D:Intestinal Pseudo-obstruction

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Disease Term
Synonyms IDIOPATHIC INTESTINAL PSEUDO OBSTRUCTION, Idiopathic Intestinal Pseudo Obstructions, Ileus Paralytic, INTESTINAL PSEUDO OBSTRUCTION, INTESTINAL PSEUDO OBSTRUCTION IDIOPATHIC, Intestinal Pseudo Obstructions, Intestinal Pseudo Obstructions Idiopathic, Intestinal Pseudoobstruction, Intestinal Pseudoobstructions, Myopathies Visceral, Myopathy Visceral
Documents 200
Hot Single Events 11
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Intestinal Pseudo-obstruction. They are ordered first by their relevance to Intestinal Pseudo-obstruction and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT115261 Gene_expression of Nos2 Positive_regulation of Positive_regulation of Npr1 1 0.05 0.67 0.31 75.00
2 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 5.00
3 INT353010 Binding of GJA8 and TNF 1 0.02 0.24 0.33 5.00
4 INT353009 Binding of GJA8 and VSIG1 1 0.00 0 0.29 5.00
5 INT353011 GJA8 Regulation of USE1 1 0.00 0.35 0.13 5.00
6 INT76972 Prl Regulation of Il6 1 0.01 0.06 0 5.00
7 INT76971 Prl Regulation of Gene_expression of Il6 1 0.01 0.06 0 5.00
8 INT273197 Binding of BCR and COPD 1 0.03 0.4 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Intestinal Pseudo-obstruction. They are ordered first by their pain relevance and then by number of times they were reported in Intestinal Pseudo-obstruction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT1261 Localization of Adh1 63 0.81 19.36 16.09 98.50
2 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 96.84
3 INT241581 Regulation of Htr4 6 0.44 1.34 2.19 86.60
4 INT84541 Binding of Tapbp 3 0.31 2.21 0.29 86.36
5 INT80862 Negative_regulation of CYP3A5 5 0.57 1.66 2.13 85.04
6 INT121682 Gene_expression of CYP3A5 3 0.73 5.09 0.65 83.20
7 INT162968 Negative_regulation of Gene_expression of CYP3A5 2 0.40 1.65 0.43 83.20
8 INT82839 Negative_regulation of ABCB1 61 0.59 16.09 8.83 82.36
9 INT138555 Negative_regulation of Tymp 3 0.39 3.31 0.74 81.04
10 INT6625 Negative_regulation of Pth 96 0.58 57.6 8.24 80.88
11 INT8388 Positive_regulation of Vip 142 0.70 39.72 67.61 80.84
12 INT9012 Localization of Vip 283 0.81 31.71 106.16 79.32
13 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 77.60
14 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 77.60
15 INT11077 Positive_regulation of Htr3a 63 0.67 15.61 22.7 77.04
16 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 75.60
17 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 75.00
18 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 75.00
19 INT26487 Positive_regulation of Npr1 17 0.70 10.01 8.78 75.00
20 INT89756 Positive_regulation of Positive_regulation of Npr1 2 0.47 0.9 1.19 75.00
21 INT19211 Binding of Shbg 35 0.48 16.29 3.31 74.48
22 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 69.08
23 INT135319 Positive_regulation of Positive_regulation of CRP 20 0.50 26.45 5.61 69.08
24 INT294082 Positive_regulation of CORO7 5 0.39 3.14 0.22 67.32
25 INT204122 Gene_expression of GJA8 13 0.47 22.98 3.04 61.92
26 INT251830 Binding of TYMP 2 0.13 4.36 0.37 60.56
27 INT287 Localization of Cck 518 0.81 86.84 364.04 60.32
28 INT2862 Positive_regulation of Localization of Cck 108 0.70 20.75 94.25 60.32
29 INT219022 Positive_regulation of IgM 1:10240 1 0.01 1.44 0.16 55.00
30 INT220336 Negative_regulation of HMGB1 3 0.43 0.97 0.21 49.64
31 INT106263 Gene_expression of R3hcc1 4 0.44 9.36 0.88 49.60
32 INT9069 Regulation of Htr3a 29 0.60 6.18 16.55 42.00
33 INT19759 Gene_expression of LBP 77 0.77 56.44 33.23 40.24
34 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 39.92
35 INT343806 Gene_expression of CORO7 3 0.57 2.54 1.18 39.12
36 INT1027 Gene_expression of Lbp 132 0.77 106.7 54.16 38.72
37 INT183910 Negative_regulation of Gene_expression of Lbp 10 0.35 9.78 6.15 38.72
38 INT9372 Negative_regulation of Lbp 86 0.58 46.54 41.71 38.32
39 INT195755 Negative_regulation of Negative_regulation of Lbp 1 0.11 0.98 0.09 38.32
40 INT158064 Negative_regulation of Gene_expression of LBP 1 0.41 1.54 0.97 35.08
41 INT344582 Gene_expression of OCR1 1 0.06 1.3 0.12 34.92
42 INT9088 Negative_regulation of LBP 48 0.58 33.06 25.89 34.68
43 INT220337 Negative_regulation of Negative_regulation of LBP 1 0.35 0.35 0.08 34.68
44 INT260444 Binding of War 2 0.19 1.33 0 34.24
45 INT9832 Gene_expression of Shbg 96 0.75 56.71 12.19 31.52
46 INT74254 Binding of PTPRC 16 0.36 8.37 1.27 29.60
47 INT1028 Positive_regulation of Lbp 102 0.69 67.86 46.05 28.12
48 INT184269 Gene_expression of HMGB1 51 0.77 42.96 4.55 23.16
49 INT220335 Gene_expression of UROD 34 0.54 24.53 2.89 23.16
50 INT10019 Binding of CD8A 57 0.36 31.49 10.08 18.56
51 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 18.48
52 INT135720 Gene_expression of War 7 0.34 3.99 0.28 18.36
53 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 10.92
54 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
55 INT7114 Positive_regulation of Ltp 1192 0.62 290.76 755.77 5.00
56 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
57 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 5.00
58 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
59 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
60 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 5.00
61 INT626 Localization of CALCA 289 0.81 125.39 221.15 5.00
62 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
63 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
64 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 5.00
65 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 5.00
66 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
67 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 5.00
68 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
69 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 5.00
70 INT5008 Localization of Calca 204 0.81 80.35 125.16 5.00
71 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
72 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75 5.00
73 INT1530 Regulation of Gh 382 0.61 115.96 112.47 5.00
74 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84 5.00
75 INT12476 Negative_regulation of TRPV1 124 0.59 47.95 77.98 5.00
76 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 5.00
77 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42 5.00
78 INT14049 Positive_regulation of GRIN1 102 0.70 48.31 71.06 5.00
79 INT9664 Binding of LBP 127 0.48 94.9 63.42 5.00
80 INT46 Localization of Ren 233 0.81 46.15 62.44 5.00
81 INT10706 Regulation of Il6 150 0.62 93.23 62.34 5.00
82 INT12175 Positive_regulation of PDYN 86 0.69 18.27 62.04 5.00
83 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79 5.00
84 INT4985 Positive_regulation of Tac1 81 0.69 35.79 50.67 5.00
85 INT8713 Regulation of Tac1 56 0.60 25.29 45.94 5.00
86 INT27798 Gene_expression of Ntrk2 111 0.78 56.08 42.68 5.00
87 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
88 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 5.00
89 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
90 INT16323 Gene_expression of pr 62 0.66 36.14 38.26 5.00
91 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
92 INT6277 Positive_regulation of Gene_expression of Pomc 76 0.70 21.45 31.09 5.00
93 INT2884 Positive_regulation of CCK 66 0.69 25.25 30.6 5.00
94 INT67912 Gene_expression of GRIN1 75 0.77 28.99 29.28 5.00
95 INT91775 Gene_expression of Slc6a4 102 0.78 26.45 28.23 5.00
96 INT78251 Positive_regulation of LBP 38 0.69 39.98 26.73 5.00
97 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
98 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
99 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 5.00
100 INT57192 Binding of Ltp 43 0.41 17.48 24.96 5.00
101 INT1030 Localization of Lbp 52 0.74 38.92 24.91 5.00
102 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 5.00
103 INT58288 Positive_regulation of Gene_expression of Crp 83 0.61 82.23 23.7 5.00
104 INT7383 Localization of VIP 53 0.81 17.7 22.65 5.00
105 INT45437 Localization of Acot1 84 0.79 17.37 22.18 5.00
106 INT23257 Regulation of CRP 127 0.62 100.05 21.87 5.00
107 INT125312 Positive_regulation of COPD 134 0.59 162.55 20.27 5.00
108 INT12243 Positive_regulation of PRSS1 91 0.70 52.87 19.48 5.00
109 INT106097 Localization of pr 20 0.62 12.01 19.46 5.00
110 INT70970 Binding of COPD 144 0.42 180.34 18.29 5.00
111 INT38056 Localization of Crp 71 0.78 53.14 17.03 5.00
112 INT3400 Positive_regulation of pr 57 0.68 36.9 16.24 5.00
113 INT2243 Localization of GAST 67 0.81 34.54 16.19 5.00
114 INT36554 Gene_expression of PRSS1 70 0.78 50.25 15.33 5.00
115 INT2630 Positive_regulation of Shbg 134 0.70 65.26 15.19 5.00
116 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17 5.00
117 INT75540 Positive_regulation of TH1L 62 0.67 43.45 15.02 5.00
118 INT12369 Negative_regulation of Htr3a 28 0.59 8.78 12.62 5.00
119 INT69158 Localization of IL4 48 0.71 31.3 11.98 5.00
120 INT28872 Positive_regulation of CSRP1 49 0.70 47.23 11.7 5.00
121 INT3602 Negative_regulation of Shbg 148 0.53 69.05 11.65 5.00
122 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 5.00
123 INT58904 Localization of TH1L 40 0.68 27.11 10.52 5.00
124 INT3982 Gene_expression of Acot1 53 0.56 7.61 10.46 5.00
125 INT25989 Localization of Vip 31 0.68 10.53 10.35 5.00
126 INT95342 Gene_expression of GRIN2B 21 0.75 4.99 9.32 5.00
127 INT22798 Regulation of Shbg 64 0.60 26.71 8.76 5.00
128 INT6499 Localization of Ntrk2 44 0.79 11.78 8.75 5.00
129 INT52243 Phosphorylation of Ltp 13 0.54 2.84 8.7 5.00
130 INT75932 Binding of Csf2 45 0.37 33.2 8.01 5.00
131 INT15161 Positive_regulation of Localization of VIP 12 0.50 3.3 7.87 5.00
132 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58 5.00
133 INT95340 Gene_expression of GRIN2A 12 0.77 1.5 7.39 5.00
134 INT22782 Localization of PRSS1 25 0.81 14.44 7.34 5.00
135 INT124264 Regulation of Localization of Calca 10 0.33 1.39 7.14 5.00
136 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63 5.00
137 INT24946 Binding of PRSS1 23 0.47 16.75 6.41 5.00
138 INT118124 Binding of USE1 24 0.16 16.64 5.44 5.00
139 INT2132 Localization of SCT 29 0.81 8.39 5.43 5.00
140 INT1029 Positive_regulation of Gene_expression of Lbp 17 0.50 11.03 5.18 5.00
141 INT162249 Gene_expression of Hist1h2aa 8 0.12 6.46 4.35 5.00
142 INT45433 Positive_regulation of Localization of Acot1 18 0.45 1.9 4.32 5.00
143 INT12111 Negative_regulation of Hbb-ar 11 0.37 6.63 4.22 5.00
144 INT183207 Negative_regulation of USE1 14 0.18 10.97 4 5.00
145 INT19158 Gene_expression of PAH 35 0.65 35.81 3.88 5.00
146 INT62784 Gene_expression of NT5E 46 0.65 15.95 3.72 5.00
147 INT115227 Regulation of Localization of Acot1 12 0.60 0.15 3.51 5.00
148 INT12385 Localization of NGFR 6 0.81 3.05 3.47 5.00
149 INT206194 Transcription of Ltp 6 0.58 3.28 3.32 5.00
150 INT80779 Positive_regulation of Hbb-ar 10 0.41 2.48 3.29 5.00
151 INT9110 Binding of PAH 32 0.41 42.1 3.1 5.00
152 INT63902 Positive_regulation of Htr4 7 0.67 0.71 2.84 5.00
153 INT181267 Gene_expression of USE1 12 0.32 7.6 2.7 5.00
154 INT127458 Positive_regulation of PAH 24 0.58 27.25 2.53 5.00
155 INT184272 Binding of HMGB1 14 0.37 8.78 2.49 5.00
156 INT200217 Localization of PAH 10 0.36 15.51 2.46 5.00
157 INT25438 Positive_regulation of Positive_regulation of Pomc 6 0.48 4 2.37 5.00
158 INT79440 Localization of LEPROT 2 0.09 1.32 2.25 5.00
159 INT106307 Positive_regulation of UROD 27 0.49 16.63 2.19 5.00
160 INT3179 Positive_regulation of SCT 15 0.50 4.79 1.98 5.00
161 INT63901 Positive_regulation of Positive_regulation of Htr4 2 0.49 0.3 1.93 5.00
162 INT122195 Regulation of Localization of VEGFA 13 0.57 10.61 1.92 5.00
163 INT256260 Positive_regulation of Binding of Ltp 3 0.03 1.2 1.89 5.00
164 INT166311 Positive_regulation of Gene_expression of LBP 7 0.49 4.15 1.81 5.00
165 INT59790 Binding of BCR 16 0.36 15.34 1.75 5.00
166 INT101412 Negative_regulation of CDAN1 16 0.57 6.41 1.61 5.00
167 INT198663 Positive_regulation of HMGB1 14 0.52 11.41 1.58 5.00
168 INT96420 Positive_regulation of NT5E 9 0.49 3.7 1.38 5.00
169 INT120722 Gene_expression of TYMP 35 0.75 19.26 1.31 5.00
170 INT44817 Negative_regulation of Gene_expression of Shbg 9 0.34 9.84 1.11 5.00
171 INT135122 Binding of GJA8 3 0.11 2.08 0.97 5.00
172 INT257453 Positive_regulation of USE1 12 0.20 6.7 0.94 5.00
173 INT160599 Regulation of Gene_expression of LBP 2 0.44 1.23 0.92 5.00
174 INT2131 Positive_regulation of Localization of SCT 6 0.47 2.01 0.88 5.00
175 INT250645 Gene_expression of Samsn1 6 0.33 9.95 0.86 5.00
176 INT303465 Binding of KAR 1 0.03 0.25 0.84 5.00
177 INT220338 Positive_regulation of Gene_expression of UROD 2 0.49 3.55 0.69 5.00
178 INT132528 Gene_expression of TAPBP 17 0.65 5.93 0.69 5.00
179 INT204120 Positive_regulation of GJA8 2 0.30 1.51 0.63 5.00
180 INT159493 Binding of CDAN1 3 0.36 2.18 0.62 5.00
181 INT155035 Binding of NT5E 3 0.36 1.78 0.61 5.00
182 INT159494 Gene_expression of CDAN1 8 0.65 4.55 0.58 5.00
183 INT95550 Negative_regulation of Positive_regulation of ALB 4 0.42 1.16 0.57 5.00
184 INT134902 Positive_regulation of Tymp 11 0.37 3.06 0.53 5.00
185 INT220333 Binding of UROD 4 0.30 2.66 0.52 5.00
186 INT353015 Negative_regulation of Positive_regulation of AGTRAP 1 0.01 0.35 0.49 5.00
187 INT220339 Transcription of HMGB1 2 0.53 2.03 0.49 5.00
188 INT353018 Positive_regulation of AGTRAP 1 0.01 0.34 0.49 5.00
189 INT100731 Negative_regulation of Localization of PRSS1 2 0.14 2.17 0.47 5.00
190 INT96419 Positive_regulation of Gene_expression of NT5E 3 0.49 1.46 0.41 5.00
191 INT287129 Regulation of NT5E 3 0.12 1.02 0.32 5.00
192 INT247824 Positive_regulation of CDAN1 4 0.33 2.4 0.32 5.00
193 INT138556 Positive_regulation of TYMP 23 0.58 12.9 0.28 5.00
194 INT204128 Negative_regulation of GJA8 2 0.26 2.73 0.24 5.00
195 INT354726 Binding of Tymp 1 0.30 1.08 0.23 5.00
196 INT188242 Negative_regulation of Positive_regulation of CRP 4 0.23 3.94 0.22 5.00
197 INT211375 Regulation of Gene_expression of TYMP 2 0.43 2.44 0.22 5.00
198 INT201196 Negative_regulation of Gene_expression of PAH 2 0.30 3.11 0.19 5.00
199 INT132529 Binding of TAPBP 8 0.47 1.43 0.18 5.00
200 INT227040 Negative_regulation of CHRM2 5 0.14 1.67 0.15 5.00
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