D:Internal Fibrosis

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Disease Term
Synonyms Hepatic Fibrosis, Kidney Fibrosis, Liver Fibrosis, Pulmonary Fibrosis, RENAL FIBROSIS
Documents 33
Hot Single Events 89
Hot Interactions 9

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Internal Fibrosis. They are ordered first by their relevance to Internal Fibrosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT305001 Binding of ACAN and TNFAIP6 1 0.28 1.22 0.14 99.70
2 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34 94.24
3 INT270731 Binding of AGTR1 and ACE 1 0.02 0.67 0.09 94.24
4 INT167757 Binding of Enpp2 and Dmbx1 1 0.22 0.33 0.13 88.64
5 INT185818 SPP1 Positive_regulation of Gene_expression of COL7A1 1 0.10 0.82 0.28 87.24
6 INT241777 Negative_regulation of Binding of AVP and TRGV9 1 0.10 0.75 0.13 85.92
7 INT241780 Binding of AVP and TRGV9 1 0.12 2.41 0.35 85.60
8 INT269211 SNAI1 Positive_regulation of Gene_expression of CDH1 1 0.40 0.73 0.04 83.28
9 INT333393 CFD Positive_regulation of Gene_expression of Timp1 1 0.07 0.82 0.16 81.92
10 INT269214 SNAI1 Positive_regulation of Positive_regulation of CDH1 1 0.35 0.71 0.04 77.44
11 INT241772 AVP Positive_regulation of ADCY1 1 0.09 1.08 0.15 76.64
12 INT305002 Binding of HIF1A and SERPINE1 1 0.07 1.17 0.11 75.20
13 INT355503 Positive_regulation of SCN10A Positive_regulation of Localization of NPY 1 0.17 1.32 0.22 74.04
14 INT330120 Bdkrb2 Regulation of Bdkrb1 1 0.19 1.26 0.38 73.88
15 INT333396 CFD Positive_regulation of Bcl2l1 1 0.05 0.98 0.13 73.40
16 INT153289 Binding of Lpar1 and Gpr87 2 0.29 1.19 0.67 71.28
17 INT153288 Binding of Lpar1 and Lpar6 2 0.31 0.78 0.36 71.28
18 INT305003 HIF1A Regulation of SERPINE1 1 0.11 2.3 0.19 69.04
19 INT333397 CFD Negative_regulation of Gene_expression of Nos2 1 0.04 0.8 0.22 56.16
20 INT349646 Eif2ak1 Regulation of Gene_expression of Hmox1 1 0.00 0.78 0.2 55.20
21 INT333394 CFD Negative_regulation of Gene_expression of Cat 1 0.03 0.79 0.22 54.96
22 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61 51.00
23 INT185804 MMP2 Positive_regulation of SPP1 1 0.15 0.88 0.37 45.64
24 INT185798 SPP1 Positive_regulation of Gene_expression of MMP2 1 0.26 0.87 0.37 45.64
25 INT329839 Negative_regulation of Tnfsf13b Negative_regulation of Gene_expression of Ighm 1 0.05 2.28 0.06 45.04
26 INT299158 Binding of Lgals3 and Renbp 1 0.00 0.64 0.11 43.04
27 INT269838 Binding of Hsp90b1 and Tlr2 1 0.26 1.75 0.03 40.64
28 INT185800 SPP1 Negative_regulation of Gene_expression of MMP1 1 0.26 1.03 0.49 39.92
29 INT185811 SPP1 Positive_regulation of MMP3 1 0.14 0.83 0.38 39.40
30 INT185814 Binding of MMP3 and SPP1 1 0.15 0.83 0.38 39.40
31 INT185793 SPP1 Positive_regulation of COL1A2 1 0.16 0.33 0.16 37.44
32 INT355504 ANGPT2 Positive_regulation of CYBB 1 0.01 0.81 0.18 35.84
33 INT185808 SPP1 Positive_regulation of TIMP1 1 0.64 0.33 0.16 35.68
34 INT185795 MMP7 Positive_regulation of SPP1 1 0.38 0.81 0.37 35.52
35 INT185807 SPP1 Positive_regulation of MMP7 1 0.56 0.79 0.36 32.64
36 INT349652 Positive_regulation of Hmox1 Negative_regulation of Positive_regulation of Itk 1 0.01 0.85 0.25 25.80
37 INT349653 Nfe2l2 Positive_regulation of Itk 1 0.00 0.79 0.22 23.92
38 INT333398 CFD Negative_regulation of Gene_expression of Pdgfa 1 0.02 0.64 0.3 21.08
39 INT330124 Positive_regulation of Bdkrb1 Positive_regulation of RT1-O2-ps 1 0.02 1.97 1.3 5.00
40 INT185802 Binding of MMP7 and SPP1 1 0.33 1.71 0.68 5.00
41 INT185809 Binding of PDX1 and SPP1 1 0.02 1.69 0.57 5.00
42 INT313223 Binding of Cx3cr1 and Mcpt1 1 0.06 0.99 0.56 5.00
43 INT313224 Negative_regulation of Binding of Cx3cr1 and Mcpt1 1 0.07 0.99 0.56 5.00
44 INT291616 Cby1 Positive_regulation of Gene_expression of Smad7 1 0.00 0.79 0.38 5.00
45 INT133307 Binding of CD44 and SPP1 5 0.26 2.6 0.35 5.00
46 INT330122 Agt Positive_regulation of Gene_expression of Agtr1a 1 0.03 0.69 0.34 5.00
47 INT330121 Agtr1a Positive_regulation of Gene_expression of Bdkrb1 1 0.05 0.68 0.34 5.00
48 INT330119 Agt Positive_regulation of Gene_expression of Bdkrb1 1 0.37 0.63 0.34 5.00
49 INT241776 Binding of AVP and Positive_regulation of ADCY1 1 0.06 0.54 0.32 5.00
50 INT185799 Binding of EGFR and SPP1 1 0.19 0.64 0.29 5.00
51 INT185806 Binding of PDX1 and MMP7 1 0.02 0.84 0.28 5.00
52 INT185813 Binding of MMP7 and Positive_regulation of SPP1 1 0.46 0.85 0.28 5.00
53 INT299155 Smcp Negative_regulation of Spp1 1 0.00 0.7 0.22 5.00
54 INT299156 Smcp Negative_regulation of Tnc 1 0.05 0.7 0.22 5.00
55 INT299154 Smcp Negative_regulation of Lgals3 1 0.04 0.69 0.22 5.00
56 INT353285 Prdx2 Regulation of Gene_expression of Col1a2 1 0.02 0.73 0.21 5.00
57 INT349647 Eif2ak1 Positive_regulation of Positive_regulation of Hmox1 1 0.00 1.07 0.2 5.00
58 INT185805 SPP1 Regulation of MMP7 1 0.25 0.38 0.19 5.00
59 INT185816 SPP1 Positive_regulation of Positive_regulation of MMP7 1 0.46 0.36 0.18 5.00
60 INT329841 Il4 Regulation of Hand1 1 0.04 0.87 0.18 5.00
61 INT329843 Il4 Regulation of Hand2 1 0.04 0.87 0.18 5.00
62 INT185803 Binding of MMP11 and SPP1 1 0.06 0.34 0.17 5.00
63 INT185815 Binding of MMP1 and SPP1 1 0.21 0.34 0.17 5.00
64 INT185810 Binding of MMP2 and SPP1 1 0.14 0.34 0.17 5.00
65 INT351565 Binding of LPAR6 and SFXN5 1 0.00 1.1 0.17 5.00
66 INT241774 Binding of AVPR1A and TRGV9 1 0.02 0.48 0.09 5.00
67 INT356379 DMD Positive_regulation of Negative_regulation of Utrn 1 0.54 0.84 0.07 5.00
68 INT313225 Binding of Tec and Gopc 1 0.05 1.21 0.06 5.00
69 INT269210 CDH1 Positive_regulation of Positive_regulation of ITK 1 0.06 0.84 0.06 5.00
70 INT353284 Prdx2 Negative_regulation of Gene_expression of Smad2 1 0.16 0.07 0.05 5.00
71 INT349645 Eif2ak1 Positive_regulation of Hmox1 1 0.00 0.18 0.05 5.00
72 INT349648 Eif2ak1 Positive_regulation of Gene_expression of Hmox1 1 0.00 0.17 0.04 5.00
73 INT353290 Binding of Smad2 and Smad4 1 0.20 0.08 0.04 5.00
74 INT353294 Binding of Smad2 and Smad3 1 0.15 0.08 0.04 5.00
75 INT353295 Binding of Smad3 and Smad4 1 0.17 0.08 0.04 5.00
76 INT353289 Prdx2 Negative_regulation of Positive_regulation of Smad2 1 0.18 0.17 0.04 5.00
77 INT353293 Prdx2 Negative_regulation of Localization of Smad2 1 0.16 0 0.04 5.00
78 INT353287 Prdx2 Positive_regulation of Phosphorylation of Smad7 1 0.22 0.06 0.03 5.00
79 INT353291 Prdx2 Positive_regulation of Smad7 1 0.31 0.06 0.03 5.00
80 INT353286 Prdx2 Positive_regulation of Phosphorylation of Smad2 1 0.24 0.06 0.03 5.00
81 INT353288 Smad7 Negative_regulation of Phosphorylation of Tgif1 1 0.08 0.06 0.03 5.00
82 INT353283 Prdx2 Positive_regulation of Phosphorylation of Tgif1 1 0.10 0.06 0.03 5.00
83 INT353292 Prdx2 Positive_regulation of Tgif1 1 0.10 0.06 0.03 5.00
84 INT241775 AVP Positive_regulation of Gene_expression of AQP2 1 0.08 0.17 0 5.00
85 INT270732 DBP Negative_regulation of SHBG 1 0.00 1.08 0 5.00
86 INT185796 SPP1 Regulation of Gene_expression of COL7A1 1 0.06 0 0 5.00
87 INT241779 AVP Positive_regulation of TRGV9 1 0.17 0.48 0 5.00
88 INT241769 AVP Regulation of Binding of AVPR1A 1 0.11 0.49 0 5.00
89 INT241771 Binding of AVP and AVPR1B 1 0.04 0.49 0 5.00
90 INT269209 SNAI1 Regulation of Gene_expression of LOXL2 1 0.07 1.14 0 5.00
91 INT333395 Binding of CFD and Aes 1 0.03 0.24 0 5.00
92 INT185817 SPP1 Positive_regulation of Gene_expression of TIMP1 1 0.64 0 0 5.00
93 INT241778 AVP Positive_regulation of AVPR1A 1 0.10 1.32 0 5.00
94 INT356377 Dmd Positive_regulation of Negative_regulation of Mib2 1 0.03 0.51 0 5.00
95 INT269213 Binding of SNAI1 and Positive_regulation of Gene_expression of CDH1 1 0.37 1.03 0 5.00
96 INT185801 SPP1 Regulation of Gene_expression of TIMP1 1 0.25 0 0 5.00
97 INT185794 SPP1 Regulation of Gene_expression of MMP1 1 0.16 0 0 5.00
98 INT185812 SPP1 Negative_regulation of MMP1 1 0.26 0 0 5.00
99 INT299157 Binding of Lgals3 and Fn1 1 0.04 0.16 0 5.00
100 INT241768 Binding of AVP and AVPR1A 1 0.08 0.49 0 5.00
101 INT241770 AVP Regulation of Binding of TRGV9 1 0.11 0.49 0 5.00
102 INT241773 AVP Regulation of Binding of AVPR1B 1 0.05 0.49 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Internal Fibrosis. They are ordered first by their pain relevance and then by number of times they were reported in Internal Fibrosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT170854 Gene_expression of CFD 26 0.68 39.77 4.74 100.00
2 INT153277 Gene_expression of Lpar6 2 0.49 1.76 0.61 100.00
3 INT305013 Positive_regulation of Gene_expression of TNFAIP6 1 0.62 1.24 0.15 99.96
4 INT86521 Gene_expression of Lpar1 167 0.78 154.61 80.35 99.88
5 INT123224 Gene_expression of TNFAIP6 12 0.70 7.13 1.21 99.76
6 INT269217 Gene_expression of SNAI1 81 0.76 80.49 2.26 99.76
7 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62 99.68
8 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26 99.68
9 INT88935 Positive_regulation of SPP1 36 0.70 31.07 5.49 99.60
10 INT123223 Binding of TNFAIP6 5 0.35 3.36 1.65 99.58
11 INT65295 Negative_regulation of Bdkrb2 9 0.37 6.36 6.49 99.56
12 INT30517 Negative_regulation of Bdkrb1 16 0.58 16.52 16.88 99.56
13 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18 99.38
14 INT269226 Positive_regulation of ITK 13 0.12 11.23 0.4 98.64
15 INT224442 Negative_regulation of Gene_expression of Pdgfa 2 0.30 2.48 0.5 98.56
16 INT71115 Positive_regulation of Gene_expression of Serpine1 20 0.70 15.32 1.97 98.48
17 INT86560 Localization of Lgals3 5 0.75 7.21 2.23 98.40
18 INT20102 Gene_expression of Serpine1 102 0.78 65.99 12.61 98.20
19 INT96775 Gene_expression of Pdgfa 42 0.54 29.78 15.46 98.16
20 INT39879 Positive_regulation of Gene_expression of Fn1 12 0.41 12.69 0.78 97.96
21 INT86646 Positive_regulation of SCN10A 71 0.69 50.61 13.24 97.92
22 INT142491 Positive_regulation of Positive_regulation of SCN10A 6 0.61 3.48 0.35 97.92
23 INT137614 Gene_expression of Lgals3 70 0.77 66.13 12.53 97.84
24 INT15723 Gene_expression of Fn1 47 0.78 37.59 8.51 97.78
25 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 96.64
26 INT267894 Gene_expression of ITK 13 0.57 9.71 0.9 95.88
27 INT8067 Negative_regulation of Binding of AGT 12 0.25 10.33 1.39 95.56
28 INT269229 Regulation of ITK 3 0.10 3.62 0.05 95.40
29 INT8065 Binding of AGT 54 0.48 20.54 10.85 95.28
30 INT279571 Regulation of Gene_expression of CFD 2 0.21 2.86 0.31 95.20
31 INT101105 Positive_regulation of FUT1 62 0.30 55.96 9.28 94.56
32 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35 94.48
33 INT104250 Positive_regulation of Gene_expression of SPP1 17 0.69 13.22 1.44 94.48
34 INT170853 Positive_regulation of Gene_expression of CFD 7 0.23 9.89 1.41 94.32
35 INT142596 Positive_regulation of Gene_expression of Tlr2 42 0.69 38.41 6.67 94.08
36 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 93.84
37 INT112003 Localization of ROS1 94 0.73 66.32 12.16 93.12
38 INT147788 Regulation of FUT1 11 0.12 7.72 1.44 93.00
39 INT76406 Gene_expression of Hmox1 140 0.78 85.86 17.15 92.64
40 INT287003 Negative_regulation of Positive_regulation of Hmox1 2 0.34 3.1 0.63 92.56
41 INT127112 Phosphorylation of Smad2 19 0.80 11.01 5.36 92.20
42 INT218696 Negative_regulation of Phosphorylation of Smad2 3 0.42 4.36 0.92 92.20
43 INT167755 Gene_expression of Enpp2 12 0.77 57.31 5.3 92.00
44 INT166114 Gene_expression of Dmbx1 36 0.74 29.64 12.28 92.00
45 INT87823 Positive_regulation of Cxcl2 51 0.66 35.47 14.79 91.68
46 INT83955 Regulation of Cxcl2 14 0.58 9.77 4.45 91.68
47 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 90.72
48 INT182514 Binding of AGTR1 18 0.47 13.35 1.48 90.40
49 INT166119 Negative_regulation of Gene_expression of Lpar1 17 0.51 13.86 8.7 90.16
50 INT22781 Binding of COL7A1 76 0.48 41.59 6.66 89.84
51 INT16919 Gene_expression of IL36RN 48 0.48 32.78 13.83 89.52
52 INT25121 Negative_regulation of Positive_regulation of COL7A1 5 0.24 1.32 2.37 89.20
53 INT162533 Regulation of Lgals3 9 0.45 6.61 1.73 88.84
54 INT8629 Positive_regulation of COL7A1 72 0.69 40.66 12.09 88.80
55 INT88544 Gene_expression of MMRN1 102 0.75 68.8 14.55 88.48
56 INT269219 Phosphorylation of SNAI1 1 0.62 0.38 0.04 88.04
57 INT68675 Regulation of APCS 10 0.62 7.61 3.01 87.76
58 INT55741 Negative_regulation of Timp1 15 0.51 8.12 4.09 86.48
59 INT305012 Transcription of TNFAIP6 1 0.48 1.13 0.12 86.48
60 INT91320 Localization of Hmox1 8 0.81 4.06 1.28 86.48
61 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 86.44
62 INT49643 Gene_expression of Bdkrb1 39 0.78 46.49 40.21 86.40
63 INT61301 Positive_regulation of Gene_expression of Bdkrb1 7 0.68 16.95 15.44 86.40
64 INT54832 Negative_regulation of Gene_expression of Col2a1 6 0.50 2.53 3.16 86.04
65 INT66367 Gene_expression of Gsk3b 16 0.45 9.75 3.07 85.68
66 INT305021 Positive_regulation of TNFAIP6 1 0.45 1.13 0.12 85.52
67 INT54834 Gene_expression of Col2a1 48 0.72 13.5 9.41 85.48
68 INT177594 Binding of TRGV9 7 0.14 3.28 0.33 85.44
69 INT60710 Gene_expression of Col7a1 217 0.78 113.2 35.2 85.12
70 INT65265 Positive_regulation of Gene_expression of Col7a1 48 0.69 23.81 6.16 85.12
71 INT3962 Regulation of AGT 50 0.62 20.96 13.01 84.24
72 INT88223 Gene_expression of Bdkrb2 17 0.69 13.94 11.44 83.28
73 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 83.28
74 INT88221 Positive_regulation of Gene_expression of Bdkrb2 5 0.36 3.35 3.91 83.28
75 INT111603 Positive_regulation of Gene_expression of CDH1 14 0.49 11.17 1.72 83.28
76 INT16721 Negative_regulation of Cat 56 0.59 44.44 22.84 83.12
77 INT153201 Negative_regulation of Gene_expression of Col1a1 7 0.38 6.37 1.52 82.72
78 INT69215 Gene_expression of Col1a1 38 0.68 17.39 4.77 82.72
79 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 82.68
80 INT97128 Localization of SPP1 32 0.80 21.75 4.02 81.92
81 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73 81.92
82 INT252209 Positive_regulation of Gene_expression of Lgals3 10 0.57 8.29 1.62 81.52
83 INT159775 Negative_regulation of Gene_expression of Timp1 9 0.37 4.36 1.08 81.40
84 INT333390 Positive_regulation of Col4a1 1 0.04 1.19 0.17 81.36
85 INT349040 Regulation of Gene_expression of Cnn3 1 0.32 2.13 0.42 80.92
86 INT113671 Negative_regulation of Mmp3 26 0.49 6.33 7.88 80.88
87 INT77538 Gene_expression of Cnn3 2 0.55 10.24 1.55 80.52
88 INT15724 Negative_regulation of Fn1 15 0.53 5.61 3.87 80.32
89 INT55740 Gene_expression of Timp1 53 0.75 28.63 13.85 80.24
90 INT1116 Regulation of Ren 103 0.62 27.66 33.26 79.76
91 INT40249 Regulation of Regulation of Ren 4 0.36 0.83 1.05 79.76
92 INT4096 Regulation of Localization of Pth 7 0.58 3.97 0.95 78.72
93 INT333364 Negative_regulation of Positive_regulation of Pdgfa 1 0.03 0.99 0.22 78.72
94 INT241292 Transcription of TRGV9 2 0.16 1.13 0.12 78.72
95 INT96778 Positive_regulation of Pdgfa 22 0.46 12.7 5.31 78.32
96 INT329838 Negative_regulation of Tnfsf13b 4 0.19 3.81 0.2 78.24
97 INT2378 Negative_regulation of SERPINE1 47 0.59 34.55 9.9 77.92
98 INT305016 Positive_regulation of Negative_regulation of SERPINE1 1 0.10 1.13 0.11 77.92
99 INT111605 Positive_regulation of CDH1 12 0.50 7.95 1.15 77.44
100 INT4097 Localization of Pth 66 0.81 47.17 4.36 77.12
101 INT54000 Positive_regulation of SNAI1 7 0.49 5.37 0.58 75.36
102 INT133214 Regulation of PDX1 9 0.34 10.26 3.36 75.28
103 INT166115 Positive_regulation of Gene_expression of Lpar1 42 0.61 31 20.71 73.80
104 INT77536 Positive_regulation of Cnn3 2 0.43 0.58 0.11 72.84
105 INT120004 Transcription of Tp53 8 0.72 4.92 1.48 72.48
106 INT303885 Negative_regulation of Serpinh1 5 0.05 1.68 0.7 72.32
107 INT22679 Binding of SERPINE1 25 0.36 17.33 2.36 72.24
108 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94 71.76
109 INT61117 Gene_expression of Ppara 158 0.68 69.3 15.98 71.72
110 INT147517 Negative_regulation of Gene_expression of Ppara 12 0.37 3.46 2.55 71.72
111 INT24366 Positive_regulation of Localization of NPY 4 0.50 4.01 3.79 71.36
112 INT123885 Positive_regulation of Lgals3 23 0.57 24.38 6.32 71.28
113 INT302664 Positive_regulation of SMAD2 2 0.49 0.85 0.64 71.24
114 INT72060 Positive_regulation of Gene_expression of Ros1 127 0.41 76.76 20.91 70.88
115 INT11243 Localization of NPY 33 0.78 11.18 19.24 70.80
116 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 70.48
117 INT251319 Negative_regulation of Gene_expression of Fn1 4 0.07 1.82 0.74 70.36
118 INT250771 Gene_expression of Atl1 3 0.43 2.45 0.75 70.36
119 INT39758 Gene_expression of Fn1 57 0.65 34.38 6.02 69.96
120 INT860 Regulation of ALB 48 0.60 25.11 8.95 69.72
121 INT71918 Gene_expression of ACTA1 16 0.75 7.73 1.45 69.44
122 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 69.20
123 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27 69.20
124 INT56447 Positive_regulation of Icam1 64 0.64 64.14 16.16 69.20
125 INT81443 Positive_regulation of Vcam1 29 0.63 28.4 6.35 69.20
126 INT74109 Positive_regulation of Sele 26 0.48 22.32 5.84 69.20
127 INT104386 Positive_regulation of Tnpo1 4 0.49 4.82 1.17 69.20
128 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 68.48
129 INT58734 Regulation of SNAI1 3 0.60 1.26 0.2 68.24
130 INT171060 Gene_expression of PDX1 72 0.75 72.57 17.97 67.80
131 INT112425 Gene_expression of TRGV9 15 0.58 7.34 2.49 66.68
132 INT168642 Gene_expression of Cx3cr1 15 0.77 21.73 8.1 66.60
133 INT174688 Binding of Tlr2 45 0.42 36.65 5.25 66.20
134 INT157765 Negative_regulation of CDH1 32 0.53 35.72 1.15 65.84
135 INT269221 Regulation of Positive_regulation of ITK 1 0.07 0.91 0.03 65.84
136 INT103824 Positive_regulation of SOD2 26 0.70 17.42 7.17 64.96
137 INT153278 Gene_expression of Lypla1 1 0.05 1.32 0.4 64.44
138 INT189877 Gene_expression of Cdh1 55 0.58 9.36 0.66 63.76
139 INT153279 Gene_expression of Liph 1 0.58 1.3 0.4 63.40
140 INT180686 Localization of Cnn3 3 0.50 1.15 0.3 63.20
141 INT93484 Negative_regulation of Positive_regulation of Jun 30 0.58 9.31 5.18 63.12
142 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73 62.52
143 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66 62.00
144 INT185825 Localization of MMP7 10 0.78 2.85 1.11 61.92
145 INT168638 Positive_regulation of Gene_expression of Cx3cr1 6 0.65 5.15 2.19 61.24
146 INT296610 Negative_regulation of Duox2 1 0.06 2.5 0.09 60.80
147 INT126030 Regulation of CFD 4 0.21 3.92 0.83 60.48
148 INT269220 Positive_regulation of Gene_expression of ITK 4 0.14 3.07 0.41 59.76
149 INT125980 Binding of CFD 8 0.42 10.96 1.39 58.80
150 INT44145 Negative_regulation of Gene_expression of Ace 5 0.40 4.5 1.33 58.32
151 INT127459 Negative_regulation of PAH 18 0.56 15.15 1.05 58.00
152 INT389 Gene_expression of Ace 21 0.67 10.31 8.1 57.92
153 INT385 Gene_expression of Agt 182 0.78 63.62 37.91 57.60
154 INT137980 Positive_regulation of P2RX7 30 0.67 22.49 10 57.60
155 INT684 Binding of AVP 38 0.48 13.9 8.85 57.20
156 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 56.16
157 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 55.68
158 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51 55.68
159 INT15918 Gene_expression of Serpine1 60 0.62 41.73 7.72 55.48
160 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 55.24
161 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 55.24
162 INT81291 Regulation of Gene_expression of Hmox1 11 0.60 8.78 2.46 55.20
163 INT185837 Regulation of Gene_expression of MMP7 6 0.44 2.87 0.92 55.04
164 INT185836 Positive_regulation of Gene_expression of MMP7 4 0.43 0.41 0.2 55.04
165 INT12950 Gene_expression of Cat 85 0.75 35.94 15.76 54.96
166 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 54.88
167 INT102233 Gene_expression of MMP7 40 0.76 15.78 2.93 53.92
168 INT387 Regulation of Ace 18 0.45 5.24 4.24 53.88
169 INT48956 Negative_regulation of Positive_regulation of Nos2 34 0.46 13.15 11.15 53.84
170 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 53.32
171 INT72337 Positive_regulation of Positive_regulation of Nos2 37 0.65 17.02 8.11 53.32
172 INT81293 Positive_regulation of Gene_expression of Hmox1 53 0.70 41.54 7.25 53.00
173 INT168637 Negative_regulation of Cx3cr1 6 0.58 11.67 2.41 52.92
174 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26 51.00
175 INT212758 Binding of Hmgb1 40 0.44 35.6 7.41 51.00
176 INT63356 Regulation of CD44 6 0.23 6.29 0.61 50.88
177 INT102891 Positive_regulation of AGTR1 31 0.67 30.57 5.29 50.84
178 INT28594 Positive_regulation of Transcription of Agt 2 0.47 1.3 1.15 50.84
179 INT17548 Negative_regulation of Serpine1 30 0.57 24.69 3.93 50.72
180 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22 50.68
181 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54 50.56
182 INT62067 Negative_regulation of Gene_expression of Pth 13 0.41 8.24 0.61 50.56
183 INT296623 Positive_regulation of Cdh1 2 0.35 1.88 0.09 50.48
184 INT3152 Transcription of Agt 7 0.72 5.09 1.68 50.44
185 INT48233 Negative_regulation of Gene_expression of MMP1 34 0.58 12.94 9.08 50.24
186 INT330125 Transcription of AGTR1 1 0.52 1.29 0.39 50.16
187 INT6625 Negative_regulation of Pth 96 0.58 57.6 8.24 50.00
188 INT254701 Transcription of CDH1 6 0.67 2.5 0.17 49.04
189 INT269224 Regulation of Transcription of CDH1 1 0.20 0.86 0 49.04
190 INT263281 Negative_regulation of Transcription of CDH1 2 0.41 1.84 0 49.04
191 INT86370 Regulation of CDH1 10 0.54 13.89 0.7 47.92
192 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 47.68
193 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72 47.68
194 INT21582 Regulation of Gene_expression of TIMP1 20 0.61 12.39 4.77 47.68
195 INT32515 Negative_regulation of B4GALNT1 82 0.43 28.1 17.46 47.48
196 INT237303 Negative_regulation of Positive_regulation of B4GALNT1 1 0.01 0.05 0 47.48
197 INT94784 Binding of ROS1 113 0.40 71.57 10.26 47.28
198 INT74449 Positive_regulation of B4GALNT1 53 0.30 34.49 14.96 46.92
199 INT269896 Positive_regulation of Gene_expression of Smad2 9 0.40 2.15 0.69 46.88
200 INT194504 Gene_expression of Smad2 27 0.65 7.45 2.25 46.84
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