D:Inborn Urea Cycle Disorders

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pChart

Disease Term
Synonyms DISORDER UREA CYCLE, DISORDERS UREA CYCLE, Inborn Urea Cycle Disorder, UREA CYCLE DISORDER, Urea Cycle Disorders
Documents 9
Hot Single Events 0
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Inborn Urea Cycle Disorders. They are ordered first by their relevance to Inborn Urea Cycle Disorders and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT199863 Gopc Negative_regulation of Jun 1 0.03 1.07 0 5.00
2 INT199859 Gem Positive_regulation of Phosphorylation of Mapk8 1 0.10 0.67 0 5.00
3 INT199858 Gopc Negative_regulation of Phosphorylation of Jun 1 0.03 1.08 0 5.00
4 INT199861 Xiap Regulation of Gopc 1 0.07 0.46 0 5.00
5 INT199860 Gopc Negative_regulation of Positive_regulation of Mapk8 1 0.07 1.07 0 5.00
6 INT199862 Mapk8 Negative_regulation of Jun 1 0.05 1.06 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Inborn Urea Cycle Disorders. They are ordered first by their pain relevance and then by number of times they were reported in Inborn Urea Cycle Disorders. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT220295 Gene_expression of MARS 6 0.47 4.74 0.35 73.48
2 INT220294 Positive_regulation of Gene_expression of MARS 3 0.35 2.45 0.05 73.48
3 INT184748 Phosphorylation of Gem 2 0.32 1.75 0.2 19.68
4 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 5.00
5 INT14049 Positive_regulation of GRIN1 102 0.70 48.31 71.06 5.00
6 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32 5.00
7 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
8 INT47710 Negative_regulation of GRIN1 71 0.57 25.57 34.24 5.00
9 INT666 Gene_expression of Jun 124 0.78 54.61 33.67 5.00
10 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2 5.00
11 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08 5.00
12 INT67912 Gene_expression of GRIN1 75 0.77 28.99 29.28 5.00
13 INT61664 Regulation of GRIN1 38 0.60 16.45 25.35 5.00
14 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 5.00
15 INT109316 Negative_regulation of Mapk8 72 0.59 50.59 17.24 5.00
16 INT109315 Gene_expression of Mapk8 70 0.78 45.46 11.65 5.00
17 INT96915 Phosphorylation of Mapk8 73 0.81 40.69 11.44 5.00
18 INT145695 Regulation of Mapk8 26 0.62 14.67 9.83 5.00
19 INT96912 Positive_regulation of Phosphorylation of Mapk8 29 0.69 18.33 8.14 5.00
20 INT30443 Positive_regulation of AIS 30 0.54 22.59 7.2 5.00
21 INT147583 Gene_expression of AIS 82 0.58 48.7 7.11 5.00
22 INT135291 Positive_regulation of Positive_regulation of Mapk8 24 0.64 19.37 5.16 5.00
23 INT106524 Phosphorylation of Jun 23 0.80 15.35 4.78 5.00
24 INT137634 Localization of Aifm1 17 0.80 11.8 3.45 5.00
25 INT109411 Gene_expression of SAT1 61 0.77 67.99 3.08 5.00
26 INT116143 Positive_regulation of Casp9 32 0.67 30.34 3.04 5.00
27 INT123815 Gene_expression of Parp1 42 0.67 27.82 3.02 5.00
28 INT98554 Positive_regulation of Casp8 20 0.67 21.32 2.9 5.00
29 INT14447 Localization of F2 20 0.79 12.77 2.67 5.00
30 INT65948 Binding of DNASE1L3 8 0.31 1.38 2.21 5.00
31 INT82587 Positive_regulation of Gene_expression of GRIN1 8 0.67 3.66 2.18 5.00
32 INT191678 Gene_expression of Xiap 60 0.71 57.25 1.37 5.00
33 INT175508 Protein_catabolism of Parp1 30 0.85 30 1.09 5.00
34 INT104007 Negative_regulation of Positive_regulation of GRIN1 2 0.15 1.5 0.88 5.00
35 INT165104 Negative_regulation of Negative_regulation of Mapk8 5 0.43 4.21 0.77 5.00
36 INT170388 Gene_expression of Magt1 17 0.47 8.21 0.75 5.00
37 INT147554 Gene_expression of Birc2 11 0.75 10.93 0.6 5.00
38 INT26294 Regulation of Gem 2 0.18 1.73 0.6 5.00
39 INT255313 Positive_regulation of Positive_regulation of AIS 2 0.04 3.83 0.55 5.00
40 INT147555 Negative_regulation of Birc2 12 0.57 14.1 0.43 5.00
41 INT144534 Localization of Gem 3 0.37 1.62 0.41 5.00
42 INT144533 Gene_expression of Gem 4 0.39 5.12 0.39 5.00
43 INT63222 Negative_regulation of MGAM 8 0.43 4.33 0.37 5.00
44 INT116196 Protein_catabolism of Bid 7 0.66 6.24 0.32 5.00
45 INT152745 Positive_regulation of Bid 2 0.32 2.67 0.23 5.00
46 INT199845 Positive_regulation of Gem 2 0.25 1.14 0.2 5.00
47 INT199844 Binding of Bid 3 0.24 3.92 0.19 5.00
48 INT199843 Protein_catabolism of Casp9 6 0.26 4.5 0.18 5.00
49 INT116193 Protein_catabolism of Casp8 5 0.17 4.37 0.17 5.00
50 INT199856 Negative_regulation of Protein_catabolism of Parp1 2 0.41 1.46 0.15 5.00
51 INT199848 Binding of Casp8 3 0.15 3.29 0.09 5.00
52 INT199855 Positive_regulation of Protein_catabolism of Casp9 2 0.07 1.63 0.05 5.00
53 INT199853 Positive_regulation of Ppbp 1 0.00 0.98 0.04 5.00
54 INT199851 Positive_regulation of Protein_catabolism of Casp8 1 0.07 1.04 0.04 5.00
55 INT297383 Binding of BMP8B 1 0.08 0.34 0.03 5.00
56 INT199840 Negative_regulation of Negative_regulation of Birc2 1 0.11 1.19 0 5.00
57 INT199846 Negative_regulation of Gem 1 0.17 0.97 0 5.00
58 INT185891 Gene_expression of BMP8B 4 0.54 1.58 0 5.00
59 INT199817 Phosphorylation of Hist1h2bc 1 0.03 1.62 0 5.00
60 INT297382 Negative_regulation of BMP8B 1 0.09 0.53 0 5.00
61 INT199857 Regulation of Birc2 1 0.07 0.88 0 5.00
62 INT199841 Binding of Birc2 1 0.10 0.87 0 5.00
63 INT297381 Transcription of BMP8B 1 0.15 0.36 0 5.00
64 INT199849 Regulation of Kif2a 1 0.01 0.97 0 5.00
65 INT199852 Positive_regulation of Gene_expression of Gem 1 0.20 0.96 0 5.00
66 INT199850 Positive_regulation of Localization of Aifm1 1 0.18 1.26 0 5.00
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