D:Intractable Pain

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Disease Term
Synonyms Intractable Pains, PAIN REFRACTORY, Pains Intractable, Pains Refractory, REFRACTORY PAIN, Refractory Pains
Documents 1804
Hot Single Events 101
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Intractable Pain. They are ordered first by their relevance to Intractable Pain and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT166945 Ngf Positive_regulation of Trpv1 1 0.01 0.47 1.88 64.56
2 INT166947 Ngf Positive_regulation of KNG1 1 0.00 0.47 1.86 64.56
3 INT140660 Phax Negative_regulation of Trpv1 2 0.08 0.58 0.84 60.00
4 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11 58.84
5 INT317546 Oprm1 Regulation of Prkca 1 0.06 0.4 0.82 47.44
6 INT317513 Oprm1 Regulation of Positive_regulation of Src 1 0.09 0.4 0.82 47.44
7 INT317570 Oprm1 Regulation of Src 1 0.04 0.4 0.82 47.44
8 INT317573 Binding of Oprm1 and Pik3r1 1 0.12 0.33 0.71 43.24
9 INT317523 Oprm1 Positive_regulation of Gene_expression of Akt1 1 0.32 0.05 0.53 35.80
10 INT317574 Oprm1 Positive_regulation of Akt1 1 0.22 0.05 0.52 35.80
11 INT317565 Oprm1 Positive_regulation of Pik3r1 1 0.14 0.05 0.52 35.80
12 INT310066 Negative_regulation of Pain1 Positive_regulation of Faah 1 0.03 1.32 1.23 31.64
13 INT310069 Negative_regulation of Pain1 Positive_regulation of Mgll 1 0.02 1.32 1.23 31.64
14 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36 30.16
15 INT310068 Pain1 Positive_regulation of Faah 1 0.03 1.3 1.22 29.96
16 INT310067 Pain1 Positive_regulation of Mgll 1 0.02 1.29 1.21 28.60
17 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 5.00
18 INT317517 Binding of Nos1 and Oprm1 1 0.17 0.22 3.85 5.00
19 INT317511 Ppp1r9b Regulation of Oprm1 3 0.27 0.33 3.85 5.00
20 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13 5.00
21 INT317563 Binding of Hint1 and Oprm1 1 0.20 0.25 3.03 5.00
22 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74 5.00
23 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48 5.00
24 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41 5.00
25 INT317526 Binding of Hint1 and Gipc1 1 0.00 0.25 2.38 5.00
26 INT211748 Binding of Pag1 and Mors1 2 0.07 0.2 2.26 5.00
27 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21 5.00
28 INT140659 Phax Positive_regulation of Trpv1 3 0.49 0.68 2.18 5.00
29 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09 5.00
30 INT317540 Camk2a Negative_regulation of Oprm1 1 0.19 0 1.98 5.00
31 INT165183 Ifnb1 Positive_regulation of P2rx4 1 0.04 1.73 1.73 5.00
32 INT317558 Binding of Oprm1 and Rgs17 1 0.18 0 1.59 5.00
33 INT317538 Binding of Neu3 and Mors1 1 0.00 0 1.51 5.00
34 INT317509 Oprm1 Negative_regulation of Phosphorylation of Oprd1 1 0.00 0 1.46 5.00
35 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31 5.00
36 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29 5.00
37 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25 5.00
38 INT317553 Binding of Car2 and Grin1 1 0.07 0 1.14 5.00
39 INT317549 Negative_regulation of Camk2a Negative_regulation of Phosphorylation of Oprm1 1 0.19 0 1.14 5.00
40 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11 5.00
41 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11 5.00
42 INT317527 Binding of Hint1 and Nos1 1 0.27 0.1 1.11 5.00
43 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1 5.00
44 INT317561 Binding of Grin1 and Oprm1 1 0.14 0.09 1.08 5.00
45 INT317531 Regulation of Binding of Grin1 and Mors1 1 0.08 0.06 1.05 5.00
46 INT317534 Regulation of Binding of Camk2a and Grin1 1 0.20 0.06 1.05 5.00
47 INT317552 Binding of Calm3 and Car2 2 0.06 0.07 1.05 5.00
48 INT317535 Binding of Grin1 and Mors1 1 0.07 0.06 1.04 5.00
49 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1 5.00
50 INT317532 Grin1 Regulation of Negative_regulation of Oprm1 1 0.18 0.07 1 5.00
51 INT317518 Src Regulation of Negative_regulation of Oprm1 1 0.16 0.07 1 5.00
52 INT317555 Nos1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1 5.00
53 INT317544 Camk2a Regulation of Negative_regulation of Oprm1 1 0.20 0.07 1 5.00
54 INT317564 Pik3r1 Regulation of Negative_regulation of Oprm1 1 0.13 0.07 1 5.00
55 INT317568 Prkca Regulation of Negative_regulation of Oprm1 1 0.10 0.07 1 5.00
56 INT147506 Binding of Ncam1 and Gtf3a 1 0.03 0.88 0.99 5.00
57 INT317550 Binding of Hint1 and Rgs20 1 0.32 0.07 0.98 5.00
58 INT147504 Binding of Ncam1 and Gdnf 1 0.31 0.87 0.98 5.00
59 INT317529 Binding of Hint1 and Rgs17 1 0.32 0.07 0.98 5.00
60 INT317543 Pag1 Positive_regulation of Oprm1 1 0.12 0.73 0.97 5.00
61 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96 5.00
62 INT351311 Has1 Regulation of Gene_expression of MMP3 1 0.11 1.15 0.95 5.00
63 INT317559 Binding of Hint1 and Pla2g4a 1 0.01 0.06 0.94 5.00
64 INT147507 Binding of Ret and Gtf3a 1 0.03 0.81 0.92 5.00
65 INT147505 Binding of Ret and Gdnf 1 0.27 0.81 0.92 5.00
66 INT317541 Oprd1 Negative_regulation of Akt1 1 0.06 0 0.91 5.00
67 INT317530 Negative_regulation of Binding of Nos1 and Oprm1 1 0.21 0.06 0.9 5.00
68 INT277832 Binding of TNFRSF1B and NPEPPS 1 0.01 1.1 0.88 5.00
69 INT277831 Binding of TNFRSF1A and NPEPPS 1 0.01 1.1 0.87 5.00
70 INT317515 Binding of Hint1 and Prkca 1 0.13 0.17 0.87 5.00
71 INT351323 Nts Regulation of Localization of Calca 1 0.01 0.6 0.85 5.00
72 INT317556 Phosphorylation of Gopc Positive_regulation of Akt1 1 0.10 0.08 0.82 5.00
73 INT317514 Akt1 Regulation of Localization of Oprm1 1 0.21 0.07 0.82 5.00
74 INT281651 Phax Positive_regulation of Gene_expression of Trpv1 1 0.09 0.89 0.79 5.00
75 INT351322 Nts Regulation of Localization of Napa 1 0.01 0.56 0.77 5.00
76 INT317547 Src Positive_regulation of Positive_regulation of Grin1 1 0.17 0 0.72 5.00
77 INT317560 Binding of Pdpk1 and Pik3r1 1 0.13 0 0.65 5.00
78 INT318981 Binding of CALR and GOPC 1 0.03 0.77 0.64 5.00
79 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62 5.00
80 INT281650 Trpv1 Positive_regulation of Localization of Calca 1 0.12 0.71 0.61 5.00
81 INT178087 EDN1 Positive_regulation of MMP13 2 0.23 1.58 0.59 5.00
82 INT281648 Negative_regulation of Binding of Trpv1 and Fig4 1 0.14 0.69 0.55 5.00
83 INT281647 Binding of Trpv1 and Fig4 1 0.12 0.68 0.55 5.00
84 INT281649 Negative_regulation of Binding of Calca and Trpv1 1 0.13 0.67 0.54 5.00
85 INT216918 Binding of Ca2 and Abat 1 0.01 0.45 0.53 5.00
86 INT216919 Ngf Positive_regulation of Gene_expression of P2rx3 1 0.18 0.69 0.53 5.00
87 INT317537 Oprm1 Positive_regulation of Phosphorylation of Nos1 1 0.16 0 0.5 5.00
88 INT317521 Camk2a Negative_regulation of Binding of Calm3 1 0.11 0 0.43 5.00
89 INT161796 Binding of ECE1 and EDN1 2 0.21 2.23 0.34 5.00
90 INT317566 Car2 Positive_regulation of Camk2a 2 0.19 0.58 0.32 5.00
91 INT317545 Calm3 Positive_regulation of Camk2a 1 0.17 0 0.31 5.00
92 INT317557 Calm3 Positive_regulation of Car2 1 0.05 0 0.31 5.00
93 INT317571 Grin1 Regulation of Trpv1 1 0.00 0 0.29 5.00
94 INT317562 Binding of Grin1 and Gnptab 1 0.00 0 0.29 5.00
95 INT178102 EDNRA Positive_regulation of Localization of TIMP1 1 0.06 0.97 0.28 5.00
96 INT178088 EDNRA Positive_regulation of Transcription of TIMP1 1 0.06 0.97 0.28 5.00
97 INT317533 Akt1 Positive_regulation of Nos1 1 0.43 0 0.28 5.00
98 INT208499 Positive_regulation of Nkx1-1 Positive_regulation of Npr1 1 0.00 0 0.27 5.00
99 INT317510 Binding of Grin2a and Gnptab 1 0.00 0 0.26 5.00
100 INT178095 EDN1 Positive_regulation of MMP3 1 0.04 0.88 0.24 5.00
101 INT178076 EDN1 Positive_regulation of MMP2 1 0.04 0.88 0.24 5.00
102 INT178085 EDN1 Positive_regulation of MMP7 1 0.06 0.89 0.24 5.00
103 INT178141 EDN1 Positive_regulation of Timp1 1 0.30 0.89 0.24 5.00
104 INT178075 EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24 5.00
105 INT178104 EDN1 Positive_regulation of Localization of TIMP1 1 0.05 0.83 0.24 5.00
106 INT178094 Positive_regulation of EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24 5.00
107 INT178142 EDN1 Positive_regulation of Localization of Timp1 1 0.28 0.89 0.24 5.00
108 INT178077 EDN1 Positive_regulation of MMP9 1 0.06 0.88 0.24 5.00
109 INT318980 Binding of CALR and Positive_regulation of Localization of GOPC 1 0.04 0.32 0.24 5.00
110 INT178059 Binding of EDN1 and EDNRA Positive_regulation of Phosphorylation of PXN 1 0.04 0.83 0.2 5.00
111 INT178074 EDN1 Positive_regulation of Phosphorylation of PXN 1 0.05 0.82 0.2 5.00
112 INT178086 Binding of EDNRA and PTK2 1 0.07 0.82 0.2 5.00
113 INT178092 EDN3 Positive_regulation of PTK2 1 0.01 1.02 0.17 5.00
114 INT178073 EDN1 Positive_regulation of PTK2 1 0.03 1.02 0.17 5.00
115 INT178079 EDN1 Positive_regulation of Positive_regulation of AKT1 1 0.05 0.91 0.16 5.00
116 INT178083 EDN1 Positive_regulation of Gene_expression of VEGFA 1 0.09 1.8 0.13 5.00
117 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 0.03 1 0.12 5.00
118 INT341294 DRG1 Positive_regulation of Atf3 1 0.01 0 0.1 5.00
119 INT178089 Binding of EDNRA and Positive_regulation of PTK2 1 0.09 0.74 0.09 5.00
120 INT178072 Gene_expression of EDNRB Positive_regulation of EDN3 1 0.05 1.11 0.08 5.00
121 INT178100 Gene_expression of EDNRB Positive_regulation of EDN1 1 0.17 1.11 0.08 5.00
122 INT178081 Negative_regulation of EDN1 Positive_regulation of HIF1A 1 0.04 1.18 0.08 5.00
123 INT178078 Positive_regulation of Binding of DBP and HIF1A 1 0.00 1 0.08 5.00
124 INT178080 EDN1 Positive_regulation of HIF1A 1 0.05 1.05 0.08 5.00
125 INT178060 EDN1 Positive_regulation of EDN1 Positive_regulation of HIF1A 1 0.03 1.13 0.08 5.00
126 INT178103 Binding of DBP and HIF1A 1 0.00 0.99 0.07 5.00
127 INT178093 EDN3 Positive_regulation of Gene_expression of EDNRB 1 0.05 1.01 0.07 5.00
128 INT178096 EDN1 Positive_regulation of Gene_expression of EDNRB 1 0.17 1.01 0.07 5.00
129 INT178084 EDNRA Positive_regulation of Phosphorylation of GJA1 1 0.10 0.88 0.06 5.00
130 INT178090 EDN1 Positive_regulation of Phosphorylation of GJA1 1 0.09 0.88 0.06 5.00
131 INT178091 EDN1 Positive_regulation of Gene_expression of PTGER2 1 0.01 0.74 0.04 5.00
132 INT331172 Binding of IFNA1 and IL2 1 0.00 0.46 0.04 5.00
133 INT178098 EDN1 Positive_regulation of Transcription of VEGFA 1 0.08 0.76 0.04 5.00
134 INT232206 Binding of Tgfb1 and Tnfsf11 1 0.02 0.52 0.04 5.00
135 INT232207 Binding of Tgfb1 and Tnfrsf11a 1 0.02 0.51 0.04 5.00
136 INT178082 EDN1 Positive_regulation of VEGFA 1 0.08 0.77 0.04 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Intractable Pain. They are ordered first by their pain relevance and then by number of times they were reported in Intractable Pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT49520 Gene_expression of P2rx3 121 0.78 61.15 49.24 99.92
2 INT3840 Negative_regulation of FCGR3B 18 0.59 8.9 5.97 99.32
3 INT3841 Gene_expression of FCGR3B 117 0.75 58.99 28.87 99.32
4 INT11628 Regulation of Localization of Pomc 44 0.61 10.46 18.66 99.30
5 INT5674 Gene_expression of Adra2a 34 0.77 6.14 15.13 99.30
6 INT2289 Gene_expression of PENK 203 0.78 55.62 79.49 99.28
7 INT4880 Regulation of MME 17 0.61 7.78 8.2 99.16
8 INT1438 Localization of Pomc 360 0.81 101.26 116.47 99.08
9 INT6926 Regulation of Pag1 72 0.39 55.79 65.09 99.04
10 INT7800 Localization of Pag1 51 0.56 33.06 53.74 99.04
11 INT62510 Positive_regulation of MCS 32 0.60 11.79 5.45 99.04
12 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 98.88
13 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 98.76
14 INT19771 Positive_regulation of PAG1 69 0.61 75.61 76.88 98.56
15 INT1726 Positive_regulation of Kitl 65 0.70 38.81 44.85 98.56
16 INT87698 Gene_expression of WAS 25 0.58 8.75 11.83 98.20
17 INT13352 Regulation of Kitl 11 0.45 3.91 6.07 98.08
18 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87 97.72
19 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 97.60
20 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 97.16
21 INT27954 Positive_regulation of Gene_expression of Ngf 87 0.70 57.91 51.96 97.16
22 INT27955 Negative_regulation of Gene_expression of Ngf 16 0.59 10.43 10.17 97.16
23 INT146091 Negative_regulation of IFNAR1 6 0.25 9.12 4.86 96.96
24 INT163028 Negative_regulation of Negative_regulation of IFNAR1 1 0.05 0.86 0.73 96.96
25 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 96.88
26 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 96.64
27 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 96.48
28 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69 96.04
29 INT68882 Binding of P2rx7 16 0.23 4.33 6.17 96.04
30 INT91013 Binding of IFNAR1 9 0.46 8.7 2.74 95.80
31 INT18995 Binding of CEL 23 0.47 14.46 4.5 95.80
32 INT149703 Gene_expression of Insl3 1 0.40 2.27 1.02 95.64
33 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 95.60
34 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33 95.60
35 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92 95.24
36 INT20345 Gene_expression of Dbi 136 0.78 56.41 46.2 94.72
37 INT27266 Regulation of Gene_expression of Pomc 41 0.62 6.74 14.59 94.72
38 INT27642 Regulation of Gene_expression of Dbi 10 0.44 2.55 3.66 94.72
39 INT258932 Positive_regulation of TBX1 3 0.39 2.73 0.82 94.40
40 INT149314 Negative_regulation of CAV2 5 0.42 1.21 2.76 94.28
41 INT214073 Binding of TSC1 9 0.37 22 1.34 93.32
42 INT155150 Gene_expression of Spic 5 0.26 1.21 0.86 92.12
43 INT29144 Gene_expression of Rvm 41 0.52 29.23 47.76 92.00
44 INT57721 Localization of CCT6A 2 0.16 3.12 5.88 91.36
45 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 90.96
46 INT119523 Gene_expression of EDNRB 32 0.75 26.47 5.75 90.48
47 INT60776 Regulation of EDNRA 20 0.51 16.62 5.36 90.36
48 INT7133 Negative_regulation of MME 85 0.59 29.22 33.1 90.32
49 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 90.32
50 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 89.84
51 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 89.32
52 INT6852 Localization of TNF 883 0.81 705.95 270.84 89.20
53 INT148 Positive_regulation of Gnrhr 182 0.70 47.44 79.64 88.72
54 INT131848 Positive_regulation of Gene_expression of RHOC 9 0.64 15.43 1.36 88.36
55 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 88.32
56 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75 88.16
57 INT139580 Negative_regulation of Trpm8 19 0.58 3.8 6.26 88.16
58 INT6481 Binding of TNF 624 0.48 510.2 214.82 88.04
59 INT131850 Gene_expression of RHOC 17 0.72 29.06 2.28 87.96
60 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 87.96
61 INT97513 Localization of Mefv 6 0.71 8.14 1.55 87.92
62 INT17996 Binding of Crp 40 0.37 31.4 7.8 87.52
63 INT67822 Binding of SERPINH1 17 0.36 19.05 7.24 87.52
64 INT149704 Positive_regulation of Gene_expression of Insl3 1 0.30 0.57 0.24 87.04
65 INT230715 Regulation of KCNB1 1 0.14 0.64 1.02 86.16
66 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 86.08
67 INT161180 Regulation of Gene_expression of Rvm 3 0.17 3.95 4.23 86.00
68 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79 85.28
69 INT5989 Positive_regulation of Dbi 79 0.49 24.38 32.56 85.12
70 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 84.84
71 INT54978 Binding of EDNRA 36 0.41 14.97 7.86 84.80
72 INT64484 Binding of PNOC 12 0.33 5.51 10.86 84.32
73 INT163500 Transcription of Grin2b 3 0.67 3.63 3.8 84.04
74 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91 84.04
75 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 84.00
76 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42 84.00
77 INT23937 Gene_expression of EDNRA 103 0.65 55.63 24.67 83.80
78 INT23938 Positive_regulation of Gene_expression of EDNRA 8 0.45 9.82 1.47 83.80
79 INT812 Localization of INS 1026 0.81 515.6 145.31 83.72
80 INT131851 Positive_regulation of RHOC 3 0.57 9.44 0.41 82.92
81 INT88868 Binding of MCS 45 0.40 37.43 7.98 82.80
82 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 82.44
83 INT3823 Positive_regulation of ALPI 27 0.69 19.49 2.15 82.44
84 INT22812 Positive_regulation of PTRH1 4 0.49 3.06 0.43 82.44
85 INT443 Localization of POMC 1020 0.81 284.52 443.17 81.92
86 INT20210 Localization of Ngf 69 0.79 46.22 38.57 81.76
87 INT2884 Positive_regulation of CCK 66 0.69 25.25 30.6 81.60
88 INT2406 Gene_expression of CCK 85 0.78 28.04 46.67 81.60
89 INT78328 Positive_regulation of Gene_expression of CCK 5 0.70 3.84 4.38 81.60
90 INT78327 Positive_regulation of Positive_regulation of CCK 3 0.47 1.74 2.82 81.60
91 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 81.52
92 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 81.52
93 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93 81.52
94 INT53764 Gene_expression of SPN 5 0.75 5.62 0.38 81.52
95 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 81.48
96 INT21353 Binding of Mcf2l 3 0.38 1.03 0.43 81.36
97 INT14690 Localization of CSF2 124 0.80 85.17 27.26 81.32
98 INT3034 Localization of Ngf 126 0.81 50.81 72.84 81.00
99 INT2911 Positive_regulation of Glul 36 0.70 11.09 22.07 80.84
100 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61 80.60
101 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 80.12
102 INT11042 Localization of Tbxa2r 26 0.76 10.15 7.24 79.60
103 INT25386 Positive_regulation of Cd3e 30 0.62 13.91 3.41 79.52
104 INT101049 Positive_regulation of CD5 6 0.67 5.71 0.68 79.52
105 INT121388 Positive_regulation of BCL6 2 0.28 2.71 0.32 79.52
106 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 79.44
107 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 79.40
108 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 79.40
109 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05 79.40
110 INT43789 Localization of Spag11a 1 0.04 0.27 0.34 78.60
111 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4 78.48
112 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 78.40
113 INT161436 Transcription of F2 2 0.69 1.21 0.36 77.64
114 INT49701 Negative_regulation of Localization of Ngf 9 0.58 3.01 5.75 77.52
115 INT131849 Negative_regulation of RHOC 4 0.54 6.46 0.34 77.48
116 INT131852 Positive_regulation of Negative_regulation of RHOC 1 0.46 1.12 0.12 77.48
117 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 77.44
118 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 77.32
119 INT131847 Negative_regulation of Gene_expression of RHOC 2 0.39 1.38 0.12 77.28
120 INT61116 Positive_regulation of Ppara 119 0.69 58.62 21.6 76.80
121 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 76.80
122 INT170927 Negative_regulation of Ppara 27 0.54 13.58 5.12 76.80
123 INT22499 Regulation of Calca 42 0.62 17.32 28.02 76.64
124 INT2490 Regulation of Sct 44 0.62 9.45 13.11 76.64
125 INT32881 Binding of Igk 5 0.36 1.07 2.95 75.36
126 INT30638 Positive_regulation of Gene_expression of Dbi 17 0.69 4.63 8.28 75.00
127 INT25 Positive_regulation of LAMC2 19 0.67 8.64 7.06 75.00
128 INT81229 Binding of COL1A1 24 0.35 12.07 3.3 75.00
129 INT33857 Negative_regulation of NTS 6 0.42 4.98 3.07 75.00
130 INT85651 Positive_regulation of ACACA 17 0.67 4.73 8.63 73.96
131 INT64110 Positive_regulation of Gene_expression of Nos1 68 0.70 58.11 51.64 73.88
132 INT76469 Positive_regulation of Gene_expression of Prkca 18 0.46 7.9 13.36 73.88
133 INT92516 Positive_regulation of Gene_expression of Grin1 8 0.45 2.53 3.77 73.88
134 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43 73.00
135 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 72.88
136 INT326 Gene_expression of Gnrhr 105 0.76 35.87 34.93 72.88
137 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76 72.76
138 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97 72.56
139 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 72.16
140 INT317508 Binding of Hint1 1 0.40 1.37 6.31 71.12
141 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97 71.08
142 INT24078 Negative_regulation of Thtpa 9 0.05 3.55 2.82 70.84
143 INT151386 Negative_regulation of Emp1 3 0.31 2.99 1.38 70.84
144 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68 70.68
145 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 69.92
146 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 68.92
147 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 68.84
148 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46 68.72
149 INT4892 Positive_regulation of Gene_expression of Tacr1 56 0.69 25.64 34.69 68.72
150 INT68661 Positive_regulation of NTSR1 11 0.69 9.6 5.91 68.16
151 INT178133 Negative_regulation of Positive_regulation of EDNRA 2 0.35 2.18 0.88 67.80
152 INT27303 Binding of FCGR3B 26 0.46 5.15 3.86 67.56
153 INT41721 Negative_regulation of MTOR 40 0.58 32.49 2.83 67.44
154 INT41719 Gene_expression of MTOR 27 0.77 19.43 1.44 67.44
155 INT41722 Positive_regulation of Negative_regulation of MTOR 1 0.45 0.73 0.28 67.44
156 INT41720 Positive_regulation of Gene_expression of MTOR 2 0.49 1.54 0.28 67.44
157 INT52775 Positive_regulation of Phax 15 0.42 6.87 11.45 67.28
158 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66 67.12
159 INT23609 Negative_regulation of Acp5 5 0.33 1.69 1.65 66.96
160 INT23610 Gene_expression of Acp5 4 0.51 0.96 1.23 66.96
161 INT41718 Positive_regulation of Gene_expression of Acp5 1 0.38 0.73 0.28 66.96
162 INT70905 Positive_regulation of EDNRA 49 0.67 24.33 11.79 66.88
163 INT8101 Binding of INCENP 42 0.31 16.2 6.68 66.44
164 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 65.48
165 INT310061 Negative_regulation of Negative_regulation of Rorb 1 0.01 1.03 0.84 64.96
166 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 64.44
167 INT14853 Negative_regulation of Tac1 80 0.59 30.87 45.06 64.44
168 INT12476 Negative_regulation of TRPV1 124 0.59 47.95 77.98 64.32
169 INT2290 Protein_catabolism of POMC 41 0.99 4.86 23.36 64.24
170 INT30444 Negative_regulation of Protein_catabolism of POMC 4 0.51 2.11 4.53 64.24
171 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19 63.92
172 INT200369 Negative_regulation of Rorb 6 0.07 3.76 1.62 63.80
173 INT103666 Regulation of Mors1 20 0.28 3.6 18.86 63.76
174 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 63.40
175 INT121387 Negative_regulation of Gene_expression of CD5 3 0.40 2.6 0.25 62.88
176 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 62.72
177 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 62.72
178 INT97063 Gene_expression of CD5 16 0.77 13.81 3.13 62.56
179 INT322756 Negative_regulation of Tsc1 1 0.07 1.4 0.26 61.68
180 INT97779 Negative_regulation of TSC2 3 0.41 3.45 0.26 61.68
181 INT67682 Localization of Bdnf 204 0.81 72.36 88.92 61.20
182 INT96299 Positive_regulation of Localization of Bdnf 35 0.70 15.67 16.09 61.20
183 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 60.92
184 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 60.92
185 INT158603 Positive_regulation of Gene_expression of P2RX4 7 0.55 5.85 4.56 60.48
186 INT264884 Gene_expression of LIMA1 1 0.65 0.68 0.06 60.36
187 INT15044 Localization of Nts 30 0.75 4.58 13.72 59.84
188 INT41727 Negative_regulation of Localization of Nts 3 0.39 1.48 3.15 59.84
189 INT82882 Localization of Ccl2 61 0.80 41.96 28 59.64
190 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8 59.04
191 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 58.92
192 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66 58.72
193 INT85326 Positive_regulation of Aqp1 7 0.65 5.9 3.71 58.68
194 INT1977 Negative_regulation of Positive_regulation of Prl 98 0.59 17.06 47.88 58.40
195 INT327 Negative_regulation of Positive_regulation of Gnrhr 17 0.53 4.22 10.21 58.40
196 INT184803 Localization of TSC1 5 0.37 6.13 0.32 58.24
197 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 58.24
198 INT129157 Positive_regulation of Atf3 48 0.69 35.42 22.87 58.24
199 INT171962 Gene_expression of Tnfrsf11a 40 0.72 31.1 7.84 58.24
200 INT199480 Positive_regulation of DRG1 3 0.02 3.22 2.51 58.00
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