D:Lead Poisoning

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms LEAD POISONINGS, Poisoning Lead, Poisonings Lead
Documents 161
Hot Single Events 12
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Lead Poisoning. They are ordered first by their relevance to Lead Poisoning and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT296372 Binding of IDUA and ACD 1 0.03 2.72 0.23 5.00
2 INT188985 Binding of MKLN1 and CHPT1 1 0.06 0 0.19 5.00
3 INT282684 FECH Positive_regulation of Negative_regulation of Ssbp3 1 0.00 1.54 0.08 5.00
4 INT175832 Binding of GML and SLC25A11 1 0.10 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Lead Poisoning. They are ordered first by their pain relevance and then by number of times they were reported in Lead Poisoning. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT20936 Binding of MGP 13 0.40 3.55 3.59 99.76
2 INT39677 Negative_regulation of Atrn 6 0.17 2.17 1.79 97.24
3 INT120652 Positive_regulation of Alad 2 0.42 1.2 0.12 92.80
4 INT157932 Positive_regulation of ADHD1 46 0.48 52.18 6.13 90.96
5 INT58409 Negative_regulation of Alad 5 0.43 1.15 0.32 88.80
6 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 87.60
7 INT242866 Regulation of HFE 2 0.39 1.84 0 85.84
8 INT7581 Binding of ADHD1 132 0.46 135.1 19.73 84.64
9 INT199809 Negative_regulation of hb 20 0.36 13.26 1.86 83.44
10 INT48513 Positive_regulation of MMEL1 2 0.38 0.6 0.15 81.20
11 INT37866 Negative_regulation of Alad 4 0.35 3.17 1.41 80.72
12 INT40215 Negative_regulation of Fech 9 0.57 8.39 1.85 80.72
13 INT171428 Gene_expression of AKAP13 2 0.02 0.86 0 79.24
14 INT84250 Positive_regulation of IDUA 8 0.56 15.89 0.62 79.12
15 INT296382 Positive_regulation of SLC11A2 3 0.31 1.49 0.08 79.12
16 INT12915 Gene_expression of MGP 18 0.75 7.53 4.15 78.80
17 INT327509 Binding of Alad 1 0.20 0.54 0.03 78.40
18 INT327512 Positive_regulation of Binding of Alad 1 0.27 0.54 0.03 78.40
19 INT50291 Positive_regulation of HMBS 10 0.67 8.89 0.73 75.68
20 INT120657 Positive_regulation of Localization of HMBS 1 0.00 0.83 0.09 75.68
21 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 75.00
22 INT2241 Negative_regulation of CEL 56 0.58 29.32 8.83 75.00
23 INT44920 Negative_regulation of IK 18 0.41 9.9 7.16 75.00
24 INT44919 Negative_regulation of ALAD 5 0.43 3.11 0.8 75.00
25 INT8773 Gene_expression of HBG1 58 0.76 37.6 4.59 75.00
26 INT178221 Negative_regulation of Gene_expression of HBG1 3 0.33 2.43 0.13 75.00
27 INT120656 Localization of HMBS 3 0.16 2.6 0.23 71.60
28 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45 69.28
29 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 67.76
30 INT1166 Negative_regulation of Dbh 56 0.59 12.54 28.26 64.64
31 INT1792 Positive_regulation of CGA 123 0.70 64.73 20.79 63.84
32 INT41892 Gene_expression of HBM 48 0.64 28.32 5.64 62.36
33 INT171426 Positive_regulation of DNLZ 3 0.09 1.31 0.03 61.56
34 INT171425 Negative_regulation of EIF2AK1 2 0.01 0.54 0 59.44
35 INT60585 Regulation of TP53 59 0.59 54.55 5.21 58.08
36 INT171419 Negative_regulation of Alas1 1 0.01 0.4 0 56.56
37 INT174590 Regulation of GLG1 5 0.27 5.54 0.72 56.44
38 INT64888 Negative_regulation of HBM 52 0.16 34.33 5.45 54.80
39 INT293892 Regulation of Sgpp1 1 0.01 0.15 0 54.48
40 INT60474 Negative_regulation of Gene_expression of Hdlcl1 1 0.05 0.66 0.08 52.72
41 INT24643 Gene_expression of Hdlcl1 30 0.73 26.83 1.9 50.72
42 INT19488 Localization of ABAT 56 0.69 21.51 50.56 50.00
43 INT64225 Positive_regulation of Localization of ABAT 15 0.60 4.46 11.28 50.00
44 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 39.80
45 INT111223 Positive_regulation of HMOX1 47 0.70 39.14 10.92 37.28
46 INT4479 Negative_regulation of Positive_regulation of REN 17 0.56 6.1 3.27 32.80
47 INT38989 Gene_expression of IDUA 22 0.78 16.99 1.26 32.80
48 INT169435 Gene_expression of CHPT1 17 0.61 10.04 7.37 28.40
49 INT90909 Negative_regulation of Gene_expression of NOS1 44 0.55 23.83 12.47 24.88
50 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 23.84
51 INT186251 Negative_regulation of Gene_expression of B4GALNT1 5 0.07 1.84 1.07 16.96
52 INT79062 Gene_expression of B4GALNT1 42 0.14 18.89 6.98 16.56
53 INT171421 Regulation of Positive_regulation of TP53 1 0.48 0.45 0.05 8.76
54 INT95397 Gene_expression of Pgrmc1 6 0.35 2.98 1.81 8.08
55 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 7.16
56 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 5.00
57 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
58 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
59 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19 5.00
60 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
61 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 5.00
62 INT7340 Regulation of Grin1 87 0.62 30.37 57.93 5.00
63 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
64 INT60710 Gene_expression of Col7a1 217 0.78 113.2 35.2 5.00
65 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 5.00
66 INT605 Regulation of Acot1 61 0.62 10.7 26.34 5.00
67 INT170444 Binding of Gopc 172 0.39 45.05 20.71 5.00
68 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 5.00
69 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 5.00
70 INT18773 Localization of ALB 117 0.80 69.18 13.8 5.00
71 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 5.00
72 INT8548 Gene_expression of HP 86 0.77 47.62 11.94 5.00
73 INT184853 Gene_expression of ADHD1 87 0.65 89.2 11.8 5.00
74 INT13240 Gene_expression of TF 94 0.76 57.81 10.99 5.00
75 INT94784 Binding of ROS1 113 0.40 71.57 10.26 5.00
76 INT3287 Gene_expression of Gpt 50 0.75 23.69 8.57 5.00
77 INT113987 Localization of IK 29 0.23 16.73 8.25 5.00
78 INT93607 Binding of CHPT1 8 0.32 5.93 7.58 5.00
79 INT24800 Negative_regulation of AMPD1 44 0.59 21.19 6.76 5.00
80 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 5.00
81 INT2039 Regulation of CYP2B6 30 0.60 7.75 6.43 5.00
82 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 5.00
83 INT81049 Positive_regulation of CASP1 44 0.67 19.97 5.69 5.00
84 INT95048 Negative_regulation of ADHD1 61 0.51 56.01 5.62 5.00
85 INT5490 Binding of CA2 52 0.36 9.73 5.53 5.00
86 INT71418 Binding of CES1 42 0.40 29.78 5.01 5.00
87 INT57368 Regulation of ADHD1 39 0.50 42.23 5.01 5.00
88 INT3163 Gene_expression of NAGLU 28 0.75 15.23 4.98 5.00
89 INT80486 Gene_expression of FECH 13 0.54 10.42 4.8 5.00
90 INT18011 Positive_regulation of HP 60 0.50 31.88 4.75 5.00
91 INT88414 Negative_regulation of CDK2 30 0.57 18.4 3.96 5.00
92 INT12189 Localization of Gpt 8 0.73 3.63 3.92 5.00
93 INT120062 Binding of AIP 4 0.42 28.86 3.91 5.00
94 INT181922 Binding of RENBP 16 0.36 13.92 3.71 5.00
95 INT51841 Positive_regulation of CHPT1 13 0.43 6.82 3.62 5.00
96 INT117754 Gene_expression of NHS 34 0.57 9.27 3.28 5.00
97 INT20006 Gene_expression of MT1F 27 0.68 19.55 3.18 5.00
98 INT32852 Negative_regulation of FECH 18 0.57 10.59 3.08 5.00
99 INT38362 Positive_regulation of Wbc1 19 0.06 13.24 2.95 5.00
100 INT46650 Localization of Trf 13 0.61 4.4 2.91 5.00
101 INT45503 Binding of EPO 42 0.48 24.85 2.88 5.00
102 INT15509 Negative_regulation of HMBS 14 0.58 13.13 2.78 5.00
103 INT145279 Regulation of hb 19 0.34 16.58 2.41 5.00
104 INT243496 Positive_regulation of Gene_expression of FECH 4 0.40 4.02 2.34 5.00
105 INT9188 Localization of HBG1 12 0.75 8.14 2.24 5.00
106 INT111461 Positive_regulation of hb 30 0.38 21.08 2.1 5.00
107 INT38008 Positive_regulation of Gene_expression of NAGLU 6 0.44 6.64 2 5.00
108 INT53567 Positive_regulation of FECH 14 0.45 11.03 1.82 5.00
109 INT189003 Localization of CHPT1 8 0.64 4.75 1.82 5.00
110 INT84820 Negative_regulation of Negative_regulation of Ngf 5 0.59 2.5 1.79 5.00
111 INT157720 Localization of ADHD1 15 0.64 15.84 1.69 5.00
112 INT58931 Binding of NAGLU 11 0.34 4.47 1.63 5.00
113 INT71515 Negative_regulation of CHPT1 6 0.38 2.28 1.51 5.00
114 INT127038 Gene_expression of Alas1 6 0.72 3.94 1.48 5.00
115 INT27762 Positive_regulation of Gene_expression of EPO 18 0.70 17.67 1.45 5.00
116 INT188993 Gene_expression of MKLN1 2 0.38 9.71 1.43 5.00
117 INT161276 Regulation of NHS 7 0.38 1.43 1.4 5.00
118 INT215946 Localization of Phc1 33 0.10 8.41 1.39 5.00
119 INT179644 Gene_expression of RENBP 26 0.35 13.74 1.38 5.00
120 INT20937 Regulation of MGP 4 0.43 0.62 1.37 5.00
121 INT38990 Negative_regulation of IDUA 12 0.59 5.04 1.33 5.00
122 INT49978 Localization of Hbb 4 0.39 1.11 1.29 5.00
123 INT132453 Binding of TF 31 0.36 12.98 1.22 5.00
124 INT162831 Regulation of ARSD 13 0.35 6.17 1.19 5.00
125 INT188992 Positive_regulation of Localization of CHPT1 2 0.43 0.36 1.17 5.00
126 INT11063 Negative_regulation of CES1 16 0.53 6.92 1.11 5.00
127 INT115264 Binding of FECH 9 0.41 7.93 1.1 5.00
128 INT3288 Positive_regulation of Gene_expression of Gpt 9 0.49 5.55 1.1 5.00
129 INT147602 Negative_regulation of CDK4 8 0.35 4.6 1.04 5.00
130 INT296385 Binding of IDUA 12 0.39 20.73 0.93 5.00
131 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75 5.00
132 INT242371 Regulation of Gene_expression of ADHD1 3 0.37 5.2 0.65 5.00
133 INT17493 Binding of Ar 14 0.48 3.62 0.6 5.00
134 INT127291 Transcription of ALB 7 0.67 4.26 0.55 5.00
135 INT84826 Negative_regulation of ACD 6 0.50 4.02 0.55 5.00
136 INT28097 Negative_regulation of Wbc1 8 0.11 4.07 0.53 5.00
137 INT56268 Negative_regulation of Gene_expression of F8a1 2 0.02 1.29 0.52 5.00
138 INT112215 Binding of Vdr 4 0.31 2.43 0.44 5.00
139 INT20007 Regulation of Gene_expression of MT1F 4 0.07 2.35 0.43 5.00
140 INT189002 Binding of MKLN1 2 0.24 0.97 0.38 5.00
141 INT5223 Negative_regulation of PDP1 8 0.41 1.74 0.37 5.00
142 INT281012 Negative_regulation of NPCDR1 1 0.43 1.26 0.36 5.00
143 INT160801 Gene_expression of OTC 6 0.59 0.99 0.36 5.00
144 INT56266 Gene_expression of F8a1 2 0.03 0.69 0.35 5.00
145 INT222311 Gene_expression of IGKV1-16 4 0.15 4.64 0.3 5.00
146 INT128916 Regulation of CES1 5 0.40 2.95 0.29 5.00
147 INT282679 Localization of FECH 1 0.12 9.57 0.23 5.00
148 INT159113 Binding of MT1F 5 0.42 1.85 0.23 5.00
149 INT172109 Gene_expression of SLC26A3 4 0.53 2.28 0.23 5.00
150 INT174581 Negative_regulation of Gene_expression of NHS 3 0.32 1.16 0.2 5.00
151 INT84244 Positive_regulation of Gene_expression of IDUA 5 0.70 3.75 0.19 5.00
152 INT171423 Regulation of DNLZ 2 0.10 1.8 0.19 5.00
153 INT187051 Positive_regulation of Gene_expression of RENBP 3 0.09 2.04 0.18 5.00
154 INT175834 Localization of SARS 6 0.39 6.23 0.17 5.00
155 INT189390 Positive_regulation of MT1F 5 0.08 0.85 0.14 5.00
156 INT307240 Localization of CYLD 3 0.72 3.09 0.1 5.00
157 INT281427 Positive_regulation of MGP 5 0.67 1.35 0.09 5.00
158 INT189001 Phosphorylation of CHPT1 1 0.58 0 0.09 5.00
159 INT188999 Positive_regulation of Phosphorylation of CHPT1 1 0.36 0 0.09 5.00
160 INT282678 Negative_regulation of Ssbp3 1 0.02 1.53 0.08 5.00
161 INT291143 Binding of PDP1 3 0.34 0.5 0.08 5.00
162 INT188990 Regulation of Gene_expression of CHPT1 2 0.32 0 0.08 5.00
163 INT279349 Localization of IDUA 7 0.76 4.97 0.07 5.00
164 INT171422 Regulation of EPHB6 1 0.44 0.53 0.07 5.00
165 INT188996 Regulation of Localization of CHPT1 1 0.32 0.25 0.05 5.00
166 INT162956 Binding of ACD 3 0.32 3.04 0.05 5.00
167 INT259952 Negative_regulation of Negative_regulation of ALB 1 0.42 1.24 0.04 5.00
168 INT188994 Positive_regulation of Gene_expression of MKLN1 1 0.10 0.51 0.03 5.00
169 INT296384 Regulation of SLC40A1 2 0.01 0.83 0.03 5.00
170 INT296386 Localization of DEFA6 3 0.05 0.88 0 5.00
171 INT281426 Protein_catabolism of MGP 1 0.85 0.1 0 5.00
172 INT186639 Gene_expression of SLC11A2 4 0.65 1.91 0 5.00
173 INT188995 Transcription of MKLN1 1 0.14 0.3 0 5.00
174 INT175837 Negative_regulation of USH2A 1 0.01 0 0 5.00
175 INT327486 Binding of Dpa 1 0.02 1.74 0 5.00
176 INT175836 Gene_expression of GML 1 0.38 0 0 5.00
177 INT282677 Gene_expression of Ssbp3 1 0.03 0.89 0 5.00
178 INT200395 Gene_expression of DUOXA1 2 0.11 0.59 0 5.00
179 INT200390 Localization of DUOXA1 2 0.13 0 0 5.00
180 INT327511 Negative_regulation of Negative_regulation of Alad 1 0.23 0.29 0 5.00
181 INT275258 Binding of DUOXA1 1 0.06 0 0 5.00
182 INT296383 Regulation of SLC11A2 1 0.07 0.33 0 5.00
183 INT327510 Negative_regulation of Sqstm1 1 0.01 0.41 0 5.00
184 INT171427 Gene_expression of TGDS 1 0.04 0.14 0 5.00
185 INT175835 Protein_catabolism of GML 1 0.50 0 0 5.00
186 INT327507 Negative_regulation of Localization of CYLD 1 0.05 0.58 0 5.00
187 INT344729 Positive_regulation of Gene_expression of SLC26A3 1 0.39 0.08 0 5.00
188 INT296387 Localization of SLC40A1 2 0.44 0.94 0 5.00
189 INT281425 Localization of MGP 1 0.63 0.1 0 5.00
190 INT327508 Localization of CYBRD1 1 0.01 0.24 0 5.00
191 INT210076 Localization of HBB 1 0.15 0 0 5.00
192 INT327506 Localization of IGKV1-16 1 0.05 0.52 0 5.00
193 INT171424 Gene_expression of EIF2AK1 1 0.01 0.14 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox