D:Inflammatory Pain

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Disease Term
Synonyms None
Documents 1786
Hot Single Events 200
Hot Interactions 191

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Inflammatory Pain. They are ordered first by their relevance to Inflammatory Pain and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT276863 Gpr65 Regulation of Trpv1 1 0.25 1.78 1.75 100.00
2 INT136525 Binding of Prokr1 and Trpv1 1 0.39 2.9 3.76 100.00
3 INT136514 Binding of Grm1 and Grm5 4 0.12 1.8 3.9 100.00
4 INT168206 Binding of Pik3cd and Sh3 1 0.14 0.37 0.65 100.00
5 INT168205 Binding of Dlg4 and Pik3cd 1 0.11 0.37 0.65 100.00
6 INT136273 NGF Regulation of Gene_expression of BDNF 2 0.41 1.14 1.78 100.00
7 INT339291 Casp1 Positive_regulation of Il1 2 0.12 1.63 0.8 100.00
8 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02 100.00
9 INT291011 Pomc Regulation of Gene_expression of ENG 1 0.08 0.86 0.91 100.00
10 INT113289 TRPV1 Regulation of Phosphorylation of Prkaca 1 0.02 0.1 0.37 100.00
11 INT121812 IL6 Regulation of OPRM1 1 0.22 0.27 0.65 99.92
12 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18 99.86
13 INT136420 Binding of DeltaFosB and Rorb 1 0.03 0.66 0.97 99.84
14 INT249492 Trib3 Regulation of Phosphorylation of Grin2b 1 0.01 0.23 0.35 99.84
15 INT159569 Negative_regulation of Alox5 Negative_regulation of Gene_expression of Fos 1 0.37 0.4 0.7 99.80
16 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74 99.64
17 INT119313 Cpox Regulation of Gene_expression of Ptger2 1 0.02 0.6 0.74 99.64
18 INT119314 Ptgs1 Regulation of Gene_expression of Ptger2 1 0.01 0.6 0.73 99.64
19 INT150365 Camk2a Regulation of Gene_expression of Pomc 1 0.08 0.17 0.17 99.44
20 INT96906 Plxna3 Regulation of Regulation of Prkaca 1 0.17 0.71 1.08 99.40
21 INT96905 Plxna3 Regulation of Regulation of Prkce 1 0.18 0.71 1.07 99.08
22 INT150366 Nfkb1 Regulation of Gene_expression of Pomc 1 0.03 0.17 0.17 99.08
23 INT283049 Car2 Positive_regulation of Trpa1 1 0.20 1.33 0.67 99.04
24 INT149925 Negative_regulation of Cpox Negative_regulation of Gene_expression of Pde4d 1 0.01 0.39 0.84 99.04
25 INT252857 Binding of F2rl1 and Trpa1 1 0.22 0.84 0.63 98.92
26 INT252859 Binding of Ngf and Trpa1 1 0.19 0.84 0.62 98.92
27 INT259183 Gria1 Positive_regulation of Phosphorylation of Gria2 1 0.30 0.39 0.49 98.88
28 INT163909 CCL2 Positive_regulation of Positive_regulation of Ccr2 1 0.05 0.19 0.36 98.80
29 INT348402 LPA Positive_regulation of Gene_expression of Ptgs2 1 0.01 0.62 0.48 98.56
30 INT138332 Binding of P2rx3 and F2rl1 1 0.35 0.25 0.59 98.32
31 INT124292 Binding of Trpv1 and F2rl1 1 0.46 1.1 0.81 98.24
32 INT182565 Ptger2 Regulation of Trpv1 1 0.25 1.34 1.73 97.96
33 INT182553 Ptger2 Regulation of Localization of Prkca 1 0.08 0.69 0.53 97.96
34 INT182557 Ptger2 Regulation of Regulation of Trpv1 1 0.25 0.68 0.52 97.96
35 INT182554 Ptger2 Regulation of Ptger1 1 0.11 0.68 0.52 97.96
36 INT233508 Tlr4 Regulation of Gene_expression of Gpr18 1 0.04 0.45 0.46 97.72
37 INT185489 Atp5o Negative_regulation of P2rx7 1 0.01 0.29 0.24 97.68
38 INT212658 KCNA1 Positive_regulation of Cort 1 0.00 2.58 3.36 97.28
39 INT190772 Il4 Negative_regulation of Gene_expression of Ptger2 1 0.03 1.28 1.49 97.28
40 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36 97.24
41 INT147474 Nfe2l2 Positive_regulation of Hmox1 1 0.43 0.38 0.9 97.20
42 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79 97.16
43 INT199392 Pklr Positive_regulation of Prok2 1 0.34 1.3 0.91 96.88
44 INT199393 Prok2 Positive_regulation of Prokr1 1 0.48 1.3 0.9 96.88
45 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84 96.60
46 INT163908 CCL2 Positive_regulation of Ccr2 1 0.05 0.2 0.35 96.56
47 INT261832 Trpv1 Negative_regulation of Trpa1 1 0.10 0.58 0.64 96.52
48 INT163906 CCL2 Positive_regulation of CCR2 1 0.18 0.2 0.35 96.32
49 INT261830 Hspg2 Negative_regulation of Trpa1 1 0.01 0.58 0.63 96.24
50 INT104855 Prkaca Regulation of TRPV1 3 0.06 1.52 1.92 96.16
51 INT132863 Positive_regulation of Ngf Positive_regulation of Bdnf 1 0.23 1.11 0.43 96.16
52 INT150456 Binding of Sort1 and Nts 3 0.45 0.64 1.79 96.12
53 INT195931 Binding of OPRM1 and Trpv1 1 0.07 0.87 3.43 95.76
54 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42 95.64
55 INT259180 Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49 95.64
56 INT259181 Phosphorylation of Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49 95.64
57 INT291962 Pag1 Negative_regulation of Gene_expression of Grin2b 1 0.17 1.56 0.92 95.52
58 INT199391 Pklr Positive_regulation of Prokr1 1 0.31 1.28 0.87 95.40
59 INT291966 Pag1 Positive_regulation of Gene_expression of Grin2b 1 0.19 1.91 1.06 95.36
60 INT150455 Binding of Prss12 and Nts 3 0.24 1.42 2.66 95.24
61 INT150457 Binding of Sort1 and Prss12 3 0.21 1.36 2.64 95.24
62 INT143946 Binding of Pebp1 and Mastl 1 0.00 2.04 3.82 95.04
63 INT169603 Nppb Regulation of Npr1 1 0.26 0.95 0.69 95.00
64 INT263232 Prkcg Positive_regulation of Trpv4 1 0.12 1.1 1.02 94.80
65 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65 94.44
66 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34 94.32
67 INT121728 Ngf Positive_regulation of Phosphorylation of Pik3cb 1 0.45 0.69 1.11 94.32
68 INT276864 Positive_regulation of Gpr65 Positive_regulation of Prkaca 1 0.16 0.74 0.97 94.28
69 INT103548 Binding of TRPV1 and TRPV3 3 0.37 1.82 2.28 94.24
70 INT104858 Prkaca Negative_regulation of Negative_regulation of TRPV1 2 0.10 0.41 0.64 94.20
71 INT301138 Nsa2 Positive_regulation of Il10 1 0.03 1.22 0.39 93.96
72 INT145853 Casp1 Positive_regulation of Mapk14 1 0.02 0.68 0.93 93.88
73 INT262577 Localization of Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.05 0.92 0.75 93.84
74 INT233527 Tlr4 Positive_regulation of ADORA1 1 0.00 0.45 0.47 93.56
75 INT253072 Pbrgcsf1 Positive_regulation of Gene_expression of Prok2 1 0.15 0.44 0.33 93.56
76 INT247265 Mecp2 Regulation of Fos 1 0.25 0.38 0.52 93.44
77 INT166299 Binding of Mapk14 and Gpbar1 1 0.13 0.64 0.65 93.36
78 INT166302 Negative_regulation of Binding of Mapk14 and Gpbar1 1 0.12 0.64 0.65 93.36
79 INT166303 Adrbk1 Positive_regulation of Binding of Mapk14 and Gpbar1 1 0.22 0.65 0.65 93.36
80 INT263228 Prkcg Regulation of Trpv4 1 0.07 0.36 0.5 93.36
81 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11 93.32
82 INT296448 Ush1c Regulation of Binding of Gria2 1 0.06 0.29 0.28 93.04
83 INT145592 Vamp1 Positive_regulation of Calca 1 0.01 0.28 0.73 93.00
84 INT76396 Il10 Negative_regulation of Il1b 2 0.65 1.89 1.08 92.76
85 INT233503 Tlr4 Positive_regulation of Adora2b 1 0.06 0.45 0.47 92.76
86 INT76397 Il10 Negative_regulation of Ngf 1 0.44 0.45 0.3 92.76
87 INT76395 Il10 Negative_regulation of Gene_expression of Ngf 1 0.45 0.45 0.3 92.76
88 INT249483 Binding of Ephb1 and Efnb2 1 0.02 2.35 1.66 92.64
89 INT249481 Positive_regulation of Binding of Ephb1 and Efnb2 1 0.03 1.36 1.12 92.64
90 INT276669 Negative_regulation of Prkcg Regulation of Nav1 1 0.21 0.68 1.82 92.52
91 INT276674 Negative_regulation of Nkx1-1 Regulation of Nav1 1 0.11 0.68 1.81 92.52
92 INT190130 Binding of CPOX and MRXS5 1 0.00 1.4 1.23 92.48
93 INT335435 Ngf Positive_regulation of Ltb4r 1 0.52 1.06 1.16 92.48
94 INT113243 TNF Positive_regulation of Transcription of OPRM1 1 0.23 0.84 0.51 92.48
95 INT276679 Prkcg Positive_regulation of Positive_regulation of Nkx1-1 1 0.07 0.94 3.08 92.00
96 INT195927 Binding of Prkaca and Trpv1 1 0.07 0.28 0.92 91.92
97 INT276676 Prkcg Regulation of Nav1 1 0.30 0.82 3.29 91.88
98 INT276678 Nkx1-1 Regulation of Nav1 1 0.15 0.88 3.31 91.88
99 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45 91.76
100 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45 91.76
101 INT263235 Trpv4 Regulation of Trpv1 1 0.17 0.7 0.5 91.04
102 INT138886 Binding of F11r and Tjp1 1 0.13 0.86 0.6 90.88
103 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19 90.88
104 INT113241 TRAF3IP2 Regulation of Transcription of OPRM1 1 0.05 0.82 0.52 90.88
105 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 2 0.46 0.75 2.61 90.40
106 INT125284 FSCN1 Positive_regulation of Positive_regulation of EPHB2 1 0.04 0.4 1.14 90.20
107 INT159774 Binding of GRM5 and TRPV1 1 0.40 0.5 0.51 90.16
108 INT354224 Bdnf Positive_regulation of Transcription of Accn3 1 0.09 1.04 0.95 89.60
109 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23 89.40
110 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47 89.04
111 INT296484 Binding of Gria2 and GRIP1 1 0.04 4.52 4.59 88.84
112 INT139156 Binding of Gria1 and Gria2 1 0.23 0.64 1.72 88.84
113 INT127383 Neo1 Regulation of Localization of Mpo 1 0.14 0.7 0.79 88.68
114 INT339293 Casp1 Regulation of Localization of Il1 1 0.07 1.87 0.83 88.56
115 INT285659 Binding of Faah and Mgll 1 0.15 0.99 1.11 88.56
116 INT166300 Adrbk1 Positive_regulation of Negative_regulation of Gpbar1 1 0.39 0.63 0.58 88.48
117 INT267890 Arl10 Regulation of Insrr 1 0.00 0.43 0.54 88.40
118 INT267889 St13 Regulation of Insrr 1 0.00 0.43 0.54 88.40
119 INT143578 Olr404 Negative_regulation of Positive_regulation of Fos 1 0.01 0.39 0.93 88.32
120 INT120348 Negative_regulation of Binding of DES and MYC 1 0.06 0.18 0.58 88.16
121 INT162299 Negative_regulation of Adarb1 Negative_regulation of Gene_expression of Calca 1 0.01 0.93 1 88.08
122 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03 88.00
123 INT139357 Nr1h2 Regulation of Gene_expression of Ptges 1 0.07 0.5 0.25 87.72
124 INT322132 Binding of Mbp and Trpv4 1 0.11 0.39 0.27 87.64
125 INT322127 Binding of Mbp and Ca2 1 0.01 0.39 0.27 87.64
126 INT322128 Binding of Ca2 and Trpv4 1 0.03 1.1 0.75 87.48
127 INT190788 Adcy8 Positive_regulation of Adcy1 1 0.23 0.77 0.77 87.40
128 INT120349 Binding of BDKRB1 and DES 1 0.05 0.17 0.58 87.28
129 INT120350 Binding of DES and MYC 1 0.05 0.17 0.58 87.28
130 INT117806 Binding of TRPV1 and Syt9 1 0.11 0.37 0.7 87.24
131 INT207411 Sst Negative_regulation of Gene_expression of Tacr1 1 0.05 0.76 0.69 86.88
132 INT159657 Binding of INSRR and NGF 3 0.00 1.65 1.48 86.80
133 INT160540 Binding of NGF and PSIP1 2 0.29 1.43 1.12 86.80
134 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56 86.76
135 INT66713 Binding of BDKRB1 and KNG1 2 0.22 0.39 1.53 86.76
136 INT120347 Binding of KNG1 and MYC 1 0.21 0.17 0.58 86.76
137 INT296472 Camk2a Positive_regulation of Prkaca 1 0.09 0.32 0.57 86.72
138 INT107322 Positive_regulation of TRPV1 Positive_regulation of Localization of IL8 3 0.13 1.64 2.5 86.56
139 INT121729 Negative_regulation of Ngf Positive_regulation of Ephb1 1 0.24 0.69 1.22 86.36
140 INT121724 Ngf Positive_regulation of Ephb1 1 0.40 0.68 1.21 86.36
141 INT149628 Il1b Regulation of Gene_expression of Ptgs2 1 0.30 0.84 0.84 86.16
142 INT223753 Tlr4 Positive_regulation of Gene_expression of Il10 4 0.32 1.93 0.78 85.96
143 INT222183 Binding of HDLBP and PLA2G15 1 0.01 0.7 0.57 85.96
144 INT190652 Mdk Positive_regulation of Phosphorylation of Mapk1 2 0.50 0.85 0.33 85.96
145 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21 85.92
146 INT296463 Binding of Gria1 and Pick1 1 0.16 0.32 0.59 85.84
147 INT100559 Binding of Grin1 and LOC502940 1 0.13 0.61 0.8 85.76
148 INT140659 Phax Positive_regulation of Trpv1 3 0.49 0.68 2.18 85.44
149 INT352196 Igkv12-66 Negative_regulation of Gm10404 1 0.00 1.62 1.34 85.44
150 INT281077 Binding of Gria2 and Gria3 2 0.24 0.35 1.19 85.36
151 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83 85.36
152 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94 85.04
153 INT113452 Ngf Positive_regulation of Gene_expression of ASIC3 1 0.19 1.34 2.08 84.64
154 INT127585 Binding of CNR2 and Ctbp1 1 0.00 0.6 0.76 84.40
155 INT207410 Ptger2 Regulation of Gene_expression of Tacr1 1 0.02 0.69 0.65 84.40
156 INT121813 IL6 Positive_regulation of OPRM1 1 0.28 0.28 0.58 84.32
157 INT139225 Calca Negative_regulation of Icam1 1 0.44 1.13 1.06 84.24
158 INT131564 Binding of Npw and Npbwr1 3 0.41 0.35 1.46 84.24
159 INT296486 Binding of Pick1 and GRIP1 1 0.03 0.32 0.59 84.24
160 INT185937 NOS2 Regulation of Prkaca 1 0.03 1.08 0.82 84.12
161 INT127254 Binding of Gpr176 and Npbwr1 1 0.02 0.49 0.72 84.08
162 INT259184 Binding of Gria2 and Gria1 2 0.26 0.28 0.54 83.80
163 INT275285 Ros1 Positive_regulation of Tnfrsf1a 1 0.27 1.06 0.72 83.68
164 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12 83.52
165 INT164990 Mif Positive_regulation of Gene_expression of Grina 1 0.24 0.53 0.6 83.08
166 INT127584 Binding of CNR1 and Ctbp1 1 0.00 0.6 0.75 82.88
167 INT326663 Bdnf Regulation of Positive_regulation of Arc 1 0.16 1.46 0.88 82.88
168 INT139230 Icam1 Negative_regulation of Cmklr1 1 0.19 1.13 1.07 82.84
169 INT139227 Icam1 Negative_regulation of Timp1 1 0.37 1.13 1.06 82.84
170 INT139226 Icam1 Negative_regulation of Calca 1 0.44 1.12 1.05 82.84
171 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92 82.16
172 INT82025 Negative_regulation of Binding of Ntrk1 and Ngf 1 0.47 0.64 1.37 82.16
173 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12 81.88
174 INT139957 Binding of Man1b-rs and Gprasp1 1 0.00 0.08 0.85 81.60
175 INT82024 Binding of Ngfr and Ngf 2 0.33 1.48 1.05 81.52
176 INT82021 Negative_regulation of Binding of Ngfr and Ngf 1 0.29 0.32 0.69 81.52
177 INT164286 Alox5ap Positive_regulation of Cysltr2 1 0.19 1.11 0.61 81.48
178 INT164284 Ltb4r Positive_regulation of Alox5ap 1 0.34 1.1 0.6 81.48
179 INT164285 Ltc4s Positive_regulation of Cysltr2 1 0.20 1.11 0.61 81.24
180 INT164283 Ltb4r Positive_regulation of Ltc4s 1 0.37 1.1 0.6 81.24
181 INT139229 Calca Negative_regulation of Cmklr1 1 0.19 1.12 1.06 81.16
182 INT139231 Calca Negative_regulation of Timp1 1 0.36 1.11 1.05 81.16
183 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38 81.04
184 INT149390 Foxm1 Positive_regulation of Trpa1 1 0.28 0.31 0.94 81.00
185 INT164287 Ltb4r Positive_regulation of Cysltr2 2 0.41 1.88 1.02 80.96
186 INT164281 Ltb4r Positive_regulation of Cysltr1 2 0.32 1.87 1.02 80.96
187 INT190128 Positive_regulation of PTGER1 Negative_regulation of Gene_expression of CPOX 1 0.04 1.21 1.38 80.72
188 INT296456 Gria1 Negative_regulation of Rbm39 1 0.00 0.45 0.57 80.72
189 INT149389 Olfr1241 Positive_regulation of Trpa1 1 0.02 0.31 0.94 80.68
190 INT164282 Cysltr1 Positive_regulation of Cysltr2 1 0.17 1.1 0.6 80.56
191 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25 80.28
192 INT82022 Binding of Trib3 and Ngf 1 0.08 0.31 0.68 79.92
193 INT82020 Negative_regulation of Binding of Trib3 and Ngf 1 0.07 0.31 0.68 79.92
194 INT253585 Binding of IFN1@ and Csnk2a2 1 0.24 1.35 0.64 79.60
195 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96 79.28
196 INT264947 Binding of POMC and TLR2 1 0.03 0.89 1.95 79.28
197 INT324927 Syt17 Positive_regulation of Bdkrb1 1 0.04 4.29 2.96 78.56
198 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23 78.48
199 INT270217 Binding of C2 and Ca2 1 0.03 1.63 0.81 78.40
200 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2 78.08

Single Events

The table below shows the top 200 pain related interactions that have been reported for Inflammatory Pain. They are ordered first by their pain relevance and then by number of times they were reported in Inflammatory Pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 100.00
2 INT48404 Regulation of Gene_expression of Icam1 21 0.62 15.1 7.81 100.00
3 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
4 INT24569 Negative_regulation of Pain1 26 0.41 21.82 21.08 100.00
5 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23 100.00
6 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 100.00
7 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37 100.00
8 INT9382 Regulation of TRPV1 149 0.62 53.99 77.46 100.00
9 INT178828 Regulation of Pain1 12 0.14 16.1 15.64 100.00
10 INT101501 Phosphorylation of TRPV1 31 0.82 9.26 17.27 100.00
11 INT66383 Phosphorylation of Prkaca 143 0.80 30.85 43.38 100.00
12 INT77855 Gene_expression of Pain1 55 0.75 67.42 54.1 100.00
13 INT130597 Regulation of Gene_expression of Slco1c1 1 0.07 0.76 1.37 100.00
14 INT145880 Regulation of Regulation of Pgp 1 0.37 1.26 1.45 100.00
15 INT259185 Regulation of CFM2 1 0.04 1.11 1.03 100.00
16 INT118906 Regulation of Mapk14 21 0.44 17.95 11.63 100.00
17 INT125384 Positive_regulation of Pain1 23 0.49 17.1 14.83 100.00
18 INT168681 Gene_expression of BMS1 5 0.37 2.7 1.62 100.00
19 INT118207 Binding of Ghrl 11 0.47 7.39 3.52 100.00
20 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 100.00
21 INT129973 Negative_regulation of Positive_regulation of Cnr2 2 0.30 0.72 2.51 100.00
22 INT109378 Regulation of Phosphorylation of Fos 3 0.26 1.61 2.45 100.00
23 INT145183 Negative_regulation of Gene_expression of Efnb2 2 0.17 1.51 1.31 100.00
24 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55 99.98
25 INT116996 Regulation of Pgp 9 0.51 7.51 8.01 99.98
26 INT48407 Positive_regulation of Gene_expression of Icam1 61 0.70 57.91 21.54 99.98
27 INT70996 Positive_regulation of Positive_regulation of Icam1 8 0.60 6.02 3.74 99.98
28 INT51602 Gene_expression of Grm5 59 0.75 17.29 26.99 99.98
29 INT115909 Positive_regulation of Gene_expression of Nav1 25 0.70 16.58 27.63 99.98
30 INT117676 Positive_regulation of Transcription of Nav1 8 0.53 4.37 7.75 99.98
31 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 99.96
32 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03 99.96
33 INT130424 Negative_regulation of Adcy1 19 0.58 16.31 13.6 99.96
34 INT11185 Regulation of Slco1c1 15 0.44 6.88 4.52 99.96
35 INT7134 Localization of KNG1 127 0.79 65.73 67.97 99.96
36 INT89056 Phosphorylation of Trpv1 46 0.82 13.52 22.16 99.96
37 INT75918 Negative_regulation of Negative_regulation of Cpox 19 0.23 10.05 14.4 99.96
38 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17 99.96
39 INT87611 Gene_expression of Mrgprc 6 0.64 1.92 4.84 99.96
40 INT1898 Regulation of Crh 220 0.62 61.33 102.64 99.96
41 INT264974 Positive_regulation of Negative_regulation of FPR1 1 0.27 0.1 1.02 99.96
42 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 99.92
43 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 99.92
44 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 99.92
45 INT94450 Gene_expression of Nav1 359 0.78 131.85 275.46 99.92
46 INT95646 Negative_regulation of Faah 63 0.59 25.61 36.78 99.92
47 INT112999 Gene_expression of Nosip 1 0.78 3.17 2.28 99.92
48 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 99.92
49 INT134596 Regulation of Trpa1 32 0.62 18.78 17.02 99.92
50 INT31394 Negative_regulation of Localization of Oprd1 3 0.39 2.38 7.89 99.92
51 INT83602 Positive_regulation of Gene_expression of TRPV1 114 0.70 51.19 56.35 99.92
52 INT134597 Binding of Trpa1 21 0.48 9.41 9.74 99.92
53 INT111052 Positive_regulation of Gene_expression of Nav1 44 0.70 18.98 35.28 99.92
54 INT113039 Binding of Bdkrb1 9 0.48 5.71 4.51 99.92
55 INT14126 Gene_expression of Grina 13 0.67 4.63 4.57 99.92
56 INT236487 Positive_regulation of Gene_expression of Grina 2 0.08 1.77 1.45 99.92
57 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 99.90
58 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61 99.90
59 INT89084 Gene_expression of Slco1c1 15 0.51 4.92 6.02 99.90
60 INT69764 Positive_regulation of Cnr1 126 0.70 67.8 91.49 99.90
61 INT76621 Positive_regulation of Cnr2 32 0.69 17.77 26.57 99.90
62 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.88
63 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 99.86
64 INT54284 Negative_regulation of Gene_expression of Oprd1 16 0.42 4.56 14.34 99.86
65 INT108352 Regulation of Phosphorylation of Prkaca 8 0.59 0.68 1.53 99.86
66 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 99.84
67 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 99.84
68 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 99.84
69 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05 99.84
70 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48 99.84
71 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46 99.84
72 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01 99.84
73 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 99.84
74 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 99.84
75 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08 99.84
76 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6 99.84
77 INT1163 Negative_regulation of Rbm39 64 0.29 16.8 34.74 99.84
78 INT95930 Negative_regulation of Gria2 63 0.56 18.37 17.04 99.84
79 INT8528 Negative_regulation of Gene_expression of Fos 100 0.59 41.15 55.6 99.84
80 INT6277 Positive_regulation of Gene_expression of Pomc 76 0.70 21.45 31.09 99.84
81 INT120966 Positive_regulation of Pik3cb 34 0.68 15.15 16.59 99.84
82 INT342814 Regulation of Gene_expression of PARPBP 1 0.19 1.51 3.48 99.84
83 INT346829 Negative_regulation of Efnb2 1 0.42 5.08 2.94 99.84
84 INT67620 Negative_regulation of Gene_expression of Bdnf 53 0.59 22.45 28.5 99.84
85 INT276837 Positive_regulation of Transcription of Gpr65 1 0.61 1.76 1.62 99.84
86 INT276848 Transcription of Gpr65 1 0.63 1.75 1.61 99.84
87 INT127067 Binding of FosB 2 0.37 0.66 1.06 99.84
88 INT35835 Positive_regulation of Htr2a 17 0.67 10.68 9.81 99.84
89 INT99592 Regulation of Adrbk1 3 0.61 1.46 2.84 99.84
90 INT72073 Positive_regulation of Gene_expression of NPFF 2 0.60 1.25 1.77 99.84
91 INT121723 Regulation of Positive_regulation of Pik3cb 1 0.44 0.61 1.29 99.84
92 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 99.82
93 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 99.82
94 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15 99.82
95 INT91916 Gene_expression of P2rx3 51 0.78 21.2 19.05 99.82
96 INT48956 Negative_regulation of Positive_regulation of Nos2 34 0.46 13.15 11.15 99.82
97 INT64076 Positive_regulation of Kcnma1 47 0.40 11.52 24.19 99.82
98 INT1562 Localization of Crh 499 0.81 126.74 236.68 99.80
99 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 99.80
100 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 99.80
101 INT48924 Positive_regulation of Mapk3 107 0.67 50.53 34.05 99.80
102 INT107522 Regulation of Grm5 9 0.44 6.42 11.46 99.80
103 INT158855 Binding of Mrgprx1 1 0.27 0.9 1.28 99.80
104 INT29967 Positive_regulation of Positive_regulation of Car2 40 0.40 8.03 10.13 99.80
105 INT72372 Positive_regulation of Phosphorylation of Mapk3 30 0.67 13.6 7.69 99.80
106 INT72074 Regulation of NPFF 6 0.39 3.07 5.48 99.80
107 INT97367 Gene_expression of Nav1 243 0.78 132.97 286.66 99.78
108 INT117675 Transcription of Nav1 46 0.72 30.23 44.01 99.78
109 INT81664 Positive_regulation of Gene_expression of Pnoc 12 0.68 2.51 9.75 99.78
110 INT156302 Positive_regulation of Phosphorylation of Trpv4 2 0.46 0.92 0.68 99.78
111 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 99.76
112 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 99.76
113 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66 99.76
114 INT73338 Gene_expression of Faah 21 0.77 6.72 10.73 99.76
115 INT97773 Gene_expression of Gpr18 1 0.29 0.25 0.32 99.76
116 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85 99.74
117 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49 99.74
118 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91 99.72
119 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89 99.72
120 INT104569 Gene_expression of Aqp2 23 0.60 16.56 12.23 99.72
121 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7 99.72
122 INT112207 Binding of Nav1 27 0.47 7.1 15.43 99.72
123 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75 99.72
124 INT327801 Positive_regulation of Gene_expression of Aqp2 6 0.44 7.67 7.24 99.72
125 INT166240 Regulation of Gene_expression of Cav1 3 0.51 1.03 0.43 99.72
126 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94 99.70
127 INT156134 Regulation of Gene_expression of Aqp1 5 0.59 7.2 5.3 99.70
128 INT95788 Positive_regulation of Positive_regulation of Mapk1 83 0.69 24.75 25.84 99.70
129 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92 99.68
130 INT70437 Negative_regulation of Mdk 115 0.57 41.03 35.72 99.68
131 INT35801 Regulation of Alms1 34 0.38 20.88 12.38 99.68
132 INT4892 Positive_regulation of Gene_expression of Tacr1 56 0.69 25.64 34.69 99.68
133 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 99.68
134 INT8881 Regulation of Gene_expression of Tacr1 38 0.61 17.49 27.19 99.68
135 INT3969 Positive_regulation of Sds 27 0.69 7.52 12.31 99.68
136 INT3926 Regulation of Bdkrb1 22 0.61 16.72 16.1 99.68
137 INT276825 Positive_regulation of Gene_expression of Gpr68 1 0.29 1.1 0.62 99.68
138 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 99.66
139 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82 99.66
140 INT4936 Localization of Tacr1 125 0.80 35.7 107.7 99.64
141 INT57878 Positive_regulation of Gene_expression of Egr1 36 0.70 20.42 14.45 99.64
142 INT70504 Regulation of Gene_expression of NOS1 30 0.51 21.72 21.72 99.64
143 INT3950 Gene_expression of Ptger2 293 0.77 122.28 62.42 99.64
144 INT23435 Positive_regulation of NGF 54 0.70 32.41 30.11 99.64
145 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19 99.64
146 INT130472 Negative_regulation of Phosphorylation of Grin2b 4 0.40 4.4 5.78 99.64
147 INT1004 Regulation of Sst 140 0.62 18.52 94.84 99.64
148 INT82305 Regulation of Localization of Bdnf 10 0.40 3 3.62 99.64
149 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75 99.60
150 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 99.60
151 INT145879 Positive_regulation of Gene_expression of Pgp 2 0.30 1.23 1.63 99.60
152 INT135258 Gene_expression of Pgp 4 0.47 1.28 1.96 99.60
153 INT5324 Binding of Htr2a 23 0.47 7.14 14.66 99.60
154 INT19949 Regulation of Positive_regulation of Fos 36 0.60 6.11 22.05 99.60
155 INT63854 Regulation of Gene_expression of Prkcg 27 0.56 9.41 14.15 99.60
156 INT12569 Localization of Oprd1 94 0.81 23.81 104.56 99.58
157 INT72375 Phosphorylation of Mapk3 87 0.80 43.66 30.27 99.58
158 INT32935 Binding of Pgrmc1 4 0.21 1.14 2.84 99.58
159 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76 99.56
160 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71 99.56
161 INT64111 Negative_regulation of Gene_expression of Nos1 22 0.57 8.96 6.02 99.56
162 INT5922 Gene_expression of Rtn4 27 0.48 12.7 17.86 99.56
163 INT75546 Transcription of Rtn4 1 0.06 2.87 5.03 99.56
164 INT12463 Binding of FPR1 21 0.48 3.16 7.98 99.56
165 INT12707 Negative_regulation of Binding of FPR1 9 0.59 1.45 3.72 99.56
166 INT1456 Regulation of Oprl1 61 0.62 19.5 52.87 99.54
167 INT46460 Gene_expression of NAV1 288 0.78 135.51 305.75 99.52
168 INT61873 Gene_expression of Arc 128 0.78 128.25 52.24 99.52
169 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 99.52
170 INT105287 Positive_regulation of Slco1c1 24 0.34 15.41 6.81 99.52
171 INT119470 Regulation of Ptger4 6 0.43 3.94 3.24 99.52
172 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 99.52
173 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 99.52
174 INT85328 Negative_regulation of Aqp1 5 0.54 6.02 4.94 99.52
175 INT156299 Phosphorylation of Trpv4 8 0.80 2.46 2.31 99.52
176 INT73427 Localization of P2rx7 24 0.79 8.65 9.87 99.52
177 INT78955 Regulation of Gene_expression of Ptgs2 12 0.62 7.22 6.02 99.52
178 INT134585 Negative_regulation of Cnr2 10 0.43 3.98 6.16 99.50
179 INT50334 Negative_regulation of Cnr1 84 0.58 30.86 51.75 99.50
180 INT82761 Regulation of Positive_regulation of Mapk3 3 0.40 1.34 1.52 99.50
181 INT18755 Positive_regulation of Rvm 79 0.60 60 92.93 99.48
182 INT106720 Positive_regulation of Adcy1 30 0.50 22.05 22.68 99.48
183 INT19771 Positive_regulation of PAG1 69 0.61 75.61 76.88 99.48
184 INT158858 Binding of Mrgprc 1 0.31 0.9 1.28 99.48
185 INT147029 Positive_regulation of Accn4 2 0.19 1.26 1.73 99.48
186 INT45266 Negative_regulation of Nenf 3 0.38 2.46 3.59 99.48
187 INT66531 Gene_expression of Pnoc 88 0.78 22.9 65.11 99.46
188 INT15481 Positive_regulation of asa 13 0.39 6.12 8.24 99.46
189 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61 99.44
190 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14 99.44
191 INT84495 Positive_regulation of Positive_regulation of Ephb1 85 0.70 46.12 54.11 99.44
192 INT57874 Gene_expression of Egr1 113 0.78 68.46 24.95 99.44
193 INT7994 Gene_expression of Lta 113 0.67 69.81 19.59 99.44
194 INT109662 Positive_regulation of Npffr2 2 0.70 2.64 4.02 99.44
195 INT106272 Positive_regulation of Positive_regulation of Mapk14 39 0.70 32.08 24.71 99.44
196 INT259186 Localization of CFM2 1 0.06 0.61 0.47 99.44
197 INT67682 Localization of Bdnf 204 0.81 72.36 88.92 99.42
198 INT233457 Gene_expression of Gpr65 56 0.68 26.57 27.94 99.40
199 INT276855 Positive_regulation of Gene_expression of Gpr65 1 0.61 17.04 16.96 99.40
200 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68 99.40
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