D:Liver Cell Adenoma

Disease Term Synonyms Adenoma Hepatocellular, ADENOMAS HEPATOCELLULAR, Adenomas Liver Cell, BENIGN HEPATOMA, BENIGN HEPATOMAS, Hepatocellular Adenoma, Hepatocellular Adenomas, Hepatoma Benign, HEPATOMAS BENIGN, Liver Cell Adenomas Documents 57 Hot Single Events 16 Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Liver Cell Adenoma. They are ordered first by their relevance to Liver Cell Adenoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT327112	HCCS Positive_regulation of Gene_expression of SLCO1B3	1	0.03	0.65	0.19	5.00
2	INT232018	Binding of SERPING1 and KNG1	1	0.15	0.81	0.14	5.00
3	INT232015	SERPING1 Negative_regulation of F12	2	0.24	1.19	0.12	5.00
4	INT232017	F12 Positive_regulation of PLG	1	0.03	0.52	0.11	5.00
5	INT232019	F12 Positive_regulation of TRGC1	1	0.00	0.57	0.09	5.00
6	INT232010	PLG Positive_regulation of TRGC1	1	0.08	0.51	0.09	5.00
7	INT232011	SERPING1 Regulation of Negative_regulation of SERPINE1	1	0.01	0.45	0.07	5.00
8	INT232009	Positive_regulation of F12 Negative_regulation of Localization of KNG1	1	0.01	0.19	0.05	5.00
9	INT327162	Binding of SERPING1 and F12	1	0.05	0.29	0.04	5.00
10	INT232013	SERPING1 Negative_regulation of C1S	1	0.24	0.72	0.04	5.00
11	INT232012	SERPING1 Negative_regulation of C1R	1	0.18	0.72	0.04	5.00
12	INT353192	Stat5a Positive_regulation of Plxna3	1	0.01	0	0	5.00
13	INT232016	SERPING1 Regulation of C1S	1	0.15	0.57	0	5.00
14	INT353189	Plxna3 Negative_regulation of Cyp4a8	1	0.01	0.35	0	5.00
15	INT260375	Binding of T2 and Htas2	1	0.00	0.18	0	5.00
16	INT353197	ARNTL Regulation of Hlf	1	0.29	0.33	0	5.00
17	INT353188	Ggh Regulation of Cux2	1	0.11	0.08	0	5.00
18	INT353191	Renbp Regulation of Gene_expression of Yif1	1	0.00	0.55	0	5.00
19	INT260382	Das Negative_regulation of Gene_expression of IGLL1	1	0.00	0.94	0	5.00
20	INT353195	ARNTL Regulation of Gene_expression of Tef	1	0.22	0.33	0	5.00
21	INT353199	Cux2 Regulation of Plxna3 Negative_regulation of Cyp4a8	1	0.01	0.35	0	5.00
22	INT353187	Ggh Regulation of Hoxa2	1	0.01	0.08	0	5.00
23	INT353196	ARNTL Regulation of Tef	1	0.36	0.32	0	5.00
24	INT353190	Stat5a Positive_regulation of Cyp2c11	1	0.31	0	0	5.00
25	INT261981	EP400 Negative_regulation of CYP1B1	1	0.01	0.22	0	5.00
26	INT353198	ARNTL Regulation of Dbp	1	0.32	0.32	0	5.00
27	INT353194	ARNTL Regulation of Localization of Ahr	1	0.27	0.32	0	5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Liver Cell Adenoma. They are ordered first by their pain relevance and then by number of times they were reported in Liver Cell Adenoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT50568	Positive_regulation of HCA1	5	0.44	5.56	1.63	100.00
2	INT159806	Binding of HCA1	4	0.32	1.57	0.24	100.00
3	INT31407	Negative_regulation of HCA1	4	0.38	3.07	1.34	100.00
4	INT50569	Gene_expression of HCA1	10	0.59	3.76	0.89	100.00
5	INT31408	Localization of HCA1	4	0.28	1.4	0.33	100.00
6	INT60685	Positive_regulation of Gene_expression of Epo	21	0.53	15.86	1.25	99.08
7	INT139321	Positive_regulation of Saa2	5	0.48	6.64	0.54	98.94
8	INT147607	Binding of TERT	16	0.48	12.36	1.31	98.92
9	INT2843	Gene_expression of Epo	100	0.78	62.01	14.66	98.56
10	INT89370	Gene_expression of Clta	4	0.51	4.22	0.22	93.04
11	INT197143	Positive_regulation of Renbp	15	0.33	9.41	1.31	91.16
12	INT156130	Binding of SERPING1	29	0.42	26.16	2.52	87.68
13	INT608	Negative_regulation of KNG1	98	0.43	72.36	31.23	86.16
14	INT93877	Binding of Clta	2	0.18	1.29	0.23	84.04
15	INT64888	Negative_regulation of HBM	52	0.16	34.33	5.45	82.28
16	INT45717	Gene_expression of Yif1	3	0.52	3.22	0.27	81.68
17	INT7083	Positive_regulation of HBM	35	0.66	20.96	4.3	78.12
18	INT11488	Negative_regulation of KLK1	15	0.57	9.92	3.06	75.32
19	INT4420	Positive_regulation of GOT1	103	0.64	88.4	18.38	74.08
20	INT22132	Positive_regulation of CAT	41	0.67	18.64	10.67	72.68
21	INT14470	Gene_expression of HCC	83	0.67	110.55	4.61	62.64
22	INT205618	Gene_expression of Renbp	15	0.26	9.26	1.04	61.68
23	INT316316	Negative_regulation of Binding of F12	1	0.18	1.1	0.12	59.56
24	INT77164	Binding of F12	8	0.47	2.66	1.48	59.08
25	INT10138	Negative_regulation of Gene_expression of KNG1	13	0.57	9.57	4.9	56.16
26	INT316317	Negative_regulation of Gene_expression of KLK1	1	0.41	1.04	0.12	56.16
27	INT26451	Gene_expression of KLK1	14	0.75	5.79	1.66	55.60
28	INT17564	Gene_expression of Gpt	322	0.75	208.51	60.36	55.16
29	INT8357	Gene_expression of KNG1	153	0.75	77.26	68.66	55.00
30	INT80657	Gene_expression of SLC17A5	50	0.75	39.98	5.44	54.96
31	INT58192	Positive_regulation of MRI1	86	0.61	53.81	24.68	51.24
32	INT6510	Gene_expression of AFP	130	0.78	119.2	9.19	42.60
33	INT58883	Gene_expression of T2	12	0.63	2.56	0.71	38.24
34	INT260381	Gene_expression of TFPT	1	0.16	0.84	0.05	38.24
35	INT2129	Positive_regulation of F2	83	0.70	58.95	12.63	36.60
36	INT8683	Positive_regulation of F3	31	0.67	42.89	6.21	32.64
37	INT353181	Gene_expression of Ids	1	0.26	0.61	0	31.04
38	INT352264	Gene_expression of Degs1	2	0.46	0.6	0	30.16
39	INT3845	Gene_expression of GSR	79	0.76	44.69	11.19	29.92
40	INT316318	Phosphorylation of SERPING1	2	0.81	1.7	0.13	27.12
41	INT119605	Positive_regulation of Anxa5	2	0.67	2.3	0.16	25.00
42	INT144481	Gene_expression of SERPING1	55	0.77	50.4	4.75	17.64
43	INT597	Positive_regulation of PON1	26	0.62	19.14	2.87	17.44
44	INT58571	Positive_regulation of ALDOB	6	0.49	5.63	0.53	17.44
45	INT6483	Gene_expression of TNF	3152	0.78	2515.62	929.82	5.00
46	INT9238	Gene_expression of IL6	1575	0.78	1135.66	424.22	5.00
47	INT5059	Positive_regulation of TNF	1050	0.70	896.51	322.81	5.00
48	INT5972	Gene_expression of IL1B	948	0.78	510.91	263.97	5.00
49	INT767	Localization of Gnrhr	565	0.80	106.68	214.57	5.00
50	INT1047	Negative_regulation of LH	314	0.59	53.71	135.89	5.00
51	INT62124	Gene_expression of NOS1	444	0.78	218.08	114.85	5.00
52	INT3038	Gene_expression of INS	1583	0.78	1174.16	107.01	5.00
53	INT7134	Localization of KNG1	127	0.79	65.73	67.97	5.00
54	INT1046	Gene_expression of LH	180	0.77	29.75	66.87	5.00
55	INT17401	Gene_expression of IGF1	475	0.78	232.18	62.07	5.00
56	INT11491	Positive_regulation of KNG1	128	0.67	60.41	58.74	5.00
57	INT1199	Positive_regulation of INS	579	0.70	399.64	50.43	5.00
58	INT17881	Gene_expression of LEP	278	0.78	221.61	48.31	5.00
59	INT11560	Positive_regulation of CASP3	236	0.70	184.33	39.38	5.00
60	INT3758	Gene_expression of ALB	326	0.78	184.65	38.75	5.00
61	INT53475	Gene_expression of MRI1	116	0.59	77.68	33.98	5.00
62	INT8915	Gene_expression of Igf1	199	0.78	78.58	32.51	5.00
63	INT64113	Positive_regulation of Gene_expression of NOS1	110	0.60	71.03	29.72	5.00
64	INT3076	Regulation of KNG1	52	0.60	20.39	27.89	5.00
65	INT5206	Gene_expression of AR	316	0.78	113.83	27.29	5.00
66	INT3167	Binding of KNG1	48	0.48	23.26	26.77	5.00
67	INT9682	Positive_regulation of IGF1	238	0.70	120.03	26.36	5.00
68	INT2614	Gene_expression of CGA	187	0.78	105.89	24.77	5.00
69	INT20305	Gene_expression of Cyp2e1	53	0.78	19.75	19.54	5.00
70	INT28951	Negative_regulation of IGF1	133	0.59	75.77	18.9	5.00
71	INT56749	Gene_expression of PCNA	219	0.77	111.25	18.42	5.00
72	INT3364	Binding of SGCG	87	0.47	31.93	17.24	5.00
73	INT76406	Gene_expression of Hmox1	140	0.78	85.86	17.15	5.00
74	INT65856	Positive_regulation of TP53	138	0.67	112.65	16.71	5.00
75	INT19929	Negative_regulation of Positive_regulation of TNF	52	0.59	38.16	16.51	5.00
76	INT28950	Positive_regulation of Gene_expression of IGF1	99	0.69	46.9	16.47	5.00
77	INT1000	Localization of Ggh	31	0.75	2.74	16.41	5.00
78	INT61117	Gene_expression of Ppara	158	0.68	69.3	15.98	5.00
79	INT7970	Gene_expression of PLOD1	120	0.71	44.42	15.54	5.00
80	INT16166	Positive_regulation of DMD	348	0.67	133.22	15.06	5.00
81	INT505	Positive_regulation of GPT	89	0.67	69.38	14.94	5.00
82	INT180497	Binding of MRI1	45	0.42	28.35	14.77	5.00
83	INT2758	Binding of Dbp	36	0.44	8.3	14.47	5.00
84	INT18012	Gene_expression of EPO	169	0.78	108.36	13.75	5.00
85	INT53747	Positive_regulation of Cyp2e1	34	0.70	29.03	13.39	5.00
86	INT4145	Gene_expression of FSHR	124	0.77	44.98	13.04	5.00
87	INT89395	Negative_regulation of AKT1	127	0.58	70.27	12.54	5.00
88	INT24876	Gene_expression of CD34	172	0.78	91.02	12.39	5.00
89	INT28952	Negative_regulation of Gene_expression of IGF1	75	0.58	41.11	12.32	5.00
90	INT9832	Gene_expression of Shbg	96	0.75	56.71	12.19	5.00
91	INT48335	Negative_regulation of NOSTRIN	38	0.56	16.22	12.05	5.00
92	INT1735	Gene_expression of HSD11B1	199	0.75	257.87	11.5	5.00
93	INT1734	Negative_regulation of HSD11B1	116	0.57	125.13	10.52	5.00
94	INT2378	Negative_regulation of SERPINE1	47	0.59	34.55	9.9	5.00
95	INT91370	Phosphorylation of STAT3	123	0.82	49.25	8.42	5.00
96	INT121496	Gene_expression of TERT	107	0.78	45.6	7.42	5.00
97	INT16618	Negative_regulation of SERPING1	81	0.59	86.28	7.17	5.00
98	INT17674	Localization of Scn2a1	32	0.61	1.73	6.79	5.00
99	INT50387	Negative_regulation of AR	67	0.45	26.31	6.61	5.00
100	INT17913	Regulation of HSD11B1	87	0.60	93.23	6.04	5.00
101	INT75501	Gene_expression of CCND1	90	0.76	60.86	5.93	5.00
102	INT21103	Gene_expression of Dbp	48	0.61	22.6	5.59	5.00
103	INT11480	Positive_regulation of Localization of KNG1	15	0.30	6.39	5.5	5.00
104	INT118124	Binding of USE1	24	0.16	16.64	5.44	5.00
105	INT23952	Gene_expression of Cyp2d4	18	0.78	4.76	5.31	5.00
106	INT60585	Regulation of TP53	59	0.59	54.55	5.21	5.00
107	INT201130	Localization of AES	31	0.63	25.45	5.12	5.00
108	INT73262	Negative_regulation of BCL2	67	0.57	61.01	5.07	5.00
109	INT11493	Positive_regulation of KLK1	21	0.67	9.22	5	5.00
110	INT12104	Positive_regulation of PLG	45	0.68	28.94	4.81	5.00
111	INT8340	Negative_regulation of SHBG	49	0.57	35.96	4.73	5.00
112	INT84686	Regulation of BAX	26	0.49	28.54	4.13	5.00
113	INT32705	Gene_expression of Cyp2c12	7	0.65	0.62	4.11	5.00
114	INT111477	Gene_expression of KRT7	90	0.74	86.76	4.07	5.00
115	INT72936	Gene_expression of Pparg	39	0.77	19.01	4.02	5.00
116	INT101857	Negative_regulation of BCL2L1	22	0.57	23.56	3.95	5.00
117	INT76149	Gene_expression of Das	18	0.37	6.55	3.92	5.00
118	INT20303	Regulation of Cyp2e1	11	0.61	2.46	3.84	5.00
119	INT34720	Positive_regulation of SHBG	58	0.69	32.4	3.83	5.00
120	INT16165	Regulation of DMD	114	0.60	35.13	3.64	5.00
121	INT97126	Regulation of CASP3	9	0.40	8.15	3.6	5.00
122	INT87517	Gene_expression of LDLR	73	0.69	37.35	3.32	5.00
123	INT10136	Negative_regulation of PLAT	23	0.42	11.18	3.02	5.00
124	INT9335	Gene_expression of Igf2	18	0.72	12.76	2.78	5.00
125	INT90875	Negative_regulation of CCND1	31	0.42	26.22	2.66	5.00
126	INT72782	Positive_regulation of HCC	41	0.40	63.74	2.46	5.00
127	INT22679	Binding of SERPINE1	25	0.36	17.33	2.36	5.00
128	INT70242	Localization of HCC	18	0.66	23.95	2.35	5.00
129	INT50558	Negative_regulation of PCNA	31	0.57	13.97	2.3	5.00
130	INT94002	Regulation of Lox	13	0.38	8.41	2.29	5.00
131	INT70962	Positive_regulation of SERPING1	33	0.69	27.32	2.14	5.00
132	INT78429	Positive_regulation of TRGC1	11	0.44	4.6	2.1	5.00
133	INT40647	Gene_expression of Ggh	5	0.59	0.24	2.03	5.00
134	INT35146	Negative_regulation of PLG	27	0.57	17.63	1.98	5.00
135	INT88375	Negative_regulation of Localization of KNG1	4	0.39	1.12	1.91	5.00
136	INT21487	Negative_regulation of HCC	18	0.49	29.81	1.88	5.00
137	INT79140	Binding of HCC	36	0.31	46.96	1.87	5.00
138	INT85084	Gene_expression of KRT19	66	0.73	42.56	1.82	5.00
139	INT11481	Positive_regulation of F12	11	0.58	5.53	1.8	5.00
140	INT31815	Gene_expression of Arntl	4	0.75	1.51	1.8	5.00
141	INT45041	Gene_expression of IGLL1	18	0.66	15.45	1.59	5.00
142	INT574	Negative_regulation of C1S	9	0.47	11.25	1.41	5.00
143	INT201463	Negative_regulation of CCNE2	7	0.39	3.31	1.36	5.00
144	INT3816	Gene_expression of Ahr	13	0.65	7.51	1.31	5.00
145	INT14205	Regulation of KLK1	10	0.60	4.38	1.28	5.00
146	INT11496	Negative_regulation of F12	6	0.59	3.41	1.27	5.00
147	INT156672	Localization of SERPING1	10	0.74	12.15	1.25	5.00
148	INT49013	Gene_expression of Por	6	0.75	2.19	1.22	5.00
149	INT53285	Gene_expression of Cyp2c11	20	0.76	5.43	1.17	5.00
150	INT175652	Positive_regulation of BPHL	9	0.44	17.98	1.14	5.00
151	INT103043	Binding of PDE5A	16	0.37	7.79	1.12	5.00
152	INT96873	Gene_expression of CYP1B1	28	0.78	11.81	1.09	5.00
153	INT34586	Positive_regulation of Negative_regulation of HSD11B1	6	0.49	4.39	1.05	5.00
154	INT128609	Gene_expression of C1S	18	0.75	17.36	0.98	5.00
155	INT144482	Negative_regulation of Gene_expression of SERPING1	8	0.43	6.06	0.89	5.00
156	INT35141	Regulation of PLG	6	0.44	2.64	0.85	5.00
157	INT141591	Negative_regulation of Positive_regulation of GPT	2	0.42	0.83	0.8	5.00
158	INT96879	Positive_regulation of CYP1B1	14	0.70	5.73	0.78	5.00
159	INT327119	Gene_expression of HCCS	1	0.12	2.47	0.74	5.00
160	INT2395	Binding of MB	18	0.36	7.53	0.68	5.00
161	INT208371	Localization of Ahr	2	0.50	1.9	0.66	5.00
162	INT219793	Negative_regulation of Renbp	5	0.13	3.42	0.61	5.00
163	INT174106	Binding of Renbp	18	0.24	15.82	0.58	5.00
164	INT248682	Gene_expression of Rxrb	8	0.60	1.41	0.58	5.00
165	INT145530	Negative_regulation of Positive_regulation of KLK1	2	0.42	1.02	0.57	5.00
166	INT205619	Regulation of Renbp	6	0.17	1.91	0.55	5.00
167	INT327116	Positive_regulation of Localization of AES	4	0.22	2.69	0.55	5.00
168	INT173801	Gene_expression of Ik	11	0.36	1.31	0.51	5.00
169	INT221932	Gene_expression of F12	4	0.66	2.61	0.5	5.00
170	INT327120	Positive_regulation of Positive_regulation of MRI1	1	0.05	0	0.5	5.00
171	INT175759	Gene_expression of ARNTL	9	0.75	0.8	0.44	5.00
172	INT55807	Negative_regulation of GPT	4	0.42	4.11	0.44	5.00
173	INT88678	Gene_expression of CYP27B1	8	0.75	2.11	0.41	5.00
174	INT197012	Regulation of Gene_expression of LDLR	4	0.40	1.31	0.4	5.00
175	INT327121	Positive_regulation of Gene_expression of HCCS	1	0.07	1.3	0.37	5.00
176	INT316315	Negative_regulation of Binding of SERPING1	2	0.37	1.4	0.34	5.00
177	INT184641	Regulation of TRGC1	4	0.40	2.84	0.34	5.00
178	INT45040	Positive_regulation of Gene_expression of IGLL1	4	0.59	1.59	0.33	5.00
179	INT81196	Regulation of T2	3	0.11	1.92	0.33	5.00
180	INT120525	Gene_expression of SLCO1B3	2	0.57	1.47	0.33	5.00
181	INT274379	Negative_regulation of Binding of SERPINE1	1	0.03	0.91	0.33	5.00
182	INT118610	Localization of BPHL	6	0.57	6.88	0.33	5.00
183	INT302888	Positive_regulation of HIST1H4PS1	3	0.05	1.52	0.32	5.00
184	INT174112	Positive_regulation of Gene_expression of KRT19	4	0.44	4.28	0.31	5.00
185	INT232021	Positive_regulation of Gene_expression of SERPING1	8	0.49	4.99	0.31	5.00
186	INT158730	Gene_expression of Plxna3	4	0.65	1.82	0.29	5.00
187	INT75006	Gene_expression of Gstm1	6	0.45	2.19	0.29	5.00
188	INT174519	Gene_expression of C1R	4	0.35	0.51	0.29	5.00
189	INT26453	Binding of KLK1	2	0.47	0.84	0.28	5.00
190	INT232024	Protein_catabolism of KLK1	2	0.64	1.21	0.28	5.00
191	INT257785	Positive_regulation of KIN	3	0.45	0.72	0.24	5.00
192	INT113989	Regulation of Gene_expression of CCND1	11	0.44	7.57	0.24	5.00
193	INT96885	Localization of CYP1B1	4	0.80	2.11	0.23	5.00
194	INT41984	Regulation of Gene_expression of HSD11B1	4	0.44	4.18	0.23	5.00
195	INT96888	Negative_regulation of Gene_expression of CYP1B1	5	0.43	1.13	0.23	5.00
196	INT96883	Positive_regulation of Gene_expression of CYP1B1	3	0.70	1.24	0.22	5.00
197	INT28719	Binding of T2	3	0.20	1.55	0.21	5.00
198	INT81197	Transcription of T2	2	0.17	1.37	0.21	5.00
199	INT228644	Positive_regulation of Negative_regulation of SERPING1	5	0.46	4.21	0.21	5.00
200	INT260372	Transcription of Das	2	0.09	1.6	0.19	5.00