D:Insect Bites And Stings

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Disease Term
Synonyms Bite Insect, Bites Insect, Insect Bite, Insect Bites, Insect Bites Stings, Insect Sting, INSECT STINGS, Sting Insect, Stings Insect
Documents 126
Hot Single Events 11
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Insect Bites And Stings. They are ordered first by their relevance to Insect Bites And Stings and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT89500 Nos2 Positive_regulation of Il6 1 0.04 1.07 0.35 69.28
2 INT89501 Il6 Positive_regulation of Ptgs2 1 0.01 1.07 0.35 68.88
3 INT89505 Nos2 Positive_regulation of Ptgs2 1 0.05 1.07 0.34 68.88
4 INT89502 Positive_regulation of Nos2 Positive_regulation of Ptgs2 1 0.05 1.07 0.34 68.88
5 INT186373 Il6 Positive_regulation of Gene_expression of Il17a 2 0.14 1.52 0.42 5.00
6 INT297423 Gene_expression of Il4 Regulation of Ppara 1 0.07 1.19 0.38 5.00
7 INT297424 Gene_expression of Stat6 Regulation of Ppara 1 0.17 1.19 0.38 5.00
8 INT297425 Il4 Regulation of Ppara 1 0.07 1.17 0.38 5.00
9 INT297426 Stat6 Regulation of Ppara 1 0.17 1.19 0.38 5.00
10 INT347517 Binding of Tbxa2r and ST7L 1 0.00 0 0.32 5.00
11 INT297428 Lvs Positive_regulation of Gene_expression of Il13 1 0.06 1.2 0.3 5.00
12 INT297422 Lvs Positive_regulation of Gene_expression of Il4 1 0.04 1.2 0.3 5.00
13 INT297427 Flg Positive_regulation of Gene_expression of Il13 1 0.11 1.2 0.3 5.00
14 INT101810 Binding of NFE2L2 and KEAP1 7 0.53 4.12 0.29 5.00
15 INT316538 Lvs Positive_regulation of Gene_expression of Il17a 1 0.30 1.3 0.21 5.00
16 INT193215 Binding of CYSLTR1 and CYSLTR2 2 0.09 1.7 0.21 5.00
17 INT326464 KNG1 Positive_regulation of SERPING1 1 0.19 1.53 0.18 5.00
18 INT347518 Regulation of Binding of Tbxa2r and ST7L 1 0.00 0 0.17 5.00
19 INT316535 Il23a Regulation of Il12a 1 0.07 1.15 0.15 5.00
20 INT347462 Binding of CYSLTR1 and ST7L 1 0.00 0.1 0.13 5.00
21 INT347515 Binding of GP1BA and Vwf 1 0.01 0.19 0.11 5.00
22 INT306241 Ins1 Negative_regulation of Gene_expression of PCK1 1 0.00 0.91 0.08 5.00
23 INT316539 Il17a Positive_regulation of Gene_expression of Lvs 1 0.22 1.02 0.08 5.00
24 INT186860 MIR181A2HG Regulation of Cd86 1 0.02 1.05 0.07 5.00
25 INT186814 MIR181A2HG Regulation of ICAM1 1 0.01 1.05 0.07 5.00
26 INT306238 Tead1 Regulation of Ins1 1 0.00 1.04 0.05 5.00
27 INT347465 Binding of PLEK and ST7L 1 0.01 0 0.04 5.00
28 INT347464 Binding of WDTC1 and ST7L 1 0.00 0 0.04 5.00
29 INT205862 CNTN2 Positive_regulation of TNF 1 0.01 0.08 0.04 5.00
30 INT347463 Binding of PTAFR and ST7L 1 0.00 0 0.04 5.00
31 INT347514 Binding of CYSLTR1 and Ltc4s 1 0.01 0.58 0.03 5.00
32 INT347516 Binding of CYSLTR2 and Ltc4s 1 0.01 0.4 0.03 5.00
33 INT246061 KEAP1 Regulation of Positive_regulation of NFE2L2 1 0.34 0 0 5.00
34 INT205863 Binding of FDPS and HTLVR 1 0.00 0.07 0 5.00
35 INT246058 Binding of KEAP1 and Positive_regulation of NFE2L2 1 0.38 0 0 5.00
36 INT316537 Binding of Tlr1 and Il23a 1 0.12 0.78 0 5.00
37 INT316536 Binding of Tlr2 and Il23a 1 0.11 0.78 0 5.00
38 INT205875 Binding of FDPS and G4 1 0.02 0.13 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Insect Bites And Stings. They are ordered first by their pain relevance and then by number of times they were reported in Insect Bites And Stings. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT8798 Positive_regulation of Csrp1 61 0.69 63.86 14.14 98.04
2 INT61366 Positive_regulation of NFASC 16 0.26 13.75 4.11 97.72
3 INT3821 Negative_regulation of C1s 13 0.42 7.89 2.08 97.04
4 INT326468 Regulation of Negative_regulation of TRGC1 1 0.19 2.8 0.17 96.88
5 INT46383 Negative_regulation of TRGC1 42 0.55 44.03 6.2 96.60
6 INT67183 Binding of Serpinb1a 4 0.37 4 1.77 92.80
7 INT9077 Regulation of Tbxa2r 13 0.45 5.49 3.75 88.60
8 INT16618 Negative_regulation of SERPING1 81 0.59 86.28 7.17 85.52
9 INT118054 Regulation of ARMC9 23 0.34 11.32 1.06 84.56
10 INT117316 Positive_regulation of GZMA 3 0.59 3.11 0.15 83.84
11 INT194298 Gene_expression of DHPS 1 0.62 8.84 0.37 81.52
12 INT57881 Binding of Tead1 2 0.25 1.63 0.7 79.84
13 INT2429 Negative_regulation of Mpo 128 0.59 93.76 39.57 77.92
14 INT194299 Binding of DHPS 1 0.39 2.22 0.17 77.60
15 INT57549 Gene_expression of GNPTAB 49 0.65 57.5 9.05 76.16
16 INT156672 Localization of SERPING1 10 0.74 12.15 1.25 75.76
17 INT9749 Positive_regulation of sar 25 0.50 9.96 2.09 75.00
18 INT186121 Gene_expression of Agxt 6 0.65 2.77 0.39 75.00
19 INT11860 Positive_regulation of Positive_regulation of sar 3 0.32 1.51 0.62 75.00
20 INT46302 Binding of sar 6 0.36 2.37 0.7 75.00
21 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 74.44
22 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 74.44
23 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67 74.44
24 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 74.44
25 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 74.44
26 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 74.44
27 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 74.44
28 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 74.44
29 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 74.44
30 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07 74.44
31 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18 74.44
32 INT85535 Negative_regulation of Gene_expression of Ptgs2 27 0.51 16.04 10.01 74.44
33 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 73.00
34 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 71.84
35 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 68.04
36 INT61223 Positive_regulation of Negative_regulation of ACE 6 0.49 5.92 1.37 67.00
37 INT326469 Positive_regulation of Negative_regulation of AGTR2 1 0.09 2.96 0.16 67.00
38 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 66.72
39 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 66.68
40 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 65.96
41 INT209345 Negative_regulation of AGTR2 5 0.17 4.83 0.2 64.92
42 INT3880 Negative_regulation of Serping1 54 0.58 37.19 4.75 63.60
43 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 62.08
44 INT77281 Negative_regulation of HIVEP1 132 0.49 102.78 5.36 60.32
45 INT233322 Negative_regulation of Localization of HIVEP1 4 0.10 6.1 0.57 60.32
46 INT167820 Regulation of Gene_expression of Tcm 2 0.39 0.06 0.03 60.32
47 INT62487 Localization of HIVEP1 35 0.73 36.24 2.72 60.00
48 INT169525 Positive_regulation of Serpinb1a 4 0.44 6.48 1.24 59.84
49 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 59.40
50 INT117204 Gene_expression of Tcm 39 0.58 10.58 4.88 58.80
51 INT172479 Positive_regulation of NFE2L2 74 0.70 35.22 0.79 56.24
52 INT47885 Gene_expression of Max 5 0.65 0.54 1.84 51.84
53 INT30531 Gene_expression of C2 15 0.66 5.5 1.99 51.68
54 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 48.12
55 INT3911 Gene_expression of TNFAIP1 29 0.65 21.68 1.85 41.44
56 INT304694 Binding of Lvs 4 0.15 3.71 0.16 37.28
57 INT764 Gene_expression of OLAH 25 0.67 25.58 8.07 35.20
58 INT197568 Regulation of NFE2L2 17 0.59 7.85 0.15 30.96
59 INT73595 Positive_regulation of BAX 61 0.61 56.97 7.82 30.28
60 INT238507 Regulation of Regulation of BCL2 3 0.44 5.14 0.16 30.16
61 INT84685 Regulation of BCL2 67 0.60 72.96 6.65 29.08
62 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31 27.40
63 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 25.00
64 INT11859 Positive_regulation of Tbxa2r 44 0.61 22.62 9.61 25.00
65 INT34009 Binding of Tbxa2r 33 0.36 17.98 8.01 25.00
66 INT15996 Binding of Ltc4s 9 0.35 5.66 1.64 25.00
67 INT326185 Binding of ST7L 2 0.08 1.46 1 25.00
68 INT131609 Binding of Tbxa2r 3 0.24 1.33 0.55 25.00
69 INT347468 Protein_catabolism of Tbxa2r 1 0.19 0.24 0.05 25.00
70 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92 23.68
71 INT274806 Binding of NDST1 1 0.36 1.39 0.2 23.32
72 INT14559 Gene_expression of Igf1 254 0.78 112 34.17 22.80
73 INT107386 Negative_regulation of AGTR1 37 0.55 35.94 5.15 22.28
74 INT163253 Binding of Flg 3 0.31 3.6 0.32 22.24
75 INT70962 Positive_regulation of SERPING1 33 0.69 27.32 2.14 6.40
76 INT23598 Binding of SCN5A 32 0.40 16 5.35 5.12
77 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
78 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
79 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
80 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
81 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
82 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
83 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
84 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
85 INT1114 Localization of Ins1 748 0.80 192.95 165.48 5.00
86 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81 5.00
87 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
88 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
89 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 5.00
90 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 5.00
91 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
92 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 5.00
93 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 5.00
94 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
95 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
96 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36 5.00
97 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 5.00
98 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 5.00
99 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 5.00
100 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 5.00
101 INT7134 Localization of KNG1 127 0.79 65.73 67.97 5.00
102 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9 5.00
103 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 5.00
104 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 5.00
105 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 5.00
106 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
107 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 5.00
108 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
109 INT2276 Regulation of Ins1 234 0.61 103.78 54.05 5.00
110 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 5.00
111 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 5.00
112 INT7093 Negative_regulation of CYP2B6 146 0.58 37.3 48.39 5.00
113 INT100939 Gene_expression of Il13 176 0.73 125.1 43.38 5.00
114 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
115 INT13354 Transcription of TNF 108 0.72 85.81 42.32 5.00
116 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
117 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24 5.00
118 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
119 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 5.00
120 INT20380 Gene_expression of Il5 172 0.78 104.75 34.78 5.00
121 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 5.00
122 INT17381 Gene_expression of Tbxa2r 146 0.78 65.01 34.15 5.00
123 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 5.00
124 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 5.00
125 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
126 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 5.00
127 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 5.00
128 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75 5.00
129 INT16814 Negative_regulation of COX5A 74 0.57 33.72 28.63 5.00
130 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55 5.00
131 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
132 INT135411 Gene_expression of Il23a 76 0.72 72.87 26.15 5.00
133 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6 5.00
134 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05 5.00
135 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26 5.00
136 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22 5.00
137 INT150022 Positive_regulation of Il17a 69 0.64 70.04 21.87 5.00
138 INT78057 Localization of Tlr4 140 0.77 67.75 21.72 5.00
139 INT60690 Positive_regulation of Gene_expression of Il12a 69 0.63 41.41 20.85 5.00
140 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66 5.00
141 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
142 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 5.00
143 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 5.00
144 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 5.00
145 INT12950 Gene_expression of Cat 85 0.75 35.94 15.76 5.00
146 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49 5.00
147 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31 5.00
148 INT180497 Binding of MRI1 45 0.42 28.35 14.77 5.00
149 INT100938 Positive_regulation of Il13 47 0.69 42.11 14.36 5.00
150 INT16321 Gene_expression of Cd3e 111 0.72 49.9 14.21 5.00
151 INT59870 Gene_expression of F3 51 0.65 51.83 14.01 5.00
152 INT53948 Regulation of Gene_expression of Cpox 40 0.51 20.97 13.87 5.00
153 INT161515 Positive_regulation of Gene_expression of Il17a 50 0.64 41.52 13.82 5.00
154 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 5.00
155 INT120901 Positive_regulation of Gene_expression of Il13 36 0.57 31.63 13.36 5.00
156 INT87235 Negative_regulation of Il4 54 0.48 31.51 13.15 5.00
157 INT62441 Gene_expression of ABCC1 56 0.78 21.01 12.93 5.00
158 INT54763 Binding of Il6 82 0.48 63.27 12.89 5.00
159 INT174838 Localization of INCENP 80 0.64 19.05 12.89 5.00
160 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8 5.00
161 INT69436 Negative_regulation of Gene_expression of ROS1 81 0.38 46.58 12.22 5.00
162 INT112003 Localization of ROS1 94 0.73 66.32 12.16 5.00
163 INT69158 Localization of IL4 48 0.71 31.3 11.98 5.00
164 INT3699 Gene_expression of H2-Ab1 24 0.74 12.06 11.82 5.00
165 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 5.00
166 INT24816 Binding of CD40LG 68 0.47 45.48 11.56 5.00
167 INT111223 Positive_regulation of HMOX1 47 0.70 39.14 10.92 5.00
168 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 5.00
169 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75 5.00
170 INT18412 Binding of PLEK 49 0.47 17.82 10.72 5.00
171 INT133172 Gene_expression of Il12b 98 0.75 52.16 10.68 5.00
172 INT135022 Gene_expression of Cd14 79 0.76 36.37 10.63 5.00
173 INT4806 Localization of TPSAB1 29 0.80 5.05 10.52 5.00
174 INT94784 Binding of ROS1 113 0.40 71.57 10.26 5.00
175 INT160563 Localization of Il17a 34 0.74 26.53 10.24 5.00
176 INT140338 Negative_regulation of Gene_expression of Il17a 34 0.46 23.82 9.87 5.00
177 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78 5.00
178 INT18145 Positive_regulation of Gene_expression of Tbxa2r 30 0.66 18.91 9.52 5.00
179 INT97439 Positive_regulation of Il5 46 0.60 25.6 9.47 5.00
180 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27 5.00
181 INT20664 Binding of ACE 60 0.48 35.27 9.16 5.00
182 INT14301 Binding of CSF2 82 0.48 67.95 8.98 5.00
183 INT20371 Gene_expression of Cd8a 125 0.60 67.59 8.97 5.00
184 INT186273 Negative_regulation of Il13 33 0.46 22.88 8.65 5.00
185 INT15529 Gene_expression of GCG 51 0.75 18.55 8.35 5.00
186 INT20348 Negative_regulation of Tbxa2r 47 0.59 19.88 7.68 5.00
187 INT5409 Negative_regulation of G6pd 33 0.57 29.21 7.64 5.00
188 INT131359 Positive_regulation of Gene_expression of Cd4 40 0.58 22.43 7.53 5.00
189 INT1123 Positive_regulation of CD79A 74 0.70 51.96 7.14 5.00
190 INT11858 Localization of Tbxa2r 39 0.80 21.24 7.09 5.00
191 INT93046 Positive_regulation of Gene_expression of Hand2 27 0.47 24.54 7.01 5.00
192 INT138799 Regulation of Gene_expression of Ppara 40 0.60 29.42 6.89 5.00
193 INT68653 Negative_regulation of JUN 34 0.58 14.27 6.56 5.00
194 INT1926 Positive_regulation of PLAT 54 0.66 31.42 6.49 5.00
195 INT228469 Negative_regulation of Il17a 19 0.54 18.76 6.43 5.00
196 INT9695 Negative_regulation of Csf2 41 0.57 31.65 6.28 5.00
197 INT83451 Positive_regulation of Gene_expression of CD40LG 26 0.60 22.81 6.25 5.00
198 INT14258 Regulation of TSPO 32 0.60 10.16 6.24 5.00
199 INT91657 Negative_regulation of IL18 20 0.48 15.97 6.12 5.00
200 INT14238 Positive_regulation of Cd69 19 0.60 17.75 6.07 5.00
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