D:Inguinal Hernia

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Disease Term
Synonyms Direct Inguinal Hernia, Direct Inguinal Hernias, Hernia Direct Inguinal, Hernia Indirect Inguinal, HERNIAS DIRECT INGUINAL, Hernias Indirect Inguinal, Hernias Inguinal, Indirect Inguinal Hernia, Indirect Inguinal Hernias, Inguinal Hernia Direct, Inguinal Hernia Indirect
Documents 1179
Hot Single Events 17
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Inguinal Hernia. They are ordered first by their relevance to Inguinal Hernia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT356231 Binding of Gabrb3 and Gad1 1 0.32 1.25 0.23 41.28
2 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9 5.00
3 INT356233 Slc32a1 Positive_regulation of Gabrg1 1 0.17 1.6 1.44 5.00
4 INT356235 SLC32A1 Regulation of Localization of Gabrg1 1 0.10 1.21 0.7 5.00
5 INT356232 Slc32a1 Regulation of Localization of Gabrg1 1 0.10 1.21 0.7 5.00
6 INT174820 IL6 Positive_regulation of VEGFA 1 0.20 3.32 0.12 5.00
7 INT174821 VEGFA Positive_regulation of Gene_expression of IL6 1 0.20 3.13 0.12 5.00
8 INT277890 Binding of Ids and Tas2r111-ps2 1 0.08 0.5 0.09 5.00
9 INT277889 Regulation of Binding of Ids and Tas2r111-ps2 1 0.09 0.5 0.09 5.00
10 INT310674 Positive_regulation of Binding of ARSB and ELF3 1 0.07 2.46 0.05 5.00
11 INT310675 Binding of ARSB and ELF3 1 0.06 2.4 0.05 5.00
12 INT277892 IDS Regulation of Ids 1 0.18 0.41 0 5.00
13 INT287088 Binding of EEC1 and Vamp3 1 0.09 1.02 0 5.00
14 INT277891 Binding of TPBG and M6pr-ps 1 0.02 0.06 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Inguinal Hernia. They are ordered first by their pain relevance and then by number of times they were reported in Inguinal Hernia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 100.00
2 INT214 Localization of AVP 370 0.81 208.51 91.09 99.04
3 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 98.92
4 INT158 Localization of Prl 2431 0.81 378.96 952.2 98.92
5 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69 97.88
6 INT81216 Binding of RPL3P4 2 0.33 0.34 1.18 96.12
7 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 94.68
8 INT22454 Regulation of Crp 213 0.62 160.67 49.24 94.60
9 INT96637 Gene_expression of Gad2 21 0.76 8.15 9.53 94.36
10 INT162 Regulation of Prl 794 0.62 165.01 322.24 92.96
11 INT37835 Negative_regulation of CPP 61 0.51 31.34 18.57 92.88
12 INT253 Regulation of PRL 184 0.62 47.27 65.79 90.00
13 INT9033 Positive_regulation of Pcbd1 14 0.39 3.88 0.86 86.60
14 INT25667 Localization of pcp 9 0.65 2.68 5.82 85.20
15 INT4686 Gene_expression of Cys1 32 0.66 36.24 2.49 83.68
16 INT84248 Gene_expression of MPEG1 5 0.48 3.38 0.66 83.52
17 INT10893 Binding of VWF 27 0.47 25.02 2.82 80.08
18 INT45510 Binding of Scn8a 4 0.31 3.89 0.25 79.52
19 INT9660 Regulation of TNF 363 0.62 312.94 139.99 75.04
20 INT17489 Regulation of F13A1 28 0.45 15.79 4.93 75.00
21 INT14946 Binding of SPARCL1 5 0.31 6.57 1.29 75.00
22 INT101892 Gene_expression of PIM1 10 0.65 7.19 0.85 74.20
23 INT68187 Gene_expression of TNNT2 21 0.67 10.22 1.64 74.04
24 INT60196 Binding of FOS 33 0.47 13.11 6.95 73.24
25 INT116728 Negative_regulation of ARSH 9 0.13 9.67 0.27 72.36
26 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 71.12
27 INT11307 Negative_regulation of pcp 30 0.48 7.86 11.53 70.92
28 INT2139 Negative_regulation of Cea 55 0.43 43.59 9.14 69.68
29 INT105993 Gene_expression of IDS 26 0.78 10.83 2.41 69.40
30 INT29020 Positive_regulation of pcp 18 0.45 3.5 6.39 69.12
31 INT57592 Negative_regulation of TAs 17 0.33 9.49 4.51 68.52
32 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 67.76
33 INT15054 Gene_expression of Mme 48 0.77 42.52 10.63 67.76
34 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97 66.16
35 INT9900 Positive_regulation of Vwf 80 0.69 51.85 18.13 66.16
36 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13 66.16
37 INT67379 Positive_regulation of Cd34 38 0.58 26.18 3.28 66.16
38 INT134628 Gene_expression of Flt4 9 0.48 7.52 1.94 66.16
39 INT196002 Positive_regulation of Flt4 4 0.22 3.51 0.37 66.16
40 INT196007 Positive_regulation of FLT4 2 0.56 5.44 0.08 66.16
41 INT49706 Positive_regulation of TNNT2 22 0.69 12.65 1.56 64.64
42 INT59795 Regulation of Tfrc 5 0.43 4.43 1.48 63.36
43 INT14009 Gene_expression of Sst 66 0.77 19.6 37.3 62.60
44 INT79502 Gene_expression of Pvalb 26 0.78 2.83 7.46 62.60
45 INT196003 Regulation of Cd34 4 0.30 3.38 0.5 61.16
46 INT196006 Regulation of FLT4 2 0.25 2.24 0.27 60.80
47 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 58.12
48 INT120011 Localization of MIF 6 0.58 5.72 2.6 58.00
49 INT3403 Positive_regulation of BCAR1 18 0.63 18.95 3.23 55.48
50 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 55.16
51 INT204254 Localization of KIT 8 0.73 6.78 0.61 53.84
52 INT83442 Negative_regulation of MIF 18 0.57 9.51 5.12 52.28
53 INT163290 Binding of MIF 9 0.31 7.57 2.8 52.28
54 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 50.00
55 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 50.00
56 INT18894 Gene_expression of CPP 44 0.77 23.05 23.05 50.00
57 INT144689 Regulation of RCT 49 0.53 25.91 9.6 50.00
58 INT23647 Negative_regulation of CDA 3 0.38 1.48 0.08 50.00
59 INT161203 Gene_expression of PCSK7 6 0.65 0.92 0 50.00
60 INT117754 Gene_expression of NHS 34 0.57 9.27 3.28 41.48
61 INT356219 Binding of Gabrb3 1 0.29 1.25 0.23 41.28
62 INT180240 Binding of Gad1 7 0.47 2.99 0.86 40.40
63 INT279349 Localization of IDUA 7 0.76 4.97 0.07 37.16
64 INT4144 Gene_expression of SHBG 64 0.68 39.94 6.08 36.96
65 INT281255 Positive_regulation of Negative_regulation of CDY1 1 0.28 1.64 0 35.60
66 INT281257 Positive_regulation of Positive_regulation of DAZ1 1 0.16 1.58 0 35.60
67 INT281252 Positive_regulation of DAZ1 1 0.16 1.56 0 33.68
68 INT277255 Transcription of Satb2 1 0.69 0.46 0 33.68
69 INT281258 Negative_regulation of CDY1 1 0.23 1.61 0 32.88
70 INT277254 Negative_regulation of Satb2 1 0.43 3.26 0.04 30.64
71 INT200806 Binding of EEC1 6 0.39 4.24 0.29 30.08
72 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 25.00
73 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 20.04
74 INT14397 Gene_expression of Serpinc1 27 0.46 14.54 3.32 20.04
75 INT95652 Gene_expression of Krt20 54 0.61 53.69 3.31 19.12
76 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
77 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 5.00
78 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
79 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
80 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 5.00
81 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
82 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
83 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
84 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 5.00
85 INT6354 Localization of Gabrg1 321 0.74 41.41 186.74 5.00
86 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
87 INT6323 Positive_regulation of Gabrg1 213 0.70 45.08 124.34 5.00
88 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
89 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
90 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
91 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
92 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 5.00
93 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 5.00
94 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
95 INT7898 Gene_expression of Homer1 123 0.78 31.52 53.67 5.00
96 INT16850 Negative_regulation of Localization of Gabrg1 73 0.51 8.28 47.89 5.00
97 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 5.00
98 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 5.00
99 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 5.00
100 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 5.00
101 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
102 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 5.00
103 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 5.00
104 INT86437 Binding of IL6 154 0.48 121.22 29.3 5.00
105 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18 5.00
106 INT6855 Binding of NCOR2 71 0.41 15.64 28.96 5.00
107 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54 5.00
108 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 5.00
109 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
110 INT7899 Positive_regulation of Gene_expression of Homer1 41 0.70 7.29 25.98 5.00
111 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 5.00
112 INT27933 Gene_expression of NCOR2 65 0.72 31.35 24.23 5.00
113 INT35716 Positive_regulation of NCOR2 45 0.60 18 23.54 5.00
114 INT1704 Positive_regulation of PCa 68 0.59 34.92 23.36 5.00
115 INT45437 Localization of Acot1 84 0.79 17.37 22.18 5.00
116 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73 5.00
117 INT33327 Positive_regulation of Gene_expression of Gabrg1 39 0.69 9.68 18.82 5.00
118 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 5.00
119 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
120 INT22143 Gene_expression of Gad1 35 0.76 14.4 15.4 5.00
121 INT16266 Gene_expression of Chat 80 0.67 16.14 15.01 5.00
122 INT148639 Gene_expression of Uchl1 30 0.59 16.76 11.54 5.00
123 INT6510 Gene_expression of AFP 130 0.78 119.2 9.19 5.00
124 INT22083 Regulation of Pth 55 0.62 22.32 8.9 5.00
125 INT591 Negative_regulation of Serpinc1 44 0.57 31.73 8.82 5.00
126 INT45812 Protein_catabolism of Gabrg1 12 0.79 1.93 8.76 5.00
127 INT2921 Positive_regulation of F8 53 0.59 41.56 8.56 5.00
128 INT3983 Positive_regulation of Acot1 30 0.68 5.83 8.34 5.00
129 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27 5.00
130 INT24891 Gene_expression of SYP 55 0.75 45.76 7.53 5.00
131 INT49751 Negative_regulation of Positive_regulation of PTGS1 12 0.45 4.73 7.23 5.00
132 INT114201 Gene_expression of Slc32a1 8 0.78 14.2 7.21 5.00
133 INT16268 Binding of HTR3A 15 0.47 7.38 7.18 5.00
134 INT69561 Positive_regulation of GSTM1 23 0.50 5.69 6.36 5.00
135 INT9118 Gene_expression of Ceacam1 37 0.75 17.19 6.12 5.00
136 INT20899 Negative_regulation of GNAI1 12 0.57 4.24 6.07 5.00
137 INT25123 Negative_regulation of COL7A1 42 0.58 19.98 5.96 5.00
138 INT104330 Negative_regulation of CDKN1A 57 0.58 39.93 5.88 5.00
139 INT20673 Binding of CDS1 18 0.31 1.96 5.72 5.00
140 INT23598 Binding of SCN5A 32 0.40 16 5.35 5.00
141 INT10889 Gene_expression of F8 60 0.78 41.36 5.06 5.00
142 INT156794 Gene_expression of CISH 41 0.58 23.09 5.03 5.00
143 INT170604 Negative_regulation of Gene_expression of GOPC 50 0.35 12.71 4.51 5.00
144 INT47044 Positive_regulation of ORM1 5 0.68 0.58 4.46 5.00
145 INT6021 Binding of PRL 18 0.48 12.55 4.3 5.00
146 INT80421 Positive_regulation of IFI27 26 0.65 15.32 3.93 5.00
147 INT9500 Negative_regulation of Ceacam1 26 0.58 6.89 3.91 5.00
148 INT149259 Gene_expression of RCT 38 0.67 15.73 3.87 5.00
149 INT21406 Negative_regulation of Gene_expression of IgG 20 0.41 9.36 3.58 5.00
150 INT79477 Binding of HLA-DMA 19 0.26 13.78 3.47 5.00
151 INT4003 Positive_regulation of Gene_expression of IGHG3 31 0.46 20.38 3.16 5.00
152 INT134086 Positive_regulation of Slc32a1 3 0.65 2.11 3.03 5.00
153 INT24904 Negative_regulation of PAPPA 13 0.57 9.93 2.74 5.00
154 INT101246 Gene_expression of Gata6 6 0.68 3.03 2.68 5.00
155 INT188756 Positive_regulation of AGRP 43 0.60 23.67 2.51 5.00
156 INT22082 Localization of Ceacam1 13 0.80 2.44 2.48 5.00
157 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 5.00
158 INT29228 Negative_regulation of Binding of NCOR2 4 0.02 0.62 2.47 5.00
159 INT90566 Positive_regulation of Gene_expression of Gad1 5 0.48 1.46 2.42 5.00
160 INT12033 Binding of PLOD1 15 0.48 8.04 2.3 5.00
161 INT89519 Negative_regulation of COL1A2 10 0.36 6.26 2.17 5.00
162 INT47543 Positive_regulation of Chrm3 11 0.38 5.23 2.17 5.00
163 INT22282 Positive_regulation of Chat 8 0.67 2.82 2.12 5.00
164 INT68829 Binding of ELF3 14 0.47 7.96 2 5.00
165 INT69702 Positive_regulation of PMAIP1 7 0.35 8.81 1.98 5.00
166 INT351284 Regulation of Localization of AP1M2 1 0.04 0.85 1.9 5.00
167 INT351285 Localization of AP1M2 1 0.07 0.79 1.89 5.00
168 INT94934 Negative_regulation of COX1 3 0.57 3.27 1.75 5.00
169 INT356220 Binding of Slc32a1 1 0.32 1.48 1.74 5.00
170 INT222970 Localization of Chat 6 0.73 0.96 1.66 5.00
171 INT161371 Gene_expression of Glul 7 0.61 2.44 1.58 5.00
172 INT223091 Gene_expression of ELF3 45 0.62 17.9 1.56 5.00
173 INT109881 Positive_regulation of Gene_expression of F8 11 0.47 12.97 1.54 5.00
174 INT7033 Binding of FSHR 19 0.37 6.66 1.52 5.00
175 INT64952 Binding of HLA-DQA2 11 0.10 7.23 1.39 5.00
176 INT48269 Negative_regulation of FANCB 16 0.56 5.34 1.38 5.00
177 INT114199 Positive_regulation of Gene_expression of Slc32a1 2 0.44 1.71 1.35 5.00
178 INT38990 Negative_regulation of IDUA 12 0.59 5.04 1.33 5.00
179 INT161648 Gene_expression of TAs 9 0.58 3.57 1.28 5.00
180 INT38989 Gene_expression of IDUA 22 0.78 16.99 1.26 5.00
181 INT15896 Gene_expression of FANCB 18 0.65 6.44 1.18 5.00
182 INT227604 Transcription of Chat 4 0.52 1.01 1.08 5.00
183 INT105991 Negative_regulation of IDS 12 0.38 6.31 1.04 5.00
184 INT134822 Gene_expression of Gja1 18 0.72 4.2 1 5.00
185 INT200462 Binding of IDS 13 0.31 4.95 1 5.00
186 INT69134 Positive_regulation of MPEG1 9 0.26 5.95 0.97 5.00
187 INT22081 Regulation of Ceacam1 8 0.23 4.11 0.95 5.00
188 INT356228 Positive_regulation of Slc18a3 1 0.35 0.9 0.94 5.00
189 INT53197 Binding of Thy1 5 0.36 1.38 0.93 5.00
190 INT251459 Binding of Ie 18 0.20 6.62 0.75 5.00
191 INT287087 Localization of EEC1 2 0.61 1.6 0.72 5.00
192 INT200438 Negative_regulation of Gene_expression of SCN5A 6 0.36 1.93 0.71 5.00
193 INT242541 Regulation of Gene_expression of Chat 3 0.43 0.67 0.67 5.00
194 INT47553 Gene_expression of ARSH 11 0.42 4.93 0.65 5.00
195 INT84250 Positive_regulation of IDUA 8 0.56 15.89 0.62 5.00
196 INT137221 Gene_expression of Sh2d1b2 6 0.47 1.99 0.6 5.00
197 INT346406 Gene_expression of Mns1 2 0.12 0.27 0.6 5.00
198 INT137222 Positive_regulation of Sh2d1b2 5 0.30 1.26 0.6 5.00
199 INT356226 Positive_regulation of Transcription of Acot1 1 0.06 0.28 0.54 5.00
200 INT356223 Transcription of Acot1 1 0.07 0.28 0.54 5.00
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