D:Leukemic Infiltration

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Infiltration Leukemic, Infiltrations Leukemic, Leukemic Infiltrations
Documents 29
Hot Single Events 0
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Leukemic Infiltration. They are ordered first by their relevance to Leukemic Infiltration and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56 5.00
2 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21 5.00
3 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 5.00
4 INT298641 PPARA Regulation of STAT3 1 0.23 0.98 0.16 5.00
5 INT298639 GDE1 Negative_regulation of AKT1 1 0.00 1.14 0.14 5.00
6 INT298634 Binding of IL6 and STAT3 1 0.04 1.41 0.08 5.00
7 INT298638 IL6 Positive_regulation of IL6R 1 0.00 0.9 0.05 5.00
8 INT298635 PPARA Negative_regulation of Localization of ZDHHC2 1 0.01 0.21 0.05 5.00
9 INT241536 Binding of Abcb1b and Abcg2 1 0.10 0.17 0.04 5.00
10 INT298683 ecs Positive_regulation of Gene_expression of VEGFA 1 0.02 1.41 0.04 5.00
11 INT298637 ZDHHC2 Negative_regulation of Gene_expression of VEGFA 1 0.01 0.27 0.04 5.00
12 INT298633 STAT3 Regulation of MCL1 1 0.04 0.85 0.03 5.00
13 INT298640 IL6R Positive_regulation of STAT3 1 0.01 0.73 0.03 5.00
14 INT298684 ecs Positive_regulation of Gene_expression of KDR 1 0.01 1.2 0 5.00
15 INT144032 STAT3 Regulation of BCL2 2 0.07 0.86 0 5.00
16 INT298632 STAT3 Positive_regulation of MIR21 1 0.03 0.84 0 5.00
17 INT241535 Abl1 Regulation of Positive_regulation of Jak2 1 0.10 0.53 0 5.00
18 INT241537 Negative_regulation of Binding of Abl1 and Src 1 0.04 0.14 0 5.00
19 INT241539 Binding of Abl1 and Lyn 1 0.09 0.14 0 5.00
20 INT241534 Binding of Abl1 and Src 1 0.04 0.14 0 5.00
21 INT241538 Negative_regulation of Binding of Abl1 and Lyn 1 0.11 0.14 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Leukemic Infiltration. They are ordered first by their pain relevance and then by number of times they were reported in Leukemic Infiltration. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 79.04
2 INT57336 Gene_expression of Cd19 5 0.46 4.8 1.6 79.04
3 INT6512 Gene_expression of PTH 103 0.77 76.29 6.33 54.32
4 INT46326 Gene_expression of Iresp1 2 0.01 1.32 0.45 26.56
5 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
6 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
7 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
8 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
9 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
10 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 5.00
11 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
12 INT15913 Negative_regulation of CYP2D6 174 0.59 22.45 70.91 5.00
13 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
14 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 5.00
15 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 5.00
16 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
17 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 5.00
18 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 5.00
19 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 5.00
20 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 5.00
21 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 5.00
22 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
23 INT114751 Gene_expression of Mapk1 137 0.76 60.14 39.98 5.00
24 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
25 INT103094 Binding of PPARA 308 0.47 177.26 34.75 5.00
26 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 5.00
27 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 5.00
28 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52 5.00
29 INT86437 Binding of IL6 154 0.48 121.22 29.3 5.00
30 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 5.00
31 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97 5.00
32 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 5.00
33 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 5.00
34 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41 5.00
35 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
36 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95 5.00
37 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61 5.00
38 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97 5.00
39 INT61626 Transcription of IL6 73 0.72 42.04 17.86 5.00
40 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95 5.00
41 INT59929 Negative_regulation of CYP2C9 60 0.59 16.33 15.39 5.00
42 INT1888 Protein_catabolism of F13A1 97 0.99 63.48 14.82 5.00
43 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66 5.00
44 INT103096 Regulation of PPARA 113 0.60 62.47 14.57 5.00
45 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53 5.00
46 INT20420 Gene_expression of MYC 99 0.75 49.32 14.36 5.00
47 INT72127 Protein_catabolism of MMRN1 68 0.52 56 14.13 5.00
48 INT114420 Negative_regulation of Pik3r1 67 0.54 34.86 12.82 5.00
49 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4 5.00
50 INT173159 Localization of PPARA 96 0.74 64.55 10.26 5.00
51 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79 5.00
52 INT122584 Negative_regulation of Gene_expression of PPARA 56 0.58 37.61 9.76 5.00
53 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 5.00
54 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37 5.00
55 INT51530 Negative_regulation of Adk 11 0.56 3.83 9.07 5.00
56 INT25381 Localization of Csf2 62 0.76 47.48 9.03 5.00
57 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68 5.00
58 INT91370 Phosphorylation of STAT3 123 0.82 49.25 8.42 5.00
59 INT1150 Gene_expression of ecs 42 0.59 29.38 7.73 5.00
60 INT103154 Gene_expression of FLT1 138 0.76 58.5 7.41 5.00
61 INT181194 Regulation of Gene_expression of PPARA 31 0.44 21.27 5.96 5.00
62 INT64724 Positive_regulation of Transcription of IL6 26 0.69 13.63 5.96 5.00
63 INT93684 Gene_expression of STAT3 66 0.78 34.42 5.94 5.00
64 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78 5.00
65 INT86025 Positive_regulation of Positive_regulation of PPARA 34 0.52 22.89 5.74 5.00
66 INT11360 Localization of SERPINE1 41 0.80 33.98 5.61 5.00
67 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19 5.00
68 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9 5.00
69 INT103155 Gene_expression of KDR 78 0.66 50.53 4.38 5.00
70 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17 5.00
71 INT91371 Negative_regulation of STAT3 34 0.59 25 4.08 5.00
72 INT88545 Localization of MMRN1 21 0.78 16.67 4.01 5.00
73 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95 5.00
74 INT1149 Binding of ecs 19 0.37 13.67 3.9 5.00
75 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75 5.00
76 INT121818 Binding of STAT3 25 0.47 11.16 3.67 5.00
77 INT90406 Gene_expression of IL6R 27 0.38 15.74 3.64 5.00
78 INT124185 Negative_regulation of Kit 57 0.59 35.43 3.61 5.00
79 INT169495 Negative_regulation of Mirlet7a-1 10 0.58 4 3.53 5.00
80 INT10106 Positive_regulation of Msr1 16 0.50 5.86 3.52 5.00
81 INT130295 Gene_expression of Abcg2 21 0.75 9.75 3.42 5.00
82 INT91173 Gene_expression of Pdgfrb 33 0.65 32.55 3.09 5.00
83 INT105783 Protein_catabolism of IL6 7 0.48 4.72 2.95 5.00
84 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88 5.00
85 INT164582 Negative_regulation of MCL1 56 0.56 67.11 2.82 5.00
86 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57 5.00
87 INT122709 Localization of CYP3A4 16 0.75 5.41 2.38 5.00
88 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37 5.00
89 INT151449 Negative_regulation of Gene_expression of Kit 18 0.45 12.05 2.23 5.00
90 INT58469 Negative_regulation of Positive_regulation of IL6 16 0.42 8.1 2.14 5.00
91 INT112364 Negative_regulation of HIF1A 22 0.57 16.95 2.13 5.00
92 INT37394 Localization of ecs 9 0.34 6.41 2.11 5.00
93 INT171514 Binding of EP300 13 0.32 4.32 2.01 5.00
94 INT99572 Localization of Kit 13 0.75 5.23 1.95 5.00
95 INT199084 Gene_expression of Cd36 31 0.53 16.94 1.94 5.00
96 INT101243 Regulation of STAT3 12 0.62 9.98 1.92 5.00
97 INT173180 Positive_regulation of Binding of PPARA 14 0.49 3.66 1.88 5.00
98 INT146943 Gene_expression of Src 13 0.49 6.65 1.65 5.00
99 INT25384 Positive_regulation of Localization of Csf2 11 0.66 7.81 1.62 5.00
100 INT119048 Negative_regulation of Gene_expression of HIF1A 10 0.57 9.23 1.5 5.00
101 INT173198 Regulation of Binding of PPARA 17 0.43 9.58 1.47 5.00
102 INT166021 Positive_regulation of MCL1 36 0.67 62.97 1.44 5.00
103 INT112963 Regulation of Positive_regulation of PPARA 8 0.44 5.29 1.43 5.00
104 INT258548 Positive_regulation of Meta 10 0.67 5.05 1.42 5.00
105 INT140296 Negative_regulation of XIAP 9 0.45 13.61 1.37 5.00
106 INT143716 Phosphorylation of Chuk 16 0.41 5.25 1.35 5.00
107 INT215380 Positive_regulation of Gene_expression of Cd36 12 0.47 8.51 1.3 5.00
108 INT144019 Negative_regulation of Pdgfrb 21 0.58 14.93 1.26 5.00
109 INT164325 Negative_regulation of Abcg2 6 0.39 1.88 1.2 5.00
110 INT123877 Negative_regulation of ABL1 40 0.57 27.94 1.17 5.00
111 INT206136 Positive_regulation of Gene_expression of STAT3 14 0.46 4.3 1.1 5.00
112 INT51264 Positive_regulation of TXK 21 0.54 10.69 1.1 5.00
113 INT102249 Binding of HIF1A 39 0.36 30.47 1.04 5.00
114 INT164324 Negative_regulation of Gene_expression of Abcg2 4 0.45 1.03 0.99 5.00
115 INT73939 Negative_regulation of Cd36 7 0.57 6.3 0.95 5.00
116 INT167546 Positive_regulation of Gene_expression of ecs 6 0.07 5.78 0.92 5.00
117 INT64958 Negative_regulation of Transcription of IL6 6 0.50 3.58 0.92 5.00
118 INT199563 Negative_regulation of Abl1 38 0.46 21.5 0.87 5.00
119 INT48717 Positive_regulation of Localization of SERPINE1 6 0.66 2.64 0.83 5.00
120 INT100378 Protein_catabolism of HIF1A 7 0.96 5.05 0.8 5.00
121 INT178485 Binding of Cd36 11 0.22 6.65 0.8 5.00
122 INT173082 Positive_regulation of Binding of VEGFA 20 0.48 11.16 0.79 5.00
123 INT76751 Negative_regulation of Protein_catabolism of F13A1 7 0.13 5.16 0.79 5.00
124 INT241499 Binding of Abl1 23 0.47 8.86 0.75 5.00
125 INT199573 Gene_expression of Abl1 33 0.65 20.79 0.75 5.00
126 INT209935 Regulation of Regulation of PPARA 4 0.44 1.56 0.69 5.00
127 INT171364 Localization of Pdgfrb 6 0.37 4.98 0.68 5.00
128 INT100382 Positive_regulation of Protein_catabolism of HIF1A 2 0.45 1.75 0.64 5.00
129 INT142005 Gene_expression of COL18A1 6 0.75 4.53 0.62 5.00
130 INT217168 Gene_expression of MIR21 30 0.55 30.86 0.62 5.00
131 INT159864 Localization of CYP3A5 2 0.73 0.33 0.52 5.00
132 INT91372 Negative_regulation of Positive_regulation of STAT3 8 0.40 2 0.5 5.00
133 INT56094 Protein_catabolism of SERPINE1 2 0.61 1.66 0.47 5.00
134 INT213789 Phosphorylation of Kit 7 0.69 5.32 0.43 5.00
135 INT298656 Positive_regulation of Gene_expression of MIR221 2 0.21 12.91 0.42 5.00
136 INT70884 Localization of Pdgfb 8 0.35 6.22 0.42 5.00
137 INT217156 Positive_regulation of Gene_expression of MIR21 9 0.49 16.04 0.38 5.00
138 INT173097 Localization of KDR 20 0.73 12.73 0.31 5.00
139 INT144021 Binding of Pdgfrb 9 0.37 5.53 0.28 5.00
140 INT217182 Gene_expression of MIR221 4 0.58 9.33 0.27 5.00
141 INT298661 Gene_expression of GDE1 5 0.04 3.42 0.26 5.00
142 INT94144 Localization of ZDHHC2 2 0.13 0.59 0.26 5.00
143 INT298665 Positive_regulation of Protein_catabolism of IL6 1 0.09 2.03 0.25 5.00
144 INT298644 Positive_regulation of Positive_regulation of Meta 1 0.67 1.4 0.23 5.00
145 INT265327 Negative_regulation of Binding of ecs 3 0.13 2.59 0.23 5.00
146 INT241498 Regulation of Abl1 8 0.32 6.46 0.22 5.00
147 INT206166 Negative_regulation of Binding of STAT3 4 0.55 1.13 0.2 5.00
148 INT222836 Negative_regulation of Phosphorylation of Chuk 5 0.16 0.98 0.19 5.00
149 INT199561 Positive_regulation of Gene_expression of Abl1 8 0.36 4.77 0.16 5.00
150 INT200802 Regulation of Jak2 5 0.61 2.86 0.16 5.00
151 INT298653 Positive_regulation of Binding of EP300 1 0.11 0.8 0.15 5.00
152 INT158508 Negative_regulation of Gene_expression of STAT3 2 0.43 1.74 0.15 5.00
153 INT271573 Binding of SCPEP1 3 0.35 1.21 0.13 5.00
154 INT298669 Negative_regulation of Protein_catabolism of IL6 1 0.08 1.02 0.13 5.00
155 INT298642 Positive_regulation of Protein_catabolism of Mirlet7a-1 1 0.02 1.02 0.13 5.00
156 INT298643 Protein_catabolism of Mirlet7a-1 1 0.03 1 0.13 5.00
157 INT298664 Gene_expression of MIR382 1 0.08 1.17 0.12 5.00
158 INT217189 Gene_expression of MIR222 5 0.46 4.58 0.12 5.00
159 INT298666 Positive_regulation of Gene_expression of MIR382 1 0.06 1.17 0.12 5.00
160 INT268552 Positive_regulation of Gene_expression of MIR222 4 0.21 4.06 0.12 5.00
161 INT241504 Negative_regulation of Aurka 2 0.09 1.54 0.11 5.00
162 INT105392 Positive_regulation of Binding of HIF1A 5 0.45 3.83 0.1 5.00
163 INT298659 Gene_expression of MIR27A 2 0.65 1.19 0.09 5.00
164 INT241512 Phosphorylation of Abl1 4 0.59 2.68 0.09 5.00
165 INT241515 Negative_regulation of Phosphorylation of Abl1 3 0.30 1.36 0.09 5.00
166 INT175415 Negative_regulation of COX10 5 0.07 3.33 0.08 5.00
167 INT217173 Negative_regulation of MIR15B 6 0.42 4.37 0.08 5.00
168 INT298670 Regulation of Gene_expression of IL6R 1 0.01 0.43 0.07 5.00
169 INT298657 Negative_regulation of Gene_expression of COL18A1 1 0.41 1.34 0.07 5.00
170 INT144039 Negative_regulation of Negative_regulation of STAT3 2 0.55 0.85 0.07 5.00
171 INT241509 Negative_regulation of Gene_expression of Lyn 2 0.20 1.02 0.05 5.00
172 INT241507 Positive_regulation of Abl1 5 0.40 2.69 0.05 5.00
173 INT298660 Negative_regulation of Localization of ZDHHC2 1 0.02 0.22 0.04 5.00
174 INT241506 Localization of Abl1 2 0.54 2.37 0.04 5.00
175 INT196696 Negative_regulation of Cd36 5 0.18 5.5 0.04 5.00
176 INT206043 Transcription of Cd36 4 0.37 2.59 0.04 5.00
177 INT105389 Negative_regulation of Binding of HIF1A 4 0.42 3.2 0.03 5.00
178 INT241510 Negative_regulation of Phosphorylation of Kit 3 0.31 2.06 0.03 5.00
179 INT298658 Positive_regulation of SCPEP1 2 0.10 0.69 0.03 5.00
180 INT225256 Positive_regulation of Gene_expression of Src 3 0.20 0.75 0 5.00
181 INT298651 Negative_regulation of GDE1 1 0.03 0.87 0 5.00
182 INT298672 Negative_regulation of Gene_expression of MIR27A 1 0.42 1.2 0 5.00
183 INT298667 Negative_regulation of Gene_expression of GDE1 1 0.03 1.02 0 5.00
184 INT298673 Gene_expression of HOXA5 2 0.49 2.33 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox