D:Impulse Control Disorders

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Disease Term
Synonyms Arson, Arsonism, Compulsive Shopping, Disorders Impulse Control, DISORDERS INTERMITTENT EXPLOSIVE, Explosive Disorder Intermittent, Fire Setting Behavior, FIRE SETTING BEHAVIOUR, FIRESETTING BEHAVIOR, Firesetting Behaviour, Impulse Control Disorder
Documents 173
Hot Single Events 33
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Impulse Control Disorders. They are ordered first by their relevance to Impulse Control Disorders and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT127887 SLC6A3 Regulation of Drd2 1 0.34 0.68 0.34 72.40
2 INT202573 Binding of DIO2 and DRD4 1 0.07 0.09 0.03 13.68
3 INT282506 ocd Positive_regulation of Gene_expression of Comt 1 0.32 1.26 0.84 5.00
4 INT184878 Binding of Lmo1 and ADHD1 2 0.04 2.33 0.53 5.00
5 INT189859 Binding of SLC6A3 and ADHD1 2 0.32 0.68 0.48 5.00
6 INT138384 Binding of Htr1b and ADHD1 2 0.07 1.46 0.42 5.00
7 INT282505 Binding of ocd and Slc1a1 1 0.39 4.22 0.4 5.00
8 INT258762 Binding of Dbh and ADHD1 1 0.08 1.61 0.34 5.00
9 INT258763 Binding of Drd5 and ADHD1 1 0.07 1.11 0.31 5.00
10 INT258764 Binding of Drd4 and ADHD1 1 0.08 1.11 0.31 5.00
11 INT258766 Binding of Csf2 and ADHD1 1 0.01 0.69 0.27 5.00
12 INT282501 Negative_regulation of Cyp19a1 Negative_regulation of Gene_expression of Aaiq4 1 0.01 0.6 0.27 5.00
13 INT258757 Binding of Drd2 and Rends1 1 0.00 1.26 0.25 5.00
14 INT302712 Binding of Hprt and Hrh1 1 0.25 1.07 0.2 5.00
15 INT302711 Binding of Hrh1 and Spnb4 1 0.18 1.07 0.2 5.00
16 INT260363 Gopc Regulation of Oprd1 1 0.16 0.41 0.15 5.00
17 INT267799 Binding of RLS and ADHD1 1 0.00 4.84 0.14 5.00
18 INT258761 Binding of Slc6a3 and ADHD1 1 0.03 0.51 0.12 5.00
19 INT258767 Binding of Drd2 and ADHD1 1 0.11 1.14 0.11 5.00
20 INT258765 Lmo1 Regulation of ADHD1 1 0.05 1.98 0.09 5.00
21 INT258758 Binding of Drd4 and Lmo1 1 0.04 0.64 0.08 5.00
22 INT258756 Binding of Drd5 and Lmo1 1 0.03 0.64 0.08 5.00
23 INT258768 Drd2 Regulation of ADHD1 1 0.14 0.79 0.07 5.00
24 INT342466 Binding of FFAR1 and MAFD1 1 0.03 0.87 0.05 5.00
25 INT290727 Binding of Prdm6 and Arsi 1 0.01 0.17 0.04 5.00
26 INT282503 Binding of ocd and Dlgap3 1 0.28 1.58 0.03 5.00
27 INT202572 NOVA2 Regulation of DDT 1 0.03 0.14 0 5.00
28 INT282504 Binding of Grik2 and Grik3 1 0.27 0.61 0 5.00
29 INT282507 Binding of Grik3 and ocd 1 0.25 0.61 0 5.00
30 INT202571 Binding of DRD2 and DRD4 1 0.41 0.76 0 5.00
31 INT282502 Negative_regulation of Binding of ocd and Slc1a1 1 0.30 0.48 0 5.00
32 INT273596 SMG1 Regulation of Negative_regulation of ADHD1 1 0.16 0.41 0 5.00
33 INT281402 Binding of AGRP and RAPGEFL1 1 0.05 0.29 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Impulse Control Disorders. They are ordered first by their pain relevance and then by number of times they were reported in Impulse Control Disorders. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT157192 Gene_expression of SLITRK1 7 0.28 5.77 0.63 100.00
2 INT180487 Binding of SLITRK1 2 0.39 3.91 0 100.00
3 INT180486 Positive_regulation of SLITRK1 1 0.21 3.73 0 100.00
4 INT180488 Regulation of SLITRK1 1 0.19 2.33 0 100.00
5 INT180484 Negative_regulation of SLITRK1 2 0.18 1.83 0.09 100.00
6 INT17324 Negative_regulation of Plg 26 0.38 13.5 4.05 100.00
7 INT180483 Regulation of Localization of SLITRK1 1 0.19 1.29 0 100.00
8 INT180485 Localization of SLITRK1 2 0.31 1.33 0 100.00
9 INT3127 Gene_expression of SRI 38 0.68 26.29 3.82 100.00
10 INT16478 Positive_regulation of Plg 29 0.45 18.07 4.07 100.00
11 INT154707 Gene_expression of Slitrk1 1 0.67 1.72 0.13 99.92
12 INT18190 Regulation of DRD2 11 0.60 9.01 7.63 99.84
13 INT7812 Negative_regulation of SRI 10 0.59 4.28 1.46 99.76
14 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 98.52
15 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 96.64
16 INT156170 Binding of NFYC 3 0.21 4.84 0.91 94.24
17 INT109272 Negative_regulation of Binding of DRD2 2 0.36 0.76 1.26 90.52
18 INT63839 Binding of CRS 31 0.41 34.05 4.7 90.12
19 INT49774 Binding of DRD2 48 0.48 17.42 20.73 90.04
20 INT88274 Positive_regulation of Drd4 7 0.69 3.48 4.1 87.56
21 INT248 Positive_regulation of Localization of GH1 137 0.69 49.25 32.92 86.84
22 INT252 Localization of GH1 529 0.80 227.4 122.05 86.24
23 INT202579 Regulation of Gene_expression of DRD2 4 0.41 1.11 0.99 86.04
24 INT63773 Gene_expression of DRD2 25 0.78 10.41 10.8 85.56
25 INT79361 Negative_regulation of Prdm6 5 0.51 3.79 1.4 84.40
26 INT1456 Regulation of Oprl1 61 0.62 19.5 52.87 83.44
27 INT105704 Positive_regulation of Regulation of Oprl1 2 0.46 1.23 1.95 83.44
28 INT5604 Positive_regulation of Drd2 47 0.67 10.75 27.41 82.44
29 INT300926 Gene_expression of OBFC1 15 0.65 6.97 1.22 82.40
30 INT162 Regulation of Prl 794 0.62 165.01 322.24 81.68
31 INT84911 Gene_expression of SUGT1 43 0.11 19.85 4.54 81.48
32 INT49748 Binding of HTR2C 10 0.47 3.03 4.76 81.00
33 INT72677 Regulation of Gene_expression of Oprm1 45 0.62 13.95 26.75 80.44
34 INT101723 Positive_regulation of NFYC 3 0.28 3.51 1.53 78.52
35 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 78.12
36 INT156436 Positive_regulation of Gene_expression of DLGAP3 1 0.50 0.62 0.1 77.76
37 INT156434 Gene_expression of DLGAP3 1 0.78 0.62 0.1 77.76
38 INT85849 Regulation of behavior 3 0.07 0.85 0.57 75.00
39 INT921 Regulation of GH1 172 0.60 52.88 51.04 75.00
40 INT155309 Negative_regulation of Oas1g 2 0.07 0.75 0.38 74.84
41 INT159564 Negative_regulation of Gene_expression of Oas1g 1 0.05 0.22 0 74.84
42 INT159563 Gene_expression of Oas1g 2 0.16 0.36 0.07 74.32
43 INT159423 Binding of ANKK1 4 0.47 0.9 1.35 73.96
44 INT7581 Binding of ADHD1 132 0.46 135.1 19.73 73.80
45 INT9815 Binding of FFAR1 6 0.29 3.54 0.29 70.96
46 INT201130 Localization of AES 31 0.63 25.45 5.12 68.48
47 INT327116 Positive_regulation of Localization of AES 4 0.22 2.69 0.55 67.60
48 INT112730 Positive_regulation of ZNRF1 3 0.06 2.97 0.24 64.40
49 INT189863 Gene_expression of DRD4 11 0.68 7.65 2.66 64.00
50 INT231011 Regulation of ADAMTS10 1 0.03 0.3 0 62.64
51 INT188844 Gene_expression of AES 44 0.58 33.94 5.85 61.68
52 INT62629 Localization of CNR1 35 0.76 11.86 16.3 61.64
53 INT15527 Gene_expression of FFAR1 19 0.61 11.15 1.08 59.60
54 INT243198 Gene_expression of ZNRF1 2 0.09 4.05 0.09 54.40
55 INT29352 Negative_regulation of Oprd1 16 0.58 6.51 14.6 53.88
56 INT6323 Positive_regulation of Gabrg1 213 0.70 45.08 124.34 52.16
57 INT63840 Positive_regulation of Positive_regulation of Gabrg1 9 0.49 0.9 4.11 52.16
58 INT156437 Binding of DLG4 2 0.35 0.29 0.07 49.36
59 INT156435 Binding of DLGAP1 1 0.11 0.23 0.07 49.36
60 INT168479 Binding of BAG3 13 0.36 10.68 4.21 33.96
61 INT2416 Negative_regulation of MAOA 92 0.59 42.24 36.5 26.52
62 INT246083 Positive_regulation of Cacna1d 1 0.02 0.89 0.22 25.76
63 INT7093 Negative_regulation of CYP2B6 146 0.58 37.3 48.39 25.00
64 INT13501 Binding of Drd2 65 0.48 23.76 35.6 25.00
65 INT39914 Negative_regulation of Cyp1a2 44 0.58 10.04 22 25.00
66 INT67855 Negative_regulation of PPIG 64 0.57 17.83 13.54 25.00
67 INT177992 Positive_regulation of SNRNP70 28 0.49 16.14 4.28 23.28
68 INT956 Negative_regulation of PRL 94 0.59 42.72 23.01 15.76
69 INT277117 Positive_regulation of POMZP3 2 0.09 0.22 0.09 8.72
70 INT258746 Binding of Rends1 1 0.01 1.57 0.68 7.68
71 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 5.00
72 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85 5.00
73 INT26472 Regulation of Oprm1 191 0.62 35.84 173.1 5.00
74 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28 5.00
75 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
76 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 5.00
77 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
78 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 5.00
79 INT1281 Negative_regulation of Maoa 203 0.59 22.47 91.66 5.00
80 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 5.00
81 INT2289 Gene_expression of PENK 203 0.78 55.62 79.49 5.00
82 INT4153 Binding of Insrr 109 0.40 17.99 72.15 5.00
83 INT14049 Positive_regulation of GRIN1 102 0.70 48.31 71.06 5.00
84 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 5.00
85 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 5.00
86 INT96533 Gene_expression of Slc1a3 72 0.78 26.85 55.31 5.00
87 INT251 Regulation of INS 398 0.62 232.47 55.04 5.00
88 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64 5.00
89 INT5704 Binding of Slc3a1 78 0.43 8.52 51.78 5.00
90 INT19488 Localization of ABAT 56 0.69 21.51 50.56 5.00
91 INT2783 Gene_expression of Slc3a1 86 0.65 8.84 45.4 5.00
92 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 5.00
93 INT122953 Gene_expression of COMT 65 0.77 25.84 40.49 5.00
94 INT4862 Localization of PENK 62 0.81 11.57 40.28 5.00
95 INT16455 Gene_expression of Drd2 116 0.78 22.71 38.47 5.00
96 INT11439 Positive_regulation of Csf2 105 0.69 62.63 37.77 5.00
97 INT34465 Regulation of Oprd1 34 0.45 7.14 34.29 5.00
98 INT7133 Negative_regulation of MME 85 0.59 29.22 33.1 5.00
99 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 5.00
100 INT6683 Gene_expression of Drd2 64 0.78 11.31 32.28 5.00
101 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 5.00
102 INT12397 Gene_expression of Oprd1 53 0.78 9.1 31.31 5.00
103 INT2650 Positive_regulation of Slc3a1 50 0.57 2.95 27.52 5.00
104 INT101120 Gene_expression of Comt 63 0.77 34.75 26.13 5.00
105 INT12392 Regulation of Slc3a1 45 0.36 7.57 25.66 5.00
106 INT4877 Gene_expression of MME 184 0.78 122.82 24.78 5.00
107 INT12484 Binding of Drd2 45 0.48 15.17 24.72 5.00
108 INT5905 Negative_regulation of ELANE 113 0.59 47.43 22.09 5.00
109 INT5916 Positive_regulation of HTR1A 51 0.67 18.27 21.38 5.00
110 INT61825 Negative_regulation of Slc6a3 47 0.59 6.52 21.27 5.00
111 INT110638 Negative_regulation of COMT 43 0.59 21.03 21.05 5.00
112 INT129987 Phosphorylation of Gria1 63 0.80 20.65 21.02 5.00
113 INT170444 Binding of Gopc 172 0.39 45.05 20.71 5.00
114 INT14436 Gene_expression of Dbh 42 0.72 9.9 19.85 5.00
115 INT135629 Binding of COMT 33 0.48 16.68 19.37 5.00
116 INT75742 Binding of RLS 86 0.42 95.27 19.04 5.00
117 INT73252 Positive_regulation of Mthfd1 124 0.59 59.48 18.35 5.00
118 INT7056 Positive_regulation of Gene_expression of PENK 35 0.70 14.31 18.21 5.00
119 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09 5.00
120 INT50403 Negative_regulation of CYP2C19 55 0.59 8.97 17.79 5.00
121 INT59365 Gene_expression of HTR1A 41 0.75 16.31 16.57 5.00
122 INT164366 Localization of NLRP1 26 0.71 5.9 16.54 5.00
123 INT7952 Localization of Slc3a1 32 0.81 1.28 15.69 5.00
124 INT54356 Regulation of Slc6a3 48 0.58 5.86 15.24 5.00
125 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 5.00
126 INT54924 Gene_expression of RLS 67 0.62 83.2 14.25 5.00
127 INT65697 Positive_regulation of GRIN3B 23 0.69 12.52 13.78 5.00
128 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 5.00
129 INT35467 Gene_expression of DIO2 37 0.65 9.56 12.61 5.00
130 INT49975 Binding of SLC6A3 34 0.47 9.86 12.41 5.00
131 INT145425 Positive_regulation of NLRP1 19 0.47 6.93 12.09 5.00
132 INT184853 Gene_expression of ADHD1 87 0.65 89.2 11.8 5.00
133 INT142735 Regulation of RLS 33 0.53 45.83 11.35 5.00
134 INT48912 Localization of NOS1 52 0.77 24.14 10.92 5.00
135 INT71633 Negative_regulation of SLC6A3 25 0.59 10.5 10.69 5.00
136 INT145875 Gene_expression of Grm2 28 0.58 6.81 10.19 5.00
137 INT21214 Negative_regulation of Gene_expression of PENK 21 0.58 9.14 9.53 5.00
138 INT13296 Transcription of Drd2 17 0.66 2.7 9.07 5.00
139 INT58841 Gene_expression of HTR2A 33 0.75 9.01 9.07 5.00
140 INT184864 Gene_expression of Lmo1 16 0.26 8.09 8.48 5.00
141 INT29121 Positive_regulation of DIO2 23 0.67 6.13 8.46 5.00
142 INT146343 Regulation of Slc6a3 17 0.60 7.33 8.27 5.00
143 INT69460 Positive_regulation of Grm2 12 0.49 6.54 8.18 5.00
144 INT112104 Binding of Grin2b 21 0.44 6.78 8.16 5.00
145 INT107129 Positive_regulation of RLS 46 0.60 40.1 8.09 5.00
146 INT28457 Positive_regulation of Slc6a3 26 0.50 3.64 7.76 5.00
147 INT101121 Regulation of Comt 19 0.53 10.66 7.22 5.00
148 INT154115 Positive_regulation of Localization of PENK 5 0.49 3.15 6.93 5.00
149 INT29794 Regulation of DIO2 13 0.44 5.02 6.84 5.00
150 INT22450 Gene_expression of GPI 31 0.58 18.77 6.71 5.00
151 INT90461 Negative_regulation of DRD2 21 0.53 8.35 6.55 5.00
152 INT79822 Gene_expression of Htr1b 10 0.65 2.92 6.27 5.00
153 INT157932 Positive_regulation of ADHD1 46 0.48 52.18 6.13 5.00
154 INT34370 Positive_regulation of Cfp 26 0.46 15.21 6.12 5.00
155 INT17641 Gene_expression of NLRP1 33 0.73 8.85 6.02 5.00
156 INT170296 Regulation of Gene_expression of Gopc 33 0.38 12.49 6 5.00
157 INT103880 Positive_regulation of DRD2 9 0.67 5.57 5.93 5.00
158 INT65150 Gene_expression of Drb1 10 0.44 12.97 5.82 5.00
159 INT148968 Gene_expression of Gpbar1 29 0.56 11.9 5.66 5.00
160 INT83734 Negative_regulation of RLS 24 0.50 35.75 5.66 5.00
161 INT95048 Negative_regulation of ADHD1 61 0.51 56.01 5.62 5.00
162 INT102836 Binding of LRP2 12 0.38 11.27 5.58 5.00
163 INT81796 Binding of AGRP 62 0.36 37.19 5.3 5.00
164 INT32432 Positive_regulation of Binding of Drd2 7 0.67 2.72 5.19 5.00
165 INT57368 Regulation of ADHD1 39 0.50 42.23 5.01 5.00
166 INT125242 Localization of RLS 15 0.64 15.87 4.99 5.00
167 INT20944 Gene_expression of Mcf2l 13 0.58 5.96 4.76 5.00
168 INT14502 Gene_expression of BCHE 40 0.67 18.52 4.6 5.00
169 INT36309 Negative_regulation of DIO2 18 0.57 6.42 4.51 5.00
170 INT71676 Transcription of DRD2 5 0.69 1.19 4.47 5.00
171 INT6021 Binding of PRL 18 0.48 12.55 4.3 5.00
172 INT141665 Gene_expression of AGRP 83 0.67 43.43 4.24 5.00
173 INT85677 Positive_regulation of Gpbar1 24 0.68 8.41 4.09 5.00
174 INT173910 Gene_expression of LRP2 24 0.75 19.99 4.09 5.00
175 INT172197 Positive_regulation of Gene_expression of Comt 12 0.69 7.61 4.06 5.00
176 INT120810 Binding of Dlg4 38 0.41 3.55 4.03 5.00
177 INT119053 Positive_regulation of SLC6A3 15 0.65 2.51 4 5.00
178 INT269961 Gene_expression of Hoxb8 3 0.69 14.28 3.91 5.00
179 INT7437 Gene_expression of CFP 21 0.65 4.93 3.89 5.00
180 INT65460 Positive_regulation of Gene_expression of Oprd1 8 0.69 1.87 3.87 5.00
181 INT68695 Gene_expression of HTT 63 0.77 44.54 3.69 5.00
182 INT125622 Regulation of NLRP1 7 0.44 1.84 3.62 5.00
183 INT172198 Protein_catabolism of Comt 7 0.88 2.78 3.6 5.00
184 INT232667 Binding of Pd 17 0.16 20.76 3.58 5.00
185 INT206598 Regulation of Gene_expression of Comt 9 0.60 6 3.56 5.00
186 INT102451 Localization of CALCRL 9 0.69 0 3.25 5.00
187 INT85260 Negative_regulation of ATF7IP 14 0.41 7.08 3.17 5.00
188 INT1577 Negative_regulation of Gene_expression of PRL 24 0.59 7.7 3.15 5.00
189 INT165811 Binding of Phc1 13 0.15 5.99 3.09 5.00
190 INT198076 Gene_expression of Slc1a1 13 0.73 2.41 3.07 5.00
191 INT58756 Binding of GPI 10 0.48 7.17 3 5.00
192 INT202577 Localization of DIO2 9 0.56 1.3 2.97 5.00
193 INT147412 Binding of DRD4 11 0.47 7.57 2.77 5.00
194 INT162957 Positive_regulation of STON1 5 0.35 4.83 2.77 5.00
195 INT63112 Binding of Hrh1 6 0.17 3.83 2.76 5.00
196 INT57957 Localization of TXNRD1 14 0.64 4.01 2.7 5.00
197 INT257950 Regulation of Localization of NLRP1 3 0.08 0.27 2.6 5.00
198 INT188756 Positive_regulation of AGRP 43 0.60 23.67 2.51 5.00
199 INT229110 Positive_regulation of Positive_regulation of DIO2 3 0.26 1.08 2.31 5.00
200 INT56658 Gene_expression of Spnb4 7 0.58 5.6 2.22 5.00
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