D:Junctional Epidermolysis Bullosa

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Disease Term
Synonyms EPIDERMOLYSIS BULLOSA LETALIS, Epidermolysis Bullosa Progressiva, Herlitz Disease, Herlitz S Disease, LETHAL JUNCTIONAL EPIDERMOLYSIS BULLOSA
Documents 9
Hot Single Events 7
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Junctional Epidermolysis Bullosa. They are ordered first by their relevance to Junctional Epidermolysis Bullosa and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT236467 MMP9 Negative_regulation of SNRPB 1 0.01 0.45 0.1 97.44
2 INT236466 SNRPB Positive_regulation of NFKB2 1 0.00 0.21 0.05 5.00
3 INT236468 TP53 Positive_regulation of Protein_catabolism of SNRPB 1 0.00 0.52 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Junctional Epidermolysis Bullosa. They are ordered first by their pain relevance and then by number of times they were reported in Junctional Epidermolysis Bullosa. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT236475 Localization of SNRPB 1 0.04 2.85 0.13 98.80
2 INT106806 Negative_regulation of Binding of Lama5 1 0.09 1.03 0.09 98.76
3 INT106807 Binding of Lama5 2 0.08 1.71 0.24 98.76
4 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42 98.20
5 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 97.96
6 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 96.68
7 INT39414 Gene_expression of SNRPB 37 0.59 14.07 2.52 81.80
8 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02 75.16
9 INT82066 Gene_expression of COL17A1 1 0.74 1.83 0.3 75.00
10 INT82067 Positive_regulation of Gene_expression of COL17A1 1 0.66 0.91 0.15 75.00
11 INT82068 Negative_regulation of Gene_expression of COL17A1 1 0.41 0.41 0.07 75.00
12 INT236480 Positive_regulation of Gene_expression of SNRPB 2 0.13 0.79 0.1 72.00
13 INT168304 Positive_regulation of SNRPB 17 0.25 9.62 1.64 71.04
14 INT155929 Positive_regulation of Negative_regulation of PARP1 2 0.49 1.02 0.04 16.56
15 INT236481 Negative_regulation of Negative_regulation of PARP1 1 0.15 0.95 0.04 13.76
16 INT99348 Negative_regulation of PARP1 38 0.58 30.96 3.36 12.80
17 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
18 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 5.00
19 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 5.00
20 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 5.00
21 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71 5.00
22 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 5.00
23 INT48235 Negative_regulation of NPEPPS 72 0.46 44.54 25.03 5.00
24 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48 5.00
25 INT113845 Protein_catabolism of PARP1 54 0.88 43.86 8.77 5.00
26 INT76091 Positive_regulation of NOS3 48 0.61 18.4 7.92 5.00
27 INT126583 Positive_regulation of PARP1 50 0.68 41.44 7.78 5.00
28 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93 5.00
29 INT91463 Positive_regulation of NFKB2 19 0.40 17.7 4.6 5.00
30 INT39413 Negative_regulation of SNRPB 7 0.31 2.57 2.36 5.00
31 INT70860 Binding of SNRPB 17 0.35 7 1.46 5.00
32 INT45155 Negative_regulation of Polymerase 18 0.51 15.18 1.38 5.00
33 INT92455 Transcription of SNRPB 3 0.52 1.21 1.27 5.00
34 INT107922 Positive_regulation of Gene_expression of NOS3 17 0.60 9.32 1.04 5.00
35 INT211808 Localization of NFKB2 4 0.19 4.17 0.58 5.00
36 INT39412 Negative_regulation of Gene_expression of SNRPB 2 0.14 0.95 0.27 5.00
37 INT189970 Positive_regulation of Positive_regulation of SNRPB 1 0.22 1.69 0.08 5.00
38 INT188001 Phosphorylation of H2afx 10 0.80 5.6 0.04 5.00
39 INT236476 Protein_catabolism of SNRPB 1 0.04 0.64 0 5.00
40 INT236477 Regulation of Binding of SNRPB 1 0.02 0.1 0 5.00
41 INT236479 Positive_regulation of Localization of SNRPB 1 0.03 1.39 0 5.00
42 INT236482 Regulation of Localization of SNRPB 1 0.01 0.17 0 5.00
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