D:Lipodystrophy

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Disease Term
Synonyms CUTANEOUS LIPODYSTROPHY, Dystrophy Of Fatty Tissue, LIPOATROPHY, Lipodystrophies
Documents 154
Hot Single Events 122
Hot Interactions 5

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Lipodystrophy. They are ordered first by their relevance to Lipodystrophy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT273520 NBN Positive_regulation of CDIPT 1 0.06 0.82 0.08 100.00
2 INT274385 Binding of ABAT and CDIPT 1 0.00 1.21 0 94.72
3 INT283543 Binding of GARS and Setx 1 0.01 3.71 0 86.68
4 INT283542 Binding of SPG19 and Setx 1 0.06 3.69 0 86.68
5 INT283533 Binding of GARS and SPG19 1 0.00 1.72 0 80.48
6 INT127966 GPT Positive_regulation of SLC17A5 1 0.50 1.81 0.14 73.20
7 INT211576 Vldlr Positive_regulation of Lpl 1 0.38 0.24 0 70.40
8 INT182804 Binding of ETV3 and T2DM 1 0.10 2.62 0 69.92
9 INT182778 IGF1 Positive_regulation of Gene_expression of ETV3 1 0.03 1.89 0 67.04
10 INT182783 INS Positive_regulation of Gene_expression of ETV3 1 0.01 1.89 0 67.04
11 INT182777 IAPP Positive_regulation of Gene_expression of ETV3 1 0.06 1.88 0 67.04
12 INT182784 IGF1 Positive_regulation of Gene_expression of INS 1 0.02 1.87 0 65.28
13 INT182776 IAPP Positive_regulation of Gene_expression of INS 1 0.03 1.87 0 65.28
14 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 61.72
15 INT310275 Negative_regulation of Binding of Adipoq and Ins1 1 0.19 1.14 0.09 57.60
16 INT310274 Binding of Adipoq and Ins1 1 0.21 1.14 0.09 57.60
17 INT328309 GHS Positive_regulation of Localization of GH1 1 0.04 0.99 0.12 48.88
18 INT295439 Binding of AES and IFNA1 1 0.25 0.46 0.17 42.88
19 INT233303 Binding of CD4 and SRY 1 0.07 0.34 0.05 41.00
20 INT270044 Il10 Positive_regulation of Positive_regulation of Hmox1 1 0.20 1.59 0.53 25.00
21 INT270046 Ido1 Positive_regulation of Positive_regulation of Hmox1 1 0.15 0.8 0.27 25.00
22 INT283544 Binding of GARS and Bscl2 1 0.01 1.74 0 19.24
23 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
24 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3 5.00
25 INT295552 Binding of Ghrl and Ghsr 7 0.40 1.64 0.88 5.00
26 INT90387 ROS1 Positive_regulation of NFKB1 4 0.32 2.35 0.87 5.00
27 INT132318 Ghrl Positive_regulation of Localization of GH1 5 0.32 4.49 0.84 5.00
28 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 5.00
29 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77 5.00
30 INT152429 Ghrh Positive_regulation of Localization of Gh 4 0.37 0.56 0.75 5.00
31 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69 5.00
32 INT316546 Binding of GH1 and SST 2 0.03 0.55 0.54 5.00
33 INT328385 Binding of GHS and Ghrl 1 0.15 1.89 0.45 5.00
34 INT270043 Binding of Ldlr and Hdl1 1 0.01 2.3 0.43 5.00
35 INT323484 Ghsr Positive_regulation of Localization of Ins1 1 0.27 0.87 0.43 5.00
36 INT328377 Binding of GAST and Ghrl 1 0.03 0.62 0.43 5.00
37 INT323491 Olfr781 Positive_regulation of Localization of Ins1 1 0.01 0.87 0.4 5.00
38 INT316545 Binding of IGF1 and SST 1 0.06 0.45 0.37 5.00
39 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37 5.00
40 INT323502 Ghrl Positive_regulation of Localization of Ins1 1 0.15 1.58 0.33 5.00
41 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31 5.00
42 INT328299 Binding of GHRH and GHS 1 0.07 2.21 0.31 5.00
43 INT182771 ROS1 Positive_regulation of NFKB1 Positive_regulation of CRP 1 0.00 3.83 0.28 5.00
44 INT328378 GH1 Regulation of Gene_expression of Ghrl 1 0.02 0.39 0.25 5.00
45 INT328382 Positive_regulation of Ghrl Positive_regulation of Localization of INS 1 0.03 1.08 0.23 5.00
46 INT207845 Binding of INS and Hypism 3 0.04 2.88 0.22 5.00
47 INT241822 Binding of CD4 and HIVEP1 3 0.01 2.73 0.21 5.00
48 INT283373 Pcbd1 Regulation of RYR1 1 0.00 1.45 0.21 5.00
49 INT182634 Binding of CCR5 and MIP 2 0.39 1.29 0.2 5.00
50 INT328310 DBT Positive_regulation of Localization of GH1 1 0.00 0 0.19 5.00
51 INT274386 Binding of CD4 and ERVW-1 1 0.05 3.07 0.18 5.00
52 INT323494 Ghrl Regulation of Ins1 1 0.16 2.12 0.17 5.00
53 INT328386 GHS Positive_regulation of Localization of Ghrl 1 0.10 0.88 0.17 5.00
54 INT328379 Ghrl Positive_regulation of CRH 1 0.16 1.17 0.16 5.00
55 INT182772 ROS1 Positive_regulation of NFKB1 Positive_regulation of IL1B 1 0.00 1.89 0.14 5.00
56 INT182773 ROS1 Positive_regulation of NFKB1 Positive_regulation of IL6 1 0.00 1.9 0.14 5.00
57 INT182780 NFKB1 Positive_regulation of IL1B 1 0.00 1.8 0.14 5.00
58 INT182782 NFKB1 Positive_regulation of IL6 1 0.00 1.8 0.14 5.00
59 INT328374 GHRH Positive_regulation of Ghrl 1 0.13 0.26 0.13 5.00
60 INT328384 Ghrl Positive_regulation of ALPL 1 0.01 0.93 0.13 5.00
61 INT328313 Binding of CD36 and LDLR 1 0.00 0.63 0.11 5.00
62 INT283539 Binding of Litaf and Mad2l1bp 1 0.00 0.67 0.11 5.00
63 INT328294 GHS Positive_regulation of Localization of GHRH 1 0.10 0.12 0.11 5.00
64 INT328370 Binding of CD36 and Fabp1 1 0.01 0.64 0.11 5.00
65 INT328364 Binding of GHRH and Ghrl 1 0.09 0.2 0.1 5.00
66 INT328297 GHRH Positive_regulation of Transcription of GH1 1 0.04 0.26 0.1 5.00
67 INT328372 Ghrl Positive_regulation of Transcription of GH1 1 0.04 0.27 0.1 5.00
68 INT316543 GH1 Regulation of Gene_expression of IGF1 1 0.03 1.32 0.09 5.00
69 INT316552 Binding of SST and Sst1 1 0.03 0.53 0.09 5.00
70 INT182644 Binding of CXCR4 and Cxcr4 1 0.10 0.66 0.09 5.00
71 INT328311 Binding of GH1 and GHS 1 0.02 0.14 0.09 5.00
72 INT228333 Binding of IFNA1 and IRF9 2 0.04 0.53 0.09 5.00
73 INT328373 Negative_regulation of Ghrl Positive_regulation of Localization of GH1 1 0.05 0.31 0.08 5.00
74 INT300246 Binding of ABCB6 and HSR 1 0.11 1.86 0.08 5.00
75 INT147774 Binding of HLA-B and ABCB6 2 0.40 1.03 0.08 5.00
76 INT205119 Binding of HIVEP1 and GREM1 1 0.00 2.24 0.08 5.00
77 INT328302 Gene_expression of GHS Positive_regulation of Gene_expression of GH1 1 0.03 0.17 0.08 5.00
78 INT232897 Binding of Rab27a and SAMSN1 1 0.00 0.73 0.08 5.00
79 INT328306 GH1 Positive_regulation of Localization of INS 1 0.01 0.12 0.07 5.00
80 INT328366 GPR39 Regulation of Localization of Ghrl 1 0.11 0.2 0.07 5.00
81 INT323486 Ghrl Regulation of Localization of Ins1 1 0.21 2.07 0.07 5.00
82 INT323490 Ghsr Regulation of Ins1 1 0.26 0.54 0.07 5.00
83 INT232902 Binding of YWHAQ and Krt18 1 0.34 0.96 0.07 5.00
84 INT328380 AR Negative_regulation of Gene_expression of Ghrl 1 0.01 0.55 0.07 5.00
85 INT236932 Binding of Rxra and Pprc1 1 0.00 0.45 0.07 5.00
86 INT236936 Ppara Positive_regulation of Mapk1 1 0.09 0.64 0.07 5.00
87 INT232901 Regulation of Binding of YWHAQ and Krt18 1 0.41 0.96 0.07 5.00
88 INT236938 Binding of Akt1 and SPNS1 1 0.00 0.72 0.06 5.00
89 INT328305 GHS Positive_regulation of Localization of INS 1 0.02 0.07 0.05 5.00
90 INT328387 INS Negative_regulation of Gene_expression of Ghrl 1 0.01 0.6 0.05 5.00
91 INT323498 Ghsr Positive_regulation of Ins1 1 0.24 0.23 0.05 5.00
92 INT328371 Ghrl Negative_regulation of INS 1 0.03 0.13 0.05 5.00
93 INT328376 Ghrl Negative_regulation of SST 1 0.03 0.13 0.05 5.00
94 INT328383 Ghrl Negative_regulation of MBOAT4 1 0.26 0 0.05 5.00
95 INT328367 KISS1 Positive_regulation of Localization of Gnrh1 1 0.00 0 0.05 5.00
96 INT323482 Ghrl Negative_regulation of Ins1 1 0.13 0.24 0.05 5.00
97 INT328308 CRH Negative_regulation of KISS1 1 0.02 0 0.05 5.00
98 INT328292 KISS1 Positive_regulation of Localization of PLOD1 1 0.00 0 0.05 5.00
99 INT323503 STARD7 Positive_regulation of Ghrl 1 0.24 1.92 0.05 5.00
100 INT328293 Binding of JAG2 and GHS 1 0.03 0.09 0.05 5.00
101 INT328365 Binding of JAG2 and Ghrl 1 0.03 0.07 0.05 5.00
102 INT323485 Ghrl Negative_regulation of Localization of Ins1 1 0.15 1.99 0.05 5.00
103 INT182775 Binding of PTH and ROS1 1 0.04 1.73 0.04 5.00
104 INT328303 Gene_expression of GHS Positive_regulation of Gene_expression of GHRH 1 0.09 0.19 0.04 5.00
105 INT328301 GHRH Positive_regulation of SCG5 1 0.24 0.13 0.04 5.00
106 INT328363 Ghrl Negative_regulation of PLOD1 1 0.02 0.11 0.04 5.00
107 INT328295 GHRH Positive_regulation of GHS 1 0.10 0.13 0.04 5.00
108 INT328332 Ghrl Negative_regulation of Abo 1 0.01 0 0.04 5.00
109 INT323483 Slc2a2 Positive_regulation of Localization of Ins1 1 0.07 0.1 0.03 5.00
110 INT308540 CD4 Regulation of Localization of AGRP 1 0.39 0.85 0.03 5.00
111 INT328312 GHS Positive_regulation of Localization of PRL 1 0.02 0.21 0.03 5.00
112 INT334918 GNRH1 Positive_regulation of Gene_expression of FSHR 2 0.11 1.27 0.03 5.00
113 INT328362 LYPLA1 Regulation of Ghrl 1 0.04 0.07 0.03 5.00
114 INT323497 Negative_regulation of Ghsr Positive_regulation of Ins1 1 0.24 0 0.03 5.00
115 INT246480 Binding of ALB and SHBG 2 0.14 1.45 0.03 5.00
116 INT232900 Binding of ABR and Krt8 1 0.03 0.49 0.03 5.00
117 INT273519 NBN Negative_regulation of YOD1 1 0.03 0.56 0.03 5.00
118 INT274384 AGRP Negative_regulation of HIVEP1 1 0.00 0.77 0.03 5.00
119 INT328381 Ghrl Positive_regulation of NPY 1 0.06 0.15 0.03 5.00
120 INT328304 POMC Positive_regulation of Localization of CRH 1 0.07 0.22 0.03 5.00
121 INT328298 GHRH Negative_regulation of Localization of GHS 1 0.08 0.84 0 5.00
122 INT328369 Ghrl Negative_regulation of CRH 1 0.16 0.15 0 5.00
123 INT334921 GNRHR Positive_regulation of Gene_expression of CGA 1 0.01 0.53 0 5.00
124 INT300244 Binding of HLA-B and HSR 1 0.08 0.95 0 5.00
125 INT310280 Gpt Positive_regulation of SLPI 1 0.30 0.43 0 5.00
126 INT232890 Binding of Rab27a and Gopc 1 0.01 0.3 0 5.00
127 INT323489 Ghrl Regulation of Regulation of Ins1 1 0.09 0.07 0 5.00
128 INT334922 GNRHR Positive_regulation of Gene_expression of PLOD1 1 0.08 0.53 0 5.00
129 INT334919 GNRH1 Positive_regulation of Gene_expression of CGA 1 0.03 0.52 0 5.00
130 INT232899 Krt18 Negative_regulation of Binding of ABR 1 0.05 0.68 0 5.00
131 INT323493 Binding of Ins1 and Ghrl 1 0.12 1.25 0 5.00
132 INT211572 Binding of Kit and Pik3r1 1 0.21 0.06 0 5.00
133 INT233304 Binding of SRY and SLC22A8 1 0.34 0.93 0 5.00
134 INT283372 Binding of RYR1 and Pcbd1 1 0.00 0.28 0 5.00
135 INT310276 Gcg Positive_regulation of Localization of Ins1 1 0.25 0 0 5.00
136 INT232893 Binding of ABR and Nup62 1 0.03 0.13 0 5.00
137 INT236937 Map2k1 Negative_regulation of Ppara Positive_regulation of Itk 1 0.00 0.31 0 5.00
138 INT232895 Krt18 Positive_regulation of Gene_expression of ABR 1 0.46 0.09 0 5.00
139 INT211570 Kit Regulation of Gene_expression of Lpin1 1 0.27 0.12 0 5.00
140 INT273518 Binding of ALB and NBN 1 0.06 0.47 0 5.00
141 INT328296 GHRH Negative_regulation of Localization of GH1 1 0.03 0.84 0 5.00
142 INT283062 ERCC8 Positive_regulation of CFH 1 0.02 1.88 0 5.00
143 INT323499 Ghrl Positive_regulation of Ins1 1 0.21 0.25 0 5.00
144 INT328375 Ghrl Negative_regulation of LEP 1 0.07 0.15 0 5.00
145 INT334917 GNRHR Positive_regulation of Gene_expression of FSHR 1 0.05 0.53 0 5.00
146 INT323492 Ins1 Regulation of Gene_expression of Pck1 1 0.08 0.16 0 5.00
147 INT211574 Regulation of Binding of Kit and Pik3r1 1 0.16 0.06 0 5.00
148 INT232898 Binding of KRT1 and Krt8 1 0.27 1.22 0 5.00
149 INT310279 Tmprss11d Positive_regulation of SLPI 1 0.18 0.43 0 5.00
150 INT323500 Ghrl Positive_regulation of Grb2 1 0.13 0.5 0 5.00
151 INT211573 Positive_regulation of Binding of Dbp and Stip1 1 0.00 0.38 0 5.00
152 INT232896 Krt8 Negative_regulation of Binding of ABR 1 0.04 0.68 0 5.00
153 INT211577 Vldlr Regulation of Gene_expression of Lpin1 1 0.27 0.12 0 5.00
154 INT274387 Binding of POLA1 and IGSF9 1 0.01 0.58 0 5.00
155 INT182774 Binding of ETV3 and SAE1 1 0.00 1.17 0 5.00
156 INT232892 Krt18 Positive_regulation of Gene_expression of Krt8 1 0.30 0.09 0 5.00
157 INT323495 Ghrl Positive_regulation of Irs1 1 0.20 0.5 0 5.00
158 INT323487 Ghrl Positive_regulation of Phosphorylation of Akt1 1 0.09 0.77 0 5.00
159 INT283061 Binding of ERCC8 and LDLR 1 0.00 0.44 0 5.00
160 INT328368 Ghrl Positive_regulation of INS 1 0.04 0.22 0 5.00
161 INT232889 Binding of Krt18 and Krt8 1 0.22 1.09 0 5.00
162 INT306764 Binding of Aes and ZMYND10 1 0.04 0.21 0 5.00
163 INT323496 Binding of Rip and Ghsr 1 0.08 0.34 0 5.00
164 INT275190 Localization of CD4 Positive_regulation of Positive_regulation of LCK 1 0.10 0.99 0 5.00
165 INT211571 Pik3r1 Positive_regulation of Gene_expression of Kit 1 0.30 0.3 0 5.00
166 INT336169 Binding of HIVEP1 and CXCR4 1 0.01 0.44 0 5.00
167 INT232894 Binding of ABR and Rab27a 1 0.08 0.3 0 5.00
168 INT236933 Ppara Positive_regulation of Itk 1 0.01 0.31 0 5.00
169 INT334920 GNRH1 Positive_regulation of Gene_expression of PLOD1 1 0.16 0.52 0 5.00
170 INT336168 Binding of CCR5 and HIVEP1 1 0.01 0.44 0 5.00
171 INT214922 Binding of MDM2 and TP53 1 0.08 1.55 0 5.00
172 INT211578 Binding of Dbp and Stip1 1 0.00 0.38 0 5.00
173 INT236935 Negative_regulation of Ppara Positive_regulation of Itk 1 0.01 0.31 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Lipodystrophy. They are ordered first by their pain relevance and then by number of times they were reported in Lipodystrophy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT211548 Gene_expression of Lpin1 9 0.76 12.83 0.96 100.00
2 INT28861 Binding of Gh 61 0.46 25.61 6.38 100.00
3 INT237337 Binding of Cav3 3 0.44 2.63 0.11 100.00
4 INT300717 Gene_expression of Ptrf 1 0.61 3.64 0.18 99.96
5 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 99.88
6 INT167270 Negative_regulation of Gene_expression of Lep 13 0.55 5.48 1.19 99.82
7 INT165690 Localization of Abcc2 4 0.79 1.31 1.38 99.68
8 INT130299 Gene_expression of Abcc2 2 0.58 0.61 0.95 99.68
9 INT260849 Gene_expression of NBN 9 0.67 7.11 0.16 99.66
10 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12 99.56
11 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 99.52
12 INT122584 Negative_regulation of Gene_expression of PPARA 56 0.58 37.61 9.76 99.48
13 INT127435 Gene_expression of Per1 89 0.77 13.94 22.31 99.36
14 INT139254 Negative_regulation of Per1 12 0.56 3.17 1.62 99.36
15 INT211534 Localization of Abcb11 2 0.61 0.15 0.18 99.08
16 INT176176 Gene_expression of Abcb11 2 0.58 0.45 0.1 99.08
17 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 99.06
18 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 99.04
19 INT212171 Gene_expression of CDIPT 5 0.37 2.58 2.92 98.96
20 INT29879 Positive_regulation of GGH 9 0.70 3.13 2.62 98.94
21 INT220506 Binding of Cav1 13 0.45 5.46 0.38 98.84
22 INT111488 Gene_expression of HAS1 56 0.77 32.6 15.29 98.60
23 INT226105 Regulation of Ghrl 10 0.50 2.36 2.26 98.60
24 INT231412 Positive_regulation of NBN 3 0.55 3.13 0.07 98.22
25 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53 97.76
26 INT334926 Positive_regulation of MEHMO 1 0.02 10.11 2.37 97.64
27 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 97.58
28 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 97.52
29 INT211551 Gene_expression of Cyp8b1 1 0.69 0.31 0.1 97.36
30 INT211530 Localization of Cyp8b1 1 0.63 0.15 0.05 97.36
31 INT300718 Negative_regulation of Ptrf 1 0.34 4.1 0.18 97.16
32 INT211553 Gene_expression of Pltp 2 0.48 0.96 0.3 97.04
33 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 97.00
34 INT26974 Negative_regulation of Adipoq 27 0.52 26.01 2.59 96.32
35 INT211562 Positive_regulation of Gene_expression of Lpin1 1 0.49 0.27 0 96.24
36 INT63057 Regulation of CYP3A4 31 0.61 5.75 6.92 96.16
37 INT211560 Localization of Mttp 1 0.66 0.15 0.05 95.88
38 INT211547 Gene_expression of Mttp 1 0.40 0.74 0.05 95.88
39 INT198884 Gene_expression of Vldlr 13 0.70 2.41 0.44 95.80
40 INT194465 Gene_expression of Ldlr 27 0.76 31.36 2.73 95.80
41 INT211556 Localization of Pltp 1 0.56 0.15 0.05 95.64
42 INT198879 Localization of Vldlr 6 0.39 0.58 1.1 95.40
43 INT198904 Localization of Lrp1 11 0.62 3.25 1.01 95.40
44 INT211552 Localization of Scarb1 3 0.60 1.27 0.17 95.40
45 INT211532 Localization of Ldlr 4 0.56 3.52 0.13 95.40
46 INT211529 Localization of Lpl 1 0.63 0.15 0.05 95.40
47 INT211537 Localization of Lipc 1 0.61 0.15 0.05 95.40
48 INT211569 Localization of SH2D2A 1 0.68 0.15 0.05 95.40
49 INT211561 Localization of Srebf2 1 0.71 0.15 0.05 95.40
50 INT211566 Localization of LIPC 3 0.61 2.31 0.05 95.40
51 INT203953 Localization of Srebf1 3 0.62 1.15 0.05 95.40
52 INT249 Localization of GHRH 215 0.80 78.02 51.87 94.72
53 INT148107 Binding of CDIPT 8 0.17 4.56 0.53 94.72
54 INT176217 Gene_expression of Srebf2 2 0.53 0.43 0.05 94.68
55 INT952 Negative_regulation of GHRH 57 0.56 25.3 10.34 94.56
56 INT18323 Negative_regulation of Localization of Ins1 122 0.58 45.74 23.04 94.36
57 INT176174 Gene_expression of Srebf1 16 0.66 6.53 0.82 94.36
58 INT211568 Gene_expression of SH2D2A 1 0.26 0.16 0.05 94.04
59 INT3216 Positive_regulation of Localization of Ins1 170 0.69 56.78 35.63 93.76
60 INT155218 Binding of ABCB6 18 0.35 13.93 2.25 93.60
61 INT3913 Positive_regulation of ABAT 47 0.69 22.73 33.4 93.52
62 INT135920 Binding of SRY 9 0.45 3.57 1.45 93.32
63 INT3214 Localization of Ins1 527 0.80 196.9 79.26 93.32
64 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46 93.20
65 INT311977 Regulation of Negative_regulation of IFNA1 3 0.13 1.79 0.64 93.04
66 INT224964 Localization of Ghrl 30 0.59 7.71 8.77 92.96
67 INT132411 Positive_regulation of Ghrl 25 0.69 12.05 2.59 92.96
68 INT185246 Gene_expression of Psmd1 26 0.50 8.89 3.73 92.64
69 INT14701 Negative_regulation of IFNA1 118 0.54 84.19 20.08 92.56
70 INT36287 Binding of CD4 96 0.47 58.93 11.88 92.52
71 INT283541 Binding of GARS 1 0.01 3.33 0.04 92.36
72 INT197599 Transcription of Rb1 4 0.63 0.87 0.3 92.20
73 INT245909 Positive_regulation of Transcription of Rb1 1 0.05 0.49 0.04 92.20
74 INT194479 Phosphorylation of Ppara 47 0.81 30.36 6.6 91.92
75 INT147909 Gene_expression of Lpl 21 0.58 9.35 1.14 91.88
76 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 91.84
77 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 91.72
78 INT211567 Gene_expression of LIPC 1 0.09 1.55 0.05 91.68
79 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 91.52
80 INT264641 Binding of AES 25 0.42 18.56 6.98 91.48
81 INT211555 Gene_expression of Lipc 1 0.52 0.16 0.05 91.44
82 INT156416 Gene_expression of Lipg 38 0.67 18.35 4.07 91.20
83 INT198885 Gene_expression of Lrp1 33 0.57 10.2 1.91 90.84
84 INT211557 Gene_expression of Scarb1 30 0.75 5.03 0.94 90.60
85 INT17562 Negative_regulation of Lipg 32 0.51 16.91 3.17 89.60
86 INT1928 Negative_regulation of Lpl 18 0.51 11.22 2.49 89.60
87 INT190363 Positive_regulation of Negative_regulation of PPARA 10 0.44 4.8 0.87 88.36
88 INT182800 Positive_regulation of ETV3 5 0.46 10.01 0.14 88.36
89 INT182754 Positive_regulation of T2DM 1 0.67 4.5 0.03 88.36
90 INT170208 Negative_regulation of Lpl 15 0.49 6.07 0.45 88.16
91 INT245901 Positive_regulation of Dlk1 1 0.25 0.48 0.04 87.92
92 INT115659 Gene_expression of ABCB6 29 0.75 13.59 1.43 87.80
93 INT233314 Positive_regulation of Binding of SRY 1 0.41 0.28 0 87.72
94 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41 87.56
95 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 87.40
96 INT188242 Negative_regulation of Positive_regulation of CRP 4 0.23 3.94 0.22 87.40
97 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 87.00
98 INT211543 Regulation of Lpin1 1 0.60 0.28 0 86.84
99 INT283536 Binding of Setx 1 0.36 3.69 0 86.68
100 INT158409 Gene_expression of T2DM 3 0.65 9.58 0.56 86.56
101 INT124185 Negative_regulation of Kit 57 0.59 35.43 3.61 86.52
102 INT188241 Negative_regulation of ADIPOQ 16 0.43 22.16 1.47 86.40
103 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77 86.40
104 INT121834 Gene_expression of IAPP 24 0.66 20.96 0.26 86.36
105 INT310273 Negative_regulation of Acaca 1 0.19 1.08 0.07 86.08
106 INT190360 Negative_regulation of Protein_catabolism of PPARA 1 0.11 0.18 0 85.52
107 INT163262 Transcription of ADIPOQ 5 0.52 2.81 0.14 85.08
108 INT245905 Negative_regulation of Transcription of ADIPOQ 1 0.42 1.26 0.05 85.08
109 INT190361 Protein_catabolism of PPARA 12 0.97 3.01 0.87 85.04
110 INT300720 Localization of Ptrf 1 0.59 1.57 0.03 84.76
111 INT194462 Localization of Ppara 94 0.78 68.33 12.09 84.72
112 INT343449 Gene_expression of Upp1 1 0.22 1.05 0.07 84.28
113 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 84.20
114 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87 84.00
115 INT211531 Negative_regulation of Gene_expression of Vldlr 1 0.38 0.21 0.04 82.80
116 INT28817 Binding of TRPV4 6 0.39 3.92 2.59 82.24
117 INT211545 Negative_regulation of Gene_expression of Lpin1 1 0.42 0.38 0 81.84
118 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 81.68
119 INT10763 Localization of IL2 157 0.80 81.11 33.21 81.56
120 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32 80.76
121 INT17890 Negative_regulation of HMGCR 26 0.42 12.05 1.94 80.52
122 INT181829 Binding of Ppargc1a 16 0.48 9.61 0.34 80.44
123 INT163747 Negative_regulation of Cav3 3 0.54 0.56 1.16 79.96
124 INT136488 Regulation of LMNA 13 0.60 3.53 0.2 79.16
125 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 77.68
126 INT73925 Regulation of FBL 3 0.22 2.19 0.31 77.44
127 INT330750 Regulation of OR1E1 1 0.05 3.2 0.09 77.16
128 INT86023 Transcription of PPARA 60 0.66 25.8 5.7 76.64
129 INT211538 Negative_regulation of Lpin1 1 0.57 1.28 0.04 76.08
130 INT60252 Binding of HIVEP1 59 0.32 65.12 5.06 75.92
131 INT233311 Positive_regulation of Gene_expression of SRY 1 0.41 0.61 0.06 75.84
132 INT207727 Positive_regulation of SRY 2 0.56 1.94 0.03 75.84
133 INT300714 Positive_regulation of Gene_expression of Ptrf 1 0.55 1.16 0.04 75.36
134 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 75.20
135 INT121678 Gene_expression of SRY 15 0.68 5.61 0.06 75.16
136 INT11957 Negative_regulation of LPA 52 0.59 39.09 6.84 75.00
137 INT13063 Binding of RHCE 16 0.38 6.54 1.22 75.00
138 INT68708 Negative_regulation of RHCE 4 0.26 2.53 0.48 75.00
139 INT162058 Binding of GGH 8 0.37 3.45 0.2 75.00
140 INT158542 Gene_expression of HTN1 10 0.75 10.69 1.07 74.84
141 INT158541 Positive_regulation of Gene_expression of HTN1 3 0.40 5.88 0.97 74.84
142 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43 74.36
143 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 73.80
144 INT156739 Localization of SRY 2 0.75 3.21 0.03 73.28
145 INT233309 Regulation of Localization of SRY 1 0.37 0.33 0 73.28
146 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 73.20
147 INT81795 Negative_regulation of AGRP 23 0.41 10.93 0.87 73.04
148 INT77281 Negative_regulation of HIVEP1 132 0.49 102.78 5.36 72.80
149 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 71.84
150 INT141791 Regulation of Ucp3 3 0.53 1.27 0.28 70.72
151 INT245910 Regulation of Ucp2 1 0.12 0.93 0.04 70.72
152 INT245906 Regulation of Transcription of Ucp2 1 0.12 0.93 0.04 70.72
153 INT245908 Regulation of Transcription of Ucp3 1 0.09 0.92 0.04 70.72
154 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55 70.20
155 INT182787 Binding of ETV3 14 0.37 25.44 0.37 69.92
156 INT131019 Binding of T2DM 6 0.47 6.97 0.31 69.92
157 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 69.76
158 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 69.76
159 INT112089 Gene_expression of Cav1 73 0.75 23.8 1.97 69.68
160 INT245907 Transcription of Ucp3 2 0.63 0.99 0.04 69.68
161 INT62487 Localization of HIVEP1 35 0.73 36.24 2.72 69.68
162 INT233322 Negative_regulation of Localization of HIVEP1 4 0.10 6.1 0.57 69.68
163 INT252 Localization of GH1 529 0.80 227.4 122.05 69.52
164 INT151387 Gene_expression of Cav3 14 0.78 4 5.31 68.84
165 INT261186 Positive_regulation of Niacr1 6 0.49 5.28 1.81 68.16
166 INT228578 Transcription of Ucp2 2 0.29 1.19 0.04 68.00
167 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 67.92
168 INT15648 Positive_regulation of RYR1 30 0.67 12.03 3.26 67.80
169 INT34057 Negative_regulation of Gene_expression of IFNA1 65 0.58 43.46 17.25 67.56
170 INT67332 Negative_regulation of ITGA4 8 0.51 7.95 2.14 67.12
171 INT182788 Gene_expression of ETV3 8 0.40 11.33 0.36 67.04
172 INT211539 Regulation of Transcription of Tpp1 1 0.44 0.07 0.03 66.28
173 INT211542 Transcription of Tpp1 1 0.51 0.07 0.03 66.28
174 INT232882 Transcription of ABR 1 0.09 0.61 0 65.72
175 INT214975 Localization of Cav1 7 0.75 2.7 0.13 64.56
176 INT140175 Regulation of Kit 23 0.62 8.59 1.79 64.48
177 INT109569 Regulation of Om 4 0.04 0.12 0.22 64.48
178 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 64.40
179 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 64.08
180 INT812 Localization of INS 1026 0.81 515.6 145.31 63.64
181 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 63.36
182 INT100144 Negative_regulation of Positive_regulation of PPARA 17 0.49 12.71 2.68 63.36
183 INT12618 Positive_regulation of IAPP 54 0.68 32.03 2.29 63.20
184 INT129762 Binding of HTN1 5 0.03 5.68 0.19 63.20
185 INT186135 Negative_regulation of Binding of ITGAL 5 0.34 3.27 0.74 62.24
186 INT107315 Negative_regulation of CCR5 22 0.57 13.82 6.11 62.08
187 INT80549 Binding of ICAM1 53 0.47 42.76 9.72 61.72
188 INT87322 Binding of ITGAL 23 0.47 15.73 4.68 61.72
189 INT756 Gene_expression of C3 138 0.75 100.6 19.2 61.60
190 INT122196 Gene_expression of TAL1 5 0.47 2.07 0.63 60.80
191 INT188756 Positive_regulation of AGRP 43 0.60 23.67 2.51 60.60
192 INT211559 Regulation of Lipc 1 0.20 0.22 0 60.56
193 INT3959 Regulation of Lipg 6 0.27 2.48 0.29 60.08
194 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 60.00
195 INT197167 Positive_regulation of Localization of Ppara 18 0.67 9.51 1.21 60.00
196 INT28739 Binding of Ins1 35 0.37 22.43 2.14 59.44
197 INT300711 Localization of Cav3 1 0.69 1.17 0.04 59.44
198 INT300719 Regulation of Binding of Cav3 1 0.25 1.17 0.04 59.44
199 INT300721 Regulation of Localization of Cav3 1 0.41 1.17 0.04 59.44
200 INT425 Localization of PRL 455 0.81 189.64 144.8 59.12
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