D:Lactic Acidosis

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Disease Term
Synonyms Acidosis Lactic, Lactacidosis
Documents 382
Hot Single Events 99
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Lactic Acidosis. They are ordered first by their relevance to Lactic Acidosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT233304 Binding of SRY and SLC22A8 1 0.34 0.93 0 87.64
2 INT127155 MAA Negative_regulation of Uqcrc2 1 0.00 0.5 0.08 82.08
3 INT203009 Binding of Cpb1 and Dob2 1 0.02 0.77 0 78.88
4 INT127156 HSD17B10 Regulation of Acaa2 1 0.02 0 0.12 37.88
5 INT258492 Binding of Ins1 and Cdipt 1 0.00 0.92 0 29.84
6 INT269501 Nos1 Regulation of Lta 1 0.28 0.26 0.05 18.96
7 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3 5.00
8 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92 5.00
9 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9 5.00
10 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55 5.00
11 INT208980 Binding of Ca2 and Trpv1 4 0.32 0.67 1.55 5.00
12 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53 5.00
13 INT121226 Ngf Regulation of Gene_expression of Trpv1 2 0.62 0.7 1.44 5.00
14 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38 5.00
15 INT182096 Positive_regulation of Binding of Il6 and Il1 2 0.09 4.26 1.31 5.00
16 INT285185 Binding of Ca2 and Cd2 1 0.25 0.24 1.21 5.00
17 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11 5.00
18 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
19 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98 5.00
20 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 5.00
21 INT262572 Ngf Positive_regulation of Mapk1 2 0.04 0.52 0.81 5.00
22 INT262564 Ngf Positive_regulation of Pik3r1 1 0.08 0.36 0.8 5.00
23 INT262579 Ngf Positive_regulation of Prkca 1 0.07 0.36 0.8 5.00
24 INT262582 F2rl1 Regulation of Positive_regulation of Prkca 1 0.03 0.58 0.78 5.00
25 INT262562 F2rl1 Regulation of Trpv1 1 0.12 0.58 0.77 5.00
26 INT262563 Negative_regulation of Pax3 Regulation of Calca 1 0.01 0.75 0.76 5.00
27 INT262569 Pax3 Regulation of Calca 1 0.00 0.75 0.76 5.00
28 INT262577 Localization of Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.05 0.92 0.75 5.00
29 INT262578 Prkaca Positive_regulation of Localization of Calca 1 0.03 0.71 0.75 5.00
30 INT262573 Par2 Regulation of Positive_regulation of Prkca 1 0.05 0.57 0.72 5.00
31 INT262580 Ngf Positive_regulation of Hspg2 1 0.03 0.35 0.72 5.00
32 INT262581 Prkca Positive_regulation of Phosphorylation of Trpv1 1 0.13 0.28 0.71 5.00
33 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71 5.00
34 INT262566 Par2 Regulation of Trpv1 1 0.20 0.57 0.71 5.00
35 INT262571 Phosphorylation of Trpv1 Positive_regulation of Localization of Calca 1 0.17 0.71 0.7 5.00
36 INT262570 Binding of Pax3 and Trpv1 1 0.02 1.05 0.67 5.00
37 INT262576 Binding of Calca and Trpv1 1 0.13 1.05 0.66 5.00
38 INT179203 NLRP1 Regulation of Gene_expression of TNF 1 0.31 1.73 0.6 5.00
39 INT252869 Binding of Trpv1 and Phax 2 0.01 0.18 0.6 5.00
40 INT182021 Binding of TNF and Il6 2 0.04 0.74 0.53 5.00
41 INT262565 Prkaca Regulation of Negative_regulation of Trpv1 1 0.05 0.21 0.5 5.00
42 INT262575 Trpv1 Positive_regulation of Prkca 1 0.13 0.17 0.44 5.00
43 INT320695 TNF Positive_regulation of Localization of Il1 1 0.05 1.38 0.44 5.00
44 INT182100 Positive_regulation of Binding of TNF and Il6 1 0.03 0.66 0.41 5.00
45 INT179201 NLRP1 Regulation of Gene_expression of IL10 1 0.06 0.77 0.36 5.00
46 INT353454 Binding of BRCA1 and IL17A 1 0.00 2.55 0.36 5.00
47 INT179202 NLRP1 Regulation of Gene_expression of IL6 1 0.07 0.77 0.36 5.00
48 INT250781 IRF6 Positive_regulation of AMIGO2 1 0.02 1.25 0.35 5.00
49 INT320694 C5 Regulation of Gene_expression of Il2 1 0.03 2.15 0.34 5.00
50 INT320692 C5 Regulation of Gene_expression of Il12a 1 0.03 2.15 0.34 5.00
51 INT320693 C5 Regulation of Gene_expression of Il6 1 0.04 2.15 0.34 5.00
52 INT320696 C5 Regulation of Gene_expression of TNF 1 0.34 2.15 0.34 5.00
53 INT353452 Binding of AGRP and BRCA1 1 0.00 3.89 0.34 5.00
54 INT320691 C5 Regulation of Gene_expression of Il1 1 0.06 2.15 0.34 5.00
55 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 5.00
56 INT353448 BRCA1 Positive_regulation of CCL2 1 0.01 1.37 0.26 5.00
57 INT353449 BRCA1 Positive_regulation of IL4 1 0.00 1.37 0.26 5.00
58 INT353455 BRCA1 Positive_regulation of IL13 1 0.00 1.37 0.26 5.00
59 INT179200 Binding of ICAM1 and IL8 1 0.03 1.02 0.25 5.00
60 INT188842 Accn3 Positive_regulation of Calca 1 0.08 0.46 0.25 5.00
61 INT250783 APC Negative_regulation of SERPINE1 1 0.06 0.86 0.23 5.00
62 INT250782 APC Negative_regulation of F2 1 0.00 0.86 0.23 5.00
63 INT250779 PROC Regulation of IRF6 Positive_regulation of AMIGO2 1 0.00 0.74 0.22 5.00
64 INT241822 Binding of CD4 and HIVEP1 3 0.01 2.73 0.21 5.00
65 INT182634 Binding of CCR5 and MIP 2 0.39 1.29 0.2 5.00
66 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 5.00
67 INT340447 Negative_regulation of IRF6 Positive_regulation of RELA 1 0.00 0.87 0.18 5.00
68 INT285183 Cd2 Regulation of Ca2 1 0.30 0.23 0.18 5.00
69 INT274386 Binding of CD4 and ERVW-1 1 0.05 3.07 0.18 5.00
70 INT340448 IRF6 Positive_regulation of RELA 1 0.00 0.86 0.17 5.00
71 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15 5.00
72 INT292749 Akt1 Positive_regulation of Ctnnd2 1 0.09 1.73 0.15 5.00
73 INT292748 Akt1 Negative_regulation of Positive_regulation of Casp3 1 0.01 1.81 0.15 5.00
74 INT327829 Aqp1 Regulation of Binding of Csf2 1 0.11 1 0.14 5.00
75 INT353451 Binding of BRCA1 and CRP 1 0.01 1.18 0.14 5.00
76 INT353453 Binding of BRCA1 and IL4 1 0.00 1.18 0.14 5.00
77 INT258016 AGTR1 Positive_regulation of EGFR 1 0.15 1.24 0.13 5.00
78 INT258014 Binding of ANGPT2 and RASGRP1 1 0.00 1.58 0.1 5.00
79 INT258018 Binding of AGT and RASGRP1 1 0.00 1.59 0.1 5.00
80 INT164925 GIP Positive_regulation of Localization of INS 2 0.59 0.86 0.09 5.00
81 INT182644 Binding of CXCR4 and Cxcr4 1 0.10 0.66 0.09 5.00
82 INT228333 Binding of IFNA1 and IRF9 2 0.04 0.53 0.09 5.00
83 INT300246 Binding of ABCB6 and HSR 1 0.11 1.86 0.08 5.00
84 INT147774 Binding of HLA-B and ABCB6 2 0.40 1.03 0.08 5.00
85 INT352579 CNTF Negative_regulation of Gene_expression of NPY 1 0.17 0.89 0.07 5.00
86 INT172382 AGT Positive_regulation of Localization of EDN1 1 0.03 0.34 0.07 5.00
87 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07 5.00
88 INT172381 AVP Positive_regulation of Localization of EDN1 1 0.01 0.34 0.07 5.00
89 INT353450 Binding of BRCA1 and VEGFA 1 0.01 0.82 0.05 5.00
90 INT258015 Binding of ANGPT2 and REN 1 0.01 0.59 0.05 5.00
91 INT285184 Negative_regulation of Atp2a2 Negative_regulation of Localization of Ca2 1 0.04 0.66 0.05 5.00
92 INT233303 Binding of CD4 and SRY 1 0.07 0.34 0.05 5.00
93 INT182098 Binding of IL8 and Il2 1 0.00 0 0.04 5.00
94 INT258012 ANGPT2 Positive_regulation of Binding of AGTR1 and ANGPT2 1 0.00 0.29 0.04 5.00
95 INT229371 Positive_regulation of Pparg Negative_regulation of Gene_expression of Edn1 1 0.01 0.92 0.04 5.00
96 INT181168 Binding of CD79A and TAPBP 1 0.10 0.7 0.04 5.00
97 INT182099 Binding of TNF and Il2 1 0.01 0 0.04 5.00
98 INT250780 IRF6 Positive_regulation of ASAP1 1 0.06 0.34 0.04 5.00
99 INT258020 Binding of AGTR1 and ANGPT2 1 0.03 0.29 0.04 5.00
100 INT182095 Binding of Il2 and Il6 1 0.01 0 0.04 5.00
101 INT212584 IFNA1 Regulation of Gene_expression of CD4 1 0.21 0.98 0.03 5.00
102 INT308540 CD4 Regulation of Localization of AGRP 1 0.39 0.85 0.03 5.00
103 INT269502 Lta Negative_regulation of Map2k1 1 0.17 0.48 0.03 5.00
104 INT269504 Lta Negative_regulation of Map2k1 Negative_regulation of Nos1 1 0.17 0.49 0.03 5.00
105 INT274384 AGRP Negative_regulation of HIVEP1 1 0.00 0.77 0.03 5.00
106 INT316101 Binding of HIST1H4PS1 and ANGPTL5 1 0.01 0.28 0 5.00
107 INT181169 TAPBP Negative_regulation of MALT1 1 0.00 0.48 0 5.00
108 INT315543 NARFL Regulation of Gene_expression of HIF1A 1 0.01 0.63 0 5.00
109 INT300244 Binding of HLA-B and HSR 1 0.08 0.95 0 5.00
110 INT181167 TAPBP Negative_regulation of CD79A 1 0.11 0.48 0 5.00
111 INT312956 Regulation of Binding of MOCS1 and MTTP 1 0.00 0.21 0 5.00
112 INT327830 Alms1 Positive_regulation of Aqp4 1 0.03 0.15 0 5.00
113 INT336607 Gopc Regulation of Phosphorylation of Mapk13 1 0.00 0.62 0 5.00
114 INT255024 DPP4 Negative_regulation of Protein_catabolism of GLP1R 1 0.14 0.78 0 5.00
115 INT315541 ACO1 Negative_regulation of Gene_expression of ALAS2 1 0.17 0.18 0 5.00
116 INT315534 Binding of ACO1 and ERN1 1 0.01 0.18 0 5.00
117 INT181165 TAPBP Regulation of Gene_expression of CD79A 1 0.07 0.35 0 5.00
118 INT274385 Binding of ABAT and CDIPT 1 0.00 1.21 0 5.00
119 INT312955 Binding of MOCS1 and MTTP 1 0.00 0.21 0 5.00
120 INT255021 DPP4 Negative_regulation of Protein_catabolism of GIP 1 0.32 0.78 0 5.00
121 INT255025 Positive_regulation of GLP1R Positive_regulation of Localization of INS 1 0.17 0.12 0 5.00
122 INT274387 Binding of POLA1 and IGSF9 1 0.01 0.58 0 5.00
123 INT269500 Lta Positive_regulation of Protein_catabolism of Nos1 1 0.29 0.65 0 5.00
124 INT315535 Binding of ABCB7 and FECH 1 0.28 0.7 0 5.00
125 INT315533 Negative_regulation of GLRX5 Negative_regulation of Gene_expression of ALAS2 1 0.38 1.06 0 5.00
126 INT255023 Negative_regulation of DPP4 Positive_regulation of GIP 1 0.35 0.27 0 5.00
127 INT269503 Lta Regulation of Nos1 1 0.44 1.3 0 5.00
128 INT315532 Binding of NFS1 and ISCU 1 0.19 0.37 0 5.00
129 INT336606 Binding of Mapk8 and Map2k1 1 0.09 0.72 0 5.00
130 INT315538 Negative_regulation of GLRX5 Negative_regulation of Gene_expression of SLC40A1 1 0.25 1.14 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Lactic Acidosis. They are ordered first by their pain relevance and then by number of times they were reported in Lactic Acidosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT102696 Binding of MRP63 4 0.46 3.68 0.27 100.00
2 INT155218 Binding of ABCB6 18 0.35 13.93 2.25 99.96
3 INT44608 Gene_expression of C2 45 0.75 15.84 5.05 99.90
4 INT99327 Negative_regulation of PNKD 3 0.57 1.24 0.56 99.08
5 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76 99.04
6 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 98.84
7 INT284528 Negative_regulation of POLG2 2 0.17 2.19 0.33 98.72
8 INT812 Localization of INS 1026 0.81 515.6 145.31 98.56
9 INT156132 Gene_expression of Aqp9 26 0.49 14.33 3.48 98.48
10 INT262487 Positive_regulation of Gene_expression of Aqp9 6 0.32 5.29 0.24 98.48
11 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98 98.40
12 INT117720 Negative_regulation of Gene_expression of Akt1 11 0.37 2.33 3.08 98.40
13 INT292743 Negative_regulation of Binding of Bcl2 1 0.05 1.97 0.24 98.40
14 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34 98.20
15 INT97452 Positive_regulation of MOCS1 20 0.39 11.4 2.59 98.16
16 INT212594 Positive_regulation of Phosphorylation of polymerase 1 0.01 0.83 0 98.04
17 INT345457 Binding of Rer1 1 0.03 0.62 0.06 97.92
18 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39 97.90
19 INT169582 Phosphorylation of POLG 2 0.54 1.98 0.18 97.84
20 INT212586 Phosphorylation of polymerase 3 0.08 2.64 0 97.84
21 INT9813 Regulation of MAA 2 0.26 0.94 0.18 97.76
22 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37 97.58
23 INT134444 Positive_regulation of Binding of Bcl2 3 0.47 2.67 0.72 97.58
24 INT42317 Negative_regulation of Dlat 21 0.43 3.13 4.11 97.44
25 INT105884 Binding of Bcl2 19 0.35 15.67 3 97.14
26 INT5223 Negative_regulation of PDP1 8 0.41 1.74 0.37 96.40
27 INT98522 Gene_expression of Accn3 68 0.78 26.95 28.6 96.04
28 INT100195 Negative_regulation of SPANXB1 5 0.48 2.7 0.82 95.84
29 INT328566 Regulation of MTERF 1 0.37 1.05 0 95.60
30 INT57922 Gene_expression of CYP2C9 65 0.78 22.24 7.53 95.56
31 INT65880 Gene_expression of CYP2C8 25 0.77 9.49 1.92 95.56
32 INT99325 Positive_regulation of Pdha1 6 0.49 1.55 1.22 94.88
33 INT99326 Negative_regulation of Pdha1 2 0.42 0.85 0.84 94.88
34 INT115659 Gene_expression of ABCB6 29 0.75 13.59 1.43 94.64
35 INT17470 Negative_regulation of NDUFC1 3 0.05 3.43 0.75 94.44
36 INT152819 Negative_regulation of Pdk1 1 0.02 0.25 0.06 94.28
37 INT328570 Binding of MTERF 1 0.45 0.99 0 94.24
38 INT77515 Positive_regulation of ASIC3 12 0.67 3.67 4.19 94.04
39 INT172677 Gene_expression of SHE 65 0.59 25.86 3.85 94.04
40 INT345462 Localization of Rer1 1 0.05 0.35 0 93.88
41 INT174979 Phosphorylation of GOPC 45 0.51 10.11 2.28 92.84
42 INT152820 Positive_regulation of PDHX 1 0.02 0.26 0.06 92.16
43 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14 91.76
44 INT84495 Positive_regulation of Positive_regulation of Ephb1 85 0.70 46.12 54.11 91.76
45 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 91.64
46 INT10872 Regulation of Dob2 5 0.20 2.06 0.25 91.48
47 INT35407 Positive_regulation of C2 25 0.69 7.74 2.59 90.68
48 INT53447 Negative_regulation of DLD 17 0.54 12.9 2.48 90.44
49 INT137756 Regulation of Negative_regulation of DLD 1 0.02 0.09 0.09 90.44
50 INT267901 Regulation of Negative_regulation of AKR1A1 1 0.07 1.45 0.17 90.36
51 INT166482 Negative_regulation of AKR1A1 5 0.15 2.51 1.07 90.36
52 INT70253 Negative_regulation of Gene_expression of Ca2 29 0.49 16.31 2.69 90.00
53 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 89.68
54 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64 89.52
55 INT8534 Localization of Pax3 85 0.59 28.71 82.82 89.52
56 INT70916 Binding of Thim 13 0.02 8.35 1.72 89.04
57 INT13286 Gene_expression of Ca2 317 0.67 71.58 65.01 88.96
58 INT5008 Localization of Calca 204 0.81 80.35 125.16 88.96
59 INT113625 Positive_regulation of Gene_expression of Ca2 47 0.50 9.82 14.07 88.96
60 INT17246 Negative_regulation of POLG 16 0.56 9.69 0.79 88.44
61 INT9900 Positive_regulation of Vwf 80 0.69 51.85 18.13 88.32
62 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51 87.92
63 INT111277 Negative_regulation of Gene_expression of C2 7 0.42 2.44 1.2 87.60
64 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67 87.08
65 INT36000 Gene_expression of TNFRSF25 4 0.58 2.94 0.35 86.88
66 INT108963 Positive_regulation of Gene_expression of TNFRSF25 3 0.42 2.24 0.27 86.88
67 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 86.68
68 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 86.68
69 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21 86.52
70 INT50446 Binding of MRGPRF 3 0.31 3.05 0.08 86.08
71 INT25585 Positive_regulation of DNAH8 39 0.70 17.96 7.85 85.84
72 INT188634 Positive_regulation of Sig 6 0.41 8.76 0.04 85.84
73 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 85.52
74 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 85.20
75 INT121338 Binding of MTUS1 5 0.07 3.41 0.16 85.00
76 INT4449 Positive_regulation of NA 179 0.55 40.26 37.82 84.96
77 INT59073 Gene_expression of Nae1 1 0.01 1.22 0.08 84.64
78 INT36287 Binding of CD4 96 0.47 58.93 11.88 84.44
79 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 84.16
80 INT292747 Positive_regulation of Gene_expression of Hspbp1 1 0.02 1.9 0.23 83.96
81 INT4679 Negative_regulation of RAPGEF5 55 0.57 47.51 4.55 83.72
82 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 83.64
83 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 83.56
84 INT292746 Gene_expression of Hspbp1 1 0.02 1.89 0.23 83.36
85 INT348636 Negative_regulation of OTC 1 0.43 3.39 0 82.60
86 INT10763 Localization of IL2 157 0.80 81.11 33.21 82.36
87 INT9055 Positive_regulation of Cog1 22 0.68 14.08 2.95 82.32
88 INT67635 Negative_regulation of Gnas 29 0.04 11.4 6.32 82.20
89 INT82155 Negative_regulation of Uqcrc2 5 0.21 1.28 0.82 82.08
90 INT49556 Gene_expression of NOLC1 11 0.49 29.44 1.07 81.88
91 INT4436 Gene_expression of ABCB7 7 0.65 9.26 0.93 81.88
92 INT2442 Localization of Mb 38 0.80 24.74 6.33 81.80
93 INT189633 Regulation of STK11 3 0.41 3.57 0.14 81.40
94 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76 80.96
95 INT130998 Regulation of PRKAB1 11 0.45 5.7 1.33 80.60
96 INT19511 Localization of Il6 212 0.81 118.17 67.67 80.48
97 INT107430 Localization of Cxcl2 8 0.66 7.05 1.2 80.48
98 INT181173 Binding of LDHD 1 0.05 0.77 0.03 80.40
99 INT320168 Regulation of APH1A 1 0.00 1.56 0.08 80.12
100 INT25070 Negative_regulation of Ndufs2 3 0.21 0.99 1.13 79.64
101 INT330862 Binding of Slc22a1 1 0.06 0.73 0 78.56
102 INT330860 Binding of Slc22a2 1 0.06 0.7 0 78.56
103 INT11365 Positive_regulation of Localization of Mb 5 0.38 3.78 1.54 78.56
104 INT62044 Binding of Lta 16 0.30 7.49 1.01 78.40
105 INT348634 Protein_catabolism of OTC 1 0.89 0.96 0 78.28
106 INT348635 Positive_regulation of Protein_catabolism of OTC 1 0.50 0.96 0 78.28
107 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 78.04
108 INT328574 Negative_regulation of MTERF 1 0.40 1.22 0.04 78.00
109 INT328565 Negative_regulation of Gene_expression of MTERF 1 0.54 1 0.04 78.00
110 INT17033 Positive_regulation of Trf 21 0.62 11.76 2.68 77.80
111 INT328567 Gene_expression of MTERF 1 0.72 1 0.04 77.68
112 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 77.40
113 INT279781 Gene_expression of MAVS 4 0.15 3.51 0.12 77.32
114 INT45075 Gene_expression of Sugt1 24 0.27 8.5 1.33 77.20
115 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 77.04
116 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 77.04
117 INT55342 Negative_regulation of Gene_expression of Ros1 49 0.37 31.62 8.93 76.68
118 INT2520 Negative_regulation of Ca2 271 0.57 72.13 83.71 76.56
119 INT45168 Negative_regulation of ASAP1 23 0.58 10.15 2.44 75.60
120 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43 75.16
121 INT26273 Negative_regulation of RYR1 18 0.43 7.64 3.11 75.00
122 INT860 Regulation of ALB 48 0.60 25.11 8.95 75.00
123 INT5095 Localization of Ghrh 185 0.81 28.09 62.08 75.00
124 INT54615 Gene_expression of GPER 25 0.75 8.23 2.27 75.00
125 INT54613 Negative_regulation of Renf2 1 0.04 0.34 0.07 75.00
126 INT220326 Negative_regulation of FECD7 4 0.05 2.79 0 74.12
127 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 73.96
128 INT13240 Gene_expression of TF 94 0.76 57.81 10.99 73.80
129 INT2531 Positive_regulation of Cebpz 166 0.00 43.08 38.86 73.60
130 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 73.44
131 INT148717 Binding of NR0B1 6 0.34 5.4 0.25 73.36
132 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 73.36
133 INT84284 Localization of Flvcr2 8 0.35 0.81 5.3 72.96
134 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 72.64
135 INT84527 Positive_regulation of Gene_expression of F3 16 0.49 15.83 2.85 72.64
136 INT20227 Regulation of Lta 11 0.35 6.16 1.91 72.32
137 INT20286 Positive_regulation of Dob2 16 0.24 5.04 0.41 72.08
138 INT59870 Gene_expression of F3 51 0.65 51.83 14.01 71.92
139 INT47741 Negative_regulation of Flvcr2 43 0.51 5.72 23.37 71.88
140 INT47503 Gene_expression of HPS1 12 0.58 7.96 2.7 71.40
141 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 71.32
142 INT46674 Positive_regulation of HBE1 4 0.40 2.25 0.42 71.08
143 INT102428 Binding of C2 17 0.32 5.12 1.58 70.96
144 INT64538 Binding of TNNI3 17 0.48 11.65 1.83 70.72
145 INT46721 Regulation of Csf2 26 0.45 20.4 6.18 70.60
146 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9 68.92
147 INT328572 Localization of AKAP9 1 0.62 1.14 0.05 68.88
148 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 67.84
149 INT148107 Binding of CDIPT 8 0.17 4.56 0.53 66.92
150 INT345461 Regulation of Regulation of Rer1 1 0.03 0.13 0 66.68
151 INT345463 Regulation of Rer1 1 0.03 0.25 0 65.88
152 INT22145 Binding of Sugt1 16 0.13 8.31 4.37 65.84
153 INT188756 Positive_regulation of AGRP 43 0.60 23.67 2.51 65.28
154 INT16090 Negative_regulation of Cpb1 4 0.36 0.51 0.14 64.56
155 INT174978 Gene_expression of HLA-V 1 0.01 0.24 0 64.00
156 INT105974 Positive_regulation of PRKAB1 43 0.67 23.47 4.16 64.00
157 INT81795 Negative_regulation of AGRP 23 0.41 10.93 0.87 63.84
158 INT109578 Positive_regulation of Accn3 16 0.70 9.09 10.05 63.72
159 INT81086 Positive_regulation of Accn1 8 0.65 7.51 4.62 63.72
160 INT79062 Gene_expression of B4GALNT1 42 0.14 18.89 6.98 63.40
161 INT2597 Negative_regulation of ACHE 82 0.59 46.36 8.62 63.24
162 INT127153 Negative_regulation of Ckmt1b 2 0.57 0.99 0.27 62.88
163 INT12485 Binding of DNAH8 17 0.48 4.24 2.54 62.80
164 INT172384 Positive_regulation of Positive_regulation of C2 2 0.14 0.3 0 62.20
165 INT5490 Binding of CA2 52 0.36 9.73 5.53 62.16
166 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 61.76
167 INT39553 Gene_expression of Hmgb1 50 0.75 51.18 12.21 61.76
168 INT111279 Positive_regulation of Gene_expression of C2 8 0.49 1.06 0.94 61.56
169 INT29393 Positive_regulation of APRT 18 0.67 5.28 2.13 61.40
170 INT258071 Positive_regulation of Negative_regulation of APRT 1 0.02 1.19 0.11 61.40
171 INT41545 Negative_regulation of APRT 8 0.57 2.99 2.88 61.08
172 INT134748 Positive_regulation of SV2A 7 0.46 2.89 0.82 61.04
173 INT32137 Regulation of Negative_regulation of Ca2 7 0.36 2.17 0.49 60.48
174 INT24020 Positive_regulation of HPS1 6 0.44 6.14 1.08 60.32
175 INT275449 Regulation of MFI2 8 0.44 6.49 1.7 59.08
176 INT141665 Gene_expression of AGRP 83 0.67 43.43 4.24 58.80
177 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38 58.48
178 INT14586 Gene_expression of Cpb1 23 0.58 6.18 1.99 58.16
179 INT36893 Negative_regulation of Coq10a 36 0.55 22.24 5.47 58.00
180 INT77281 Negative_regulation of HIVEP1 132 0.49 102.78 5.36 57.88
181 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6 57.76
182 INT174848 Gene_expression of ISCU 2 0.59 2.79 0.08 56.80
183 INT185407 Binding of PER1 13 0.42 9.32 2.6 56.72
184 INT80036 Positive_regulation of FAS 42 0.67 42.22 9.4 56.64
185 INT174977 Positive_regulation of TNFRSF25 7 0.38 5.63 0.32 56.64
186 INT221269 Binding of BRCA1 14 0.40 31.77 2.7 56.24
187 INT23257 Regulation of CRP 127 0.62 100.05 21.87 56.00
188 INT59951 Gene_expression of Dob2 8 0.52 1.65 0.1 55.76
189 INT172385 Regulation of Regulation of C2 1 0.14 0.27 0 55.68
190 INT130727 Regulation of C2 12 0.32 5.95 0.81 55.28
191 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23 54.64
192 INT23564 Negative_regulation of Car2 103 0.50 27.28 21.86 54.40
193 INT74051 Negative_regulation of Localization of Car2 27 0.38 9.58 5.1 54.40
194 INT14853 Negative_regulation of Tac1 80 0.59 30.87 45.06 54.16
195 INT6584 Negative_regulation of Pax3 31 0.39 14.64 27.97 54.16
196 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 54.04
197 INT306112 Regulation of NDUFV1 1 0.02 1 0 53.76
198 INT28308 Localization of SLC17A5 10 0.73 6.77 0.7 53.68
199 INT17561 Localization of Car2 303 0.79 60.95 44.52 53.52
200 INT35745 Negative_regulation of AGL 29 0.50 9.16 2.03 53.08
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