D:Livedo Reticularis

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pChart

Disease Term
Synonyms None
Documents 120
Hot Single Events 16
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Livedo Reticularis. They are ordered first by their relevance to Livedo Reticularis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT90387 ROS1 Positive_regulation of NFKB1 4 0.32 2.35 0.87 5.00
2 INT182771 ROS1 Positive_regulation of NFKB1 Positive_regulation of CRP 1 0.00 3.83 0.28 5.00
3 INT182772 ROS1 Positive_regulation of NFKB1 Positive_regulation of IL1B 1 0.00 1.89 0.14 5.00
4 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 5.00
5 INT182773 ROS1 Positive_regulation of NFKB1 Positive_regulation of IL6 1 0.00 1.9 0.14 5.00
6 INT182780 NFKB1 Positive_regulation of IL1B 1 0.00 1.8 0.14 5.00
7 INT182782 NFKB1 Positive_regulation of IL6 1 0.00 1.8 0.14 5.00
8 INT336341 Binding of RTCA and ELOVL1 1 0.02 2.15 0.07 5.00
9 INT182775 Binding of PTH and ROS1 1 0.04 1.73 0.04 5.00
10 INT182784 IGF1 Positive_regulation of Gene_expression of INS 1 0.02 1.87 0 5.00
11 INT182804 Binding of ETV3 and T2DM 1 0.10 2.62 0 5.00
12 INT182778 IGF1 Positive_regulation of Gene_expression of ETV3 1 0.03 1.89 0 5.00
13 INT182774 Binding of ETV3 and SAE1 1 0.00 1.17 0 5.00
14 INT182783 INS Positive_regulation of Gene_expression of ETV3 1 0.01 1.89 0 5.00
15 INT182777 IAPP Positive_regulation of Gene_expression of ETV3 1 0.06 1.88 0 5.00
16 INT182776 IAPP Positive_regulation of Gene_expression of INS 1 0.03 1.87 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Livedo Reticularis. They are ordered first by their pain relevance and then by number of times they were reported in Livedo Reticularis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT128124 Gene_expression of Ccdc88a 1 0.11 0.71 0.08 99.76
2 INT77670 Positive_regulation of ACLY 24 0.49 21.68 3.12 96.76
3 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 96.48
4 INT20982 Positive_regulation of SERPINB1 7 0.28 7.27 1.61 96.36
5 INT92769 Positive_regulation of Arsk 1 0.05 2.16 0.13 95.56
6 INT182794 Gene_expression of CPLX1 1 0.06 5.57 0.17 95.52
7 INT9900 Positive_regulation of Vwf 80 0.69 51.85 18.13 94.52
8 INT10147 Gene_expression of Serpinc1 28 0.76 17.73 5.77 91.32
9 INT8866 Positive_regulation of TAT 30 0.67 18.06 5.57 88.56
10 INT11710 Positive_regulation of SERPINC1 6 0.59 6.15 1.47 88.56
11 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 87.44
12 INT27236 Negative_regulation of F13a1 17 0.53 10.79 1.99 84.36
13 INT1888 Protein_catabolism of F13A1 97 0.99 63.48 14.82 83.64
14 INT182792 Regulation of STS 4 0.47 2.91 0.61 82.44
15 INT81206 Binding of ENPEP 11 0.47 5.19 0.88 82.32
16 INT32203 Negative_regulation of Crp 48 0.58 32.77 11.89 81.20
17 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 79.76
18 INT35143 Negative_regulation of ANGPTL5 28 0.54 18.59 3.14 79.40
19 INT86670 Negative_regulation of AGXT 6 0.57 2.24 1.18 74.24
20 INT102187 Gene_expression of SH2B2 23 0.59 26.54 4.39 72.80
21 INT11867 Positive_regulation of Positive_regulation of TAT 2 0.49 2.02 0.54 72.28
22 INT59194 Gene_expression of STS 18 0.59 6.74 1.89 64.64
23 INT99289 Localization of STS 8 0.79 6.5 0.92 63.68
24 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 60.64
25 INT182788 Gene_expression of ETV3 8 0.40 11.33 0.36 60.64
26 INT143346 Localization of Mthfr 2 0.54 0.4 0.04 59.00
27 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 58.60
28 INT209501 Gene_expression of CADPS 15 0.65 20.7 2.22 49.20
29 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 34.00
30 INT82166 Regulation of NOS3 14 0.54 7.57 2.08 21.00
31 INT76091 Positive_regulation of NOS3 48 0.61 18.4 7.92 20.60
32 INT35584 Binding of ACLY 22 0.35 31.78 7.17 19.12
33 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48 17.44
34 INT62895 Gene_expression of NOSTRIN 51 0.75 28.8 10.68 17.44
35 INT175262 Binding of SH2B2 18 0.36 22.85 3.18 6.24
36 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
37 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
38 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
39 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
40 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32 5.00
41 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
42 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
43 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
44 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
45 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 5.00
46 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 5.00
47 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 5.00
48 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 5.00
49 INT100861 Binding of CRP 179 0.48 175.2 26.45 5.00
50 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 5.00
51 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 5.00
52 INT89484 Gene_expression of TNFRSF11B 119 0.76 53.57 19.67 5.00
53 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 5.00
54 INT78024 Gene_expression of ACLY 73 0.75 59.15 18.54 5.00
55 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 5.00
56 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42 5.00
57 INT48335 Negative_regulation of NOSTRIN 38 0.56 16.22 12.05 5.00
58 INT16772 Gene_expression of MPO 81 0.78 90.98 11.9 5.00
59 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 5.00
60 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35 5.00
61 INT94784 Binding of ROS1 113 0.40 71.57 10.26 5.00
62 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51 5.00
63 INT6512 Gene_expression of PTH 103 0.77 76.29 6.33 5.00
64 INT57720 Localization of IGHG3 33 0.74 20.24 6.25 5.00
65 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 5.00
66 INT45753 Localization of CD40LG 45 0.79 32.31 5.28 5.00
67 INT66423 Binding of ELOVL1 52 0.40 61.63 5.16 5.00
68 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32 5.00
69 INT47949 Positive_regulation of ELOVL1 19 0.42 29.78 3.3 5.00
70 INT61791 Positive_regulation of SH2B2 9 0.50 8.36 2.99 5.00
71 INT16130 Binding of IGF1 67 0.48 27.43 2.95 5.00
72 INT26996 Positive_regulation of Gene_expression of Crp 21 0.68 21.55 2.75 5.00
73 INT12618 Positive_regulation of IAPP 54 0.68 32.03 2.29 5.00
74 INT11183 Negative_regulation of SH2B2 4 0.34 6.99 2.12 5.00
75 INT56221 Regulation of MPO 8 0.61 8.44 1.84 5.00
76 INT51840 Positive_regulation of Localization of CD40LG 8 0.69 9.59 1.58 5.00
77 INT12035 Regulation of F2 21 0.45 12.66 1.47 5.00
78 INT259036 Transcription of SH2B2 2 0.55 7.01 1.46 5.00
79 INT18844 Binding of IAPP 11 0.36 11.01 1.45 5.00
80 INT47950 Negative_regulation of ELOVL1 15 0.41 20.33 1.41 5.00
81 INT181868 Localization of ACLY 5 0.62 6.36 1.4 5.00
82 INT6514 Positive_regulation of Gene_expression of PTH 28 0.67 30.28 1.37 5.00
83 INT236277 Positive_regulation of Gene_expression of CADPS 5 0.42 9.17 1.29 5.00
84 INT158540 Negative_regulation of HTN1 4 0.34 7.25 1.22 5.00
85 INT169363 Negative_regulation of PTGIS 4 0.20 3.35 1.22 5.00
86 INT209503 Positive_regulation of CADPS 3 0.42 7 1.11 5.00
87 INT158542 Gene_expression of HTN1 10 0.75 10.69 1.07 5.00
88 INT158541 Positive_regulation of Gene_expression of HTN1 3 0.40 5.88 0.97 5.00
89 INT158409 Gene_expression of T2DM 3 0.65 9.58 0.56 5.00
90 INT52740 Binding of ACLS 5 0.31 3 0.54 5.00
91 INT259035 Localization of SH2B2 3 0.43 1.77 0.42 5.00
92 INT182790 Positive_regulation of SAE1 3 0.49 3.18 0.39 5.00
93 INT182787 Binding of ETV3 14 0.37 25.44 0.37 5.00
94 INT259031 Negative_regulation of Gene_expression of CADPS 1 0.07 3.04 0.35 5.00
95 INT42244 Regulation of Gene_expression of PTH 5 0.45 3.95 0.34 5.00
96 INT131019 Binding of T2DM 6 0.47 6.97 0.31 5.00
97 INT182791 Binding of CPLX1 1 0.04 2.85 0.3 5.00
98 INT182752 Negative_regulation of T2DM 1 0.41 2.06 0.29 5.00
99 INT121834 Gene_expression of IAPP 24 0.66 20.96 0.26 5.00
100 INT17009 Regulation of CADPS 2 0.08 1.97 0.24 5.00
101 INT6604 Binding of ITGA3 3 0.14 3.37 0.22 5.00
102 INT175260 Negative_regulation of Gene_expression of SH2B2 2 0.25 4.41 0.21 5.00
103 INT129762 Binding of HTN1 5 0.03 5.68 0.19 5.00
104 INT157725 Gene_expression of ACLS 2 0.13 2.89 0.17 5.00
105 INT259033 Gene_expression of LCA5L 1 0.01 2.71 0.16 5.00
106 INT259032 Binding of PEX1 2 0.01 4.67 0.15 5.00
107 INT182800 Positive_regulation of ETV3 5 0.46 10.01 0.14 5.00
108 INT259037 Negative_regulation of Binding of ACLY 1 0.07 1.54 0.13 5.00
109 INT259038 Negative_regulation of Positive_regulation of SH2B2 1 0.25 1.83 0.09 5.00
110 INT259039 Positive_regulation of Binding of ACLY 1 0.09 1.85 0.09 5.00
111 INT259030 Negative_regulation of Gene_expression of ACLY 1 0.07 1.95 0.08 5.00
112 INT182785 Gene_expression of NHEJ1 1 0.01 1.08 0.06 5.00
113 INT193358 Localization of ST3GAL4 2 0.52 1.65 0.05 5.00
114 INT259040 Phosphorylation of SH2B2 1 0.47 0.85 0.03 5.00
115 INT259029 Regulation of Phosphorylation of SH2B2 1 0.26 0.85 0.03 5.00
116 INT182754 Positive_regulation of T2DM 1 0.67 4.5 0.03 5.00
117 INT182799 Positive_regulation of Gene_expression of CPLX1 1 0.04 1.49 0.03 5.00
118 INT182801 Positive_regulation of CPLX1 1 0.04 2.92 0.03 5.00
119 INT182753 Positive_regulation of Binding of 1 0.49 1.88 0 5.00
120 INT182786 Positive_regulation of Binding of ETV3 1 0.12 1.88 0 5.00
121 INT259024 Regulation of Anxa5 1 0.44 1.25 0 5.00
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