D:Liver Cell Adenoma

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Disease Term
Synonyms Adenoma Hepatocellular, ADENOMAS HEPATOCELLULAR, Adenomas Liver Cell, BENIGN HEPATOMA, BENIGN HEPATOMAS, Hepatocellular Adenoma, Hepatocellular Adenomas, Hepatoma Benign, HEPATOMAS BENIGN, Liver Cell Adenomas
Documents 57
Hot Single Events 16
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Liver Cell Adenoma. They are ordered first by their relevance to Liver Cell Adenoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT327112 HCCS Positive_regulation of Gene_expression of SLCO1B3 1 0.03 0.65 0.19 5.00
2 INT232018 Binding of SERPING1 and KNG1 1 0.15 0.81 0.14 5.00
3 INT232015 SERPING1 Negative_regulation of F12 2 0.24 1.19 0.12 5.00
4 INT232017 F12 Positive_regulation of PLG 1 0.03 0.52 0.11 5.00
5 INT232019 F12 Positive_regulation of TRGC1 1 0.00 0.57 0.09 5.00
6 INT232010 PLG Positive_regulation of TRGC1 1 0.08 0.51 0.09 5.00
7 INT232011 SERPING1 Regulation of Negative_regulation of SERPINE1 1 0.01 0.45 0.07 5.00
8 INT232009 Positive_regulation of F12 Negative_regulation of Localization of KNG1 1 0.01 0.19 0.05 5.00
9 INT327162 Binding of SERPING1 and F12 1 0.05 0.29 0.04 5.00
10 INT232013 SERPING1 Negative_regulation of C1S 1 0.24 0.72 0.04 5.00
11 INT232012 SERPING1 Negative_regulation of C1R 1 0.18 0.72 0.04 5.00
12 INT353192 Stat5a Positive_regulation of Plxna3 1 0.01 0 0 5.00
13 INT232016 SERPING1 Regulation of C1S 1 0.15 0.57 0 5.00
14 INT353189 Plxna3 Negative_regulation of Cyp4a8 1 0.01 0.35 0 5.00
15 INT260375 Binding of T2 and Htas2 1 0.00 0.18 0 5.00
16 INT353197 ARNTL Regulation of Hlf 1 0.29 0.33 0 5.00
17 INT353188 Ggh Regulation of Cux2 1 0.11 0.08 0 5.00
18 INT353191 Renbp Regulation of Gene_expression of Yif1 1 0.00 0.55 0 5.00
19 INT260382 Das Negative_regulation of Gene_expression of IGLL1 1 0.00 0.94 0 5.00
20 INT353195 ARNTL Regulation of Gene_expression of Tef 1 0.22 0.33 0 5.00
21 INT353199 Cux2 Regulation of Plxna3 Negative_regulation of Cyp4a8 1 0.01 0.35 0 5.00
22 INT353187 Ggh Regulation of Hoxa2 1 0.01 0.08 0 5.00
23 INT353196 ARNTL Regulation of Tef 1 0.36 0.32 0 5.00
24 INT353190 Stat5a Positive_regulation of Cyp2c11 1 0.31 0 0 5.00
25 INT261981 EP400 Negative_regulation of CYP1B1 1 0.01 0.22 0 5.00
26 INT353198 ARNTL Regulation of Dbp 1 0.32 0.32 0 5.00
27 INT353194 ARNTL Regulation of Localization of Ahr 1 0.27 0.32 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Liver Cell Adenoma. They are ordered first by their pain relevance and then by number of times they were reported in Liver Cell Adenoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT50568 Positive_regulation of HCA1 5 0.44 5.56 1.63 100.00
2 INT159806 Binding of HCA1 4 0.32 1.57 0.24 100.00
3 INT31407 Negative_regulation of HCA1 4 0.38 3.07 1.34 100.00
4 INT50569 Gene_expression of HCA1 10 0.59 3.76 0.89 100.00
5 INT31408 Localization of HCA1 4 0.28 1.4 0.33 100.00
6 INT60685 Positive_regulation of Gene_expression of Epo 21 0.53 15.86 1.25 99.08
7 INT139321 Positive_regulation of Saa2 5 0.48 6.64 0.54 98.94
8 INT147607 Binding of TERT 16 0.48 12.36 1.31 98.92
9 INT2843 Gene_expression of Epo 100 0.78 62.01 14.66 98.56
10 INT89370 Gene_expression of Clta 4 0.51 4.22 0.22 93.04
11 INT197143 Positive_regulation of Renbp 15 0.33 9.41 1.31 91.16
12 INT156130 Binding of SERPING1 29 0.42 26.16 2.52 87.68
13 INT608 Negative_regulation of KNG1 98 0.43 72.36 31.23 86.16
14 INT93877 Binding of Clta 2 0.18 1.29 0.23 84.04
15 INT64888 Negative_regulation of HBM 52 0.16 34.33 5.45 82.28
16 INT45717 Gene_expression of Yif1 3 0.52 3.22 0.27 81.68
17 INT7083 Positive_regulation of HBM 35 0.66 20.96 4.3 78.12
18 INT11488 Negative_regulation of KLK1 15 0.57 9.92 3.06 75.32
19 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 74.08
20 INT22132 Positive_regulation of CAT 41 0.67 18.64 10.67 72.68
21 INT14470 Gene_expression of HCC 83 0.67 110.55 4.61 62.64
22 INT205618 Gene_expression of Renbp 15 0.26 9.26 1.04 61.68
23 INT316316 Negative_regulation of Binding of F12 1 0.18 1.1 0.12 59.56
24 INT77164 Binding of F12 8 0.47 2.66 1.48 59.08
25 INT10138 Negative_regulation of Gene_expression of KNG1 13 0.57 9.57 4.9 56.16
26 INT316317 Negative_regulation of Gene_expression of KLK1 1 0.41 1.04 0.12 56.16
27 INT26451 Gene_expression of KLK1 14 0.75 5.79 1.66 55.60
28 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 55.16
29 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66 55.00
30 INT80657 Gene_expression of SLC17A5 50 0.75 39.98 5.44 54.96
31 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 51.24
32 INT6510 Gene_expression of AFP 130 0.78 119.2 9.19 42.60
33 INT58883 Gene_expression of T2 12 0.63 2.56 0.71 38.24
34 INT260381 Gene_expression of TFPT 1 0.16 0.84 0.05 38.24
35 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 36.60
36 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 32.64
37 INT353181 Gene_expression of Ids 1 0.26 0.61 0 31.04
38 INT352264 Gene_expression of Degs1 2 0.46 0.6 0 30.16
39 INT3845 Gene_expression of GSR 79 0.76 44.69 11.19 29.92
40 INT316318 Phosphorylation of SERPING1 2 0.81 1.7 0.13 27.12
41 INT119605 Positive_regulation of Anxa5 2 0.67 2.3 0.16 25.00
42 INT144481 Gene_expression of SERPING1 55 0.77 50.4 4.75 17.64
43 INT597 Positive_regulation of PON1 26 0.62 19.14 2.87 17.44
44 INT58571 Positive_regulation of ALDOB 6 0.49 5.63 0.53 17.44
45 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
46 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
47 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
48 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
49 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 5.00
50 INT1047 Negative_regulation of LH 314 0.59 53.71 135.89 5.00
51 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 5.00
52 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
53 INT7134 Localization of KNG1 127 0.79 65.73 67.97 5.00
54 INT1046 Gene_expression of LH 180 0.77 29.75 66.87 5.00
55 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
56 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74 5.00
57 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
58 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 5.00
59 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 5.00
60 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
61 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
62 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51 5.00
63 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72 5.00
64 INT3076 Regulation of KNG1 52 0.60 20.39 27.89 5.00
65 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 5.00
66 INT3167 Binding of KNG1 48 0.48 23.26 26.77 5.00
67 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 5.00
68 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 5.00
69 INT20305 Gene_expression of Cyp2e1 53 0.78 19.75 19.54 5.00
70 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 5.00
71 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 5.00
72 INT3364 Binding of SGCG 87 0.47 31.93 17.24 5.00
73 INT76406 Gene_expression of Hmox1 140 0.78 85.86 17.15 5.00
74 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 5.00
75 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51 5.00
76 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 5.00
77 INT1000 Localization of Ggh 31 0.75 2.74 16.41 5.00
78 INT61117 Gene_expression of Ppara 158 0.68 69.3 15.98 5.00
79 INT7970 Gene_expression of PLOD1 120 0.71 44.42 15.54 5.00
80 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 5.00
81 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 5.00
82 INT180497 Binding of MRI1 45 0.42 28.35 14.77 5.00
83 INT2758 Binding of Dbp 36 0.44 8.3 14.47 5.00
84 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 5.00
85 INT53747 Positive_regulation of Cyp2e1 34 0.70 29.03 13.39 5.00
86 INT4145 Gene_expression of FSHR 124 0.77 44.98 13.04 5.00
87 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54 5.00
88 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 5.00
89 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 5.00
90 INT9832 Gene_expression of Shbg 96 0.75 56.71 12.19 5.00
91 INT48335 Negative_regulation of NOSTRIN 38 0.56 16.22 12.05 5.00
92 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 5.00
93 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 5.00
94 INT2378 Negative_regulation of SERPINE1 47 0.59 34.55 9.9 5.00
95 INT91370 Phosphorylation of STAT3 123 0.82 49.25 8.42 5.00
96 INT121496 Gene_expression of TERT 107 0.78 45.6 7.42 5.00
97 INT16618 Negative_regulation of SERPING1 81 0.59 86.28 7.17 5.00
98 INT17674 Localization of Scn2a1 32 0.61 1.73 6.79 5.00
99 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61 5.00
100 INT17913 Regulation of HSD11B1 87 0.60 93.23 6.04 5.00
101 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93 5.00
102 INT21103 Gene_expression of Dbp 48 0.61 22.6 5.59 5.00
103 INT11480 Positive_regulation of Localization of KNG1 15 0.30 6.39 5.5 5.00
104 INT118124 Binding of USE1 24 0.16 16.64 5.44 5.00
105 INT23952 Gene_expression of Cyp2d4 18 0.78 4.76 5.31 5.00
106 INT60585 Regulation of TP53 59 0.59 54.55 5.21 5.00
107 INT201130 Localization of AES 31 0.63 25.45 5.12 5.00
108 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07 5.00
109 INT11493 Positive_regulation of KLK1 21 0.67 9.22 5 5.00
110 INT12104 Positive_regulation of PLG 45 0.68 28.94 4.81 5.00
111 INT8340 Negative_regulation of SHBG 49 0.57 35.96 4.73 5.00
112 INT84686 Regulation of BAX 26 0.49 28.54 4.13 5.00
113 INT32705 Gene_expression of Cyp2c12 7 0.65 0.62 4.11 5.00
114 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07 5.00
115 INT72936 Gene_expression of Pparg 39 0.77 19.01 4.02 5.00
116 INT101857 Negative_regulation of BCL2L1 22 0.57 23.56 3.95 5.00
117 INT76149 Gene_expression of Das 18 0.37 6.55 3.92 5.00
118 INT20303 Regulation of Cyp2e1 11 0.61 2.46 3.84 5.00
119 INT34720 Positive_regulation of SHBG 58 0.69 32.4 3.83 5.00
120 INT16165 Regulation of DMD 114 0.60 35.13 3.64 5.00
121 INT97126 Regulation of CASP3 9 0.40 8.15 3.6 5.00
122 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32 5.00
123 INT10136 Negative_regulation of PLAT 23 0.42 11.18 3.02 5.00
124 INT9335 Gene_expression of Igf2 18 0.72 12.76 2.78 5.00
125 INT90875 Negative_regulation of CCND1 31 0.42 26.22 2.66 5.00
126 INT72782 Positive_regulation of HCC 41 0.40 63.74 2.46 5.00
127 INT22679 Binding of SERPINE1 25 0.36 17.33 2.36 5.00
128 INT70242 Localization of HCC 18 0.66 23.95 2.35 5.00
129 INT50558 Negative_regulation of PCNA 31 0.57 13.97 2.3 5.00
130 INT94002 Regulation of Lox 13 0.38 8.41 2.29 5.00
131 INT70962 Positive_regulation of SERPING1 33 0.69 27.32 2.14 5.00
132 INT78429 Positive_regulation of TRGC1 11 0.44 4.6 2.1 5.00
133 INT40647 Gene_expression of Ggh 5 0.59 0.24 2.03 5.00
134 INT35146 Negative_regulation of PLG 27 0.57 17.63 1.98 5.00
135 INT88375 Negative_regulation of Localization of KNG1 4 0.39 1.12 1.91 5.00
136 INT21487 Negative_regulation of HCC 18 0.49 29.81 1.88 5.00
137 INT79140 Binding of HCC 36 0.31 46.96 1.87 5.00
138 INT85084 Gene_expression of KRT19 66 0.73 42.56 1.82 5.00
139 INT11481 Positive_regulation of F12 11 0.58 5.53 1.8 5.00
140 INT31815 Gene_expression of Arntl 4 0.75 1.51 1.8 5.00
141 INT45041 Gene_expression of IGLL1 18 0.66 15.45 1.59 5.00
142 INT574 Negative_regulation of C1S 9 0.47 11.25 1.41 5.00
143 INT201463 Negative_regulation of CCNE2 7 0.39 3.31 1.36 5.00
144 INT3816 Gene_expression of Ahr 13 0.65 7.51 1.31 5.00
145 INT14205 Regulation of KLK1 10 0.60 4.38 1.28 5.00
146 INT11496 Negative_regulation of F12 6 0.59 3.41 1.27 5.00
147 INT156672 Localization of SERPING1 10 0.74 12.15 1.25 5.00
148 INT49013 Gene_expression of Por 6 0.75 2.19 1.22 5.00
149 INT53285 Gene_expression of Cyp2c11 20 0.76 5.43 1.17 5.00
150 INT175652 Positive_regulation of BPHL 9 0.44 17.98 1.14 5.00
151 INT103043 Binding of PDE5A 16 0.37 7.79 1.12 5.00
152 INT96873 Gene_expression of CYP1B1 28 0.78 11.81 1.09 5.00
153 INT34586 Positive_regulation of Negative_regulation of HSD11B1 6 0.49 4.39 1.05 5.00
154 INT128609 Gene_expression of C1S 18 0.75 17.36 0.98 5.00
155 INT144482 Negative_regulation of Gene_expression of SERPING1 8 0.43 6.06 0.89 5.00
156 INT35141 Regulation of PLG 6 0.44 2.64 0.85 5.00
157 INT141591 Negative_regulation of Positive_regulation of GPT 2 0.42 0.83 0.8 5.00
158 INT96879 Positive_regulation of CYP1B1 14 0.70 5.73 0.78 5.00
159 INT327119 Gene_expression of HCCS 1 0.12 2.47 0.74 5.00
160 INT2395 Binding of MB 18 0.36 7.53 0.68 5.00
161 INT208371 Localization of Ahr 2 0.50 1.9 0.66 5.00
162 INT219793 Negative_regulation of Renbp 5 0.13 3.42 0.61 5.00
163 INT174106 Binding of Renbp 18 0.24 15.82 0.58 5.00
164 INT248682 Gene_expression of Rxrb 8 0.60 1.41 0.58 5.00
165 INT145530 Negative_regulation of Positive_regulation of KLK1 2 0.42 1.02 0.57 5.00
166 INT205619 Regulation of Renbp 6 0.17 1.91 0.55 5.00
167 INT327116 Positive_regulation of Localization of AES 4 0.22 2.69 0.55 5.00
168 INT173801 Gene_expression of Ik 11 0.36 1.31 0.51 5.00
169 INT221932 Gene_expression of F12 4 0.66 2.61 0.5 5.00
170 INT327120 Positive_regulation of Positive_regulation of MRI1 1 0.05 0 0.5 5.00
171 INT175759 Gene_expression of ARNTL 9 0.75 0.8 0.44 5.00
172 INT55807 Negative_regulation of GPT 4 0.42 4.11 0.44 5.00
173 INT88678 Gene_expression of CYP27B1 8 0.75 2.11 0.41 5.00
174 INT197012 Regulation of Gene_expression of LDLR 4 0.40 1.31 0.4 5.00
175 INT327121 Positive_regulation of Gene_expression of HCCS 1 0.07 1.3 0.37 5.00
176 INT316315 Negative_regulation of Binding of SERPING1 2 0.37 1.4 0.34 5.00
177 INT184641 Regulation of TRGC1 4 0.40 2.84 0.34 5.00
178 INT45040 Positive_regulation of Gene_expression of IGLL1 4 0.59 1.59 0.33 5.00
179 INT81196 Regulation of T2 3 0.11 1.92 0.33 5.00
180 INT120525 Gene_expression of SLCO1B3 2 0.57 1.47 0.33 5.00
181 INT274379 Negative_regulation of Binding of SERPINE1 1 0.03 0.91 0.33 5.00
182 INT118610 Localization of BPHL 6 0.57 6.88 0.33 5.00
183 INT302888 Positive_regulation of HIST1H4PS1 3 0.05 1.52 0.32 5.00
184 INT174112 Positive_regulation of Gene_expression of KRT19 4 0.44 4.28 0.31 5.00
185 INT232021 Positive_regulation of Gene_expression of SERPING1 8 0.49 4.99 0.31 5.00
186 INT158730 Gene_expression of Plxna3 4 0.65 1.82 0.29 5.00
187 INT75006 Gene_expression of Gstm1 6 0.45 2.19 0.29 5.00
188 INT174519 Gene_expression of C1R 4 0.35 0.51 0.29 5.00
189 INT26453 Binding of KLK1 2 0.47 0.84 0.28 5.00
190 INT232024 Protein_catabolism of KLK1 2 0.64 1.21 0.28 5.00
191 INT257785 Positive_regulation of KIN 3 0.45 0.72 0.24 5.00
192 INT113989 Regulation of Gene_expression of CCND1 11 0.44 7.57 0.24 5.00
193 INT96885 Localization of CYP1B1 4 0.80 2.11 0.23 5.00
194 INT41984 Regulation of Gene_expression of HSD11B1 4 0.44 4.18 0.23 5.00
195 INT96888 Negative_regulation of Gene_expression of CYP1B1 5 0.43 1.13 0.23 5.00
196 INT96883 Positive_regulation of Gene_expression of CYP1B1 3 0.70 1.24 0.22 5.00
197 INT28719 Binding of T2 3 0.20 1.55 0.21 5.00
198 INT81197 Transcription of T2 2 0.17 1.37 0.21 5.00
199 INT228644 Positive_regulation of Negative_regulation of SERPING1 5 0.46 4.21 0.21 5.00
200 INT260372 Transcription of Das 2 0.09 1.6 0.19 5.00
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