D:Latex Hypersensitivity

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pChart

Disease Term
Synonyms ALLERGIES LATEX, Allergies Rubber, ALLERGIES RUBBER LATEX, Allergy Latex, ALLERGY RUBBER, Allergy Rubber Latex, Hypersensitivities Latex, Hypersensitivity Latex, LATEX ALLERGIES, Latex Allergy, Latex Hypersensitivities
Documents 61
Hot Single Events 5
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Latex Hypersensitivity. They are ordered first by their relevance to Latex Hypersensitivity and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT87555 TPSAB1 Positive_regulation of IGHE 1 0.42 0.71 0.43 62.32
2 INT87556 TPSAB1 Positive_regulation of CD79A 1 0.40 0.7 0.42 62.32
3 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
4 INT334500 Binding of IGHE and SPARCL1 1 0.01 1.47 0.55 5.00
5 INT334499 Binding of AMELX and IL4 1 0.12 0.47 0.29 5.00
6 INT334497 Positive_regulation of IGHG3 Positive_regulation of IGHE 1 0.01 0.81 0.04 5.00
7 INT334496 IGHG3 Positive_regulation of IGHE 1 0.01 0.75 0.04 5.00
8 INT334498 Binding of IL13 and KLF1 1 0.00 0.63 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Latex Hypersensitivity. They are ordered first by their pain relevance and then by number of times they were reported in Latex Hypersensitivity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 97.68
2 INT62041 Negative_regulation of Gene_expression of IGHE 37 0.58 37.86 5.27 95.36
3 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 94.76
4 INT334504 Regulation of Transcription of IGHE 1 0.29 7.97 0.57 92.76
5 INT35866 Transcription of IGHE 9 0.60 12.83 2.19 92.40
6 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 79.24
7 INT65610 Negative_regulation of OR3A1 2 0.05 0.64 0.97 57.68
8 INT347182 Negative_regulation of TNFAIP3 3 0.23 5.6 0.84 57.68
9 INT182516 Negative_regulation of Negative_regulation of ACE 9 0.42 6.84 0.99 31.80
10 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 31.48
11 INT74423 Localization of IL10 91 0.80 61.6 22.95 12.96
12 INT69158 Localization of IL4 48 0.71 31.3 11.98 12.16
13 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
14 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
15 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 5.00
16 INT626 Localization of CALCA 289 0.81 125.39 221.15 5.00
17 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
18 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
19 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
20 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
21 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 5.00
22 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
23 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 5.00
24 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
25 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
26 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 5.00
27 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
28 INT7344 Gene_expression of TAC1 132 0.75 35.48 68.26 5.00
29 INT9489 Gene_expression of SFTPA1 112 0.66 55.38 66.45 5.00
30 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8 5.00
31 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 5.00
32 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
33 INT8835 Localization of SFTPA1 65 0.68 32.81 38.65 5.00
34 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 5.00
35 INT8837 Positive_regulation of TAC1 59 0.67 21.94 35.97 5.00
36 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
37 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 5.00
38 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7 5.00
39 INT8698 Localization of Nka1 50 0.78 5.8 27.67 5.00
40 INT14690 Localization of CSF2 124 0.80 85.17 27.26 5.00
41 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81 5.00
42 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
43 INT14884 Positive_regulation of Gene_expression of SFTPA1 32 0.25 20.37 26.09 5.00
44 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 5.00
45 INT8836 Positive_regulation of SFTPA1 36 0.47 28.37 23.59 5.00
46 INT8775 Binding of IGHE 167 0.48 102.61 23.54 5.00
47 INT8699 Gene_expression of Nka1 45 0.67 6.41 22.56 5.00
48 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52 5.00
49 INT23257 Regulation of CRP 127 0.62 100.05 21.87 5.00
50 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66 5.00
51 INT7336 Positive_regulation of VIP 60 0.70 24.2 19.62 5.00
52 INT13790 Binding of HTR1A 52 0.47 18.83 17.59 5.00
53 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33 5.00
54 INT10918 Gene_expression of ITGB2 93 0.76 71.8 16.34 5.00
55 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 5.00
56 INT4719 Positive_regulation of Nka1 27 0.67 4.16 15.42 5.00
57 INT132178 Binding of CD80 41 0.47 15.55 12.98 5.00
58 INT39244 Gene_expression of TMPO 137 0.77 14.55 11.83 5.00
59 INT15238 Positive_regulation of NPY 24 0.67 11.86 11.26 5.00
60 INT13240 Gene_expression of TF 94 0.76 57.81 10.99 5.00
61 INT48912 Localization of NOS1 52 0.77 24.14 10.92 5.00
62 INT60198 Binding of JUN 54 0.48 11.56 10.27 5.00
63 INT7411 Localization of FGFR3 40 0.78 4.77 10.24 5.00
64 INT10019 Binding of CD8A 57 0.36 31.49 10.08 5.00
65 INT73504 Binding of CD28 35 0.45 15.99 10.04 5.00
66 INT102525 Gene_expression of CCR3 24 0.71 16.19 10 5.00
67 INT5788 Gene_expression of IL2RA 60 0.75 40.67 9.98 5.00
68 INT3353 Localization of HLA-B 25 0.75 16.05 8.62 5.00
69 INT61628 Negative_regulation of Gene_expression of IL4 31 0.55 20.96 8.18 5.00
70 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89 5.00
71 INT2971 Regulation of IGHE 42 0.61 28.81 7.87 5.00
72 INT15165 Positive_regulation of Localization of Nka1 7 0.66 1.19 7.78 5.00
73 INT22275 Negative_regulation of TBXA2R 25 0.54 8.67 7.34 5.00
74 INT32709 Negative_regulation of Hbb 30 0.54 18.27 6.97 5.00
75 INT3757 Positive_regulation of Gene_expression of ALB 45 0.69 23.73 6.85 5.00
76 INT132822 Localization of IL13 26 0.67 22.85 6.66 5.00
77 INT69985 Positive_regulation of Negative_regulation of TNF 21 0.50 13.26 6.31 5.00
78 INT188844 Gene_expression of AES 44 0.58 33.94 5.85 5.00
79 INT135319 Positive_regulation of Positive_regulation of CRP 20 0.50 26.45 5.61 5.00
80 INT10919 Positive_regulation of ITGB2 25 0.67 13.75 5.45 5.00
81 INT77281 Negative_regulation of HIVEP1 132 0.49 102.78 5.36 5.00
82 INT171562 Regulation of IL4 19 0.36 12.12 5.33 5.00
83 INT60252 Binding of HIVEP1 59 0.32 65.12 5.06 5.00
84 INT194380 Negative_regulation of Gene_expression of IL5 22 0.42 15.78 4.1 5.00
85 INT204529 Positive_regulation of TLR9 18 0.62 15.62 3.99 5.00
86 INT85130 Regulation of IL5 14 0.27 8.37 3.55 5.00
87 INT9999 Regulation of Gene_expression of IGHE 32 0.60 15.75 3.53 5.00
88 INT73500 Regulation of IL13 12 0.36 10.37 3.53 5.00
89 INT118615 Negative_regulation of IL4 20 0.41 13.79 3.49 5.00
90 INT200443 Positive_regulation of AES 27 0.60 22.46 3.22 5.00
91 INT24873 Binding of KLF1 12 0.07 6.73 3.1 5.00
92 INT177586 Positive_regulation of Gene_expression of MRI1 9 0.33 4.97 2.91 5.00
93 INT7142 Positive_regulation of DLD 22 0.60 7.69 2.76 5.00
94 INT11686 Regulation of IL3 15 0.45 8.69 2.54 5.00
95 INT32421 Gene_expression of FCER2 19 0.73 17.23 2.53 5.00
96 INT226492 Negative_regulation of IL13 11 0.28 7.17 2.04 5.00
97 INT43900 Gene_expression of RASA1 13 0.58 12 2.03 5.00
98 INT9427 Binding of TBXA2R 8 0.31 2.71 1.91 5.00
99 INT94084 Regulation of Gene_expression of IL13 6 0.22 3.55 1.9 5.00
100 INT65611 Regulation of OR3A1 3 0.03 0.74 1.77 5.00
101 INT217070 Gene_expression of Acsm3 8 0.25 6.27 1.75 5.00
102 INT20992 Regulation of ITGB2 11 0.37 9.04 1.73 5.00
103 INT25163 Positive_regulation of Gene_expression of IL2RA 8 0.45 5.37 1.71 5.00
104 INT85411 Regulation of IL9 4 0.10 0.85 1.65 5.00
105 INT234761 Binding of IL13 6 0.35 4.18 1.55 5.00
106 INT14916 Binding of RASA1 15 0.37 13.64 1.44 5.00
107 INT56365 Regulation of Gene_expression of ITGB2 5 0.60 3.87 1.36 5.00
108 INT136574 Regulation of TNFAIP3 2 0.11 1.33 1.3 5.00
109 INT120764 Negative_regulation of Binding of JUN 7 0.25 2.65 1.23 5.00
110 INT226434 Positive_regulation of CCR3 8 0.35 4.87 1.07 5.00
111 INT126572 Positive_regulation of SYK 3 0.67 2.98 0.83 5.00
112 INT269401 Regulation of Gene_expression of TMPO 8 0.18 2.89 0.78 5.00
113 INT82051 Negative_regulation of RNASE3 8 0.32 6.81 0.53 5.00
114 INT171745 Transcription of CCR3 2 0.37 2.32 0.44 5.00
115 INT353079 Regulation of Regulation of OR3A1 1 0.00 0.15 0.4 5.00
116 INT189591 Regulation of SPARCL1 3 0.25 2.99 0.4 5.00
117 INT154175 Regulation of SYK 2 0.62 1.48 0.34 5.00
118 INT334503 Regulation of Gene_expression of FCER2 1 0.02 0.69 0.29 5.00
119 INT308528 Regulation of CCR3 2 0.31 2.23 0.2 5.00
120 INT334510 Negative_regulation of CCR3 1 0.30 1.4 0.1 5.00
121 INT334511 Positive_regulation of Transcription of ITGB2 1 0.02 1.48 0.08 5.00
122 INT334515 Transcription of ITGB2 1 0.02 1.47 0.08 5.00
123 INT334512 Gene_expression of IGKV6D-41 1 0.65 0.49 0.06 5.00
124 INT190903 Regulation of Negative_regulation of HIVEP1 2 0.03 2.05 0.06 5.00
125 INT334509 Negative_regulation of Negative_regulation of CCR3 1 0.30 0.7 0.05 5.00
126 INT300275 Positive_regulation of CPSF4 1 0.07 1.02 0.03 5.00
127 INT300274 Positive_regulation of PSMB4 1 0.01 1.08 0 5.00
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