D:Intervertebral Disk Degeneration

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Disease Term
Synonyms DEGENERATION DISC, Degeneration Intervertebral Disk, Degenerations Disc, Degenerations Intervertebral Disk, Degenerative Intervertebral Disks, Degradation Disc, Degradations Disc, Disc Degeneration, Disc Degenerations, DISC DEGRADATION, Disc Degradations
Documents 509
Hot Single Events 200
Hot Interactions 11

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Intervertebral Disk Degeneration. They are ordered first by their relevance to Intervertebral Disk Degeneration and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT245727 Binding of SUGT1 and DISC1 1 0.00 1.57 0 100.00
2 INT245730 RENBP Regulation of DISC1 1 0.01 0.58 0 100.00
3 INT245732 Binding of COL9A2 and DISC1 1 0.07 1.34 0.08 100.00
4 INT245733 Binding of VDR and DISC1 1 0.03 0.75 0 100.00
5 INT245728 Binding of TRNAP2 and DISC1 1 0.03 0.54 0 100.00
6 INT245731 Binding of COL5A2 and DISC1 1 0.01 0.42 0 94.40
7 INT245729 Binding of COL9A1 and COL9A3 1 0.29 0.52 0 91.00
8 INT245734 Binding of COL9A1 and COL9A2 1 0.26 0.52 0 91.00
9 INT250913 Col7a1 Regulation of Thbs2 Regulation of Col7a1 1 0.00 0.35 0.13 82.76
10 INT250912 Thbs2 Regulation of Thbs2 Regulation of Col7a1 1 0.03 0.35 0.13 82.76
11 INT250907 Thbs2 Regulation of Col7a1 1 0.03 0.35 0.13 82.76
12 INT245726 SOX9 Regulation of SGCG 1 0.00 0.29 0 77.32
13 INT245735 SOX9 Regulation of COL5A2 1 0.07 0.29 0 77.32
14 INT250911 Thbs2 Regulation of Mmp2 1 0.05 0.3 0.13 72.12
15 INT250910 Thbs2 Regulation of Tgm2 1 0.04 0.3 0.13 72.12
16 INT160541 Binding of BDNF and PSIP1 4 0.49 1.94 1.02 71.36
17 INT159655 Binding of BDNF and INSRR 2 0.00 1.25 1.26 71.20
18 INT287234 PDLIM7 Positive_regulation of Gene_expression of BMP7 1 0.14 0.12 0.03 68.80
19 INT287233 PDLIM7 Positive_regulation of Gene_expression of BMP2 1 0.07 0.12 0.03 68.80
20 INT138133 Nfkb1 Regulation of Positive_regulation of Mmp13 1 0.00 0.31 0.07 65.04
21 INT231605 Binding of PSMD1 and SGCG 1 0.02 0.34 0.04 62.56
22 INT250934 Binding of BDNF and NGF 3 0.39 0.62 1.34 62.08
23 INT322891 Sox9 Regulation of Transcription of Col2a1 1 0.10 0.12 0.04 60.12
24 INT138134 Nfkb1 Positive_regulation of Adamts4 1 0.01 0.26 0.06 54.72
25 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3 53.44
26 INT311927 AASDH Positive_regulation of NRP2 1 0.02 0.1 0.03 46.72
27 INT350169 Binding of DMD and MRI1 1 0.11 3.08 0.54 46.56
28 INT162241 Binding of COL7A1 and MMP13 2 0.03 0.86 0.73 44.12
29 INT250932 IL1B Regulation of Gene_expression of BDNF 1 0.06 0.24 0.69 27.96
30 INT171990 Binding of DMD and VDR 5 0.05 2.58 0.39 17.72
31 INT136273 NGF Regulation of Gene_expression of BDNF 2 0.41 1.14 1.78 5.00
32 INT159657 Binding of INSRR and NGF 3 0.00 1.65 1.48 5.00
33 INT160540 Binding of NGF and PSIP1 2 0.29 1.43 1.12 5.00
34 INT265566 Binding of PDE4D and PTPN5 1 0.03 0.81 0.85 5.00
35 INT318981 Binding of CALR and GOPC 1 0.03 0.77 0.64 5.00
36 INT220155 IL1RN Regulation of IL1B 2 0.50 0.93 0.61 5.00
37 INT250933 IL1B Positive_regulation of Gene_expression of BDNF 1 0.10 0.27 0.5 5.00
38 INT307675 Binding of IL1R1 and SNRNP70 1 0.02 1.05 0.45 5.00
39 INT297972 MAPK14 Negative_regulation of ING5 1 0.21 1.67 0.33 5.00
40 INT318980 Binding of CALR and Positive_regulation of Localization of GOPC 1 0.04 0.32 0.24 5.00
41 INT297965 MAPK14 Negative_regulation of GADD45A 1 0.05 1 0.21 5.00
42 INT250908 Binding of Mmp2 and Tsp1 1 0.04 0.09 0.15 5.00
43 INT250906 Binding of Mmp2 and Thbs2 1 0.06 0.09 0.15 5.00
44 INT297967 MAPK14 Negative_regulation of SCUBE3 1 0.01 0.67 0.12 5.00
45 INT269788 Binding of FN1 and TGFB1 1 0.00 0.29 0.1 5.00
46 INT288219 Cigs1 Regulation of Nrgn 1 0.00 0.87 0.1 5.00
47 INT297968 Positive_regulation of Binding of BMP2 and IL17C 1 0.21 0.26 0.08 5.00
48 INT297970 Binding of BMP2 and IL17C 1 0.15 0.26 0.08 5.00
49 INT297964 Binding of CDK8 and MAP3K11 1 0.26 0.29 0.07 5.00
50 INT297969 Positive_regulation of Binding of CDK8 and MAP3K11 1 0.35 0.29 0.07 5.00
51 INT297971 Positive_regulation of Binding of CDK8 and MAPK1 1 0.22 0.3 0.07 5.00
52 INT297963 Binding of CDK8 and MAPK1 1 0.16 0.29 0.07 5.00
53 INT311925 Binding of NRP2 and SEMA3A 1 0.26 0.06 0.04 5.00
54 INT173056 Binding of NRP2 and NRP1 2 0.24 0.61 0.04 5.00
55 INT311926 Binding of NRP1 and SEMA3A 1 0.26 0.48 0.04 5.00
56 INT298000 MAP3K4 Positive_regulation of Gene_expression of Gadd45b 1 0.27 0.72 0.03 5.00
57 INT184208 IL1B Negative_regulation of SOX9 1 0.32 0 0.03 5.00
58 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03 5.00
59 INT298002 Gene_expression of Gadd45b Positive_regulation of MAPK14 1 0.29 0.67 0.03 5.00
60 INT298001 Gene_expression of Gadd45b Positive_regulation of MAP3K4 1 0.25 0.72 0.03 5.00
61 INT184209 IL1B Negative_regulation of Gene_expression of SOX6 1 0.46 0.05 0.03 5.00
62 INT297962 MAP3K4 Positive_regulation of MAPK14 1 0.21 0.66 0.03 5.00
63 INT320029 Gene_expression of SOX9 Positive_regulation of Gene_expression of COL7A1 1 0.03 0 0 5.00
64 INT184210 IL1B Negative_regulation of Gene_expression of COL1A2 1 0.04 0 0 5.00
65 INT171991 Binding of DMD and ERAL1 1 0.01 0.54 0 5.00
66 INT311948 Binding of NRP1 and Plxna3 1 0.05 0.26 0 5.00
67 INT311947 Binding of SEMA3A and Plxna3 1 0.07 0.26 0 5.00
68 INT320028 Gene_expression of GDF6 Positive_regulation of Gene_expression of COL7A1 1 0.01 0 0 5.00
69 INT350168 Binding of DMD and PROC 1 0.00 0.67 0 5.00
70 INT297966 CDKN1A Positive_regulation of TP53 1 0.08 0.49 0 5.00
71 INT184211 GOPC Negative_regulation of Gene_expression of ADAMTS5 1 0.07 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Intervertebral Disk Degeneration. They are ordered first by their pain relevance and then by number of times they were reported in Intervertebral Disk Degeneration. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT245748 Binding of DISC1 1 0.07 5.21 1.08 100.00
2 INT245744 Protein_catabolism of DISC1 1 0.18 4.92 0.21 100.00
3 INT245736 Gene_expression of DISC1 13 0.61 7.65 1.33 100.00
4 INT245737 Positive_regulation of Protein_catabolism of DISC1 1 0.09 1.04 0.06 100.00
5 INT245760 Regulation of Gene_expression of DISC1 1 0.08 0.72 0.07 100.00
6 INT245743 Positive_regulation of Gene_expression of DISC1 1 0.09 0.72 0.07 100.00
7 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 100.00
8 INT245764 Regulation of DISC1 1 0.08 1.23 0.38 100.00
9 INT245742 Positive_regulation of DISC1 1 0.13 0.83 0.04 100.00
10 INT245752 Positive_regulation of Binding of SOX9 1 0.41 0.48 0 100.00
11 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 99.96
12 INT122051 Negative_regulation of ROM1 17 0.48 9.11 3.38 99.96
13 INT118196 Gene_expression of ROM1 18 0.66 4.81 1.19 99.96
14 INT174541 Positive_regulation of Gene_expression of COL5A2 18 0.36 14.17 2.12 99.96
15 INT245747 Positive_regulation of Binding of COL9A3 1 0.42 1.05 0.06 99.90
16 INT36338 Gene_expression of NRP2 29 0.67 6.47 2.4 99.90
17 INT311944 Negative_regulation of Gene_expression of NRP2 1 0.39 0.17 0 99.90
18 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 99.84
19 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 99.84
20 INT62421 Gene_expression of Trpc2 8 0.68 5.48 0.67 99.84
21 INT245751 Gene_expression of COL9A2 4 0.65 1.83 0.04 99.80
22 INT184215 Negative_regulation of Gene_expression of ADAMTS4 2 0.27 0.23 0.12 99.80
23 INT84924 Positive_regulation of Gene_expression of NGF 29 0.68 17.91 16.46 99.76
24 INT103469 Positive_regulation of Gene_expression of BDNF 59 0.67 24.39 18.36 99.76
25 INT180971 Protein_catabolism of GOPC 21 0.77 6.15 2.98 99.76
26 INT192587 Negative_regulation of Protein_catabolism of GOPC 4 0.22 1.15 0.41 99.76
27 INT102639 Positive_regulation of VDR 31 0.69 18.05 2.38 99.72
28 INT8392 Regulation of Gene_expression of Qrfp 37 0.54 6.9 19.02 99.68
29 INT245740 Binding of COL9A3 2 0.31 1.85 0.08 99.62
30 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 99.56
31 INT11106 Gene_expression of Lbp 10 0.67 10.29 4.52 99.52
32 INT159214 Positive_regulation of Gene_expression of BMP7 6 0.46 2.16 0.51 99.52
33 INT170601 Positive_regulation of Gene_expression of GOPC 122 0.43 42.79 11.68 99.52
34 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 99.48
35 INT70265 Regulation of MRI1 42 0.39 30.95 14.18 99.44
36 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12 99.36
37 INT129777 Regulation of Col9a3 1 0.22 0.46 0.03 99.32
38 INT287241 Positive_regulation of BMP7 10 0.43 2.68 1.38 99.28
39 INT1028 Positive_regulation of Lbp 102 0.69 67.86 46.05 99.24
40 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 99.20
41 INT184223 Positive_regulation of Gene_expression of ADAMTS4 6 0.43 1.07 0.98 99.18
42 INT245765 Binding of SOX9 1 0.31 0.87 0 99.16
43 INT73234 Positive_regulation of Lbp 13 0.69 12.55 8.57 99.06
44 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 99.04
45 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45 99.00
46 INT203646 Gene_expression of STIP1 26 0.63 23.57 1.14 99.00
47 INT173591 Gene_expression of ADAMTS4 7 0.48 3.65 4.8 98.98
48 INT166715 Gene_expression of Sox9 16 0.65 6.39 0.92 98.96
49 INT211945 Negative_regulation of Gene_expression of Sox9 3 0.44 0.63 0 98.96
50 INT12081 Localization of TGFB1 64 0.81 35.4 17.47 98.96
51 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4 98.96
52 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09 98.96
53 INT50135 Positive_regulation of Dcn 5 0.45 0.7 0.44 98.94
54 INT141148 Gene_expression of BMP7 24 0.71 14.34 3.44 98.88
55 INT155039 Gene_expression of ADAMTS5 23 0.67 7.85 3.22 98.84
56 INT211361 Regulation of RENBP 5 0.08 2.8 0.38 98.84
57 INT173592 Binding of COL5A2 32 0.33 9.14 2.48 98.80
58 INT3364 Binding of SGCG 87 0.47 31.93 17.24 98.72
59 INT64777 Negative_regulation of COL5A2 32 0.38 17.4 2.28 98.72
60 INT173876 Positive_regulation of Positive_regulation of COL7A1 3 0.25 1.57 0.24 98.60
61 INT245741 Negative_regulation of Gene_expression of DISC1 2 0.17 1.29 0.34 98.52
62 INT108629 Negative_regulation of Regulation of MMP2 1 0.41 0.7 0.52 98.48
63 INT8629 Positive_regulation of COL7A1 72 0.69 40.66 12.09 98.40
64 INT245754 Regulation of Positive_regulation of COL9A2 1 0.34 0.74 0.06 98.40
65 INT245738 Positive_regulation of COL9A2 1 0.38 0.72 0.06 98.40
66 INT9088 Negative_regulation of LBP 48 0.58 33.06 25.89 98.36
67 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98 98.32
68 INT129962 Positive_regulation of Gene_expression of MMP13 41 0.65 20.74 8.54 98.32
69 INT8346 Gene_expression of Qrfp 136 0.70 19.49 70.21 98.30
70 INT145306 Gene_expression of Sox9 5 0.54 2.47 0.8 98.20
71 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 98.08
72 INT108628 Regulation of MMP2 27 0.60 14.85 6.06 97.96
73 INT106468 Regulation of Gene_expression of MMP2 11 0.50 3.53 2.77 97.96
74 INT37618 Gene_expression of Col2a1 50 0.70 33.88 11.58 97.84
75 INT145312 Localization of CHI3L1 8 0.78 12.71 1.26 97.72
76 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 97.68
77 INT173877 Positive_regulation of Gene_expression of INCENP 14 0.08 7.83 1.28 97.60
78 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31 97.60
79 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 97.40
80 INT153666 Gene_expression of CAV1 156 0.77 120.99 3.9 97.40
81 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 97.36
82 INT156148 Gene_expression of CTGF 16 0.78 9.98 2.87 96.84
83 INT19763 Gene_expression of CTs 69 0.78 32.92 18.87 96.84
84 INT245756 Regulation of Binding of DISC1 1 0.08 0.63 0.16 96.56
85 INT161549 Negative_regulation of TDRD6 2 0.17 1.08 0.58 96.24
86 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 96.12
87 INT16478 Positive_regulation of Plg 29 0.45 18.07 4.07 95.88
88 INT10049 Negative_regulation of SERPINA1 56 0.59 44.52 9.93 95.82
89 INT209948 Gene_expression of CLEC3B 3 0.78 11.51 0.6 95.76
90 INT245750 Regulation of COL9A3 1 0.20 0.7 0.06 95.72
91 INT27933 Gene_expression of NCOR2 65 0.72 31.35 24.23 95.56
92 INT128920 Gene_expression of Runx2 4 0.74 2.6 0.92 95.32
93 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38 95.08
94 INT220088 Positive_regulation of Positive_regulation of CDKN2A 4 0.49 4.04 0.44 95.08
95 INT84825 Gene_expression of CD36 121 0.78 43.73 33.23 95.04
96 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15 94.92
97 INT21582 Regulation of Gene_expression of TIMP1 20 0.61 12.39 4.77 94.88
98 INT245759 Localization of DISC1 1 0.14 2.85 0.04 94.80
99 INT245757 Localization of SOX9 4 0.62 0.8 0 94.60
100 INT63374 Regulation of Gene_expression of NGF 12 0.45 5.6 6.4 94.40
101 INT103474 Regulation of Gene_expression of BDNF 40 0.60 12.14 9.65 94.40
102 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71 94.36
103 INT134968 Localization of Ecm1 20 0.32 27.27 4.31 94.32
104 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 94.28
105 INT129776 Binding of Col9a3 1 0.18 0.68 0.13 93.88
106 INT129774 Binding of Trpc2 2 0.18 0.73 0.12 93.88
107 INT97908 Binding of Col9a2 3 0.18 2.51 0.29 93.88
108 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 93.84
109 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 93.84
110 INT196176 Gene_expression of SEMA3A 3 0.75 4.75 2.17 93.76
111 INT280234 Localization of Ctgf 3 0.51 2.35 0.09 93.52
112 INT352011 Positive_regulation of Localization of Ctgf 1 0.23 0.17 0 93.52
113 INT1221 Regulation of SGCG 65 0.60 24.21 22.94 93.44
114 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54 93.24
115 INT174027 Negative_regulation of Protein_catabolism of BSG 1 0.01 0.52 0.23 93.04
116 INT110738 Positive_regulation of Negative_regulation of TIMP1 4 0.44 0.44 0.45 92.92
117 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 92.88
118 INT171998 Binding of DMD 58 0.47 38.13 3.35 92.60
119 INT245762 Transcription of COL5A2 4 0.09 2.82 0 92.56
120 INT245761 Positive_regulation of Regulation of COL5A2 1 0.06 0.76 0 92.56
121 INT101177 Regulation of COL5A2 12 0.45 4.03 0.62 92.56
122 INT174029 Protein_catabolism of BSG 5 0.01 2.5 0.95 92.56
123 INT48314 Gene_expression of NTRK2 17 0.75 7.84 7.83 92.48
124 INT181922 Binding of RENBP 16 0.36 13.92 3.71 91.84
125 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56 91.64
126 INT32624 Regulation of LBP 15 0.60 11.48 8.71 91.44
127 INT73297 Positive_regulation of Transcription of Col1a1 2 0.32 3.12 0.14 91.36
128 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 91.16
129 INT245739 Gene_expression of COL9A1 1 0.54 0.53 0 90.88
130 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 90.88
131 INT204547 Positive_regulation of Gene_expression of Col1a2 2 0.04 2.08 0.91 90.76
132 INT8890 Transcription of Col1a1 10 0.63 4.02 2.48 90.64
133 INT67719 Positive_regulation of Col1a1 21 0.44 8.87 3.12 90.64
134 INT141151 Regulation of PSMD1 16 0.40 8.19 5.86 90.52
135 INT53290 Gene_expression of OPN1LW 5 0.31 6.9 9.15 90.44
136 INT141149 Localization of OPN1LW 1 0.01 0.38 0.07 90.44
137 INT156137 Gene_expression of Col1a2 28 0.73 13.3 3.99 90.40
138 INT169875 Negative_regulation of Ercc1 3 0.43 3.07 0.17 90.32
139 INT169876 Negative_regulation of Ercc4 1 0.42 1.34 0.08 90.32
140 INT179644 Gene_expression of RENBP 26 0.35 13.74 1.38 90.32
141 INT211363 Positive_regulation of RENBP 13 0.22 13.26 6.48 90.32
142 INT11893 Positive_regulation of Ptger2 96 0.69 31.49 21.92 90.24
143 INT62292 Positive_regulation of PTGES2 2 0.02 0.51 0.27 90.24
144 INT67890 Positive_regulation of Gene_expression of SGCG 26 0.67 9.91 6.41 90.00
145 INT245755 Gene_expression of COL9A3 1 0.57 0.54 0 89.92
146 INT20552 Negative_regulation of Gene_expression of COL2A1 29 0.56 11.92 4.81 89.76
147 INT11658 Regulation of Gene_expression of COL2A1 9 0.62 3.09 1.11 89.76
148 INT114490 Gene_expression of PDLIM7 17 0.78 11.35 1.42 89.40
149 INT287235 Positive_regulation of Gene_expression of PDLIM7 1 0.13 0.18 0.08 89.40
150 INT245725 Positive_regulation of Negative_regulation of Col1a1 1 0.21 0.7 0 89.32
151 INT120860 Positive_regulation of Gene_expression of Col1a1 12 0.44 4.84 1.34 89.32
152 INT148721 Binding of PSMD1 13 0.31 4.78 1.76 89.28
153 INT141150 Localization of BMP7 4 0.56 2.84 0.76 89.28
154 INT102680 Protein_catabolism of COL7A1 49 0.69 34.68 15.78 89.28
155 INT121496 Gene_expression of TERT 107 0.78 45.6 7.42 89.04
156 INT245753 Regulation of Transcription of COL5A2 1 0.08 0.64 0 89.04
157 INT153201 Negative_regulation of Gene_expression of Col1a1 7 0.38 6.37 1.52 88.96
158 INT59473 Negative_regulation of Col1a1 4 0.25 1.33 1.24 88.96
159 INT69215 Gene_expression of Col1a1 38 0.68 17.39 4.77 88.96
160 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 88.80
161 INT6474 Positive_regulation of Gene_expression of IL1RN 34 0.69 21.87 10.99 88.80
162 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 88.72
163 INT6849 Localization of IL1B 229 0.81 112.56 69.63 88.56
164 INT25123 Negative_regulation of COL7A1 42 0.58 19.98 5.96 88.24
165 INT129775 Gene_expression of Col9a2 1 0.11 0.76 0.12 88.20
166 INT129778 Gene_expression of Col9a3 1 0.33 0.76 0.12 88.20
167 INT49027 Gene_expression of TYRP1 35 0.75 9.81 6.06 88.00
168 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 87.48
169 INT322883 Regulation of Transcription of Sox9 1 0.43 0.18 0 87.28
170 INT322886 Transcription of Sox9 1 0.50 0.25 0 87.28
171 INT287238 Binding of GDF5 1 0.16 0.42 0.04 86.68
172 INT322889 Regulation of Transcription of Runx2 1 0.32 0.43 0 86.56
173 INT322885 Transcription of Runx2 1 0.50 1.08 0 86.56
174 INT344944 Positive_regulation of TDRD6 1 0.20 0.64 0.14 86.44
175 INT196771 Localization of Nrgn 3 0.44 0.86 0.95 86.00
176 INT245745 Regulation of TRNAP2 1 0.16 0.45 0 85.76
177 INT68591 Regulation of TYRP1 14 0.44 3.93 5.05 85.72
178 INT134663 Gene_expression of SOX9 40 0.75 9.07 1.2 85.68
179 INT297991 Gene_expression of GAS1 1 0.19 0.82 0.03 85.44
180 INT5333 Gene_expression of NPEPPS 45 0.65 26.34 15.25 84.96
181 INT154867 Gene_expression of CECR 28 0.57 6.97 3.72 84.80
182 INT312566 Positive_regulation of Gene_expression of CECR 1 0.19 1.67 0.38 84.80
183 INT257455 Binding of PDLIM5 2 0.08 1.72 0.64 84.60
184 INT2093 Gene_expression of GAST 50 0.78 32.32 7.98 84.48
185 INT147584 Localization of AIS 38 0.63 12.83 5.27 84.24
186 INT57274 Positive_regulation of Gene_expression of COL7A1 50 0.69 24.19 4.72 84.16
187 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82 84.00
188 INT287236 Positive_regulation of Positive_regulation of BMP2 1 0.29 0.08 0.04 83.88
189 INT35269 Localization of SGCG 38 0.78 14.68 9.01 83.56
190 INT28903 Gene_expression of IDE 3 0.64 1.8 1 83.44
191 INT113671 Negative_regulation of Mmp3 26 0.49 6.33 7.88 83.40
192 INT138128 Protein_catabolism of Adamts4 1 0.10 0.36 0.09 83.40
193 INT130014 Positive_regulation of BMP2 11 0.66 5.34 1.42 83.28
194 INT238049 Positive_regulation of Gene_expression of BMP2 8 0.51 2.06 0.59 83.28
195 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 82.88
196 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 82.88
197 INT245749 Gene_expression of TRNAP2 1 0.27 1.16 0 82.80
198 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05 82.80
199 INT84911 Gene_expression of SUGT1 43 0.11 19.85 4.54 82.80
200 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 82.16
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