D:Klinefelter Syndrome

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Disease Term
Synonyms Klinefelter S Syndrome, KLINEFELTER SYNDROMES, KLINEFELTERS SYNDROME, Syndrome Klinefelter, Syndrome Klinefelter S, Syndromes Klinefelter
Documents 19
Hot Single Events 14
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Klinefelter Syndrome. They are ordered first by their relevance to Klinefelter Syndrome and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT222466 Gnrh1 Regulation of Prl 1 0.14 1.16 0.07 81.08
2 INT1392 Trh Regulation of Prl 15 0.29 2.47 4.29 77.28
3 INT60536 Gnrh1 Positive_regulation of Localization of Prl 2 0.22 1.12 0.6 59.00
4 INT222561 Gnrh1 Positive_regulation of Prl 1 0.15 0.38 0.22 39.84
5 INT222506 Gnrh1 Regulation of Localization of Prl 1 0.20 0.16 0.08 16.60
6 INT2161 Gnrh1 Positive_regulation of Localization of LH 33 0.73 0.87 14.34 5.00
7 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 0.64 2.12 14.2 5.00
8 INT2714 Pomc Positive_regulation of Localization of Prl 17 0.79 0.5 8.18 5.00
9 INT20133 Trh Positive_regulation of Localization of Prl 23 0.78 2.04 5.44 5.00
10 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79 5.00
11 INT9786 Gnrh1 Regulation of LH 7 0.40 0.58 1.82 5.00
12 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25 5.00
13 INT62368 Gal Positive_regulation of Localization of LH 3 0.36 0 1.2 5.00
14 INT222516 Binding of Calcrl and Ramp1 5 0.17 0.11 1.12 5.00
15 INT36186 Npy Positive_regulation of Localization of Gnrh1 4 0.75 0.09 0.96 5.00
16 INT206857 Binding of Calca and Calcrl 4 0.37 1.9 0.95 5.00
17 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9 5.00
18 INT222528 Abat Positive_regulation of Gene_expression of Gh1 1 0.01 0 0.75 5.00
19 INT222432 Binding of Tlr4 and Cd14 1 0.02 0.74 0.71 5.00
20 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71 5.00
21 INT32715 Prl Regulation of Localization of LH 2 0.34 0.09 0.68 5.00
22 INT60283 Positive_regulation of Gnrh1 Regulation of LH 2 0.31 0 0.68 5.00
23 INT222552 Abat Regulation of Gene_expression of Gh1 1 0.00 0 0.67 5.00
24 INT222492 Ngf Positive_regulation of Gene_expression of Prl 1 0.24 0 0.62 5.00
25 INT3617 Trh Regulation of Localization of Gh1 3 0.65 0.55 0.62 5.00
26 INT27067 Crh Positive_regulation of Localization of Avp 3 0.18 0.46 0.61 5.00
27 INT32747 Avp Positive_regulation of Localization of Pomc 4 0.16 1.92 0.61 5.00
28 INT222521 Vip Positive_regulation of Localization of Ngf 1 0.14 0.08 0.6 5.00
29 INT222554 Il1a Positive_regulation of Localization of Ngf 1 0.02 0.07 0.6 5.00
30 INT222524 Abat Negative_regulation of Localization of Trh 1 0.02 0.16 0.51 5.00
31 INT222490 Npy Positive_regulation of Localization of Gh1 1 0.02 0.06 0.41 5.00
32 INT222418 Tlr4 Positive_regulation of Gene_expression of Il1a 1 0.00 0.31 0.39 5.00
33 INT3616 Trh Positive_regulation of Localization of Gh1 4 0.73 0.49 0.36 5.00
34 INT222441 Tlr4 Positive_regulation of Gene_expression of Tac1 1 0.00 0.39 0.32 5.00
35 INT222464 Col4a2 Regulation of Localization of Prl 1 0.03 0.32 0.3 5.00
36 INT222529 Binding of Trh and Vip 1 0.07 0.09 0.29 5.00
37 INT126696 Binding of Crhr1 and Crh 3 0.50 0.44 0.29 5.00
38 INT222428 Negative_regulation of Tlr4 Positive_regulation of Il6 1 0.01 0.26 0.27 5.00
39 INT222412 Cd14 Negative_regulation of Binding of Tlr4 1 0.02 0.26 0.27 5.00
40 INT222440 Tlr4 Positive_regulation of Localization of Pomc 1 0.01 0.35 0.27 5.00
41 INT222427 Il6 Positive_regulation of Localization of Pomc 1 0.02 0.27 0.26 5.00
42 INT222422 Tlr4 Positive_regulation of Il6 1 0.01 0.25 0.26 5.00
43 INT222467 Gh1 Positive_regulation of Prl 1 0.04 0.52 0.26 5.00
44 INT222557 Gal Positive_regulation of Gene_expression of Vip 1 0.06 0.07 0.25 5.00
45 INT222421 Tlr4 Negative_regulation of Localization of Prl 1 0.02 0.45 0.25 5.00
46 INT222563 Vip Positive_regulation of Gene_expression of Il6 1 0.05 0.38 0.25 5.00
47 INT222560 Calca Positive_regulation of Gene_expression of Il6 1 0.06 0.39 0.25 5.00
48 INT222540 Mzb1 Positive_regulation of Gene_expression of Il6 1 0.03 0.38 0.25 5.00
49 INT222527 Gal Regulation of Vip 1 0.03 0.05 0.22 5.00
50 INT222566 Agt Positive_regulation of Localization of Prl 1 0.08 0.23 0.21 5.00
51 INT222482 Lep Positive_regulation of Localization of Gh1 1 0.02 1.02 0.2 5.00
52 INT222568 Vip Negative_regulation of Transcription of Nos2 1 0.06 0.3 0.19 5.00
53 INT222543 Il1a Regulation of Chat 1 0.01 0.64 0.19 5.00
54 INT222525 Il1a Regulation of Localization of Gh1 1 0.00 0.64 0.19 5.00
55 INT222499 Il10 Regulation of Positive_regulation of Hpse 1 0.00 0.8 0.19 5.00
56 INT222473 Mzb1 Negative_regulation of Transcription of Nos2 1 0.04 0.29 0.19 5.00
57 INT222494 Negative_regulation of Il1a Negative_regulation of Positive_regulation of Il6 1 0.00 0.79 0.19 5.00
58 INT222531 Il6 Positive_regulation of Hpse 1 0.00 0.61 0.18 5.00
59 INT222661 IFNA1 Positive_regulation of Gene_expression of Nos1 1 0.01 0.25 0.18 5.00
60 INT222414 Tlr4 Positive_regulation of Hpse 1 0.00 0.61 0.18 5.00
61 INT222470 Prl Regulation of Gnrh1 1 0.14 0.09 0.18 5.00
62 INT1394 Binding of Prl and LH 3 0.36 0 0.17 5.00
63 INT222443 INCENP Positive_regulation of Localization of Pomc 1 0.00 0.75 0.17 5.00
64 INT222426 Lif Positive_regulation of Localization of Pomc 1 0.02 0.75 0.17 5.00
65 INT222505 Gene_expression of Crh Negative_regulation of Gene_expression of Hpse 1 0.02 0.55 0.17 5.00
66 INT222509 Ghrh Positive_regulation of Localization of Prl 1 0.28 0.23 0.16 5.00
67 INT222430 Il11 Positive_regulation of Localization of Pomc 1 0.01 0.69 0.16 5.00
68 INT222548 Il11 Positive_regulation of Transcription of Pomc 1 0.03 0.7 0.16 5.00
69 INT222420 Tlr4 Positive_regulation of Positive_regulation of Hpse 1 0.00 0.67 0.15 5.00
70 INT39154 Crh Positive_regulation of Avp 2 0.11 0.15 0.14 5.00
71 INT222673 Gnrh1 Negative_regulation of Gnrh1 Positive_regulation of Prl 1 0.08 0.21 0.14 5.00
72 INT222551 Il6 Positive_regulation of Positive_regulation of Hpse 1 0.01 0.5 0.13 5.00
73 INT222465 Binding of Calcrl and Rxfp2 1 0.02 0 0.12 5.00
74 INT222546 Mzb1 Positive_regulation of Localization of Prl 1 0.10 0.17 0.12 5.00
75 INT222549 Pomc Positive_regulation of Gnrh1 1 0.13 0 0.12 5.00
76 INT222507 Igf1 Positive_regulation of Localization of Edn3 1 0.05 0 0.11 5.00
77 INT222472 Lep Positive_regulation of Localization of Cartpt 1 0.05 0 0.11 5.00
78 INT222503 Agt Positive_regulation of Localization of Gh1 1 0.02 0.23 0.11 5.00
79 INT186240 Binding of AGRP and SCN5A 2 0.13 1.19 0.1 5.00
80 INT222558 Mzb1 Regulation of Localization of Prl 1 0.13 0.14 0.1 5.00
81 INT222501 Cartpt Negative_regulation of Localization of Prl 1 0.08 0 0.1 5.00
82 INT222553 Binding of Sdc1 and Egf 1 0.02 0 0.1 5.00
83 INT222517 Calca Positive_regulation of Localization of Gh1 1 0.03 0 0.09 5.00
84 INT222442 Tlr4 Positive_regulation of Gene_expression of INCENP 1 0.00 0.34 0.09 5.00
85 INT222425 Mif Regulation of Tlr4 1 0.01 0.24 0.09 5.00
86 INT222483 Trh Regulation of Gene_expression of Gh1 1 0.03 0 0.09 5.00
87 INT222484 Pomc Positive_regulation of Transcription of Prl 1 0.14 0 0.09 5.00
88 INT222511 Il1a Positive_regulation of Gene_expression of Fst 1 0.01 0.32 0.08 5.00
89 INT1388 Binding of Prl and Gnrh1 3 0.35 0.17 0.08 5.00
90 INT222545 Lep Negative_regulation of Nmb 1 0.04 0.52 0.08 5.00
91 INT8092 Npy Regulation of Localization of Gnrh1 2 0.30 0.08 0.08 5.00
92 INT222514 Mif Regulation of Localization of Il6 1 0.04 0.23 0.08 5.00
93 INT222662 Il1a Positive_regulation of Gene_expression of INCENP 1 0.00 0.32 0.08 5.00
94 INT222489 Npr2 Positive_regulation of Pde5a 1 0.00 0.16 0.07 5.00
95 INT222429 Nps Positive_regulation of Pde5a 1 0.00 0.16 0.07 5.00
96 INT32745 Crh Positive_regulation of Localization of Pomc 2 0.16 0.49 0.07 5.00
97 INT222416 Tlr4 Positive_regulation of Gene_expression of Inhba 1 0.00 0.29 0.06 5.00
98 INT222488 Gal Positive_regulation of Gene_expression of Prl 1 0.05 0.05 0.06 5.00
99 INT222479 Binding of Ramp1 and Rxfp2 1 0.01 0 0.06 5.00
100 INT222431 Tlr4 Positive_regulation of Gene_expression of Fst 1 0.01 0.29 0.06 5.00
101 INT222533 Mzb1 Positive_regulation of Gene_expression of Gh1 1 0.03 0 0.06 5.00
102 INT222478 Binding of Calca and Rxfp2 1 0.02 0 0.06 5.00
103 INT222513 Mzb1 Positive_regulation of Localization of Gh1 1 0.03 0 0.06 5.00
104 INT222570 Cnp Positive_regulation of Localization of Gh1 1 0.03 0 0.06 5.00
105 INT222663 Mzb1 Positive_regulation of Localization of VEGFA 1 0.02 0 0.05 5.00
106 INT222463 Inhba Positive_regulation of Gene_expression of Fst 1 0.01 0 0.05 5.00
107 INT222520 Mzb1 Positive_regulation of Gene_expression of Fst 1 0.04 0 0.05 5.00
108 INT222476 Gnrh1 Negative_regulation of Gene_expression of Fst 1 0.04 0 0.05 5.00
109 INT222544 Binding of Ucn and Crh 1 0.02 0 0.05 5.00
110 INT222508 Ghrh Regulation of Localization of LH 1 0.07 0 0.05 5.00
111 INT222487 Trh Negative_regulation of Nmb 1 0.05 0.26 0.05 5.00
112 INT222512 Nppa Positive_regulation of Localization of LH 1 0.02 0 0.05 5.00
113 INT222664 Il6 Positive_regulation of Localization of VEGFA 1 0.01 0 0.05 5.00
114 INT222559 Binding of Ramp3 and Ramp1 1 0.02 0 0.05 5.00
115 INT222485 Binding of Iapp and Ramp1 1 0.09 0 0.05 5.00
116 INT222567 Negative_regulation of Gh1 Negative_regulation of Ghrh 1 0.03 0.19 0.04 5.00
117 INT222498 Ghrh Positive_regulation of Gene_expression of Ghrl 1 0.10 0.19 0.04 5.00
118 INT222417 Ucn Positive_regulation of Localization of Pomc 1 0.01 0 0.04 5.00
119 INT222534 Gnrh1 Positive_regulation of Localization of Lep 1 0.07 0 0.04 5.00
120 INT222497 Negative_regulation of Gh1 Negative_regulation of Ghrl 1 0.01 0.2 0.04 5.00
121 INT222562 Trh Regulation of Localization of LH 1 0.04 0 0.03 5.00
122 INT334918 GNRH1 Positive_regulation of Gene_expression of FSHR 2 0.11 1.27 0.03 5.00
123 INT222468 Nmb Positive_regulation of Localization of Trh 1 0.05 0.28 0.03 5.00
124 INT222532 Anxa1 Negative_regulation of Localization of Gh1 1 0.01 0.14 0.03 5.00
125 INT222469 Binding of Ucn and Crhr2 1 0.00 0 0.03 5.00
126 INT222477 Mzb1 Positive_regulation of Gene_expression of Prl 1 0.10 0.1 0.03 5.00
127 INT222565 Crh Positive_regulation of Transcription of Pomc 1 0.10 0.35 0.03 5.00
128 INT222538 Anxa1 Negative_regulation of Localization of Prl 1 0.04 0.14 0.03 5.00
129 INT246480 Binding of ALB and SHBG 2 0.14 1.45 0.03 5.00
130 INT222564 Mzb1 Regulation of Localization of Gh1 1 0.01 0 0.03 5.00
131 INT222475 Anxa1 Negative_regulation of Localization of LH 1 0.01 0.14 0.03 5.00
132 INT222510 Nmb Positive_regulation of Trh 1 0.05 0.28 0.03 5.00
133 INT222500 Avp Positive_regulation of Transcription of Pomc 1 0.17 0.35 0.03 5.00
134 INT222536 Ghrl Positive_regulation of Transcription of Pou1f1 1 0.03 0.13 0 5.00
135 INT222571 Il11 Regulation of Localization of Prl 1 0.03 0.06 0 5.00
136 INT334921 GNRHR Positive_regulation of Gene_expression of CGA 1 0.01 0.53 0 5.00
137 INT222573 Binding of Gh1 and LH 1 0.01 0 0 5.00
138 INT222480 Gnrh1 Regulation of Gene_expression of Prl 1 0.09 0.19 0 5.00
139 INT222556 Pde5a Regulation of Localization of LH 1 0.00 0.06 0 5.00
140 INT222672 Crem Positive_regulation of Crem Positive_regulation of Gh1 1 0.00 0.56 0 5.00
141 INT334922 GNRHR Positive_regulation of Gene_expression of PLOD1 1 0.08 0.53 0 5.00
142 INT222535 Binding of Gh1 and Fshb 1 0.01 0 0 5.00
143 INT334919 GNRH1 Positive_regulation of Gene_expression of CGA 1 0.03 0.52 0 5.00
144 INT222550 Binding of Gh1 and Gnrh1 1 0.03 0 0 5.00
145 INT222539 Negative_regulation of Binding of Inhba and Acvr2a 1 0.01 0 0 5.00
146 INT222474 Binding of Fgf1 and Ecm1 1 0.00 0.62 0 5.00
147 INT222423 Binding of Pomc and Fshb 1 0.01 0 0 5.00
148 INT222502 Binding of Crhr1 and Ucn2 1 0.01 0.05 0 5.00
149 INT222574 Crem Positive_regulation of Pou1f1 1 0.00 0.57 0 5.00
150 INT222665 INCENP Positive_regulation of Localization of Gnrh1 1 0.00 0.09 0 5.00
151 INT222504 Binding of Inhba and Acvr2a 1 0.01 0 0 5.00
152 INT222569 Cntf Regulation of Localization of Prl 1 0.01 0.06 0 5.00
153 INT334917 GNRHR Positive_regulation of Gene_expression of FSHR 1 0.05 0.53 0 5.00
154 INT222438 Nps Positive_regulation of Localization of Pomc 1 0.01 0.66 0 5.00
155 INT222526 Binding of Prl and Fshb 1 0.03 0 0 5.00
156 INT222424 Binding of Pomc and Gnrh1 1 0.03 0 0 5.00
157 INT222519 Il11 Regulation of Localization of Gh1 1 0.01 0.06 0 5.00
158 INT222413 Nps Positive_regulation of Localization of Crh 1 0.03 0.66 0 5.00
159 INT222541 Npy Positive_regulation of Localization of Prl 1 0.07 0 0 5.00
160 INT222481 Fgf2 Positive_regulation of Gene_expression of Prl 1 0.10 0 0 5.00
161 INT222496 Trh Positive_regulation of Gene_expression of Prl 1 0.10 0 0 5.00
162 INT222537 Binding of Nmu and Hpse 1 0.01 0.15 0 5.00
163 INT222515 Gnrh1 Positive_regulation of Localization of Gh1 1 0.05 0.21 0 5.00
164 INT222547 Cartpt Positive_regulation of Localization of Prl 1 0.08 0 0 5.00
165 INT222572 Oxt Regulation of Localization of LH 1 0.00 0.14 0 5.00
166 INT222495 Gene_expression of Calca Negative_regulation of Gene_expression of Prl 1 0.11 0.1 0 5.00
167 INT222471 Gnrh1 Positive_regulation of Pde5a 1 0.00 0.07 0 5.00
168 INT222530 Cntf Regulation of Localization of Gh1 1 0.00 0.06 0 5.00
169 INT222415 Binding of Pomc and LH 1 0.01 0 0 5.00
170 INT334920 GNRH1 Positive_regulation of Gene_expression of PLOD1 1 0.16 0.52 0 5.00
171 INT222419 Nmu Positive_regulation of Localization of Pomc 1 0.03 0.17 0 5.00
172 INT222486 Crem Positive_regulation of Gh1 1 0.00 1.13 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Klinefelter Syndrome. They are ordered first by their pain relevance and then by number of times they were reported in Klinefelter Syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT4771 Gene_expression of CGB 23 0.67 14.22 3.42 98.20
2 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 97.92
3 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 96.20
4 INT334927 Negative_regulation of MEHMO 1 0.01 3.46 0.1 95.60
5 INT11918 Localization of CGB 35 0.51 8.21 15.01 91.40
6 INT1793 Localization of CGA 379 0.81 67.38 114.69 90.64
7 INT133474 Localization of SDHA 1 0.14 2.19 0.07 89.36
8 INT12033 Binding of PLOD1 15 0.48 8.04 2.3 88.04
9 INT7033 Binding of FSHR 19 0.37 6.66 1.52 88.04
10 INT2197 Gene_expression of Gnrh1 184 0.78 40.04 50.57 87.76
11 INT4145 Gene_expression of FSHR 124 0.77 44.98 13.04 86.68
12 INT7970 Gene_expression of PLOD1 120 0.71 44.42 15.54 86.36
13 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 81.08
14 INT2123 Positive_regulation of Gnrh1 209 0.70 24.2 68.97 80.92
15 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 79.80
16 INT334926 Positive_regulation of MEHMO 1 0.02 10.11 2.37 78.04
17 INT2323 Gene_expression of Trh 146 0.78 29.92 49.5 77.12
18 INT162 Regulation of Prl 794 0.62 165.01 322.24 69.44
19 INT416 Regulation of LH 253 0.62 31.48 125.55 69.44
20 INT1644 Regulation of FSHR 77 0.55 15.62 21.49 62.08
21 INT25047 Positive_regulation of Regulation of FSHR 3 0.31 0.92 0.29 62.08
22 INT2056 Negative_regulation of Gnrh1 175 0.59 33.43 63.32 59.00
23 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 58.80
24 INT158 Localization of Prl 2431 0.81 378.96 952.2 58.36
25 INT3500 Positive_regulation of Gene_expression of Gnrh1 25 0.69 4.59 6.69 38.96
26 INT26538 Positive_regulation of FSHR 103 0.69 30.95 15.33 36.24
27 INT3933 Positive_regulation of PLOD1 128 0.70 30.76 42.03 35.60
28 INT211184 Positive_regulation of Binding of SCN5A 1 0.22 0.48 0 24.40
29 INT23598 Binding of SCN5A 32 0.40 16 5.35 22.72
30 INT174838 Localization of INCENP 80 0.64 19.05 12.89 15.72
31 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
32 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 5.00
33 INT1045 Localization of LH 1211 0.81 87.04 456.25 5.00
34 INT443 Localization of POMC 1020 0.81 284.52 443.17 5.00
35 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 5.00
36 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 5.00
37 INT439 Localization of Gnrh1 976 0.81 100.96 363.25 5.00
38 INT876 Localization of Gh1 843 0.80 67.75 340.82 5.00
39 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 5.00
40 INT477 Localization of Avp 813 0.81 131.58 300.4 5.00
41 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 5.00
42 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 5.00
43 INT3579 Localization of Oxt 555 0.81 43.35 292.44 5.00
44 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
45 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
46 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 5.00
47 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43 5.00
48 INT1005 Localization of Sst 385 0.81 26.31 244.56 5.00
49 INT1562 Localization of Crh 499 0.81 126.74 236.68 5.00
50 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 5.00
51 INT1308 Localization of Pomc 457 0.81 66.83 217.5 5.00
52 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 5.00
53 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 5.00
54 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 5.00
55 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 5.00
56 INT2085 Positive_regulation of LH 441 0.70 60.15 191.02 5.00
57 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 5.00
58 INT438 Gene_expression of Crh 376 0.78 159.11 169.17 5.00
59 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63 5.00
60 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 5.00
61 INT1044 Negative_regulation of Localization of LH 358 0.59 25.95 151.31 5.00
62 INT880 Positive_regulation of Localization of Gh1 304 0.70 14.79 150.23 5.00
63 INT6108 Gene_expression of Npy 292 0.78 110.65 148.21 5.00
64 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 5.00
65 INT2379 Positive_regulation of Localization of LH 349 0.70 27.86 144.53 5.00
66 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2 5.00
67 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 5.00
68 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 5.00
69 INT1047 Negative_regulation of LH 314 0.59 53.71 135.89 5.00
70 INT2541 Binding of Calca 200 0.48 67.14 134.62 5.00
71 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 5.00
72 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 5.00
73 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71 5.00
74 INT2106 Regulation of Localization of LH 279 0.62 22.37 122.77 5.00
75 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 5.00
76 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
77 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 5.00
78 INT1438 Localization of Pomc 360 0.81 101.26 116.47 5.00
79 INT4207 Regulation of Avp 267 0.62 63.72 115.33 5.00
80 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 5.00
81 INT5283 Positive_regulation of Npy 191 0.70 66.77 109.2 5.00
82 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
83 INT9012 Localization of Vip 283 0.81 31.71 106.16 5.00
84 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
85 INT4742 Gene_expression of Tac1 177 0.78 69.99 102.66 5.00
86 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98 5.00
87 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71 5.00
88 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84 5.00
89 INT2122 Negative_regulation of Localization of Gnrh1 226 0.59 26.92 92.04 5.00
90 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 5.00
91 INT1635 Gene_expression of Vip 245 0.78 53.36 88.13 5.00
92 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01 5.00
93 INT4798 Gene_expression of Nts 169 0.77 29.56 86.04 5.00
94 INT875 Regulation of Localization of Gh1 166 0.62 12.87 84.97 5.00
95 INT4289 Positive_regulation of Localization of Gnrh1 202 0.70 12.3 84.01 5.00
96 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 5.00
97 INT8650 Gene_expression of Gal 152 0.78 61.97 81.72 5.00
98 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 5.00
99 INT6107 Localization of Npy 180 0.81 26.76 81.67 5.00
100 INT403 Localization of Trh 241 0.81 28.55 81.45 5.00
101 INT920 Localization of PLOD1 223 0.81 42.25 78.7 5.00
102 INT2155 Negative_regulation of Sst 111 0.59 16.58 77.74 5.00
103 INT4358 Positive_regulation of Localization of Avp 195 0.70 30.79 77.58 5.00
104 INT881 Negative_regulation of Localization of Gh1 164 0.58 15.1 75.28 5.00
105 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 5.00
106 INT3034 Localization of Ngf 126 0.81 50.81 72.84 5.00
107 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38 5.00
108 INT2055 Regulation of Gnrh1 185 0.62 23.65 71.26 5.00
109 INT1376 Binding of Trh 121 0.48 20 69.86 5.00
110 INT1377 Positive_regulation of Trh 172 0.70 40.55 69.83 5.00
111 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 5.00
112 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
113 INT19511 Localization of Il6 212 0.81 118.17 67.67 5.00
114 INT462 Regulation of Pomc 157 0.62 41.67 67.27 5.00
115 INT1046 Gene_expression of LH 180 0.77 29.75 66.87 5.00
116 INT5941 Gene_expression of Oxt 164 0.76 22.63 65.47 5.00
117 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 5.00
118 INT5095 Localization of Ghrh 185 0.81 28.09 62.08 5.00
119 INT1437 Negative_regulation of Pomc 132 0.59 35.22 60.97 5.00
120 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3 5.00
121 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
122 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28 5.00
123 INT1307 Positive_regulation of Localization of Pomc 120 0.70 24.58 58.48 5.00
124 INT1463 Binding of Pomc 129 0.48 15.89 56.27 5.00
125 INT1782 Regulation of Gh1 125 0.62 22 55.74 5.00
126 INT5506 Positive_regulation of Gene_expression of Pomc 132 0.70 26.78 54.3 5.00
127 INT5509 Positive_regulation of Localization of Crh 91 0.70 30.65 53.92 5.00
128 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 5.00
129 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67 5.00
130 INT1781 Negative_regulation of Gh1 127 0.59 16.94 51.77 5.00
131 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57 5.00
132 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05 5.00
133 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
134 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 5.00
135 INT1977 Negative_regulation of Positive_regulation of Prl 98 0.59 17.06 47.88 5.00
136 INT873 Gene_expression of Gh1 130 0.76 26.15 46.75 5.00
137 INT5781 Gene_expression of Edn1 190 0.78 99.1 46 5.00
138 INT619 Positive_regulation of Positive_regulation of Prl 116 0.70 22.69 45.06 5.00
139 INT989 Negative_regulation of Trh 90 0.59 15.45 43.63 5.00
140 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67 5.00
141 INT2364 Localization of Sct 134 0.80 26.21 41.47 5.00
142 INT12228 Positive_regulation of Gene_expression of Abat 44 0.65 17.51 40.55 5.00
143 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
144 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55 5.00
145 INT385 Gene_expression of Agt 182 0.78 63.62 37.91 5.00
146 INT64558 Negative_regulation of Nos1 88 0.58 26.76 36.78 5.00
147 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
148 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08 5.00
149 INT1976 Regulation of Gene_expression of Prl 80 0.62 20.19 36 5.00
150 INT2296 Positive_regulation of Gene_expression of Prl 137 0.70 36.96 35.39 5.00
151 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51 5.00
152 INT6683 Gene_expression of Drd2 64 0.78 11.31 32.28 5.00
153 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68 5.00
154 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
155 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 5.00
156 INT6277 Positive_regulation of Gene_expression of Pomc 76 0.70 21.45 31.09 5.00
157 INT15347 Positive_regulation of Localization of Pomc 81 0.70 28.1 31.01 5.00
158 INT5507 Regulation of Localization of Crh 57 0.61 8.43 30.26 5.00
159 INT5100 Positive_regulation of Ghrh 100 0.64 24.2 30.21 5.00
160 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04 5.00
161 INT7397 Negative_regulation of Localization of GNRH1 86 0.59 15.45 29.78 5.00
162 INT894 Binding of Avp 84 0.48 29.16 29.63 5.00
163 INT5514 Negative_regulation of Localization of Crh 64 0.58 8.12 29.29 5.00
164 INT56525 Gene_expression of Gria2 74 0.75 23.15 28.6 5.00
165 INT16879 Binding of Crh 72 0.48 21.65 28.43 5.00
166 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19 5.00
167 INT116737 Localization of Mif 63 0.81 52.97 28.11 5.00
168 INT7565 Transcription of Pomc 69 0.72 14.46 27.41 5.00
169 INT7894 Negative_regulation of Vip 59 0.59 11.76 27.36 5.00
170 INT5966 Localization of Il1a 50 0.78 22.91 26.54 5.00
171 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 5.00
172 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 5.00
173 INT13415 Positive_regulation of Hpse 58 0.70 24.9 25.53 5.00
174 INT61953 Transcription of Nos2 101 0.72 46.64 25.49 5.00
175 INT5622 Gene_expression of Nppa 101 0.78 49.46 25.31 5.00
176 INT8380 Positive_regulation of Gene_expression of Npy 49 0.70 19.62 24.13 5.00
177 INT15511 Gene_expression of Tnfrsf1a 84 0.76 63.3 24.03 5.00
178 INT9155 Gene_expression of Glul 60 0.77 17.97 23.95 5.00
179 INT9526 Negative_regulation of Localization of Pomc 41 0.58 6.93 23.3 5.00
180 INT100026 Gene_expression of Tnfrsf1b 73 0.72 43.26 23.23 5.00
181 INT5511 Negative_regulation of Gene_expression of Pomc 47 0.59 12.08 23.02 5.00
182 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76 5.00
183 INT15326 Phosphorylation of Trib3 83 0.55 30.96 22.27 5.00
184 INT1327 Regulation of Localization of Trh 45 0.62 6.05 22.09 5.00
185 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73 5.00
186 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73 5.00
187 INT78057 Localization of Tlr4 140 0.77 67.75 21.72 5.00
188 INT74059 Positive_regulation of Gene_expression of Nos1 55 0.70 11.5 21.39 5.00
189 INT48144 Gene_expression of Fgf2 117 0.78 43 20.48 5.00
190 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28 5.00
191 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 5.00
192 INT7364 Regulation of Ghrh 49 0.58 8.05 19.05 5.00
193 INT5099 Localization of Gal 46 0.81 10.66 18.93 5.00
194 INT11628 Regulation of Localization of Pomc 44 0.61 10.46 18.66 5.00
195 INT12575 Regulation of Hpse 33 0.59 17.7 18.45 5.00
196 INT5967 Negative_regulation of Il1a 51 0.57 27.09 18.24 5.00
197 INT9179 Positive_regulation of Localization of Ghrh 42 0.70 7.05 18.1 5.00
198 INT1642 Negative_regulation of Localization of PLOD1 40 0.58 10.67 17.95 5.00
199 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 5.00
200 INT871 Negative_regulation of Gene_expression of Prl 53 0.58 18.89 17.79 5.00
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