D:Kawasaki Syndrome

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Disease Term
Synonyms ACUTE FEBRILE MCLS, Acute Febrile Mucocutaneous Lymph Node Syndrome, Infantile Polyarteritis Nodosa, Kawasaki Disease, Kawasaki S Syndrome, MCLS, Mlns, Mucocutaneous Lymph Node Syndrome
Documents 14
Hot Single Events 5
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Kawasaki Syndrome. They are ordered first by their relevance to Kawasaki Syndrome and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 5.00
2 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
3 INT254355 PF4 Positive_regulation of IFNA1 1 0.04 1.23 1.26 5.00
4 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79 5.00
5 INT254352 Binding of CXCR4 and Positive_regulation of Gene_expression of CXCL12 1 0.14 1.8 0.66 5.00
6 INT254356 Binding of IFNG and IL1B 1 0.00 1.87 0.51 5.00
7 INT254357 Binding of IFNA1 and IL1B 1 0.00 1.88 0.51 5.00
8 INT254348 Binding of ANGPT1 and TEK 1 0.04 1.72 0.48 5.00
9 INT300551 TBX21 Regulation of Hand1 2 0.10 0.44 0.48 5.00
10 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46 5.00
11 INT254347 FASLG Negative_regulation of Gene_expression of CHI3L1 1 0.13 0.92 0.42 5.00
12 INT254350 FASLG Negative_regulation of Gene_expression of VEGFA 1 0.06 0.92 0.42 5.00
13 INT300751 Binding of IGHE and Hand2 1 0.04 0 0.34 5.00
14 INT300727 IL25 Positive_regulation of IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
15 INT300732 IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
16 INT300728 IL33 Positive_regulation of IL4 1 0.00 0 0.33 5.00
17 INT300729 IL18 Positive_regulation of IL13 1 0.00 0 0.33 5.00
18 INT300742 Stat6 Regulation of Hand2 1 0.01 0.06 0.3 5.00
19 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3 5.00
20 INT254353 Binding of VEGFA and MMRN1 1 0.00 0.81 0.28 5.00
21 INT254359 IL1B Positive_regulation of Localization of VEGFA 1 0.01 0.87 0.26 5.00
22 INT254349 Positive_regulation of Binding of EPAS1 and HIF1A 1 0.00 0.92 0.23 5.00
23 INT254351 Binding of ANGPT2 and TEK 1 0.04 0.87 0.22 5.00
24 INT300753 Binding of Cd28 and Positive_regulation of Transcription of IL13 1 0.00 0 0.17 5.00
25 INT300731 IL10 Negative_regulation of Gene_expression of IGHE 1 0.03 0.23 0.13 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Kawasaki Syndrome. They are ordered first by their pain relevance and then by number of times they were reported in Kawasaki Syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 98.16
2 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 98.00
3 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66 81.68
4 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4 81.68
5 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88 81.68
6 INT204123 Positive_regulation of Transcription of CRP 5 0.49 8.11 0.57 79.16
7 INT204124 Transcription of CRP 14 0.69 20.79 2.71 79.16
8 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 78.76
9 INT129358 Gene_expression of ELOVL1 23 0.66 29.39 2.83 78.64
10 INT8775 Binding of IGHE 167 0.48 102.61 23.54 78.56
11 INT2971 Regulation of IGHE 42 0.61 28.81 7.87 77.92
12 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 68.00
13 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 67.04
14 INT125821 Regulation of Positive_regulation of IGHE 6 0.40 5.38 0.53 61.92
15 INT104221 Regulation of Gene_expression of CRP 30 0.45 20.01 4.07 60.72
16 INT171562 Regulation of IL4 19 0.36 12.12 5.33 59.92
17 INT73500 Regulation of IL13 12 0.36 10.37 3.53 59.92
18 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 59.52
19 INT73499 Positive_regulation of IL13 23 0.39 20.03 6.53 57.04
20 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 56.32
21 INT47949 Positive_regulation of ELOVL1 19 0.42 29.78 3.3 56.24
22 INT17324 Negative_regulation of Plg 26 0.38 13.5 4.05 53.40
23 INT254369 Negative_regulation of COL18A1 2 0.16 1.61 0.61 52.76
24 INT204119 Negative_regulation of Transcription of CRP 2 0.36 2.57 0.52 51.76
25 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 48.32
26 INT254370 Gene_expression of THBS2 1 0.06 2.24 1 46.92
27 INT88544 Gene_expression of MMRN1 102 0.75 68.8 14.55 45.32
28 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 45.20
29 INT204122 Gene_expression of GJA8 13 0.47 22.98 3.04 43.68
30 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 42.28
31 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 41.92
32 INT142006 Positive_regulation of COL18A1 2 0.41 3.01 0.53 38.32
33 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 34.92
34 INT112017 Regulation of Hand2 77 0.36 62.23 18.04 32.40
35 INT104045 Regulation of Hand1 65 0.35 51.32 16.26 32.08
36 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 31.40
37 INT171072 Negative_regulation of Fcr 2 0.07 1.71 0.31 27.96
38 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 25.84
39 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 21.96
40 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58 21.76
41 INT23257 Regulation of CRP 127 0.62 100.05 21.87 8.96
42 INT22335 Regulation of Negative_regulation of ACE 10 0.44 7.01 1.77 5.40
43 INT204127 Regulation of Negative_regulation of EGFL7 1 0.07 2.02 0.29 5.40
44 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
45 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
46 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
47 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
48 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
49 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 5.00
50 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
51 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74 5.00
52 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 5.00
53 INT72182 Gene_expression of Mcpt1 167 0.75 123.7 52.15 5.00
54 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 5.00
55 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
56 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24 5.00
57 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
58 INT9655 Regulation of Il6 98 0.62 70.92 31.95 5.00
59 INT1179 Negative_regulation of Ace 157 0.59 67.03 30.46 5.00
60 INT100861 Binding of CRP 179 0.48 175.2 26.45 5.00
61 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22 5.00
62 INT9079 Gene_expression of PPBP 52 0.75 31.2 21.52 5.00
63 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
64 INT157463 Gene_expression of CX3CL1 55 0.62 69.05 19.75 5.00
65 INT5160 Localization of PTAFR 61 0.80 42.6 19.16 5.00
66 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86 5.00
67 INT143230 Gene_expression of CRYGD 61 0.65 52.11 15.93 5.00
68 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32 5.00
69 INT106745 Localization of CRP 65 0.81 66.44 15.21 5.00
70 INT91544 Gene_expression of CHI3L1 60 0.75 77.72 13.9 5.00
71 INT108485 Gene_expression of CXCL12 61 0.75 49.34 13.79 5.00
72 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 5.00
73 INT173505 Localization of Hand2 63 0.57 45.32 13.66 5.00
74 INT69158 Localization of IL4 48 0.71 31.3 11.98 5.00
75 INT92574 Gene_expression of CXCL5 51 0.78 24.87 11.89 5.00
76 INT176607 Gene_expression of Cx3cl1 27 0.75 19.51 11.32 5.00
77 INT157466 Gene_expression of CX3CR1 14 0.76 20.6 10.76 5.00
78 INT701 Localization of IGHE 87 0.80 40.5 10.62 5.00
79 INT15804 Gene_expression of ISG20 83 0.75 44.33 10.58 5.00
80 INT112969 Negative_regulation of Mcpt1 30 0.45 20.17 10.11 5.00
81 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 5.00
82 INT85966 Gene_expression of Cd40lg 50 0.73 30.9 9.11 5.00
83 INT93003 Binding of CD40 28 0.47 20.25 7.13 5.00
84 INT127691 Gene_expression of CXCL1 23 0.66 18.11 7.04 5.00
85 INT93046 Positive_regulation of Gene_expression of Hand2 27 0.47 24.54 7.01 5.00
86 INT132822 Localization of IL13 26 0.67 22.85 6.66 5.00
87 INT117189 Binding of CXCR4 34 0.37 24.27 5.81 5.00
88 INT56299 Transcription of IL4 15 0.64 10.2 5.44 5.00
89 INT62041 Negative_regulation of Gene_expression of IGHE 37 0.58 37.86 5.27 5.00
90 INT3128 Negative_regulation of PON1 30 0.59 26.19 4.57 5.00
91 INT1149 Binding of ecs 19 0.37 13.67 3.9 5.00
92 INT170528 Negative_regulation of Gene_expression of CD4 25 0.41 17.98 3.6 5.00
93 INT9999 Regulation of Gene_expression of IGHE 32 0.60 15.75 3.53 5.00
94 INT188355 Binding of Cd28 25 0.34 8.29 3.38 5.00
95 INT85971 Positive_regulation of Gene_expression of Cd40lg 14 0.66 7.61 3.29 5.00
96 INT175262 Binding of SH2B2 18 0.36 22.85 3.18 5.00
97 INT208588 Binding of CXCR2 11 0.48 6.43 2.68 5.00
98 INT98226 Negative_regulation of Cd79a 5 0.49 3.99 2.66 5.00
99 INT72165 Gene_expression of CXCL6 8 0.52 4.76 2.6 5.00
100 INT28815 Gene_expression of Ighd 18 0.65 11.02 2.48 5.00
101 INT108482 Positive_regulation of Gene_expression of CXCL12 7 0.53 9.72 2.36 5.00
102 INT112364 Negative_regulation of HIF1A 22 0.57 16.95 2.13 5.00
103 INT153718 Gene_expression of ANGPT1 15 0.45 10.82 2.13 5.00
104 INT3723 Binding of PON1 9 0.46 5.83 2.13 5.00
105 INT37394 Localization of ecs 9 0.34 6.41 2.11 5.00
106 INT11390 Gene_expression of PF4 5 0.65 3.09 2.07 5.00
107 INT191534 Negative_regulation of EGFL7 10 0.06 7.52 1.98 5.00
108 INT221431 Negative_regulation of FOXP3 8 0.40 9.92 1.98 5.00
109 INT171070 Positive_regulation of Hey2 8 0.05 10.12 1.96 5.00
110 INT129240 Positive_regulation of Stat6 6 0.67 1.96 1.92 5.00
111 INT153719 Gene_expression of TEK 10 0.49 9.82 1.88 5.00
112 INT200223 Positive_regulation of EPAS1 21 0.17 21.95 1.7 5.00
113 INT100672 Transcription of Hand2 9 0.42 2.84 1.47 5.00
114 INT179169 Transcription of IL13 11 0.15 4.22 1.37 5.00
115 INT171576 Phosphorylation of CRP 6 0.80 5.55 1.22 5.00
116 INT9081 Positive_regulation of Positive_regulation of IGHE 5 0.42 7.13 1 5.00
117 INT246524 Binding of QPCT 4 0.05 3.65 0.72 5.00
118 INT204120 Positive_regulation of GJA8 2 0.30 1.51 0.63 5.00
119 INT254368 Gene_expression of XCR1 1 0.20 1.03 0.55 5.00
120 INT171071 Negative_regulation of Hey2 1 0.03 1.31 0.48 5.00
121 INT171073 Regulation of Positive_regulation of Hey2 1 0.03 1.22 0.45 5.00
122 INT254367 Transcription of TEK 1 0.14 1.08 0.36 5.00
123 INT254372 Negative_regulation of TEK 1 0.12 1.05 0.31 5.00
124 INT204128 Negative_regulation of GJA8 2 0.26 2.73 0.24 5.00
125 INT204121 Regulation of GJA8 1 0.27 3.52 0.21 5.00
126 INT263492 Positive_regulation of Regulation of Hand2 3 0.19 4.76 0.21 5.00
127 INT284968 Positive_regulation of CDA 2 0.05 0.34 0.15 5.00
128 INT171074 Gene_expression of Hey2 2 0.44 0.83 0.14 5.00
129 INT204125 Positive_regulation of Negative_regulation of GJA8 1 0.30 2.4 0.13 5.00
130 INT204126 Localization of GJA8 1 0.45 2.36 0.12 5.00
131 INT300743 Regulation of MS4A2 1 0.00 0.62 0.06 5.00
132 INT300746 Gene_expression of MS4A2 1 0.01 0.25 0 5.00
133 INT300748 Negative_regulation of Negative_regulation of IGHE 1 0.38 0.55 0 5.00
134 INT300749 Binding of MS4A2 1 0.00 0.38 0 5.00
135 INT300747 Positive_regulation of Negative_regulation of IGHE 1 0.41 0.63 0 5.00
136 INT204129 Positive_regulation of Gene_expression of GJA8 1 0.30 0.85 0 5.00
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