D:Lichen Sclerosus Et Atrophicus

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Disease Term
Synonyms Lichen Sclerosus
Documents 62
Hot Single Events 16
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Lichen Sclerosus Et Atrophicus. They are ordered first by their relevance to Lichen Sclerosus Et Atrophicus and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT238005 Binding of Cxcr3 and Cxcl10 2 0.38 3.73 1.42 34.40
2 INT238009 Binding of Cxcr3 and Cxcl9 3 0.40 4.01 1.37 5.00
3 INT199593 Binding of TRPV1 and Myoz1 1 0.10 1.7 1.23 5.00
4 INT237999 Binding of Cxcr3 and Cxcl11 2 0.45 3.49 1.11 5.00
5 INT252602 Binding of Cxcl10 and Ppig 1 0.08 1.55 0.96 5.00
6 INT237083 Binding of Cxcl10 and Cxcl9 2 0.39 3.19 0.87 5.00
7 INT237084 Binding of Cxcl9 and Cxcl11 2 0.34 3.19 0.87 5.00
8 INT252603 Ppig Positive_regulation of Gene_expression of Cx3cl1 1 0.10 1.8 0.69 5.00
9 INT252605 Ppig Positive_regulation of Gene_expression of Cx3cr1 1 0.09 1.81 0.69 5.00
10 INT252601 Binding of Cxcl10 and Cxcl11 1 0.34 1.68 0.6 5.00
11 INT252599 Negative_regulation of Cxcl10 Negative_regulation of Gene_expression of Cxcr3 1 0.45 0.49 0.29 5.00
12 INT252604 Negative_regulation of Cxcl10 Negative_regulation of Gene_expression of Hand1 1 0.24 0.5 0.29 5.00
13 INT252606 IFNA1 Positive_regulation of Gene_expression of Cxcl10 1 0.02 0.56 0.18 5.00
14 INT252600 Ppig Regulation of Hand1 1 0.06 0.43 0.17 5.00
15 INT252598 Ppig Regulation of Gene_expression of Hand1 1 0.06 0.43 0.17 5.00
16 INT252020 Binding of HLA-A and ELOVL1 1 0.01 1.41 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Lichen Sclerosus Et Atrophicus. They are ordered first by their pain relevance and then by number of times they were reported in Lichen Sclerosus Et Atrophicus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT24889 Negative_regulation of CABIN1 36 0.48 16.76 4.73 99.84
2 INT231978 Binding of SERPINB3 9 0.36 8.33 0 98.68
3 INT99782 Negative_regulation of Cxcl10 21 0.55 18.4 6.5 95.84
4 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 95.16
5 INT146546 Gene_expression of MSI1 22 0.48 22.91 1.15 95.00
6 INT91703 Negative_regulation of Myoz1 78 0.58 53.78 13.5 92.16
7 INT239373 Positive_regulation of Positive_regulation of PTEN 3 0.25 4.98 0.12 91.80
8 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5 91.80
9 INT68285 Gene_expression of SERPINB3 24 0.75 25.4 0.45 91.76
10 INT68288 Positive_regulation of SERPINB3 14 0.51 16.87 0.41 90.76
11 INT350742 Positive_regulation of Positive_regulation of SERPINB3 1 0.04 2.54 0 90.76
12 INT68094 Negative_regulation of SERPINB3 12 0.43 10.55 1.49 89.16
13 INT104394 Positive_regulation of Gene_expression of Cxcl10 28 0.65 25.64 8.79 87.76
14 INT104392 Gene_expression of Cxcl10 113 0.75 106.86 34.12 87.32
15 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 80.40
16 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56 80.40
17 INT237054 Negative_regulation of Gene_expression of Cxcl10 11 0.56 10.26 3.4 73.28
18 INT174422 Binding of Cxcr3 24 0.47 26.09 8.34 67.36
19 INT164637 Binding of MIB1 3 0.32 4.29 0.11 59.88
20 INT78471 Regulation of Gene_expression of CDKN2A 13 0.45 12.52 3.28 58.76
21 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75 58.76
22 INT6852 Localization of TNF 883 0.81 705.95 270.84 58.40
23 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 57.96
24 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 50.00
25 INT67890 Positive_regulation of Gene_expression of SGCG 26 0.67 9.91 6.41 50.00
26 INT252582 Positive_regulation of Gene_expression of Ppig 3 0.12 2.62 1.13 47.56
27 INT65855 Localization of TP53 18 0.76 17.08 1.89 47.04
28 INT197627 Localization of RB1 3 0.69 4.16 0.13 46.72
29 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45 45.68
30 INT73266 Gene_expression of RB1 50 0.70 29.09 2.31 45.52
31 INT174197 Negative_regulation of Gene_expression of RB1 4 0.47 4.25 0 45.52
32 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 44.96
33 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51 44.88
34 INT127037 Gene_expression of Ppig 26 0.65 16.08 6.84 43.92
35 INT77076 Positive_regulation of Ppig 16 0.49 13.54 5.91 43.92
36 INT99787 Regulation of Cxcl10 9 0.43 6.37 3.02 42.36
37 INT172626 Localization of E2F1 3 0.78 1.97 0.4 39.40
38 INT184624 Localization of CDKN2A 8 0.74 7.87 0.25 39.40
39 INT350741 Binding of RNF123 1 0.01 1.15 0 35.48
40 INT170056 Binding of Cxcl10 11 0.45 12.72 5.32 34.40
41 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42 33.84
42 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38 33.48
43 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41 32.52
44 INT341719 Transcription of FAM49B 1 0.04 1.1 0 29.92
45 INT341718 Positive_regulation of Transcription of FAM49B 1 0.03 1.1 0 29.92
46 INT22815 Positive_regulation of RB1 20 0.49 14.58 1.26 29.80
47 INT129358 Gene_expression of ELOVL1 23 0.66 29.39 2.83 23.20
48 INT168410 Gene_expression of Cxcr3 81 0.75 84.03 37.01 22.32
49 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 16.60
50 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87 16.60
51 INT348463 Protein_catabolism of RB1 2 0.11 2.22 0 8.08
52 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 5.00
53 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
54 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 5.00
55 INT49436 Binding of TRPV1 145 0.48 38.35 55.08 5.00
56 INT14701 Negative_regulation of IFNA1 118 0.54 84.19 20.08 5.00
57 INT104395 Gene_expression of Cxcl9 83 0.76 73.1 19.79 5.00
58 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96 5.00
59 INT16321 Gene_expression of Cd3e 111 0.72 49.9 14.21 5.00
60 INT37722 Gene_expression of NCAM1 103 0.75 81.57 14.18 5.00
61 INT99780 Positive_regulation of Cxcl10 43 0.69 39.67 13.27 5.00
62 INT176607 Gene_expression of Cx3cl1 27 0.75 19.51 11.32 5.00
63 INT94465 Positive_regulation of Gene_expression of Hand1 43 0.38 29.76 10.88 5.00
64 INT111335 Gene_expression of HSPD1 57 0.75 55.51 10.38 5.00
65 INT99784 Positive_regulation of Cxcr3 22 0.66 22.44 10.36 5.00
66 INT168642 Gene_expression of Cx3cr1 15 0.77 21.73 8.1 5.00
67 INT104387 Positive_regulation of Cxcl9 24 0.67 22.26 7.87 5.00
68 INT24891 Gene_expression of SYP 55 0.75 45.76 7.53 5.00
69 INT174432 Transcription of Cxcr3 8 0.68 15.73 7.32 5.00
70 INT237051 Gene_expression of Cxcl11 24 0.64 25.74 5.77 5.00
71 INT66423 Binding of ELOVL1 52 0.40 61.63 5.16 5.00
72 INT104389 Positive_regulation of Gene_expression of Cxcl9 15 0.49 17.42 4.59 5.00
73 INT138916 Transcription of Cxcl9 13 0.68 9.88 3.96 5.00
74 INT127039 Negative_regulation of Ppig 13 0.21 5.29 3.87 5.00
75 INT47674 Positive_regulation of Myoz1 21 0.54 4.37 3.57 5.00
76 INT160409 Transcription of Cxcl10 9 0.65 7.95 3.53 5.00
77 INT5286 Gene_expression of ANTXR2 46 0.75 21.06 3.41 5.00
78 INT47949 Positive_regulation of ELOVL1 19 0.42 29.78 3.3 5.00
79 INT133374 Gene_expression of Pdha1 3 0.12 1.44 2.98 5.00
80 INT94463 Regulation of Gene_expression of Hand1 10 0.36 5.17 2.72 5.00
81 INT147582 Negative_regulation of AIS 13 0.37 13.26 2.46 5.00
82 INT170053 Binding of Cxcl9 5 0.46 6.34 2.43 5.00
83 INT220165 Positive_regulation of Cxcl11 8 0.60 9.67 2.29 5.00
84 INT73476 Transcription of MYC 18 0.69 12.14 2.13 5.00
85 INT138920 Regulation of Gene_expression of Cxcl10 5 0.59 5.72 2.1 5.00
86 INT105536 Regulation of Myoz1 6 0.17 3.45 2.01 5.00
87 INT92056 Transcription of Il12b 8 0.69 4.75 1.95 5.00
88 INT84512 Binding of Myoz1 7 0.30 4.48 1.7 5.00
89 INT73475 Positive_regulation of Transcription of MYC 7 0.67 5.46 1.66 5.00
90 INT153218 Positive_regulation of Transcription of Cxcl9 4 0.45 3.57 1.42 5.00
91 INT47950 Negative_regulation of ELOVL1 15 0.41 20.33 1.41 5.00
92 INT64952 Binding of HLA-DQA2 11 0.10 7.23 1.39 5.00
93 INT138913 Negative_regulation of Gene_expression of Cxcl9 8 0.58 6.22 1.36 5.00
94 INT138911 Negative_regulation of Cxcl9 5 0.42 3.31 1.35 5.00
95 INT252588 Transcription of Cxcl11 1 0.60 3.61 1.24 5.00
96 INT99325 Positive_regulation of Pdha1 6 0.49 1.55 1.22 5.00
97 INT237047 Positive_regulation of Gene_expression of Cxcl11 5 0.43 5.04 1.17 5.00
98 INT174447 Regulation of Cxcr3 1 0.60 2.68 1.12 5.00
99 INT99781 Positive_regulation of Negative_regulation of Cxcl10 2 0.50 0.97 0.8 5.00
100 INT185049 Transcription of Hand1 5 0.47 1.84 0.71 5.00
101 INT196866 Localization of Ppig 2 0.17 0.58 0.64 5.00
102 INT252587 Binding of Cxcl11 1 0.30 1.62 0.6 5.00
103 INT237990 Regulation of Gene_expression of Cxcl9 2 0.44 1.91 0.58 5.00
104 INT103782 Binding of Ppig 5 0.12 2.57 0.58 5.00
105 INT88870 Negative_regulation of PDXP 4 0.43 4.64 0.57 5.00
106 INT252586 Regulation of Transcription of Cxcl10 1 0.43 0.81 0.42 5.00
107 INT252585 Regulation of Cxcl11 1 0.51 0.95 0.41 5.00
108 INT252596 Positive_regulation of Binding of Cxcr3 1 0.49 1.19 0.41 5.00
109 INT252590 Regulation of Transcription of Hand1 1 0.36 0.76 0.36 5.00
110 INT252595 Regulation of Negative_regulation of Ppig 1 0.12 0.78 0.34 5.00
111 INT252581 Positive_regulation of Positive_regulation of Ppig 1 0.11 1.26 0.34 5.00
112 INT252589 Regulation of Negative_regulation of Cxcl10 1 0.43 0.77 0.34 5.00
113 INT239861 Gene_expression of Itga2 5 0.65 1.32 0.32 5.00
114 INT252592 Negative_regulation of Positive_regulation of Cxcl9 1 0.41 0.97 0.24 5.00
115 INT252591 Negative_regulation of Positive_regulation of Cxcl10 1 0.40 0.97 0.24 5.00
116 INT286429 Positive_regulation of Gene_expression of ANTXR2 2 0.25 1.46 0.23 5.00
117 INT252583 Positive_regulation of Binding of Ppig 1 0.12 0.46 0.16 5.00
118 INT252584 Positive_regulation of Transcription of Cxcl10 1 0.44 0.71 0.1 5.00
119 INT252593 Negative_regulation of Negative_regulation of Cxcl10 1 0.40 0.36 0.09 5.00
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