D:Interstitial Cystitis

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Disease Term
Synonyms Chronic Interstitial Cystitides, Chronic Interstitial Cystitis, CYSTITIDES CHRONIC INTERSTITIAL, Cystitides Interstitial, Cystitis Chronic Interstitial, CYSTITIS INTERSTITIAL, Hunner S Syndrome, Hunner S Ulcer, Hunner Ulcer, Hunner Ulcers, Interstitial Cystitides
Documents 1796
Hot Single Events 200
Hot Interactions 44

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Interstitial Cystitis. They are ordered first by their relevance to Interstitial Cystitis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT136989 EGF Negative_regulation of Positive_regulation of KCNJ2 1 0.04 1.09 1.1 100.00
2 INT136988 EGF Negative_regulation of KCNJ2 1 0.04 1.09 1.04 100.00
3 INT355038 NRP1 Negative_regulation of CKAP4 1 0.02 1.23 0.29 100.00
4 INT353331 Elane Positive_regulation of F2r 1 0.08 0.78 0.44 99.92
5 INT252602 Binding of Cxcl10 and Ppig 1 0.08 1.55 0.96 99.32
6 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89 97.92
7 INT56451 Ifng Positive_regulation of Tnf 1 0.00 1.92 0.59 96.88
8 INT132801 IL4 Positive_regulation of Localization of IL6 2 0.26 1.47 0.26 94.92
9 INT132818 IL4 Positive_regulation of Gene_expression of IL6 1 0.28 0.48 0.09 94.92
10 INT238005 Binding of Cxcr3 and Cxcl10 2 0.38 3.73 1.42 93.76
11 INT185937 NOS2 Regulation of Prkaca 1 0.03 1.08 0.82 93.12
12 INT94523 Binding of MT2A and ALG1 1 0.16 0.72 0.09 92.44
13 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19 91.68
14 INT113959 TNF Positive_regulation of Gene_expression of IK 1 0.02 0.66 0.69 90.00
15 INT148930 Rac1 Regulation of Chrna7 1 0.13 0.6 0.44 87.76
16 INT207113 Nfkbia Negative_regulation of Nfkb1 1 0.11 0.96 0.4 85.40
17 INT132804 Positive_regulation of IL4 Positive_regulation of CCL2 1 0.22 0.6 0.09 85.16
18 INT132794 Positive_regulation of IL13 Positive_regulation of CCL2 1 0.21 0.6 0.09 85.16
19 INT132810 Positive_regulation of IL13 Positive_regulation of IL1B 1 0.33 0.6 0.09 85.16
20 INT132815 Positive_regulation of TNF Positive_regulation of CCL2 1 0.21 0.6 0.09 85.16
21 INT132812 Positive_regulation of IL4 Positive_regulation of IL1B 1 0.34 0.6 0.09 85.16
22 INT132808 Positive_regulation of TNF Positive_regulation of IL1B 1 0.33 0.6 0.09 85.16
23 INT132793 IL4 Positive_regulation of CCL2 1 0.22 0.73 0.08 84.76
24 INT132816 IL13 Positive_regulation of CCL2 1 0.21 0.73 0.08 84.76
25 INT132811 IL1B Positive_regulation of CCL2 1 0.15 0.6 0.08 84.76
26 INT132814 TNF Positive_regulation of CCL2 1 0.21 0.6 0.08 84.76
27 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14 84.48
28 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83 84.48
29 INT132792 IL4 Positive_regulation of IL6 4 0.28 1.81 0.47 84.48
30 INT132805 IL13 Positive_regulation of IL6 1 0.27 0.73 0.08 84.48
31 INT132791 TNF Positive_regulation of KITLG 1 0.12 0.6 0.08 84.12
32 INT132803 IL13 Positive_regulation of KITLG 1 0.12 0.73 0.08 84.12
33 INT132795 IL4 Positive_regulation of KITLG 1 0.12 0.73 0.08 84.12
34 INT132800 IL1B Positive_regulation of KITLG 1 0.19 0.6 0.08 84.12
35 INT132809 TNF Positive_regulation of IL1B 2 0.33 1.26 0.16 83.84
36 INT132802 IL4 Positive_regulation of IL1B 1 0.34 0.6 0.08 83.84
37 INT132806 IL13 Positive_regulation of IL1B 1 0.33 0.6 0.08 83.84
38 INT137610 Crh Positive_regulation of Localization of Vegfa 1 0.43 0.49 0.21 83.76
39 INT137611 Crh Positive_regulation of Vegfa 1 0.43 0.49 0.21 83.44
40 INT137612 Crh Positive_regulation of Positive_regulation of Vegfa 1 0.43 0.43 0.21 83.44
41 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47 83.28
42 INT213726 Binding of Ngfr and Ntrk1 1 0.14 0.96 0.72 81.16
43 INT262563 Negative_regulation of Pax3 Regulation of Calca 1 0.01 0.75 0.76 80.56
44 INT262569 Pax3 Regulation of Calca 1 0.00 0.75 0.76 80.56
45 INT123397 F2 Positive_regulation of Gene_expression of PTAFR 1 0.05 0.51 0.32 77.64
46 INT123398 TPSAB1 Positive_regulation of Gene_expression of PTAFR 1 0.14 0.51 0.32 77.12
47 INT121541 Positive_regulation of Binding of CRH and CCL7 1 0.09 0.07 0 72.48
48 INT121542 Binding of CRH and CCL7 1 0.07 0.07 0 72.48
49 INT91832 CD81 Negative_regulation of Gene_expression of Hbegf 1 0.01 0.07 0 70.84
50 INT252599 Negative_regulation of Cxcl10 Negative_regulation of Gene_expression of Cxcr3 1 0.45 0.49 0.29 69.36
51 INT252604 Negative_regulation of Cxcl10 Negative_regulation of Gene_expression of Hand1 1 0.24 0.5 0.29 69.36
52 INT207110 Adam3 Regulation of Gene_expression of Eef1a1 1 0.01 1 0.41 69.28
53 INT252605 Ppig Positive_regulation of Gene_expression of Cx3cr1 1 0.09 1.81 0.69 68.12
54 INT252603 Ppig Positive_regulation of Gene_expression of Cx3cl1 1 0.10 1.8 0.69 67.68
55 INT95564 Positive_regulation of HRAS Positive_regulation of IL12A 1 0.03 0.7 0.45 67.52
56 INT95562 HRAS Positive_regulation of IL12A 1 0.03 0.7 0.45 67.52
57 INT95563 HRAS Positive_regulation of TNF 1 0.03 0.7 0.45 67.52
58 INT238009 Binding of Cxcr3 and Cxcl9 3 0.40 4.01 1.37 59.72
59 INT237083 Binding of Cxcl10 and Cxcl9 2 0.39 3.19 0.87 59.72
60 INT237084 Binding of Cxcl9 and Cxcl11 2 0.34 3.19 0.87 59.72
61 INT252601 Binding of Cxcl10 and Cxcl11 1 0.34 1.68 0.6 59.44
62 INT237999 Binding of Cxcr3 and Cxcl11 2 0.45 3.49 1.11 58.96
63 INT306178 Rhoa Positive_regulation of Rock2 2 0.40 1.04 0.21 56.68
64 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5 56.44
65 INT252606 IFNA1 Positive_regulation of Gene_expression of Cxcl10 1 0.02 0.56 0.18 55.24
66 INT209043 Binding of Fn1 and Slc11a1 3 0.03 1.91 0.78 53.96
67 INT226906 Binding of Ido1 and Il6 1 0.07 0.67 0.08 53.00
68 INT133449 Zfp628 Negative_regulation of Gene_expression of Mcpt1 1 0.00 0.15 0 50.00
69 INT165781 Binding of TNFSF14 and Darc 1 0.00 0 0 50.00
70 INT165772 Binding of CXCR3 and TNFSF14 1 0.36 0 0 50.00
71 INT133450 Zfp628 Negative_regulation of Mcpt1 1 0.00 0.15 0 50.00
72 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16 48.80
73 INT262582 F2rl1 Regulation of Positive_regulation of Prkca 1 0.03 0.58 0.78 40.00
74 INT262562 F2rl1 Regulation of Trpv1 1 0.12 0.58 0.77 40.00
75 INT262573 Par2 Regulation of Positive_regulation of Prkca 1 0.05 0.57 0.72 38.76
76 INT262566 Par2 Regulation of Trpv1 1 0.20 0.57 0.71 38.76
77 INT230594 Binding of Hrh1 and Hrh2 1 0.24 0.99 1.02 38.56
78 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71 38.40
79 INT262377 Binding of Comt and Fmod 1 0.06 1.47 1.29 34.16
80 INT208936 Tac1 Positive_regulation of Tacr1 1 0.13 0.39 0.25 25.60
81 INT226905 Slc11a1 Regulation of Nfkb1 1 0.04 0.41 0.03 25.00
82 INT100265 Hsp90aa1 Regulation of Positive_regulation of Esrrb 1 0.10 0.1 0 25.00
83 INT213802 Il4 Regulation of Gene_expression of Insrr 1 0.00 0.76 0.29 20.28
84 INT213808 Il12a Regulation of Gene_expression of Insrr 1 0.00 0.76 0.28 19.92
85 INT208946 Positive_regulation of Tacr1 Positive_regulation of Gene_expression of S100a8 1 0.02 1.11 0.8 9.92
86 INT226907 Binding of E2f1 and Nfkb1 1 0.14 0.6 0.12 8.12
87 INT213727 Ngf Regulation of Gene_expression of Fos 1 0.21 0.27 0.58 6.24
88 INT252600 Ppig Regulation of Hand1 1 0.06 0.43 0.17 6.20
89 INT252598 Ppig Regulation of Gene_expression of Hand1 1 0.06 0.43 0.17 6.20
90 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 5.00
91 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17 5.00
92 INT97208 Binding of Gabrg1 and Gabbr1 2 0.07 0.31 1.94 5.00
93 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92 5.00
94 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9 5.00
95 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87 5.00
96 INT121226 Ngf Regulation of Gene_expression of Trpv1 2 0.62 0.7 1.44 5.00
97 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38 5.00
98 INT181490 Tryptase Positive_regulation of F2rl1 1 0.13 1.83 1.21 5.00
99 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16 5.00
100 INT207149 Binding of F2r and Par2 1 0.17 1.64 0.92 5.00
101 INT126268 Tpsab1 Positive_regulation of F2rl1 2 0.35 1.65 0.88 5.00
102 INT262572 Ngf Positive_regulation of Mapk1 2 0.04 0.52 0.81 5.00
103 INT262564 Ngf Positive_regulation of Pik3r1 1 0.08 0.36 0.8 5.00
104 INT262579 Ngf Positive_regulation of Prkca 1 0.07 0.36 0.8 5.00
105 INT262577 Localization of Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.05 0.92 0.75 5.00
106 INT262578 Prkaca Positive_regulation of Localization of Calca 1 0.03 0.71 0.75 5.00
107 INT209040 Il3 Positive_regulation of Cxcl1 1 0.04 0.38 0.73 5.00
108 INT209061 Il3 Positive_regulation of Elf1 1 0.06 0.38 0.73 5.00
109 INT209035 Il2 Positive_regulation of Ccr1 1 0.00 0.38 0.73 5.00
110 INT209037 Il4 Positive_regulation of Csf2 1 0.03 0.38 0.73 5.00
111 INT209038 Il4 Positive_regulation of Ccr1 1 0.01 0.38 0.73 5.00
112 INT209048 Il3 Positive_regulation of Il17a 1 0.03 0.38 0.73 5.00
113 INT209058 Il4 Positive_regulation of Elf1 1 0.08 0.38 0.73 5.00
114 INT209052 Il2 Positive_regulation of Il17a 1 0.03 0.38 0.73 5.00
115 INT209034 Il4 Positive_regulation of Il17a 1 0.04 0.38 0.73 5.00
116 INT209065 Il3 Positive_regulation of Ccr1 1 0.00 0.38 0.73 5.00
117 INT209053 Il2 Positive_regulation of Elf1 1 0.06 0.38 0.73 5.00
118 INT209064 Il4 Positive_regulation of Cxcl1 1 0.05 0.38 0.73 5.00
119 INT209036 Il2 Positive_regulation of Cxcl1 1 0.04 0.38 0.73 5.00
120 INT209051 Il2 Positive_regulation of Csf2 1 0.02 0.38 0.73 5.00
121 INT209062 Il3 Positive_regulation of Csf2 1 0.02 0.38 0.73 5.00
122 INT209057 Il6 Positive_regulation of Csf2 1 0.03 0.38 0.72 5.00
123 INT209029 Il12b Positive_regulation of Elf1 1 0.24 0.37 0.72 5.00
124 INT209045 Il10 Positive_regulation of Csf2 1 0.03 0.37 0.72 5.00
125 INT209031 Il12b Positive_regulation of Ccr1 1 0.02 0.37 0.72 5.00
126 INT209030 Il12b Positive_regulation of Cxcl1 1 0.16 0.37 0.72 5.00
127 INT209039 Il6 Positive_regulation of Il17a 1 0.05 0.38 0.72 5.00
128 INT209056 Il6 Positive_regulation of Elf1 1 0.10 0.38 0.72 5.00
129 INT209028 Il12b Positive_regulation of Il17a 1 0.12 0.37 0.72 5.00
130 INT209059 Il6 Positive_regulation of Cxcl1 1 0.06 0.38 0.72 5.00
131 INT209050 Il10 Positive_regulation of Elf1 1 0.10 0.37 0.72 5.00
132 INT209041 Il10 Positive_regulation of Ccr1 1 0.01 0.37 0.72 5.00
133 INT209042 Il10 Positive_regulation of Cxcl1 1 0.07 0.37 0.72 5.00
134 INT262580 Ngf Positive_regulation of Hspg2 1 0.03 0.35 0.72 5.00
135 INT209060 Il6 Positive_regulation of Ccr1 1 0.01 0.38 0.72 5.00
136 INT209032 Il12b Positive_regulation of Csf2 1 0.08 0.37 0.72 5.00
137 INT209044 Il10 Positive_regulation of Il17a 1 0.05 0.37 0.72 5.00
138 INT262581 Prkca Positive_regulation of Phosphorylation of Trpv1 1 0.13 0.28 0.71 5.00
139 INT262571 Phosphorylation of Trpv1 Positive_regulation of Localization of Calca 1 0.17 0.71 0.7 5.00
140 INT262570 Binding of Pax3 and Trpv1 1 0.02 1.05 0.67 5.00
141 INT262576 Binding of Calca and Trpv1 1 0.13 1.05 0.66 5.00
142 INT209054 Il17a Positive_regulation of Gene_expression of Il6 1 0.10 0.45 0.65 5.00
143 INT209063 Slc11a1 Positive_regulation of Il17a 1 0.11 0.4 0.65 5.00
144 INT209055 S100a8 Positive_regulation of Gene_expression of Il6 1 0.01 0.45 0.64 5.00
145 INT207111 F2 Positive_regulation of Pawr 2 0.07 1.38 0.64 5.00
146 INT230595 Binding of TNF and Tecr 1 0.03 1 0.62 5.00
147 INT181491 Tryptase Positive_regulation of HTR1A 1 0.02 0.93 0.61 5.00
148 INT252869 Binding of Trpv1 and Phax 2 0.01 0.18 0.6 5.00
149 INT262565 Prkaca Regulation of Negative_regulation of Trpv1 1 0.05 0.21 0.5 5.00
150 INT213809 F2 Positive_regulation of F2rl3 2 0.12 0.61 0.5 5.00
151 INT209046 Slc11a1 Positive_regulation of Regulation of Tlr4 1 0.07 0.09 0.48 5.00
152 INT207141 Tlr4 Positive_regulation of Positive_regulation of Pawr 1 0.05 0.79 0.46 5.00
153 INT312813 Binding of F2rl1 and Tpsab1 1 0.01 0.26 0.46 5.00
154 INT312814 TNF Positive_regulation of Spg21 1 0.00 0.6 0.45 5.00
155 INT262575 Trpv1 Positive_regulation of Prkca 1 0.13 0.17 0.44 5.00
156 INT209049 Slc11a1 Positive_regulation of Localization of Il12a 1 0.04 0.09 0.44 5.00
157 INT353332 Binding of F2r and Pawr 1 0.18 0.67 0.39 5.00
158 INT209047 Slc11a1 Positive_regulation of Localization of Il10 1 0.10 0.52 0.36 5.00
159 INT353333 Positive_regulation of F2r Positive_regulation of Localization of Mif 1 0.46 0.26 0.32 5.00
160 INT190807 Ubd Positive_regulation of Ubd Regulation of Abp1 1 0.32 0.83 0.32 5.00
161 INT353334 F2r Positive_regulation of Mif 1 0.68 0 0.32 5.00
162 INT190806 Ubd Regulation of Abp1 1 0.20 0.82 0.32 5.00
163 INT353335 F2r Regulation of Positive_regulation of Mif 1 0.27 0.11 0.31 5.00
164 INT207143 tryptase Positive_regulation of Par2 2 0.09 0.71 0.3 5.00
165 INT207114 Binding of Plau and Plaur 1 0.19 0.7 0.29 5.00
166 INT208947 Pax3 Positive_regulation of Tacr1 Positive_regulation of Localization of Nfkb1 1 0.03 0.55 0.29 5.00
167 INT208940 Pax3 Positive_regulation of Tacr1 1 0.07 0.55 0.29 5.00
168 INT208944 Pax3 Positive_regulation of Localization of Nfkb1 1 0.03 0.55 0.29 5.00
169 INT208941 Positive_regulation of Pax3 Positive_regulation of Tacr1 1 0.05 0.55 0.29 5.00
170 INT353336 F2r Regulation of Localization of Mif 1 0.23 0.24 0.28 5.00
171 INT213816 Binding of Tcf12 and Tfeb 1 0.01 1.91 0.27 5.00
172 INT213798 Sh2b2 Regulation of tf 1 0.12 0.53 0.27 5.00
173 INT213799 Sh2b2 Regulation of Tfeb 1 0.26 0.54 0.27 5.00
174 INT353330 F2r Positive_regulation of Positive_regulation of Mif 1 0.46 0 0.26 5.00
175 INT213804 Binding of Mitf and Tfeb 1 0.24 0.81 0.24 5.00
176 INT213813 Binding of Tcf4 and Tfeb 1 0.14 0.81 0.24 5.00
177 INT209066 Slc11a1 Positive_regulation of Binding of TNF 1 0.01 1.11 0.24 5.00
178 INT226911 Slc11a1 Positive_regulation of Gene_expression of Il6 1 0.09 1.12 0.24 5.00
179 INT213805 Binding of Tcf12 and Tcf4 1 0.00 0.79 0.23 5.00
180 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22 5.00
181 INT213814 F3 Positive_regulation of Pars2 1 0.01 0.58 0.21 5.00
182 INT213812 Sh2b2 Positive_regulation of Tfeb 1 0.44 0.45 0.2 5.00
183 INT312815 IL1B Positive_regulation of Localization of Il6 1 0.00 0.33 0.2 5.00
184 INT208942 Positive_regulation of Mapk14 Positive_regulation of Positive_regulation of Jun 1 0.10 0.42 0.2 5.00
185 INT226903 Txnl1 Regulation of Ins1 1 0.01 0.59 0.19 5.00
186 INT207151 PLA2G6 Positive_regulation of Localization of F2rl1 1 0.16 0.73 0.18 5.00
187 INT207147 Pla2g1b Positive_regulation of Localization of F2rl1 1 0.03 0.73 0.18 5.00
188 INT190628 Negative_regulation of Binding of Rab7 and Sirt1 1 0.33 0.62 0.17 5.00
189 INT190637 Negative_regulation of Binding of Rab7 and Rnf115 1 0.25 0.68 0.17 5.00
190 INT207142 Spg21 Positive_regulation of Par2 1 0.02 0.48 0.17 5.00
191 INT190638 Binding of Rab7 and Sirt1 1 0.29 0.62 0.17 5.00
192 INT190630 Binding of Rab7 and Rnf115 1 0.22 0.68 0.17 5.00
193 INT190635 Binding of Lmo2 and Nr1h2 1 0.09 0.59 0.16 5.00
194 INT191337 Binding of IDO1 and GOPC 1 0.01 0.65 0.16 5.00
195 INT190629 Binding of Lmo2 and Usf1 1 0.11 0.6 0.16 5.00
196 INT191336 Binding of TSPO and GOPC 1 0.01 0.65 0.16 5.00
197 INT191338 Binding of TSPO and IDO1 1 0.02 0.65 0.16 5.00
198 INT207144 F2r Positive_regulation of Pawr 1 0.14 0.51 0.16 5.00
199 INT190634 Binding of Lmo2 and Maz 1 0.14 0.59 0.16 5.00
200 INT190633 Binding of Lmo2 and Deaf1 1 0.18 0.59 0.16 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Interstitial Cystitis. They are ordered first by their pain relevance and then by number of times they were reported in Interstitial Cystitis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT11157 Binding of EGF 88 0.48 53.73 21.25 100.00
2 INT170056 Binding of Cxcl10 11 0.45 12.72 5.32 100.00
3 INT87453 Regulation of Hbegf 3 0.20 1.05 0.94 100.00
4 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19 100.00
5 INT62510 Positive_regulation of MCS 32 0.60 11.79 5.45 100.00
6 INT87938 Regulation of P2RX3 5 0.43 2.37 2.32 99.94
7 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.92
8 INT30526 Negative_regulation of PTAFR 15 0.58 8.15 8.19 99.92
9 INT35699 Binding of Umod 3 0.41 2.3 0.46 99.92
10 INT45023 Positive_regulation of Negative_regulation of C1s 1 0.05 0.17 0.17 99.88
11 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47 99.84
12 INT104392 Gene_expression of Cxcl10 113 0.75 106.86 34.12 99.84
13 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 99.84
14 INT71717 Negative_regulation of Hbegf 15 0.39 3.63 3.18 99.84
15 INT99780 Positive_regulation of Cxcl10 43 0.69 39.67 13.27 99.84
16 INT104387 Positive_regulation of Cxcl9 24 0.67 22.26 7.87 99.84
17 INT15592 Positive_regulation of F2r 17 0.67 8.66 8.36 99.84
18 INT12034 Positive_regulation of Umod 6 0.69 3.25 1.33 99.84
19 INT11493 Positive_regulation of KLK1 21 0.67 9.22 5 99.84
20 INT104389 Positive_regulation of Gene_expression of Cxcl9 15 0.49 17.42 4.59 99.84
21 INT60423 Positive_regulation of TPSG1 11 0.57 11.02 2.55 99.84
22 INT99784 Positive_regulation of Cxcr3 22 0.66 22.44 10.36 99.84
23 INT17551 Positive_regulation of Gene_expression of HLA-DRA 31 0.70 15.39 6 99.84
24 INT220165 Positive_regulation of Cxcl11 8 0.60 9.67 2.29 99.84
25 INT134947 Negative_regulation of Gene_expression of HRH1 1 0.42 0.46 0.36 99.84
26 INT4148 Gene_expression of HRH1 11 0.77 2.71 4.22 99.84
27 INT91825 Binding of HBEGF 4 0.31 2.39 2.52 99.80
28 INT136991 Localization of HBEGF 5 0.59 3.62 1.28 99.80
29 INT136990 Gene_expression of KCNJ2 4 0.27 2.03 1.5 99.76
30 INT136994 Transcription of KCNJ2 1 0.05 1.08 1.03 99.76
31 INT91828 Negative_regulation of Gene_expression of HBEGF 1 0.47 0.45 0.52 99.76
32 INT55002 Gene_expression of ASAP1 46 0.64 22.8 3.2 99.72
33 INT20266 Positive_regulation of Bdkrb1 60 0.69 63.64 56.59 99.70
34 INT104395 Gene_expression of Cxcl9 83 0.76 73.1 19.79 99.68
35 INT237051 Gene_expression of Cxcl11 24 0.64 25.74 5.77 99.68
36 INT91830 Gene_expression of CD81 4 0.31 2.24 1.03 99.68
37 INT156054 Binding of Umod 1 0.30 0.35 0.35 99.68
38 INT56450 Negative_regulation of Gene_expression of Icam1 33 0.52 27.21 10.15 99.66
39 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 99.64
40 INT57290 Positive_regulation of IL17B 1 0.69 2.09 1.57 99.64
41 INT252585 Regulation of Cxcl11 1 0.51 0.95 0.41 99.64
42 INT73742 Negative_regulation of TECR 3 0.51 0.63 0.94 99.62
43 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 99.56
44 INT91831 Gene_expression of HBEGF 2 0.63 1.93 0.6 99.50
45 INT11941 Binding of Slc11a1 3 0.14 2.18 0.35 99.50
46 INT14600 Positive_regulation of Tpsab1 51 0.68 22.1 7.7 99.48
47 INT126760 Positive_regulation of Negative_regulation of SH2B2 1 0.05 1.01 1.6 99.48
48 INT61791 Positive_regulation of SH2B2 9 0.50 8.36 2.99 99.48
49 INT87457 Negative_regulation of CD81 3 0.37 1.73 0.42 99.44
50 INT91829 Positive_regulation of CD81 1 0.01 0.44 0.51 99.42
51 INT27739 Positive_regulation of EGF 49 0.70 28.31 13.68 99.40
52 INT136993 Positive_regulation of KCNJ2 3 0.35 3.61 2.42 99.40
53 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 99.40
54 INT71716 Binding of Hbegf 21 0.28 6.54 4.51 99.38
55 INT132326 Positive_regulation of Negative_regulation of MCS 3 0.28 1.83 0.51 99.34
56 INT170053 Binding of Cxcl9 5 0.46 6.34 2.43 99.32
57 INT16258 Gene_expression of Ntf3 121 0.78 53.93 59.03 99.32
58 INT83531 Gene_expression of KITLG 54 0.65 26 7.07 99.30
59 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 99.30
60 INT37227 Regulation of EGF 19 0.45 11.16 5.17 99.28
61 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 99.28
62 INT35612 Gene_expression of REG3A 37 0.78 33.33 10.13 99.28
63 INT87456 Regulation of CD81 1 0.17 1.71 0.43 99.28
64 INT87458 Binding of CD81 4 0.18 6.02 0.59 99.28
65 INT156053 Phosphorylation of Umod 1 0.67 0.1 0.19 99.28
66 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 99.22
67 INT168410 Gene_expression of Cxcr3 81 0.75 84.03 37.01 99.20
68 INT2036 Localization of EGF 42 0.77 21.5 9.74 99.16
69 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 99.16
70 INT49319 Regulation of Hrh2 5 0.45 2.31 5.04 99.16
71 INT9988 Regulation of Hrh1 22 0.46 12.87 22.13 99.16
72 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95 99.16
73 INT113960 Positive_regulation of Gene_expression of APOB 8 0.49 5.88 1.39 99.16
74 INT22066 Gene_expression of Phax 40 0.78 22.51 25.91 99.16
75 INT135088 Negative_regulation of Phax 15 0.36 8.93 8.29 99.16
76 INT48234 Negative_regulation of Gene_expression of PTAFR 11 0.57 3.97 6.25 99.14
77 INT62511 Negative_regulation of MCS 20 0.50 6.77 2.35 99.14
78 INT132819 Negative_regulation of Positive_regulation of MCS 2 0.35 0.61 0.1 99.14
79 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 99.08
80 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 99.04
81 INT62145 Negative_regulation of FAM20B 1 0.35 0.1 0.19 99.04
82 INT119974 Negative_regulation of P2RY2 3 0.43 1.6 1.04 99.02
83 INT136992 Phosphorylation of KCNJ2 1 0.07 1.07 1.08 98.96
84 INT11183 Negative_regulation of SH2B2 4 0.34 6.99 2.12 98.92
85 INT6882 Binding of Adrb2 5 0.47 1.97 3.55 98.92
86 INT21925 Regulation of PLB1 3 0.37 0.64 0.7 98.92
87 INT7344 Gene_expression of TAC1 132 0.75 35.48 68.26 98.88
88 INT8571 Gene_expression of B3GAT1 54 0.75 36.85 15.98 98.88
89 INT10506 Gene_expression of PTAFR 86 0.76 37.57 28.58 98.86
90 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 98.86
91 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 98.84
92 INT65907 Negative_regulation of Gene_expression of Ngf 36 0.59 19.5 20.03 98.84
93 INT89048 Gene_expression of P2RX2 28 0.75 8.75 7.9 98.82
94 INT55655 Gene_expression of DCN 17 0.75 7.98 5.98 98.82
95 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32 98.80
96 INT27955 Negative_regulation of Gene_expression of Ngf 16 0.59 10.43 10.17 98.80
97 INT59884 Gene_expression of UMOD 4 0.78 2.32 0.82 98.76
98 INT73866 Binding of Hist1h2aa 5 0.43 0.46 1.85 98.76
99 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74 98.76
100 INT51502 Positive_regulation of Elane 5 0.22 2.3 1.94 98.76
101 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52 98.72
102 INT174447 Regulation of Cxcr3 1 0.60 2.68 1.12 98.72
103 INT51244 Gene_expression of Umod 7 0.60 2.03 0.95 98.72
104 INT63041 Positive_regulation of Gene_expression of Umod 2 0.46 0.1 0.19 98.72
105 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 98.70
106 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38 98.70
107 INT59883 Positive_regulation of KLF1 1 0.02 0.59 0.39 98.70
108 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 98.70
109 INT95475 Positive_regulation of P2RX3 13 0.67 6.28 5.82 98.68
110 INT69367 Gene_expression of Fam20b 1 0.05 0.36 0.44 98.68
111 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12 98.68
112 INT92486 Positive_regulation of Gene_expression of P2RX3 5 0.49 1.56 1.82 98.68
113 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58 98.60
114 INT111599 Positive_regulation of Gene_expression of SMARCA1 1 0.49 0.6 0.6 98.60
115 INT111604 Positive_regulation of Gene_expression of PRPSAP2 1 0.12 0.6 0.6 98.60
116 INT111603 Positive_regulation of Gene_expression of CDH1 14 0.49 11.17 1.72 98.60
117 INT90800 Negative_regulation of Positive_regulation of EGF 5 0.40 2.78 1.77 98.58
118 INT13716 Positive_regulation of TH 33 0.68 19.11 16 98.52
119 INT119181 Regulation of Gene_expression of P2RX2 1 0.58 0.37 0.37 98.52
120 INT127037 Gene_expression of Ppig 26 0.65 16.08 6.84 98.48
121 INT252582 Positive_regulation of Gene_expression of Ppig 3 0.12 2.62 1.13 98.48
122 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 98.40
123 INT74064 Gene_expression of SPG21 9 0.75 4.14 2.45 98.40
124 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 98.40
125 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 98.40
126 INT111600 Gene_expression of SMARCA1 4 0.65 2.68 0.91 98.40
127 INT111608 Gene_expression of PRPSAP2 1 0.13 0.6 0.6 98.40
128 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46 98.40
129 INT104394 Positive_regulation of Gene_expression of Cxcl10 28 0.65 25.64 8.79 98.36
130 INT75688 Binding of KITLG 24 0.30 11.73 4.06 98.36
131 INT138920 Regulation of Gene_expression of Cxcl10 5 0.59 5.72 2.1 98.32
132 INT51242 Localization of Umod 3 0.80 0.96 0.38 98.32
133 INT1562 Localization of Crh 499 0.81 126.74 236.68 98.30
134 INT50740 Positive_regulation of SPG21 18 0.67 8.3 1.65 98.20
135 INT3821 Negative_regulation of C1s 13 0.42 7.89 2.08 98.20
136 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66 98.16
137 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74 98.16
138 INT87939 Gene_expression of P2RX3 23 0.75 6.15 6.62 98.16
139 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72 98.16
140 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 98.16
141 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38 98.16
142 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05 98.16
143 INT74059 Positive_regulation of Gene_expression of Nos1 55 0.70 11.5 21.39 98.16
144 INT66366 Positive_regulation of Gsk3b 15 0.68 6.56 4.27 98.16
145 INT66365 Positive_regulation of Gene_expression of Gsk3b 2 0.07 0.95 0.81 98.16
146 INT138548 Negative_regulation of Gene_expression of Adrb2 1 0.41 0.85 0.96 98.04
147 INT33480 Gene_expression of Adrb2 4 0.66 1.96 2.77 98.04
148 INT19396 Regulation of Rac1 66 0.53 37.41 30.01 98.04
149 INT94538 Gene_expression of ALG1 1 0.37 3.6 0.31 98.04
150 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 98.04
151 INT19078 Binding of Ngf 78 0.48 31.03 44.33 98.04
152 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57 98.04
153 INT199140 Binding of MT3 1 0.36 1.56 0.17 98.04
154 INT94526 Positive_regulation of Gene_expression of ALG1 1 0.33 1.9 0.15 98.04
155 INT48725 Gene_expression of IGFBP3 128 0.78 78.83 8.19 98.00
156 INT114827 Positive_regulation of Gene_expression of Tymp 13 0.45 5.69 1.11 98.00
157 INT114826 Gene_expression of Tymp 40 0.58 22.97 3.71 98.00
158 INT74376 Gene_expression of Cnr1 173 0.78 73.43 89.7 98.00
159 INT76620 Gene_expression of Cnr2 93 0.78 34.7 50.14 98.00
160 INT59464 Regulation of ISYNA1 21 0.43 12.15 4.63 97.96
161 INT67724 Regulation of Gene_expression of ISYNA1 14 0.51 5.99 3.62 97.96
162 INT121663 Gene_expression of CXCR3 76 0.77 50.96 30.62 97.96
163 INT44717 Gene_expression of TNFSF14 12 0.75 13.44 3.72 97.96
164 INT183450 Positive_regulation of GUCY2C 6 0.04 4.45 1.88 97.92
165 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 97.92
166 INT117785 Regulation of Gene_expression of EGF 7 0.44 4.22 2.87 97.88
167 INT62146 Localization of FAM20B 1 0.61 0.17 0.17 97.88
168 INT237054 Negative_regulation of Gene_expression of Cxcl10 11 0.56 10.26 3.4 97.80
169 INT49808 Localization of tryptase 11 0.78 8.74 2.67 97.80
170 INT207137 Positive_regulation of Localization of tryptase 2 0.13 1.6 0.41 97.80
171 INT207130 Negative_regulation of Localization of tryptase 1 0.12 0.75 0.38 97.80
172 INT87452 Negative_regulation of Binding of Hbegf 4 0.32 1.94 1.11 97.60
173 INT2037 Negative_regulation of EGF 30 0.59 15.05 6.81 97.60
174 INT4806 Localization of TPSAB1 29 0.80 5.05 10.52 97.60
175 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 97.56
176 INT66367 Gene_expression of Gsk3b 16 0.45 9.75 3.07 97.56
177 INT73594 Positive_regulation of Gene_expression of ISYNA1 61 0.55 31.35 13.45 97.52
178 INT137609 Localization of Vegfa 22 0.78 14.67 3.01 97.48
179 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89 97.48
180 INT73837 Positive_regulation of Gene_expression of TAC1 6 0.67 3.49 2.68 97.48
181 INT31758 Positive_regulation of Egf 32 0.66 19.42 3.64 97.44
182 INT62895 Gene_expression of NOSTRIN 51 0.75 28.8 10.68 97.44
183 INT111594 Positive_regulation of Gene_expression of NOSTRIN 20 0.32 8.69 5 97.44
184 INT73960 Regulation of Gene_expression of NOSTRIN 3 0.54 1.41 0.97 97.44
185 INT71718 Positive_regulation of Hbegf 4 0.59 0.63 0.16 97.44
186 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02 97.44
187 INT49130 Positive_regulation of IGFBP3 49 0.63 27.55 4.78 97.44
188 INT74216 Binding of Icam1 16 0.48 10.11 2.69 97.32
189 INT252595 Regulation of Negative_regulation of Ppig 1 0.12 0.78 0.34 97.32
190 INT252589 Regulation of Negative_regulation of Cxcl10 1 0.43 0.77 0.34 97.32
191 INT19450 Binding of TNFSF14 7 0.37 0.87 0.86 97.32
192 INT1361 Negative_regulation of Gnrhr 118 0.58 57.77 35.54 97.30
193 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 97.24
194 INT87459 Negative_regulation of Fam20b 1 0.31 0.33 0.38 97.20
195 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 97.16
196 INT199138 Gene_expression of MT3 1 0.78 4.07 0.3 97.16
197 INT95565 Positive_regulation of IL12A 47 0.56 33.96 10.16 97.16
198 INT69203 Positive_regulation of Ntf3 43 0.66 19.16 16.49 97.12
199 INT82226 Negative_regulation of Gene_expression of EGF 11 0.58 6.36 2.13 97.08
200 INT28738 Positive_regulation of PLB1 7 0.40 3.36 2.35 97.08
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