D:Labor Pain

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Disease Term
Synonyms OBSTETRIC PAIN, Pain Labor, Pain Obstetric
Documents 475
Hot Single Events 63
Hot Interactions 5

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Labor Pain. They are ordered first by their relevance to Labor Pain and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT148102 AGT Positive_regulation of Gene_expression of STK24 1 0.37 0.96 0.1 96.88
2 INT148103 MAPK8 Positive_regulation of STK24 1 0.47 1.82 0.17 87.20
3 INT324068 Binding of GCH1 and SNRNP70 1 0.01 28.19 40.6 86.72
4 INT41512 Oxt Regulation of Cga 1 0.01 0.09 0.09 85.00
5 INT41514 Oxt Regulation of AFP 1 0.16 0.09 0.09 85.00
6 INT154237 Binding of CYP2D6 and Ugt2b7 1 0.41 0.75 1 63.08
7 INT154236 Binding of TBX3 and Ugt2b7 1 0.41 0.74 1 62.80
8 INT324067 Regulation of Binding of GCH1 and SNRNP70 1 0.01 0.95 1.67 5.00
9 INT225690 KNG1 Positive_regulation of TRPV1 1 0.42 0.7 0.83 5.00
10 INT225691 TRPV1 Positive_regulation of Localization of CALCA 1 0.18 0.7 0.83 5.00
11 INT244338 Slc12a7 Positive_regulation of SERPINH1 1 0.00 0.26 0.13 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Labor Pain. They are ordered first by their pain relevance and then by number of times they were reported in Labor Pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT128 Negative_regulation of Localization of OXTR 7 0.59 2.92 2.86 100.00
2 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 100.00
3 INT462 Regulation of Pomc 157 0.62 41.67 67.27 99.98
4 INT120775 Gene_expression of Sp6 7 0.66 0.98 0.81 99.84
5 INT120774 Regulation of Gene_expression of Sp6 3 0.39 0.3 0.78 99.84
6 INT677 Positive_regulation of CST3 20 0.67 17.47 6 99.74
7 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07 99.68
8 INT29555 Positive_regulation of CALM1 58 0.69 14.09 17.37 99.56
9 INT129 Localization of OXTR 51 0.80 11.08 15.36 99.14
10 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 99.04
11 INT738 Regulation of POMC 459 0.62 111.19 243.74 98.96
12 INT1197 Negative_regulation of Localization of POMC 109 0.59 28.29 48.02 98.76
13 INT443 Localization of POMC 1020 0.81 284.52 443.17 98.76
14 INT52106 Negative_regulation of Localization of IL8 57 0.52 22.81 20.8 98.68
15 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71 98.68
16 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 98.44
17 INT12339 Localization of IL8 437 0.81 251.87 117.39 98.16
18 INT145459 Negative_regulation of Transcription of Osm 1 0.06 1.23 1.38 97.60
19 INT145458 Transcription of Osm 1 0.08 1.22 1.37 97.16
20 INT148104 Gene_expression of STK24 1 0.77 2.85 0.28 96.88
21 INT148105 Positive_regulation of Gene_expression of STK24 1 0.69 2.86 0.28 96.88
22 INT3117 Regulation of Oxt 103 0.61 17.93 32.28 96.60
23 INT927 Gene_expression of Oxt 184 0.78 44.71 35.79 96.48
24 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 96.36
25 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 96.36
26 INT105021 Binding of GOPC 187 0.40 60.39 20.38 95.96
27 INT398 Localization of AGT 45 0.78 16.97 11.54 95.60
28 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 95.32
29 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 94.44
30 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 94.08
31 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 93.56
32 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 92.52
33 INT42469 Regulation of LNPEP 9 0.60 0.46 0.83 92.08
34 INT8580 Gene_expression of ELANE 132 0.75 62.98 21.79 91.92
35 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 91.76
36 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 91.76
37 INT39330 Negative_regulation of Negative_regulation of Mthfs 2 0.26 0.82 0.96 91.76
38 INT45855 Regulation of Negative_regulation of Mthfs 2 0.44 0.23 0.44 91.76
39 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 91.52
40 INT5069 Negative_regulation of Mthfs 69 0.57 22.54 31.36 91.08
41 INT30849 Gene_expression of Sle1a 1 0.00 0.73 0.66 90.84
42 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 90.80
43 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 90.24
44 INT937 Positive_regulation of Oxt 195 0.70 37.82 49.3 89.60
45 INT30851 Gene_expression of NRG1 8 0.67 4.64 1.12 89.28
46 INT21650 Regulation of OXTR 29 0.61 5.99 4.91 88.40
47 INT49436 Binding of TRPV1 145 0.48 38.35 55.08 87.68
48 INT129161 Binding of TRPM8 7 0.48 1.32 2.48 87.68
49 INT341684 Gene_expression of C5orf38 1 0.38 0.18 2.67 87.20
50 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79 86.80
51 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 85.60
52 INT30850 Gene_expression of MORF4 3 0.65 1.08 0.78 85.12
53 INT11479 Positive_regulation of KCNMA1 30 0.68 10.07 10.82 84.88
54 INT11485 Localization of KCNMA1 7 0.09 1.81 2.6 84.88
55 INT11487 Positive_regulation of Localization of KCNMA1 4 0.06 1.5 2.31 84.88
56 INT14501 Gene_expression of CST3 28 0.75 25.77 5.16 84.48
57 INT14500 Positive_regulation of Gene_expression of CST3 9 0.67 7.46 1.87 84.48
58 INT679 Negative_regulation of CST3 7 0.57 4.63 1.22 84.48
59 INT17511 Negative_regulation of PRTN3 19 0.41 12 3.3 83.52
60 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 82.72
61 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 81.32
62 INT48222 Positive_regulation of Localization of IL8 123 0.59 78.04 37.2 81.32
63 INT52107 Transcription of IL8 63 0.72 41.66 16.06 80.92
64 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8 77.68
65 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 75.52
66 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 75.52
67 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 75.28
68 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 75.00
69 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 75.00
70 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 75.00
71 INT1931 Positive_regulation of Gene_expression of POMC 116 0.70 37.26 38.67 75.00
72 INT956 Negative_regulation of PRL 94 0.59 42.72 23.01 75.00
73 INT2005 Positive_regulation of Gene_expression of PRL 55 0.70 21.4 13.44 75.00
74 INT952 Negative_regulation of GHRH 57 0.56 25.3 10.34 75.00
75 INT954 Positive_regulation of Gene_expression of GHRH 18 0.50 7.6 1.63 75.00
76 INT25432 Negative_regulation of Gene_expression of GHRH 6 0.37 2.9 1.12 75.00
77 INT6042 Binding of Oprm1 248 0.48 31.77 154.34 70.72
78 INT62944 Regulation of Icam1 33 0.47 23.52 7.94 70.52
79 INT41513 Positive_regulation of Regulation of CNDP1 1 0.00 0.07 0.07 70.28
80 INT3958 Regulation of CNDP1 5 0.35 0.86 0.78 69.16
81 INT117611 Gene_expression of CD6 2 0.15 0.68 0.61 68.72
82 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 63.84
83 INT9377 Positive_regulation of Positive_regulation of TRPV1 43 0.70 15.81 24.47 56.80
84 INT3579 Localization of Oxt 555 0.81 43.35 292.44 55.84
85 INT124684 Positive_regulation of Gene_expression of Sp6 1 0.49 0 0 50.00
86 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43 47.76
87 INT7469 Positive_regulation of Gene_expression of Oxt 18 0.59 4.7 14.36 47.76
88 INT5941 Gene_expression of Oxt 164 0.76 22.63 65.47 47.36
89 INT42459 Positive_regulation of Gene_expression of Pag1 19 0.25 13.49 12.22 46.36
90 INT1351 Gene_expression of Pag1 131 0.57 89.48 98.76 45.76
91 INT130 Negative_regulation of OXTR 19 0.43 4.63 4.96 39.44
92 INT51922 Localization of Cpox 24 0.68 12.05 8.59 34.64
93 INT84925 Transcription of NGF 11 0.65 4.13 3.65 34.56
94 INT79149 Gene_expression of CSE 26 0.58 11.76 14.16 25.00
95 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 23.64
96 INT81796 Binding of AGRP 62 0.36 37.19 5.3 8.04
97 INT626 Localization of CALCA 289 0.81 125.39 221.15 5.00
98 INT397 Localization of SST 232 0.81 58.05 101.19 5.00
99 INT5587 Regulation of Fos 191 0.62 40.81 99.7 5.00
100 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
101 INT2893 Localization of Oxt 219 0.80 28.96 79.43 5.00
102 INT442 Localization of PDYN 99 0.81 11.87 72.75 5.00
103 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
104 INT9383 Localization of TRPV1 98 0.81 33.23 46.24 5.00
105 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24 5.00
106 INT4862 Localization of PENK 62 0.81 11.57 40.28 5.00
107 INT7692 Positive_regulation of PENK 71 0.70 20.34 32.54 5.00
108 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
109 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 5.00
110 INT77902 Negative_regulation of Positive_regulation of TRPV1 30 0.59 9.36 19.2 5.00
111 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15 5.00
112 INT17974 Positive_regulation of Localization of Oxt 34 0.69 4.45 12.9 5.00
113 INT31341 Positive_regulation of CSE 15 0.60 11.57 12.29 5.00
114 INT36287 Binding of CD4 96 0.47 58.93 11.88 5.00
115 INT7132 Localization of NPPA 53 0.81 19.79 10.86 5.00
116 INT1708 Gene_expression of OXTR 56 0.78 6.92 10.69 5.00
117 INT17592 Positive_regulation of Regulation of Fos 21 0.67 3.54 10.07 5.00
118 INT17233 Positive_regulation of Localization of PDYN 9 0.69 2.84 10.06 5.00
119 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 5.00
120 INT20205 Binding of IgG 108 0.46 66.68 8.57 5.00
121 INT621 Positive_regulation of SERPINH1 19 0.57 21.52 8.44 5.00
122 INT6133 Negative_regulation of Serpinc1 56 0.58 42.8 8.35 5.00
123 INT6957 Positive_regulation of OXTR 38 0.70 6.55 7.81 5.00
124 INT152347 Binding of GCH1 8 0.37 6.13 7.36 5.00
125 INT67822 Binding of SERPINH1 17 0.36 19.05 7.24 5.00
126 INT154115 Positive_regulation of Localization of PENK 5 0.49 3.15 6.93 5.00
127 INT163776 Regulation of GCH1 7 0.27 4.58 6.16 5.00
128 INT68661 Positive_regulation of NTSR1 11 0.69 9.6 5.91 5.00
129 INT100593 Gene_expression of UBAP1 8 0.65 13.81 5.74 5.00
130 INT71760 Binding of CSE 9 0.48 2.84 5.42 5.00
131 INT46121 Negative_regulation of SERPINH1 14 0.38 10.84 4.41 5.00
132 INT288550 Localization of CSE 2 0.59 1.32 3.08 5.00
133 INT157904 Positive_regulation of Gene_expression of CSE 2 0.39 1.35 3.01 5.00
134 INT23352 Negative_regulation of A2M 10 0.33 8.35 2.16 5.00
135 INT18007 Positive_regulation of C6orf25 23 0.66 14.98 1.95 5.00
136 INT288551 Positive_regulation of Localization of CSE 2 0.39 1.27 1.59 5.00
137 INT216932 Positive_regulation of Negative_regulation of Il6 3 0.38 4.88 1.55 5.00
138 INT341682 Positive_regulation of C5orf38 1 0.28 0.3 1.53 5.00
139 INT341683 Binding of C5orf38 1 0.21 0.09 1.22 5.00
140 INT66618 Gene_expression of PNMA2 3 0.29 1.24 0.97 5.00
141 INT81795 Negative_regulation of AGRP 23 0.41 10.93 0.87 5.00
142 INT70027 Positive_regulation of Gene_expression of C6orf25 10 0.62 7.21 0.83 5.00
143 INT23348 Negative_regulation of Serpinf2 8 0.38 3.02 0.65 5.00
144 INT173092 Regulation of BAI1 3 0.24 3.16 0.44 5.00
145 INT185370 Gene_expression of ANC 28 0.65 13.28 0.4 5.00
146 INT258991 Gene_expression of Emb 2 0.43 2.55 0.23 5.00
147 INT258990 Localization of Emb 1 0.21 0.98 0.21 5.00
148 INT258989 Binding of Emb 1 0.10 0.98 0.21 5.00
149 INT241867 Positive_regulation of A1bg 1 0.12 0.33 0.03 5.00
150 INT185372 Negative_regulation of ANC 6 0.26 1.52 0.03 5.00
151 INT241868 Binding of A1bg 1 0.08 0.33 0.03 5.00
152 INT239065 Localization of ANC 3 0.46 0.77 0 5.00
153 INT257384 Positive_regulation of Positive_regulation of C6orf25 2 0.14 2.17 0 5.00
154 INT231623 Positive_regulation of SHE 6 0.44 1.04 0 5.00
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