D:Lipoma

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Disease Term
Synonyms Fatty Tumor, Fatty Tumors, FATTY TUMOUR, Fatty Tumours, HIBERNOMA, HIBERNOMAS, LIPOMA PLEOMORPHIC, LIPOMAS, Lipomas Pleomorphic, Pleomorphic Lipoma, Pleomorphic Lipomas
Documents 589
Hot Single Events 37
Hot Interactions 8

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Lipoma. They are ordered first by their relevance to Lipoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT350147 Binding of LPP and SH2B3 1 0.36 1.82 0.55 100.00
2 INT350144 Binding of LPP and NAA25 1 0.25 1.83 0.55 100.00
3 INT350150 Binding of LPP and ATXN2 1 0.35 1.82 0.54 100.00
4 INT350148 Binding of IL12A and ERAL1 1 0.21 8.23 2.26 94.60
5 INT286113 Binding of Fap and Rpe65 1 0.04 1.97 0 84.00
6 INT286110 Binding of Rpe65 and Gopc 1 0.01 1.97 0 84.00
7 INT350151 Binding of SNRNP70 and SH2B3 1 0.13 1.22 0.2 83.00
8 INT350152 Binding of ATXN2 and SNRNP70 1 0.13 1.22 0.2 83.00
9 INT350149 SH2B3 Regulation of CD8A 1 0.13 0.86 0.17 59.20
10 INT350145 Binding of SNRNP70 and ERAL1 1 0.05 1.29 0.28 40.88
11 INT350146 Binding of IL12A and RS1 1 0.01 0.97 0.23 21.36
12 INT239573 Binding of DPF1 and AIS 1 0.02 0.74 0.31 5.00
13 INT239570 Binding of PDGFC and AIS 1 0.04 0.9 0.26 5.00
14 INT239572 DPF1 Positive_regulation of AIS 1 0.02 0.71 0.24 5.00
15 INT197811 Binding of SMS and SST 1 0.00 0.98 0.21 5.00
16 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19 5.00
17 INT239571 Binding of PDGFC and IGSF10 1 0.00 0.34 0.08 5.00
18 INT197808 Binding of MEN1 and NME1 1 0.00 1.81 0 5.00
19 INT304029 Binding of PTEN and TP53 1 0.35 0.62 0 5.00
20 INT304020 AR Regulation of TP53 1 0.24 1.11 0 5.00
21 INT197809 Binding of MEN1 and VIM 1 0.04 0.52 0 5.00
22 INT286114 Binding of MSH6 and Mutyh 1 0.17 0 0 5.00
23 INT197810 Binding of MEN1 and MUC1 1 0.06 0.47 0 5.00
24 INT304022 Binding of PIK3CG and TP53 1 0.10 0.72 0 5.00
25 INT197816 Binding of MEN1 and NFKB1 1 0.05 0.07 0 5.00
26 INT286111 Binding of Rpa3 and Mutyh 1 0.30 0 0 5.00
27 INT197813 Binding of AMBP and MEN1 1 0.00 0.51 0 5.00
28 INT304028 MDM2 Regulation of TP53 1 0.19 1.11 0 5.00
29 INT304014 Binding of MSI1 and SGCG 1 0.00 1.92 0 5.00
30 INT304012 Binding of AKT1 and PIK3CA 1 0.28 1.14 0 5.00
31 INT197812 Binding of AMBP and RDBP 1 0.00 0.51 0 5.00
32 INT304018 Regulation of Binding of PIK3CG and TP53 1 0.12 0.73 0 5.00
33 INT286112 Binding of Apc and Afap1 1 0.05 0.71 0 5.00
34 INT304025 Binding of PIK3CA and TP53 1 0.30 0.67 0 5.00
35 INT286115 Binding of APEX1 and Mutyh 1 0.10 0 0 5.00
36 INT197817 Binding of JUND and MEN1 1 0.18 0.14 0 5.00
37 INT304015 Binding of PIK3CA and PIK3CG 1 0.09 0.67 0 5.00
38 INT286444 PCSK9 Positive_regulation of Apob 1 0.02 0.49 0 5.00
39 INT197844 Binding of MEN1 and Nfkb1 1 0.06 0.26 0 5.00
40 INT256632 Binding of PTCH1 and Jkamp 1 0.00 2.32 0 5.00
41 INT304019 Binding of AKT1 and TP53 1 0.27 0.72 0 5.00
42 INT304026 Binding of PIK3CG and PTEN 1 0.11 0.62 0 5.00
43 INT242102 Nkx2-1 Regulation of Gene_expression of Ttf1 1 0.00 1.55 0 5.00
44 INT193193 Binding of CRS and RAPH1 1 0.12 1.47 0 5.00
45 INT197815 Binding of MEN1 and TGFB1 1 0.16 0.13 0 5.00
46 INT304027 Negative_regulation of PTEN Positive_regulation of Positive_regulation of AKT1 1 0.32 1.86 0 5.00
47 INT286109 Binding of Pcna and Mutyh 1 0.30 0 0 5.00
48 INT304017 Regulation of Binding of AKT1 and TP53 1 0.32 0.73 0 5.00
49 INT304023 SFRP1 Regulation of Binding of MSI1 1 0.04 1.78 0 5.00
50 INT304016 SFRP4 Regulation of Binding of MSI1 1 0.04 1.78 0 5.00
51 INT197814 Binding of MEN1 and RELA 1 0.42 0.07 0 5.00
52 INT304013 Binding of SUZ12 and JAZF1 1 0.30 1.89 0 5.00
53 INT304024 Binding of AKT1 and PTEN 1 0.33 1.08 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Lipoma. They are ordered first by their pain relevance and then by number of times they were reported in Lipoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT81262 Positive_regulation of Phlda2 9 0.43 3.76 2.47 100.00
2 INT188741 Binding of ACTG2 3 0.20 3.27 0 99.62
3 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 99.60
4 INT28084 Positive_regulation of VIM 49 0.67 35.12 5.15 99.60
5 INT82796 Regulation of CDKN1A 22 0.53 9.83 3.33 99.60
6 INT124944 Regulation of KIT 15 0.60 11.84 0.24 99.60
7 INT207767 Positive_regulation of CALB2 1 0.08 0.65 0 99.60
8 INT194993 Binding of RB1 15 0.37 10.96 0.4 99.52
9 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 99.44
10 INT49610 Positive_regulation of Gene_expression of CTS 7 0.43 7.45 3.58 99.32
11 INT350153 Binding of SH2B3 1 0.34 4.41 1.19 99.26
12 INT350157 Binding of ATXN2 1 0.33 3.53 1.02 99.26
13 INT350155 Binding of NAA25 1 0.23 1.8 0.54 99.26
14 INT19763 Gene_expression of CTs 69 0.78 32.92 18.87 99.16
15 INT197832 Localization of MEN1 1 0.80 11.01 0.63 99.14
16 INT246502 Negative_regulation of Men1 2 0.30 8.9 0.33 98.76
17 INT4047 Binding of F13A1 105 0.43 66.54 11.81 95.08
18 INT182809 Negative_regulation of Binding of Cuzd1 1 0.28 0.47 0.1 92.88
19 INT182806 Binding of Cuzd1 3 0.24 1.45 0.53 92.12
20 INT197828 Negative_regulation of MEN1 1 0.43 5.06 0.06 91.48
21 INT68565 Gene_expression of Fap 14 0.57 24.39 1.14 91.36
22 INT118217 Regulation of Cuzd1 2 0.30 2.36 0.91 91.16
23 INT197841 Positive_regulation of MEN1 1 0.41 2.38 0 89.84
24 INT300623 Positive_regulation of Men1 1 0.35 10.65 0.57 89.00
25 INT162801 Localization of CALR 7 0.73 8.69 0.6 88.40
26 INT182807 Localization of Cuzd1 2 0.49 1.38 0.14 88.32
27 INT182808 Phosphorylation of Cuzd1 1 0.53 0.38 0 88.32
28 INT182810 Gene_expression of Cuzd1 5 0.44 1.49 0.53 87.40
29 INT296652 Protein_catabolism of MCPH1 1 0.56 1.65 0 86.28
30 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 85.00
31 INT169180 Binding of SNRNP70 204 0.47 119.1 29.3 83.00
32 INT8477 Negative_regulation of AFP 35 0.58 31.52 3.1 82.96
33 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 82.52
34 INT94454 Gene_expression of CD68 73 0.72 63.94 10.43 82.52
35 INT6810 Gene_expression of ENO2 70 0.78 54.8 8.35 82.52
36 INT74520 Positive_regulation of CD68 30 0.61 31.68 7.59 82.28
37 INT15652 Positive_regulation of ENO2 37 0.68 33.39 5.02 82.28
38 INT208427 Regulation of T 3 0.25 3.28 1.08 78.96
39 INT114499 Gene_expression of MCPH1 38 0.67 26.68 4.55 77.56
40 INT350156 Positive_regulation of SH2B3 1 0.48 1.04 0.15 74.92
41 INT146300 Binding of RS1 31 0.22 29.55 3.04 68.88
42 INT36354 Localization of CTs 26 0.64 20.84 9.31 67.44
43 INT25356 Positive_regulation of S100A12 18 0.69 17.62 3.38 64.96
44 INT99176 Positive_regulation of Fap 4 0.13 7.5 0.22 64.40
45 INT345972 Binding of HGD 1 0.02 1.95 0.08 64.20
46 INT193196 Regulation of MNX1 2 0.19 2.53 0.64 63.80
47 INT85085 Positive_regulation of KIT 36 0.53 30.08 2.17 62.48
48 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07 60.04
49 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 59.84
50 INT156595 Gene_expression of CDX2 10 0.69 7.8 0.25 59.48
51 INT172370 Binding of MCPH1 6 0.34 4.75 0.13 57.72
52 INT114498 Positive_regulation of MCPH1 10 0.43 5.82 0.91 56.64
53 INT159232 Negative_regulation of SYP 4 0.41 4.45 0.38 55.88
54 INT82374 Binding of SYP 13 0.36 13.69 0.85 55.36
55 INT119818 Negative_regulation of CHGA 10 0.57 8.21 2.04 53.32
56 INT10893 Binding of VWF 27 0.47 25.02 2.82 52.36
57 INT169677 Gene_expression of PEAK1 1 0.04 1.1 0 47.60
58 INT301374 Localization of Stk11 1 0.23 1.58 0 44.88
59 INT73627 Binding of Fap 8 0.36 11.14 0.4 44.84
60 INT197839 Negative_regulation of PHPT1 1 0.04 2.88 0.06 42.12
61 INT626 Localization of CALCA 289 0.81 125.39 221.15 41.92
62 INT98251 Binding of IL12A 20 0.37 16.03 4.51 41.68
63 INT331656 Localization of TRIM6-TRIM34 1 0.53 1.69 0.12 41.44
64 INT443 Localization of POMC 1020 0.81 284.52 443.17 40.96
65 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 39.68
66 INT197842 Gene_expression of PHPT1 1 0.06 5.89 0.16 39.52
67 INT197835 Positive_regulation of Gene_expression of PHPT1 1 0.04 3.17 0.07 39.52
68 INT61102 Gene_expression of MEN1 12 0.78 17.7 0.43 39.20
69 INT197836 Positive_regulation of Gene_expression of MEN1 1 0.50 3.16 0.07 39.20
70 INT6512 Gene_expression of PTH 103 0.77 76.29 6.33 37.20
71 INT6514 Positive_regulation of Gene_expression of PTH 28 0.67 30.28 1.37 37.20
72 INT73731 Binding of RAPH1 9 0.33 14.58 0.5 35.68
73 INT223323 Transcription of SNRNP70 4 0.67 3.03 1.7 35.60
74 INT350154 Transcription of RS1 1 0.01 0.8 0.3 35.60
75 INT242822 Transcription of Fap 1 0.18 1.2 0 33.84
76 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 32.56
77 INT207443 Binding of ERAL1 5 0.19 3.69 1.47 29.08
78 INT95636 Gene_expression of ACTG2 23 0.44 19.87 1.75 27.40
79 INT246524 Binding of QPCT 4 0.05 3.65 0.72 21.68
80 INT20420 Gene_expression of MYC 99 0.75 49.32 14.36 21.40
81 INT20421 Positive_regulation of MYC 19 0.67 10.43 1.9 21.28
82 INT44378 Gene_expression of GSTM1 69 0.76 34.61 8.81 20.64
83 INT193195 Localization of MNX1 1 0.59 1.01 0.03 19.80
84 INT6868 Gene_expression of GFAP 136 0.78 84.65 22.7 17.12
85 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 16.60
86 INT59784 Binding of DES 22 0.47 19.48 2.27 16.00
87 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 10.00
88 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 10.00
89 INT158 Localization of Prl 2431 0.81 378.96 952.2 5.00
90 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 5.00
91 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 5.00
92 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
93 INT1893 Localization of Gh 1041 0.79 340.23 256.58 5.00
94 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 5.00
95 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 5.00
96 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 5.00
97 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 5.00
98 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
99 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
100 INT425 Localization of PRL 455 0.81 189.64 144.8 5.00
101 INT252 Localization of GH1 529 0.80 227.4 122.05 5.00
102 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
103 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 5.00
104 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
105 INT397 Localization of SST 232 0.81 58.05 101.19 5.00
106 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 5.00
107 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
108 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 5.00
109 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
110 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
111 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 5.00
112 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56 5.00
113 INT3933 Positive_regulation of PLOD1 128 0.70 30.76 42.03 5.00
114 INT5793 Binding of CTS 110 0.48 63.91 40.62 5.00
115 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
116 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
117 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 5.00
118 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
119 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 5.00
120 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 5.00
121 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 5.00
122 INT9292 Positive_regulation of SGCG 93 0.67 35.13 23.48 5.00
123 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42 5.00
124 INT11157 Binding of EGF 88 0.48 53.73 21.25 5.00
125 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94 5.00
126 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61 5.00
127 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 5.00
128 INT1578 Negative_regulation of Localization of PRL 52 0.59 20.62 17.18 5.00
129 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 5.00
130 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 5.00
131 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 5.00
132 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 5.00
133 INT2243 Localization of GAST 67 0.81 34.54 16.19 5.00
134 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59 5.00
135 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 5.00
136 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 5.00
137 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99 5.00
138 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 5.00
139 INT14572 Binding of INS 205 0.48 175.43 13.38 5.00
140 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 5.00
141 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 5.00
142 INT65058 Binding of Nfkb1 36 0.45 19.87 10.02 5.00
143 INT38564 Binding of AIS 36 0.38 27.77 9.31 5.00
144 INT6510 Gene_expression of AFP 130 0.78 119.2 9.19 5.00
145 INT128159 Positive_regulation of DDIT3 29 0.67 29.5 8.99 5.00
146 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57 5.00
147 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36 5.00
148 INT108202 Positive_regulation of PIK3CG 47 0.67 25.83 8.25 5.00
149 INT2093 Gene_expression of GAST 50 0.78 32.32 7.98 5.00
150 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 5.00
151 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 5.00
152 INT79168 Binding of TNC 39 0.47 16.51 7.55 5.00
153 INT24891 Gene_expression of SYP 55 0.75 45.76 7.53 5.00
154 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 5.00
155 INT26462 Gene_expression of DNAH8 44 0.78 19.36 7.31 5.00
156 INT6511 Positive_regulation of AFP 76 0.70 70.15 7.28 5.00
157 INT30443 Positive_regulation of AIS 30 0.54 22.59 7.2 5.00
158 INT147583 Gene_expression of AIS 82 0.58 48.7 7.11 5.00
159 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63 5.00
160 INT25022 Binding of PAEP 66 0.42 22.83 6.59 5.00
161 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02 5.00
162 INT2890 Positive_regulation of MB 39 0.70 29.58 6.01 5.00
163 INT38671 Positive_regulation of KRT20 62 0.53 40.17 5.6 5.00
164 INT5490 Binding of CA2 52 0.36 9.73 5.53 5.00
165 INT147584 Localization of AIS 38 0.63 12.83 5.27 5.00
166 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 5.00
167 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22 5.00
168 INT10504 Localization of Pla2g1b 18 0.65 8.19 5.05 5.00
169 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 5.00
170 INT105336 Regulation of AKT1 52 0.56 32.53 4.89 5.00
171 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86 5.00
172 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 5.00
173 INT49805 Positive_regulation of MUC1 56 0.70 44.5 4.56 5.00
174 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45 5.00
175 INT109450 Positive_regulation of Phosphorylation of AKT1 62 0.64 25.18 4.21 5.00
176 INT138872 Gene_expression of SPINK5 21 0.58 30.11 4.12 5.00
177 INT115889 Binding of Fas 27 0.36 28.87 4.08 5.00
178 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91 5.00
179 INT64766 Gene_expression of TWIST1 41 0.76 37.89 3.4 5.00
180 INT95652 Gene_expression of Krt20 54 0.61 53.69 3.31 5.00
181 INT51607 Positive_regulation of DES 33 0.67 32.24 3.29 5.00
182 INT10353 Positive_regulation of PGR 34 0.70 21.84 3.28 5.00
183 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21 5.00
184 INT192676 Binding of PTEN 14 0.46 10.58 3.06 5.00
185 INT69727 Gene_expression of QPCT 18 0.65 5.45 3.05 5.00
186 INT89392 Negative_regulation of Positive_regulation of AKT1 23 0.50 15.69 3.02 5.00
187 INT200670 Gene_expression of AKT2 25 0.75 16.25 3 5.00
188 INT134795 Positive_regulation of Scrib 30 0.22 36.91 2.81 5.00
189 INT89397 Positive_regulation of PIK3CA 33 0.67 16.98 2.78 5.00
190 INT121493 Gene_expression of XRCC1 55 0.65 73.43 2.76 5.00
191 INT74293 Positive_regulation of BAK1 13 0.60 14.13 2.73 5.00
192 INT1922 Positive_regulation of CEACAM7 32 0.70 33.31 2.72 5.00
193 INT19177 Negative_regulation of GRHPR 19 0.53 12.65 2.71 5.00
194 INT145328 Negative_regulation of Scrib 25 0.16 26.79 2.66 5.00
195 INT86815 Gene_expression of Pla2g2a 18 0.55 5.72 2.59 5.00
196 INT23954 Negative_regulation of Mb 24 0.49 11.27 2.55 5.00
197 INT12485 Binding of DNAH8 17 0.48 4.24 2.54 5.00
198 INT1921 Gene_expression of CEACAM7 47 0.78 43.23 2.53 5.00
199 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5 5.00
200 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 5.00
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