D:Kernicterus

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pChart

Disease Term
Synonyms Bilirubin Encephalopathies, Bilirubin Encephalopathy, Encephalopathies Bilirubin, Encephalopathies Hyperbilirubinemic, Encephalopathy Bilirubin, Encephalopathy Hyperbilirubinemic, Hyperbilirubinemic Encephalopathies, HYPERBILIRUBINEMIC ENCEPHALOPATHY
Documents 27
Hot Single Events 10
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Kernicterus. They are ordered first by their relevance to Kernicterus and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT271635 Negative_regulation of GRIN1 Negative_regulation of Positive_regulation of Ltp 1 0.00 0.65 0.93 5.00
2 INT227333 Il2 Positive_regulation of Hmox1 1 0.05 0.93 0.04 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Kernicterus. They are ordered first by their pain relevance and then by number of times they were reported in Kernicterus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT24978 Binding of SFTPA1 22 0.47 15.09 7.76 99.80
2 INT142172 Negative_regulation of Calb1 4 0.02 2.62 1.62 98.88
3 INT26719 Negative_regulation of Gene_expression of Th 38 0.58 11.87 22.78 98.64
4 INT4740 Gene_expression of Th 298 0.78 61.27 154.03 98.16
5 INT13276 Regulation of Ltp 107 0.53 30.78 69.13 94.12
6 INT13277 Regulation of Positive_regulation of Ltp 83 0.52 19.68 55.78 94.12
7 INT7114 Positive_regulation of Ltp 1192 0.62 290.76 755.77 93.24
8 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17 89.28
9 INT80228 Positive_regulation of Gene_expression of Hmox1 68 0.70 62.88 14.01 89.28
10 INT234 Binding of Alb 151 0.48 52.34 32.97 87.44
11 INT80223 Positive_regulation of Hmox1 128 0.68 77.71 17.64 62.60
12 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21 58.88
13 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54 58.88
14 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55 58.88
15 INT93036 Negative_regulation of Grin2a 23 0.50 7.1 10.32 58.88
16 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61 58.24
17 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42 58.24
18 INT51627 Gene_expression of Grin2a 82 0.76 25.09 47.6 58.24
19 INT7506 Negative_regulation of Ltp 267 0.46 91.01 176.8 47.24
20 INT193466 Binding of Acta1 5 0.27 2.62 0.23 46.00
21 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
22 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
23 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 5.00
24 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
25 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 5.00
26 INT7628 Gene_expression of Ltp 273 0.77 70.21 147.87 5.00
27 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
28 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38 5.00
29 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 5.00
30 INT7627 Negative_regulation of Positive_regulation of Ltp 162 0.50 41.2 106.27 5.00
31 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 5.00
32 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 5.00
33 INT13036 Positive_regulation of Positive_regulation of Ltp 105 0.51 23.71 77.66 5.00
34 INT14049 Positive_regulation of GRIN1 102 0.70 48.31 71.06 5.00
35 INT7340 Regulation of Grin1 87 0.62 30.37 57.93 5.00
36 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31 5.00
37 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14 5.00
38 INT11246 Binding of Grin1 65 0.48 14.53 36.93 5.00
39 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 5.00
40 INT47710 Negative_regulation of GRIN1 71 0.57 25.57 34.24 5.00
41 INT57024 Regulation of Gene_expression of Grin1 32 0.62 9.77 32.6 5.00
42 INT49110 Regulation of Grip2 46 0.61 13.57 30.87 5.00
43 INT7664 Negative_regulation of Grip2 68 0.49 10.11 29.93 5.00
44 INT7035 Regulation of CGA 87 0.45 29.04 28.45 5.00
45 INT87212 Negative_regulation of Positive_regulation of Nfkb1 74 0.57 38.21 28.31 5.00
46 INT32826 Positive_regulation of Gene_expression of Ltp 52 0.45 10.34 26.8 5.00
47 INT48832 Positive_regulation of Grip2 48 0.69 12.13 25.99 5.00
48 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84 5.00
49 INT6993 Negative_regulation of Mpo 72 0.59 61.83 19.51 5.00
50 INT90612 Positive_regulation of Grin2a 33 0.65 15.11 18.84 5.00
51 INT16624 Localization of Grin1 38 0.79 8.46 17.15 5.00
52 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92 5.00
53 INT18513 Binding of GRIN1 32 0.47 9.44 15.08 5.00
54 INT51625 Regulation of Gene_expression of Grin2a 12 0.60 3.28 11.6 5.00
55 INT73959 Positive_regulation of NOSTRIN 49 0.61 31.1 11.27 5.00
56 INT54466 Negative_regulation of Gene_expression of Ltp 19 0.38 5.44 10.91 5.00
57 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62 5.00
58 INT78769 Regulation of Grin2a 16 0.58 5.22 9.28 5.00
59 INT141185 Regulation of Ros1 30 0.24 20.73 8.88 5.00
60 INT52243 Phosphorylation of Ltp 13 0.54 2.84 8.7 5.00
61 INT91370 Phosphorylation of STAT3 123 0.82 49.25 8.42 5.00
62 INT49315 Localization of Gabrd 17 0.63 2.32 7.95 5.00
63 INT48626 Positive_regulation of Csf3 33 0.66 29.79 7.34 5.00
64 INT50419 Gene_expression of Grina 13 0.25 6.11 6.42 5.00
65 INT74109 Positive_regulation of Sele 26 0.48 22.32 5.84 5.00
66 INT202934 Localization of NOVA2 12 0.44 3.9 5.36 5.00
67 INT92541 Localization of Grin2b 11 0.75 2.85 5.14 5.00
68 INT111404 Regulation of Positive_regulation of Grin1 5 0.56 2.49 4.31 5.00
69 INT35019 Phosphorylation of Syn1 11 0.82 0.33 4.28 5.00
70 INT64338 Negative_regulation of Hmox1 16 0.56 12.72 4.2 5.00
71 INT35017 Negative_regulation of Phosphorylation of Syn1 5 0.59 0.24 3.22 5.00
72 INT16287 Positive_regulation of NOVA2 25 0.49 6.62 3.01 5.00
73 INT90611 Positive_regulation of Positive_regulation of Grin2a 4 0.63 1.89 3 5.00
74 INT105730 Localization of Grin2a 7 0.67 0.64 2.56 5.00
75 INT115193 Positive_regulation of Phosphorylation of STAT3 30 0.64 11.37 2.2 5.00
76 INT93031 Regulation of Grina 3 0.30 0.4 2.01 5.00
77 INT103624 Negative_regulation of Gene_expression of Grin2a 5 0.56 1.58 1.9 5.00
78 INT22021 Positive_regulation of Negative_regulation of Grin1 3 0.49 0.69 1.89 5.00
79 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89 5.00
80 INT149580 Positive_regulation of Phosphorylation of Ltp 2 0.33 0.64 1.73 5.00
81 INT133462 Negative_regulation of Gene_expression of Grina 2 0.12 1.56 1.62 5.00
82 INT115355 Regulation of Negative_regulation of Grin1 2 0.23 0.23 1.44 5.00
83 INT105729 Negative_regulation of Localization of Grin2a 3 0.38 0.08 1.29 5.00
84 INT249527 Positive_regulation of Positive_regulation of Grin2b 2 0.37 1.12 1.22 5.00
85 INT192851 Phosphorylation of Il6 7 0.68 3.12 0.82 5.00
86 INT165578 Regulation of Positive_regulation of Grin2b 3 0.41 1.07 0.74 5.00
87 INT271621 Positive_regulation of Binding of GRIN1 1 0.00 0.17 0.61 5.00
88 INT271625 Protein_catabolism of Grin2b 1 0.38 0.26 0.57 5.00
89 INT271623 Positive_regulation of Localization of NOVA2 2 0.20 0.83 0.54 5.00
90 INT271631 Negative_regulation of Localization of Grin1 2 0.32 0.58 0.52 5.00
91 INT227331 Binding of Xdh 5 0.29 1.83 0.49 5.00
92 INT271628 Negative_regulation of Regulation of Grin2a 2 0.28 1.05 0.47 5.00
93 INT271632 Negative_regulation of Regulation of Grin2b 2 0.28 1.06 0.47 5.00
94 INT129057 Regulation of Phosphorylation of Ltp 1 0.21 0.31 0.45 5.00
95 INT271627 Regulation of Positive_regulation of Grin2a 1 0.30 0.23 0.4 5.00
96 INT185370 Gene_expression of ANC 28 0.65 13.28 0.4 5.00
97 INT271630 Negative_regulation of Localization of Grin2b 1 0.25 0 0.37 5.00
98 INT227332 Phosphorylation of Csf3 2 0.43 2.01 0.31 5.00
99 INT216879 Binding of Hmox1 4 0.36 2.82 0.31 5.00
100 INT271629 Positive_regulation of Protein_catabolism of Grin2b 1 0.27 0.13 0.28 5.00
101 INT271624 Negative_regulation of Grina 1 0.06 0 0.26 5.00
102 INT201453 Protein_catabolism of Hmox1 3 0.95 4.25 0.23 5.00
103 INT55890 Regulation of RPS6KB2 2 0.39 0.44 0.16 5.00
104 INT271607 Negative_regulation of Phosphorylation of Ltp 1 0.04 0.09 0.09 5.00
105 INT235606 Gene_expression of Rxfp2 1 0.05 0.47 0.07 5.00
106 INT259905 Negative_regulation of Lbw1 1 0.01 0.36 0 5.00
107 INT264247 Positive_regulation of Gene_expression of ANC 5 0.38 1.71 0 5.00
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