D:Juvenile Chronic Polyarthritis

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Disease Term
Synonyms ARTHRITIDES JUVENILE IDIOPATHIC, Arthritis Juvenile Chronic, Arthritis Juvenile Idiopathic, Arthritis Juvenile Rheumatoid, Chronic Arthritis Juvenile, Idiopathic Arthritides Juvenile, Idiopathic Arthritis Juvenile, Juvenile Chronic Arthritis, Juvenile Chronic Polyarthritis Disorder, JUVENILE IDIOPATHIC ARTHRITIDES, Juvenile Idiopathic Arthritis
Documents 558
Hot Single Events 200
Hot Interactions 42

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Juvenile Chronic Polyarthritis. They are ordered first by their relevance to Juvenile Chronic Polyarthritis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT329962 Binding of C5 and HEPACAM 1 0.03 2.25 1.06 100.00
2 INT329959 Binding of TRAF1 and HEPACAM 1 0.03 2.25 1.06 100.00
3 INT329957 Binding of STAT4 and HEPACAM 1 0.03 1.41 0.7 100.00
4 INT107965 Binding of HLA-B and Mefv 2 0.34 3.91 1.61 100.00
5 INT340437 Binding of SERPINH1 and HLA-DRB4 1 0.00 2.26 0.84 99.84
6 INT230019 Binding of HLA-B and ERAL1 1 0.00 2.23 1.1 99.80
7 INT329954 Binding of PRKCQ and SNRNP70 1 0.07 0.65 0.33 99.76
8 INT329958 Binding of C5 and STAT4 1 0.33 0.93 0.41 99.54
9 INT329955 Binding of STAT4 and TRAF1 1 0.38 0.93 0.4 99.54
10 INT350144 Binding of LPP and NAA25 1 0.25 1.83 0.55 99.48
11 INT340439 Binding of HLA-DMA and SUGT1 1 0.00 4.1 1.16 99.36
12 INT340438 Binding of HLA-DMA and MRAP 1 0.02 1.69 0.43 99.36
13 INT350152 Binding of ATXN2 and SNRNP70 1 0.13 1.22 0.2 99.28
14 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66 99.20
15 INT350147 Binding of LPP and SH2B3 1 0.36 1.82 0.55 99.12
16 INT321598 Binding of MLL and TNF 1 0.05 1.07 0.49 99.06
17 INT350151 Binding of SNRNP70 and SH2B3 1 0.13 1.22 0.2 99.04
18 INT350150 Binding of LPP and ATXN2 1 0.35 1.82 0.54 98.88
19 INT329961 Binding of IL2RA and PTPN22 1 0.35 1.87 0.63 98.86
20 INT350148 Binding of IL12A and ERAL1 1 0.21 8.23 2.26 98.28
21 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42 98.16
22 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72 97.36
23 INT266391 Binding of Ager and S100a1 1 0.01 5.63 1.69 96.56
24 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 96.28
25 INT203103 ACAN Negative_regulation of Gene_expression of IL10 1 0.02 1.31 1.12 94.92
26 INT203105 MMP3 Negative_regulation of Gene_expression of IL10 1 0.06 0.69 0.56 94.56
27 INT173947 Il6 Positive_regulation of Gene_expression of IGF1 1 0.05 1.02 0.31 93.92
28 INT126555 Binding of Ighg1 and Tnf 1 0.35 2.2 0.8 93.28
29 INT329960 Binding of C5 and TRAF1 1 0.32 1.04 0.42 91.92
30 INT271874 IL10 Negative_regulation of TNF 1 0.07 0.78 0.5 90.60
31 INT350146 Binding of IL12A and RS1 1 0.01 0.97 0.23 90.12
32 INT329956 Binding of IL2 and IL23R 1 0.33 4.58 1.21 89.92
33 INT329963 Binding of IL21 and IL23R 1 0.30 2.28 0.6 89.92
34 INT173949 Binding of IGF1 and Atp6v1e1 1 0.01 0.89 0.28 86.96
35 INT271873 IL10 Regulation of Gene_expression of IK 1 0.00 0.81 0.47 85.24
36 INT271872 IL10 Regulation of IK 1 0.00 0.81 0.47 85.24
37 INT203104 MMP3 Positive_regulation of Gene_expression of IFN1@ 1 0.25 0.33 0.48 84.72
38 INT224580 Gene_expression of IL18 Positive_regulation of SERPINH1 1 0.00 1.34 0.7 84.72
39 INT224583 CSF2 Positive_regulation of IL1RN 1 0.02 1.3 0.88 84.48
40 INT224585 IL1B Positive_regulation of IL1RN 1 0.02 1.3 0.87 84.48
41 INT300855 Il1 Regulation of Il6 1 0.01 0.81 0.3 81.92
42 INT350145 Binding of SNRNP70 and ERAL1 1 0.05 1.29 0.28 81.24
43 INT350149 SH2B3 Regulation of CD8A 1 0.13 0.86 0.17 79.04
44 INT320153 Negative_regulation of Binding of IL6 and IL6R 1 0.02 0.37 0.24 78.44
45 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 77.72
46 INT340440 Binding of HLA-B and BTG3 1 0.05 1.57 0.47 75.84
47 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 75.16
48 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21 75.16
49 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 75.04
50 INT184164 Binding of PRSS1 and SAA@ 1 0.02 0.39 0.07 74.52
51 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 74.24
52 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 73.84
53 INT202043 MMP13 Regulation of Protein_catabolism of COL2A1 1 0.01 0.54 0.54 64.40
54 INT338941 Binding of Ggh and Mtx1 1 0.30 0.47 0.27 63.60
55 INT317832 Binding of Mefv and Il1 1 0.03 3.89 0.7 60.40
56 INT317834 Binding of Pstpip1 and Il1 1 0.00 2.03 0.48 60.40
57 INT278379 Binding of Pstpip1 and Mefv 3 0.03 2.02 0.48 58.88
58 INT178574 IL2RA Positive_regulation of Gene_expression of Cd3e 1 0.04 0.16 0.05 52.52
59 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41 51.76
60 INT266386 Binding of S100a1 and Trp53 1 0.03 0.64 0.1 51.04
61 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85 50.88
62 INT285467 Negative_regulation of Binding of IL1B and IL1RN 1 0.05 1.33 0.61 50.88
63 INT338940 Fpgs Positive_regulation of Mtx1 1 0.32 0.32 0.47 50.00
64 INT188432 Negative_regulation of Binding of ABCA1 and IL6 1 0.02 0.47 0.05 50.00
65 INT188431 Binding of ABCA1 and IL6 1 0.02 0.47 0.05 50.00
66 INT173948 Gh Positive_regulation of Gene_expression of IGF1 2 0.36 0.77 0.1 46.80
67 INT317833 Nlrp3 Positive_regulation of Localization of Il1 1 0.06 1.38 0.26 45.76
68 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 44.24
69 INT202038 MMP9 Positive_regulation of IL8 1 0.05 0.29 0.59 41.16
70 INT306925 IL36RN Positive_regulation of HAMP 1 0.01 1.39 0.1 35.00
71 INT306924 IL6 Positive_regulation of HAMP 1 0.02 1.38 0.1 35.00
72 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24 26.32
73 INT173937 Hrt1 Regulation of Il1 1 0.00 0.28 0.13 15.96
74 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 10.32
75 INT306936 Binding of Tnfsf12 and Tnfrsf12a 1 0.05 4.84 0.45 9.28
76 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 5.92
77 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48 5.00
78 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76 5.00
79 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14 5.00
80 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95 5.00
81 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95 5.00
82 INT282398 Binding of Mefv and Nlrp3 1 0.40 6.8 1.72 5.00
83 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57 5.00
84 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55 5.00
85 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46 5.00
86 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36 5.00
87 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32 5.00
88 INT300864 Ngf Positive_regulation of Mapk14 2 0.60 1.38 1.32 5.00
89 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3 5.00
90 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27 5.00
91 INT202042 CAMK2N2 Negative_regulation of MMP9 1 0.01 0.73 1.25 5.00
92 INT202041 CAMK2N2 Negative_regulation of PPP1R11 1 0.00 0.74 1.25 5.00
93 INT202039 CAMK2N2 Negative_regulation of MMP1 1 0.00 0.73 1.24 5.00
94 INT202036 CAMK2N2 Negative_regulation of MMP3 1 0.00 0.73 1.24 5.00
95 INT202040 CAMK2N2 Negative_regulation of MMP7 1 0.00 0.73 1.24 5.00
96 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07 5.00
97 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 5.00
98 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01 5.00
99 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 5.00
100 INT317836 Binding of Fibp and Pycard 1 0.00 2.68 0.98 5.00
101 INT132610 Bdnf Positive_regulation of Ntrk2 4 0.46 1.09 0.93 5.00
102 INT285561 Il23a Positive_regulation of Gene_expression of Il22 2 0.06 2.45 0.93 5.00
103 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93 5.00
104 INT302828 Mapkapk5 Positive_regulation of Mapk1 1 0.07 1.38 0.91 5.00
105 INT343918 IgG Positive_regulation of Phosphorylation of MAPK1 1 0.01 3.57 0.91 5.00
106 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91 5.00
107 INT343834 Binding of CD14 and IRF6 1 0.02 2.08 0.9 5.00
108 INT343847 IRF6 Positive_regulation of TBCE 1 0.01 1.11 0.87 5.00
109 INT343829 TLR1 Positive_regulation of TBCE 1 0.03 0.96 0.85 5.00
110 INT262572 Ngf Positive_regulation of Mapk1 2 0.04 0.52 0.81 5.00
111 INT302831 Binding of Creb1 and Mapkapk5 1 0.07 1.3 0.79 5.00
112 INT239064 Binding of Mbl1 and IgG 1 0.03 2.59 0.78 5.00
113 INT266408 Binding of HMGB1 and Ager 1 0.01 2.57 0.76 5.00
114 INT248271 IL6 Regulation of Gene_expression of Crp 3 0.27 1.7 0.73 5.00
115 INT172134 Binding of IL6 and IL15 2 0.01 1.18 0.72 5.00
116 INT172147 Binding of IL15 and TNF 2 0.05 1.19 0.72 5.00
117 INT139069 Binding of CTLA4 and Cd86 3 0.16 0.65 0.7 5.00
118 INT172143 IL4 Positive_regulation of Protein_catabolism of TNF 2 0.11 1.7 0.69 5.00
119 INT172146 IL10 Positive_regulation of Protein_catabolism of TNF 2 0.15 1.69 0.69 5.00
120 INT172142 IL10 Positive_regulation of Protein_catabolism of IL1B 2 0.03 1.69 0.68 5.00
121 INT172132 IL4 Positive_regulation of Protein_catabolism of IL1B 2 0.02 1.69 0.68 5.00
122 INT202037 Binding of CRP and URB1 1 0.01 1.26 0.68 5.00
123 INT285562 Binding of Il27ra and Il27 1 0.10 2.19 0.67 5.00
124 INT203758 Binding of IL6 and TNF 3 0.26 2.03 0.67 5.00
125 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66 5.00
126 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63 5.00
127 INT181084 Binding of S100a8 and S100a9 6 0.42 2.91 0.62 5.00
128 INT302833 Gene_expression of Mir155 Negative_regulation of Gene_expression of Mmp3 1 0.03 1 0.57 5.00
129 INT333476 IL12B Positive_regulation of Localization of AFP 1 0.03 0.26 0.57 5.00
130 INT333477 CXCL10 Positive_regulation of TH1L 1 0.14 0.32 0.56 5.00
131 INT302832 Tnfsf10 Positive_regulation of Akt1 1 0.04 1.63 0.56 5.00
132 INT306935 Tnfsf12 Positive_regulation of Gene_expression of Cxcl10 1 0.03 3.55 0.55 5.00
133 INT266381 Positive_regulation of Ager Positive_regulation of Nfkb1 1 0.00 0.77 0.55 5.00
134 INT176340 CHI3L1 Positive_regulation of Localization of CSF2 1 0.11 1.86 0.55 5.00
135 INT176343 CHI3L1 Positive_regulation of Localization of CSF1 1 0.23 1.86 0.55 5.00
136 INT316736 Il1 Positive_regulation of Timp1 1 0.04 0.63 0.54 5.00
137 INT266376 Binding of Ager and Itgam 1 0.00 2.31 0.54 5.00
138 INT176342 CSF1 Positive_regulation of Localization of CSF2 1 0.26 1.84 0.54 5.00
139 INT302834 Cd4 Positive_regulation of Gene_expression of Il7 1 0.05 1.02 0.54 5.00
140 INT316737 Il1 Positive_regulation of Mmp1a 1 0.01 0.64 0.54 5.00
141 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54 5.00
142 INT316738 Il1 Positive_regulation of Mmp3 1 0.02 0.63 0.54 5.00
143 INT316735 Il1 Positive_regulation of Gene_expression of Il1rn 1 0.00 0.53 0.53 5.00
144 INT343838 EDA Positive_regulation of TLR4 1 0.11 0.87 0.51 5.00
145 INT343859 Binding of IRF6 and TBCE 1 0.01 1.1 0.51 5.00
146 INT343860 Binding of CD14 and TBCE 1 0.03 1.1 0.51 5.00
147 INT172081 TNF Regulation of IFNA1 1 0.03 1.13 0.5 5.00
148 INT343825 IRF6 Regulation of Gene_expression of FUT1 1 0.00 1.74 0.5 5.00
149 INT302838 TNF Positive_regulation of Sox18 1 0.00 0.71 0.5 5.00
150 INT302845 Il7 Positive_regulation of Gene_expression of TNF 1 0.01 0.98 0.49 5.00
151 INT302820 Stat3 Regulation of Positive_regulation of Il7 1 0.04 1.03 0.49 5.00
152 INT302823 Stat3 Regulation of Gene_expression of Il7 1 0.04 1.03 0.49 5.00
153 INT300551 TBX21 Regulation of Hand1 2 0.10 0.44 0.48 5.00
154 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47 5.00
155 INT300544 Il22 Positive_regulation of Gene_expression of Mcpt1 1 0.02 1.15 0.47 5.00
156 INT150393 Binding of CASP1 and MEFV 2 0.16 2.48 0.45 5.00
157 INT173936 Hrt1 Regulation of Gtf3a 1 0.00 1.16 0.44 5.00
158 INT343846 MAPK1 Positive_regulation of FOS 1 0.04 1.29 0.44 5.00
159 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43 5.00
160 INT343853 IRF6 Positive_regulation of PECAM1 1 0.00 0.53 0.43 5.00
161 INT299041 SPARC Regulation of Gene_expression of NPEPPS 1 0.01 0.83 0.42 5.00
162 INT299040 Binding of COL7A1 and SPARC 1 0.02 0.7 0.42 5.00
163 INT346130 Il17a Positive_regulation of Gene_expression of TNFSF11 1 0.08 0.61 0.41 5.00
164 INT343916 Hspa1a Positive_regulation of Gene_expression of TNF 1 0.16 1.17 0.41 5.00
165 INT343919 Hspa1a Positive_regulation of Gene_expression of IL6 1 0.02 1.17 0.4 5.00
166 INT343907 Hspa1a Positive_regulation of Gene_expression of Cxcl2 1 0.01 1.17 0.4 5.00
167 INT302824 Mapkapk5 Positive_regulation of Phosphorylation of Hspb2 1 0.11 0.64 0.4 5.00
168 INT343844 Binding of IRF6 and LY96 1 0.01 1.03 0.4 5.00
169 INT266393 Binding of Ager and Fn1 1 0.00 0.82 0.39 5.00
170 INT266382 Binding of Col4a1 and Fn1 1 0.00 0.82 0.39 5.00
171 INT302825 Binding of Creb1 and Xpnpep1 1 0.00 0.64 0.39 5.00
172 INT295478 IRF6 Positive_regulation of Positive_regulation of TLR4 2 0.20 0.78 0.39 5.00
173 INT285560 Il23a Positive_regulation of Il17a 1 0.09 1.45 0.39 5.00
174 INT329799 Binding of CD14 and LY96 2 0.04 1.02 0.39 5.00
175 INT300547 Il6 Positive_regulation of Il21 1 0.02 0.78 0.39 5.00
176 INT302836 Negative_regulation of Mapk8 Negative_regulation of TNF Positive_regulation of Mir155 1 0.00 0.48 0.39 5.00
177 INT282397 Binding of Irgm1 and Atg16l1 1 0.17 1.18 0.39 5.00
178 INT285571 Binding of IL8 and Il17a 1 0.04 1.03 0.38 5.00
179 INT266397 Binding of Ager and Col4a1 1 0.00 0.81 0.38 5.00
180 INT302815 TNF Positive_regulation of TNF Positive_regulation of Mir155 1 0.00 0.47 0.38 5.00
181 INT302840 Positive_regulation of TNF Positive_regulation of Mir155 1 0.01 0.47 0.38 5.00
182 INT302821 Mdk Negative_regulation of Il1 1 0.02 0.91 0.38 5.00
183 INT302843 TNF Positive_regulation of Mir155 1 0.01 0.47 0.38 5.00
184 INT266419 HMGB1 Positive_regulation of Ager 1 0.01 1.37 0.37 5.00
185 INT224582 Binding of IL1B and Positive_regulation of Gene_expression of TNF 1 0.05 1.33 0.37 5.00
186 INT224584 Binding of IL1RN and SIGMAR1 1 0.00 0.73 0.36 5.00
187 INT285568 Binding of TNF and Tnfsf10 1 0.12 1.39 0.36 5.00
188 INT285557 Eae2 Positive_regulation of Cia1 1 0.02 1.85 0.36 5.00
189 INT285465 IL7 Positive_regulation of TNF 1 0.04 0.67 0.35 5.00
190 INT343912 Fgg Positive_regulation of Gene_expression of IL6 1 0.00 0.83 0.35 5.00
191 INT266402 Binding of S100P and Ager 1 0.00 2.25 0.35 5.00
192 INT343857 Binding of ABCC8 and LY96 1 0.02 0.96 0.34 5.00
193 INT285570 Binding of IL8 and Cdkn1c 1 0.11 0.76 0.34 5.00
194 INT188391 Binding of CD4 and HLA-DRB1 1 0.05 0.96 0.34 5.00
195 INT285565 Positive_regulation of Zeb1 Negative_regulation of IL2 1 0.02 0.62 0.33 5.00
196 INT285558 Binding of Il11ra1 and Il27 1 0.05 1.1 0.33 5.00
197 INT285566 F8 Negative_regulation of IL2 1 0.00 0.62 0.33 5.00
198 INT266383 Binding of Ager and S100b 1 0.01 3.48 0.33 5.00
199 INT302830 Mapk14 Regulation of Mapkapk5 1 0.12 0.53 0.33 5.00
200 INT285563 Zeb1 Negative_regulation of IL2 1 0.01 0.62 0.33 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Juvenile Chronic Polyarthritis. They are ordered first by their pain relevance and then by number of times they were reported in Juvenile Chronic Polyarthritis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 100.00
2 INT88322 Gene_expression of CCR5 111 0.78 77.36 39.84 100.00
3 INT121663 Gene_expression of CXCR3 76 0.77 50.96 30.62 100.00
4 INT2249 Negative_regulation of Binding of HLA-B 5 0.54 6.82 2.94 100.00
5 INT182224 Binding of CCL21 6 0.34 5.91 2.54 100.00
6 INT250699 Binding of CDK6 3 0.33 2.54 0.97 100.00
7 INT162557 Binding of MMEL1 2 0.32 3.13 1.03 100.00
8 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 100.00
9 INT1499 Negative_regulation of Gene_expression of Gh 58 0.42 25.17 7.86 99.98
10 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.96
11 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.96
12 INT24232 Localization of Mtx1 24 0.65 8.06 7.99 99.96
13 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 99.92
14 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 99.92
15 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 99.92
16 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 99.92
17 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 99.92
18 INT260118 Regulation of Regulation of CD4 1 0.44 1.66 0.4 99.92
19 INT33567 Gene_expression of CALM1 139 0.67 48.85 56.14 99.90
20 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.86
21 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 99.84
22 INT71680 Gene_expression of CCL3 43 0.75 33.7 18.01 99.84
23 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74 99.84
24 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 99.84
25 INT16404 Regulation of CD4 54 0.61 33.05 10.29 99.84
26 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 99.84
27 INT209750 Positive_regulation of CLLU1 1 0.02 0.6 0.16 99.84
28 INT137181 Gene_expression of CXCL9 25 0.65 13.09 9.56 99.84
29 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 99.84
30 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63 99.84
31 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 99.80
32 INT145594 Gene_expression of Mtx1 64 0.57 35.33 30.35 99.80
33 INT220219 Binding of HUNK 1 0.26 12.47 3.78 99.80
34 INT293158 Gene_expression of TRAF1 2 0.63 3.62 1.81 99.80
35 INT64147 Gene_expression of C5 15 0.60 16.8 2.78 99.80
36 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 99.76
37 INT169180 Binding of SNRNP70 204 0.47 119.1 29.3 99.76
38 INT5788 Gene_expression of IL2RA 60 0.75 40.67 9.98 99.76
39 INT11747 Positive_regulation of IL2RA 22 0.67 16.55 6.95 99.76
40 INT25163 Positive_regulation of Gene_expression of IL2RA 8 0.45 5.37 1.71 99.76
41 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 99.76
42 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 99.70
43 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86 99.68
44 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 99.68
45 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78 99.64
46 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 99.62
47 INT157357 Binding of IL2RA 6 0.44 5.18 1.63 99.60
48 INT146300 Binding of RS1 31 0.22 29.55 3.04 99.58
49 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 99.56
50 INT45976 Positive_regulation of SAA@ 2 0.67 2.26 0.4 99.56
51 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09 99.54
52 INT165773 Gene_expression of Darc 37 0.75 22.28 14.84 99.52
53 INT107242 Binding of MMP3 14 0.47 12.06 5.11 99.52
54 INT6507 Binding of C5 23 0.48 15.35 3.91 99.52
55 INT102987 Regulation of MMP3 23 0.60 9.35 9.54 99.52
56 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 99.52
57 INT79477 Binding of HLA-DMA 19 0.26 13.78 3.47 99.48
58 INT73499 Positive_regulation of IL13 23 0.39 20.03 6.53 99.48
59 INT350155 Binding of NAA25 1 0.23 1.8 0.54 99.48
60 INT7339 Localization of CALM1 46 0.75 16.15 16.47 99.48
61 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 99.46
62 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 99.40
63 INT329968 Binding of TRAF1 1 0.45 3.42 1.37 99.40
64 INT9210 Regulation of IL6 166 0.62 125.61 49.95 99.28
65 INT260110 Positive_regulation of Regulation of CD4 2 0.48 1.5 0.32 99.28
66 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89 99.28
67 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 99.24
68 INT81929 Negative_regulation of Gene_expression of IL10 41 0.57 27.99 9.87 99.20
69 INT24816 Binding of CD40LG 68 0.47 45.48 11.56 99.12
70 INT350153 Binding of SH2B3 1 0.34 4.41 1.19 99.12
71 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 99.08
72 INT239059 Binding of Mbl2 1 0.33 2.73 0.75 99.04
73 INT226443 Binding of STAT4 3 0.45 3.81 2.06 98.96
74 INT83451 Positive_regulation of Gene_expression of CD40LG 26 0.60 22.81 6.25 98.88
75 INT350157 Binding of ATXN2 1 0.33 3.53 1.02 98.88
76 INT3545 Positive_regulation of Mtx1 27 0.42 11.97 14.83 98.88
77 INT186506 Negative_regulation of BTG3 4 0.41 3.31 0.36 98.88
78 INT89293 Positive_regulation of Gene_expression of CCR5 29 0.70 22.14 15 98.88
79 INT231573 Binding of PTPN22 5 0.44 7.94 2.33 98.86
80 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 98.84
81 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 98.76
82 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 98.76
83 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 98.76
84 INT6852 Localization of TNF 883 0.81 705.95 270.84 98.72
85 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 98.72
86 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51 98.70
87 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 98.68
88 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98 98.68
89 INT78898 Regulation of Gene_expression of CCL5 9 0.42 5.7 3.11 98.64
90 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 98.64
91 INT89292 Positive_regulation of CCR5 27 0.70 15.12 8.59 98.62
92 INT171742 Positive_regulation of CXCR3 17 0.58 12.26 7.72 98.62
93 INT137400 Regulation of Mtx1 16 0.52 9.19 9.45 98.60
94 INT169015 Gene_expression of FOXP3 50 0.60 33.18 8.4 98.56
95 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95 98.52
96 INT48725 Gene_expression of IGFBP3 128 0.78 78.83 8.19 98.50
97 INT53143 Localization of FRTS 7 0.64 1.77 0.68 98.44
98 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 98.36
99 INT203116 Positive_regulation of ACAN 6 0.67 3.98 1.56 98.36
100 INT121370 Positive_regulation of MIF 22 0.70 17.79 6.08 98.36
101 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 98.36
102 INT137180 Binding of CXCR3 10 0.41 4.24 3.53 98.36
103 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 98.28
104 INT28300 Gene_expression of GHR 10 0.78 4.29 1.5 98.26
105 INT184168 Localization of GHR 1 0.08 0.34 0.05 98.26
106 INT1893 Localization of Gh 1041 0.79 340.23 256.58 98.24
107 INT51840 Positive_regulation of Localization of CD40LG 8 0.69 9.59 1.58 98.22
108 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 98.16
109 INT86437 Binding of IL6 154 0.48 121.22 29.3 98.16
110 INT6484 Binding of IL1B 122 0.47 75.84 35.07 98.16
111 INT92470 Negative_regulation of Gene_expression of CCL5 15 0.50 5.46 5.86 98.10
112 INT120014 Transcription of CCL3 5 0.69 3.03 1.82 98.08
113 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 98.04
114 INT95904 Gene_expression of CD27 45 0.76 26.17 1.93 98.00
115 INT117186 Positive_regulation of CXCR4 29 0.69 24.19 6.84 98.00
116 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72 98.00
117 INT103674 Positive_regulation of Gene_expression of CXCR4 32 0.69 37.1 3.08 98.00
118 INT120371 Gene_expression of FEZF2 12 0.66 4.97 1.38 97.98
119 INT171134 Gene_expression of CD28 67 0.65 32.55 13.61 97.96
120 INT10763 Localization of IL2 157 0.80 81.11 33.21 97.92
121 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 97.92
122 INT146758 Gene_expression of LCN2 45 0.78 38.29 2.97 97.88
123 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 97.84
124 INT157840 Regulation of Darc 4 0.02 2.35 1.47 97.84
125 INT220217 Transcription of HUNK 1 0.28 0.68 0.14 97.84
126 INT45753 Localization of CD40LG 45 0.79 32.31 5.28 97.82
127 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75 97.80
128 INT1530 Regulation of Gh 382 0.61 115.96 112.47 97.80
129 INT132161 Gene_expression of MTX1 48 0.58 26.55 32.32 97.76
130 INT184171 Localization of FEZF2 1 0.12 0.34 0.05 97.76
131 INT6481 Binding of TNF 624 0.48 510.2 214.82 97.68
132 INT165774 Transcription of Darc 2 0.01 2.95 2.23 97.68
133 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34 97.68
134 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 97.68
135 INT79693 Regulation of Il4 30 0.51 21.96 8.6 97.60
136 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 97.60
137 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45 97.56
138 INT67060 Negative_regulation of Transcription of TNF 17 0.59 12.94 5.88 97.52
139 INT64958 Negative_regulation of Transcription of IL6 6 0.50 3.58 0.92 97.52
140 INT221426 Positive_regulation of Gene_expression of FOXP3 9 0.48 5.98 1.72 97.50
141 INT78895 Regulation of CCL5 30 0.46 20.45 10.18 97.46
142 INT92234 Regulation of CXCL10 15 0.42 8.37 5.09 97.34
143 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 97.28
144 INT87495 Positive_regulation of Gene_expression of CCL5 26 0.69 13.85 9.46 97.20
145 INT71681 Positive_regulation of Gene_expression of CCL3 8 0.54 8.21 2.41 97.20
146 INT95898 Gene_expression of CAPG 14 0.39 10.51 2.33 97.20
147 INT266327 Negative_regulation of Binding of S100a1 1 0.16 1.23 0.33 97.20
148 INT4240 Positive_regulation of CCL5 32 0.58 20.55 10.65 97.16
149 INT133633 Positive_regulation of Darc 7 0.38 2.01 1.44 97.16
150 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 97.12
151 INT123828 Regulation of CCL3 3 0.60 0.79 1.25 97.12
152 INT260124 Positive_regulation of Positive_regulation of CCR5 1 0.14 0.84 0.51 97.12
153 INT220216 Gene_expression of HUNK 1 0.41 14.77 4.24 97.06
154 INT11699 Binding of HLA-E 85 0.47 52.51 13.41 97.00
155 INT184170 Binding of FEZF2 2 0.09 0.85 0.08 97.00
156 INT13354 Transcription of TNF 108 0.72 85.81 42.32 97.00
157 INT97513 Localization of Mefv 6 0.71 8.14 1.55 97.00
158 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 96.96
159 INT194658 Positive_regulation of Transcription of CCL5 1 0.45 0.68 0.44 96.96
160 INT64065 Gene_expression of Btg3 5 0.65 12.62 1.41 96.76
161 INT260116 Positive_regulation of CCR4 1 0.22 1.68 1.02 96.64
162 INT182233 Gene_expression of CCR4 14 0.43 6.55 3.31 96.64
163 INT260122 Positive_regulation of Gene_expression of CCR4 1 0.16 0.84 0.51 96.64
164 INT260125 Positive_regulation of Positive_regulation of CCR4 1 0.15 0.84 0.51 96.64
165 INT172076 Binding of DNAJB6 1 0.35 1.08 0.49 96.56
166 INT155153 Binding of S100a1 15 0.35 6.42 1.63 96.56
167 INT173878 Gene_expression of ACAN 32 0.75 9.35 3.55 96.48
168 INT50268 Gene_expression of FBN1 13 0.65 10.73 2.72 96.48
169 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 96.48
170 INT61626 Transcription of IL6 73 0.72 42.04 17.86 96.44
171 INT23174 Gene_expression of NLRP3 51 0.72 35.49 6.47 96.40
172 INT221427 Positive_regulation of FOXP3 6 0.45 2.74 0.83 96.36
173 INT11346 Binding of Mtx1 39 0.41 24.88 21.21 96.32
174 INT338935 Binding of Itpa 1 0.08 0.93 0.45 96.32
175 INT249457 Positive_regulation of URI1 3 0.27 0.8 0.45 96.24
176 INT103554 Positive_regulation of MTX1 19 0.45 11.23 10 96.16
177 INT103281 Transcription of CCL5 10 0.67 5.95 3.7 96.04
178 INT148207 Gene_expression of CTLA4 53 0.77 29.13 12.07 96.04
179 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 95.84
180 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03 95.84
181 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5 95.64
182 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 95.62
183 INT173852 Protein_catabolism of ACAN 3 0.64 1.65 1.01 95.60
184 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 95.56
185 INT8799 Negative_regulation of Csrp1 24 0.58 11.01 6.86 95.40
186 INT94337 Transcription of CXCL10 11 0.49 6.66 3.46 95.36
187 INT9656 Regulation of Gene_expression of Il6 57 0.62 33.3 17.71 95.32
188 INT169991 Regulation of SAA@ 1 0.26 2.63 0.73 95.20
189 INT340441 Positive_regulation of Binding of MTX1 1 0.17 1.7 0.72 94.80
190 INT350156 Positive_regulation of SH2B3 1 0.48 1.04 0.15 94.76
191 INT12194 Gene_expression of Trf 38 0.69 18.1 4.56 94.40
192 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 94.32
193 INT38276 Negative_regulation of CXCL10 10 0.42 9.26 3.19 94.24
194 INT115370 Gene_expression of PSIP1 22 0.65 9.45 5.68 94.16
195 INT15799 Positive_regulation of ISG20 18 0.38 9.78 2.01 94.04
196 INT260108 Positive_regulation of Il7r 3 0.49 2.83 0.43 94.04
197 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 94.00
198 INT169989 Gene_expression of SAA@ 5 0.65 4.05 0.96 94.00
199 INT183979 Localization of PSIP1 2 0.73 1.37 0.59 94.00
200 INT69985 Positive_regulation of Negative_regulation of TNF 21 0.50 13.26 6.31 93.96
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