D:Leiomyomatosis

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms LEIOMYOMATOSES
Documents 57
Hot Single Events 17
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Leiomyomatosis. They are ordered first by their relevance to Leiomyomatosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT139538 Binding of CD34 and KIT 2 0.39 2.73 0.14 89.84
2 INT278068 Binding of XRCC1 and Vhl 1 0.02 2.3 0 83.84
3 INT193193 Binding of CRS and RAPH1 1 0.12 1.47 0 69.92
4 INT74015 Binding of VHL and XRCC1 1 0.07 3.51 0.09 5.00
5 INT278059 XRCC1 Positive_regulation of Gene_expression of IL2 1 0.01 1.06 0.07 5.00
6 INT241120 Binding of Sdhc and Sdhd 1 0.00 1.28 0 5.00
7 INT241119 Binding of Sdhc and Sdhb 1 0.00 1.29 0 5.00
8 INT251983 XRCC1 Regulation of Binding of MET 1 0.05 0.4 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Leiomyomatosis. They are ordered first by their pain relevance and then by number of times they were reported in Leiomyomatosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT100375 Gene_expression of Vhl 14 0.15 22.3 1.69 100.00
2 INT68665 Binding of Vhl 9 0.48 10.3 0.82 99.12
3 INT241113 Negative_regulation of Binding of Vhl 1 0.07 3.31 0.03 99.12
4 INT152215 Binding of FH 10 0.41 14.13 0.19 95.96
5 INT9397 Regulation of MET 17 0.60 8.36 7.04 94.24
6 INT241115 Regulation of Vhl 5 0.15 8.36 0.11 94.24
7 INT73731 Binding of RAPH1 9 0.33 14.58 0.5 94.16
8 INT152214 Gene_expression of Fh 1 0.04 0.83 0 92.88
9 INT241104 Gene_expression of FH 7 0.66 20.35 0.31 92.16
10 INT85085 Positive_regulation of KIT 36 0.53 30.08 2.17 89.84
11 INT18995 Binding of CEL 23 0.47 14.46 4.5 89.36
12 INT21681 Positive_regulation of CD34 54 0.66 33.95 4.14 89.04
13 INT241100 Negative_regulation of Binding of FH 1 0.11 2.76 0.05 87.60
14 INT97973 Positive_regulation of XRCC1 24 0.40 30.95 2.26 86.72
15 INT51607 Positive_regulation of DES 33 0.67 32.24 3.29 86.24
16 INT85280 Positive_regulation of FH 2 0.45 3.53 0.09 83.20
17 INT74016 Binding of VHL 20 0.48 15.49 0.54 80.04
18 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 78.32
19 INT74021 Regulation of XRCC1 15 0.44 16.91 0.88 78.16
20 INT152213 Negative_regulation of Fh 1 0.03 0.94 0.09 75.00
21 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 75.00
22 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19 75.00
23 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 75.00
24 INT241099 Positive_regulation of Gene_expression of FH 3 0.43 5.17 0.11 73.84
25 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 73.24
26 INT121493 Gene_expression of XRCC1 55 0.65 73.43 2.76 71.24
27 INT241114 Transcription of Vhl 1 0.11 2.3 0.05 69.28
28 INT241102 Transcription of FH 2 0.59 2 0.14 67.00
29 INT60279 Gene_expression of VHL 70 0.78 75.21 2.21 66.68
30 INT200219 Positive_regulation of VHL 18 0.50 15.38 0.67 66.68
31 INT187656 Positive_regulation of RAPH1 1 0.31 1.73 0.14 66.32
32 INT241101 Negative_regulation of Gene_expression of FH 2 0.42 3.16 0 59.52
33 INT278061 Negative_regulation of Binding of Vhl 1 0.26 1.7 0 55.80
34 INT199571 Binding of Vhl 3 0.23 3.4 0.07 55.28
35 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 50.00
36 INT3933 Positive_regulation of PLOD1 128 0.70 30.76 42.03 50.00
37 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 50.00
38 INT49805 Positive_regulation of MUC1 56 0.70 44.5 4.56 50.00
39 INT10353 Positive_regulation of PGR 34 0.70 21.84 3.28 50.00
40 INT59784 Binding of DES 22 0.47 19.48 2.27 50.00
41 INT55284 Regulation of CTPP 3 0.60 1.07 1.31 50.00
42 INT90670 Positive_regulation of KRT1 10 0.44 6.25 1.16 50.00
43 INT183037 Gene_expression of MNX1 12 0.53 4.27 0.69 50.00
44 INT39865 Regulation of Positive_regulation of PLOD1 2 0.27 0.71 0.66 50.00
45 INT193196 Regulation of MNX1 2 0.19 2.53 0.64 50.00
46 INT193199 Gene_expression of RAPH1 6 0.60 4.55 0.36 50.00
47 INT193195 Localization of MNX1 1 0.59 1.01 0.03 50.00
48 INT193197 Localization of RAPH1 1 0.51 1.2 0 50.00
49 INT193198 Positive_regulation of Binding of DES 1 0.18 0.49 0 50.00
50 INT100376 Positive_regulation of Gene_expression of Vhl 4 0.10 6.47 1.47 48.88
51 INT278062 Negative_regulation of Vhl 2 0.33 2.72 0.04 48.32
52 INT241117 Regulation of Gene_expression of Vhl 1 0.06 2.5 0.07 35.96
53 INT121495 Transcription of XRCC1 7 0.49 6.11 0.09 31.04
54 INT241106 Localization of FH 1 0.20 2.1 0 28.20
55 INT241118 Negative_regulation of Vhl 3 0.11 4.01 0.08 14.20
56 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58 13.84
57 INT75694 Regulation of Gene_expression of CEL 9 0.60 6.08 1.53 13.84
58 INT165 Regulation of HRH1 12 0.45 1.76 7.57 13.60
59 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03 10.84
60 INT106020 Transcription of EPO 8 0.71 9.34 0.6 10.84
61 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
62 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
63 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
64 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 5.00
65 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 5.00
66 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87 5.00
67 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
68 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 5.00
69 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 5.00
70 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
71 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 5.00
72 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
73 INT14701 Negative_regulation of IFNA1 118 0.54 84.19 20.08 5.00
74 INT106097 Localization of pr 20 0.62 12.01 19.46 5.00
75 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99 5.00
76 INT34904 Negative_regulation of Gtf3a 48 0.15 38.88 13.73 5.00
77 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 5.00
78 INT12464 Binding of MET 38 0.47 10.3 13.15 5.00
79 INT12156 Positive_regulation of MET 43 0.67 17.75 12.64 5.00
80 INT73223 Gene_expression of UPF1 78 0.41 31.44 9.94 5.00
81 INT139329 Phosphorylation of IFNA1 24 0.79 16.19 5.95 5.00
82 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79 5.00
83 INT4922 Negative_regulation of MET 19 0.57 13.97 3.7 5.00
84 INT57272 Negative_regulation of Gene_expression of FN1 16 0.43 11.42 1.93 5.00
85 INT148702 Positive_regulation of UPF1 29 0.31 12.9 1.91 5.00
86 INT120519 Localization of XRCC1 15 0.78 17.03 1.51 5.00
87 INT74018 Binding of XRCC1 19 0.31 24.78 1.24 5.00
88 INT24297 Regulation of CYP21A2 3 0.05 1.29 1.09 5.00
89 INT74020 Negative_regulation of XRCC1 16 0.35 17.18 1.06 5.00
90 INT178209 Negative_regulation of Binding of IFNA1 7 0.39 4.8 0.89 5.00
91 INT173082 Positive_regulation of Binding of VEGFA 20 0.48 11.16 0.79 5.00
92 INT239496 Gene_expression of Aes 4 0.52 1.45 0.76 5.00
93 INT206929 Negative_regulation of Gene_expression of XRCC1 4 0.25 6.14 0.74 5.00
94 INT183672 Gene_expression of EPAS1 37 0.35 28.68 0.72 5.00
95 INT11551 Localization of VHL 12 0.65 22.76 0.68 5.00
96 INT23650 Positive_regulation of Sdhb 2 0.17 1.34 0.43 5.00
97 INT130999 Localization of PRKAB1 5 0.57 4.1 0.35 5.00
98 INT278065 Negative_regulation of Phosphorylation of IFNA1 2 0.39 0.68 0.31 5.00
99 INT173086 Negative_regulation of VHL 14 0.59 12.54 0.29 5.00
100 INT127654 Positive_regulation of Gene_expression of XRCC1 11 0.38 13.7 0.26 5.00
101 INT193015 Positive_regulation of Gene_expression of EPAS1 6 0.32 8.77 0.21 5.00
102 INT74017 Regulation of VHL 4 0.43 7.59 0.16 5.00
103 INT139331 Localization of Vhl 2 0.65 2.34 0.15 5.00
104 INT11552 Positive_regulation of Localization of VHL 2 0.44 2.12 0.13 5.00
105 INT173080 Positive_regulation of Gene_expression of VHL 3 0.50 9.58 0.1 5.00
106 INT224327 Negative_regulation of EPAS1 5 0.09 4.29 0.08 5.00
107 INT193016 Regulation of EPAS1 9 0.15 7.38 0.06 5.00
108 INT278064 Positive_regulation of Localization of XRCC1 1 0.05 1.17 0.05 5.00
109 INT278063 Regulation of Positive_regulation of XRCC1 1 0.03 1.2 0.05 5.00
110 INT251953 Positive_regulation of Transcription of XRCC1 1 0.29 1.07 0.04 5.00
111 INT241289 Regulation of AMACR 3 0.06 0.8 0.04 5.00
112 INT252002 Positive_regulation of Regulation of VHL 1 0.44 0.66 0 5.00
113 INT251999 Negative_regulation of Gene_expression of FLCN 1 0.35 1.03 0 5.00
114 INT252006 Negative_regulation of Binding of VHL 1 0.59 0.58 0 5.00
115 INT251996 Regulation of Gene_expression of FH 1 0.39 0.77 0 5.00
116 INT252005 Phosphorylation of VHL 1 0.81 0.48 0 5.00
117 INT252003 Regulation of Phosphorylation of VHL 1 0.45 0.48 0 5.00
118 INT185287 Transcription of VHL 2 0.60 3.77 0 5.00
119 INT252004 Negative_regulation of Regulation of EPAS1 1 0.02 1.17 0 5.00
120 INT251997 Negative_regulation of Transcription of VHL 1 0.37 1.32 0 5.00
121 INT210708 Regulation of Gene_expression of XRCC1 3 0.34 3.11 0 5.00
122 INT241107 Negative_regulation of Transcription of FLCN 1 0.02 2.38 0 5.00
123 INT235467 Negative_regulation of Gene_expression of VHL 9 0.43 8.67 0 5.00
124 INT252000 Negative_regulation of FH 4 0.37 1.44 0 5.00
125 INT252007 Regulation of Binding of FH 1 0.39 0.74 0 5.00
126 INT241116 Negative_regulation of Localization of Vhl 1 0.06 2.23 0 5.00
127 INT241103 Transcription of FLCN 1 0.04 2.36 0 5.00
128 INT241108 Binding of FLCN 2 0.31 7.33 0 5.00
129 INT241105 Gene_expression of FLCN 3 0.65 15.31 0 5.00
130 INT251995 Positive_regulation of Gene_expression of FLCN 1 0.42 1.08 0 5.00
131 INT251998 Protein_catabolism of EPAS1 2 0.03 2.68 0 5.00
132 INT252001 Negative_regulation of Negative_regulation of FH 1 0.37 0.43 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox