D:Knee Osteoarthritis

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Disease Term
Synonyms Knee Osteoarthritides, Osteoarthritides Knee
Documents 976
Hot Single Events 200
Hot Interactions 14

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Knee Osteoarthritis. They are ordered first by their relevance to Knee Osteoarthritis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT227903 TNF Positive_regulation of Gene_expression of ADAMTS5 1 0.01 0.56 0.24 99.60
2 INT240057 Binding of RHOB and NME8 1 0.41 4.11 1.5 99.56
3 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09 97.52
4 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63 89.80
5 INT227906 IL10 Regulation of Gene_expression of IL1B 1 0.07 0.57 0.38 87.04
6 INT227909 IL10 Regulation of Gene_expression of TNF 1 0.21 0.57 0.38 87.04
7 INT227928 Binding of MMRN1 and Lamb3 1 0.03 1.16 0.56 86.32
8 INT227911 Binding of VTN and MMRN1 1 0.01 1.16 0.56 85.36
9 INT170992 Binding of FN1 and MMRN1 3 0.01 2.13 0.73 85.36
10 INT227908 Binding of COL7A1 and MMRN1 1 0.00 1.11 0.53 85.36
11 INT227905 IL10 Positive_regulation of Gene_expression of TIMP1 1 0.01 0.48 0.22 83.20
12 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49 81.20
13 INT340298 Ea1 Positive_regulation of Ppargc1a 1 0.05 1.03 0.64 81.20
14 INT340301 Ea1 Positive_regulation of Gene_expression of ACOX1 1 0.01 0.72 0.4 80.40
15 INT227910 TNF Positive_regulation of Gene_expression of IL10 1 0.22 0.68 0.29 78.72
16 INT227907 TNFRSF1B Regulation of TNF 1 0.01 0.41 0.36 77.64
17 INT227904 TNFRSF1A Regulation of TNF 1 0.01 0.41 0.36 77.64
18 INT333886 Binding of Lep and Positive_regulation of Gene_expression of Nos2 1 0.39 0.73 0.29 75.88
19 INT333887 Binding of Lep and Positive_regulation of Gene_expression of Il1 1 0.17 0.73 0.29 75.88
20 INT152541 CBX1 Negative_regulation of Gene_expression of PTGES 1 0.15 0.3 0 75.68
21 INT152542 ACF Negative_regulation of Gene_expression of PTGES 1 0.23 0.3 0 75.36
22 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65 75.00
23 INT168185 Binding of PLXNA2 and MRI1 1 0.25 0.78 1.08 75.00
24 INT333889 Lep Regulation of Col7a1 1 0.04 0.41 0.2 72.28
25 INT333888 Lep Regulation of Localization of GAG 1 0.68 0.38 0.19 67.48
26 INT352201 Negative_regulation of ALOX5 Negative_regulation of Cpox 1 0.02 0.89 0.81 60.08
27 INT165988 PTGER1 Positive_regulation of TNFSF11 1 0.05 0.13 0 50.00
28 INT165986 PTGER1 Regulation of Positive_regulation of TNFSF11 1 0.04 0.12 0 50.00
29 INT165985 PTGER1 Regulation of Positive_regulation of TNFRSF11B 1 0.03 0.12 0 50.00
30 INT165984 PTGER1 Regulation of Gene_expression of TNFRSF11B 1 0.04 0.16 0 50.00
31 INT165987 PTGER1 Regulation of Gene_expression of TNFSF11 1 0.06 0.16 0 50.00
32 INT152543 CBX1 Regulation of Gene_expression of RETNLB 1 0.00 0 0 37.56
33 INT152540 ACF Regulation of Gene_expression of RETNLB 1 0.00 0 0 37.24
34 INT340295 Nrf1 Regulation of Ppargc1a 1 0.25 0 0.24 36.80
35 INT326118 Binding of BMI1 and PCSK1 1 0.09 0 0 33.12
36 INT333885 Lep Positive_regulation of Il1 1 0.17 0.05 0.03 29.00
37 INT212662 KCNA1 Regulation of Localization of Cort 1 0.00 1.36 1.37 26.92
38 INT303966 Lep Regulation of Il1 2 0.09 0.41 0.1 25.36
39 INT212658 KCNA1 Positive_regulation of Cort 1 0.00 2.58 3.36 5.00
40 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85 5.00
41 INT194863 Binding of IL1R1 and IL1RN 5 0.09 2.23 1.64 5.00
42 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57 5.00
43 INT352196 Igkv12-66 Negative_regulation of Gm10404 1 0.00 1.62 1.34 5.00
44 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2 5.00
45 INT346986 Binding of SHC3 and PAG1 1 0.35 1.02 1.12 5.00
46 INT212661 KCNA1 Positive_regulation of Scort1 1 0.00 0.91 1.03 5.00
47 INT185417 Binding of ALOX5 and PLA2G2A 4 0.16 3.13 0.9 5.00
48 INT351323 Nts Regulation of Localization of Calca 1 0.01 0.6 0.85 5.00
49 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83 5.00
50 INT322201 Binding of OAP and SLC34A1 1 0.01 1.49 0.77 5.00
51 INT351322 Nts Regulation of Localization of Napa 1 0.01 0.56 0.77 5.00
52 INT270099 Negative_regulation of Binding of CPOX and PLA2G2A 1 0.01 0.51 0.59 5.00
53 INT270100 Negative_regulation of Binding of ALOX5 and PLA2G2A 1 0.01 0.51 0.59 5.00
54 INT270103 Binding of CPOX and PLA2G2A 1 0.01 0.5 0.58 5.00
55 INT270102 ALOX5 Negative_regulation of PLA2G2A 1 0.01 0.49 0.57 5.00
56 INT270101 CPOX Negative_regulation of PLA2G2A 1 0.01 0.48 0.56 5.00
57 INT212659 KCNA1 Regulation of Cort 1 0.00 0.41 0.49 5.00
58 INT340296 Ea1 Regulation of Gene_expression of Sirt1 1 0.08 0.15 0.46 5.00
59 INT340291 Ea1 Regulation of Gene_expression of Ins1 1 0.03 0.62 0.46 5.00
60 INT340292 Ea1 Positive_regulation of Ins1 1 0.04 0.6 0.43 5.00
61 INT351237 HRAS Regulation of CBL 1 0.00 0.48 0.4 5.00
62 INT209918 Positive_regulation of Nlrp3 Positive_regulation of Localization of Il1 1 0.42 1.06 0.4 5.00
63 INT340297 Ea1 Positive_regulation of Negative_regulation of Peg10 1 0.00 0 0.39 5.00
64 INT200469 Binding of COL7A1 and COMP 1 0.04 0.91 0.38 5.00
65 INT194865 Binding of SIGMAR1 and Positive_regulation of IL1B 1 0.01 0.62 0.35 5.00
66 INT194862 SIGMAR1 Positive_regulation of IL1B 1 0.01 0.62 0.35 5.00
67 INT194860 BMPR2 Positive_regulation of IL1B 1 0.01 0.61 0.34 5.00
68 INT194859 IL1B Positive_regulation of Gene_expression of MMP13 2 0.52 0.86 0.33 5.00
69 INT194858 Binding of IL1B and SIGMAR1 1 0.01 0.55 0.3 5.00
70 INT335821 MIR146A Regulation of Gene_expression of Il17a 1 0.05 0.75 0.24 5.00
71 INT333927 GLUL Positive_regulation of HSPA5 1 0.17 0.78 0.24 5.00
72 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19 5.00
73 INT217665 ADIPOQ Positive_regulation of INS 2 0.06 1.8 0.19 5.00
74 INT340299 Ea1 Regulation of Ppargc1a 1 0.03 0.41 0.16 5.00
75 INT333930 GLUL Positive_regulation of HRASLS 1 0.01 0.43 0.14 5.00
76 INT217667 LEP Negative_regulation of Localization of INS 1 0.15 1.18 0.14 5.00
77 INT217664 LEP Negative_regulation of INS 1 0.15 1.18 0.14 5.00
78 INT254643 Binding of Mapk8ip1 and Slc9a3r2 1 0.00 0.27 0.12 5.00
79 INT304813 Binding of MNX1 and RT1-CE1 1 0.00 0.34 0.1 5.00
80 INT269788 Binding of FN1 and TGFB1 1 0.00 0.29 0.1 5.00
81 INT335771 MIR155 Regulation of IRAK1 1 0.04 0.29 0.09 5.00
82 INT335772 MIR155 Regulation of SOCS1 1 0.01 0.29 0.09 5.00
83 INT217666 ADIPOQ Regulation of Gene_expression of INS 1 0.03 1.99 0.05 5.00
84 INT340293 Binding of Ins1 and Sirt1 1 0.25 1.25 0.05 5.00
85 INT313618 Binding of Acly and Pdgfb 1 0.00 0.18 0.03 5.00
86 INT354566 F2 Positive_regulation of PRNP 1 0.00 0.05 0 5.00
87 INT333926 Binding of PDIA3 and ERLEC1 1 0.02 0.18 0 5.00
88 INT333928 Binding of CALR and ESR1 1 0.09 0.09 0 5.00
89 INT333929 Binding of ESR1 and ERLEC1 1 0.01 0.09 0 5.00
90 INT333931 Binding of CALR and PDIA3 1 0.18 0.18 0 5.00
91 INT180836 Binding of CTD and NF1 1 0.15 0.2 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Knee Osteoarthritis. They are ordered first by their pain relevance and then by number of times they were reported in Knee Osteoarthritis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT138772 Binding of Koa 2 0.31 4.06 2.76 100.00
2 INT135234 Regulation of ETFDH 13 0.29 10.8 3.4 100.00
3 INT297414 Localization of Koa 1 0.20 3 2.08 100.00
4 INT297413 Gene_expression of Koa 2 0.22 1.88 1.37 100.00
5 INT63553 Binding of PAG1 14 0.48 12.51 14.76 100.00
6 INT245200 Protein_catabolism of Koa 2 0.29 1.69 0.93 100.00
7 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 100.00
8 INT155010 Positive_regulation of Gene_expression of IL17A 23 0.64 20.17 7.15 100.00
9 INT121752 Gene_expression of IL11 54 0.62 18.05 7.16 100.00
10 INT172179 Positive_regulation of Gene_expression of IL11 7 0.55 4.29 2.43 100.00
11 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 100.00
12 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 100.00
13 INT97016 Regulation of Binding of CALM1 4 0.39 0.79 2.09 100.00
14 INT323378 Positive_regulation of Koa 1 0.17 1.02 0.56 100.00
15 INT323377 Positive_regulation of Protein_catabolism of Koa 1 0.17 1.01 0.53 100.00
16 INT138773 Negative_regulation of Koa 2 0.37 0.28 0.13 100.00
17 INT238920 Positive_regulation of SLC9A3R2 44 0.50 27.86 10.51 99.98
18 INT23147 Negative_regulation of MRI1 26 0.38 14.33 8.96 99.98
19 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72 99.96
20 INT227925 Negative_regulation of Gene_expression of ITGB1 1 0.02 2.19 1.12 99.96
21 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 99.96
22 INT28020 Binding of Adipoq 10 0.36 11.49 0.77 99.96
23 INT318953 Positive_regulation of AA467197 1 0.22 0.17 0.08 99.96
24 INT133508 Positive_regulation of TKTL1 8 0.60 6.37 4.8 99.92
25 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83 99.90
26 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28 99.90
27 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 99.88
28 INT143952 Regulation of Gene_expression of MMP9 14 0.53 10.16 2.73 99.88
29 INT102680 Protein_catabolism of COL7A1 49 0.69 34.68 15.78 99.84
30 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 99.84
31 INT81399 Regulation of Vcam1 24 0.46 23.53 7.68 99.84
32 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01 99.84
33 INT57274 Positive_regulation of Gene_expression of COL7A1 50 0.69 24.19 4.72 99.84
34 INT103246 Positive_regulation of Protein_catabolism of COL7A1 8 0.34 8.67 3.03 99.84
35 INT122290 Regulation of Gene_expression of Vcam1 9 0.42 7.15 2.26 99.84
36 INT318952 Positive_regulation of Slc9a3r2 1 0.05 0.76 0.3 99.80
37 INT99058 Regulation of PAG1 18 0.45 21.62 18.5 99.80
38 INT70265 Regulation of MRI1 42 0.39 30.95 14.18 99.76
39 INT221000 Phosphorylation of COL2A1 1 0.19 0.18 0.12 99.76
40 INT183675 Negative_regulation of ETFDH 11 0.37 5.62 2.18 99.70
41 INT53021 Positive_regulation of COL2A1 29 0.55 27.75 3.47 99.70
42 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.64
43 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 99.64
44 INT70050 Negative_regulation of IL10 56 0.58 37.45 12.39 99.64
45 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12 99.60
46 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 99.60
47 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46 99.60
48 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 99.60
49 INT77855 Gene_expression of Pain1 55 0.75 67.42 54.1 99.60
50 INT81417 Gene_expression of PAG1 94 0.58 90.85 92.79 99.60
51 INT240060 Binding of NME8 1 0.42 3.85 1.69 99.56
52 INT240059 Binding of RHOB 7 0.48 3.96 1.59 99.56
53 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 99.56
54 INT194957 Binding of ASPN 5 0.27 2.95 1.09 99.56
55 INT14559 Gene_expression of Igf1 254 0.78 112 34.17 99.54
56 INT82828 Positive_regulation of COMP 45 0.61 35.12 6.2 99.48
57 INT171253 Positive_regulation of BMI1 23 0.53 39.41 11.23 99.46
58 INT27135 Gene_expression of SAFB 9 0.68 0.96 0.79 99.32
59 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86 99.32
60 INT10706 Regulation of Il6 150 0.62 93.23 62.34 99.28
61 INT78901 Localization of CCL5 67 0.78 40.79 20.59 99.24
62 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 99.20
63 INT125477 Gene_expression of HHIP 91 0.78 31.18 12.57 99.16
64 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95 99.16
65 INT319768 Binding of FRZB 1 0.34 2.35 1.58 99.04
66 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 99.00
67 INT104915 Negative_regulation of Bmd3 3 0.10 1.98 0.75 98.96
68 INT165228 Binding of BMI1 13 0.47 25.36 7.97 98.90
69 INT32165 Binding of CALM1 92 0.48 24.19 29.57 98.88
70 INT97307 Binding of NXT1 12 0.06 5.67 2.32 98.68
71 INT20129 Regulation of Il1 53 0.53 44.14 19.89 98.64
72 INT91338 Binding of Lep 31 0.48 26.86 5.39 98.64
73 INT17886 Negative_regulation of Il1 95 0.57 70.91 31.25 98.60
74 INT143180 Regulation of TKTL1 1 0.21 0.36 0.31 98.60
75 INT8713 Regulation of Tac1 56 0.60 25.29 45.94 98.56
76 INT65889 Gene_expression of RETNLB 73 0.34 60.98 38.3 98.52
77 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 98.50
78 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 98.50
79 INT180497 Binding of MRI1 45 0.42 28.35 14.77 98.48
80 INT155039 Gene_expression of ADAMTS5 23 0.67 7.85 3.22 98.48
81 INT171251 Regulation of BMI1 8 0.20 10.46 2.01 98.46
82 INT62944 Regulation of Icam1 33 0.47 23.52 7.94 98.32
83 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 98.32
84 INT112081 Negative_regulation of Vsig2 9 0.34 2.37 1.69 98.32
85 INT92632 Gene_expression of Vsig2 48 0.50 19.93 3.04 98.32
86 INT165871 Negative_regulation of Gene_expression of Vsig2 2 0.24 0.83 0.32 98.32
87 INT130867 Gene_expression of TNFSF11 106 0.77 45.15 10.34 98.32
88 INT135181 Regulation of Gene_expression of TNFSF11 5 0.61 6.98 1.27 98.32
89 INT77670 Positive_regulation of ACLY 24 0.49 21.68 3.12 98.32
90 INT107541 Positive_regulation of MSD 7 0.43 5.41 1.45 98.28
91 INT81929 Negative_regulation of Gene_expression of IL10 41 0.57 27.99 9.87 98.24
92 INT178828 Regulation of Pain1 12 0.14 16.1 15.64 98.20
93 INT227921 Regulation of Binding of MMRN1 1 0.02 1.65 0.94 98.14
94 INT127208 Regulation of Gpx1 3 0.48 1.34 0.38 98.12
95 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 98.04
96 INT304812 Binding of OA10 1 0.06 0.72 0.36 98.02
97 INT18884 Regulation of RYBP 25 0.38 11.43 23.2 97.92
98 INT89484 Gene_expression of TNFRSF11B 119 0.76 53.57 19.67 97.92
99 INT165989 Regulation of Gene_expression of TNFRSF11B 4 0.53 2.58 1.1 97.92
100 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82 97.80
101 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 97.80
102 INT62869 Negative_regulation of REG3A 4 0.57 4.31 0.82 97.80
103 INT91432 Binding of MMRN1 23 0.36 9.79 2.95 97.78
104 INT44637 Positive_regulation of Slc9a3r2 18 0.55 7.27 1.72 97.72
105 INT172177 Protein_catabolism of INCENP 18 0.37 6.34 2.91 97.60
106 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97 97.44
107 INT11354 Regulation of Gene_expression of SERPINE1 11 0.61 8.66 4.42 97.44
108 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 97.42
109 INT6516 Positive_regulation of BGLAP 45 0.67 26.61 9.9 97.24
110 INT51106 Gene_expression of PPP1R1A 5 0.67 1.76 1.99 97.16
111 INT66443 Regulation of Gene_expression of PPP1R1A 2 0.35 0.35 0.57 97.16
112 INT11708 Regulation of SCT 12 0.44 2.29 4.07 97.04
113 INT125384 Positive_regulation of Pain1 23 0.49 17.1 14.83 96.88
114 INT4241 Regulation of CALCA 87 0.62 28.19 55.29 96.84
115 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 96.76
116 INT126751 Regulation of Gene_expression of IL10 16 0.44 10.84 5.22 96.76
117 INT240061 Binding of LRCH1 2 0.44 1.05 0.37 96.68
118 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09 96.64
119 INT11359 Gene_expression of PLAU 84 0.76 49.54 12.31 96.48
120 INT11364 Regulation of Gene_expression of PLAU 4 0.58 3.23 1.92 96.48
121 INT240058 Gene_expression of RHOB 2 0.55 4.29 1.84 96.44
122 INT111890 Binding of MSD 26 0.41 8.05 1.71 96.44
123 INT9660 Regulation of TNF 363 0.62 312.94 139.99 96.00
124 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 96.00
125 INT102987 Regulation of MMP3 23 0.60 9.35 9.54 96.00
126 INT130731 Protein_catabolism of COL2A1 47 0.96 21.86 9.28 95.96
127 INT130729 Negative_regulation of Protein_catabolism of COL2A1 15 0.42 7.59 3.35 95.96
128 INT323379 Gene_expression of SP9 1 0.43 1.11 0.46 95.68
129 INT329740 Transcription of TKTL1 1 0.27 0.26 0.16 95.64
130 INT73497 Regulation of IL10 33 0.45 22.6 9.19 95.48
131 INT76573 Negative_regulation of Vcam1 26 0.58 24.36 9.84 95.40
132 INT79298 Localization of NXT1 9 0.60 4.9 3.42 95.36
133 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47 95.36
134 INT7439 Positive_regulation of CFP 52 0.67 19.97 17.87 95.24
135 INT142162 Binding of IL10 30 0.37 21.9 4.84 95.24
136 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 95.04
137 INT11180 Binding of RYBP 52 0.46 13.86 42.53 95.04
138 INT71727 Negative_regulation of Icam1 25 0.45 17.76 5.73 94.96
139 INT92716 Negative_regulation of PAG1 6 0.51 5.82 6.32 94.88
140 INT293636 Negative_regulation of Soa 1 0.23 0.6 0.31 94.68
141 INT171252 Gene_expression of BMI1 21 0.70 26.98 4.11 94.64
142 INT19131 Localization of CYP27A1 14 0.80 8.19 2.15 94.64
143 INT286596 Positive_regulation of Positive_regulation of SLC9A3R2 2 0.50 3.37 1.07 94.44
144 INT97768 Positive_regulation of Gene_expression of PLG 5 0.49 2.49 0.89 94.40
145 INT188444 Binding of SQSTM1 5 0.44 4.69 0.54 94.40
146 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 94.32
147 INT73309 Regulation of Negative_regulation of PTGS2 14 0.44 9.55 4.5 94.32
148 INT61684 Localization of COL1A2 20 0.73 9.31 2.26 94.24
149 INT39867 Binding of Col2a1 9 0.35 7.65 3.18 94.24
150 INT65391 Positive_regulation of Vsig2 13 0.32 5.71 1.49 94.20
151 INT2144 Localization of COL7A1 36 0.74 20.92 4.67 94.20
152 INT12891 Negative_regulation of MMP3 41 0.58 17.99 15.06 94.20
153 INT27437 Negative_regulation of Comp 5 0.24 2.8 2.15 94.16
154 INT151309 Positive_regulation of Positive_regulation of MMP3 5 0.60 2.62 2.5 93.96
155 INT26314 Positive_regulation of MMP3 48 0.67 22.14 16.17 93.96
156 INT4561 Gene_expression of PLG 32 0.75 17.59 6.21 93.84
157 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 93.80
158 INT73836 Regulation of Comp 4 0.19 4.2 2.79 93.76
159 INT50972 Negative_regulation of Ntrk1 39 0.51 32.22 17.29 93.76
160 INT66960 Negative_regulation of ACACA 4 0.57 1.21 3.59 93.68
161 INT145256 Binding of Acly 2 0.07 1.17 0.27 93.68
162 INT187133 Protein_catabolism of TIMP1 19 0.73 11.3 5.51 93.64
163 INT217686 Positive_regulation of Negative_regulation of SHBG 1 0.26 1.97 0.33 93.44
164 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 93.40
165 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 93.40
166 INT173852 Protein_catabolism of ACAN 3 0.64 1.65 1.01 93.28
167 INT4297 Negative_regulation of CFP 21 0.42 12.7 10.29 93.20
168 INT37245 Protein_catabolism of IL4I1 2 0.34 0.6 0.57 92.92
169 INT318950 Gene_expression of Slc9a3r2 2 0.09 0.2 0.1 92.88
170 INT8340 Negative_regulation of SHBG 49 0.57 35.96 4.73 92.68
171 INT318945 Gene_expression of AA467197 1 0.30 1.44 0.79 92.68
172 INT118095 Regulation of COMP 7 0.43 9.69 3.33 92.64
173 INT153776 Positive_regulation of IL17A 42 0.64 34.58 14.82 92.40
174 INT25610 Positive_regulation of Gene_expression of Il1 136 0.67 104.43 43.86 92.24
175 INT293637 Gene_expression of Soa 1 0.37 0.59 0.3 92.08
176 INT122051 Negative_regulation of ROM1 17 0.48 9.11 3.38 92.00
177 INT87863 Positive_regulation of IL18 40 0.69 34.08 9.53 91.96
178 INT19626 Regulation of Xdh 4 0.22 2.69 1.7 91.72
179 INT127647 Regulation of Wnt7a 3 0.07 1.28 1.01 91.56
180 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 91.48
181 INT156926 Protein_catabolism of Vsig2 5 0.57 2.01 0.64 91.04
182 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92 90.96
183 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 90.64
184 INT10506 Gene_expression of PTAFR 86 0.76 37.57 28.58 90.64
185 INT127649 Regulation of Ifih1 6 0.23 4.21 1.92 90.36
186 INT227522 Regulation of Hspa9 4 0.39 1.85 0.66 90.00
187 INT61500 Binding of FN1 39 0.48 27.33 3.13 89.56
188 INT286597 Localization of SLC9A3R2 3 0.54 6.71 1.05 89.20
189 INT97145 Positive_regulation of TBK1 14 0.12 15.32 5.43 89.12
190 INT79261 Positive_regulation of Gene_expression of COL1A1 24 0.36 7.49 2.45 88.72
191 INT6852 Localization of TNF 883 0.81 705.95 270.84 88.64
192 INT163581 Localization of Lep 27 0.79 18.99 4.08 88.64
193 INT335799 Positive_regulation of RA11 1 0.08 3.21 1.13 88.24
194 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15 88.16
195 INT119001 Regulation of ACLY 5 0.44 4.83 0.36 88.08
196 INT53525 Positive_regulation of NXT1 11 0.35 4.81 2.41 87.60
197 INT82829 Gene_expression of COMP 104 0.78 57 9.81 87.60
198 INT335794 Positive_regulation of RA10 1 0.08 1.6 0.52 87.52
199 INT263523 Regulation of Binding of BMI1 1 0.34 3.01 1.3 87.48
200 INT351199 Gene_expression of Ptpn9 1 0.20 1 0.89 87.28
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