D:Iron Overload

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Excess Iron, EXCESSIVE IRON, Haem Overload, HAEMOCHROMATOSIS, HEME OVERLOAD, Hemochromatosis, Increased Storage Of Iron, IRON EXCESS, Overload Iron
Documents 323
Hot Single Events 200
Hot Interactions 16

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Iron Overload. They are ordered first by their relevance to Iron Overload and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT242858 Binding of HFE and INS 1 0.06 1.64 0 100.00
2 INT238826 Binding of INS and RBP4 1 0.10 2.07 0 99.22
3 INT338789 HFE2 Regulation of HAMP 1 0.11 1 0.09 98.60
4 INT306925 IL36RN Positive_regulation of HAMP 1 0.01 1.39 0.1 98.16
5 INT306924 IL6 Positive_regulation of HAMP 1 0.02 1.38 0.1 98.16
6 INT338787 SYCP3 Regulation of HAMP 1 0.11 0.27 0.04 97.88
7 INT315538 Negative_regulation of GLRX5 Negative_regulation of Gene_expression of SLC40A1 1 0.25 1.14 0 97.48
8 INT338788 TMPRSS6 Regulation of HAMP 1 0.10 0.27 0.04 94.24
9 INT315533 Negative_regulation of GLRX5 Negative_regulation of Gene_expression of ALAS2 1 0.38 1.06 0 94.08
10 INT288701 Epas1 Regulation of Transcription of Slc11a2 1 0.29 0.38 0.13 90.56
11 INT283428 Negative_regulation of Binding of Lcn2 and Nt5e 1 0.06 1.09 0.15 89.92
12 INT204159 Slc11a2 Regulation of Gene_expression of HAMP 1 0.11 1.08 0.14 87.12
13 INT283432 Lcn2 Negative_regulation of Binding of Lcn2 and Nt5e 1 0.07 0.38 0 86.32
14 INT283426 Binding of Lcn2 and Nt5e 1 0.08 5.8 1.24 84.80
15 INT252807 Binding of ACO1 and TFRC 1 0.01 1.83 0 82.48
16 INT252791 Binding of IREB2 and TFRC 1 0.02 1.82 0 82.08
17 INT315535 Binding of ABCB7 and FECH 1 0.28 0.7 0 73.80
18 INT255166 Binding of MOCS1 and MPO 1 0.00 0.7 0.05 73.68
19 INT315532 Binding of NFS1 and ISCU 1 0.19 0.37 0 70.28
20 INT338827 Binding of Slc40a1 and HAMP 1 0.00 0.27 0.05 70.16
21 INT301670 Binding of CYP4F2 and Cyp4f18 1 0.02 1.04 0.27 70.08
22 INT315543 NARFL Regulation of Gene_expression of HIF1A 1 0.01 0.63 0 68.80
23 INT258861 Binding of HLA-DOA and HLA-DRB1 2 0.14 1.88 0.28 67.52
24 INT258909 Binding of HLA-DOA and NDUFA2 1 0.03 1.44 0.15 67.52
25 INT301668 Ltb4r1 Positive_regulation of Gene_expression of IL8 1 0.00 0.9 0.27 60.40
26 INT301671 Ltc4s Positive_regulation of Gene_expression of IL8 1 0.00 0.9 0.27 60.40
27 INT258906 Binding of HLA-B and HLA-DRB1 1 0.31 1.36 0.15 60.00
28 INT347414 Tlr4 Negative_regulation of Gpx1 1 0.01 0.36 0.04 56.16
29 INT347416 Tlr4 Negative_regulation of SOD1 1 0.00 0.36 0.04 56.16
30 INT318132 Binding of ATRX and HBE1 1 0.00 1.47 0 40.56
31 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18 26.24
32 INT120203 Binding of App and Il1 1 0.17 1.28 0.59 26.24
33 INT120204 Binding of App and Il1f5 1 0.09 1.28 0.59 26.24
34 INT120206 Binding of UTS2R and Il1 1 0.17 1.28 0.59 26.24
35 INT120207 Binding of UTS2R and Il1f5 1 0.09 1.28 0.59 26.24
36 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 5.00
37 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89 5.00
38 INT186672 IL8 Positive_regulation of Transcription of PTH 1 0.01 1.83 0.85 5.00
39 INT100783 Binding of CYP2B6 and CYP3A4 2 0.17 2 0.77 5.00
40 INT186674 Binding of BGLAP and CYP27A1 1 0.01 1.91 0.71 5.00
41 INT252772 ELANE Regulation of Gene_expression of CCL2 1 0.05 2.16 0.62 5.00
42 INT252826 ROS1 Regulation of Gene_expression of CCL2 1 0.20 2.17 0.62 5.00
43 INT146871 Tlr4 Positive_regulation of Gene_expression of ROS1 2 0.00 1.16 0.56 5.00
44 INT306935 Tnfsf12 Positive_regulation of Gene_expression of Cxcl10 1 0.03 3.55 0.55 5.00
45 INT283434 Lcn2 Positive_regulation of Localization of IL8 1 0.07 1.33 0.51 5.00
46 INT306936 Binding of Tnfsf12 and Tnfrsf12a 1 0.05 4.84 0.45 5.00
47 INT241853 Binding of SLC40A1 and HAMP 3 0.41 5.35 0.43 5.00
48 INT186673 IL8 Positive_regulation of Positive_regulation of PTH 1 0.01 0.92 0.42 5.00
49 INT288700 Binding of Cp and Tfrc 1 0.40 0 0.39 5.00
50 INT301665 CYP2C9 Regulation of Binding of Ppara 1 0.26 1.79 0.34 5.00
51 INT190683 Binding of A2M and INS 4 0.11 4.97 0.32 5.00
52 INT311997 Regulation of STAM Regulation of BGLAP 1 0.00 0.61 0.32 5.00
53 INT311991 STAM Regulation of BGLAP 1 0.00 0.61 0.31 5.00
54 INT301666 Binding of CYP4F2 and Ltb4r1 1 0.02 0.57 0.28 5.00
55 INT252806 F2 Positive_regulation of Gene_expression of CCL2 1 0.01 0.8 0.27 5.00
56 INT306941 Tnfsf12 Positive_regulation of Gene_expression of CCL2 1 0.03 1.65 0.27 5.00
57 INT306937 Tnfsf12 Positive_regulation of Gene_expression of Vcam1 1 0.05 1.79 0.27 5.00
58 INT306942 Tnfsf12 Positive_regulation of Gene_expression of ICAM1 1 0.04 1.78 0.27 5.00
59 INT252794 Binding of IL8 and TNF 1 0.02 0.75 0.25 5.00
60 INT252795 IL8 Positive_regulation of Positive_regulation of FOS 1 0.01 0.75 0.25 5.00
61 INT252815 Binding of CCL5 and TNF 1 0.02 0.75 0.25 5.00
62 INT252822 CCL2 Positive_regulation of Positive_regulation of FOS 1 0.04 0.75 0.25 5.00
63 INT252804 TNF Regulation of Positive_regulation of FOS 1 0.01 0.76 0.25 5.00
64 INT252786 CCL2 Regulation of Positive_regulation of FOS 1 0.05 0.75 0.25 5.00
65 INT252816 IL8 Regulation of Positive_regulation of FOS 1 0.01 0.75 0.25 5.00
66 INT252793 TNF Positive_regulation of Positive_regulation of FOS 1 0.02 0.76 0.25 5.00
67 INT252784 ROS1 Positive_regulation of Gene_expression of COL1A1 1 0.05 1.86 0.24 5.00
68 INT252777 ROS1 Positive_regulation of Gene_expression of CCL2 1 0.31 0.77 0.23 5.00
69 INT273024 Binding of FXYD1 and RLS 1 0.04 1.24 0.21 5.00
70 INT252787 Binding of FCGR3B and ROS1 1 0.06 0.58 0.2 5.00
71 INT252814 ELANE Positive_regulation of Positive_regulation of CCL2 1 0.05 0.8 0.2 5.00
72 INT283429 Nt5e Regulation of Gene_expression of Cxcr1 1 0.00 0.22 0.2 5.00
73 INT283431 Lcn2 Regulation of Gene_expression of Cxcr1 1 0.01 0.22 0.2 5.00
74 INT252782 ROS1 Positive_regulation of Positive_regulation of CCL2 1 0.22 0.8 0.2 5.00
75 INT327112 HCCS Positive_regulation of Gene_expression of SLCO1B3 1 0.03 0.65 0.19 5.00
76 INT252821 Binding of CD4 and IL12A 1 0.02 1.36 0.19 5.00
77 INT252817 Binding of CD8A and IL12A 1 0.02 1.36 0.19 5.00
78 INT252788 Binding of IL12A and IL18 1 0.01 1.33 0.19 5.00
79 INT301615 Binding of Cyp2e1 and Samsn1 1 0.02 2.42 0.18 5.00
80 INT291041 IL6 Regulation of IL36RN 1 0.00 1.09 0.17 5.00
81 INT238825 LTF Regulation of Localization of RBP4 1 0.05 1.08 0.16 5.00
82 INT301638 Ppara Regulation of Slc27a2 1 0.30 0.29 0.14 5.00
83 INT252785 ELANE Regulation of Gene_expression of FBRS 1 0.00 0.5 0.13 5.00
84 INT186243 IL36RN Positive_regulation of B4GALNT1 1 0.00 0.43 0.12 5.00
85 INT182886 Ros1 Positive_regulation of Mapk8 3 0.09 2.3 0.12 5.00
86 INT252779 Binding of ESR1 and RAF1 1 0.01 2.03 0.11 5.00
87 INT252778 RAF1 Positive_regulation of Positive_regulation of ROS1 1 0.04 2.05 0.11 5.00
88 INT301637 Positive_regulation of Ros1 Positive_regulation of Phosphorylation of Ins1 1 0.00 0.91 0.1 5.00
89 INT294451 KLK4 Negative_regulation of IL8 1 0.01 0 0.1 5.00
90 INT294449 KLK4 Negative_regulation of MMP9 1 0.01 0 0.1 5.00
91 INT186240 Binding of AGRP and SCN5A 2 0.13 1.19 0.1 5.00
92 INT294445 KLK4 Negative_regulation of COL1A1 1 0.01 0 0.1 5.00
93 INT294440 KLK4 Negative_regulation of LIF 1 0.00 0 0.1 5.00
94 INT294456 KLK4 Negative_regulation of SERPINB2 1 0.01 0 0.1 5.00
95 INT294446 KLK4 Negative_regulation of HAS2 1 0.01 0 0.1 5.00
96 INT294454 KLK4 Negative_regulation of PTGS2 1 0.01 0 0.1 5.00
97 INT294441 KLK4 Negative_regulation of CXCR4 1 0.01 0 0.1 5.00
98 INT294452 KLK4 Negative_regulation of CCL4 1 0.00 0 0.1 5.00
99 INT294438 KLK4 Negative_regulation of IL1A 1 0.00 0 0.1 5.00
100 INT240903 Mapk8 Positive_regulation of Ros1 2 0.09 1.01 0.1 5.00
101 INT186246 Binding of CAT and SCN5A 1 0.03 0.47 0.1 5.00
102 INT294437 KLK4 Negative_regulation of CXCL1 1 0.00 0 0.1 5.00
103 INT186242 Binding of ALB and SCN5A 1 0.04 0.36 0.1 5.00
104 INT294453 KLK4 Negative_regulation of CCL2 1 0.00 0 0.1 5.00
105 INT294442 KLK4 Negative_regulation of IL6 1 0.00 0 0.1 5.00
106 INT294455 KLK4 Negative_regulation of HIF1A 1 0.01 0 0.1 5.00
107 INT294450 KLK4 Negative_regulation of SERPINE1 1 0.01 0 0.1 5.00
108 INT186245 Binding of AGRP and CAT 1 0.02 0.53 0.1 5.00
109 INT294457 KLK4 Negative_regulation of MMP2 1 0.01 0 0.1 5.00
110 INT294448 KLK4 Negative_regulation of CTGF 1 0.01 0 0.1 5.00
111 INT294439 KLK4 Negative_regulation of THBS1 1 0.01 0 0.1 5.00
112 INT252790 Binding of NOS1 and NOS3 1 0.03 0.37 0.1 5.00
113 INT294443 KLK4 Negative_regulation of CXCL5 1 0.00 0 0.1 5.00
114 INT190684 Binding of A2M and IGF1 1 0.16 1.54 0.1 5.00
115 INT186244 Binding of AGRP and ALB 1 0.03 0.53 0.1 5.00
116 INT294444 KLK4 Negative_regulation of CCL3 1 0.00 0 0.1 5.00
117 INT301660 Ppara Regulation of Gene_expression of CYP4A11 1 0.24 0.65 0.09 5.00
118 INT311990 FCGR3B Regulation of STAM 1 0.01 0.27 0.09 5.00
119 INT199667 Cep290 Regulation of Atf4 1 0.04 1.96 0.09 5.00
120 INT252803 Binding of NOS3 and ISYNA1 1 0.02 0.32 0.09 5.00
121 INT283427 Lcn2 Positive_regulation of Nt5e 1 0.08 0.21 0.09 5.00
122 INT301663 Ppara Regulation of CYP4A11 1 0.14 0.65 0.09 5.00
123 INT199666 Cntln Regulation of Atf4 1 0.00 1.95 0.09 5.00
124 INT282684 FECH Positive_regulation of Negative_regulation of Ssbp3 1 0.00 1.54 0.08 5.00
125 INT301655 Irs1 Negative_regulation of Transcription of Pck1 1 0.03 0.65 0.08 5.00
126 INT301641 Irs2 Negative_regulation of Transcription of Pck1 1 0.03 0.65 0.08 5.00
127 INT301619 Positive_regulation of Irs1 Positive_regulation of Gene_expression of Srebf1 1 0.10 0.67 0.08 5.00
128 INT301628 Irs2 Negative_regulation of Transcription of G6pc 1 0.04 0.65 0.08 5.00
129 INT301646 Srebf1 Negative_regulation of Gene_expression of Irs2 1 0.08 0.62 0.08 5.00
130 INT301613 Binding of Fabp4 and Cd36 1 0.05 0.38 0.08 5.00
131 INT301645 Binding of Alb and Slc27a1 1 0.02 0.38 0.08 5.00
132 INT291040 Binding of CFH and INS 1 0.25 1.32 0.08 5.00
133 INT301631 Gene_expression of Mapk8 Positive_regulation of Phosphorylation of Irs1 1 0.09 0.72 0.08 5.00
134 INT301651 Binding of Alb and Fabp4 1 0.01 0.38 0.08 5.00
135 INT301649 Irs1 Negative_regulation of Transcription of G6pc 1 0.05 0.65 0.08 5.00
136 INT301614 Binding of Slc27a1 and Cd36 1 0.09 0.38 0.08 5.00
137 INT301659 Gene_expression of Mapk8 Positive_regulation of Positive_regulation of Srebf1 1 0.33 0.8 0.08 5.00
138 INT301656 Ins1 Positive_regulation of Srebf1 1 0.02 0.73 0.07 5.00
139 INT301623 Ins1 Positive_regulation of Slc27a2 1 0.01 0.37 0.07 5.00
140 INT283425 Lcn2 Positive_regulation of Gene_expression of Nt5e 1 0.07 0.13 0.07 5.00
141 INT283433 Nt5e Positive_regulation of Localization of IL8 1 0.01 0.21 0.07 5.00
142 INT301632 Binding of Dbi and Fabp1 1 0.13 0.49 0.07 5.00
143 INT301658 Ins1 Positive_regulation of Slc27a4 1 0.01 0.37 0.07 5.00
144 INT311994 Binding of FCGR3B and Positive_regulation of TNF 1 0.52 0 0.06 5.00
145 INT237670 SQSTM1 Regulation of PDB1 1 0.34 1.13 0.06 5.00
146 INT252823 Binding of TNF and SIGMAR1 1 0.01 0.95 0.05 5.00
147 INT301496 PPA1 Negative_regulation of CYP4F3 1 0.01 0.69 0.05 5.00
148 INT203638 Binding of MR1 and GOPC 1 0.04 1.43 0.05 5.00
149 INT301497 UBXN11 Negative_regulation of CYP4F3 1 0.37 0.69 0.05 5.00
150 INT301653 Mlxipl Positive_regulation of Gene_expression of Scd1 1 0.08 0.5 0.05 5.00
151 INT232814 Mocos Positive_regulation of Gene_expression of Tlr4 1 0.19 0.9 0.05 5.00
152 INT252801 PPP2R4 Regulation of Positive_regulation of CREB1 1 0.01 2.71 0.04 5.00
153 INT252797 ROS1 Positive_regulation of Positive_regulation of FAS 1 0.08 1.03 0.04 5.00
154 INT227072 Binding of LTF and PTPRC 1 0.00 0.51 0.04 5.00
155 INT252780 Positive_regulation of CREB1 Positive_regulation of PPP2R4 1 0.01 2.71 0.04 5.00
156 INT301627 Binding of Fabp1 and Ppara 1 0.21 0.49 0.04 5.00
157 INT252768 TNF Regulation of Tnfrsf1a 1 0.01 1.02 0.04 5.00
158 INT301661 Binding of CYP2B6 and Ros1 1 0.02 0.64 0.04 5.00
159 INT199212 Binding of IGFBP1 and INS 1 0.05 1.77 0.04 5.00
160 INT252818 PPP2R4 Regulation of Positive_regulation of DDIT3 1 0.04 3.07 0.04 5.00
161 INT252808 TNF Positive_regulation of NOX1 1 0.06 1.03 0.04 5.00
162 INT301647 Negative_regulation of Mapk8 Positive_regulation of Irs1 1 0.08 0.83 0.04 5.00
163 INT301626 Mapk8 Positive_regulation of Irs1 1 0.09 0.83 0.04 5.00
164 INT252767 CAT Regulation of Gpx1 1 0.00 0.25 0.04 5.00
165 INT301643 Binding of Dbi and fa 1 0.05 0.45 0.03 5.00
166 INT334918 GNRH1 Positive_regulation of Gene_expression of FSHR 2 0.11 1.27 0.03 5.00
167 INT301667 Tlr4 Positive_regulation of Gene_expression of CYBB 1 0.01 0.84 0.03 5.00
168 INT301662 Binding of Tlr4 and Positive_regulation of Gene_expression of CYBB 1 0.01 0.84 0.03 5.00
169 INT186249 Binding of ROS1 and SCN5A 1 0.09 0.73 0.03 5.00
170 INT311995 FCGR3B Regulation of Gene_expression of TNF 1 0.46 0 0.03 5.00
171 INT246480 Binding of ALB and SHBG 2 0.14 1.45 0.03 5.00
172 INT199665 Binding of Fxn and Lamtor3 1 0.00 0.16 0.03 5.00
173 INT301622 Binding of Fabp4 and fa 1 0.01 0.45 0.03 5.00
174 INT252820 ELANE Positive_regulation of Gene_expression of COL1A1 1 0.01 0.58 0 5.00
175 INT170885 Binding of PRSS1 and RHBDD2 1 0.01 0.4 0 5.00
176 INT289293 Binding of CD59 and Cd33 1 0.02 1.06 0 5.00
177 INT186502 Binding of AMELX and HLA-A 1 0.00 0.71 0 5.00
178 INT258908 Binding of BSG and HLA-DQA1 1 0.00 0.1 0 5.00
179 INT186248 NR5A1 Positive_regulation of Transcription of STAR 1 0.01 0.21 0 5.00
180 INT252774 ROS1 Regulation of FUT1 1 0.04 0.57 0 5.00
181 INT334921 GNRHR Positive_regulation of Gene_expression of CGA 1 0.01 0.53 0 5.00
182 INT301633 Binding of Ros1 and Cyb5 1 0.00 0.41 0 5.00
183 INT311992 Binding of FCGR3B and STAM 1 0.02 0 0 5.00
184 INT238819 Binding of LTF and RBP4 1 0.04 0.26 0 5.00
185 INT232817 Mocos Negative_regulation of Positive_regulation of Gpt 1 0.29 0.34 0 5.00
186 INT238823 LTF Positive_regulation of GOPC 1 0.01 0.29 0 5.00
187 INT267329 Binding of SFSWAP and Apo 1 0.00 0.3 0 5.00
188 INT338783 Binding of SEA and TMPRSS6 1 0.06 0 0 5.00
189 INT301640 Positive_regulation of Cyp2e1 Positive_regulation of Gene_expression of Ros1 1 0.03 0.25 0 5.00
190 INT252810 ROS1 Regulation of Gene_expression of MMRN1 1 0.04 0.16 0 5.00
191 INT252796 ELANE Regulation of COL1A1 1 0.01 0.57 0 5.00
192 INT338781 Gene_expression of TMPRSS6 Negative_regulation of HAMP 1 0.11 0 0 5.00
193 INT273482 Binding of CYSLTR1 and USE1 1 0.00 0.77 0 5.00
194 INT241852 Binding of EPO and EPCAM 1 0.06 0.84 0 5.00
195 INT255164 Regulation of PM20D2 Regulation of FLNA 1 0.00 0.82 0 5.00
196 INT338828 Binding of Trf and TMPRSS6 1 0.05 0.1 0 5.00
197 INT289301 Binding of CD59 and Cd24a 1 0.02 1.06 0 5.00
198 INT334922 GNRHR Positive_regulation of Gene_expression of PLOD1 1 0.08 0.53 0 5.00
199 INT338791 TMPRSS6 Regulation of Gene_expression of HAMP 1 0.18 0 0 5.00
200 INT186239 Binding of ROS1 and Positive_regulation of PDE2A 1 0.00 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Iron Overload. They are ordered first by their pain relevance and then by number of times they were reported in Iron Overload. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT242865 Binding of HFE 7 0.42 6.01 0.12 100.00
2 INT58456 Gene_expression of HFE 10 0.58 7.68 1.65 100.00
3 INT45238 Gene_expression of Hfe 3 0.71 2.16 0.21 100.00
4 INT106127 Negative_regulation of CASR 7 0.43 7.12 0.67 100.00
5 INT67093 Binding of CASR 3 0.41 3.32 0.64 100.00
6 INT258917 Localization of HLA-H 1 0.48 1.18 0.09 100.00
7 INT258920 Regulation of CASR 3 0.22 2.02 0.18 100.00
8 INT315592 Positive_regulation of Gene_expression of SLC40A1 1 0.41 3.52 0 100.00
9 INT112215 Binding of Vdr 4 0.31 2.43 0.44 100.00
10 INT242866 Regulation of HFE 2 0.39 1.84 0 100.00
11 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 100.00
12 INT89026 Positive_regulation of Nt5e 12 0.49 7.25 2.67 100.00
13 INT64465 Positive_regulation of Reg3b 5 0.69 8.36 0.99 99.98
14 INT232406 Positive_regulation of DFP 1 0.28 1.29 0.06 99.96
15 INT10049 Negative_regulation of SERPINA1 56 0.59 44.52 9.93 99.92
16 INT315621 Gene_expression of CIAO1 1 0.34 4.11 0 99.90
17 INT315567 Positive_regulation of Negative_regulation of CIAO1 1 0.22 1.29 0 99.90
18 INT315572 Positive_regulation of ACO1 1 0.20 0.94 0 99.88
19 INT23620 Negative_regulation of C4A 24 0.57 15.1 2.23 99.88
20 INT183042 Localization of HFE 2 0.56 1.35 0.12 99.82
21 INT3895 Positive_regulation of Positive_regulation of Gcg 2 0.49 0.8 0.18 99.76
22 INT3893 Positive_regulation of Regulation of Gcg 1 0.46 0.8 0.09 99.76
23 INT315559 Negative_regulation of CIAO1 1 0.19 2.53 0 99.74
24 INT33466 Negative_regulation of C4B 14 0.43 9.06 4.64 99.70
25 INT310529 Positive_regulation of MDFIC 1 0.05 6.21 0.52 99.58
26 INT4436 Gene_expression of ABCB7 7 0.65 9.26 0.93 99.48
27 INT35431 Regulation of DFP 3 0.25 1.33 1.97 99.48
28 INT3658 Regulation of Gcg 28 0.53 12.89 8.58 99.40
29 INT2586 Positive_regulation of Gcg 35 0.70 9.25 11.75 99.40
30 INT64463 Positive_regulation of Transcription of Reg3b 1 0.46 1.39 0.15 99.36
31 INT14902 Negative_regulation of XDH 38 0.55 24.19 2.86 99.36
32 INT179373 Localization of XDH 3 0.20 1.97 0.54 99.36
33 INT218314 Binding of RBP4 9 0.36 6.27 0.33 99.22
34 INT72782 Positive_regulation of HCC 41 0.40 63.74 2.46 99.14
35 INT170886 Gene_expression of AIRE 2 0.49 4.63 0.19 99.12
36 INT251 Regulation of INS 398 0.62 232.47 55.04 98.82
37 INT218315 Gene_expression of RBP4 25 0.76 18.19 0.85 98.82
38 INT673 Positive_regulation of B2m 24 0.68 24.24 4.82 98.72
39 INT47095 Positive_regulation of Naglu 3 0.66 1.5 0.53 98.72
40 INT315587 Positive_regulation of Gene_expression of CIAO1 1 0.22 1.6 0 98.60
41 INT338801 Binding of HFE2 1 0.36 0.55 0.04 98.60
42 INT1473 Localization of Gcg 95 0.80 17.35 30.31 98.48
43 INT176202 Gene_expression of Abcb4 6 0.68 5.25 0.52 98.48
44 INT64466 Transcription of Reg3b 1 0.53 11.89 1.16 98.40
45 INT155822 Localization of ADH1A 3 0.78 3.74 0.32 98.26
46 INT3322 Positive_regulation of Gene_expression of ALAS2 4 0.43 3.25 0 98.20
47 INT306940 Positive_regulation of HAMP 3 0.49 5.06 0.36 98.16
48 INT238830 Positive_regulation of Localization of RBP4 1 0.68 2.98 0 98.12
49 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 98.08
50 INT7207 Regulation of HBG1 27 0.60 22.1 1.12 98.04
51 INT338798 Protein_catabolism of HFE2 1 0.37 0.52 0.08 98.04
52 INT315562 Gene_expression of GLRX5 1 0.69 4.92 0 98.00
53 INT243268 Gene_expression of SLC40A1 6 0.60 4.18 0.13 98.00
54 INT315607 Positive_regulation of Gene_expression of GLRX5 1 0.61 2.28 0 98.00
55 INT47550 Gene_expression of Naglu 4 0.44 2.02 0.23 98.00
56 INT64464 Gene_expression of Reg3b 4 0.77 10.95 2.77 97.92
57 INT64458 Negative_regulation of Transcription of Reg3b 1 0.37 1.43 0.13 97.92
58 INT3894 Negative_regulation of Localization of Gcg 18 0.52 2.7 5.77 97.88
59 INT218313 Localization of RBP4 5 0.79 15.68 1.4 97.64
60 INT308962 Regulation of SLC7A7 3 0.16 1.2 0.18 97.64
61 INT218316 Positive_regulation of RBP4 2 0.68 7.54 0.3 97.64
62 INT64378 Gene_expression of DMRT1 9 0.54 1.72 1.71 97.64
63 INT345677 Negative_regulation of Gene_expression of DMRT1 1 0.04 0.17 0 97.64
64 INT345684 Transcription of DMRT1 1 0.05 0.17 0 97.64
65 INT22597 Positive_regulation of TF 43 0.68 27.27 5.17 97.60
66 INT95756 Gene_expression of ACO1 3 0.27 2.49 0.1 97.52
67 INT115264 Binding of FECH 9 0.41 7.93 1.1 97.48
68 INT105021 Binding of GOPC 187 0.40 60.39 20.38 97.48
69 INT315565 Negative_regulation of Gene_expression of SLC40A1 1 0.25 1.73 0 97.48
70 INT64462 Negative_regulation of Reg3b 1 0.37 1.43 0.13 97.44
71 INT131139 Binding of ACO1 3 0.27 1.81 0.1 97.20
72 INT159518 Gene_expression of Clock 4 0.35 2.34 6.91 97.12
73 INT80486 Gene_expression of FECH 13 0.54 10.42 4.8 97.04
74 INT338826 Negative_regulation of Protein_catabolism of HFE2 1 0.18 0.25 0.04 97.00
75 INT315563 Positive_regulation of Gene_expression of FXN 4 0.41 5.05 0 96.80
76 INT315551 Negative_regulation of Gene_expression of ALAS2 1 0.37 1.11 0 96.80
77 INT64461 Regulation of Gene_expression of Reg3b 2 0.61 1.42 0.16 96.56
78 INT315622 Protein_catabolism of FECH 1 0.77 0.49 0.07 96.36
79 INT282679 Localization of FECH 1 0.12 9.57 0.23 96.32
80 INT100821 Localization of Ros1 59 0.60 45.26 11.92 96.32
81 INT24735 Regulation of TF 10 0.44 5.55 0.65 96.24
82 INT179697 Regulation of CYP4F3 4 0.47 4.36 0.83 96.24
83 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 96.24
84 INT132453 Binding of TF 31 0.36 12.98 1.22 96.12
85 INT315576 Positive_regulation of Binding of CIAO1 1 0.22 0.67 0 96.08
86 INT315630 Gene_expression of FXN 8 0.64 20.05 0.05 95.84
87 INT670 Gene_expression of B2m 31 0.66 27.32 8.49 95.84
88 INT315589 Binding of CIAO1 1 0.16 0.67 0 95.56
89 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 95.52
90 INT315624 Positive_regulation of Gene_expression of ISCU 1 0.38 0.23 0.03 95.28
91 INT338794 Binding of TMPRSS6 1 0.36 0.33 0.04 94.96
92 INT199653 Positive_regulation of Tfrc 2 0.13 1.57 0 94.92
93 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57 94.92
94 INT73223 Gene_expression of UPF1 78 0.41 31.44 9.94 94.92
95 INT174848 Gene_expression of ISCU 2 0.59 2.79 0.08 94.80
96 INT238833 Negative_regulation of RBP4 1 0.42 2.41 0 94.72
97 INT3851 Gene_expression of Got1 58 0.65 29.15 10.52 94.68
98 INT310527 Gene_expression of MDFIC 1 0.05 1.87 0.29 94.64
99 INT228893 Binding of TFRC 4 0.16 2.81 0.03 94.56
100 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 94.56
101 INT252722 Binding of IREB2 2 0.16 1.31 0 94.52
102 INT315631 Protein_catabolism of IREB2 1 0.44 0.4 0 94.52
103 INT315632 Positive_regulation of Protein_catabolism of IREB2 1 0.22 0.4 0 94.52
104 INT3323 Gene_expression of ALAS2 10 0.58 7.51 0.21 94.44
105 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71 94.28
106 INT12915 Gene_expression of MGP 18 0.75 7.53 4.15 93.88
107 INT50530 Binding of MDFIC 2 0.17 1.88 0.38 93.76
108 INT12292 Negative_regulation of Positive_regulation of GH1 22 0.58 5.02 8.28 93.68
109 INT139366 Gene_expression of PROM1 98 0.77 67.84 3.39 93.56
110 INT94423 Binding of ALAS2 4 0.32 2.1 0.61 93.28
111 INT3321 Positive_regulation of ALAS2 10 0.51 3.08 0.32 93.28
112 INT204144 Negative_regulation of Localization of Slc40a1 1 0.03 0.99 0.11 93.24
113 INT65500 Gene_expression of App 605 0.78 429.94 98.31 93.16
114 INT120201 Gene_expression of Aco1 54 0.35 26.29 2.95 93.16
115 INT120202 Gene_expression of Ern1 2 0.14 1.78 0.21 93.16
116 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 93.08
117 INT921 Regulation of GH1 172 0.60 52.88 51.04 92.88
118 INT250 Regulation of GHRH 65 0.61 17.46 23.19 92.88
119 INT12042 Regulation of MIA3 28 0.23 17.33 5.79 92.88
120 INT18406 Regulation of Regulation of GHRH 2 0.45 0.93 0.76 92.88
121 INT23402 Binding of HLA-DOA 74 0.48 52.01 10.89 92.80
122 INT201091 Regulation of HLA-DOA 5 0.20 3.6 0.44 92.80
123 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71 92.76
124 INT69436 Negative_regulation of Gene_expression of ROS1 81 0.38 46.58 12.22 92.76
125 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 92.76
126 INT204146 Localization of Slc40a1 1 0.05 0.99 0.11 92.72
127 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 92.48
128 INT179698 Positive_regulation of CYP4F3 5 0.54 3.86 0.91 92.48
129 INT283402 Binding of Nt5e 10 0.30 2.53 0.85 92.32
130 INT283398 Negative_regulation of Binding of Nt5e 1 0.05 0.46 0 92.32
131 INT166958 Gene_expression of LYRM4 4 0.18 2.9 0.27 92.20
132 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 92.16
133 INT94784 Binding of ROS1 113 0.40 71.57 10.26 92.08
134 INT315588 Regulation of ACO1 1 0.18 0.57 0 91.84
135 INT338793 Transcription of TMPRSS6 1 0.69 0.46 0.07 91.80
136 INT315552 Negative_regulation of GLRX5 1 0.38 2.17 0 91.40
137 INT74870 Gene_expression of Apo 17 0.75 12.5 1.38 91.24
138 INT315566 Negative_regulation of Binding of ABCB7 1 0.37 0.62 0 91.20
139 INT7083 Positive_regulation of HBM 35 0.66 20.96 4.3 91.16
140 INT4391 Gene_expression of SERPINA1 47 0.78 41.43 9.7 90.88
141 INT29833 Binding of Spna1 39 0.27 19.4 1.74 90.88
142 INT294982 Regulation of Localization of CYBB 1 0.07 1.22 0 90.56
143 INT48888 Localization of Pbrgcsf1 11 0.29 5.04 2.05 90.44
144 INT258918 Negative_regulation of Gene_expression of HLA-DRB3 1 0.22 1.52 0.13 90.40
145 INT239896 Positive_regulation of Gene_expression of Hfe 1 0.13 0.65 0 90.40
146 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 90.12
147 INT315605 Binding of ABCB7 1 0.33 1.84 0 90.00
148 INT205995 Gene_expression of SLC7A7 11 0.75 10.61 1.21 89.92
149 INT12194 Gene_expression of Trf 38 0.69 18.1 4.56 89.84
150 INT45236 Positive_regulation of Gene_expression of Trf 3 0.62 1.67 0.28 89.84
151 INT17033 Positive_regulation of Trf 21 0.62 11.76 2.68 89.48
152 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 89.44
153 INT310523 Localization of MDFIC 1 0.05 0.83 0.14 89.44
154 INT315600 Regulation of CIAO1 1 0.20 0.39 0 89.44
155 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 89.28
156 INT327506 Localization of IGKV1-16 1 0.05 0.52 0 89.20
157 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 89.12
158 INT56098 Gene_expression of HLA-DRB3 5 0.59 2.89 0.99 89.04
159 INT315616 Positive_regulation of Gene_expression of ACO1 1 0.20 0.79 0 88.96
160 INT176892 Binding of MR1 36 0.32 15.55 2.58 88.80
161 INT315623 Positive_regulation of Localization of ACO1 1 0.20 0.79 0 88.48
162 INT315574 Localization of ACO1 1 0.30 0.79 0 88.48
163 INT249 Localization of GHRH 215 0.80 78.02 51.87 88.44
164 INT984 Positive_regulation of Localization of GHRH 58 0.70 12.66 16.51 88.44
165 INT42176 Gene_expression of DFP 2 0.39 3.71 1.03 88.20
166 INT79140 Binding of HCC 36 0.31 46.96 1.87 88.12
167 INT241860 Positive_regulation of Transcription of EPO 3 0.55 4 0 87.88
168 INT243267 Positive_regulation of SLC40A1 4 0.41 2.72 0.22 87.80
169 INT1644 Regulation of FSHR 77 0.55 15.62 21.49 87.68
170 INT25047 Positive_regulation of Regulation of FSHR 3 0.31 0.92 0.29 87.68
171 INT222311 Gene_expression of IGKV1-16 4 0.15 4.64 0.3 87.44
172 INT315591 Negative_regulation of Positive_regulation of SLC40A1 1 0.25 0.46 0 87.28
173 INT106020 Transcription of EPO 8 0.71 9.34 0.6 87.20
174 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 87.12
175 INT315580 Negative_regulation of Localization of SLC40A1 1 0.25 0.64 0 87.08
176 INT296387 Localization of SLC40A1 2 0.44 0.94 0 87.08
177 INT199875 Localization of CYBB 16 0.72 5.77 0.62 87.00
178 INT315558 Negative_regulation of SLC40A1 1 0.25 0.63 0 86.56
179 INT138696 Positive_regulation of Ccl2 57 0.67 59.57 19.58 86.52
180 INT47041 Regulation of Apo 8 0.44 11.13 0.94 86.48
181 INT15310 Gene_expression of DLEU1 8 0.67 20.57 0.96 86.40
182 INT315626 Localization of DLEU1 2 0.35 4.17 0.07 86.40
183 INT6516 Positive_regulation of BGLAP 45 0.67 26.61 9.9 86.40
184 INT288681 Regulation of Transcription of Slc11a2 1 0.44 0.37 0.13 86.08
185 INT288683 Transcription of Slc11a2 1 0.69 0.37 0.13 85.48
186 INT142735 Regulation of RLS 33 0.53 45.83 11.35 85.04
187 INT162471 Positive_regulation of ERN1 7 0.34 3.02 1.08 84.92
188 INT102698 Binding of ACCS 54 0.42 66.73 9.06 84.88
189 INT315549 Negative_regulation of Binding of WNT2 1 0.08 0.65 0 84.52
190 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 84.28
191 INT80657 Gene_expression of SLC17A5 50 0.75 39.98 5.44 84.28
192 INT114311 Negative_regulation of Gene_expression of Gpt 33 0.38 17.83 4.94 84.28
193 INT315579 Binding of WNT2 1 0.07 0.65 0 84.08
194 INT197014 Localization of LDLR 8 0.63 3.29 0.03 84.04
195 INT164957 Regulation of Gene_expression of Hras1 8 0.04 4.4 0.64 83.92
196 INT164958 Regulation of Gene_expression of HBB 1 0.44 0.59 0.07 83.92
197 INT11650 Negative_regulation of Gpt 122 0.59 69.15 30.36 83.88
198 INT315597 Negative_regulation of ISCU 1 0.51 0.22 0 83.60
199 INT315553 Positive_regulation of GLRX5 1 0.44 0.68 0 83.60
200 INT128793 Gene_expression of HBB 16 0.78 10.69 0.42 83.56
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox