins2 and Ins1 1 0.12 2 0.21 98.40
19 INT323502 Ghrl Positive_regulation of Localization of Ins1 1 0.15 1.58 0.33 97.70
20 INT332638 Gip Regulation of Glp1r 1 0.02 0.47 0.05 97.26
21 INT328382 Positive_regulation of Ghrl Positive_regulation of Localization of INS 1 0.03 1.08 0.23 97.08
22 INT206059 IL6 Positive_regulation of INS 1 0.02 1.16 0.16 97.04
23 INT18325 Grem2 Positive_regulation of Ins1 1 0.02 0.9 0.88 96.88
24 INT131462 NGF Regulation of Localization of INS 1 0.40 0.97 1.2 96.44
25 INT131463 NTRK1 Regulation of Localization of INS 1 0.41 0.63 0.8 96.28
26 INT253135 Ins1 Regulation of Il6 1 0.13 0.42 0.09 96.28
27 INT350020 ARID1B Regulation of Positive_regulation of Tnf 1 0.04 1.78 0.16 96.24
28 INT292816 Binding of KCNJ11 and FTO 1 0.46 0.49 0.05 95.96
29 INT350013 ARID1B Regulation of Positive_regulation of NFKB1 1 0.00 1.77 0.16 95.92
30 INT267158 Binding of IRS1 and SHMT2 1 0.02 0.46 0.05 95.68
31 INT249833 Binding of CHI3L1 and GOPC 1 0.06 1.11 0.15 95.48
32 INT304349 Binding of HBN1 and MIR133B 1 0.00 0.29 0.07 94.68
33 INT292815 Binding of CDC123 and FTO 1 0.50 0.48 0.05 94.52
34 INT330855 Binding of Ins1 and Tgs1 1 0.02 0.86 0.09 94.16
35 INT240872 Ins1 Negative_regulation of Gene_expression of Ppargc1a 1 0.13 0.47 0.14 93.60
36 INT236588 Binding of Esr1 and Ins1 1 0.05 0.73 0.12 93.56
37 INT229330 Binding of Nr1h2 and Positive_regulation of Gene_expression of GCK 1 0.01 0.62 0.07 93.36
38 INT229333 Binding of Nr1h2 and Positive_regulation of Gene_expression of SLC2A4 1 0.02 0.62 0.07 93.36
39 INT228169 Gm2733 Regulation of Adipoq 1 0.00 0.51 0.05 93.28
40 INT246844 Binding of Irs1 and Myl7 1 0.05 0.43 0.11 92.72
41 INT323486 Ghrl Regulation of Localization of Ins1 1 0.21 2.07 0.07 92.36
42 INT242961 Ffar1 Regulation of Localization of Ins1 1 0.23 2.08 0.08 91.56
43 INT242959 Ffar1 Positive_regulation of Localization of Ins1 1 0.26 0.97 0 91.56
44 INT273520 NBN Positive_regulation of CDIPT 1 0.06 0.82 0.08 91.44
45 INT228174 RNU1-1 Positive_regulation of Gene_expression of Adipoq 1 0.12 0.55 0.08 91.20
46 INT187290 Binding of HEY1 and Gtf3a 1 0.00 6.18 0.83 90.32
47 INT143747 Binding of IL6 and LEP 2 0.04 4.05 0.38 90.28
48 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42 90.28
49 INT332269 Cndp2 Negative_regulation of Tenc1 1 0.41 0.8 0.05 90.04
50 INT217666 ADIPOQ Regulation of Gene_expression of INS 1 0.03 1.99 0.05 89.68
51 INT355570 MIF Positive_regulation of Gene_expression of IL8 1 0.07 1.11 0.36 89.28
52 INT240909 Hmgcr Regulation of Gene_expression of Sod1 1 0.03 0.53 0.14 89.04
53 INT58648 Binding of HSD11B1 and INS 1 0.04 1.65 0.07 88.68
54 INT58649 Binding of INS and Serpine1 1 0.01 1.64 0.07 88.68
55 INT172836 Binding of INS and T2dm2 1 0.00 1.65 0.08 88.56
56 INT240897 Akt1 Negative_regulation of Positive_regulation of Foxo1 1 0.21 0.22 0.08 88.40
57 INT54854 Sorbs1 Regulation of Ins1 1 0.34 0.23 0.9 88.32
58 INT328298 GHRH Negative_regulation of Localization of GHS 1 0.08 0.84 0 88.28
59 INT328296 GHRH Negative_regulation of Localization of GH1 1 0.03 0.84 0 88.28
60 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 88.20
61 INT172818 Binding of T2dm2 and Hypism 1 0.00 3.62 0.1 87.84
62 INT257466 Psd Negative_regulation of Gene_expression of Adipoq 1 0.22 0.66 0.08 87.64
63 INT207253 INS Negative_regulation of TXNIP 1 0.45 1.2 0.15 87.48
64 INT340296 Ea1 Regulation of Gene_expression of Sirt1 1 0.08 0.15 0.46 87.44
65 INT126922 Ins1 Positive_regulation of Localization of Slc2a4 1 0.23 0.75 0.11 87.40
66 INT253145 Il6 Positive_regulation of Prkag1 1 0.11 0.73 0.44 86.56
67 INT253131 Il6 Regulation of Phosphorylation of Akt1 1 0.14 0.25 0.09 86.56
68 INT328386 GHS Positive_regulation of Localization of Ghrl 1 0.10 0.88 0.17 86.20
69 INT249831 Binding of CHI3L1 and IL6 1 0.30 2.81 0.26 86.08
70 INT278016 Gh Positive_regulation of Localization of Ins1 1 0.16 1.22 0.26 85.52
71 INT301647 Negative_regulation of Mapk8 Positive_regulation of Irs1 1 0.08 0.83 0.04 85.52
72 INT301626 Mapk8 Positive_regulation of Irs1 1 0.09 0.83 0.04 85.52
73 INT253129 Ins1 Regulation of Phosphorylation of Akt1 3 0.11 1.66 0.17 85.44
74 INT278012 Gh Positive_regulation of Gene_expression of Ins1 1 0.11 1.24 0.26 85.36
75 INT229331 Binding of FXR1 and Nr1h2 1 0.02 0.61 0.05 85.36
76 INT355571 MIF Positive_regulation of IL8 1 0.04 1.05 0.44 85.28
77 INT355568 MIF Positive_regulation of IL6 1 0.05 1.05 0.44 85.28
78 INT132318 Ghrl Positive_regulation of Localization of GH1 5 0.32 4.49 0.84 84.64
79 INT350015 ARID1B Regulation of Localization of INS 1 0.03 2.6 0.04 84.44
80 INT328378 GH1 Regulation of Gene_expression of Ghrl 1 0.02 0.39 0.25 84.40
81 INT240899 Negative_regulation of Ros1 Positive_regulation of Phosphorylation of Foxo1 1 0.14 0.41 0.15 83.44
82 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69 83.44
83 INT253123 Il6 Positive_regulation of Phosphorylation of Tbc1d4 1 0.38 0.63 0.15 83.28
84 INT253141 Ins1 Positive_regulation of Phosphorylation of Tbc1d4 1 0.09 0.29 0.09 82.92
85 INT253150 Il6 Positive_regulation of Phosphorylation of Prkag1 1 0.08 0.34 0.07 82.84
86 INT253139 Il6 Positive_regulation of Phosphorylation of Stk11 1 0.26 0.34 0.07 82.84
87 INT342170 Insr Regulation of Localization of Cd320 1 0.08 0.92 0.04 82.72
88 INT240870 Negative_regulation of Ros1 Positive_regulation of Phosphorylation of Akt1 1 0.09 0.2 0.07 81.88
89 INT240877 Negative_regulation of Ros1 Positive_regulation of Phosphorylation of Ins1 1 0.03 0.2 0.07 81.88
90 INT310275 Negative_regulation of Binding of Adipoq and Ins1 1 0.19 1.14 0.09 81.80
91 INT310274 Binding of Adipoq and Ins1 1 0.21 1.14 0.09 81.80
92 INT54853 Negative_regulation of Adra1a Positive_regulation of Positive_regulation of Ins1 1 0.18 0.23 1 81.64
93 INT240807 Arc Regulation of Gene_expression of Lepr 1 0.05 0.72 0.28 81.60
94 INT7869 Gh Negative_regulation of IGF1 1 0.39 0.47 0.23 81.44
95 INT75355 Negative_regulation of GCG Regulation of Gh 1 0.01 1.26 0.18 81.32
96 INT75356 GCG Regulation of Gh 1 0.01 1.25 0.18 81.32
97 INT240809 Glp1r Positive_regulation of Localization of Ins1 1 0.15 0.16 0.04 80.96
98 INT18324 Sst Negative_regulation of Localization of Ins1 2 0.46 1.09 1.24 80.88
99 INT54852 Negative_regulation of Adra1a Positive_regulation of Ins1 1 0.18 0.23 0.99 80.88
100 INT354328 Gsk3b Regulation of Gs 1 0.16 0.84 0.07 80.80
101 INT354329 Gsk3b Regulation of Gene_expression of Gs 1 0.16 0.84 0.07 80.80
102 INT286070 Igf1 Regulation of Regulation of Ins1 1 0.10 1.7 0.2 80.64
103 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49 80.44
104 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83 80.44
105 INT229288 Binding of FXR1 and BAS 1 0.01 0.59 0.05 79.76
106 INT229275 Binding of FXR1 and BAS Negative_regulation of FXR1 1 0.00 0.59 0.05 79.76
107 INT207254 ZNF236 Positive_regulation of TXNIP 1 0.03 0.68 0.12 79.68
108 INT286071 Igf1 Regulation of Ins1 1 0.10 1.69 0.2 79.68
109 INT328385 Binding of GHS and Ghrl 1 0.15 1.89 0.45 79.60
110 INT267155 Binding of INS and SUGT1 1 0.02 0.81 0.04 79.60
111 INT36292 GCG Positive_regulation of MIA3 1 0.01 1.06 0.26 79.20
112 INT183784 INS Negative_regulation of Binding of TBK1 1 0.01 1.81 0.34 79.04
113 INT183783 INS Negative_regulation of TBK1 1 0.01 1.81 0.34 79.04
114 INT183793 INS Negative_regulation of Binding of Ros1 1 0.16 1.66 0.34 79.04
115 INT183785 INS Positive_regulation of Gene_expression of NFKBIB 1 0.03 1.83 0.34 79.04
116 INT183780 INS Negative_regulation of Gene_expression of CYBB 1 0.02 1.74 0.34 79.04
117 INT183782 INS Negative_regulation of Gene_expression of TBK1 1 0.01 1.81 0.34 79.04
118 INT236595 Binding of Esr1 and PELP1 1 0.27 0.17 0.04 79.04
119 INT225493 Binding of Esr1 and Pprc1 2 0.01 0.17 0.04 79.04
120 INT240808 Arc Regulation of Ins1 1 0.09 1.41 0.54 78.80
121 INT305335 Olfr927-ps1 Negative_regulation of Akr1b3 1 0.02 1.6 0.17 78.48
122 INT228168 Adipoq Positive_regulation of Prkag1 2 0.05 1.08 0.17 78.00
123 INT301659 Gene_expression of Mapk8 Positive_regulation of Positive_regulation of Srebf1 1 0.33 0.8 0.08 78.00
124 INT240618 Binding of INS and ADIPOQ 3 0.17 2.54 0.4 77.88
125 INT229286 BAS Negative_regulation of FXR1 1 0.02 0.55 0.09 77.88
126 INT229274 BAS Positive_regulation of BAS Negative_regulation of FXR1 1 0.00 0.55 0.09 77.88
127 INT115656 Glp1r Positive_regulation of Localization of Ins1 2 0.42 5.23 0.91 76.64
128 INT350019 Regulation of Binding of Tnf and ARID1B 1 0.04 1.34 0.1 76.40
129 INT146611 Ins1 Positive_regulation of Phosphorylation of Akt1 9 0.23 4.34 0.37 76.32
130 INT238825 LTF Regulation of Localization of RBP4 1 0.05 1.08 0.16 75.96
131 INT267707 Binding of Tnf and ARID1B 2 0.20 8.2 0.54 75.56
132 INT275849 PES1 Positive_regulation of Gene_expression of TNFAIP1 1 0.01 1.28 0.42 75.36
133 INT240888 Sod1 Regulation of Gene_expression of Ins1 1 0.08 0.18 0.04 75.36
134 INT165724 Bdkrb1 Positive_regulation of Adora1 1 0.24 1.65 0.43 75.00
135 INT207550 GH1 Regulation of Binding of GH1 and INS 1 0.22 0.55 0.07 75.00
136 INT207552 Binding of GH1 and INS 1 0.23 0.55 0.07 75.00
137 INT332304 Binding of Il6 and Adipoq 1 0.03 0.4 0.2 74.48
138 INT332639 Glp1r Negative_regulation of Localization of Gcg 1 0.03 0.87 0.07 74.32
139 INT332632 Gip Negative_regulation of Localization of Gcg 1 0.05 0.47 0.04 74.32
140 INT306945 NAMPT Positive_regulation of Positive_regulation of MAPK1 1 0.10 0.33 0.08 74.08
141 INT183786 IL6 Negative_regulation of INS 1 0.09 1.61 0.35 73.44
142 INT317394 Binding of Stk11 and Amp1 1 0.04 0.89 0.21 73.44
143 INT317399 Binding of Acc and Amp1 1 0.05 0.55 0.11 73.44
144 INT240941 Binding of Akt1 and Ins1 1 0.06 0.75 0.11 73.20
145 INT122575 Akt1 Positive_regulation of Phosphorylation of Nos3 4 0.37 3.89 0.29 72.96
146 INT122576 Pik3cd Positive_regulation of Phosphorylation of Nos3 1 0.28 0.45 0.21 72.96
147 INT172824 Positive_regulation of Binding of Tnfsf4 and T2dm2 1 0.00 2.97 0.12 72.24
148 INT172826 Binding of Tnfsf4 and T2dm2 1 0.00 5.97 0.22 71.76
149 INT301631 Gene_expression of Mapk8 Positive_regulation of Phosphorylation of Irs1 1 0.09 0.72 0.08 71.60
150 INT236596 Ncoa2 Positive_regulation of PELP1 1 0.36 0.17 0.04 71.12
151 INT290877 Binding of Bcl2a1c and Lepr 1 0.00 0.87 0.04 70.88
152 INT229329 NR0B2 Negative_regulation of Nr1h2 1 0.03 0.58 0.05 70.40
153 INT236597 Ncoa1 Positive_regulation of PELP1 1 0.41 0.17 0.03 70.40
154 INT150533 Positive_regulation of LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12 70.20
155 INT150532 LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12 69.80
156 INT249832 Binding of CHI3L1 and HRASLS 1 0.00 0.85 0.08 69.24
157 INT172832 Binding of ROS1 and Renbp 1 0.00 0.83 0.03 68.92
158 INT238827 RBP4 Positive_regulation of Gene_expression of INS 1 0.14 1.15 0 68.12
159 INT229293 Positive_regulation of FXR1 Positive_regulation of Gene_expression of NR0B2 1 0.02 0.59 0.04 67.60
160 INT291467 Binding of Hcrt and Hcrtr1 1 0.53 0.87 0.07 67.36
161 INT240875 Gene_expression of Sod1 Negative_regulation of Gene_expression of Pck1 1 0.33 0.27 0.03 66.88
162 INT240876 Gene_expression of Sod1 Negative_regulation of Pck1 1 0.33 0.27 0.03 66.88
163 INT240881 Gene_expression of Sod1 Positive_regulation of Phosphorylation of Foxo1 1 0.38 0.07 0.03 66.44
164 INT323494 Ghrl Regulation of Ins1 1 0.16 2.12 0.17 65.88
165 INT323490 Ghsr Regulation of Ins1 1 0.26 0.54 0.07 65.56
166 INT332305 Binding of CRP and Ccl2 1 0.15 0.86 0.06 65.52
167 INT321979 Negative_regulation of Klk1c8 Negative_regulation of Positive_regulation of Ins1 1 0.04 0.81 0.22 64.24
168 INT321980 Negative_regulation of Dpp4 Negative_regulation of Positive_regulation of Ins1 1 0.16 0.81 0.22 64.24
169 INT257467 Fat1 Regulation of Gene_expression of Adipoq 1 0.08 0.56 0.11 64.16
170 INT228175 RNU1-1 Regulation of Adipoq 1 0.11 0.78 0.12 63.84
171 INT317400 Acc Positive_regulation of Prkag1 1 0.29 0.06 0.03 63.64
172 INT317404 Acc Positive_regulation of Stk11 1 0.41 0.06 0.03 63.64
173 INT207551 IGF1 Positive_regulation of Gene_expression of GH1 2 0.22 1.18 0.11 63.60
174 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37 63.40
175 INT291040 Binding of CFH and INS 1 0.25 1.32 0.08 63.28
176 INT328299 Binding of GHRH and GHS 1 0.07 2.21 0.31 62.84
177 INT236586 Binding of Ncoa2 and Psmd4 1 0.12 0.22 0.03 62.48
178 INT253944 Positive_regulation of Prkca Positive_regulation of Gene_expression of Ins1 1 0.01 1.53 0.35 61.92
179 INT240883 Foxo1 Positive_regulation of Ppargc1a 1 0.43 0.06 0.03 61.88
180 INT228454 Ngf Positive_regulation of Phosphorylation of Trpv1 1 0.39 2.97 2.26 60.96
181 INT332970 Binding of Ppara and Tmed4 1 0.05 1.91 0.03 60.76
182 INT314771 Glp1r Positive_regulation of Gene_expression of Ins1 2 0.04 1.23 0.03 60.64
183 INT240894 Gcg Positive_regulation of Creb1 1 0.14 0.06 0.03 59.88
184 INT230853 Binding of SELE and VWF 1 0.06 1.3 0.07 59.52
185 INT350257 Slc12a6 Negative_regulation of Pnlip 1 0.03 1.53 0.03 57.96
186 INT316543 GH1 Regulation of Gene_expression of IGF1 1 0.03 1.32 0.09 57.24
187 INT69566 Positive_regulation of Ghrh Regulation of Gh 1 0.04 1.66 0.55 57.12
188 INT236590 Binding of Adipoq and Ncoa2 1 0.15 0.2 0.03 56.44
189 INT236587 Binding of Adipoq and Ncoa1 1 0.17 0.2 0.03 56.44
190 INT236592 Positive_regulation of Binding of Adipoq and Ncoa2 1 0.19 0.2 0.03 56.44
191 INT10844 Ghrh Regulation of Gh 13 0.13 4.77 4.71 56.40
192 INT246835 Iars Positive_regulation of Ins1 1 0.06 0.86 0.03 55.44
193 INT246838 Iars Positive_regulation of Phosphorylation of Ins1 1 0.05 0.86 0.03 54.80
194 INT352519 INS Positive_regulation of Localization of Slc2a4 1 0.07 0.97 0.03 54.40
195 INT178968 Slc7a2 Negative_regulation of Glb1 1 0.02 1.77 0.05 53.64
196 INT317247 Ffar1 Positive_regulation of Localization of Gpr119 1 0.10 0.12 0.06 52.80
197 INT317249 Gpr119 Positive_regulation of Localization of Ffar1 1 0.10 0.12 0.06 52.80
198 INT246834 Phosphorylation of Irs1 Negative_regulation of Ins1 1 0.14 0.44 0.03 51.76
199 INT236585 Ncoa2 Positive_regulation of Transcription of Ncoa1 1 0.27 0.23 0.03 50.96
200 INT280057 Zglp1 Positive_regulation of Transcription of INS 1 0.04 0.52 0.05 50.88

Single Events

The table below shows the top 200 pain related interactions that have been reported for Impaired Glucose Tolerance. They are ordered first by their pain relevance and then by number of times they were reported in Impaired Glucose Tolerance. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 100.00
2 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32 100.00
3 INT3214 Localization of Ins1 527 0.80 196.9 79.26 100.00
4 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 100.00
5 INT251 Regulation of INS 398 0.62 232.47 55.04 100.00
6 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 100.00
7 INT2276 Regulation of Ins1 234 0.61 103.78 54.05 100.00
8 INT72703 Gene_expression of Ide 79 0.70 45.04 4.47 100.00
9 INT14572 Binding of INS 205 0.48 175.43 13.38 100.00
10 INT3216 Positive_regulation of Localization of Ins1 170 0.69 56.78 35.63 100.00
11 INT18323 Negative_regulation of Localization of Ins1 122 0.58 45.74 23.04 100.00
12 INT2275 Negative_regulation of Localization of Ins1 183 0.59 51.02 44.94 100.00
13 INT1474 Regulation of Localization of Ins1 132 0.61 25.96 43.07 100.00
14 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79 100.00
15 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75 100.00
16 INT191974 Regulation of Ide 16 0.38 9.54 2.52 100.00
17 INT97777 Positive_regulation of CNBP 7 0.37 9.85 1.09 100.00
18 INT18400 Localization of Glp1r 97 0.80 11.96 24.32 100.00
19 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53 100.00
20 INT3215 Regulation of Gene_expression of Ins1 32 0.52 19.83 4.85 100.00
21 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 100.00
22 INT1289 Negative_regulation of Fglu 6 0.01 3.1 1.82 100.00
23 INT2774 Binding of Crp 241 0.48 195.89 44.39 100.00
24 INT246832 Positive_regulation of Irs1 16 0.69 7.33 0.55 100.00
25 INT246851 Negative_regulation of Gene_expression of H6PD 1 0.02 2.67 0.33 100.00
26 INT125136 Regulation of Adipoq 24 0.56 16.82 7.23 100.00
27 INT355101 Negative_regulation of Transcription of Hdl1 1 0.02 1.61 0.38 100.00
28 INT123466 Binding of T2dm2 21 0.37 34.87 2.91 100.00
29 INT207272 Negative_regulation of ZNF236 1 0.03 6.39 0.32 100.00
30 INT67078 Binding of Ifng 7 0.48 4.84 2.73 100.00
31 INT56493 Regulation of Localization of Ide 15 0.47 3.53 3.82 100.00
32 INT191978 Positive_regulation of Gene_expression of Ide 16 0.63 6.8 0.65 100.00
33 INT3483 Regulation of Fglu 3 0.01 0.52 1.11 100.00
34 INT151927 Regulation of Gene_expression of Adipoq 3 0.43 3.32 0.81 100.00
35 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 100.00
36 INT236143 Transcription of Hdl1 2 0.06 1.85 0.41 100.00
37 INT3484 Localization of Fglu 5 0.02 0.55 1.36 100.00
38 INT10299 Regulation of Localization of Fglu 1 0.01 0.37 1.03 100.00
39 INT230470 Regulation of Imgt1 1 0.00 0.65 0.17 100.00
40 INT302547 Negative_regulation of Gene_expression of Imgt1 1 0.03 2.92 0.16 100.00
41 INT207279 Localization of ZNF236 1 0.04 1.98 0.38 100.00
42 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59 100.00
43 INT219648 Gene_expression of Hd 16 0.27 8.78 0.68 100.00
44 INT240954 Localization of Ffar1 5 0.73 1.98 0.47 100.00
45 INT2581 Regulation of Binding of Ins1 7 0.61 2.05 2.08 100.00
46 INT246825 Regulation of Positive_regulation of Irs1 1 0.45 0.47 0.09 100.00
47 INT240850 Regulation of Irs1 2 0.47 0.64 0.09 100.00
48 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71 100.00
49 INT306957 Localization of NAMPT 1 0.70 8.78 0.35 100.00
50 INT302548 Gene_expression of Imgt1 1 0.05 1.46 0.08 100.00
51 INT1771 Positive_regulation of Ace 31 0.68 10.47 7.46 100.00
52 INT28954 Binding of GCG 7 0.36 3.14 1.68 100.00
53 INT85830 Positive_regulation of Gene_expression of CA9 4 0.41 5.47 1.02 100.00
54 INT85831 Positive_regulation of CA9 5 0.60 8.29 1.02 100.00
55 INT84979 Regulation of CHDH 22 0.38 22.34 0.78 100.00
56 INT182787 Binding of ETV3 14 0.37 25.44 0.37 100.00
57 INT136203 Binding of NAMSD 1 0.01 1.23 0.15 100.00
58 INT259032 Binding of PEX1 2 0.01 4.67 0.15 100.00
59 INT229749 Regulation of Gene_expression of CHDH 7 0.27 5.94 0.12 100.00
60 INT246854 Positive_regulation of Negative_regulation of SPAG8 1 0.49 0.86 0.05 100.00
61 INT47540 Binding of Cp 20 0.41 15.54 7.01 99.98
62 INT812 Localization of INS 1026 0.81 515.6 145.31 99.96
63 INT1114 Localization of Ins1 748 0.80 192.95 165.48 99.96
64 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 99.96
65 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36 99.96
66 INT2257 Localization of Gip 31 0.74 11.08 7.92 99.96
67 INT43085 Negative_regulation of Ide 28 0.39 19.96 3.45 99.96
68 INT64276 Regulation of GYS1 1 0.01 1.19 0.29 99.96
69 INT164010 Gene_expression of CNBP 7 0.53 9.13 1.71 99.92
70 INT158863 Negative_regulation of Ros1 84 0.35 40.3 10.14 99.92
71 INT1309 Positive_regulation of Localization of Gnrhr 152 0.69 24.25 81.56 99.92
72 INT176173 Positive_regulation of Nr1h2 19 0.52 10.95 1.88 99.92
73 INT267698 Gene_expression of ARID1B 18 0.63 20.47 0.47 99.92
74 INT100125 Negative_regulation of Accn3 11 0.59 5.85 4.32 99.92
75 INT178888 Gene_expression of CHDH 41 0.65 38.66 2.51 99.92
76 INT1988 Positive_regulation of Localization of Ins1 254 0.69 59.25 68.37 99.90
77 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 99.90
78 INT3217 Regulation of Ins1 154 0.62 87.11 27.29 99.90
79 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 99.90
80 INT56494 Localization of Ide 73 0.68 22.9 11.26 99.90
81 INT2578 Binding of Ins1 74 0.48 33.57 12.92 99.90
82 INT191970 Positive_regulation of Ide 29 0.51 12.94 1.4 99.90
83 INT246670 Positive_regulation of Localization of Zglp1 3 0.46 0.98 0.5 99.90
84 INT114059 Localization of Insr 10 0.46 3.49 1.87 99.90
85 INT210525 Transcription of Ide 3 0.40 1.93 0.21 99.90
86 INT21652 Negative_regulation of Negative_regulation of Ins1 7 0.39 4.16 1.46 99.90
87 INT8747 Positive_regulation of Ins1 221 0.69 154.28 35.15 99.88
88 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 99.88
89 INT70544 Negative_regulation of Fbrs 5 0.37 4.15 0.09 99.88
90 INT1200 Negative_regulation of Ins1 274 0.58 155.17 56.14 99.84
91 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46 99.84
92 INT16964 Binding of IFNG 27 0.48 14.31 2.45 99.84
93 INT227270 Regulation of Gene_expression of Adipoq 5 0.55 7.35 0.85 99.84
94 INT18322 Negative_regulation of Ins1 132 0.58 88.49 22.59 99.80
95 INT173208 Binding of CNBP 9 0.25 11.01 1.23 99.80
96 INT8742 Regulation of Localization of Ins1 65 0.61 14.98 16.43 99.80
97 INT167833 Positive_regulation of Ins2 4 0.50 6.52 0.82 99.80
98 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 99.80
99 INT18445 Regulation of Transcription of Insr 1 0.12 0.84 0.63 99.80
100 INT18446 Transcription of Insr 2 0.18 0.84 0.62 99.80
101 INT332827 Localization of GCSH 1 0.75 1.11 0.08 99.80
102 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04 99.78
103 INT39203 Positive_regulation of Negative_regulation of TRH 2 0.49 1.08 0.14 99.78
104 INT151032 Localization of Igf1 49 0.76 26.32 5.71 99.74
105 INT240955 Gene_expression of Ffar1 9 0.72 4.13 0.8 99.74
106 INT102231 Localization of HBM 8 0.60 6.14 0.88 99.70
107 INT47942 Positive_regulation of Glp1r 38 0.70 15.94 6.47 99.68
108 INT230478 Gene_expression of Hspa9 1 0.22 5.45 0.41 99.68
109 INT17035 Positive_regulation of TFPI 55 0.61 34.88 14.18 99.68
110 INT28703 Negative_regulation of TFPI 29 0.38 19.81 4.93 99.68
111 INT230475 Positive_regulation of Gene_expression of Hspa9 1 0.20 2.52 0.24 99.68
112 INT10266 Negative_regulation of Regulation of Ins1 9 0.43 3.68 1.28 99.68
113 INT121472 Positive_regulation of Glp1r 10 0.65 7.85 0.84 99.66
114 INT332608 Positive_regulation of Gene_expression of Glp1r 1 0.09 1.87 0.14 99.66
115 INT72110 Gene_expression of Glp1r 48 0.78 22.46 6.17 99.62
116 INT240800 Positive_regulation of Gene_expression of Glp1r 1 0.44 2.01 1.01 99.62
117 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58 99.60
118 INT67037 Gene_expression of Sod1 121 0.78 59.32 7.99 99.60
119 INT137332 Positive_regulation of Gene_expression of Sod1 41 0.70 19.8 4.69 99.60
120 INT127524 Localization of Zglp1 9 0.53 4.28 1.7 99.60
121 INT60151 Positive_regulation of Positive_regulation of HSD11B1 4 0.45 3.54 0.49 99.58
122 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 99.56
123 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 99.56
124 INT253118 Negative_regulation of Localization of Slc2a4 3 0.25 2.47 0.33 99.56
125 INT32795 Positive_regulation of Hypism 17 0.15 20.16 1.73 99.56
126 INT253941 Positive_regulation of Localization of Adipoq 5 0.24 2.59 0.21 99.56
127 INT154104 Binding of ARID1B 47 0.39 69.82 1.49 99.52
128 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5 99.52
129 INT184301 Negative_regulation of Bglap 16 0.56 11.22 1.22 99.52
130 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 99.48
131 INT151586 Positive_regulation of Prkag1 51 0.54 18.7 3.34 99.48
132 INT81399 Regulation of Vcam1 24 0.46 23.53 7.68 99.46
133 INT9210 Regulation of IL6 166 0.62 125.61 49.95 99.46
134 INT22454 Regulation of Crp 213 0.62 160.67 49.24 99.46
135 INT4036 Positive_regulation of Localization of Gip 3 0.45 1.92 0.9 99.44
136 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 99.44
137 INT246720 Gene_expression of Glp1r 9 0.63 6.53 0.96 99.44
138 INT55342 Negative_regulation of Gene_expression of Ros1 49 0.37 31.62 8.93 99.44
139 INT46470 Positive_regulation of Regulation of Ins1 8 0.46 4.51 1.01 99.42
140 INT246853 Positive_regulation of Gene_expression of SPAG8 1 0.45 2.09 0.65 99.40
141 INT12875 Regulation of Adra2a 26 0.45 7.51 17.35 99.40
142 INT246857 Positive_regulation of Transcription of SPAG8 1 0.45 0.78 0.12 99.40
143 INT252 Localization of GH1 529 0.80 227.4 122.05 99.38
144 INT40731 Negative_regulation of IRG1 1 0.16 0.34 0.5 99.38
145 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 99.36
146 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41 99.36
147 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.36
148 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33 99.36
149 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 99.36
150 INT45176 Negative_regulation of LPL 34 0.59 22.22 2.01 99.36
151 INT132972 Gene_expression of HADH 3 0.65 4.75 1.13 99.36
152 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 99.34
153 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 99.30
154 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97 99.30
155 INT9951 Gene_expression of ANGPTL5 45 0.53 37.2 6.44 99.30
156 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91 99.28
157 INT53775 Gene_expression of Hspd1 21 0.78 31.25 1.38 99.28
158 INT144097 Negative_regulation of Hypism 4 0.18 2.88 0.3 99.28
159 INT227273 Localization of Adipoq 22 0.72 18.04 1.72 99.26
160 INT2587 Regulation of Localization of Gcg 22 0.60 1.73 7.59 99.26
161 INT46471 Positive_regulation of Regulation of Gcg 1 0.39 0.27 0.09 99.26
162 INT15983 Regulation of Gcg 6 0.58 1.67 2.16 99.26
163 INT67348 Negative_regulation of Ghr 8 0.40 2.84 1.43 99.26
164 INT4494 Regulation of GCG 41 0.45 18.38 9.68 99.20
165 INT75907 Binding of LEP 53 0.46 46.65 8.44 99.20
166 INT96602 Positive_regulation of Binding of Ins1 4 0.65 1.59 0.7 99.18
167 INT949 Negative_regulation of TRH 12 0.43 3.06 3.4 99.18
168 INT14681 Negative_regulation of GCG 31 0.57 13.55 4.98 99.16
169 INT85829 Gene_expression of CA9 14 0.68 12.59 1.4 99.16
170 INT3315 Negative_regulation of Positive_regulation of INS 31 0.57 14.73 2.27 99.10
171 INT71106 Negative_regulation of Iapp 4 0.33 2.82 1.24 99.10
172 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8 99.08
173 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 99.04
174 INT3658 Regulation of Gcg 28 0.53 12.89 8.58 99.04
175 INT290265 Positive_regulation of FAT1 11 0.67 5.93 0.91 99.04
176 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 99.04
177 INT5288 Gene_expression of EDDM3B 5 0.05 3.04 1.09 99.04
178 INT237322 Gene_expression of Irs1 52 0.77 21.07 2 99.00
179 INT226106 Negative_regulation of Ghrl 12 0.40 3.98 5.39 99.00
180 INT26492 Negative_regulation of Localization of GCG 73 0.58 22.2 9.48 99.00
181 INT610 Regulation of PENK 47 0.62 14.17 31.55 99.00
182 INT323480 Negative_regulation of Ghsr 4 0.36 0.9 2.06 99.00
183 INT1473 Localization of Gcg 95 0.80 17.35 30.31 98.98
184 INT246856 Gene_expression of SPAG8 1 0.75 7.8 1.39 98.96
185 INT246855 Transcription of SPAG8 1 0.52 1.7 0.21 98.96
186 INT207285 Positive_regulation of Gene_expression of TXNIP 1 0.69 9.53 0.73 98.88
187 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 98.88
188 INT33220 Negative_regulation of ras 110 0.58 70.21 9.19 98.88
189 INT49103 Positive_regulation of Vcam1 71 0.69 59.52 19.85 98.88
190 INT55294 Gene_expression of Slc2a4 17 0.70 6.84 1.11 98.88
191 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 98.88
192 INT1631 Binding of Hdl1 42 0.36 49.22 2.92 98.88
193 INT344691 Negative_regulation of Binding of Hdl1 2 0.31 2.95 0.19 98.88
194 INT198505 Positive_regulation of Gene_expression of Ranbp2 1 0.50 0.49 0.42 98.88
195 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 98.86
196 INT155234 Gene_expression of TXNIP 48 0.77 24.4 2.05 98.84
197 INT2512 Negative_regulation of Cp 27 0.51 10.15 8.37 98.84
198 INT124355 Negative_regulation of BEST1 11 0.19 6.13 2.04 98.84
199 INT18583 Positive_regulation of Gene_expression of Ins1 67 0.50 49.72 8.26 98.82
200 INT15109 Gene_expression of H6PD 9 0.65 7.21 0.93 98.80
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