D:Juvenile Myoclonic Epilepsy

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Disease Term
Synonyms Adolescent Myoclonic Epilepsies, Adolescent Myoclonic Epilepsy, Epilepsies Adolescent Myoclonic, Epilepsies Juvenile Myoclonic, Epilepsy Adolescent Myoclonic, Epilepsy Juvenile Myoclonic, Epilepsy Myoclonic Juvenile, Impulsive Petit Mal Epilepsy, Impulsive Petit Mal Janz, Janz Impulsive Petit Mal, Janz Juvenile Myoclonic Epilepsy
Documents 29
Hot Single Events 6
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Juvenile Myoclonic Epilepsy. They are ordered first by their relevance to Juvenile Myoclonic Epilepsy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT132442 Binding of RHAG and EFHC1 1 0.36 1.2 0.51 99.88
2 INT132443 Binding of MEP1A and EFHC1 1 0.44 1.19 0.5 99.88
3 INT264209 Binding of Igh-Lev and Sv2a 1 0.17 1.78 0.38 65.12
4 INT264210 Binding of Aes and Igh-Lev 1 0.07 0.41 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Juvenile Myoclonic Epilepsy. They are ordered first by their pain relevance and then by number of times they were reported in Juvenile Myoclonic Epilepsy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT267679 Negative_regulation of EJM2 1 0.04 1.15 0.14 100.00
2 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 91.76
3 INT167964 Gene_expression of Aes 30 0.58 25.41 10.16 90.00
4 INT158070 Localization of Aes 23 0.65 19.93 10.9 88.80
5 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 86.56
6 INT146355 Negative_regulation of Aes 15 0.51 7.83 4.25 83.44
7 INT311479 Gene_expression of Mllt1 4 0.58 4.92 2.39 77.04
8 INT264206 Gene_expression of Igh-Lev 1 0.30 5.68 0.87 72.48
9 INT264204 Regulation of Igh-Lev 1 0.20 3.17 0.1 66.16
10 INT129695 Binding of Sv2a 6 0.47 4.96 2.51 65.12
11 INT264207 Binding of Igh-Lev 1 0.25 4.13 1.07 64.48
12 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 62.96
13 INT92777 Positive_regulation of Gene_expression of ABAT 13 0.44 7.49 9.27 62.96
14 INT21131 Negative_regulation of Gene_expression of ABAT 6 0.42 4.93 2.83 62.96
15 INT258081 Protein_catabolism of ABAT 5 0.10 2.57 2.86 58.72
16 INT258051 Negative_regulation of Protein_catabolism of ABAT 3 0.04 1.86 1.52 58.72
17 INT6417 Negative_regulation of ABAT 49 0.51 19.6 36.81 58.72
18 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 55.16
19 INT177831 Gene_expression of HDAC1 24 0.65 21.37 8.37 49.60
20 INT34952 Regulation of ABAT 28 0.61 6.05 14.39 47.52
21 INT11934 Regulation of Sv2a 4 0.44 1.72 1.1 40.88
22 INT328545 Binding of Hdac9 1 0.11 0.09 0 33.68
23 INT263678 Negative_regulation of Igh-Lev 2 0.19 0.81 0.58 33.16
24 INT128563 Binding of Mllt1 8 0.41 6.7 5.63 31.48
25 INT192225 Gene_expression of HDAC9 35 0.58 32.82 6.36 29.48
26 INT133648 Regulation of HDAC9 14 0.60 10.01 2.18 29.48
27 INT291676 Regulation of Gene_expression of Dnmt1 2 0.26 0.57 0.04 13.68
28 INT90496 Gene_expression of Dnmt1 9 0.60 5.44 0.7 12.96
29 INT328534 Positive_regulation of Gene_expression of Dnmt1 1 0.10 0.07 0 12.96
30 INT146340 Localization of Mllt1 10 0.69 4.6 5.45 5.16
31 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
32 INT3439 Localization of Abat 1017 0.78 112.39 727.06 5.00
33 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
34 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43 5.00
35 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 5.00
36 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 5.00
37 INT4829 Positive_regulation of Localization of Abat 199 0.55 20.91 150.48 5.00
38 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 5.00
39 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 5.00
40 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
41 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
42 INT2212 Binding of Abat 89 0.48 18.36 63.99 5.00
43 INT122041 Binding of Ppara 308 0.48 189.17 51.48 5.00
44 INT12228 Positive_regulation of Gene_expression of Abat 44 0.65 17.51 40.55 5.00
45 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 5.00
46 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
47 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 5.00
48 INT17825 Gene_expression of Flvcr2 44 0.68 12.58 28.08 5.00
49 INT115385 Negative_regulation of Ppara 154 0.58 129.05 27.58 5.00
50 INT2912 Positive_regulation of Positive_regulation of Abat 29 0.66 6.48 27.54 5.00
51 INT63444 Regulation of Gene_expression of Abat 26 0.51 14.65 26.29 5.00
52 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6 5.00
53 INT31874 Negative_regulation of Gene_expression of Abat 31 0.42 12.22 20.31 5.00
54 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01 5.00
55 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 5.00
56 INT20420 Gene_expression of MYC 99 0.75 49.32 14.36 5.00
57 INT70265 Regulation of MRI1 42 0.39 30.95 14.18 5.00
58 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18 5.00
59 INT80790 Positive_regulation of Flvcr2 22 0.45 4.92 12.35 5.00
60 INT32203 Negative_regulation of Crp 48 0.58 32.77 11.89 5.00
61 INT19575 Negative_regulation of Positive_regulation of Abat 14 0.43 2.07 11.05 5.00
62 INT17824 Positive_regulation of Gene_expression of Flvcr2 15 0.41 6.66 10.23 5.00
63 INT53063 Positive_regulation of Slc1a1 10 0.70 3.23 9.89 5.00
64 INT62269 Gene_expression of Cdkn1a 60 0.73 35.78 9.84 5.00
65 INT158796 Positive_regulation of SMUG1 67 0.70 38.97 8.98 5.00
66 INT178174 Gene_expression of Tnfsf10 78 0.76 56.83 8.64 5.00
67 INT64815 Binding of Jun 49 0.48 21.47 8.59 5.00
68 INT80034 Positive_regulation of Gene_expression of FAS 32 0.67 30.34 8.51 5.00
69 INT114873 Phosphorylation of Stat3 63 0.82 30.19 8.23 5.00
70 INT150422 Positive_regulation of Aes 24 0.43 15.63 8 5.00
71 INT162393 Gene_expression of SMUG1 58 0.75 38.78 7.7 5.00
72 INT113 Positive_regulation of MBD2 33 0.49 6.76 7.49 5.00
73 INT264027 Positive_regulation of Positive_regulation of Flvcr2 2 0.08 2.67 7.27 5.00
74 INT111056 Negative_regulation of Gene_expression of Flvcr2 9 0.13 4.15 7.18 5.00
75 INT52132 Positive_regulation of Negative_regulation of Abat 9 0.50 0.53 7.03 5.00
76 INT52180 Binding of Aes 38 0.42 23.16 6.7 5.00
77 INT23246 Gene_expression of HLA-DRB4 37 0.64 36.79 6.61 5.00
78 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41 5.00
79 INT95313 Gene_expression of Slc6a1 6 0.76 3.96 6.14 5.00
80 INT62270 Positive_regulation of Gene_expression of Cdkn1a 30 0.47 18.73 5.69 5.00
81 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22 5.00
82 INT80038 Positive_regulation of Gene_expression of MYC 24 0.67 13.93 5.17 5.00
83 INT106524 Phosphorylation of Jun 23 0.80 15.35 4.78 5.00
84 INT112692 Localization of Bax 31 0.80 20.97 3.98 5.00
85 INT95423 Negative_regulation of Bcl2l1 26 0.41 21.66 3.81 5.00
86 INT64817 Positive_regulation of Binding of Jun 16 0.69 6.78 3.81 5.00
87 INT92017 Regulation of Gene_expression of Flvcr2 3 0.18 1.69 3.75 5.00
88 INT267678 Positive_regulation of Positive_regulation of Slc1a1 1 0.07 1.34 3.65 5.00
89 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54 5.00
90 INT62268 Positive_regulation of Cdkn1a 33 0.67 14.12 3.26 5.00
91 INT73263 Negative_regulation of MYC 20 0.57 12.86 2.95 5.00
92 INT93207 Negative_regulation of Cyp4a3 11 0.36 4.32 2.63 5.00
93 INT311478 Positive_regulation of Mllt1 4 0.60 2.38 2.34 5.00
94 INT82798 Regulation of MYC 19 0.60 12.06 2.31 5.00
95 INT178193 Negative_regulation of Stat3 25 0.58 17.82 2.27 5.00
96 INT201652 Positive_regulation of Tnfsf10 26 0.68 26.79 2.14 5.00
97 INT73476 Transcription of MYC 18 0.69 12.14 2.13 5.00
98 INT262348 Gene_expression of Lgsn 12 0.58 12.64 2.08 5.00
99 INT27236 Negative_regulation of F13a1 17 0.53 10.79 1.99 5.00
100 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87 5.00
101 INT226894 Negative_regulation of Tnfsf10 14 0.57 16.64 1.87 5.00
102 INT192965 Localization of Stat3 15 0.74 7.05 1.68 5.00
103 INT73475 Positive_regulation of Transcription of MYC 7 0.67 5.46 1.66 5.00
104 INT311474 Positive_regulation of Localization of Mllt1 1 0.43 1.23 1.56 5.00
105 INT311482 Negative_regulation of Positive_regulation of Mllt1 1 0.37 0.66 1.55 5.00
106 INT311472 Negative_regulation of Localization of Mllt1 1 0.37 0.9 1.45 5.00
107 INT126334 Gene_expression of Tnfrsf10b 8 0.58 8.68 1.42 5.00
108 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41 5.00
109 INT121207 Negative_regulation of Phosphorylation of Stat3 16 0.45 9.35 1.4 5.00
110 INT311480 Negative_regulation of Mllt1 1 0.50 0.55 1.31 5.00
111 INT123303 Gene_expression of Smn1 40 0.71 15.5 1.18 5.00
112 INT174156 Localization of Trp53 16 0.72 13.52 1.18 5.00
113 INT110259 Negative_regulation of Vwf 6 0.42 3.3 1.1 5.00
114 INT311475 Regulation of Localization of Mllt1 1 0.39 1.1 0.94 5.00
115 INT143114 Positive_regulation of Gene_expression of HLA-DRB4 5 0.29 5.2 0.92 5.00
116 INT236104 Positive_regulation of Negative_regulation of Ppara 6 0.59 6.91 0.91 5.00
117 INT264035 Regulation of Lgsn 5 0.39 6.2 0.86 5.00
118 INT311481 Positive_regulation of Positive_regulation of Ugt1a@ 1 0.03 0.38 0.77 5.00
119 INT311477 Positive_regulation of Negative_regulation of Mllt1 1 0.43 0.3 0.75 5.00
120 INT106523 Positive_regulation of Phosphorylation of Jun 7 0.45 3.1 0.74 5.00
121 INT128562 Regulation of Mllt1 2 0.39 1.1 0.74 5.00
122 INT311476 Positive_regulation of Positive_regulation of Mllt1 1 0.40 0.16 0.72 5.00
123 INT311473 Positive_regulation of Ugt1a@ 1 0.04 0.38 0.7 5.00
124 INT75453 Gene_expression of SMN2 4 0.75 2.55 0.67 5.00
125 INT307186 Negative_regulation of Phosphorylation of Jun 4 0.10 2.91 0.61 5.00
126 INT260801 Negative_regulation of Gene_expression of Tnfsf10 7 0.42 6.49 0.54 5.00
127 INT272868 Positive_regulation of Hdac2 3 0.27 2.15 0.5 5.00
128 INT175423 Positive_regulation of TSC1 25 0.36 21.81 0.45 5.00
129 INT145249 Negative_regulation of Cflar 6 0.42 7.16 0.42 5.00
130 INT151940 Positive_regulation of Igh-Lev 2 0.41 4.51 0.41 5.00
131 INT264203 Localization of Igh-Lev 1 0.34 0.22 0.33 5.00
132 INT131017 Positive_regulation of Positive_regulation of Cdkn1a 5 0.67 1.89 0.32 5.00
133 INT152670 Negative_regulation of HAT1 4 0.07 1.04 0.32 5.00
134 INT172625 Regulation of HAT1 9 0.35 9.21 0.28 5.00
135 INT125419 Positive_regulation of Cyp4a3 5 0.18 2.05 0.27 5.00
136 INT248468 Negative_regulation of Smn1 6 0.39 5.55 0.25 5.00
137 INT101742 Regulation of Cacna1c 3 0.22 1.35 0.23 5.00
138 INT135543 Negative_regulation of Positive_regulation of Bax 5 0.30 6.4 0.23 5.00
139 INT276934 Negative_regulation of Localization of Stat3 4 0.45 1.99 0.15 5.00
140 INT265376 Gene_expression of Hdac3 4 0.51 1.8 0.13 5.00
141 INT237664 Negative_regulation of Gene_expression of SMUG1 1 0.02 0.39 0.1 5.00
142 INT284491 Binding of METTL3 1 0.01 0.78 0.08 5.00
143 INT328541 Gene_expression of Rqcd1 1 0.01 0.91 0.07 5.00
144 INT328553 Positive_regulation of Gene_expression of SMN2 1 0.49 1.03 0.07 5.00
145 INT328542 Regulation of Positive_regulation of Cdkn1a 1 0.03 0.79 0.07 5.00
146 INT264205 Positive_regulation of Gene_expression of Igh-Lev 1 0.22 0.34 0.04 5.00
147 INT328544 Localization of Hsp90aa1 1 0.10 0.17 0.03 5.00
148 INT328554 Regulation of HDAC1 1 0.26 1.12 0.03 5.00
149 INT190057 Positive_regulation of Negative_regulation of TSC1 2 0.01 1.08 0.03 5.00
150 INT265373 Regulation of Hdac3 2 0.17 1.1 0.03 5.00
151 INT328536 Positive_regulation of Kera 1 0.04 1.14 0 5.00
152 INT328535 Localization of Nacc1 1 0.15 0.68 0 5.00
153 INT328548 Negative_regulation of Gene_expression of Cbx5 1 0.05 0.08 0 5.00
154 INT328546 Gene_expression of Cbx5 1 0.07 0.08 0 5.00
155 INT328537 Gene_expression of Cbx1 1 0.02 0.08 0 5.00
156 INT172965 Negative_regulation of Positive_regulation of Cdkn1a 4 0.41 1.84 0 5.00
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